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Updated: Feb 11, 2022
During the first six months of the coronavirus disease 2019 (COVID-19) pandemic, the U.S. Food and Drug Administration (FDA) and the Federal Trade Commission (FTC) issued warning letters to seven companies for selling fraudulent COVID-19-focused products. These products included teas, essential oils, tinctures and colloidal silver – all of which are utilized by many dietary supplement manufactures. The companies were asserting that their products treat, cure or prevent COVID-19, a serious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (FDA, 2020). U.S. federal regulations provide the ability for dietary supplement manufacturers to make structure/function claims, that is, statements with respect to the supplement’s effects on the body’s structure or function. They may not, however, claim their products “…diagnose, mitigate, treat, cure, or prevent a specific disease or class of diseases” (21 U.S.C. 343(r)(6)). This is because dietary supplements that bear such claim may cause consumers to delay or stop appropriate medical treatment, leading to serious and life-threatening harm (FDA, 2020). Depending on the phrasing, or the context in which it is presented, a statement about the effect of a product on the structure or function of the body may lead consumers to believe that the product is beneficial for the treatment or prevention of a disease. The following demystifies the line of what is and is not a structure/function claim for a dietary supplement product by describing (1) the meaning of a structure/function claim (and related claims); (2) the regulatory framework and history; and (3) non-acceptable versus acceptable claims.
What is a structure/function claim?
A structure/function (S/F) claim is a statement addressing the role of a specific substance in maintaining normal healthy structure or function of the human body. This should not be confused with a health claim, which is a statement describing a relationship between a substance and reduced risk of a disease or health-related condition, such as “adequate calcium throughout life may reduce the risk of osteoporosis” (FDA, 2018). S/F claims (1) describe the role of a nutrient or dietary ingredient on the structure or function in humans (e.g., “calcium builds strong bones”); or (2) characterize the documented mechanism by which a nutrient or dietary ingredient acts to maintain such structure or function (e.g., “fiber maintains bowel regularity” or “antioxidants maintain cell integrity”) (FDA, 2018; 21 CFR § 101.93(f)).
There are two types of dietary supplements claims related to S/F claims, described below.
General well-being claims: These describe general well-being from consumption of a nutrient or dietary ingredient (g., “zinc will help you feel healthy”).
Nutrient-deficiency disease claims: These describe a benefit related to a nutrient deficiency disease like vitamin C and scurvy. Such claims are only allowed if the claim also states how widespread the stated disease is in the United States (FDA, 2018).
Since the enactment of the Dietary Supplement Health and Education Act (DSHEA) of 1994, FDA has lacked authority to approve structure/function claims (and related general well-being and nutrient-deficiency disease claims) before the dietary supplement products enter the market. However, a manufacturer must submit a notification with the text of the claim to FDA no later than 30 days after putting the dietary supplement product on the market. Manufacturers must also have competent and reliable scientific evidence to show that the claim is truthful and not misleading, but they do not have to submit the substantiation to FDA. The product label must include a disclaimer stating that FDA has not reviewed the claim and that the product is not intended to “diagnose, treat, cure, or prevent any disease,” because only a drug can legally assert such a claim (FDA, 2018; 21 CFR § 101.93). FDA has the authority to protect consumers from companies selling unapproved products and making false or misleading claims, including, issuing warning letters, product seizures, injunctions or criminal prosecutions against products and firms or individuals that violate the law (FDA, 2021).
DSHEA set forth a regulatory framework for dietary supplements that previously did not exist, and was a response by the U.S. Congress to FDA’s aggressive approach to regulating dietary supplements (Kaczka, 2000). Before the enactment of DSHEA, dietary supplement products (including vitamins and minerals) were subject to be regulated as a drug: (1) if “disease claims” were made (i.e., claims to diagnose, treat, cure, or prevent disease); (2) if claims were made to affect the structure or function of the body through a non-nutritive mechanism; or (3) if there was other evidence that the intended use of the product was as a drug. Dietary supplements with such claims had to meet the rigorous drug safety and efficacy requirements of the Federal Food, Drug, and Cosmetic Act (FD&C Act), including in nearly all cases, pre-market approval (FDA, 1999).
