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Protein phosphatases have received great attention as drug-screening targets. MFP is a proprietary fluorogenic substrate for most phosphatases, i.e., alkaline phosphatases, acid phosphatases, protein tyrosine phosphatases, and serine/threonine phosphatases. The phosphatase-induced hydrolysis of MFP yields an intense fluorescent product that has excitation wavelength around 470 nm, and maximum emission around 510 nm. This characteristic makes the substrate adaptable to all the fluorescence instruments. SensoLyte® MFP Protein Phosphatase Assay Kit uses MFP to quantify protein phosphatase activities. The kit can be used for characterizing kinetics of enzyme reaction and high throughput screening of protein phosphatase inhibitors. The kit contains: - MFP phosphatase substrate - Protein phosphatase inhibitor - Assay buffer - A 'mix and read' assay protocol that is compatible with HTS liquid handling instruments.
Component A: MFP (1 vial), Ex/Em= 470 nm/510 nm upon phosphate group removal 1 mL
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Storage & stability
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Magnesium is one of the most popular food supplements, and the world is full of different magnesium products. What magnesium is needed for? How do you recognize a high-quality magnesium? How magnesium forms differ, and what effects do they have? What about timing – should you take magnesium in the morning or in the evening?
What is magnesium?
For humans, magnesium is one of the most important minerals. The human body contains 20-28 grams of magnesium, of which about half is bound to the bones, and the rest to the muscles, as well as other soft tissues. Magnesium is also the fourth most common mineral in our body.
What do I need magnesium for?
Our body uses magnesium for more than 300 different enzyme functions and numerous metabolic reactions. Among other things, humans need magnesium:
- For normal functioning of the nervous system, muscles and heart muscle.
- Magnesium also contributes to the normal health of the bones and teeth.
- To support normal electrolyte balance and energy metabolism.
- To fight fatigue and exhaustion.
- To contribute normal protein synthesis and to participate in cell division.
- To support normal psychological functions.
Where do I get magnesium from?
Magnesium can be found in several foods. Good sources of magnesium include whole grain products, avocados, green vegetables, beans, nuts and seeds. Magnesium is also obtained from drinks, for example coffee and mineral water. Dark chocolate is a source of magnesium too!
Can I get too little magnesium?
A serious lack of magnesium is quite rare if a person is healthy and has a varied diet. Magnesium deficiency can be caused by, for example, diuretic medication, long-time alcohol use, or diabetes if urine levels are high due to poor sugar balance. However, it is known that exercise increases the removal of magnesium from the body, which is why active people may need more magnesium than usual.
Signs of magnesium deficiency may include fatigue or muscle cramping and stiffness, poor muscle recovery, weakness, numbness, heart palpitations, and low blood sugar levels. If there is a lack of magnesium in the cells, it does not always show up in a blood test. That is why it can be tricky to notice deficiency.
Can I get too much magnesium?
The kidneys are involved in regulating the amount of magnesium in the body. If you get a lot of magnesium, excess magnesium will be removed from the body through the urine. Therefore, a healthy person cannot obtain too much magnesium from food or through oral magnesium food supplements. Exceptions include people with renal failure, as well as some elderly people.
What is the recommended daily dose of magnesium?
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When should I take my magnesium supplement?
You can take magnesium at any time of the day. However, it is recommended to take magnesium in the evening before going to bed, because it may help muscles and nervous system to relax and improve sleep quality. You can divide your daily magnesium dose and take half in the morning and half in the evening.
We recommend to take magnesium with meals. If you use an iron supplement and try to increase your iron levels, do not take magnesium and iron during the same meal, as magnesium may interfere with the absorption of iron.
Did you know this about different forms of magnesium?
The form of magnesium matters in terms of absorption. In food supplements, magnesium is bound to another substance, for example, citrate. The three most commonly used forms of magnesium are magnesium oxide, -citrate, and -bisglycinate.
The chelated forms of magnesium are highly absorbable. In these chelated forms magnesium is bound to some acid. For example, in magnesium bisglycinate, magnesium is bound to an amino acid glycine, with glycine in a ratio of 2:1 to magnesium. Some forms of magnesium may cause stomach problems in some people. For example, magnesium oxide needs acidity of stomach acids when absorbed and can irritate the stomach.
