| patient_id,age_at_dx_yrs,sex,race_ethnicity,geographic_region,socioeconomic_status,hemophilia_type,severity_class,factor_activity_pct,mutation_type,inhibitor_high_risk_mutation,prophylaxis_flag,prophylaxis_type,factor_product_type,factor_dose_iu_kg,factor_frequency,factor_trough_iu_dl,factor_halflife_hr,factor_adherence_pct,factor_annual_iu,factor_cost_usd_yr,home_infusion_flag,port_access_flag,prophylaxis_start_age_months,emicizumab_flag,emicizumab_regimen,emicizumab_abr_reduction,fitusiran_flag,marstacimab_flag,concizumab_flag,inhibitor_flag,inhibitor_titer_bu_ml,inhibitor_class,inhibitor_onset_exposure_days,inhibitor_high_risk_mutation_flag,iti_flag,iti_protocol,iti_success_flag,iti_duration_months,bypassing_agent,inhibitor_thrombosis_flag,abr_annual,joint_bleed_rate_annual,target_joint_flag,target_joint_count,cns_bleed_flag,gi_bleed_flag,psoas_hematoma_flag,bleed_hospitalization_flag,isth_bat_score,hjhs_score_annual,wfh_bleeding_score,synovitis_grade,pettersson_score,mri_joint_score,cartilage_loss_flag,osteophyte_flag,joint_space_loss_pct,hemosiderin_flag,subchondral_cyst_flag,ankle_rom_deg,knee_rom_deg,elbow_rom_deg,joint_replacement_flag,joint_replacement_age_yrs,gait_impairment_flag,aptt_seconds,vwf_antigen_iu_dl,factor_recovery_iu_dl_per_iu_kg,peak_thrombin_nm,etp_nm_min,d_dimer_ug_ml,crp_mg_l,il6_pg_ml,hiv_positive,hcv_positive,hbsag_positive,gene_therapy_flag,gt_product,gt_vector_dose_vg_kg,gt_factor_expr_yr1_pct,gt_factor_expr_yr2_pct,gt_factor_expr_yr5_pct,gt_abr_reduction,gt_zero_bleed_flag,gt_liver_enzyme_flag,gt_immunosuppression_flag,gt_nab_flag,gt_expression_loss_flag,gt_response,mortality_flag,mortality_cause,hospitalization_flag,hospitalization_days_yr,qol_sf36_pcs,promis_pain_interference,haem_a_qol,phq9,gad7,work_days_missed_yr,employment_status,catastrophic_bleeds_lifetime |
| HC003-0000001,4.81,Male,White_non_Hispanic,Europe,Low,B,Severe,0.1,Other,0,1,Tertiary,Plasma_derived,37.2,Every_other_day,15.2,9.5,0.554,146560,64664,1,0,17.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,3,0.5,15.2,None,7.9,1.0,0,0,12.8,0,0,30.6,119.2,145.0,0,N/A,0,66.4,140.6,3.08,130.6,856.1,0.472,5.41,9.84,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,19.7,59.6,77.5,8,2,2,Employed_part,1 |
| HC003-0000002,4.67,Male,Black_non_Hispanic,US,Low,A,Severe,0.1,Large_deletion,1,0,None_on_demand,Recombinant_EHL,21.3,Every_other_day,15.7,21.4,0.291,180855,103803,1,0,15.5,1,Monthly,0.929,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,1,0,15,40.9,11.9,Mild,46.5,12.5,0,0,46.8,0,1,34.3,140.0,145.0,1,38.4,1,102.8,56.8,2.57,146.6,774.9,0.398,15.73,2.89,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Surgical_complication,0,0,30.3,46.6,73.6,9,13,9,Employed_full,2 |
| HC003-0000003,4.77,Male,White_non_Hispanic,Latin_America,Middle,A,Mild,29.63,Missense,0,0,None_on_demand,Recombinant_EHL,36.6,3x_week,20.2,21.5,0.671,860772,113602,0,0,10.1,1,Biweekly,0.874,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,1,7,9.7,9.9,None,20.3,2.0,0,0,68.4,1,0,42.6,102.3,122.5,1,36.7,0,31.7,115.1,2.78,172.6,649.4,0.305,7.82,1.89,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,27.9,51.1,72.2,12,4,1,Employed_full,0 |
| HC003-0000004,0.56,Male,Hispanic,US,Low,A,Severe,0.1,Large_deletion,1,1,Tertiary,Recombinant_EHL,42.8,Every_other_day,11.4,24.0,0.761,177138,142723,1,0,1.0,0,N/A,0.0,0,1,0,1,2.4,Low_titer,17,1,0,N/A,0,0,Emicizumab_bypass,0,6,4,0,0,0,0,0,1,26,0.0,21.8,Mild,31.2,7.2,1,0,41.8,0,0,30.8,140.0,145.0,0,N/A,0,76.0,32.0,2.0,99.1,992.1,0.227,5.74,1.8,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,HIV_AIDS,1,12,39.5,61.2,36.1,15,9,14,Employed_full,1 |
| HC003-0000005,0.17,Male,Hispanic,US,Middle,A,Mild,39.66,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,25.9,Weekly_EHL,1.0,14.5,0.704,65293,419347,1,0,31.9,1,Biweekly,0.974,0,0,1,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,5,41.9,15.6,Moderate,37.7,1.8,0,0,19.4,0,0,45.2,110.8,124.9,0,N/A,1,61.9,92.9,2.52,86.2,643.7,0.423,3.49,48.17,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,22.0,56.3,63.6,6,8,16,Employed_full,2 |
| HC003-0000006,2.91,Male,White_non_Hispanic,Europe,Low,A,Mild,13.49,Intron22_inversion,1,0,None_on_demand,Plasma_derived,28.3,Weekly_EHL,12.3,8.2,0.431,497873,157405,0,0,22.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,0,12,6.3,13.0,Moderate,63.6,1.0,0,1,10.1,0,0,37.7,102.2,115.2,0,N/A,0,60.1,113.4,1.75,126.2,904.5,0.322,2.34,3.51,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,0,0,34.8,49.0,74.0,1,3,5,Employed_full,1 |
| HC003-0000007,2.82,Male,Other,Latin_America,Middle,A,Mild,14.6,Small_indel,0,0,None_on_demand,Recombinant_EHL,23.8,Biweekly_EHL,13.2,17.4,0.54,660202,165415,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,29,22,0,0,0,0,0,0,32,0.0,13.3,Moderate,27.3,14.6,1,0,43.8,0,0,49.9,88.5,119.9,0,N/A,0,31.4,120.0,2.47,60.8,869.8,1.659,3.58,7.84,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,61.2,69.0,80.8,11,6,2,Employed_part,4 |
| HC003-0000008,6.25,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Small_indel,0,0,None_on_demand,Recombinant_SHL,25.2,Weekly_EHL,5.8,8.0,0.789,726163,232031,1,0,23.7,0,N/A,0.0,0,1,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,36,27,0,0,0,1,0,1,14,1.1,18.8,None,0.0,17.6,0,1,17.0,0,1,42.8,140.0,127.7,0,N/A,0,26.4,97.0,1.93,56.4,857.1,0.698,9.62,11.17,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,3,39.2,47.5,59.1,13,2,3,Disability,1 |
| HC003-0000009,0.16,Male,White_non_Hispanic,US,Middle,B,Mild,33.47,Missense,0,0,None_on_demand,Recombinant_SHL,41.7,Every_other_day,12.9,8.0,0.648,500323,159746,0,0,12.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,26,20,0,0,0,1,0,0,9,16.7,6.5,Mild,39.4,15.6,0,1,20.2,0,0,63.0,137.8,110.9,0,N/A,0,72.5,93.2,4.0,80.3,707.8,0.176,6.49,7.25,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.5,26.1,80.2,13,12,2,Disability,0 |
| HC003-0000010,2.09,Male,Hispanic,US,Middle,A,Mild,10.61,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,20.0,Every_other_day,9.8,17.4,0.631,551784,219713,0,0,13.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,13,10,0,0,0,0,0,0,14,15.5,5.0,Mild,25.4,0.0,1,0,50.8,0,1,43.5,105.4,115.7,0,N/A,1,37.1,115.9,2.7,93.6,671.0,0.118,9.46,6.43,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.2,56.9,66.3,9,2,10,Employed_full,0 |
| HC003-0000011,0.14,Male,Asian,Other,Low,A,Severe,0.1,Small_indel,0,1,Primary,Plasma_derived,20.5,Every_other_day,3.9,18.0,0.693,276997,206966,0,0,8.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,1,12,5.0,10.1,Mild,0.0,0.0,0,0,61.1,1,0,27.4,125.9,99.0,0,N/A,0,87.4,126.6,3.07,12.3,650.9,0.219,4.88,6.3,0,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.3,57.3,25.8,17,7,13,Employed_full,0 |
| HC003-0000012,2.18,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Plasma_derived,40.9,Biweekly_EHL,16.0,12.3,0.685,77205,191242,0,0,24.4,1,Monthly,0.688,0,0,0,1,8.4,High_titer,10,0,0,N/A,0,0,rFVIIa,0,1,1,0,0,0,0,0,0,2,9.2,2.6,Severe,4.0,19.9,0,1,29.2,0,0,39.4,117.5,110.2,0,N/A,0,42.7,138.6,2.28,137.7,803.0,0.127,2.18,11.38,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.2,56.6,60.6,6,4,6,Disability,0 |
| HC003-0000013,3.46,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Non_factor,33.0,Biweekly_EHL,8.6,14.6,0.66,272864,717288,0,0,8.4,0,N/A,0.0,0,0,0,1,11.0,High_titer,17,1,1,Low_dose,1,29,aPCC,0,3,2,0,0,0,0,0,0,6,15.6,11.6,None,38.2,6.5,1,1,30.3,0,0,42.3,107.9,129.2,0,N/A,0,77.1,63.9,2.6,104.6,507.9,0.209,11.34,2.9,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,8,38.2,60.0,50.2,15,2,4,Employed_part,0 |
| HC003-0000014,0.77,Male,Asian,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_EHL,45.0,3x_week,9.6,14.8,0.843,389626,283669,1,0,4.8,1,Monthly,0.895,0,0,0,1,21.5,High_titer,33,1,0,N/A,0,0,rFVIIa,0,3,2,0,0,0,0,0,1,10,30.9,12.8,None,8.5,0.0,1,0,36.4,0,0,31.1,134.3,143.8,0,N/A,0,52.3,94.4,2.85,126.9,602.7,0.139,10.55,4.97,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.0,50.4,53.4,1,10,12,Employed_full,0 |