Congress passed DSHEA with the intent “…to strike the right balance between providing consumers access to both products and truthful information about the products while retaining authority for FDA to take action against products that present safety problems or are improperly labeled” (FDA, 1999). DSHEA not only created a broad comprehensive definition of “dietary supplements,” but also allowed retailers to sell third-party books and other educational materials concerning dietary supplements (Kaczka, 2000). Increasing information on dietary supplements to the public was considered by Congress as an inexpensive way to promote public health (Kaczka, 2000); a decision that was possibly motivated by President Clinton’s health care plan of 1993.
Additionally, DSHEA amended the FD&C Act to allow for certain types of claims for dietary supplements that formerly would have made them drugs, including claims concerning the supplement’s effects on the body’s structure or function through a non-nutritive mechanism (FDA, 1999). Dietary supplements may bear authorized health claims, but Congress prohibited dietary supplements to be intended to treat, prevent, mitigate, cure, or diagnose disease. Congress recognized that if dietary supplements were allowed to make disease treatment and prevention claims without pre-market review, the burden would be on consumers to evaluate the validity of countless claims about products marketed for serious and life-threatening conditions. Through the lack of pre-market review, dietary supplements would also be given an unfair advantage in the marketplace of prescription and over-the-counter (OTC) drugs (FDA, 1999).
What a structure/function claim is not
As mentioned before, a S/F claim is not a statement that claims, explicitly or implicitly, to diagnose, mitigate, treat, cure, or prevent disease. Such statements are described as “disease claims.” However, under DSHEA, the distinction between a S/F claim and a disease claim was not clear. This resulted in FDA drawing a line between the two types of claims. On January 6, 2000, FDA published a final rule in the Federal Register (65 FR 1000), defining the types of statements that can be made concerning the effect of a dietary supplement on the structure or function of the body. The regulations establish criteria for determining when a statement about a dietary supplement is a claim to diagnose, cure, mitigate, treat, or prevent disease. This action was intended to clarify the types of claims that may be made for dietary supplements without prior review by FDA and the types of claims that require prior authorization as health claims or prior approval as drug claims (FDA, 2000).
According to the final rule, in recognizing what is and is not an acceptable S/F claim for dietary supplements, it is first important to identify what constitutes a disease claim. Under 21 CFR § 101.93(g)(1), “disease” is defined as:
“…damage to an organ, part, structure, or system of the body such that it does not function properly (e.g., cardiovascular disease), or a state of health leading to such dysfunctioning (e.g., hypertension); except that diseases resulting from essential nutrient deficiencies (e.g., scurvy, pellagra) are not included in this definition.”
The definition of disease does not refer to signs or symptoms but claims that mention them will still be considered disease claims (21 CFR § 101.93(g)(2)(ii)). A test to make it easier to recognize what will be considered a sign or symptom is to ask oneself, “…whether the labeling suggests that the product will produce a change in the characteristic signs or symptoms of a specific disease or class of diseases” (FDA, 2000). Examples of statements that refer (explicitly or implicitly) to an effect on a specific disease or the characteristic signs or symptoms of such disease include “improves joint mobility and reduces inflammation” (characteristic symptoms of rheumatoid arthritis) and “lowers cholesterol” (characteristic symptom associated with stroke and heart disease) (FDA, 2000). It is the specificity of the signs or symptoms that prohibits these claims on dietary supplement. Examples of acceptable S/F statements include “promotes joint health and flexibility” and “helps maintain cholesterol levels that are already in the normal range” (FDA, 2000), which are not specific enough to imply reference to a specific disease or class of diseases.
This distinction between a S/F claim under 21 CFR § 101.93(g)(2)(i–ii), however, can be ambiguous and dependent on interpretation. For example, should the claim ‘‘maintains healthy cholesterol levels’’ be an acceptable S/F claim, while ‘‘lowers cholesterol’’ be treated as a non-acceptable (disease claim) for a dietary supplement product? As stated by a major trade association, “what is healthy cholesterol, but a lower cholesterol level?” According to FDA, references to ‘‘healthy’’ cholesterol may be misleading to consumers because the phrase ‘‘healthy cholesterol’’ is frequently used to refer to high density lipoproteins (HDL), a specific cholesterol fraction believed to be beneficial. To avoid this confusion, FDA determined that an appropriate S/F claim for maintaining cholesterol would be ‘‘helps to maintain cholesterol levels that are already within the normal range.” Maintaining cholesterol levels within the normal range is essential to the structure and function of the body for reasons besides prevention of heart disease (FDA, 2000).
