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Improving Lutein’s Efficacy with a Breakthrough Carocelle® Technology
There are many factors that can influence supplements' bioavailability, such as the type of ingredient and the format in which it is consumed and processed. The bioavailability of key substances in many food supplements can often be as low as 5-10% of what we ingest. Carocelle Micelle Technology has been developed to improve carotenoids bioavailability and bioactivity.
Does your supplement really work?
Bioavailability is the actual measure of what is detected in our systemic blood stream after you consume the ingredient. It can be only marked in clinical pharmacokinetics tests. Pharmacokinetics profile is routinely tested for all pharmaceuticals, unfortunately very few producers of dietary supplements actually do that. And it is simply impossible to develop a dietary supplement with proper, confirmed bioavailability without the pharmacokinetics tests. Most vitamins and supplements have not been tested for bioavailability and/or do not make this information available on their packaging. It is therefore impossible for a consumer to tell how much, if any, of a food supplement is being absorbed when they take it. The bioavailability of key substances in many food supplements can often be as low as 5-10% of what we ingest. High bioavailability is desirable as it means smaller doses can provide enhanced rates of absorption which are guaranteed when compared with untested, even higher dose supplements.
Cambridge Micelle Technology Inc. introduces Carocelle® Lutein & Zeaxanthin within a new range of supplements that have proven bioavailability data, giving consumers the confidence that the product is providing the intended level of supplementation.
Unique formulation of Carocelle® supplements
What is a micelle?
Micelles are structures formed naturally in the intestines to improve absorption of lipids and substances soluble in lipids (lipophilic). Micelles are formed spontaneously or during a dedicated chemical process and involve compounds that show a combination of fat-soluble (hydrophobic) and water-soluble (hydrophilic) properties. Their formation is necessary for proper absorption of fats and fat-soluble ingredients in our diet.
Carocelle® Technology was developed in Cambridge, UK. The technology is based on invention of vesicle-micelles formed from carotenoids, phospholipids and other cargo substances. This patent-pending technology replicates natural micellisation processes, that take place in our body, to improve active substances‘ bioavailability. Micellisation ensures that bioavailability is at its peak by protecting the active substance from destructive processes during digestion and increasing absorption on the way to the bloodstream.
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Unlike many supplements, Carocelle® has pharmacokinetic data for the finished product, not merely the raw ingredients. Understanding and determining the pharmacokinetic profile is critically important during the development process of dietary supplements as it leads to the optimization of absorption and bioavailability properties of the product. The efficacy of Carocelle® Lutein & Zeaxanthin has been proven in compliance with Good Clinical Practice in randomized, double-blind clinical trials.
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Carocelle Cambridge Micelle Technology™ was founded in 2015 in collaboration with UK biotech firm Lycotec, headed by Dr. Ivan Petyaev. The company invents proprietary formulations and products that are scientifically tested and proven in laboratories in Cambridge, UK. Carocelle Cambridge Micelle Technology™ has its headquarters in Cambridge and operates a network of partnerships with research and commercial partners around the world.
Dr. Ivan Mikhailovich Petyaev, MD, PHD
Dr. Petyaev is a medical doctor, researcher and author of scientific publications and inventions with applications in diagnostics, analytics, prevention and treatment of a variety of diseases. He spent his research years at MRS and Cambridge University in the Department of Pathology. To take his discoveries into innovative healthcare products he left University and set up his own company, Lycotec Limited. Dr. Petyaev has wide experience of driving his innovations through the product development phase, clinical validation and in the setting up of industrial production of the successful prototypes. His projects have been supported by Cambridge University, the MRC, Papworth and Addenbrooke’s Hospitals, the British Heart Foundation, the Department for Trade and Industry and the Eurostars Eurica Project.

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Do you love your smile? Do you smile big or are you guarded when you smile? You should have a smile you love to share! Often if we are not comfortable with the appearance of our teeth we choose not to laugh out loud or give that big smile when something makes us happy! Whitening could be a simple easy choice to give you the smile you are proud of.
