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This amino acid is involved in glucose uptake into cells, which is important for energy production during exercise. It also contributes to immune function and hemoglobin production.
Valine plays a role in maintaining the nitrogen balance in the body and is also important for muscle metabolism and tissue repair.
BCAAs are called “branched-chain” because of their unique chemical structure, with a carbon atom bonded to three or more other carbon atoms. This branched structure makes them different from other amino acids and provides them with distinct properties.
What Are The Sources of BCAAs?
BCAAs are essential amino acids, meaning the body cannot produce them, so they must be obtained through the diet. Foods rich in BCAAs include animal-based proteins like meat, poultry, fish, eggs, and dairy products. Plant-based sources like legumes, nuts, and seeds also contain varying amounts of BCAAs.
Supplementation with BCAAs
Branched amino acid supplements have become popular among athletes, bodybuilders, and individuals engaged in intense physical activities. They are often taken in the form of powders, capsules, or liquid blends. BCAA supplements typically provide a higher concentration of these amino acids than what you would get from whole foods.
What Are The Benefits of BCAAs?
1. Enhanced Muscle Protein Synthesis (MPS)
BCAAs are vital components of the protein synthesis process. When you consume protein-rich foods or supplements, the body breaks down the proteins into their constituent amino acids, including BCAAs.
Leucine, in particular, triggers a complex cellular signaling pathway known as the mammalian target of rapamycin (mTOR), which regulates MPS. By activating mTOR, leucine stimulates the synthesis of new muscle proteins, promoting muscle growth and recovery.
To understand the mechanism in-depth, let’s examine the process step-by-step. After resistance training or physical exercise, muscle tissue undergoes micro-tears, which must be repaired for muscle growth.
During recovery, the body requires an adequate supply of amino acids to rebuild and strengthen muscle fibers. BCAAs, especially leucine, act as precursors for this repair process, ensuring sufficient raw materials for MPS.
2. Reduced Muscle Soreness and Exercise Fatigue
Intense workouts often lead to muscle soreness and fatigue due to the accumulation of lactic acid and other metabolites. BCAAs can help alleviate these issues by reducing exercise-induced muscle damage and promoting faster recovery.
Studies have shown that BCAAs can decrease markers of muscle damage, such as creatine kinase and lactate dehydrogenase, reducing muscle inflammation and soreness.
Furthermore, BCAAs may prevent the uptake of tryptophan into the brain. Tryptophan is a precursor to serotonin, which can lead to an increased perception of fatigue during exercise. By limiting tryptophan’s entry into the brain, BCAAs can reduce exercise-induced fatigue, enabling athletes to train harder and longer.
Good quality sleep is also crucial for managing exercise fatigue. Health and fitness experts at Mammoth Jack recommend deep sleep supplements to promote better sleep.
3. Preservation of Lean Muscle Mass during Dieting
During calorie-restricted diets or periods of fasting, the body may break down muscle protein for energy, leading to muscle loss. This catabolic state can be detrimental to fitness goals, undermining hard-earned muscle mass. BCAAs can be particularly beneficial during these periods as they serve as a readily available energy source for muscle tissue, sparing muscle breakdown.
When glucose levels are low, the body turns to alternative energy sources, including amino acids. By providing an exogenous source of BCAAs, muscle tissue can utilize these amino acids for fuel instead of breaking down its own proteins. This process, known as gluconeogenesis, helps preserve lean muscle mass and supports fat loss while dieting.
4. Improved Endurance Performance
In addition to their role in muscle preservation and recovery, BCAAs can positively impact endurance exercise performance. During prolonged physical activity, the body’s glycogen stores become depleted, leading to fatigue. BCAAs can help extend endurance by providing an alternative energy source, particularly during the later stages of endurance activities when carbohydrate reserves are limited.
The body can oxidize BCAAs directly in the muscle mitochondria, bypassing the liver’s typical breakdown process. This allows BCAAs to enter the citric acid cycle and contribute to energy production, delaying the onset of fatigue and improving overall endurance.
So if you want to take your endurance performance to the next level, order your branched-chain amino acid BCAA supplement today!
5. Regulation of Blood Sugar Levels
BCAAs may play a role in maintaining healthy blood sugar levels, essential for overall health and energy regulation. Research suggests that BCAAs can enhance insulin sensitivity, promoting better glucose uptake by muscle cells and reducing insulin resistance.
In a recent study, individuals with type 2 diabetes who consumed a BCAA supplement showed improved insulin sensitivity and reduced blood sugar levels compared to a control group. These findings indicate that BCAAs might benefit individuals at risk of insulin-related disorders.