Additionally, common conditions associated with natural states or processes (e.g., menopause, pregnancy, aging) that do not cause significant or permanent harm are acceptable S/F claims (FDA, 2000). For example, hot flashes, common symptoms associated with the menstrual cycle, ordinary morning sickness associated with pregnancy, mild memory problems associated with aging, hair loss associated with aging, and noncystic acne are not diseases under 21 CFR § 101.93(g)(2)(iii). Therefore, the claim “morning sickness associated with pregnancy” is identified as a S/F claim. However, abnormal conditions that are uncommon or can cause significant or permanent harm like senile dementia, toxemia of pregnancy, severe depression associated with the menstrual cycle, and cystic acne are treated as diseases under 21 CFR § 101.93(g)(2)(iii) (FDA, 2000). Therefore, the claims “toxemia of pregnancy” and “severe depression associated with the menstrual cycle” are identified as disease claims.
Under 21 CFR § 101.93(g)(2)(iv), other aspects of the labeling of a dietary supplement product may also constitute a disease claim. This includes explicit or implicit disease claims made in a product’s name, formulation, or reference of a publication title (refer to Table 1 for examples). The “use of pictures, vignettes, symbols, or other means” that portray an effect on a disease or diseases is also considered a disease claim. For example, an image of a woman wearing a mask may imply a claim that promotes the product’s ability to protect consumers against COVID-19 (National Advertising Division (NAD), 2020); this is a non-acceptable claim for a dietary supplement product.
Some product class names are so strongly associated with use to treat or prevent a specific disease or class of diseases that claiming membership in the product class implies disease treatment or prevention. The following examples of product class names imply disease treatment or prevention under 21 CFR § 101.93(g)(2)(v): claims that the product is an ‘‘antibiotic,’’ an ‘‘analgesic,’’ an ‘‘antiviral,’’ an ‘‘antimicrobial,’’ an ‘‘antidepressant,’’ or a ‘‘vaccine” (FDA, 2000). An acceptable S/F claim would state that a product is in a class that is not recognizable to health care professionals or consumers as intended for use to diagnose, mitigate, treat, cure or prevent disease, for instance, claims that the product is an ‘‘energizer,’’ a ‘‘rejuvenative,’’ a ‘‘revitalizer,” or an “adaptogen.” Although obesity is a disease, being overweight is not; therefore, ‘‘appetite suppressant’’ is also an acceptable S/F claim in the context where it does not imply use for obesity (FDA, 2000).
S/F claims do not suggest that the product has a role in the body’s response to a disease or to a vector of disease. A general reference to an effect on a body system that does not imply prevention or treatment of a disease state is an acceptable S/F claim. For example, “supports the immune system” is a S/F claim, whereas “supports the body’s antiviral capabilities’’ is a disease claim (FDA, 2000). The distinction between the two claims is one of specificity and an understanding of the immune system. The immune system has several functions other than fighting disease in the body; for example, the white blood cells of the immune system play an essential role in the phagocytosis and disposal of aging red blood cells or otherwise damaged cells. Therefore, the statement, “supports the immune system”, by itself, conveys no specific reference to the disease-fighting function of the immune system. In contrast, the claim that a product ‘‘supports the body’s antiviral capabilities’’ specifies a role in the body’s response to a specific class of diseases, those caused by viruses (e.g., colds, hepatitis, or HIV infection) (FDA, 2000).
Moreover, S/F claims are not to mention a therapy for disease. For example, the statement ‘‘helps maintain intestinal flora’’ alone, without any reference to a disease, drug, drug action, or therapy, does not imply an effect on disease and would be considered a S/F claim about general health maintenance. However, the statement, ‘‘helps individuals using antibiotics to maintain normal intestinal flora” is an implied disease prevention claim. This is because certain antibiotics can suppress normal intestinal flora that are used to prevent infection in the intestinal tract, which may result in overgrowth in the gut of a pathogenic organism (FDA, 2000).