We recommend to read carefully the list of ingredients of the magnesium product. Generally speaking, forms of magnesium with -ate at the end of the name, are well absorbed. High-quality magnesium also contains as few additives as possible.
An optimal combination of three quality magnesiums
Aarja Health's Magnesium3 contains three highly absorbable forms of magnesium; magnesium citrate, -bisglycinate and -taurate. All these forms have their own special characteristics. Read below why we chose these forms of magnesium in particular.
Magnesium citrate is a compound of magnesium carbonate and citric acid, as well as one of the most absorbable forms of magnesium. Magnesium citrate is a very commonly used form of magnesium, and of the most studied chelated forms. It doesn't need stomach acids to be absorbed.
Magnesium bisglycinate is one of the most stomach-friendly forms of magnesium and is efficiently absorbed. Magnesium is bound to the amino acid (glycine), and the ratio of glycine to magnesium is 2:1. If your daily doses of magnesium are high, this form of magnesium is a great choice, since it does not irritate the stomach. Glycine has a calming effect, so this form is good to take in the evening, when it may improve the quality of sleep.
Magnesium taurate, like bisglycinate, is stomach-friendly and well absorbed. Magnesium is bound to an amino acid (taurine). Taurine increases the formation of the neurotransmitter GABA, a soothing and sleep-quality-enhancing neurotransmitter. Taurate is also considered a good form for cardiovascular health.
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In Australia and New Zealand 1 in 50 babies are allergic to cow’s milk and dairy products. Although most children out-grow cow’s milk allergy by the age of 4 years, persistent cow’s milk allergy may sometimes occur.
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Kitten nutrition tips : From weaning to adult
Both kittens and adult cats thrive on a balanced diet that changes to accommodate their age and life stage, though their individual nutrition needs can vary depending on the breed, age and size. Developing a healthy and nutritious diet was the foundation of our launch of Ocean Fish for cats, focused on growth, energy levels and overall health, felines at all stages of life will thrive on a balanced diet.
A balanced diet for kittens
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From birth to approximately 3 months
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If you are uncertain about possible sensitivity, always do a patch test before use or consult your healthcare professional.
If you develop skin or other sensitivity to any product,you should stop using it immediately and consult your physician.
Always read labels before using products. Body chemistry differs from one person to the other, effectiveness and reactions may differ. Visiting a physician before using new products is highly recommended. If symptoms occur discontinue use and consult your doctor.
Disclaimer: We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. Content is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional.
Any products you purchase through our store should be used as directed on the product container or packaging. As everyone has different skin, body, and health conditions that may react to an allergen at any given time, any product could cause negative skin reactions or react differently to various treatments.
Actual results may vary. We are not responsible if such a reaction should occur as a result of any consumer using our products
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With the groundbreaking innovations emerging these days in the medical field, the iPhone has proven worthy once again. This was achieved by taking over the roles of portable medical devices that are handy and much-needed by the patients on a regular basis. On numerous occasions, this phone has empowered, enhanced, and changed the way people think of phones these days. Furthermore, this is achieved by connecting the medical devices through its optic or computing power to the smartphone itself. Some of these innovations are worth discussing here:
The iPhone Is the Diabetic’s Best Friend
Patients with diabetes have no option but to measure their blood glucose levels often with some sort of glucose meter. Such a meter requires a blood specimen on a band of special glucose paper, and it can then be measured by the glucose meter. A small attachment just like a card reader has become available that has gotten a nod from both Sanofi and the Food and Drug Administration (FDA)–it is Sanofi’s iBGStar.
As a Vital Signs Monitor
Another plug-in known as Withings Blood Pressure monitor is easily attached to the phone via a peripheral blood pressure cuff, and the phone converts into a master control device to take as well as record blood pressure. According to the manufacturer, this portable blood pressure device shows compatibility with other smart devices as well, such as the iPod Touch and iPad. Such a portable device is really handy and beneficial for high blood pressure patients, as well as those individuals living in old homes, as they can monitor their blood pressures in a timely fashion.
As a Plug-in for ECG Device
With the FDA approval of a new ECG device called AliveCor, the phone converts into an ECG/EKG (electrocardiogram) recorder. After the device is plugged into the iPhone, it can record and analyze a patient’s heart rate with an affiliated app.