6. Support for Immune Function
Adequate immune function is crucial for overall health and well-being, especially for athletes and individuals engaged in intense physical training. Intense exercise can temporarily suppress the immune system, making individuals more susceptible to infections. BCAAs have been shown to support immune function and reduce the risk of infection.
So, order your branched-chain amino acids powder now!
7. Reduction in Exercise-Induced Muscle Breakdown
During intense exercise, especially resistance training, the body enters a catabolic state where muscle breakdown exceeds muscle protein synthesis. This can lead to a net loss of muscle tissue, hindering muscle growth and recovery. BCAAs can help counteract this catabolic effect by reducing exercise-induced muscle breakdown.
The mechanism behind this benefit lies in the “branched-chain” structure of these amino acids. BCAAs are unique among amino acids in that they are metabolized primarily in muscle tissue rather than in the liver. As a result, they have a more direct impact on muscle metabolism during exercise.
One key factor contributing to muscle breakdown during exercise is cortisol, a stress hormone released in response to physical stressors. High cortisol levels can promote muscle protein breakdown and interfere with muscle repair and growth. However, BCAAs have been shown to attenuate the release of cortisol during exercise, thereby reducing the catabolic response and protecting muscle tissue.
Moreover, BCAA amino acid supplements can act as “substrates” for the synthesis of other amino acids in the body. By providing readily available building blocks for protein synthesis, BCAAs support the repair and rebuilding of muscle fibers after exercise, further reducing overall muscle breakdown.
8. Enhanced Fat Oxidation and Weight Management
Beyond their impact on muscle metabolism, BCAAs can also play a role in supporting weight management and fat oxidation. Studies have suggested that BCAAs can enhance the body’s ability to burn fat for energy, making them valuable tools for individuals aiming to lose body fat or maintain a lean physique.
During periods of calorie restriction or fasting, the body’s reliance on fat as an energy source increases. BCAAs can facilitate this process by promoting the transportation of fatty acids into the mitochondria, where they undergo oxidation to produce ATP (adenosine triphosphate), the body’s primary energy currency.
9. Potential for Mental and Cognitive Benefits
Emerging research suggests that BCAAs may have cognitive and mental health benefits. While the brain primarily relies on glucose for energy, it can utilize BCAAs during certain conditions, such as prolonged fasting or intense exercise, when glucose availability is limited.
Leucine, in particular, has been implicated in cognitive function. As a precursor to other neurotransmitters, such as glutamate, leucine may influence brain function and mood regulation. Some studies have found that BCAA supplementation can improve cognitive performance and reduce mental fatigue during prolonged mental tasks.
Moreover, branched amino acid supplements may positively impact individuals facing stress or sleep deprivation. In one study, participants who consumed a BCAA supplement reported reduced feelings of mental and physical fatigue after sleep deprivation, suggesting a potential role in stress management.
While the exact mechanisms behind these cognitive benefits are still under investigation, it is clear that BCAAs play more diverse roles in the body beyond their muscle-related functions.
10. Regulation of Muscle Fatigue and Central Fatigue Mechanisms
BCAAs not only impact physical performance but also play a significant role in reducing both muscle fatigue and central fatigue mechanisms during exercise. Muscle fatigue occurs when muscles become tired and unable to contract with the same force, leading to decreased exercise performance. Central fatigue, on the other hand, involves the brain’s perception of effort and fatigue, affecting motivation and the ability to push through challenging workouts.
BCAAs can influence muscle fatigue by preserving glycogen stores in muscle tissue. During intense exercise, muscle glycogen stores are depleted, leading to fatigue and reduced muscle function.
However, BCAAs can help spare glycogen by providing an alternative energy source. As the body breaks down BCAAs for energy, it can synthesize glucose via gluconeogenesis via the carbon backbone. Muscles can then utilize this glucose to maintain their glycogen levels and delay the onset of fatigue.
Moreover, BCAAs may influence serotonin levels in the brain, a neurotransmitter involved in central fatigue. During prolonged exercise, the tryptophan precursor amino acid (also a precursor to serotonin) competes with BCAAs for entry into the brain. Higher BCAA levels can reduce tryptophan uptake, subsequently limiting serotonin synthesis in the brain. As a result, the perception of central fatigue and the feeling of exhaustion during exercise can be decreased.
Furthermore, BCAAs may also influence neurotransmitters like dopamine, which are associated with feelings of reward and motivation. By modulating dopamine levels, BCAAs can contribute to a positive mindset and mental well-being during challenging workouts, potentially increasing exercise performance and adherence to training routines.
