The gene GAREM2, HADHA (GRB2 associated regulator of MAPK1 subtype 2| hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha) on Chromosome 2 contains a mutation. Based on this information, is the variant pathogenic or benign? Provide the disease if relevant.
Pathogenic; Mitochondrial trifunctional protein deficiency