The following genetic variant occurs in LOC126859690, PKHD1 (MED14-independent group 3 enhancer GRCh37_chr6:51888848-51890047| PKHD1 ciliary IPT domain containing fibrocystin/polyductin) on Chromosome 6. Classify its clinical effect — pathogenic or benign — and list any associated condition.
Pathogenic; Autosomal recessive polycystic kidney disease