A genomic change on Chromosome 19 affects LOC130064475, LTBP4 (ATAC-STARR-seq lymphoblastoid silent region 10639| latent transforming growth factor beta binding protein 4). Classify this variant as benign or pathogenic, and name the disease if relevant.
Pathogenic; Cutis laxa with severe pulmonary, gastrointestinal and urinary anomalies