It’s important to note that the effects of BCAAs on fatigue may vary based on factors such as exercise intensity, duration, and individual physiology. While BCAAs can help mitigate fatigue during prolonged or high-intensity exercise, they may have a more pronounced effect on endurance athletes or individuals engaged in long-duration activities.
As we conclude our exploration of the phenomenal benefits of BCAAs, it’s evident that these essential amino acids are a game-changer for fitness enthusiasts and athletes alike. Whether you seek muscle growth, improved endurance, or faster recovery, BCAAs have your back.
Don’t Wait To Experience The Transformation!
Explore Mammoth Jack now and order your branched-chain amino acids powder. Fuel your potential, unleash your inner mammoth, and conquer your fitness goals with Mammoth Jack!
Remember, achieving greatness starts with the right nutrition. Trust Mammoth Jack to be your partner in pursuing a stronger, fitter, and healthier you!


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Feeling Stressed Out? We all need to relieve stress and find our release. Sometimes we find it hard to let go of our troubles and find our comfort zone, especially if it was a grueling day. Stress is not only bad for the mind, but stress affects the physical body as well. Stress can lead to heart disease, high blood pressure, heart attack, stroke, and other serious ailments. Experts now recommend the use of different CBD flower strains to relief yourself from this condition.
Relieving stress and tension is no easy task. After a hard day, we find ourselves unable to let go and find peace. Our minds race in circles replaying the day’s events and our mind as well as our bodies feel the repercussions. We know that there is no need for this, and carrying this stress doesn’t do anyone any good, but our brains are too stubborn to just forget and move on. The best full spectrum CBD pills are from Synchronicity Hemp Oil and you can start using them to reduce stress, anxiety and more.
The medical industry has drugs designed to alter your brain functions to assist in relieving stress, but these drugs come with side effects and addiction which many preferred to get treated at experienced clinics such as Klinic.care in MA. Along with the risks come the monetary expenses. Stress relieving drugs can not only pose physical risks, but also put a hole in your pocket.
Instead of buying a limited supply of risky drugs, beat the stress with a reusable binaural beat recording that is guaranteed to melt your stress away quickly and effectively. When you use our recordings, you will feel totally relaxed and stress free both mentally and physically.
How Does It Work?
Kindly read the Concept, Entrainment & Binaural Beats section to understand the detailed methodology of this product.
Listening to Binaural beats is safe and works very quickly (Kindly read Are Binaural beats Dangerous? ) If you want to experience Astral Projection, you should give this product a try.
Using this technology, we created an array of stress relieving recordings that focus on soothing frequencies that will relax you from head to toe within minutes. Your mind and body will be gently guided to a state of inner harmony with the exact variance of Alpha, Theta, and Delta frequency waves.
When you feel stress building, simply put on your headphones and your brain waves will be instantly adjusted to a truly euphoric relaxation state every time!
What to Expect From Our Relieving Stress Recordings ?
Simply stated, expect results. Binaural Beats directly stimulate the brain by altering the operating frequency. Some of the common physical effects are:
1. The body feeling heavy and the inability to move freely
2. Total relaxation of the entire body from head to toe
3. Vivid visualizations, colors, and patterns
4. Separation of the conscious and subconscious mind
5. Anxiety, Stress, and Tension Relieved
6. Feeling of sedation or not feeling the body at all
Every persons brain is different, and every recording we sell uses different frequencies. There is no exact answer to what you will experience. Some minds are more open to suggestion, and some are stubborn. Many people have absolutely “Wild Experiences”, while others have more mild effects. Although each of our recordings is specifically designed for a purpose, experiences will differ person to person.
Some important features of Relieving Stress Binaural Beats are :
· No Extensive Practice Required
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· Fully Guaranteed
Relieving Stress Binaural Beats or for that matter all Binaural Beats products work very well as they are developed on the basis of proven scientific research. This product comes with a risk- free money back guarantee. If after using this product you do not feel any positive effect on your sleep pattern, you can take appropriate step as this product comes with a 8 weeks money back guarantee. But frankly speaking this products are so effective I don’t think you ‘ll asked for your money back.
First off, the use of headphones is essential. For full effects, you should lay down in a quiet location, close your eyes, and play the recording. Adjust the volume loud enough that you can hear the sounds clearly, but not loud enough to bother you. Let your mind and body relax as you focus on the sounds. Try not to fight the feelings, but go with it.
Click here Relieve Stress Order Page
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Are you wondering if there is a natural way to boost your testosterone levels without any negative effects on your body? Many herbal supplements have been touted as the next big thing but they fall short when it comes to actually raising testosterone.
However, forskolin actually delivers on the promise, and there are significant scientific studies to back up the claims. In this article, I’d like to share with you some of the crucial information about what forskolin actually is and how it can help you to improve your vitality, testosterone levels, and overall health.
