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The Rise And Rise Of Holistic Wellness Retreats: Our Pick Of The Best From Around The World
Digital retreats, detox holidays, wellness spas… They seem to be popping up everywhere. Wellness breaks are huge business in 2016, and the market is only set to grow. Whereas previously retreats tended to focus on one specific aspect of health and wellness, an increasing number are now focusing on holistic wellbeing by incorporating fitness plans alongside nutrition programs, tech amnesties, daily yoga practices, meditation sessions, and the like.
Below we have complied a list of our favourite holistic wellness retreats from around the world:
COMO Shamble Estate, Bali
Gwinganna Lifestyle Retreat, Australia
Obonjan Island, Croatia
SHA Wellness Clinic, Spain
Canyon Ranch, USA

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Dietary Supplements: How Family Physicians Can Address Safety Concerns by Working with the FDA
Am Fam Physician. 2016 Jan 15;93(2):97-98.
The nation's physicians rely on the U.S. Food and Drug Administration (FDA)—the first consumer health protection agency created following the Pure Food and Drug Act of 1906—to safeguard all medical products prescribed for our patients. However, the FDA continues to have only limited oversight of more than 85,000 dietary supplements of uncertain effectiveness or safety, often used by patients without their family physician's knowledge.
That is why it was troubling to hear of the death of a healthy 18-year-old Ohio student attributed to an acute cardiac arrhythmia from an unintentional overdose of caffeine.1,2 The student athlete ingested about 1 teaspoon of a powdered caffeine product to enhance exercise performance, inadvertently consuming the equivalent of more than 30 cups of strongly brewed coffee in a single dose. Members of Congress and a respected food safety group, the Center for Science in the Public Interest, have called for FDA action to ban all bulk caffeine products sold directly to patients.3,4 In December 2014, the FDA announced that it was looking into this product safety issue and working on next steps.5 Since then, it has issued warning letters to several powdered caffeine manufacturers and updated its dietary supplements web page to include information on safety concerns for powdered caffeine products.6
Caffeine is regulated by the FDA as a food additive, dietary supplement, and drug, and it remains available for sale online in formulations that are dangerous because of the inability of our patients to determine a safe dose without a measuring scale. Promoted widely for its noticeable ergogenic effect during high-intensity exercise (e.g., weight training), powdered caffeine is used by adolescent athletes in the hope of enhancing workout performance.7–9 The 100- to 300-g containers sold online for $20 or less include 10 to 30 lethal doses of powdered caffeine.
Your patients are likely using some type of dietary supplement, whether they tell you or not. More than one-half of U.S. adults consume a dietary supplement daily, with use growing steadily over the past decade.10 Many supplements that claim to enhance specific elements of health (e.g., stamina, sexual performance, bone joint health, mental acuity) are found to be ineffective for the purported benefit or found to be toxic, harmful, or even deadly.11,12
Few patients or physicians understand that the FDA does not have the authority under current law to approve or monitor dietary supplements in the same rigorous fashion as its postmarket surveillance of prescription drugs.13 In contrast, consider the antihypertensive medication that you prescribed today. The FDA can assure you and your patient that the drug dispensed by the pharmacy is of the quality, security, and integrity expected in the United States—safe when used as specified in the prescribing information approved by the FDA.