Under 21 CFR§ 101.93(g)(2)(x), a statement is considered a disease claim if it “otherwise” suggests an effect on a disease or a class of diseases. This provision is necessary to allow for implied disease claims that may not fit into the nine enumerated criteria (21 CFR § 101.93(g)(2)(i–ix). FDA developed the criteria of what constitutes a disease claim based on past experience and recognizes the possibility that other types of statements may also imply disease treatment or prevention (FDA, 2000). Does that mean FDA can classify any S/F claim as a disease claim? – no, it does not; to regulate a statement as a disease claim, FDA has to show that the statement implies an effect on disease.
The table below summarizes how to identify what is and is not an acceptable S/F claim for a dietary supplement product.
Table 1. Identifying non-acceptable and acceptable structure/function claims for dietary supplement products.)
Non-acceptable claim (disease claim)
Acceptable claim (structure/ function claim)
1. Do not suggest an effect on a specific disease or class of disease.
“Improves joint mobility and reduces inflammation” (implies treatment for a disease, rheumatoid arthritis).(b)
“Promotes joint health and flexibility.”
2. Do not suggest that the product will produce a change in the characteristic signs or symptoms of a specific disease or class of diseases.
(characteristic signs or symptoms associated with stroke and cardiovascular disease).(b)
“Helps maintain cholesterol levels that are already in the normal range” (maintaining normal function, not a disease).(c)
3. May refer to a natural state (e.g., aging, pregnancy) generally but may not mention an abnormal condition that is uncommon or can cause significant or permanent harm.
“Toxemia of pregnancy” (toxemia is an abnormal condition that is uncommon and can cause significant or permanent harm).(c)
“Morning sickness associated with pregnancy” (morning sickness is a common, mild abnormality associated with pregnancy).(c)
4. Do not suggest an effect on a disease or diseases through:
A) product name;
‘‘CircuCure’’; ‘‘Soothing Sleep’’(c)
B) product formulation;
Products that contain aspirin, digoxin, or laetrile (drugs that are known for its use in preventing or treating a disease).(c)
C) citation of publication titles;
“The Role of Zinc in Antiviral Immunity.” Adv Nutr. 2019;10(4):696-710. (title refers to specific class of diseases, those caused by viruses)
“Zinc and its importance for human health: An integrative review.” J Res Med Sci. 2013;18(2):144-157.
D) the use of the term “disease” or “diseased”; or
‘‘Promotes good health and prevents the onset of disease’’ (product itself will achieve the intended effect).(c)
‘‘A good diet promotes good health and prevents the onset of disease.”(c)
E) the use of pictures, vignettes, symbols, or other means.
Picture of an abnormal tissue or organ.(b)
Pictures of healthy organs
(Exception: symbols, like the heart symbol, that are widely associated with disease treatment and prevention). (b)
5. Do not suggest membership to a class of products that are strongly associated with use to treat or prevent a specific disease or class of diseases.
Claims that the product is an ‘‘antibiotic,’’ an ‘‘analgesic,’’ an ‘‘antiviral,’’ an ‘‘antimicrobial,’’ an ‘‘antidepressant,’’ or a ‘‘vaccine.”(c)
Claims that the product is an ‘‘energizer,’’ a ‘‘rejuvenative,’’ a ‘‘revitalizer,’’ or an ‘‘adaptogen.’’(c)
6. Do not suggest that the product is a substitute for a product that is a therapy for a disease.
(makes a direct connection with an approved drug)(c)
‘‘Use as part of your weight loss plan’’ (not specific enough; obesity is a disease but overweight is not)(c)
7. Do not suggest that the product augments a particular therapy or drug action that is intended to diagnose, mitigate, treat, cure, or prevent a disease or class of diseases.
‘‘Use as part of your diet when taking insulin to help maintain a healthy blood sugar level.’’(c)
“Use as part of a healthy diet to help maintain healthy blood sugar levels.”(c)
8. Do not suggest that the product has a role in the body’s response to a disease or to a vector of disease.
‘‘Supports the body’s antiviral capabilities.’’(c)
“Supports the immune system.”(c)
9. Do not suggest that the product treats, prevents, or mitigates adverse events associated with a therapy for a disease, if the adverse events constitute diseases.
‘‘Helps individuals using antibiotics to maintain normal intestinal flora.’’(c)
‘‘Helps maintain healthy intestinal flora.’’(c)
10. Do not “otherwise” suggests a disease or disease condition. This does not mean FDA can classify any structure/ function claim as a disease claim.