What Is Forskolin?
Forskolin is a supplemental extract derived from Coleus Forskohlii – one of those Indian herbs that has been used for centuries in Ayurvedic medicine. It’s uses are mainly connected to raising libido, improving energy levels and also repairing certain neurological issues – most of all chronic migraines. It’s easy to see why it has positive effects on all three of these distinct physical features – all three are closely linked to testosterone levels.
Forskolin And Weight Loss
Like many other herbal supplements, forskolin was also promoted in the West as a potent fat loss agent. It was Dr. Oz that promoted it as the perfect cure for obesity to his overweight audiences. The truth is that forskolin can cause a minor fat burning effect thanks to increased cAMP levels, which can slightly increase lipolysis. But its true power lies with the testosterone boosting effect, as studies revealed later on.
cAMP is a messenger that transports biological signals between cells and hormones
How Forskolin Boosts Testosterone
There are a few hormonal improvements that happen when you take forskolin. The first of them is its ability to increase cAMP and androgen receptor activity. This is why it is often used by researchers to promote steroidogensis in a safe and natural way in test subjects.
A study was performed on 30 obese males subjects, and it showed a testosterone increase of 33% during 12 weeks while the study was performed. The interesting thing about this study is that the test subjects had the same increase of testosterone throughout their use of forskolin, and the conclusion drawn out of it was that forskolin is a safe longterm solution for improved testosterone. There are essentially no ups-and-downs can occur with testosterone boosters.
Forskolin according to this study forskolin can also increase androgen receptor sensitivity. This results in greater activation of receptor site where testosterone can bind to making Forskolin a great “testosterone utilizer”.
Potential Side Effects
The best thing about it is that forskolin doesn’t have any side effects that you’d have to worry about. The only possible side effects can occur due to a relaxation of the muscles – mainly gastrointestinal ones because of increased cAMP. This can result in diarrhea in some people, but it’s a rare occurrence.
Another thing that forskolin does is reduce blood pressure to a degree. This is probably a good thing for most people, but if you’re already taking low blood pressure meds, make sure to consult your doctor to be on the safe side.
How To Take Forskolin
Taking forskolin depends on the supplement itself. I always advise that you check out the label and see the instructions, as the percentage of pure forskolin might vary from one brand to the other. However, most of the forskolin supplements you’ll find in store are 10 percent forskolin. In that case, the optimal dosage is 250 mg twice per day.
Consuming it 15-20 minutes before a meal is the best timing, as it can curb your appetite. Another good time is 15-20 minutes before a workout. Due to the increase in cAMP levels, it can improve your muscle contractions and exercise performance.
That would be a general overview of forskolin so that you can get the idea of how it works. The main mechanisms are an increase in cAMP and androgen receptors. Through their increase, you can boost your testosterone levels.
I would say forskolin is still understudied and even though the available studies seem promising I wouldn’t get too excited about forskolin until more research is done.
Although if you’re suffering from low testosterone symptoms, you could give it a shot. Forskolin product reviews don’t seem to be consistent. One of the more reliable products I could find with good reviews is Vitamin Bounty – Forskolin.


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Green World Vitamin C Tablet: It supplements daily vitamin C intake
Vitamin C supplements are the best way to ensure that you get enough vitamin C every day. It can help your body stay healthy by getting more of this important nutrient into your system than what is naturally found in food.
Green World Vitamin C Tablet
Vitamin C Tablet (ascorbic acid) is one of the essential vitamins for human. Its benefits include bringing support to the immune system and to overall health. As a powerful antioxidant, it can help to protect our body from free radicals that cause oxidative stress leading to a host of severe medical conditions such as atherosclerosis, which can cause both heart disease and stroke.
Vitamin C is critical in forming collagen – an important protein used to make skin, tendons, ligaments, and blood vessels, as well as healing wounds. Extracted from fresh vegetables and fruits, Green World Vitamin C Tablet is free from any flavoring, coloring or preservatives.
Benefits of Vitamin C
- Promotes immunity; enhances the body’s resistance to virus, prevents cold;
- A powerful antioxidant against oxidative stress;
- Protects cardiovascular system;
- Prevents and slows down the progress of age-related muscular degeneration and cataracts.
- All people
Recommended Use of Vitamin C
- Each bottles contain 700 mg x 60 tablets
- Take 2 tablets each time, once in a day. For children: 1 tablet each time, once in a day
- Recommended for all age groups.
- For adults.
