Given a variant located on Chromosome 3 and affecting LOC107303340, VHL (3p25 von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase Alu-mediated recombination region| von Hippel-Lindau tumor suppressor), assess whether it is benign or pathogenic. Indicate the associated disease if pathogenic.
Pathogenic; Nonpapillary renal cell carcinoma