To regulate a statement as a disease claim, FDA would have to show that the statement implied an effect on disease.(c)
‘‘Provides nutritional support for women during premenstruation by promoting proper fluid balances and breast health” (not a disease claim, despite the critics who thought it would be under this criterion).(c)
(a)Based on 21 CFR § 101.93(g)(2)(i–x); (b)Example/ explanation from FDA (2002); (c)Example/ explanation from FDA (2000).
On first review, statement for a dietary supplement may look like a structure/function claim, but in fact it is possible that FDA would likely view the claim as a disease claim. The distinction between the two claims is largely based on specificity, context, and interpretation. Burdock Group can work with dietary supplement manufacturers to assess whether a claim or claims is acceptable for their product(s) and to assist with submitting the claim(s) to the proper regulatory authority or governmental bodies.
FDA (1999) Statement of Jane E. Henney, Commissioner, Food and Drug Administration In: Dietary Supplement Health and Education Act: Is the FDA Trying to Change the Intent of Congress?: Hearing Before the House Comm. On Government Reform, 106th Congr., 1st Sess. U.S. Government Printing Office, Washington, D.C., pp. 33–50.
FDA (2000) 65 FR 1000 – Regulations on Statements Made for Dietary Supplements Concerning the Effect of the Product on the Structure or Function of the Body. Federal Register. 65(4):1000–1050.
FDA (2002) Small Entity Compliance Guide on Structure/Function Claims. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/small-entity-compliance-guide-structurefunction-claims#N_1_ (site accessed 14Sep2021).
FDA (2018) Label Claims for Conventional Foods and Dietary Supplements . https://www.fda.gov/food/food-labeling-nutrition/label-claims-conventional-foods-and-dietary-supplements (site accessed 29Sep2021).
FDA (2020) Coronavirus Update: FDA and FTC Warn Seven Companies Selling Fraudulent Products that Claim to Treat or Prevent COVID-19. https://www.fda.gov/news-events/press-announcements/coronavirus-update-fda-and-ftc-warn-seven-companies-selling-fraudulent-products-claim-treat-or (site accessed 2Oct2021).
FDA (2021) Fraudulent Coronavirus Disease 2019 (COVID-19) Products. https://www.fda.gov/consumers/health-fraud-scams/fraudulent-coronavirus-disease-2019-covid-19-products (site accessed 2Oct2021).
Kaczka, K.A. (2000) From Herbal Prozac to Mark McGwire’s Tonic: How the Dietary Supplement Health and Education Act Changed the Regulatory Landscape for Health Products. Journal of Contemporary Health Law and Policy. 16(2):463–499.
National Advertising Division (NAD) (2020) Social Media Post Implying Continual-G Glutathione Enhancer Protects Against COVID-19 is Discontinued Following NAD Inquiry. https://bbbprograms.org/media-center/newsroom/social-media-post-implying-continual-g-glutathione-enhancer-protects-against-covid-19-is-discontinued-following-nad-inquiry (site accessed 2Oct2021).


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If you’re looking for a vitamin supplement that can help you meet your needs for B vitamins and vitamin E, look no further than Neurogen E!
Discover everything you need to know about Neurogen E – from its product description, health benefits, ingredients, dosage instructions, and more!
There are 6 basic types of nutrients that are considered vital to life: water, carbohydrates, fats, proteins, minerals, and vitamins. These nutrients are necessary for your body to function properly, and your diet is the best source of them.
However, if you’re not getting enough vitamins from your diet, or if you’re looking to boost your vitamin intake, taking a supplement such as Neurogen E can help you.
In this article, we discuss everything you need to know about Neurogen-E – from its product description, health benefits, ingredients, dosage instructions, and more!
Neurogen E Product Description
What is Neurogen E?
Neurogen E is a B-vitamin complex(vitamins B1, B6, and B12) and vitamin E supplement intended to provide relief for the nerves. It contains the optimum amount necessary to help treat vitamin B deficiency as manifested by loss of reflexes in the hands, knees, and feet; abnormal touch sensation (pricking and burning), and muscle pain.