The Dietary Supplement Health and Education Act (DSHEA) of 1994 made supplement manufacturers responsible for ensuring that their products are safe, essentially using an honor system. The supplement that your patient is taking under DSHEA is presumed to be safe and effective; manufacturers do not need FDA approval before selling their product. The FDA mainly depends on physicians and patients to recognize and report unexpected safety issues. This must occur before any steps can be taken to evaluate the safety signal, create a risk mitigation plan, warn the public of newly discovered safety concerns, and, if risk mitigation fails, remove the supplement from the market.14
Under authority recently granted by Congress, the FDA can now require dietary supplement manufacturers to report a serious adverse event when they become aware of it. Unfortunately, no active surveillance is required by the manufacturer,15 and it is estimated that the FDA receives reports for less than 1% of all serious adverse events associated with dietary supplement use.16,17
Under these constraints and faced with limited resources, the FDA has implemented a program that monitors products pulled from store shelves or sold online with claims for weight loss, improved sexual performance, and muscle growth. The agency is identifying many products that are sold with claims to be supplements but that instead have been adulterated with undeclared prescription drug ingredients, including corticosteroids, phosphodiesterase type 5 inhibitors, or sibutramine.18 Serious drug-drug interactions leading to hypertension or hepatic or cardiac toxicity have been documented.19,20
What can a physician do to support and protect patients from harm if they choose to use readily available dietary supplements? Don't expect a change in law or regulation anytime soon that would permit the type of monitoring we count on from the FDA to keep our prescription and over-the-counter medications safe. Instead, the FDA will continue to rely on primary care physicians to counsel and educate patients about supplement use. In recent years, excellent science-based information, including quick health professional references and patient fact sheets, has become easily accessible online from federal agencies and private sources.21–24 Most importantly, the FDA needs the active support of physicians in identifying and voluntarily reporting suspected serious adverse events or product quality concerns to MedWatch, the FDA reporting program (http://www.fda.gov/Safety/MedWatch/). These reports can then trigger the investigation, evaluation, and risk mitigation actions that can avert future patient harm from dietary supplement use.
REFERENCESshow all references
1. U.S. Food and Drug Administration. FDA consumer advice on powdered pure caffeine. http://www.fda.gov/food/recallsoutbreaksemergencies/safetyalertsadvisories/ucm405787.htm. Accessed March 19, 2015....
2. Mientka M. FDA warns of powdered caffeine's potentially lethal effects after accidental overdose, death of teen boy. Medical Daily. July 19, 2014. http://www.medicaldaily.com/fda-warns-powdered-caffeines-potentially-lethal-effects-after-accidental-overdose-death-teen-boy. Accessed March 19, 2015.
3. Center for Science in the Public Interest. FDA should ban retail sale of bulk caffeine, says CSPI. December 9, 2014. http://cspinet.org/new/201412091.html. Accessed March 19, 2015.
4. Charles E. Schumer United States Senator for New York. Following several tragic deaths, Schumer calls on the FDA to ban powdered caffeine [press release]. February 10, 2015. http://www.schumer.senate.gov/newsroom/press-releases/following-several-tragic-deaths-schumer-calls-on-the-fda-to-ban-powdered-caffeine_one-teaspoon-of-concentrated-powdered-caffeine-is-equivalent-to-25-cups-of-coffee-and-is-highly-dangerous-for-teens--young-adults-. Accessed March 19, 2015.
5. Landa MM; U.S. Food and Drug Administration. Tragic deaths highlight the dangers of powdered pure caffeine. December 16, 2014. http://blogs.fda.gov/fdavoice/index.php/2014/12/tragic-deaths-highlight-the-dangers-of-powdered-pure-caffeine/. Accessed March 19, 2015.
6. U.S. Food and Drug Administration. FDA takes action on bulk pure powdered caffeine products. September 1, 2015. http://www.fda.gov/food/newsevents/constituentupdates/ucm460097. Accessed November 16, 2015.
7. Cole KJ, et al. Effect of caffeine ingestion on perception of effort and subsequent work production. Int J Sport Nutr. 1996;6(1):14–23.
8. Denadai BS, Denadai ML. Effects of caffeine on time to exhaustion in exercise performed below and above the anaerobic threshold. Braz J Med Biol Res. 1998;31(4):581–585.
9. Davis JK, Green JM. Caffeine and anaerobic performance: ergogenic value and mechanisms of action. Sports Med. 2009;39(10):813–832.
10. Bailey RL, Gahche JJ, Miller PE, Thomas PR, Dwyer JT. Why US adults use dietary supplements. JAMA Intern Med. 2013;173(5):355–361.
11. Cohen PA, et al. Presence of banned drugs in dietary supplements following FDA recalls. JAMA. 2014;312(16):1691–1693.
12. Cohen PA. Hazards of hindsight—monitoring the safety of nutritional supplements. N Engl J Med. 2014;370(14):1277–1280.
13. Ashar BH, Rice TN, Sisson SD. Physicians' understanding of the regulation of dietary supplements. Arch Intern Med. 2007;167(9):966–969.