As a Portable Ultrasound
A device called the Mobisante’s MobiUS SP1 ultrasound system is available on the market these days. This innovative device attached to the phone via an app can deliver with the same precision and accuracy as any other ultrasound technology out there. The phone, therefore, becomes a display screen for visualization and record keeping purposes.
SPIROMETER and BREATHALYZER Attachments for iPhone
The app SpiroSmart iPhone developed at the University of Washington Medical Center precisely measures and estimates lung air volume. The app functions on the principle of making an algorithm with the audio part of an expiration. Research studies have found that there is only a 5 percent difference, in comparison to the good old spirometer for lung function tests.
Finally, the take way here is that these innovative devices and apps represent only the tip of the iceberg for the clinical applications of the iPhone and other such smartphones.
By Ambereen Ahmed
Edited By Leigh Haugh
Wired–Apple Turns the iPhone Into Medical Research Device With ResearchKit
Internet Medicine–Top Ten Medical Uses of the iPhone
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BOSTON – Health 2.0 will unveil 10 of what it bills as "the hottest new companies in healthcare technology" at the Launch! session during Health 2.0 Spring Fling Matchpoint in Boston, May 14-15.
Since its introduction in 2008, Launch! has given more than 55 new and innovative companies a platform for debuting new technologies. Launch! has introduced companies such as Unity Medical, Remedy Ventures, TheCarrot, Univita, Basis and the WSJ's 2010 top startup company, Castlight Health.[See also: Competition seeks care transition, adverse events apps]
Each of the 10 companies will present at Launch! in a series of rapid-fire, back-to-back, four-minute demos. The audience will determine which company gets invited to demo on the main stage during the 6th Annual Health 2.0 Fall Conference in San Francisco.
The companies making their debut are:Cobalt Therapeutics – Colbalt Therapeutics has a portfolio of online cognitive behavioral health programs designed to ease the integration of behavioral health into primary care while lowering costs. CEO, Seth Feuerstein, will show the patient experience through Cobalt's online portal.HealthSouk – HealthSouk CEO,Neilesh Patel and COO Neal Reiter will show how patients can use HealthSouk's website to perform a detailed search for healthcare services, prices and ratings, as well as a look at how physicians may set available times, prices and confirm appointments.Kinergy Health – Kinergy Health COO Neil Agatewill debut MyKinergy, which provides management and communication putting the patients and their caregivers at the center of a secure, private network with healthcare managers, facilities, and other family members.RealMealz – RealMealz founder and CEO Connie Kwan has created a Web and mobile application focused on teaching new and occasional cooks the skills, recipes and ingredients needed to make healthy and delicious meals.BetterDoctor – BetterDoctor co-founder and CEO Ari Tulla will demo the BetterDoctor web application, which helps users find the best doctor for them using detailed search criteria. Users can search by specialty, insurance plan, ratings and schedule their appointment online.function Medicine – function Medicine COO,Jochen Talmon has taken a physical exam to the next level by creating a wellness program based on weekly baseline health assessments. With an interactive dashboard, users are provided a real-time image of their current status and an easy way to communicate with the function Medicine medical team.Novi Medicine – Novi Medicine founder Joshua Spanogle has developed a web-based platform that allows dermatologists to diagnose and treat skin conditions over the Internet. Users can submit a form in just 15 minutes, ensuring a quick and private experience.Thryve – Thryve CEO Caleb Oller launches the mobile food coach, Thryve, to help users build a happier and healthier life. For users with food sensitivities, or anyone hoping to become more in tune with their diet, Thryve makes it easy for users to track their food intake and how they feel, giving them insight into their body's reaction to certain foods.eTherapi – eTherapi CEO Farzad Soleimani showcases an online behavioral health portal that connects those seeking to improve their mental and emotional wellbeing with licensed therapists in a live video-chat format. Soleimani will demo the process of scheduling an appointment and getting connected with a provider.onPulse – onPulse founder Corey Booker will demonstrate the secure, online environment that empowers individual health care providers and patients to easily communicate and create connected health teams. Booker will show how the activity of each health unit is measured and how the actionable data is presented, leading to better health outcomes.