| HC003-0000015,2.46,Male,Black_non_Hispanic,Europe,Low,A,Mild,28.12,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,24.4,3x_week,9.2,14.9,0.606,247419,104730,0,0,31.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,16,12,0,0,0,0,0,0,6,19.0,11.4,None,0.0,14.5,1,1,75.6,0,0,60.2,102.5,141.5,0,N/A,0,51.3,38.6,1.86,32.2,950.1,0.232,5.2,0.93,0,1,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,23.6,66.3,76.7,0,4,7,Employed_full,1 |
| HC003-0000016,0.31,Male,Other,Asia_Pacific,Low,A,Moderate,3.13,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,29.0,3x_week,19.4,10.5,0.701,240746,216449,1,0,15.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,15,11,1,1,0,0,0,0,17,8.2,9.1,Mild,0.0,8.4,0,1,18.6,1,0,38.3,71.2,132.7,0,N/A,0,44.9,61.7,2.06,68.4,762.2,0.234,6.99,1.38,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,52.9,42.3,66.2,1,0,7,Disability,0 |
| HC003-0000017,0.18,Male,Hispanic,Latin_America,Low,A,Moderate,3.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,22.7,Every_other_day,11.8,12.7,0.668,150472,121071,0,1,16.2,1,Monthly,0.794,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,17,12.3,25.2,None,47.6,11.4,0,0,32.8,1,0,34.3,120.2,97.5,0,N/A,1,74.6,80.3,2.89,66.4,821.7,0.339,6.69,2.3,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,30.3,55.8,54.7,4,8,10,Employed_full,0 |
| HC003-0000018,0.63,Male,Hispanic,Latin_America,Middle,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_SHL,29.1,Biweekly_EHL,12.5,12.0,0.867,147113,224836,1,0,26.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,7,5,0,0,0,0,0,0,4,24.2,19.5,None,12.9,0.0,0,0,17.6,1,0,44.2,116.3,109.5,1,49.5,1,80.7,124.2,2.29,86.9,430.2,0.255,3.08,15.93,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,57.6,49.7,52.5,7,3,7,Employed_full,7 |
| HC003-0000019,1.8,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,13.8,Every_other_day,9.4,10.3,0.723,808462,90437,1,0,10.0,0,N/A,0.0,0,0,0,1,37.4,High_titer,19,1,0,N/A,0,0,aPCC,0,5,4,0,0,0,0,1,0,18,35.2,11.2,None,20.1,6.0,0,0,31.3,1,0,31.1,103.1,121.4,1,68.6,0,58.1,86.5,2.03,93.7,572.2,0.146,3.64,5.78,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,16,31.6,66.1,68.1,2,7,6,Disability,0 |
| HC003-0000020,0.83,Male,Other,Europe,High,B,Severe,0.1,Nonsense,0,1,Primary,Plasma_derived,33.5,3x_week,14.8,10.4,0.815,826213,103374,1,0,12.4,0,N/A,0.0,1,0,1,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,6,1.7,12.7,Mild,18.3,13.7,0,1,3.6,0,0,53.6,97.2,142.3,0,N/A,0,78.0,91.9,2.08,129.8,710.1,0.796,2.16,13.84,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,25.1,48.1,59.4,8,9,6,Unemployed,1 |
| HC003-0000021,2.49,Female,White_non_Hispanic,Europe,Middle,B,Mild,31.43,Splice_site,0,0,None_on_demand,Recombinant_EHL,30.6,3x_week,20.1,22.5,0.84,267911,213620,0,0,21.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,34,26,1,1,0,0,0,0,6,28.4,23.0,Moderate,25.9,4.2,1,0,35.1,0,0,51.2,83.8,115.0,0,N/A,1,65.3,108.4,1.79,99.0,642.5,0.416,3.63,10.45,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,61.3,56.7,71.8,10,7,4,Disability,0 |
| HC003-0000022,0.45,Male,Black_non_Hispanic,US,Middle,B,Mild,6.3,Missense,0,0,None_on_demand,Non_factor,27.5,Every_other_day,15.9,18.8,0.55,317716,296213,1,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,27,20,0,0,0,0,0,0,4,11.2,7.3,None,61.0,15.4,0,1,39.9,1,0,43.6,107.7,103.0,1,47.0,1,35.6,81.2,1.42,65.3,429.4,0.195,10.22,9.34,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,23.7,56.9,50.4,9,10,9,Employed_full,0 |
| HC003-0000023,3.68,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,24.9,3x_week,16.1,13.4,0.902,148968,231266,1,0,20.7,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,28,21,1,2,0,0,0,0,8,0.0,4.3,Moderate,6.2,0.1,0,0,34.5,0,1,49.1,97.5,145.0,0,N/A,0,73.3,44.1,1.55,182.5,786.8,0.148,8.78,3.16,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,33,15.1,58.0,56.7,6,1,4,Disability,4 |
| HC003-0000024,2.45,Male,Hispanic,US,Low,A,Mild,24.38,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,20.8,Weekly_EHL,15.6,10.6,0.442,394567,275697,1,1,8.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,13,10,1,6,0,0,0,0,11,0.0,13.8,Mild,0.0,7.3,1,0,46.6,0,1,36.0,134.3,111.8,0,N/A,0,58.4,79.1,2.42,84.4,843.9,0.093,7.01,7.9,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,24.1,48.7,46.3,13,11,3,Disability,0 |
| HC003-0000025,1.31,Male,Black_non_Hispanic,US,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_SHL,33.8,Every_other_day,3.7,12.4,0.853,771267,216839,0,0,28.3,0,N/A,0.0,0,0,0,1,1.8,Low_titer,12,0,0,N/A,0,0,Emicizumab_bypass,0,4,3,0,0,0,0,0,1,5,31.0,15.3,None,15.7,17.9,1,0,14.0,1,1,24.0,125.3,104.7,0,N/A,0,25.0,96.6,2.74,58.7,598.6,0.088,9.65,9.29,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,8,38.5,59.7,54.3,3,5,5,Employed_part,2 |
| HC003-0000026,0.83,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Plasma_derived,18.6,3x_week,6.7,16.2,0.69,107201,196074,0,1,24.6,1,Monthly,0.947,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,0,17,32.4,15.9,None,45.2,1.1,0,0,14.9,1,1,38.1,105.3,129.1,0,N/A,1,56.4,113.1,3.66,19.6,793.2,0.696,3.35,53.55,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,25.3,56.3,92.5,6,0,9,Disability,1 |
| HC003-0000027,0.91,Male,Asian,Latin_America,Middle,A,Severe,0.1,Other,0,1,Primary,Recombinant_SHL,32.1,3x_week,10.8,11.5,0.923,354453,139826,0,0,23.0,0,N/A,0.0,0,0,0,1,1.4,Low_titer,24,0,0,N/A,0,0,Emicizumab_bypass,0,2,2,0,0,0,0,0,0,6,8.2,18.6,None,20.8,9.6,0,0,1.9,0,0,36.0,125.5,124.1,0,N/A,0,27.7,94.2,2.38,98.6,1015.2,0.64,1.75,5.41,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,33.8,59.4,51.7,4,0,1,Employed_full,4 |
| HC003-0000028,0.15,Male,White_non_Hispanic,US,Low,B,Mild,25.16,Splice_site,0,0,None_on_demand,Recombinant_SHL,44.6,Every_other_day,7.6,14.8,0.587,370798,270087,0,1,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,36,27,0,0,0,0,0,0,9,12.5,6.1,None,37.6,11.5,0,0,52.5,0,0,17.6,112.9,116.0,0,N/A,0,37.9,112.7,1.76,122.6,924.6,0.189,3.95,14.28,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Liver_failure_HCV,1,9,17.6,71.7,55.4,10,5,9,Employed_part,0 |
| HC003-0000029,0.36,Male,Hispanic,Europe,Middle,A,Mild,15.62,Missense,0,0,None_on_demand,Recombinant_SHL,39.9,Every_other_day,5.6,8.0,0.708,368267,300271,0,0,16.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,29,22,0,0,0,0,0,1,12,0.0,0.7,Mild,41.2,8.5,0,0,80.5,1,0,29.3,109.6,125.0,0,N/A,0,59.5,125.9,2.39,49.4,606.7,0.898,4.21,6.61,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,7,52.0,57.2,50.5,5,3,4,Employed_part,0 |
| HC003-0000030,1.37,Male,White_non_Hispanic,Latin_America,High,A,Mild,35.67,Small_indel,0,0,None_on_demand,Recombinant_SHL,16.0,Every_other_day,1.0,10.6,0.856,719053,174284,0,0,3.9,1,Biweekly,0.837,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,7,24.1,7.3,Severe,26.4,6.5,1,0,9.0,0,1,27.2,113.9,108.3,0,N/A,1,63.3,131.4,2.75,120.0,451.4,0.493,7.7,3.93,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,44.6,46.0,59.4,9,3,4,Unemployed,2 |
| HC003-0000031,0.78,Male,White_non_Hispanic,Latin_America,Low,A,Severe,0.1,Other,0,1,Primary,Recombinant_EHL,23.7,Every_other_day,3.9,15.7,0.603,910374,169658,1,1,17.6,1,Biweekly,0.966,1,0,1,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,9,14.7,16.7,None,6.4,2.7,1,0,42.8,1,0,29.4,140.0,115.8,0,N/A,0,46.6,104.8,2.92,98.3,691.4,0.354,6.75,16.16,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,25,26.1,75.6,61.0,11,7,3,Unemployed,0 |
| HC003-0000032,2.53,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Missense,0,1,Tertiary,Recombinant_SHL,31.4,3x_week,10.5,17.8,0.841,233260,398596,0,0,1.0,1,Biweekly,0.99,0,0,0,1,12.7,High_titer,16,0,0,N/A,0,0,aPCC,0,5,4,1,1,0,0,0,1,7,0.0,4.6,None,13.2,9.2,0,0,9.7,0,1,58.0,127.9,124.3,0,N/A,0,76.6,68.2,2.87,24.1,1072.5,0.6,10.06,40.55,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,14.5,65.8,79.1,4,13,4,Disability,1 |