There are whitening options that fit your lifestyle. You can choose from in-office whitening, done in about an hour or at-home whitening with results often in as little as seven days. In office whitening is a simple process that can, for some, whiten teeth up to eight shades whiter. Zoom! Whitening by Philips uses safe whitening gel and a whitening lamp, giving the most intense results by accelerating the ingredients to get to work. Not only do you get a whiter smile, your whitening experience includes post-treatment gel that’s clinically proven to reduce sensitivity and help protect enamel AND custom created whitening trays for at home maintenance! The at-home whitening process is accomplished with custom created whitening trays and multiple applications of whitening gel. The process success is up to you; follow the prescribed protocol and see results possibly in as few as seven days.
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With school starting it’s a good time to start boosting our immune systems and for me that also means stocking up on essential oils. As a “crunchy” mama I tend to gravitate towards the natural healing methods that help your body fight and boost your immunity rather than medicines that just mask symptoms. Here are some of my favorites to use during the school year to help us get through all those back to school sickies.
- Tea tree oil and peppermint– Household cleaning, in spray bottle for on the go disinfectant.
- Clove oil– applied to the gums for teething and loose tooth ouchies.
- Arnica- mixed with oil and applied topically for sore muscles and general achies.
- Lavender– in a spray bottle for on the go calm kid magic.
- Eucalyptus– in baths or mixed with Vaseline for home made vicks vap-o-rub for colds.
- Citronella and lemon grass– mixed with oil or in a spray bottle for natural bug repellent.
Recently I had a chance to test out some local Utah essential oils from the company Young Living. This is no small mom n pop anymore, this company is one of the leading essential oil companies in the world and has some of the most advanced technologies. Although this company has grown to be world known, they have not forgotten their Utah roots, their lavender is some of the most potent and delicious smelling oils and they use lavender from right here in Utah!
I was sent a box full of their most popular oils along with a Rose Home Diffuser. I heard people in my crunchy moms groups mention diffusers but I had no idea what one was. After the first use I wondered how I ever survived without one. This device mists out essential oil and water and fills a room with whatever scent you infused it with. I have been experimenting with the scents and doing research all week and came up with these 6 powerful combos for the most common back to school ailments.
- Colds, Sniffles and Coughs, for all of those back to school yucks: 4 drops of Eucalyptus, 3 drops of Peppermint, 2 drops of tea tree oil , 2 drops of Panaway
- Bravery, for the kiddos having a hard time being away from home: 3 drops of Valor, 2 drops of Purification
- Detox, to cleanse the house (and you) of all the rowdy school energy ( and germs!): 3 drops of Thieves, 2 drops of Purification
- Calm down, to help the kids get to bed at night: 3 drops of Peace & Calming, 3 drops of lavender
- Focus, help with focusing on homework: 3 drops of Brain Power, 2 drops of Magnify your Purpose
- Mood Booster, for perking up the kiddos when they wake up or reinvigorating them when they get home: 3 drops of Joy, 2 drops of Lemon
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This awesome set includes:
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Disclaimer: This information is for educational purposes only, and is not intended to prescribe, treat, prevent, or diagnose any disease or condition. The products in this post were gifted by the company, Young Living, however all opinions are my own.


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Resveratrol A to Z
Resveratrol is a type of polyphenol that can be found naturally in a variety of sources including grapes, Japanese knotweed (giant knotweed), berries, peanuts, dark chocolate and tea.
The French Paradox: Resveratrol, a compound found in red wine, first gained publicity in the early nineties when the CBS television show, 60-Minutes, investigated why people living in France, despite eating diets high in saturated fats, had lower rates of coronary heart disease than people living in the United States. The report concluded that a higher consumption of red wine may play a role in lowering coronary heart disease. Since then, researches have pointed to resveratrol, a substance contained in grape skins (and other plants such as Japanese knotweed), as the compound with the possibility of preventing or delaying coronary heart disease and many other health conditions.
What Should You Know Before Purchasing Resveratrol?