"Launch! is a unique platform for new technologies," said Indu Subaiya, Health 2.0 co-chairman and CEO. "We're giving start-ups front row exposure to forward-thinking health care leaders, major companies, and investors – providing innovators with both the opportunity and marketplace to control their own destiny."


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Here you are, mid-forties, a little bit frazzled, a little bit irritable and somewhere in between the ‘can’t be bothereds’ and the bloating, you decide to go to your local medico for some advice. Somehow your body is changing; it doesn’t feel the same, it doesn’t look the same, and it certainly doesn’t behave the way it used to.
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If you were born with a high hairline, your hair is thinning and exposing your forehead, your hair is receding at the temples, or you suffer from traction alopecia, you are not alone. Dr. Harris performs state-of-the-art hairline transplants for women at the Hair Sciences Center. You have come to the right place.
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How does Dr. Harris address thinning hair in women?
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Before deciding if a hair transplant is right for you, Dr. Harris will also evaluate whether you are a good candidate for non-surgical hair restoration therapies for women. In particular, platelet rich plasma therapy can be an effective treatment for thinning hair and temple recession.
Dr. Harris is an internationally recognized, award-winning physician specializing in hairline restoration. He is renowned for his ability to blend science and art to create extremely natural, undetectable hairline restoration results for his patients. In fact, it is this attention to detail and artistry that sets him apart.
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Q: As a doctor, what kind of mask would you suggest people wear, given that there are so many in the market?
Ans: This is the most important point when we talk of protection and prevention of Covid and it seems that this aspect got lost somewhere while managing the active infection of Covid. The masks available in the market are of many types such as cloth/fabric masks (which are single layered, double layered, triple layered), surgical masks, N95, N99 and respirator masks.
The selection of masks depends on the area where the mask is worn. For example, in hospitals the N95, N99 in Covid areas and good quality surgical masks in non-Covid areas provide adequate protection and these masks are not recommended for general public. For the general public, a three-layered mask as per guidelines of WHO and CDC are most suitable.
Q: Many use one-time use disposable masks. Are these safe in the current scenario?
Ans: If the quality of the disposable mask is good, and the three layers are incorporated, it offers good protection from droplet infection both ways, i.e., spray from cough or sneeze of the person wearing it, and droplets from others entering through the mask and infecting the person. The protection of surgical masks is far superior than cotton masks.
Q: What about cotton masks? For economical purposes many opt for washable and reusable masks. What’s your take on such masks?
Ans: For the general public who are moving about in public places and not in hospitals or infected areas, fabric/cotton masks are good enough, some of which may be even homemade and can be washed and reused. But most pertinent is the method of preparing of the fabric mask. The fabric masks, which the common man is nowadays wearing, are available everywhere — on the roadside, outside the stations, and in many other public places costing Rs 10-20.
But these masks are not made as per recommendations wherein three layers of fabric should be used and should be immediately banned. As regards protection, these masks probably do not offer more than 1% particle filtration.
The right way of manufacturing masks is to have the inner layer of absorbent material such as cotton, middle layer of non-woven non-absorbent material, such as polypropylene and then an outer layer of non-absorbent material like polyester or polyester blend. Densely woven cotton fabrics, such as quilting cotton, can also be used to provide at least 50-60% particle filtration.
While the government and health authorities are extremely tied up with so many major issues related to Covid, the least we can do is take responsibility of our own selves and our near and dear ones by following mask guidelines and not purchase masks indiscriminately without assuring that it actually provides protection.
In other words, though masks alone may not be enough in providing complete protection, they do play a very vital role and should not be taken lightly and should not be worn only as a show-off or to prevent fine by the police.
Q: What about kids, what kind of masks should they wear?
Ans: Kids are generally unable to follow the guidelines of wearing masks. They keep touching it, taking it off from the face, and do not carry out hand hygiene protocols as stringently. So, unless the guidelines of wearing masks are followed, any type of mask becomes ineffective. For older children, the guidelines are the same as adults.
Q: When it comes to hygiene, what’s the best way to dispose off a used mask?
Ans: The steps of disposing off a used mask are:
A: Wash/sanitise hands.
B: Hold the mask from behind the ears and pull it away from the face.