Neurogen-E contains 3X MORE Vitamin B1 (300mg), 5X MORE Vitamin B12 (1000mcg), with Vitamin B6 (100mg), and added Vitamin E (100IU) compared to other major over-the-counter B-complex vitamins.
Neurogen-E is manufactured and distributed by Unilab, Inc.
About Unilab, Inc. Unilab is a pharmaceutical company committed to providing world-class medicines.
“Our Purpose: Working towards a healthier Philippines, one quality medicine at a time.
We believe that all Filipinos have the right to quality healthcare. This is why we are committed to bringing world-class medicines within your reach.
Our Commitment to Quality: We believe all our customers deserve products and services made with quality every step of the way. Because of this, Unilab adheres to the strictest standards of quality throughout its supply chain, from sourcing raw and packaging materials to manufacturing and distribution, to ensure the safety and efficacy of its products consistently.
Quality is one of the company’s priorities. That is, to be able to assure you that our products are consistently safe and effective, we make sure our facilities go beyond compliance when it comes to quality control. From research and development to manufacturing, and even up to the distribution of our products to your location – we strive to keep our promise of quality to you.”
Neurogen E Benefits
Of the 13 vitamins that your body requires to stay healthy, the B vitamins make up more than half of them. They’re a group of 8 vitamins that naturally occur in a range of different foods, but some people may not be getting enough of every single B vitamin from their diet.
Each B vitamin plays a unique role in the body. But as a group, they are best known for helping the body unlock the energy it needs to function well.
- B vitamins, including vitamins B1, B2, B5, and B6, play a role in cellular energy production.
- Vitamin B12 supports normal blood production and vitamin B3 is involved in DNA repair and supports healthy skin.
- Vitamins B1, B2, and B6 support the healthy functioning of the nervous system.
Aside from the B vitamins, getting enough vitamin E is essential for your well-being as well. Vitamin E is a nutrient that’s important to reproduction, vision, and the health of your brain, blood, and skin. Vitamin E also has antioxidant properties. Vitamin E deficiency can cause nerve pain (neuropathy).
If you’re looking for a vitamin supplement that can help you meet your needs for B vitamins and vitamin E, look no further than Neurogen-E!
Neurogen-E is used for the treatment of B-vitamin deficiencies (vitamins B1, B6, B12), as well as vitamin E deficiencies manifested as: loss of reflexes in the hands, knees, and feet; abnormal touch sensation (pricking and burning), and muscle pain.
Neurogen-E is used for the treatment of conditions responsive to high-dose vitamins B1, B6, B12, and E, including:
- Diabetic neuropathy
- Pernicious anemia
- Sideroblastic anemia
- Wernicke’s disease
|Thiamine (B1)||Involved in the production and release of acetylcholine, a neurotransmitter required in conveying signals within nerve cells|
|Pyridoxine (B6)||Required in the formation of neurotransmitters such as serotonin, gamma amino butyric acid (GABA), dopamine, and epinephrine to facilitate normal nervous system function|
|Cyanocobalamine (B12)||Required for the synthesis of myelin, the white sheath that surrounds nerve fibers|
|Vitamin E||Helps maintain membrane integrity in all cells of the body including nerve tissues by acting as the body’s major lipid-soluble chain-blocking antioxidant|
Neurogen E Features and Ingredients
Neurogen-E contains B-complex vitamins (Vitamins B1, B6, and B12) and Vitamin E.
|Each film-coated caplet contains:|
|Vitamin E||100 IU|
|Thiamine Mononitrate (Vitamin B1)||300 mg|
|Pyridoxine Hydrochloride (Vitamin B6)||100 mg|
|Cyanocobalamin (Vitamin B12)||1 mg|
Neurogen-E How to Use
Below are some answers to frequently asked questions when it comes to Neurogen-E dosage and use:
How often should you take Neurogen-E?
Neurogen E should be taken orally. Take one tablet daily or as directed by your doctor.
When is the best time to take Neurogen-E?
There is no specific time prescribed to take Neurogen-E. You may take it anytime during the day.
How should it be stored?
To store Neurogen E, make sure to:
- Keep it out of sight and reach of children.
- Store at temperatures not exceeding 30o Celsius.
- Protect from light.
What should you do if you miss a dose?
If you miss a dose, just take the next dose and the succeeding doses at the usually recommended schedule (i.e. once a day). Do NOT double the dose.