| HC003-0000033,1.42,Male,White_non_Hispanic,Europe,Middle,A,Mild,10.7,Intron22_inversion,1,0,None_on_demand,Plasma_derived,27.4,Weekly_EHL,11.6,8.0,0.926,401878,178045,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,31,23,0,0,0,0,0,0,7,17.5,0.0,Moderate,0.0,7.4,0,0,16.1,1,0,48.1,109.0,88.4,0,N/A,0,62.5,65.1,2.69,120.0,890.8,0.494,0.89,9.35,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,30.1,62.5,56.3,0,2,10,Employed_full,1 |
| HC003-0000034,0.48,Female,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Missense,0,1,Secondary,Plasma_derived,16.8,Weekly_EHL,7.2,11.7,0.944,282248,186809,1,0,32.3,1,Weekly,0.698,0,0,0,1,29.6,High_titer,9,0,1,High_dose,1,42,rFVIIa,0,5,4,0,0,0,0,0,0,3,0.0,13.2,Mild,15.3,0.0,0,0,14.8,1,0,53.6,132.9,142.2,1,57.7,0,55.7,67.7,2.45,84.4,648.9,0.341,2.37,4.0,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,47.2,54.2,63.6,6,6,8,Employed_part,0 |
| HC003-0000035,0.92,Male,Hispanic,US,Middle,A,Mild,17.75,Intron22_inversion,1,0,None_on_demand,Plasma_derived,31.1,Biweekly_EHL,12.5,16.4,0.815,183640,229146,0,0,22.4,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,30,22,1,3,0,0,0,0,5,21.7,7.5,Mild,27.3,14.6,1,1,66.5,1,0,48.1,132.2,100.3,0,N/A,0,66.0,69.9,2.77,50.0,931.2,0.249,4.17,11.25,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,51.8,63.4,35.8,3,4,3,Employed_full,2 |
| HC003-0000036,1.28,Male,Hispanic,Europe,Middle,A,Mild,34.7,Small_indel,0,0,None_on_demand,Recombinant_SHL,27.9,3x_week,9.4,9.6,0.521,315681,171287,1,0,13.8,1,Biweekly,0.87,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,15,2.0,0.0,Mild,5.0,2.5,1,0,50.8,0,1,55.0,120.2,108.1,0,N/A,0,91.5,102.8,1.81,133.3,860.4,0.276,6.58,9.5,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,37.4,35.4,49.9,4,2,11,Unemployed,2 |
| HC003-0000037,0.69,Female,Hispanic,US,High,A,Severe,0.1,Large_deletion,1,1,Tertiary,Recombinant_EHL,43.3,Weekly_EHL,18.5,14.4,0.675,401475,119352,0,0,7.1,0,N/A,0.0,0,0,0,1,136.3,High_titer,15,1,1,Modified,1,15,Emicizumab_bypass,0,3,2,0,0,0,0,0,0,13,19.0,12.6,None,20.7,0.0,0,0,42.2,1,1,42.3,108.4,143.0,0,N/A,1,25.0,152.8,1.4,132.5,308.1,0.083,23.94,54.32,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.5,71.5,77.2,0,2,9,Unemployed,0 |
| HC003-0000038,0.64,Male,White_non_Hispanic,Europe,High,A,Mild,11.67,Intron22_inversion,1,1,Primary,Recombinant_EHL,26.0,Weekly_EHL,11.0,13.1,0.361,305638,217289,0,0,5.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,1,1,0,0,0,0,12,7.2,8.9,None,10.8,4.4,1,0,28.0,0,0,60.2,107.1,135.2,0,N/A,0,93.6,105.9,3.45,49.1,841.1,0.159,2.05,14.41,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,33.6,65.0,50.0,0,13,10,Disability,0 |
| HC003-0000039,1.76,Male,White_non_Hispanic,Europe,Low,A,Mild,33.75,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,37.3,Every_other_day,16.2,16.5,0.623,158149,176420,0,0,20.4,1,Biweekly,0.731,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,21,0.0,25.4,Severe,52.7,2.6,1,0,22.4,0,0,27.2,93.5,126.6,0,N/A,0,51.4,97.6,2.38,106.7,671.4,1.271,2.54,3.19,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,11,43.3,54.2,72.7,11,6,9,Disability,1 |
| HC003-0000040,0.59,Male,White_non_Hispanic,US,Middle,B,Moderate,4.4,Missense,0,1,Primary,Recombinant_SHL,17.9,3x_week,13.2,16.7,0.743,203183,451859,0,0,13.9,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,1,0,0,5,27.0,12.7,Mild,21.7,6.5,0,0,32.9,0,0,41.2,118.6,94.3,0,N/A,1,47.9,126.9,2.67,103.1,494.0,0.155,3.19,23.27,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,49.7,64.7,49.0,2,5,5,Employed_part,1 |
| HC003-0000041,2.67,Male,Black_non_Hispanic,Latin_America,Middle,A,Mild,7.77,Other,0,0,None_on_demand,Recombinant_SHL,19.8,3x_week,3.6,13.3,0.25,204118,266792,0,0,36.6,1,Biweekly,0.825,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,11,27.6,16.7,None,18.4,0.5,0,0,14.5,0,0,29.7,102.8,114.1,0,N/A,0,56.2,76.8,1.0,92.3,666.4,0.069,2.47,14.85,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,38.4,62.2,59.6,13,3,5,Employed_full,0 |
| HC003-0000042,2.78,Male,Asian,US,Low,A,Mild,22.12,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,33.8,Weekly_EHL,11.5,16.0,0.403,161868,133554,0,0,15.8,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,12,9,1,3,0,0,0,0,23,8.7,11.9,Severe,63.0,10.7,1,1,36.0,0,0,56.9,106.3,121.1,0,N/A,1,45.5,129.2,3.17,74.4,724.6,0.621,2.2,17.15,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,35.9,45.9,86.0,3,6,8,Employed_part,1 |
| HC003-0000043,2.17,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,36.7,3x_week,4.6,10.9,0.763,323879,258986,1,0,18.7,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,8,6,0,0,0,0,0,0,14,18.3,7.2,None,22.2,16.3,0,0,59.2,1,0,47.0,127.5,122.4,1,56.8,0,42.1,127.1,2.98,89.1,507.1,0.367,4.65,11.03,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,48.6,57.8,72.4,9,3,9,Employed_part,2 |
| HC003-0000044,0.15,Male,Hispanic,US,High,A,Mild,7.64,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,20.3,Every_other_day,11.4,17.1,0.497,344851,209805,0,1,1.3,1,Weekly,0.901,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,22,20.3,8.1,None,35.8,8.6,1,1,5.0,1,0,56.2,140.0,145.0,0,N/A,0,83.6,101.7,1.62,132.5,628.4,0.384,9.84,18.31,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,0,0,56.4,59.8,34.7,6,14,7,Employed_full,0 |
| HC003-0000045,2.27,Male,White_non_Hispanic,Europe,Low,A,Severe,0.1,Large_deletion,1,0,None_on_demand,Recombinant_SHL,28.2,Biweekly_EHL,7.5,11.3,0.636,482970,346180,0,0,13.7,0,N/A,0.0,0,0,0,1,6.8,High_titer,15,1,1,Modified,0,16,Emicizumab_bypass,0,50,38,0,0,0,0,0,0,6,20.6,20.6,Severe,32.9,0.0,0,0,5.1,0,0,25.2,122.5,145.0,1,43.4,1,68.5,158.6,2.24,111.4,590.5,0.266,4.93,10.99,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,36.8,54.7,100.0,10,7,8,Employed_full,2 |
| HC003-0000046,2.71,Male,White_non_Hispanic,US,Middle,A,Mild,28.73,Missense,0,0,None_on_demand,Recombinant_SHL,16.9,Every_other_day,14.3,8.5,0.738,160400,138382,0,0,20.1,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,45,34,0,0,0,0,0,0,18,35.7,18.0,Moderate,49.1,2.5,1,0,34.9,0,1,34.8,112.9,136.1,0,N/A,0,25.0,131.2,2.53,17.9,793.1,0.624,2.25,5.88,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,1,CNS_bleed,0,0,40.9,53.8,47.5,6,7,5,Disability,0 |
| HC003-0000047,2.24,Male,White_non_Hispanic,Europe,High,B,Mild,32.67,Missense,0,0,None_on_demand,Recombinant_SHL,26.6,Biweekly_EHL,3.9,13.5,0.729,189760,197667,0,0,13.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,11,8,0,0,0,0,0,0,3,20.0,0.1,Moderate,41.8,9.3,0,0,11.5,0,1,20.6,114.6,115.4,1,55.9,0,79.8,101.3,1.77,9.3,595.7,1.024,3.83,8.34,0,1,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,31.7,65.0,88.1,8,6,4,Employed_full,6 |
| HC003-0000048,0.56,Male,White_non_Hispanic,US,Middle,A,Mild,34.75,Missense,0,0,None_on_demand,Plasma_derived,34.7,Weekly_EHL,12.1,10.8,0.727,681970,171177,1,1,12.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,24,18,0,0,0,0,0,0,17,10.7,2.0,None,6.3,0.0,0,0,21.1,1,1,46.3,137.8,145.0,0,N/A,0,76.6,96.0,2.64,20.7,344.0,0.198,1.95,6.66,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.9,57.8,55.8,13,11,23,Disability,1 |
| HC003-0000049,0.64,Male,Hispanic,Latin_America,Middle,A,Moderate,4.98,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,24.5,Weekly_EHL,15.4,13.7,0.873,243118,185209,1,0,21.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,21,16,0,0,0,0,0,0,9,20.1,2.5,None,25.5,0.6,0,0,63.6,1,1,36.9,122.8,114.4,0,N/A,0,32.3,87.9,2.92,40.7,569.5,0.5,9.84,10.05,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,29.8,74.8,44.8,9,6,8,Employed_full,2 |
| HC003-0000050,0.33,Male,Asian,Other,High,A,Mild,39.34,Intron22_inversion,1,1,Secondary,Plasma_derived,26.0,Weekly_EHL,17.4,13.5,0.616,273233,115543,1,0,36.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,1,4,0,0,0,0,11,9.8,20.5,Severe,19.5,0.0,0,0,22.4,0,0,51.1,118.9,77.8,0,N/A,0,69.0,96.3,2.56,64.8,479.7,0.737,14.54,7.94,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,55.6,49.5,55.7,4,4,10,Disability,2 |