Its not surprising that consumers are confused about resveratrol products. Resveratrol is a general name for a product that is available in various purities: 5%, 10%, 20%, 50%, and 99%. In principle buying resveratrol is the same as buing gold. Gold is available in different purities and the law requires the dealer to clearly stamp the purity of the gold on the item (e.g. 5 , 9, 14 or 24 karat). If the resveratrol manufacturer does not indicate the purity on the label, then there is no way of knowing the amount of trans-resveratrol in the product, or if it has any health benefits at all. Resveratrol can provide great health benefits ONLY if it contains sufficient amounts of trans-resveratrol, the active ingredient and the beneficial substance in resveratrol. “resveratrol” does not mean Trans-resveratrol.
It is important to note that most resveratrol sold in USA and abroad is of a low purity (50% or less ). Since the FDA does not regulate the purity content labeling of dietary supplements, it is not surprising that manufacturers that offer low-purity resveratrol are doing it solely for monetary gain and therefore they do not disclose the purity content of the product. Instead, they use misleading descriptions such as “Extra Strength”, “Super Potency”, “High Purity”, “Pure Resveratrol” and other misleading statements. Remember, If the label does not clearly indicate the amount of trans-resveratrol, then there is no way of knowing its purity content, or if it even has any health benefits. It is important to note that 250-500 mg of trans-resveratrol is the minimum daily amount that is needed to promote the benefits of this product for healthy individuals, (higher dosage may be required for individuals with certain health conditions).
What is “Pure” Resveratrol?
“Pure Resveratrol” refers to a product that should contain contains only TRANS-RESVERATROL, the active ingredient and the beneficial substance in resveratrol. It is important to note that pure trans resveratrol does not cause any side effects compared to low purity products which contain emodin and other substances (part of the plant) that may cause gastrointestinal problems in sensitive individuals. As a reference, the physical appearance resveratrol made of Japanese-knotweed varies according to its purity and therefore may help distinguish between a high purity and low purity product. Pure resveratrol is white/off-white in color, and is odorless, while low purity resveratrol is brown and has a distinctive odor. The higher the purity is, the brighter the color will be. Resveratrol obtained from grapes is very expensive to produce and therefore is only available in low purity of 5-8 percent (trans-resveratrol content).
Trans-Resveratrol Vs Cis-Resveratrol
Both trans-resveratrol and CIS-resveratrol are found naturally in grapes, Japanese knotweed and other plants, however Trans-Resveratrol is the beneficial health substance in resveratrol products, while CIS form has no health benefits. High purity resveratrol contains high amount of trans-resveratrol, while lower purity products contain higher amount of CIS-resveratrol and lower amounts of trans-resveratrol.
Due to the purifying process low purity resveratrol cost about 40-60% less than pure trans-resveratrol.
Resveratrol 99% Vs Resveratrol 50%
Resveratrol-99 contains 99 percent of pure trans-resveratrol, the beneficial substance of resveratrol, while resveratrol-50 contains only 50 percent of trans-resveratrol. The other 50 percent contain ingredients that are a natural part of the plant but which have no health benefits. These ingredients include CIS-resveratrol and emodin, which may act as a laxative in some sensitive individuals. These ingredients account for the darker color and stronger odor of resveratrol- 50, as compared to resveratrol-99, which is white, has no odor, and has no side effects. Due to the purification process, resveratrol 50% typically costs about 40-50 percent less than resveratrol 99%.
Grape Resveratrol Vs. Japanese Knotweed Resveratrol
Most resveratrol sold in the USA and abroad is made of Japanese Knotweed. Resveratrol made of grapes is NOT superior to resveratrol made of Japanese knotweed, this is just a myth. Grapes resveratrol is only available in purities of up to 5%-8% trans-resveratrol compared to knotweed which is available in up to 99%-100% purity. Pure trans-resveratrol (99%) made of knotweed does not contain emodin and does not cause any side effects. Why the difference in purities? Its all in the cost. Unlike grapes, knotweed grows in the wild and contains higher concentration of trans-resveratrol. Prior to processing, knotweed can be stored in room temperature, while grapes need to be kept frozen. It takes about 250 kilograms of grape skins to produce 1 kilogram of resveratrol that yields only 5% trans-resveratrol product.