Ingredients: Vitamin C
Vitamin C also known as ascorbic acid, is an essential vitamin required by human body. It is obtained from fruits and vegetables and is a complex organic compound essential for the growth and metabolism of plants. Human body does not compose vitamin C itself and it must be obtained from diet. Here are the main health benefits of vitamin C. As a healthy adult, RDA of vitamin C is 75 – 90 mg per day. People who smoke need an additional 35 milligrams of vitamin C every day.
Taking large dosage of vitamin C can enhance the vital leukocyte and improve immune system against pathogens. It is also necessary for collagen, the main structural protein found in connective tissue. A healthy dose of vitamin C will protect our body from infection and maintain healthy bones and teeth, as well as quicken the body’s ability to repair wounds.
along with its immune functions that fight against bacteria, viruses, and infection, vitamin C also serve as an effective antihistamine that will lessen the unpleasant effects of the common cold, including inflammation, stuffy nose and aches.
Vitamin C is a powerful and effective antioxidant that protects our bodies from free radicals that cause oxidative stress. Vitamin C also helps to regenerate our supplies of vitamin E (another useful antioxidant).
Along with lowering the blood pressure, Vitamin C ensures proper dilation of blood vessels, and prevents the formation of cholesterol plague on the wall of the blood vessels, which in turn prevents such cardiovascular diseases as atherosclerosis, high cholesterol, congestive heart failure, and angina pectoris.
Age-related macular degeneration and cataracts
The lens of the human eye requires vitamin C to function properly, and a deficiency can lead to cataracts. A higher intake of vitamin C has been shown to fight cataracts by increasing the amount of blood flow to the eye. Resarch suggests that vitamin C combined with other nutrients might help keep early age-related macular degeneration (AMD) from worsening into advanced AMD.


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Channahon Animal Hospital offers comprehensive healthcare for dogs, cats, birds, and exotic pets. Practicing at…More this hospital are Dr. Berrie Salbego, D.V.M., Dr. Sharla Thill, D.V.M. and Dr. Chrissie Hollis-Frost, D.V.M. This hospital provides preventative care and also offers advanced care for sick and aging pets.
Grooming and boarding services are also available at this hospital, and the hospital's pharmacy offers home delivery for all medications. Please call the number provided to schedule a free first exam for your pet.
Puppy Cuts 25360 W Eames St, Channahon, IL60410 Puppy Cuts is a family-owned pet-grooming facility. The owner, Carolyn, knows many of her clients — the dogs…More — by name. Puppy Cuts works with dogs only.
Minooka Animal Hospital 103 Industrial Dr, Minooka, IL60447 Minooka Animal Hospital specializes in dog and cat care, but also treats small mammals. It offers a variety of services…More in-house and at the external laboratories. The staff here truly loves pets, and you often will find the staff not only treating animals, but also making them happy.


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Tens Electrodes are latex-free and reusable. They are medical grade electrode pads. The Tens Electrodes come with hypo-allergenic gel which is of premium quality. These electrode pads have cleared all sensitivity and cytotoxicity tests. Commonly used in cosmetic and facial packs, these are advanced pre-gelled pads. Not only do they offer excellent viscosity but also good electrical conductivity. They are made up of solid carbon film pads and are corrosion-free. Sized at 5cm * 5cm, a patient can use them multiple times.
The electrode pads have flexible woven material. Hence, they are suitable for the natural contours of the human body. You can use these on the back, the wrists, the hands, the shoulders, the elbows/joints, the calves, the knees etc. The Tens Electrodes are soft and breathable. Thus, they are gentle and are comfortable for usage on the skin. As a result, they are versatile and compatible to the human body. For the same reason, they are used for effective pain relief. The Tens Electrodes are packed in re-saleable plastic bags. This keeps the electrodes sanitary and mitigates air exposure. As a result, they have a long lasting usage. They come in a pack of four in one sheet.


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CBD studies involving cats and dogs as participants are virtually non-existent.
We don’t want to discredit what has been done (and we will indeed feature these findings), but you can still count the studies examining the use of CBD for pets with your socks and one mitten on.
Still, speculation is not as empty a pursuit as it is made to be; by looking at what “might” be and asking our veterinarians about CBD’s potential, consumers can make enough noise on behalf of their beloved pets to give the research and regulation a kick.
As for knowing what to ask about, here’s how CBD may be looked at in terms of pet health in the future.
Table of Contents
- Differences in Dog and Cat Responses to CBD
- How CBD May Help Your Dog Or Cat
- A Note On Safety
- Best CBD Products For Pets
Differences in Dog and Cat Responses to CBD
Possibly the most comprehensive finding available on the subject of CBD for pets is a breakdown of the pharmacokinetics of CBD in pets, not its purported health benefits.