| HC003-0000051,0.71,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Plasma_derived,19.0,Every_other_day,7.4,8.6,0.88,241576,239895,1,0,19.7,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,4,2.2,0.0,None,14.8,8.7,0,1,46.8,0,1,42.4,120.3,102.5,0,N/A,0,78.7,97.1,1.62,76.9,417.1,0.19,1.25,5.57,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,12,49.7,60.1,52.9,0,7,6,Employed_part,1 |
| HC003-0000052,0.04,Male,Hispanic,Europe,Low,A,Severe,0.1,Large_deletion,1,1,Secondary,Recombinant_SHL,22.8,3x_week,12.1,14.3,0.507,529569,221678,0,0,31.7,1,Biweekly,0.828,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,7,29.6,18.3,Moderate,47.3,21.0,0,0,23.3,1,0,16.4,86.4,82.3,0,N/A,0,29.7,91.1,1.88,92.4,862.5,1.008,5.38,6.27,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,59.1,46.8,54.3,6,9,12,Unemployed,0 |
| HC003-0000053,0.33,Male,Black_non_Hispanic,Asia_Pacific,Low,A,Severe,0.1,Missense,0,1,Secondary,Recombinant_EHL,42.1,Weekly_EHL,13.1,16.9,0.737,542035,342016,0,1,25.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,16,21.4,15.2,Moderate,0.0,0.4,0,0,34.4,1,0,22.1,122.8,118.1,0,N/A,0,71.3,94.0,2.34,93.6,794.6,0.735,2.4,7.37,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,33.8,62.8,62.8,9,11,7,Employed_part,0 |
| HC003-0000054,2.63,Male,Other,Other,High,A,Moderate,1.43,Small_indel,0,1,Tertiary,Recombinant_SHL,28.6,Weekly_EHL,21.3,15.5,0.729,523308,178972,0,0,31.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,3,0.0,13.2,None,28.9,12.9,1,0,29.8,0,0,43.0,97.5,121.8,0,N/A,0,50.1,66.6,2.28,93.1,476.0,0.112,4.71,1.49,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,62.8,44.9,68.7,8,7,4,Employed_part,0 |
| HC003-0000055,7.99,Male,Hispanic,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_EHL,20.0,Every_other_day,3.1,23.3,0.535,272649,146397,0,0,10.7,0,N/A,0.0,0,0,0,1,13.8,High_titer,19,1,0,N/A,0,0,rFVIIa,1,1,1,0,0,1,0,0,1,8,6.8,8.2,Moderate,14.1,4.6,0,1,42.8,1,0,47.6,122.9,96.3,0,N/A,0,76.9,84.1,2.29,140.7,421.5,1.079,4.19,18.58,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.7,58.9,81.9,3,7,21,Unemployed,1 |
| HC003-0000056,1.13,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Small_indel,0,1,Secondary,Recombinant_SHL,25.5,Every_other_day,6.5,13.9,0.431,158981,266905,0,0,15.5,1,Biweekly,0.823,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,1,10,24.1,21.5,Severe,4.0,0.1,0,0,11.5,0,0,15.4,100.3,109.6,0,N/A,0,44.5,55.3,2.27,27.9,631.5,0.116,1.53,10.11,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,4,38.5,67.8,65.0,8,10,2,Employed_full,2 |
| HC003-0000057,0.57,Male,Hispanic,Asia_Pacific,Low,A,Mild,28.52,Intron22_inversion,1,1,Primary,Plasma_derived,15.2,3x_week,28.8,12.5,0.671,851818,120922,0,0,15.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,1,1,30,0.0,12.9,Moderate,41.7,17.4,0,0,40.9,0,0,41.0,126.8,99.3,1,55.3,1,87.9,111.6,1.5,108.4,411.8,0.174,11.79,4.26,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,HIV_AIDS,0,0,53.8,56.5,63.1,10,0,10,Employed_full,3 |
| HC003-0000058,0.8,Male,White_non_Hispanic,Latin_America,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_EHL,19.9,3x_week,10.4,22.0,0.687,448554,309432,0,0,24.6,1,Biweekly,0.902,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,8,6,0,0,0,0,0,0,13,6.0,0.4,Mild,19.7,21.0,0,0,4.2,1,0,29.8,111.9,122.7,0,N/A,0,59.6,102.2,2.8,108.2,606.4,0.52,3.97,12.58,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Liver_failure_HCV,1,10,28.8,46.1,51.9,14,6,6,Disability,1 |
| HC003-0000059,0.72,Male,Other,Europe,High,A,Severe,0.1,Large_deletion,1,0,None_on_demand,Recombinant_SHL,38.9,3x_week,1.0,12.3,0.689,204026,309100,0,0,27.5,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,36,27,0,0,0,0,0,0,13,46.9,2.3,Mild,37.5,10.5,0,0,28.1,1,1,28.7,92.1,109.6,0,N/A,0,51.5,96.6,2.71,44.5,662.7,0.693,3.08,4.68,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,3,40.4,65.5,58.1,6,4,10,Disability,1 |
| HC003-0000060,0.26,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Small_indel,0,1,Secondary,Plasma_derived,26.9,Weekly_EHL,8.5,8.0,0.757,630514,337270,0,0,19.5,1,Weekly,0.862,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,8,11.0,0.0,None,15.2,10.2,0,0,17.2,0,0,34.1,109.2,143.2,1,54.2,0,49.1,124.8,2.66,116.4,704.8,0.326,4.92,4.68,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,HIV_AIDS,0,0,38.3,59.6,54.9,19,6,29,Disability,0 |
| HC003-0000061,2.17,Male,Black_non_Hispanic,US,High,A,Severe,0.1,Large_deletion,1,1,Secondary,Recombinant_SHL,43.1,Weekly_EHL,1.0,15.0,0.735,194587,217143,0,0,28.5,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,9,28.0,21.6,None,20.2,8.4,0,0,74.9,1,0,43.5,140.0,128.1,0,N/A,0,84.2,75.8,2.61,109.9,711.2,0.182,2.23,10.35,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,44.6,55.1,42.8,14,7,10,Disability,0 |
| HC003-0000062,2.75,Male,White_non_Hispanic,Europe,Middle,A,Mild,31.92,Missense,0,0,None_on_demand,Plasma_derived,27.2,Weekly_EHL,13.4,11.7,0.841,625572,141033,0,0,11.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,18,14,0,0,0,0,0,0,21,33.0,23.4,Severe,25.7,7.1,0,1,37.3,1,0,33.5,69.5,145.0,0,N/A,0,49.1,80.1,2.26,93.3,509.5,0.245,3.87,26.78,1,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,6,35.1,46.3,97.7,8,11,14,Unemployed,0 |
| HC003-0000063,3.02,Male,White_non_Hispanic,Europe,Middle,C,Severe,0.1,N/A,0,1,Secondary,Plasma_derived,27.7,Every_other_day,16.9,14.4,0.75,651460,189965,1,1,28.6,1,Biweekly,0.764,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,21,4.1,20.7,Severe,7.4,10.0,0,0,9.6,0,0,18.2,118.3,116.8,0,N/A,0,88.3,58.5,2.1,5.0,662.7,0.223,1.03,9.51,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.1,39.9,65.4,8,0,10,Disability,0 |
| HC003-0000064,10.62,Male,Asian,Europe,High,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_EHL,33.1,3x_week,6.5,18.0,0.874,154370,217517,1,0,30.2,1,Weekly,0.916,0,0,0,1,34.0,High_titer,18,1,1,High_dose,0,32,rFVIIa,0,6,4,0,0,0,0,0,1,15,18.2,10.9,None,9.5,12.1,0,0,35.9,0,0,43.4,94.8,145.0,0,N/A,1,69.7,128.6,1.89,133.6,880.5,0.59,0.68,3.68,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,35.8,78.5,65.6,14,3,8,Unemployed,3 |
| HC003-0000065,4.21,Male,Hispanic,Europe,Middle,A,Mild,22.7,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,10.0,3x_week,9.2,9.7,0.569,380429,135935,0,0,26.1,1,Weekly,0.895,1,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,12,39.7,0.6,Moderate,75.3,18.0,0,0,40.4,1,0,37.8,140.0,125.0,0,N/A,0,34.5,117.0,3.17,104.1,272.5,0.218,2.06,5.38,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,18,36.8,50.3,79.0,2,2,12,Employed_full,7 |
| HC003-0000066,3.29,Male,White_non_Hispanic,Europe,Middle,A,Mild,36.95,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,29.6,Every_other_day,17.5,9.3,0.661,429044,350305,0,0,19.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,13,10,0,0,0,0,0,0,8,20.5,3.6,Severe,0.3,4.9,0,0,22.2,0,0,30.7,131.3,115.5,0,N/A,0,65.6,137.2,2.39,111.1,708.6,0.179,2.93,15.87,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.9,46.1,25.9,3,4,3,Employed_part,1 |
| HC003-0000067,2.09,Male,Other,Asia_Pacific,High,B,Mild,27.53,Splice_site,0,0,None_on_demand,Recombinant_SHL,27.6,Every_other_day,1.5,14.0,0.639,1288444,240396,0,0,26.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,22,16,0,0,0,0,0,0,31,43.4,4.1,Mild,0.0,8.8,0,1,44.9,1,0,38.3,118.7,145.0,0,N/A,0,66.0,144.3,1.57,5.0,437.9,0.092,1.1,10.63,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,54.2,59.1,93.3,1,1,3,Employed_full,4 |
| HC003-0000068,1.19,Male,Asian,US,Middle,A,Mild,35.92,Large_deletion,1,0,None_on_demand,Recombinant_EHL,39.9,3x_week,4.1,17.1,0.528,171892,115138,0,0,7.3,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,14,10,0,0,0,0,0,1,9,7.4,11.6,None,51.0,7.5,1,0,17.7,1,0,37.8,133.3,92.1,0,N/A,0,33.8,88.1,2.39,73.7,902.7,0.187,3.01,17.52,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,16.3,45.8,50.0,6,15,3,Employed_full,0 |