14. Fabricant D; U.S. Food and Drug Administration. FDA uses new authorities to get OxyElite Pro off the market. November 18, 2013. http://blogs.fda.gov/fdavoice/index.php/2013/11/fda-uses-new-authorities-to-get-oxyelite-pro-off-the-market/. Accessed March 19, 2015.
15. Frankos VH, Street DA, O'Neill RK. FDA regulation of dietary supplements and requirements regarding adverse event reporting. Clin Pharmacol Ther. 2010;87(2):239–244.
16. Woo JJ. Adverse event monitoring and multivitamin-multimineral dietary supplements. Am J Clin Nutr. 2007;85(1):323S–324S.
17. Gardiner P, Sarma DN, Low Dog T, et al. The state of dietary supplement adverse event reporting in the United States. Pharmacoepidemiol Drug Saf. 2008;17(10):962–970.
18. U.S. Food and Drug Administration. Tainted products marketed as dietary supplements. http://www.accessdata.fda.gov/scripts/sda/sdNavigation.cfm?sd=tainted_supplements_cder. Accessed March 19, 2015.
19. Centers for Disease Control and Prevention. Notes from the field: acute hepatitis and liver failure following the use of a dietary supplement intended for weight loss or muscle building—May–October 2013. MMWR Morb Mortal Wkly Rep. 2013;62(40):817–819.
20. Fong TL, Klontz KC, Canas-Coto A, et al. Hepatotoxicity due to hydroxycut: a case series. Am J Gastroenterol. 2010;105(7):1561–1566.
21. National Center for Complementary and Integrative Health. Herbs at a glance. https://nccih.nih.gov/health/herbsataglance.htm. Accessed May 22, 2015.
22. National Institutes of Health. Office of Dietary Supplements. Dietary supplement fact sheets. http://ods.od.nih.gov/factsheets/list-all. Accessed May 22, 2015.
23. National Institutes of Health. Dietary supplement label database. http://www.dsld.nlm.nih.gov/dsld/index.jsp. Accessed May 22, 2015.
24. Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com/home.aspx?cs=&s=ND&AspxAutoDetectCookieSupport=1. Accessed May 22, 2015.
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There are thousands of living organisms which are living in the mouth and some of them produce a fetid smell.
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About the Semiconductor Laser Treatment Market Medical lasers use focused light sources with precision to treat tissue. A laser light has a specific wavelength in a narrow beam, creating a high-intensity light. The use of lasers in the healthcare sector has proved to be a boon for both the semiconductor and medical industries. Lasers are used in medical treatment areas such as cosmetic dermatology for skin resurfacing, scar revision, tattoo removal, and laser hair removal; lithotripsy; ophthalmology; cancer treatment; dermatology; and general surgery for tissues. Technavio's analysts forecast the global semiconductor laser treatment market to grow at a CAGR of 11.22% during the period 2016-2020. Covered in this report The report covers the present scenario and the growth prospects of the global semiconductor laser treatment market 2016-2020. To calculate the market size, Technavio considers the revenue generated from the sales of laser devices to the following healthcare segments: Aesthetics: Laser-based aesthetic devices cover a range of functions such as pigmentary treatments, acne and rejuvenation applications, and skin tightening. Surgical: Lasers in surgical procedures are used to treat skin conditions such as vascular and pigmented lesions and scars. Ophthalmic: Ophthalmic lasers are therapeutic and diagnostic devices used in the field of ophthalmology. They are used to treat eye conditions such as tumors, glaucoma, diabetic retinopathy, retinal disorders, cataracts, and vision correction problems. Dental: Lasers in dentistry are used in the form of laser-assisted new attachment procedure (LANAP), laser-facilitated wound healing, and laser root planning. The market is divided into the following segments based on geography: Americas APAC Europe ROW Technavio's report, global semiconductor laser treatment market 2016-2020, has been prepared based on an in-depth market analysis with inputs from industry experts. The report covers the market landscape and its growth prospects over the coming years. The report also includes a discussion of the key vendors operating in this market. Key vendors Cutera Cynosure Lumenis Syneron Medical Topcon Other prominent vendors Alma Lasers Bausch & Lomb Body BeneFits CoolTouch Deka Laser Technologies Energist North America Ellipse Erchonia Fotana Iridex Sciton Market driver Growing awareness of use of lasers treatment in medical aesthetics For a full, detailed list, view our report Market challenge Risks associated with laser-based devices For a full, detailed list, view our report Market trend Shift toward non-invasive and pain-free procedures For a full, detailed list, view our report Key questions answered in this report What will the market size be in 2020 and what will the growth rate be? What are the key market trends? What is driving this market? What are the challenges to market growth? Who are the key vendors in this market space? What are the market opportunities and threats faced by the key vendors? What are the strengths and weaknesses of the key vendors? You can request one free hour of our analyst's time when you purchase this market report. Details are provided within the report.