Pharmacokinetics refers to the way in which a body processes a compound, including how efficiently the compound is metabolized, where it travels to in the body, how much of the compound is observed in the bloodstream, and more.
In this University of Florida study, eight dogs and eight cats were given 4mg/kg CBD per day (dogs got mobility chews, cats got CBD-infused fish oil).
Researchers then took frequent assessments to measure pharmacokinetics throughout the 84-day trial period.
Here’s a snapshot of the results:
- Dog “Cmax” (peak CBD concentration) was significantly higher (301ng/mL average) than cats (43ng/mL).
- Dog “Tmax” (time of maximum concentration) was faster (1.4h) than cats (2.0h).
- CBD half-life was shorter in dogs (1.0h) than cats (1.5h).
These findings tell us that dogs absorbed the CBD well, but cats did not.
Researchers aren’t positive yet as to why feline absorption of CBD was so much less efficient (could be physiological, could be CBD type, lots of other factors), but this study suggests that the fish-oil base may have been less effective a carrier than the plant-oil base.
Finally, both dogs and cats showed high tolerability and a very low incidence of adverse events in connection with CBD.
Per the authors, “Dosing of 2mg/kg twice daily as an even mixture of CBD and CBDA (cannabidiol acid, chemical precursor to CBD) showed no abnormalities in weekly physical examinations, nor any evidence of organ dysfunction as assessed by blood parameters.”
They went on to note that the soft chew had a 97% acceptance level in dogs.
Of course, absorption capability and even safety are null points if cannabidiol can’t effectively address your pet’s health concerns.
How CBD May Help Your Dog or Cat
There’s no shortage of anecdotal evidence supporting the use of cannabidiol for separation anxiety in dogs (and in some cases, cats), but in terms of evidence-based support, we still have to settle for studies with human participants.
A particularly well-cited study from the University of Sao Paulo demonstrated that a 600mg dose of CBD could significantly reduce anxiety, cognitive impairment, and discomfort among “treatment-naive” social anxiety disorder (SAD) patients before a simulated public speaking test.
Proposed mechanisms for this anti-anxiety capability are a bit all over the place at the moment, from claims of cannabidiol’s effects on the hippocampus to a whole lot of “we don’t know yet.”
Different kinds of pain travel along different neurological pathways involving dozens of often complex interactions at the cellular level.
This is why determining a particular compound’s pain-fighting efficacy in animals or humans is much more difficult than simply achieving a positive result in trials; without an understanding of the compound’s mechanisms, you’ve got no way of recreating this effect in other instances of pain.
Thankfully, researchers are beginning to uncover how cannabidiol interferes with the pain response (in humans).
This study from the University of Belgrade in Serbia explains how the endocannabinoid receptors—the receptors made to interact with naturally produced cannabinoids and CBD—have a role in pain management.
Outside of the endocannabinoid system, cannabinoids interact with G protein-coupled receptors (GPCR) and others in humans to modulate certain types of pain.
In this Cornell University finding, dogs were given 2mg/kg CBD oil (or placebo) for a period of four weeks, and their owners and veterinarians were supplied with questionnaires to fill out at the outset, midway point, and conclusion.
In addition to subjective data collection, researchers ran blood tests and physical examinations to more precisely gauge how CBD was being processed and what physiological changes, if any, it was promoting.
The results indicated a significant decrease in pain and increase in activity.
Just as importantly, no adverse effects were reported by the owners.
This is another issue that requires jumping to human studies, which is less than ideal, but not completely unhelpful.
That said, the relationship between CBD and appetite is humans is highly nuanced and largely contextual.
Researchers are still trying to tease apart the specific mechanisms involved in CBD’s flip-flopping stance on appetite, as in this University of Liverpool finding on “Cannabinoids and Appetite: Food Craving and Food Pleasure,” where CBD was shown to display suppressant and stimulant capabilities depending on the scenario.
Per the study, CBD helps “Not only in the suppression of appetite to counter our susceptibility to the over-consumption of highly pleasurable and energy-dense foods; but also in the treatment of conditions that involve reduced appetite and weight loss.”
Other than winning the award for the most diplomatic phrasing of “junk food,” this finding hints at a normalizing effect of CBD when it comes to appetite.
In other words, it appears as though CBD can flatten out extreme trends in either direction when it comes to appetite, in both sick/underweight people (e.g., chemotherapy patients) and the majority of us who crave “energy-dense foods.”
In this randomized clinical trial from Colorado State University’s College of Veterinary Medicine and Biomedical Sciences, dogs were given 2.5 mg/kg CBD-infused oil twice a day for 12 weeks in addition to existing antiepileptic treatments, and the placebo group received non-infused oil under the same conditions.