| HC003-0000069,0.09,Male,White_non_Hispanic,US,Middle,A,Mild,13.24,Small_indel,0,1,Tertiary,Plasma_derived,35.7,Every_other_day,10.6,14.8,0.893,633824,461131,0,0,20.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,18,36.6,23.1,None,26.1,14.1,0,0,39.4,1,0,42.5,119.9,115.1,0,N/A,1,65.2,80.1,1.36,37.7,797.1,0.274,2.92,10.53,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,48.4,61.0,49.6,3,9,8,Employed_part,1 |
| HC003-0000070,1.91,Male,Hispanic,Latin_America,High,A,Severe,0.1,Small_indel,0,1,Tertiary,Plasma_derived,18.9,3x_week,7.5,11.5,0.701,271145,188847,0,0,21.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,1,4,15.2,23.1,Mild,14.7,22.4,0,0,24.6,0,0,39.0,115.1,95.0,0,N/A,0,76.9,49.7,2.52,146.7,791.3,0.122,4.27,14.79,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,29,34.8,69.5,54.4,5,3,5,Disability,0 |
| HC003-0000071,1.24,Male,White_non_Hispanic,Asia_Pacific,Low,B,Mild,22.39,Nonsense,0,0,None_on_demand,Recombinant_EHL,37.9,Every_other_day,10.2,21.3,0.506,127412,104083,0,0,2.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,30,22,0,0,0,0,0,0,20,11.1,8.1,Severe,43.7,14.4,0,0,74.5,0,0,44.0,103.0,91.9,0,N/A,0,89.8,69.3,2.47,50.8,496.4,0.075,7.33,45.23,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,1,16,38.0,45.4,75.8,7,6,9,Employed_full,0 |
| HC003-0000072,3.02,Male,Hispanic,Other,Middle,A,Mild,30.54,Small_indel,0,0,None_on_demand,Recombinant_EHL,25.9,Every_other_day,4.4,28.1,0.554,249698,118762,0,0,23.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,16,12,0,0,0,0,0,0,16,22.7,0.0,None,14.2,12.8,1,0,24.5,0,1,41.4,107.8,87.8,1,53.5,0,88.9,90.9,2.13,154.2,697.5,0.66,17.63,2.19,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,28.0,53.0,92.0,0,4,3,Unemployed,8 |
| HC003-0000073,4.06,Male,White_non_Hispanic,Asia_Pacific,Low,B,Severe,0.1,Large_deletion,0,1,Primary,Non_factor,20.8,Every_other_day,13.3,18.9,0.618,268734,378470,1,1,3.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,3,13.7,2.7,None,11.8,13.4,0,0,63.4,0,0,51.8,105.7,136.1,0,N/A,0,117.6,42.3,1.93,133.1,717.5,0.135,6.31,64.48,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,4,40.5,60.3,85.0,14,7,15,Employed_full,0 |
| HC003-0000074,0.66,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Intron22_inversion,1,1,Tertiary,Recombinant_SHL,29.6,3x_week,11.1,10.9,0.391,142154,447975,0,0,12.9,1,Weekly,0.855,0,0,0,1,3.2,Low_titer,26,1,0,N/A,0,0,rFVIIa,0,2,2,0,0,0,0,0,1,10,14.0,21.5,Moderate,26.4,15.6,1,0,9.4,1,0,61.0,115.2,101.1,0,N/A,1,65.0,69.8,2.68,103.9,223.2,0.106,2.04,17.16,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,35.7,43.8,55.3,13,3,0,Disability,1 |
| HC003-0000075,0.1,Male,Asian,US,Low,B,Severe,0.1,Missense,0,0,None_on_demand,Plasma_derived,26.4,3x_week,15.3,12.7,0.604,323613,297968,0,0,18.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,11,8,0,0,0,0,0,0,5,20.8,13.9,Moderate,13.5,22.5,0,0,27.6,1,0,41.8,77.2,120.4,0,N/A,0,77.2,97.7,2.36,140.4,676.4,1.057,7.64,78.45,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,14,37.5,46.9,36.8,5,0,12,Employed_part,0 |
| HC003-0000076,1.85,Male,Other,Europe,Middle,A,Mild,12.1,Small_indel,0,1,Primary,Recombinant_SHL,40.3,3x_week,13.2,15.6,0.594,476720,347894,1,0,9.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,1,16,0.0,9.2,Severe,5.2,0.0,0,1,5.6,1,0,34.5,135.6,141.1,0,N/A,1,51.7,125.0,1.43,57.2,760.4,0.594,13.74,3.05,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,4,46.4,54.8,56.2,14,4,7,Employed_part,1 |
| HC003-0000077,5.11,Male,Asian,US,Low,A,Mild,12.4,Small_indel,0,0,None_on_demand,Recombinant_EHL,30.7,Every_other_day,13.2,17.6,0.603,309564,330482,0,0,19.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,50,38,0,0,0,0,0,0,11,5.4,8.6,Moderate,70.7,11.6,0,0,45.6,0,0,24.8,140.0,133.3,0,N/A,0,106.5,79.9,3.0,64.4,395.5,0.684,1.83,10.42,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,47.0,75.6,53.0,9,12,3,Employed_full,0 |
| HC003-0000078,1.64,Male,Other,Europe,Middle,A,Mild,39.23,Intron22_inversion,1,1,Secondary,Plasma_derived,29.6,Biweekly_EHL,3.3,13.6,0.527,193860,237627,1,0,18.8,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,0,10,23.7,6.0,Mild,34.2,0.0,0,1,45.8,0,0,49.8,106.4,132.5,0,N/A,1,45.4,103.6,1.93,131.9,758.4,0.451,1.91,8.53,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,55.6,47.5,39.0,12,0,11,Employed_full,0 |
| HC003-0000079,4.26,Male,Black_non_Hispanic,Other,Middle,A,Severe,0.1,Intron22_inversion,1,1,Tertiary,Recombinant_SHL,35.2,3x_week,15.0,12.1,0.826,245467,212038,1,0,8.2,1,Monthly,0.795,0,0,0,1,2.6,Low_titer,14,1,0,N/A,0,0,aPCC,0,5,4,0,0,0,0,0,0,5,26.9,2.4,Severe,27.8,13.7,0,0,37.3,0,0,31.2,138.5,145.0,0,N/A,0,105.5,152.2,1.74,57.4,667.9,0.86,1.44,16.37,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,33.5,53.2,70.2,0,10,3,Employed_part,0 |
| HC003-0000080,1.51,Male,Black_non_Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,36.7,Weekly_EHL,10.0,12.4,0.791,267607,235610,0,0,24.8,0,N/A,0.0,0,0,0,1,11.7,High_titer,16,1,0,N/A,0,0,rFVIIa,1,50,38,0,0,0,0,0,1,26,19.3,28.6,Mild,14.8,11.3,0,0,20.1,1,0,65.0,112.3,145.0,1,42.0,0,102.6,49.4,3.08,42.0,898.6,0.611,2.85,11.28,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,47.5,80.0,62.1,5,8,17,Employed_part,2 |
| HC003-0000081,2.63,Male,Black_non_Hispanic,Europe,Middle,A,Moderate,2.09,Intron22_inversion,1,1,Secondary,Recombinant_EHL,34.3,3x_week,11.0,12.0,0.793,305710,259888,1,0,8.8,1,Biweekly,0.821,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,11,8,0,0,0,0,0,0,9,18.3,25.7,Mild,40.3,4.7,0,0,6.7,0,0,65.0,103.0,102.5,0,N/A,0,47.7,130.4,2.93,82.1,575.6,0.229,6.04,10.2,0,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,47.0,64.0,69.0,10,4,6,Employed_full,0 |
| HC003-0000082,0.58,Male,White_non_Hispanic,US,Middle,A,Moderate,2.43,Missense,0,1,Secondary,Recombinant_EHL,39.4,Weekly_EHL,18.3,25.9,0.639,522248,124144,0,0,45.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,5,19.8,5.4,None,32.2,0.0,1,0,62.8,0,0,39.4,107.4,133.7,0,N/A,0,87.8,110.7,2.19,59.7,682.0,0.128,14.68,14.9,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,22,41.0,39.1,72.2,6,9,7,Employed_full,0 |
| HC003-0000083,0.27,Male,White_non_Hispanic,US,Middle,A,Mild,20.21,Missense,0,0,None_on_demand,Recombinant_SHL,32.9,Weekly_EHL,7.7,12.2,0.687,315895,259362,0,1,16.7,1,Biweekly,0.932,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,10,26.5,0.0,Mild,30.5,7.9,1,1,8.5,0,0,22.0,116.7,120.1,0,N/A,1,75.0,135.5,1.77,169.6,711.4,0.108,9.15,6.71,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,58.5,53.7,71.6,6,7,9,Employed_part,1 |
| HC003-0000084,0.28,Male,White_non_Hispanic,US,Middle,A,Mild,11.36,Small_indel,0,0,None_on_demand,Non_factor,29.3,3x_week,20.1,12.4,0.475,115657,372991,0,0,3.9,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,15,11,1,1,0,0,0,0,12,0.0,13.4,None,46.8,9.3,1,0,24.2,1,0,49.8,100.6,122.4,0,N/A,0,55.9,127.1,1.95,126.0,144.6,0.269,6.1,4.64,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,33.0,61.8,61.1,6,0,2,Employed_full,1 |
| HC003-0000085,0.24,Male,Hispanic,US,High,B,Mild,16.6,Missense,0,1,Primary,Non_factor,37.9,Weekly_EHL,20.7,22.6,0.723,191493,162237,1,0,6.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,3,8.9,10.8,Moderate,25.6,7.6,0,0,51.0,1,0,65.0,127.1,97.8,0,N/A,0,62.0,81.4,2.18,72.0,586.2,0.125,4.65,11.11,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,41.7,70.5,85.0,9,4,7,Employed_full,0 |
| HC003-0000086,0.11,Male,White_non_Hispanic,Other,Middle,A,Mild,18.91,Intron22_inversion,1,1,Secondary,Plasma_derived,27.3,Every_other_day,16.5,11.5,0.941,296444,153795,0,0,31.8,1,Monthly,0.857,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,11,14.1,17.0,None,44.7,4.3,0,1,22.5,0,0,26.3,104.6,115.4,0,N/A,0,70.8,100.1,3.01,54.9,665.5,0.159,6.13,4.64,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,43.4,69.9,55.1,8,4,18,Employed_full,0 |
| HC003-0000087,3.43,Male,White_non_Hispanic,Europe,Low,A,Mild,26.81,Small_indel,0,0,None_on_demand,Recombinant_SHL,28.3,Weekly_EHL,6.1,12.9,0.664,526747,228267,1,0,13.1,1,Biweekly,0.88,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,1,17.3,18.8,None,32.5,2.6,0,0,12.4,1,1,64.8,93.5,117.4,0,N/A,1,72.9,59.1,3.05,108.5,225.8,0.267,6.43,6.6,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,26.8,61.6,53.1,15,12,5,Disability,2 |