Can a child take Neurogen-E?
Neurogen E is recommended to be taken by adults, 18 years old and above. If you would like to give it to someone below 18 years old, consult your child’s pediatrician/doctor since they are in the best position to advise what is most suitable based on your child’s age, nutritional needs, and overall health status.
Can pregnant or breastfeeding women take Neurogen-E?
As a general precaution, it is always best to consult your doctor/OBGYN before taking any medicine or supplement.
When should you NOT take Neurogen-E?
You should NOT take Neurogen-E:
- If you are allergic to any ingredient in the product
- Cyanocobalamin is contraindicated in people who have experienced hypersensitivity reactions to cobalt
- Cyanocobalamin should not be used in patients with early Leber’s disease, since rapid wasting of the optic nerve has been reported following its administration to these patients
Neurogen E User Reviews
Here’s what people are saying about Neurogen-E:
“Value for money.” – G
“My husband has been taking this and it helps.” – S
“Highly recommended po, my son is using this…” – Elsa Pleto
“Magaling talaga.kasi ilang linggo ko nang iniinda ang braso ko laging makirot at namamanhid ..siguro gawa nga na nag luluto at nag huhugas ako ….since two days ko pa lang syang ginamit…very effective talaga ..salamat Neurogen-E.” – Reylucy Seberre
“Yes sobrang favorite ko po ito… sobrang trusted ko na po itong vitamins sobrang laking tulog lalo na kung working woman ka.” – Maricon Guevarra
“Ako nag Neurogen-E nawala na ang problema sa akong kamay nga maminhod mayron tusok-tusok salamat sa Neurogen-E.” – Marcelino Sepe
“Infairness po nawala po tlaga yung palaging kumikirot at sumasakit ko na mga joint at nerve.” – Norhana Oyas Sarip
“Gumagamit na po ako nito dalawang linggo na pero para pong walapa rin po akong nararamdamang pagbabago iniisip ko po na baka d na po nababagay sa idad ko 75 na po ako.” – Leonora Manguera
“Galing talaga Neurogen E!!isa ako sa nagamit nito at gumaling ang sakit kamay ko.” – Jepoy Azucena
“Ok po yan maganda rin sa mga laging pagod at puyat pampalakas resistensya.” – Ron Sales
“Nabasa ko po ito sinukuan ko ngbili ako sa butika kc tinutusok tong hinlalaki paa masakit hirap ako maka2log ngaun na uminom ako wla ng tumutusok thank you sa gamot na ito na bilhin ko lage.” – Lhen Marantal
“Yes! I take Neurogen-E everyday.at totoo nawala na mga ngalay at manhid ng paa at kamay ko. Wala na rin pti lower back pain ko.dati halos every month nareresetahan ako ng Celebrex dhil sa sobrang pain..ngayon .halos di na ko inaaatake ng mga sakit sakit ng katawan pti migraine ko bihira na sumpungin.thanks Neurogen-E.. You made me well.” – Edz Hular
“Ito din supplement ko araw araw, matagal na ako gumagamit okey siya.” – Bebian Malinao
Neurogen E Price
The suggested retail price of Neurogen-E is PHP 14.00 per tablet.
*Prices may differ from one store to another.
Where to Buy Neurogen E
Neurogen-E is available in all leading drugstores nationwide.
You can also purchase Neurogen-E online by clicking on the link of your favorite Neurogen-E products.
Disclaimer: You should consult a licensed health care professional before starting any supplement, dietary, or exercise program, especially if you are pregnant or have any pre-existing medical conditions. All information contained on this website is for general information purposes only.


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If you are looking to buy Valium 10mg, Trinity Medstore is your trusted source. We understand the importance of providing high-quality medications at affordable prices, and we strive to meet the needs of our customers.
Valium, also known as diazepam, is a medication used to treat anxiety, muscle spasms, and seizures. It belongs to a class of drugs called benzodiazepines, which work by calming the brain and nerves. Valium is a prescription medication, and it is important to consult with a healthcare professional before starting any new medication.
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What We Offer
We are all about getting results and being committed to a fitness lifestyle that you’d actually love. Our broad range of services ensures that there is a program just right for you, ready and waiting to set you on your path to a life changing transformation!