Beware of products that are labeled “made with grape resveratrol”. Most of those products are worthless. Usually, a minuscule amount (a few milligrams) of lowest purity grape resveratrol is added to a low purity knotweed resveratrol, a product which is low in price but also in effectiveness. Again, it’s another marketing gimmick to intentionally mislead consumers for the sole purpose of monetary gain while the product has no health benefit. Another product that may be confused with grape resveratrol (or resveratrol), is grape-seed, which does not contain resveratrol.
It’s clear that the source of resveratrol is not what matters, what is important is knowing the purity of the product you are purchasing. Remember, it’s the amount of trans-resveratrol that counts, not the source of the product.
Micronization is a process of reducing the size of a solid material. Some dietary supplements are water-soluble and therefore their absorption rate in the body is higher than the non water-soluble supplements. Since resveratrol is non water-soluble, the only way to increase its absorption and bio-availability rate is to reduce the size of the particle. The smaller the particle size the higher the absorption rate. Mega Resveratrol’s average particle size is 3 µm (0.003 mm), compared to 170 to 220 µm (0.17-0.22 mm) of standard resveratrol. Clinical studies have shown that micronized particle size increases the absorption rate by up to 210%.
Safety and Dosage
Resveratrol has been used for many years and no safety issues have ever been reported. During the last few years, a number of clinical studies confirmed that taking pure trans-resveratrol in dosages of up to 6,000 mg daily is safe and does not cause any side effects. Unlike pure trans-resveratrol, lower purity resveratrol may cause gastrointestinal side effects due to the content of emodin which may act as a laxative in sensitive individuals. Mega Resveratrol contains no emodin.
As a reference, the dosage used in the “Harvard Study” was equal to 23 mg per kg or about 500 mg per 50 pounds of body weight. For example: A person that weighs 150 pounds would take 1500 mg daily. This is just a suggestion based on the “Harvard Study”, not a rule.
Resveratrol may enhance the effect of blood thinning medications (i.e. Coumadin, Aspirin, etc.) and increase the risk of bleeding. Consult your health-care provider before taking resveratrol. Individuals with allergic reaction to grapes, red wine or polyphenols, are advised not to consume resveratrol.
Resveratrol Studies (Resveratrol Health Benefits)
Atherosclerosis (Hardening of the arteries)
Harvard Study-(PDF file)
About Mega Resveratrol 99% Trans-Resveratrol
Mega Resveratrol 99 is a pharmaceutical-grade supplement, micronized and purified to a minimum of 99% pure trans-resveratrol.
MegaResveratrol.com was a pioneer in introducing high potency resveratrol products and in setting the standards of voluntary third party independent lab testing for purity and safety.
We offer premium grade natural resveratrol supplements delivered in a vegetarian capsule and in powdered form at an economical price.
At Mega Resveratrol we are always trying to improve our products. For example, most dietary supplements and vitamins are made with “inactive ingredients”. These ingredients are added mainly to facilitate the manufacturing process but they have no health benefits. In some cases, these added ingredients may produce an allergic reaction or they even are unsafe. All of our resveratrol products are made with no excipient ingredients added. That means vegetarian capsules that contain pure resveratrol with absolutely no additives, binders, fillers or preservatives. (i.e. stearate acid, silica dioxide, etc.), just pure resveratrol.
Our natural resveratrol products are encapsulated in the USA in a GMP facility regulated by the FDA. Every batch is tested for purity by an independent U.S. laboratory. Please refer to the Certification Page.
Mega Resveratrol is a proud supplier of pure trans-resveratrol products to pharmacies and research institutions in USA and abroad. See the About Us page for details. Our customer’s reviews are independently posted and may be viewed at Google Reviews Page.