| HC003-0000088,0.9,Male,Hispanic,Asia_Pacific,High,A,Moderate,2.92,Missense,0,0,None_on_demand,Recombinant_EHL,41.8,3x_week,1.0,16.1,0.902,584614,129985,0,0,1.6,1,Monthly,0.843,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,4,0.0,2.6,Severe,0.0,7.7,0,0,31.5,0,0,19.8,114.6,145.0,0,N/A,0,97.9,85.4,2.48,142.5,771.4,0.922,12.71,2.02,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,53.9,63.2,58.8,2,4,1,Disability,0 |
| HC003-0000089,0.77,Male,White_non_Hispanic,Latin_America,Middle,B,Severe,0.1,Missense,0,1,Secondary,Plasma_derived,41.0,Every_other_day,18.5,14.2,0.396,778256,93115,0,0,28.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,1,4,0.0,22.2,Moderate,21.9,3.2,0,0,28.2,1,0,24.5,101.1,104.2,0,N/A,1,77.6,100.8,2.73,106.6,665.5,0.09,4.41,7.77,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,18,38.8,43.0,69.5,7,5,11,Employed_full,2 |
| HC003-0000090,1.87,Male,White_non_Hispanic,US,Low,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,27.9,Biweekly_EHL,12.7,8.7,0.489,290212,319291,0,0,13.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,5,14.8,9.2,Moderate,3.4,12.9,0,0,13.8,0,0,45.7,108.5,82.1,0,N/A,0,48.1,108.5,2.3,57.0,664.4,0.308,5.53,3.2,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,44.8,49.1,71.6,11,1,5,Unemployed,0 |
| HC003-0000091,0.37,Male,Black_non_Hispanic,US,Middle,A,Severe,0.1,Missense,0,1,Primary,Recombinant_SHL,24.4,Weekly_EHL,7.5,14.9,0.764,424211,143562,0,0,25.8,1,Weekly,0.644,0,0,0,1,9.1,High_titer,14,0,1,Malmö,1,44,aPCC,0,6,4,0,0,0,0,0,0,10,27.2,16.9,Moderate,0.0,7.5,0,0,56.8,1,0,54.2,113.9,124.9,0,N/A,0,81.4,122.1,1.96,37.5,779.8,0.111,3.23,7.17,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,32,57.4,43.0,57.2,1,6,10,Employed_full,5 |
| HC003-0000092,3.84,Female,Asian,Asia_Pacific,Low,B,Severe,0.1,Missense,0,1,Secondary,Non_factor,39.7,Every_other_day,19.0,22.1,0.463,112120,181539,0,0,29.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,1,14,10.0,9.9,None,0.0,0.0,1,0,27.2,0,0,41.2,88.2,102.4,0,N/A,0,26.6,144.3,1.65,79.9,576.0,0.193,4.91,2.78,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,19,42.4,66.3,57.5,5,1,11,Employed_part,1 |
| HC003-0000093,2.58,Male,White_non_Hispanic,US,Low,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_SHL,34.4,Biweekly_EHL,6.8,9.0,0.798,347295,132579,1,0,21.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,11,7.0,19.4,None,25.5,9.1,0,1,33.1,1,0,47.4,140.0,122.5,0,N/A,0,56.5,87.8,2.56,107.6,657.8,0.634,3.65,7.26,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,19,40.4,59.8,80.3,8,10,4,Employed_full,0 |
| HC003-0000094,0.66,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Mild,37.31,Intron22_inversion,1,1,Secondary,Recombinant_EHL,30.5,3x_week,9.5,21.1,0.822,140764,340570,0,0,46.8,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,13,21.3,0.0,Moderate,32.3,10.5,1,0,17.0,0,0,55.3,131.3,136.9,0,N/A,1,58.6,132.1,2.85,76.2,805.7,0.153,1.73,16.61,0,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.7,57.1,43.7,15,4,4,Employed_full,2 |
| HC003-0000095,0.4,Male,White_non_Hispanic,US,Low,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,25.4,3x_week,15.1,16.4,0.643,258455,275568,0,0,1.0,0,N/A,0.0,0,0,0,1,42.9,High_titer,15,1,1,High_dose,0,43,aPCC,0,26,20,0,0,0,0,0,1,7,11.1,17.9,Moderate,0.0,17.7,1,0,28.7,1,1,56.6,102.4,123.2,1,51.5,0,79.5,107.5,2.14,135.3,660.0,0.244,9.01,4.32,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,28.9,71.4,100.0,8,1,9,Unemployed,0 |
| HC003-0000096,1.06,Male,Black_non_Hispanic,Latin_America,High,A,Mild,39.53,Intron22_inversion,1,0,None_on_demand,Plasma_derived,30.7,Weekly_EHL,5.3,12.8,0.663,1652671,159473,0,0,8.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,28,21,0,0,0,0,0,1,9,25.6,5.3,None,11.8,13.6,1,0,21.2,0,1,34.5,114.6,117.2,0,N/A,0,104.0,63.4,2.99,116.1,318.1,0.337,14.74,3.19,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,35.8,61.4,57.8,11,11,5,Employed_full,0 |
| HC003-0000097,0.61,Male,Asian,Asia_Pacific,High,A,Mild,27.81,Intron22_inversion,1,1,Tertiary,Recombinant_EHL,27.8,3x_week,11.3,18.4,0.476,321944,99713,1,0,14.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,5,12.3,12.6,None,13.9,2.6,1,1,22.2,1,0,31.6,127.7,122.2,0,N/A,0,69.8,95.8,2.21,104.5,659.3,0.528,4.35,14.93,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,38.3,67.4,59.1,11,1,25,Employed_full,0 |
| HC003-0000098,0.15,Male,White_non_Hispanic,US,Middle,A,Mild,29.5,Missense,0,1,Secondary,Plasma_derived,22.7,3x_week,18.5,14.3,0.746,159805,151227,1,0,45.1,1,Weekly,0.99,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,1,1,0,0,0,0,2,1.6,22.0,None,6.9,16.6,0,0,42.9,1,1,54.6,119.2,140.3,0,N/A,0,57.0,103.2,2.44,115.3,661.5,0.194,5.85,16.81,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,41.1,63.6,67.2,0,7,11,Employed_part,3 |
| HC003-0000099,1.01,Male,Black_non_Hispanic,US,Middle,A,Mild,16.26,Intron22_inversion,1,0,None_on_demand,Plasma_derived,29.0,Weekly_EHL,13.3,16.2,0.669,342721,239205,0,1,39.6,1,Weekly,0.853,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,10,32.0,5.6,Mild,31.1,0.0,0,0,59.6,1,1,47.5,140.0,104.2,0,N/A,0,49.6,76.6,2.29,39.4,812.1,0.826,8.93,10.82,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Surgical_complication,0,0,55.2,64.5,69.4,7,0,7,Employed_full,0 |
| HC003-0000100,4.5,Male,White_non_Hispanic,Other,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,30.1,Every_other_day,19.5,14.2,0.694,196763,197663,1,0,33.5,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,1,8,29.8,4.3,None,27.4,8.2,0,1,14.6,1,0,49.1,110.2,138.1,1,41.2,1,83.4,70.9,3.02,75.1,588.2,0.211,4.0,4.86,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,50.2,45.6,52.8,5,7,3,Disability,2 |
| HC003-0000101,2.02,Male,White_non_Hispanic,US,High,A,Mild,35.0,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,25.0,3x_week,18.8,17.3,0.911,150776,189956,0,0,8.5,0,N/A,0.0,0,0,1,0,0.0,None,0,1,0,N/A,0,0,N/A,0,50,38,1,4,0,0,0,0,18,3.5,9.0,None,0.0,12.5,0,0,34.4,0,0,34.1,138.8,106.9,0,N/A,0,60.7,69.9,2.65,53.4,474.0,0.444,5.22,4.19,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,33.5,65.7,66.7,15,10,2,Employed_full,1 |
| HC003-0000102,6.16,Male,Other,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,35.2,3x_week,12.0,18.0,0.887,947786,199955,0,0,9.9,1,Biweekly,0.872,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,8,6,0,0,0,0,0,0,34,19.7,8.5,None,7.1,16.8,0,0,36.7,1,0,49.7,88.3,135.8,0,N/A,0,53.9,84.8,2.37,110.4,474.6,0.259,3.77,5.48,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.7,60.7,48.9,10,3,7,Employed_full,2 |
| HC003-0000103,4.09,Male,White_non_Hispanic,Europe,Low,A,Mild,12.62,Intron22_inversion,1,0,None_on_demand,Plasma_derived,38.3,Weekly_EHL,1.0,15.2,0.72,508941,262866,0,0,8.1,0,N/A,0.0,1,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,50,38,0,0,0,0,0,0,19,11.1,3.6,Mild,28.3,19.3,1,0,35.3,0,0,28.9,91.4,97.2,0,N/A,0,85.9,75.8,2.44,54.0,909.7,0.545,2.89,7.01,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,55.4,51.9,53.6,11,1,11,Employed_full,2 |
| HC003-0000104,2.24,Male,White_non_Hispanic,US,Middle,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_SHL,35.8,Every_other_day,5.4,10.5,0.876,330156,176146,0,0,8.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,20,22.4,12.9,Mild,20.8,15.6,0,1,11.8,0,0,45.0,140.0,134.8,0,N/A,0,90.7,134.5,1.81,98.3,702.1,1.525,6.8,1.56,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,21.0,62.8,39.5,10,1,19,Employed_full,2 |
| HC003-0000105,3.7,Male,White_non_Hispanic,Latin_America,Middle,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_SHL,25.8,Every_other_day,16.6,8.9,0.714,212120,225259,1,0,35.9,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,1,11,4.5,13.3,None,9.7,7.2,1,0,5.8,0,0,43.3,106.4,123.2,0,N/A,0,43.9,31.4,1.28,88.4,900.5,0.241,6.75,3.05,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,4,37.5,68.9,64.0,8,6,12,Unemployed,2 |
