A variant has been detected on Chromosome 6 in LOC121740638, TFAP2A, TFAP2A-AS2 (BRD4-independent group 4 enhancer GRCh37_chr6:10403277-10404476| transcription factor AP-2 alpha| TFAP2A antisense RNA 2). What is its effect — pathogenic or benign? If pathogenic, name the disease.
Pathogenic; Branchiooculofacial syndrome