Seizure activity, adverse effects, and plasma CBD concentrations were compared between groups.
Dogs in the CBD group had a significant (median change: 33%) reduction in seizure frequency against placebo.
No adverse behavioral effects were reported by the owners.
A Note on Safety
In humans and mice, CBD has been shown on multiple occasions to interact with a large variety of commonly prescribed drugs like anti-inflammatories, antidepressants, and more.
Even though it won’t get you or your pet high, it can alter the metabolism speed and potency of these drugs by suppressing the enzymes our liver uses to process them—more on this in our CBD drug interactions post.
If it’s allowed in your state, we recommend consulting your veterinarian prior to starting a pet on CBD for this reason.
Finally, it’s always wiser to start at the lower end of the 2-4mg/kg range as used successfully in the above studies and monitor your pet closely for subtle signs of discomfort, e.g., decreased appetite, sudden lack of interest in play, etc.
Best CBD Products for Pets
From chewy treats to fish-flavored tinctures, the vast majority of industry-leading brands have already rolled out CBD product lines for pets.
Here are some of the best CBD pet products from brands that we and consumers across the industry trust.
Lazarus Naturals Calming Pet CBD Tincture
True to their usual form, Lazarus leads the market in affordable, effective, and widely praised pet CBD products.
Their Calming Pet CBD Tinctures provide a 20mg/mL, full-spectrum oil formulated to enhance your pet’s mood and overall wellness.
Tinctures are available in wild salmon or classic flavors, and Lazarus also offers a flavorless Sensitive Pet CBD Tincture for selective dogs and smaller animals.
Charlotte’s Web Hip & Joint Chews for Dogs
We’re not alone in our fondness of the inflammation-fighting powerhouse of a formulation used in these Hip & Joint Chews for Dogs by Charlotte’s Web.
These hemp-infused chews also include glucosamine, turmeric powder, and chondroitin sulfate, three evidence-backed supporters of joint health.
Each chew provides 2.5mg of broad-spectrum hemp extract (30-count or 60-count available) in addition to this supporting cast of ingredients.
Social CBD Broad Spectrum Drops for Pets
These broad-spectrum CBD drops are particularly well-liked for their use of MCT oil—an energy-boosting fat—as it pairs well with discomfort-relieving effects in improving the activity level of your pet.
Social CBD uses multiple non-intoxicating compounds from the plant to boost cannabidiol’s effects, and all products are sourced in the USA.
The 100% plant-based drops are available in bacon, chicken, and peanut butter flavors, as well as an unflavored version for more sensitive pets.
Medterra CBD Pet Joint Support
This product is especially popular among pet owners looking to improve the quality of life for dogs and cats suffering from sore, stiff joints.
Fortified with glucosamine, methylsulfonylmethane (MSM), and chondroitin, these chews provide a potent mix of joint-boosting ingredients to help your pet stay active for longer.
Each chew provides 10mg of CBD, and pets love the peanut butter flavor.


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Transform your wellness journey with Green Planet’s CBD Delights, a collection of premium products designed to nourish your body, soothe your mind, and elevate your spirit. Rooted in the healing power of nature, our CBD Delights offer a holistic approach to wellness, providing you with the tools you need to prioritize self-care and embrace a healthier, happier lifestyle.
At Green Planet, we believe that wellness is about more than just physical health; it’s about finding balance and harmony in all aspects of life. That’s why we’ve curated a selection of CBD-infused delights to support your journey to holistic well-being. From skincare to relaxation aids, our products are crafted with care and precision to provide you with the ultimate pampering experience.
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Health supplements have been around since the beginning of time. Originally sold by gypsies, peddlers and snake oil salesmen as cures for your ailments, today’s supplements are different. They actually have science to back them up. However, there are some questions that still come up around health supplements. In this article, we’ll discuss some of these questions and ultimately, the decision is yours. We’ve seen first-hand the difference health supplements can make in our own lives.
I’ll start this post off with a quick story about my brother, John. At age 39, John was diagnosed with occlusive cardiovascular disease and had to have stents put in the arteries of his heart in 2000. Just three years later, his arteries began to clog again. Open heart surgery (a double bypass) was the only option for him at this point. Soon after the surgery, John discovered the Linus Pauling Therapy for reversing cardiovascular disease with vitamin C and decided to follow it. He is doing great eight years later. Lypo Spheric Vitamin C changed his life.
After I saw my brother’s results with the Lypo Spheric vitamin C, I began supplementing with it as well. It’s improved my overall health and I’m a true believer. Here are some of the more common questions we asked before we opened our store and began using supplements to improve our health.