| HC003-0000106,1.45,Male,Hispanic,Latin_America,Low,A,Mild,8.72,Intron22_inversion,1,0,None_on_demand,Plasma_derived,34.0,Weekly_EHL,2.7,13.5,0.535,222688,109814,0,0,15.1,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,34,26,0,0,0,0,0,0,7,25.5,15.7,None,35.2,11.5,0,0,18.6,1,0,43.4,91.7,126.7,0,N/A,0,32.1,103.1,2.13,119.0,926.5,0.297,9.37,22.78,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,25.6,55.0,59.5,11,14,6,Unemployed,0 |
| HC003-0000107,2.14,Female,Other,Europe,Middle,A,Mild,39.06,Small_indel,0,0,None_on_demand,Recombinant_SHL,28.6,Every_other_day,10.0,11.2,0.878,677042,644948,0,1,16.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,50,38,0,0,0,0,0,0,17,29.3,5.4,None,55.7,9.3,0,1,40.1,1,0,51.4,114.0,142.3,0,N/A,1,62.8,114.8,2.3,47.1,516.2,0.213,4.47,8.91,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,16,66.9,48.5,33.8,7,10,4,Unemployed,0 |
| HC003-0000108,0.76,Male,Other,Asia_Pacific,Low,A,Moderate,2.98,Intron22_inversion,1,0,None_on_demand,Plasma_derived,18.1,3x_week,14.0,13.0,0.699,322528,156072,1,1,27.3,0,N/A,0.0,0,0,0,1,23.3,High_titer,47,1,0,N/A,0,0,aPCC,0,10,8,1,3,0,0,0,0,16,3.6,4.4,Mild,0.0,3.7,0,0,56.3,1,0,29.8,140.0,110.2,0,N/A,0,39.9,73.0,2.67,113.1,502.4,0.188,1.72,22.29,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,48.5,49.0,52.5,13,11,12,Employed_full,1 |
| HC003-0000109,0.44,Male,White_non_Hispanic,US,High,A,Mild,35.24,Missense,0,0,None_on_demand,Recombinant_SHL,33.4,Weekly_EHL,20.8,14.2,0.509,42206,199147,0,0,1.0,1,Monthly,0.943,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,5,15.8,11.1,None,58.0,7.3,0,0,6.3,1,0,50.1,99.7,124.5,1,46.4,0,36.9,93.5,2.32,52.2,627.0,0.172,10.87,18.43,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,34.5,42.0,61.6,2,2,3,Disability,1 |
| HC003-0000110,4.29,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_EHL,29.2,Weekly_EHL,8.5,20.3,0.62,1146888,238764,0,0,18.6,1,Biweekly,0.843,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,8,29.6,10.0,Severe,13.5,18.8,1,1,41.3,0,0,42.2,114.2,130.5,0,N/A,0,42.1,90.4,2.17,56.4,760.6,0.297,2.49,5.58,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.6,54.3,74.0,12,10,9,Employed_full,0 |
| HC003-0000111,0.28,Male,Black_non_Hispanic,Europe,Low,B,Mild,15.63,Nonsense,0,0,None_on_demand,Recombinant_EHL,48.7,Every_other_day,8.1,21.7,0.828,299490,146474,1,0,4.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,15,11,0,0,0,0,0,0,5,3.0,10.2,None,20.9,11.9,0,0,11.0,1,0,32.5,77.9,119.6,0,N/A,0,88.0,97.8,1.0,89.3,397.7,0.162,2.46,5.65,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,31.0,61.9,44.1,5,10,10,Employed_full,0 |
| HC003-0000112,0.38,Male,White_non_Hispanic,Other,Low,B,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_SHL,39.7,Weekly_EHL,11.7,13.2,0.514,329727,180577,0,0,14.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,1,5,7.0,6.3,Moderate,0.0,20.4,1,0,66.6,1,0,26.1,105.6,137.9,0,N/A,0,79.3,118.6,2.66,142.8,731.9,0.166,2.93,17.64,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,61.9,73.3,57.8,10,7,8,Disability,1 |
| HC003-0000113,0.62,Male,Asian,US,Low,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_SHL,33.7,Weekly_EHL,14.1,10.4,0.72,515049,179483,1,0,11.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,45,22.9,14.6,None,21.8,1.5,0,0,21.3,0,1,64.7,134.9,130.9,1,60.3,0,119.1,116.1,2.51,61.3,722.8,0.024,1.11,14.63,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,14,14.8,47.9,46.6,0,3,7,Employed_full,1 |
| HC003-0000114,1.93,Male,Hispanic,US,Middle,B,Severe,0.1,Nonsense,0,1,Secondary,Recombinant_SHL,30.0,3x_week,11.1,12.4,0.704,354776,113889,0,0,10.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,17,13.1,4.5,Mild,33.1,5.7,1,0,45.9,1,0,41.2,99.3,114.6,1,36.3,0,50.9,83.2,2.81,23.9,447.4,0.912,3.77,17.97,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,43.6,59.6,72.2,8,10,4,Disability,1 |
| HC003-0000115,0.83,Male,White_non_Hispanic,Europe,Low,B,Severe,0.1,Missense,0,1,Secondary,Non_factor,29.3,Weekly_EHL,18.3,27.2,0.708,420057,223976,0,0,20.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,10,0.0,11.0,Moderate,24.9,10.5,0,0,20.6,1,0,37.7,89.6,145.0,1,39.4,0,94.3,57.9,2.41,57.2,453.7,1.122,7.36,7.3,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,9,39.2,56.2,52.6,6,3,14,Unemployed,1 |
| HC003-0000116,1.37,Female,Asian,Asia_Pacific,Middle,A,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_SHL,20.0,Weekly_EHL,7.2,11.2,0.677,208098,78857,0,0,20.7,0,N/A,0.0,0,0,0,1,11.5,High_titer,24,0,1,Low_dose,1,11,Emicizumab_bypass,0,31,23,0,0,0,0,0,0,6,11.2,9.5,None,27.0,12.5,0,0,60.5,0,0,28.3,99.5,135.1,1,43.8,1,75.9,104.6,2.97,79.6,730.0,0.506,3.17,8.4,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,28.7,55.9,69.3,7,9,4,Employed_full,2 |
| HC003-0000117,4.32,Male,White_non_Hispanic,US,Low,B,Moderate,4.42,Large_deletion,0,0,None_on_demand,Recombinant_SHL,14.1,3x_week,12.7,14.1,0.753,128300,432075,0,0,15.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,19,14,0,0,0,0,0,0,20,36.0,11.7,None,27.5,7.3,0,0,30.7,1,0,55.1,102.8,109.8,1,45.3,0,52.8,81.6,2.12,169.8,1023.1,0.15,13.07,5.87,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,0,0,37.2,40.7,57.0,0,4,15,Unemployed,1 |
| HC003-0000118,3.08,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_SHL,21.0,3x_week,14.7,13.8,0.778,317470,267396,1,0,22.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,21,16,0,0,0,0,0,0,11,39.8,21.5,None,23.2,12.8,0,0,20.8,0,0,54.1,130.3,109.7,0,N/A,0,61.8,85.2,2.38,110.5,596.9,0.11,12.44,7.04,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,1,CNS_bleed,1,10,22.2,45.9,38.1,7,2,10,Disability,2 |
| HC003-0000119,2.34,Male,Hispanic,Latin_America,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,27.6,Weekly_EHL,9.6,9.6,0.457,633471,247598,0,0,7.6,0,N/A,0.0,0,0,0,1,17.5,High_titer,10,1,1,Malmö,1,23,aPCC,0,1,1,0,0,0,0,0,0,19,7.4,1.5,Mild,2.1,12.8,0,0,1.9,1,0,51.8,122.6,121.0,0,N/A,0,52.7,106.3,2.52,64.9,709.4,0.086,9.13,3.99,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,57.3,74.1,61.0,8,4,1,Disability,0 |
| HC003-0000120,0.34,Male,White_non_Hispanic,Europe,Middle,A,Moderate,4.08,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,11.2,Biweekly_EHL,17.0,8.5,0.722,181919,75484,1,0,26.2,0,N/A,0.0,1,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,35,26,0,0,0,0,0,0,12,4.0,0.0,Severe,5.5,0.0,1,0,26.8,0,0,41.3,126.5,133.1,0,N/A,0,70.7,87.8,2.73,89.3,541.1,0.502,0.95,6.91,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.3,66.1,45.4,0,14,6,Employed_full,1 |
| HC003-0000121,2.38,Male,Black_non_Hispanic,US,Middle,A,Severe,0.1,Missense,0,1,Primary,Plasma_derived,23.6,3x_week,12.9,12.0,0.708,173370,121023,0,0,15.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,1,4,9.5,7.2,Mild,0.9,12.5,0,0,55.7,0,1,51.0,115.6,85.2,0,N/A,0,86.7,108.6,2.61,157.8,692.6,0.829,14.11,6.4,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,50.1,58.8,77.7,1,1,4,Disability,3 |
| HC003-0000122,0.91,Male,Hispanic,US,Low,A,Mild,28.63,Large_deletion,1,0,None_on_demand,Recombinant_EHL,26.0,Weekly_EHL,16.7,25.4,0.602,558278,360293,1,1,12.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,50,38,1,3,0,0,0,0,5,36.6,2.8,Moderate,49.6,14.4,1,0,15.8,1,0,32.1,102.6,110.6,0,N/A,1,56.9,170.4,2.64,85.4,537.4,0.344,3.71,4.89,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.7,60.6,87.5,8,10,6,Employed_full,0 |
| HC003-0000123,0.25,Male,Other,Europe,Low,A,Mild,21.35,Small_indel,0,0,None_on_demand,Recombinant_EHL,26.3,Weekly_EHL,13.2,19.3,0.675,203955,1433487,1,1,8.5,1,Biweekly,0.78,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,7,5,0,0,0,0,0,0,10,25.1,0.0,None,54.2,9.8,0,0,40.0,0,0,44.6,99.5,114.6,0,N/A,1,83.7,119.2,2.53,85.9,603.4,0.598,17.16,15.06,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,54.8,63.4,70.9,9,9,7,Employed_full,0 |
