The "flying medics" will be based at Caernarfon Airport, along with a new helicopter and rapid response vehicle.
South and mid Wales have had the Emergency Medical Retrieval and Transfer Service Cymru since 2015 and it will launch in the north on Monday.
The health secretary said it would bring critical care closer to people.
Vaughan Gething added that enhancing the existing service from Caernarfon would ensure the region had the same emergency cover as the rest of Wales.
The Wales Air Ambulance (WAA) helicopters were originally staffed by paramedics.
But two years ago, emergency department consultants were recruited to be on board.
It meant they were able to give casualties blood transfusions, administer anaesthetics, offer strong painkillers and conduct a range of medical procedures not normally performed outside of a hospital - all at the scene of an incident.
Two "flying medics" helicopters are already based at Dafen in Carmarthenshire and in Welshpool, Powys.
Dr Ami Jones, EMRTS Cymru interim national director, said the new service would improve cover for north Wales, as well as Powys and parts of Ceredigion.
"Wales can pride itself on having established platinum-standard critical care across all of the country, via the WAA's bases in north, mid and south Wales," she said.
An independent evaluation by the Farr Institute at Swansea University revealed the Welsh flying medics service has already had a positive impact on critical care in Wales.
Results indicated:

Seren Bernard, 14, took her own life while living with foster carers in Pembrokeshire in 2012.
A serious case review was published in 2014, but Sarah Pollock was only given a summary of its contents.
A fresh call was made to Pembrokeshire council on Thursday, but it said it could not disclose the full report based on "clear legal advice".
Cabinet member for wellbeing, Tessa Hodgson, said: "On a personal level I can sympathise with the request. I think if any of us were named in an official document they would want to read the full report".
But she said the council had received "clear legal advice" and "that it is not within the gift of this council to disclose the full report".
The summary of the report said Seren, referred to as child M, had made a suicide attempt in 2011, and research indicated a further attempt "was a possibility".
"However, in the days prior to her death, her mood is recorded to have lifted and her behaviour gave no indication that she was contemplating suicide," it read.
It concluded: "It must remain uncertain whether there were any steps, if taken, would have prevented child M's death."
Ms Pollock said the report was a "document for learning" but questioned how lessons could be learned when "it was in lock down".
She said not knowing the contents of the report had left her feeling "traumatised and dysfunctional" as "so many questions have been left unanswered".
Speaking after the full council, she said she was "absolutely appalled" by the decision.
She said she would continue to campaign as the report was a "matter of public interest" and it was "her right to sight".
Specialist doctors are to join Wales Air Ambulance crews in north Wales for the first time in a bid to treat seriously injured patients faster.
[NEXT_CONCEPT]
A "distraught" mother has been denied access to a full report into the death of her teenage daughter while in care.