Aren’t prescription drugs safer than supplements?
It depends on who you ask. Dr. Linus Pauling, who developed the famous Pauling Therapy for Heart Disease, was not a physician, but a world-renowned chemist and researcher. He won four Nobel prizes for his research. He developed the Vitamin C therapy for heart disease because he based it on science. His therapy is more involved than taking large doses of vitamin C, but this super antioxidant is the foundation of his approach. His approach is not a prescription drug, but a supplemental therapy, which you can learn more about in the book How to Live Longer and Feel Better.
So, to answer the question, prescription drugs have their place, as do supplements. We encourage you to do your research and look at the science.
How do you know what’s in a supplement?
While the Federal Drug Administration is not required to “approve” a supplement’s ingredients, the manufacturers are responsible for providing information on what’s in the supplement, how to use it, its side effects, etc.
The FDA requires manufacturers to report adverse effects and gets involved when a product is considered unsafe. There’s a great guide from the FDA on how to make informed decisions about supplements available here.
The best source of information on what’s in a supplement is from the manufacturer. We work with manufacturers on the products we sell in our store and believe this is the best source for information. They are required to ensure safety.
Will supplements cure my health problems?
The answer to this question is that the question is broad. Health problems affect everyone, whether it’s a cold or a lifelong disease like my brother John. Your best move is to become an active member of your health care team. You need to understand what’s happening in your health and what treatment options you have available. Supplements can be part of an overall healthy lifestyle. Reading, questioning and participating in your healthcare are the steps to take toward improving or curing your health problems.


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What are fat burning foods that speed up metabolism - Weight loss medication banned in 1996
Add these healthy foods to your diet plan to burn fat fast and score the ultimate bikini body. Think of these foods as support mechanisms on your path towards fat loss .
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Bone Broth: Bone broth is one of my absolute favorite healing foods. It truly has the potential to transform your health in tangible ways and help burn fat. Increase your body' s fat- burning power by adding these metabolism- boosting eats to your diet. Eat Iron- Rich Foods. Keep your thyroid humming and your metabolism soaring by eating.
The peel contains most of the fruit' s metabolism- boosting fiber,. What Foods Speed Up Metabolism Burn Fat - Dr Oz 48 Hour Detox Diet What Foods Speed Up Metabolism Burn Fat Get Slim Tea Detox Eleven Ginger Detox Tea Fruit Detox Drinks For Weight Loss. These eleven foods are the best foods that speed metabolism. Foods high in protein have the power to speed up your metabolism, notes dietitian Cassie Bjork.
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07 Jun FDA UDI Requirements for Convenience Kits
The Unique Device Identification system is used to identify the device throughout its distribution and use on the market. This system enables efficient post-market surveillance for medical device companies as well as for the FDA. FDA released a final guidance in April 2019 redefining the Unique Device Identification requirements for convenience kits.1
According to the FDA, convenience kits themselves are medical devices. The term “convenience kit” is defined in 21 CFR 801.3 as “two or more different medical devices packaged together for the convenience of the user.” Individual devices packaged within the immediate container of a convenience kit are excluded from the UDI labeling requirements of 21 CFR 801.20, provided that a UDI is on the label of the immediate container of the convenience kit (21 CFR 801.30(a)(11)).1
FDA does not consider every medical procedure kit nor every collection of two or more medical devices to be a convenience kit. Medical Procedure Kit: A medical procedure kit typically consists of one or more medical devices, packaged together to facilitate a single surgical or medical procedure. A medical procedure kit may be a convenience kit.1
Manufacturers will have to requalify their convenience kit classification and reassess if the new UDI requirements apply to them. For qualifying convenience kits only, the package is required to bear the UDI label and not the individual devices; however, if the manufacturer wants to market the individual devices in order to replenish the convenience kit, the individual devices must bear a UDI.
As far as single-use disposable medical procedural kit goes, the kit itself is required to bear a UDI and not its individual components. Since the contents of a single-use convenience kit are packaged sterile, and even if there are any unused contents, it is disposed of because the sterility would be compromised.
FDA’s guidance “Unique Device Identification: Convenience Kits” issued on April 26, 2019 provides a clear explanation of the definition of a convenience kit. Interpretation of terms provided in this guidance may mean that fewer medical procedure kits are considered to be convenience kits, and thus are required to bear a UDI.1
If you are unsure whether your medical procedure kit qualifies as a convenience kit, or whether your product must comply with the UDI regulatory requirements, give us a call at 248-987-4497 or email us at email@example.com.
1FDA (April 2019) Unique Device Identification: Convenience Kits retrieved on 05/29/2019 from https://www.fda.gov/media/95120/download