PHOENIX SIGNATURE PROGRAMS
These programs are for men and women looking to get fitter and stronger, as well as helping them to burn body fat. The primary focus is to accelerate results of those who are close to a specific goal...
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What Our Members Say
2017 COMRADES MARATHON
“Alex did an extremely impressive and professional assessment on me – testing everything from flexibility to weak areas, strengths, fitness and mobility.
Based on the results, he tailor-made a program for me to reach the start line of Comrades. We had little time (approximately 5 Months) to lose the weight and gain the strength and fitness required. What I loved most about Alex’s approach was how conservative and sensitive he was to the weak points, totally avoiding any injuries”.
“After only a year of training with Phoenix, I entered one of their in-house Phoenix Challenges. I went from never having deadlifted before, to pulling a 130kg deadlift (more than double my body weight), followed by 4 pull-ups and 105 x 16kg kettlebell snatches in 5 minutes. I realised that I had the strength in me to overcome any obstacles that life threw at me.
Becoming stronger was the best thing I could have done for myself”.
MY NEW BEACH BODY
“December 2016 holidays were fast approaching and I needed my beach body – enter the Phoenix Body Transformation Challenge – a six-week training challenge complete with nutrition coaching – I signed up, added a Saturday group class to my training and embraced the nutrition coaching. Six weeks later I had lost 8kgs, 22cms and my body fat were down to 17% (I am 54 years old and my weight and body fat was down to the same as when I was 25).
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VICTORIOUS OVER BACK PAIN
“After a full assessment with Alex and lots of patience on his part and I suppose mine too (because I was impatient, wanting to get stronger and do more), I settled into personal training twice a week. I began my journey with Alex 4 years ago, in 2012, when I was 54 years old. I do weight training and have even deadlifted up to 1.25 x my body weight.
I have just turned 59 and I can attest to the fact that I no longer suffer from any back pain whatsoever, at any time of the day or night”.
“I was still struggling to lose weight, but Jay was patient and kept on motivating me. At the start of this year, we set goals (that I was conveniently avoiding before) that I would like to achieve and I have now lost 19kg’s and I am in better shape than what I have been in years.
He is always up to date with the latest training techniques and diet trends and will always give me tools and ideas if I feel I am not losing any weight. Training sessions are never boring and Jay always does a variety of routines. He is also very professional and personable and I always look forward to my next session”.
THE NEW THANDEKS
My clothes that were too tight for me are fitting me now. My body is much lighter and I am full of energy- “I think I can pull the wheel for a big truck” My self -esteem is back and I walk with confidence in front of people. I love what I see and feel. Feeling great. I have lost 5kg as at end of May 2017. Now weigh 85kg. Thank you, my Group Leaders at Phoenix, without your guidance and support I wouldn’t be weighing 5 kilos less.
I am still on my journey as I still have more Kilo’s to lose from this body. I know that I have the best Trainers at Phoenix and they will do the best to walk with me on my journey and meet my goal. “WATCH THIS SPACE”


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Sofzsleep is constantly on the lookout for innovative ways to improve our customers’ experiences. With the aid of frontline technology, Sofzsleep has made remarkable enhancement to their mattresses to provide better comfort and sleep quality for everyone. In 2018, besides looking splendid and feelin […]
Buying A Reasonably-Priced, Superior Latex Mattress Is Not As Difficult As It Sounds
With a massive variety of mattress’ materials, brands and price range available, shopping for a mattress can be quite daunting. When it comes to bedding materials, natural latex has become one of the most popular options amongst consumers, especially for those who have researched extensively about t […]
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Parenting is not a structured, manual-style journey with specific instructions. One of the major concern that many parents fret over surrounds their children’s sleep. More specifically, when is the right time for children to sleep in their own beds, and the benefits of doing so. Other than giving pa […]
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Have you ever experienced a strange sleep episode that left you in a state of confusion? Believe it or not, but there is a scientific explanation behind these weird sleep phenomena. We have listed below the top 8 most commonly experienced strange sleep encounters and its causes! 1. The ‘free-fall’ f […]
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Physically maturing every night, having a night of proper sleep is extremely important for a growing child. A general rule of thumb for the recommended amount of sleep for children is as follows – preschoolers (3 to 5 years old) requiring 10 to 13 hours of sleep and school-aged children (6 to 14 yea […]
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