There is a difference between our company and most other companies and it’s not only in the quality of the product. It’s in the story behind the company and its foundation.
In 2003 I was lucky enough to walk out of a hospital alive after surviving a heart attack. I felt like a helpless “walking time bomb.” I knew it wasn’t a question of “if” but “when” my next heart attack would happen. I thought I had two choices – I could rely on miracles or on doctors and statins. Neither one prevented my first heart attack.
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That same year I had a routine “stress test” at the hospital. The cardiologist couldn’t understand how and why I performed so well until I described my use of resveratrol.
It’s been almost ten years since my heart attack, and I’ve never felt better. My cardiologist now takes resveratrol, and my company provides high quality resveratrol to satisfied consumers, health-care providers and research institutes in the USA and abroad.
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For years now, US citizens have been buying their prescription drugs online. An early adopter of the world wide web, and with some of the highest levels of uptake across all demographic groups, it is no wonder that older segments of US society buy prescription drugs online. Throughout the 1980s, 90’s and 00’s, prescription drug consumers increasingly realized the cost savings to be enjoyed from sourcing prescription drugs from Canadian pharmacies, and as the Internet picked up pace, so too did the choice of on line pharmacy organisations. Giants such as Canada Pharmacy emerged, a company that developed a vast number of websites, all aimed at US citizens sourcing cheaper branded and generic prescription drugs online.
In the USA, pharmaceutical imports have more than doubled in the past decade alone, according to the U.S Food and Drug Administration, and it estimates that 80 percent of ingredients in U.S-made drugs and 40 percent of finished medications Americans take come from abroad. But in recent months, the FDA has concentrated efforts on cracking down on online pharmacies selling prescription drugs, in particular Canadian pharmacies, the traditional lower-priced option for US consumers.
Late last year, the US Senate defeated an amendment that would have made it easier for Americans to buy prescription online from Canada for personal use. So, the FDA can continue to block such imports and there may well be a trend that sees the closure of more and more Canadian online pharmacies. Having been recently found to be supplying counterfeit Avastin, Canada Drug seems to be being used as an example of things to come as US officials ordered the company to stop marketing prescription drugs to American consumers through its 3,700 websites registered in a number of different countries. The decade-old Canada Drugs has prospered by filling millions of prescriptions for American customers with cheaper, price-controlled drugs from Canada and around the world. But the case of the fake Avastin has increased pressure to rein in and control cross-border pharmaceutical sales.
So as the USA continues to warn its public of the potential risks of buying prescription drugs online, the US recently launched “BESafeRx: Know Your Online Pharmacy” campaign; a national campaign to raise awareness about fake online pharmacies and the potential risk to consumer health. The FDA’s BeSafeRx follows research that identified that 1 in 4 consumers bought prescription drugs online. Of these, 30% said they were not confident about buying prescription drugs safely on the Internet. In addition, the National Association of Boards of Pharmacy analyzed more than 10,000 websites and found that 97% were not in compliance with U.S pharmacy laws and were actually listed as ‘Not Recommended”.
So how do US consumers source discounted prescription drugs online, but most importantly, safely? There are a few simple checks that consumers can undertake to confirm the legitimacy of an online pharmacy. For instance, if buying prescription drugs from the UK, the legitimacy of UK based online pharmacies can easily be confirmed as to whether or not they are regulated by the Medicines and Healthcare Products Regulatory Agency (MHRA), a government agency and part of the Department of Health, responsible for ensuring that medicines and medical devices work. In addition, reputable pharmacies will be verified and licensed by the General Pharmaceutical Council. The GPhC website (www.pharmacyregulation.org) is searchable, allowing consumers to verify pharmacy validity.
As the US FDA cracks down on online pharmacies, such as Canada Pharmacy, buying prescription drugs online at discounted rates outside of the US is not necessarily coming to a stand still. Instead, consumers sourcing prescription drugs need to adopt a higher level of diligence. They might consider UK based pharmacies and these can certainly be authenticated reliably using the aforementioned websites.
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