Table of Contents
PART 01: Executive summary Highlights PART 02: Scope of the report Definition Base year and forecast period Market coverage Market size calculation Market segmentation Geographical segmentation Vendor segmentation Vendor offerings PART 03: Market research methodology Research methodology Economic indicators PART 04: Introduction Key market highlights PART 05: Market landscape Market overview Five forces analysis PART 06: Market segmentation by application Global semiconductor laser treatment market by application Global semiconductor laser treatment market by application 2015-2020 Aesthetics segment Surgical segment Ophthalmic segment Dental segment PART 07: Geographical segmentation Global semiconductor laser treatment market by geography 2015-2020 Americas EMEA APAC PART 08: Market drivers PART 09: Impact of drivers PART 10: Market challenges PART 11: Impact of drivers and challenges PART 12: Market trends Competitive Scenario PART 13: Vendor landscape Cutera Cynosure Lumenis Topcon Other prominent vendors PART 14: Market figure summary PART 15: Appendix List of abbreviations PART 16: Explore Technavio List of Exhibits
Exhibit 01: Segmentation of global semiconductor laser treatment market 2015 Exhibit 02: Key regions Exhibit 03: Product offerings Exhibit 04: Common medical laser systems and their wavelengths Exhibit 05: Types of lasers and their treatment procedures Exhibit 06: Types of lasers used in medical segment Exhibit 07: Global semiconductor laser treatment market forecast 2015-2020 ($ billions) Exhibit 08: Five forces analysis Exhibit 09: Global semiconductor laser treatment market by application 2015 (% share) Exhibit 10: Global semiconductor laser treatment market by application 2015-2020 (% share) Exhibit 11: Global semiconductor laser treatment market by aesthetics segment 2015-2020 ($ billions) Exhibit 12: Global semiconductor laser treatment market by surgical segment 2015-2020 ($ millions) Exhibit 13: Types of laser treatment procedures used in glaucoma surgery Exhibit 14: Lasers used in medical laser devices in surgical segment Exhibit 15: General use of lasers in surgeries Exhibit 16: Global semiconductor laser treatment market by ophthalmic segment 2015-2020 ($ millions) Exhibit 17: Global semiconductor laser treatment market by dental segment 2015-2020 ($ millions) Exhibit 18: General uses of laser in dentistry Exhibit 19: Major types of laser-based dental treatments Exhibit 20: Sub-categories of dental laser treatment procedures Exhibit 21: Global semiconductor laser treatment market by geography 2015 and 2020 (% share) Exhibit 22: Global semiconductor laser treatment market by geography 2015-2020 (% share) Exhibit 23: Semiconductor laser treatment market in the Americas 2015-2020 ($ billions) Exhibit 24: Semiconductor laser treatment market in EMEA 2015-2020 ($ billions) Exhibit 25: Semiconductor laser treatment market in APAC 2015-2020 ($ millions) Exhibit 26: Laser-based aesthetic treatment procedures in major countries in 2014 (percentage of global aesthetic treatment procedures) Exhibit 27: Impact of drivers Exhibit 28: Impact of drivers and challenges Exhibit 29: Trend of global healthcare spending Exhibit 30: Healthcare spending of different regions Exhibit 31: Product segmentation Exhibit 32: Key products Exhibit 33: Topcon: Key product portfolio Exhibit 34: Other prominent vendors Exhibit 35: Global semiconductor laser treatment market snapshot 2016-2020 Exhibit 36: Geographical revenue growth rate in 2015
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