Chromosome 9 houses a mutation in gene DYNC2I2, LOC126860772 (dynein 2 intermediate chain 2| CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:131396972-131398171). Classify its clinical impact — is it pathogenic or benign, and what disease does it lead to if any?
Pathogenic; Short-rib thoracic dysplasia 11 with or without polydactyly