C: For disposable mask, do not put it directly in the bin. Wrap it in a bag and seal it before throwing in the bin and wash/sanitise hands again.
D: Wash the face with soap and water after completing the process of disposing of mask.
Q: And washable cotton masks, what’s the best way to clean them up?
Ans: For washable mask, follow the steps of removal from the face as mentioned above and then directly soak it in soap solution and wash/sanitise hands again. Drying these masks in the sun gives additional clearing up of coronavirus as UV rays affect the virus, though there is no conclusive evidence in the literature. This is the simplest, yet effective, way to clean up cotton masks.
Q: If there’s a Covid positive patient at home, should the family members mask up as well?
Ans: The protection of other family members when there is a Covid positive patient at home is most essential and thus, wearing appropriate mask (preferably surgical or N95 mask) is recommended especially for the older and younger members of the family.
Q: What about Asthma patients or the ones with breathing difficulties, is wearing masks advisable for them? If yes, what kinds should they opt for? If no, what alternative can they look at?
Ans: Asthma patients are more prone to severe form of Covid infection, and are at high risk. Thus, wearing masks is more important for these patients. Studies have shown that wearing masks does not worsen the asthma and it is safe to wear masks without drop in oxygen saturation. Those who have breathing difficulty and are uncomfortable wearing masks, should not travel in public places or attend social gatherings where wearing mask is mandatory.
Q: Is wearing two or more masks at a time an appropriate action?
Ans: Yes, wearing two masks or double masking is the latest recommendation by CDC and Dr Anthony Fauci, America’s leading infectious disease expert. However, there are certain guidelines of which two masks can be worn together and must be adhered to. Pairing is recommended with one surgical mask with one cloth mask. Any other pairing such as double surgical mask, double cloth mask, or N95 with any other mask is not recommended.
Q: What are the common mistakes people should avoid when it comes to wearing and selecting masks.
Ans: The common mistakes, which are hampering the protection offered by masks are multiple. First of all, selection of mask as mentioned above, and then proper technique of wearing mask (mask should properly fit the nose and mouth, not be loose, washing of hands before wearing the mask and sanitising after wearing mask if mask is used one), not touching or lowering the mask repeatedly, sanitising hands if mask is touched, proper removal of masks as described above and then finally, washing the mask as soon as it is wet or soiled or everyday even if it is not soiled are very important aspects for adequate and appropriate protection from Covid.


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What is Face Oil and Why Do You Need It? If you haven’t heard of face oil before, it may be just what your skin needs to look and feel healthier! Face oils are used to restore dry, dehydrated and flakey skin. Depending on the blend of oils, they can soothe redness, resist microbial skin-overgrowth […]
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Tucked away in the leafy suburb of Waterkloof, the Lifestyle Centre is dedicated to women’s personal care, health and well-being. The Centre offers a much-needed alternative to the hustle and bustle of shopping malls by providing a comfortable and peaceful setting.
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The first signs of facial aging for women appear in their 20s with fine lines around the eyes. Skin in their 30s and 40s+ continually and gradually displays loss of firmness and elasticity becoming thin, lax, and uneven.
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Patient Financing Options
At our practice, we understand that the cost of even the most basic dental care may be prohibitive for some of our patients. However, we believe that no patient should have to forgo dental treatment because cost is a concern. We offer convenient financing and payment options so that even the most advanced dentistry treatments are within the reach of each of our patients. We also make it a point to fully inform patients of the cost of treatment before we begin a procedure, so patients will never suffer "sticker shock" when they receive their bill.
For patients wishing to extend payment for their dental investment over a period of time, we offer Springstone Patient Financing for up to 84 months of low interest payments.Feel free to visit each of these websites for more information regarding interest and monthly payment options.
We accept most insurances and are in-network preferred providers of Delta Dental Premiere plans, Delta Dental PPO plans, and United Concordia Elite plans. We want all of our patients to obtain the maximum benefit from their insurance coverage.
Your insurance can be a helpful supplement towards your dental investment. Depending on your plan benefits and options, you may have additional out-of-pocket expenses. As a courtesy to our patients who have insurance coverage, we will file all your claims on your behalf to ensure you receive the benefits you deserve. In return, we ask that you pay your dental copay at the time of services rendered.


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