| HC003-0000124,0.8,Male,Other,Europe,Low,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,22.7,Weekly_EHL,14.3,20.8,0.63,209748,326879,1,0,15.1,0,N/A,0.0,0,0,0,1,6.1,High_titer,38,1,0,N/A,0,0,aPCC,0,26,20,0,0,0,0,0,0,18,32.6,26.0,Mild,11.5,0.0,0,0,19.0,1,0,41.3,123.6,99.1,0,N/A,1,93.0,137.7,2.3,78.8,1090.8,0.43,2.76,2.08,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.4,51.5,53.0,7,5,14,Employed_full,0 |
| HC003-0000125,0.14,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Mild,16.31,Intron22_inversion,1,1,Secondary,Recombinant_EHL,25.3,Biweekly_EHL,8.2,17.9,0.789,214510,302087,1,0,40.4,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,4,27.0,16.5,Moderate,0.0,6.3,0,0,14.4,0,0,45.2,140.0,106.6,0,N/A,0,97.9,114.3,2.85,122.8,669.3,0.163,4.01,10.01,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,17,51.8,51.9,62.3,7,4,2,Employed_part,4 |
| HC003-0000126,1.83,Male,White_non_Hispanic,Europe,High,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_SHL,41.8,Every_other_day,8.2,16.5,0.728,258077,233862,1,0,17.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,1,0,1,8,0.0,17.3,None,7.0,10.6,1,0,7.8,0,0,20.2,96.2,127.5,1,34.8,0,39.2,102.2,1.56,74.0,368.4,0.675,4.81,3.22,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,7,46.2,49.8,66.1,7,1,4,Employed_full,3 |
| HC003-0000127,1.94,Male,Black_non_Hispanic,Latin_America,High,A,Severe,0.1,Large_deletion,1,1,Primary,Recombinant_EHL,33.3,Every_other_day,19.3,25.3,0.835,104382,117742,1,0,4.3,0,N/A,0.0,0,0,0,1,1.6,Low_titer,28,1,0,N/A,0,0,aPCC,0,4,3,0,0,0,0,0,1,9,3.6,9.7,None,17.4,2.8,1,0,25.2,1,0,64.4,94.6,116.2,0,N/A,1,63.9,114.7,2.09,129.9,765.7,0.642,2.13,3.45,0,1,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,38,39.6,57.7,77.2,4,11,7,Disability,1 |
| HC003-0000128,0.59,Male,Other,Other,Middle,A,Mild,15.04,Missense,0,0,None_on_demand,Recombinant_EHL,23.5,3x_week,15.8,18.5,0.747,194152,295844,0,0,29.0,1,Weekly,0.99,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,7,5,0,0,0,0,0,0,8,6.6,15.4,None,21.8,13.5,0,0,27.9,0,0,61.4,92.3,117.6,0,N/A,0,80.6,113.4,3.2,137.5,853.3,0.136,1.23,3.72,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,51.0,44.5,59.4,6,1,14,Employed_full,2 |
| HC003-0000129,0.09,Male,White_non_Hispanic,Europe,Middle,A,Mild,9.76,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,27.5,3x_week,5.9,25.9,0.862,308113,103714,0,0,12.3,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,50,38,1,1,0,0,0,0,16,8.7,8.6,None,15.1,12.4,1,0,51.7,1,0,28.2,131.6,100.2,1,60.6,0,41.1,124.2,2.06,119.5,771.6,0.574,0.66,11.29,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,70.0,49.4,67.7,0,0,4,Employed_full,1 |
| HC003-0000130,5.46,Male,White_non_Hispanic,Europe,Middle,A,Mild,24.23,Missense,0,0,None_on_demand,Recombinant_EHL,27.8,3x_week,13.1,16.6,0.668,306797,98195,1,0,21.4,1,Monthly,0.82,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,4,6.9,18.5,Severe,24.7,8.8,0,0,14.5,0,0,48.9,114.2,121.2,0,N/A,0,36.2,101.7,2.36,86.0,618.2,0.268,47.57,0.97,1,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,27.6,61.1,38.5,4,7,2,Employed_full,2 |
| HC003-0000131,1.62,Male,White_non_Hispanic,Other,Middle,A,Severe,0.1,Small_indel,0,1,Secondary,Recombinant_SHL,21.9,Weekly_EHL,1.0,8.1,0.676,537560,95152,0,1,10.7,1,Biweekly,0.812,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,10,8.3,13.5,None,10.1,8.1,0,0,52.7,0,0,24.2,126.1,97.9,0,N/A,0,64.4,63.4,3.09,39.1,484.9,0.244,1.18,8.6,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,38.7,52.5,65.4,7,1,2,Employed_part,2 |
| HC003-0000132,2.98,Male,White_non_Hispanic,US,Middle,B,Mild,20.63,Missense,0,0,None_on_demand,Recombinant_SHL,21.8,Biweekly_EHL,8.6,12.1,0.764,809066,292980,0,0,33.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,45,34,0,0,0,1,1,0,16,22.7,11.7,None,24.1,9.2,0,0,3.7,1,0,43.0,104.8,145.0,1,60.2,0,55.9,58.9,2.34,86.0,489.3,0.412,1.19,7.7,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,25.8,38.5,50.0,13,6,2,Employed_full,2 |
| HC003-0000133,0.71,Male,Hispanic,Latin_America,High,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,36.1,3x_week,17.8,11.3,0.668,664965,174782,0,0,10.9,0,N/A,0.0,0,0,0,1,31.6,High_titer,14,1,0,N/A,0,0,aPCC,0,2,2,0,0,0,0,0,1,15,16.6,12.3,None,2.0,8.0,0,0,7.0,0,0,15.7,127.4,145.0,0,N/A,0,61.2,112.9,1.98,68.3,615.8,0.402,7.08,3.09,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,44.6,52.2,62.6,6,1,3,Disability,0 |
| HC003-0000134,3.35,Male,White_non_Hispanic,Latin_America,High,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Plasma_derived,24.6,Weekly_EHL,11.2,12.3,0.634,464535,189175,0,0,34.8,1,Weekly,0.97,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,1,2,29.6,23.7,None,9.0,0.3,1,0,22.7,0,0,38.5,109.2,116.5,0,N/A,0,54.6,68.5,3.0,63.8,584.0,0.613,1.43,8.71,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,3,42.5,61.5,47.5,17,4,4,Employed_full,2 |
| HC003-0000135,3.28,Male,Black_non_Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,19.2,Every_other_day,12.7,12.6,0.663,245428,178492,0,0,5.4,0,N/A,0.0,0,0,0,1,1.3,Low_titer,14,1,0,N/A,0,0,Emicizumab_bypass,0,4,3,0,0,0,0,0,0,0,18.0,13.3,None,17.5,5.4,0,0,3.5,0,1,36.1,84.1,104.8,0,N/A,0,112.5,119.2,2.26,85.4,549.5,0.153,1.24,2.48,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,33,61.4,57.2,67.8,17,6,10,Employed_part,2 |
| HC003-0000136,0.19,Male,Asian,Europe,Middle,A,Mild,22.93,Intron22_inversion,1,1,Primary,Plasma_derived,27.7,3x_week,1.0,15.4,0.781,184639,102451,0,0,14.5,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,24,6.9,3.8,None,5.6,8.4,1,1,14.0,0,0,55.9,133.5,140.4,0,N/A,0,54.8,137.5,2.29,114.2,868.8,0.474,0.45,7.1,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,37.2,39.1,70.9,7,7,3,Disability,0 |
| HC003-0000137,10.86,Male,Asian,US,High,B,Severe,0.1,Large_deletion,0,1,Primary,Plasma_derived,28.9,Every_other_day,9.6,12.3,0.835,271231,128622,1,0,34.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,1,8,17.3,14.7,None,16.6,16.5,1,0,37.8,1,0,62.0,114.3,135.7,0,N/A,0,77.9,93.8,1.41,70.1,815.8,0.119,5.66,2.4,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,50.5,66.3,58.7,5,11,3,Disability,1 |
| HC003-0000138,1.35,Male,White_non_Hispanic,US,Middle,A,Mild,12.54,Small_indel,0,0,None_on_demand,Recombinant_EHL,12.2,3x_week,14.0,19.6,0.602,381302,131898,0,0,20.0,1,Monthly,0.936,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,5,0.0,15.9,None,25.6,12.2,0,0,14.6,0,0,62.3,108.8,145.0,0,N/A,0,76.4,133.9,2.34,40.0,878.1,0.261,1.9,46.77,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,17.1,53.5,49.9,18,6,10,Employed_part,1 |
| HC003-0000139,2.8,Male,White_non_Hispanic,Europe,High,B,Mild,37.85,Nonsense,0,1,Primary,Recombinant_EHL,27.7,3x_week,14.8,18.7,0.927,439399,89087,0,0,45.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,1,1,0,0,0,0,9,0.0,10.8,Moderate,20.7,16.8,1,0,44.6,0,1,55.9,120.6,145.0,1,58.2,0,27.8,107.3,2.74,56.7,508.1,0.275,7.5,16.04,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,41.7,59.4,70.0,11,6,12,Employed_full,2 |
| HC003-0000140,0.49,Male,Black_non_Hispanic,US,Low,A,Mild,27.35,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,34.9,Weekly_EHL,17.8,10.9,0.745,389980,139790,0,0,14.8,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,37,28,0,0,0,0,0,0,11,22.7,11.6,Mild,0.0,0.0,0,0,25.8,0,0,43.0,86.1,88.5,0,N/A,0,97.3,100.7,2.18,162.6,484.3,0.654,4.22,9.22,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,30.4,66.4,83.8,9,5,0,Employed_full,0 |
| HC003-0000141,1.97,Male,Black_non_Hispanic,Latin_America,High,A,Mild,36.49,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,31.6,3x_week,10.7,10.0,0.899,249520,104752,0,0,21.1,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,24,18,0,0,0,0,0,0,31,27.2,3.5,Moderate,25.7,5.9,0,0,27.0,0,0,46.7,123.6,145.0,1,49.8,0,78.8,102.0,1.76,116.9,663.9,0.303,4.8,3.13,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,46.5,54.8,88.9,3,10,8,Employed_full,3 |
| HC003-0000142,0.57,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Mild,8.82,Small_indel,0,0,None_on_demand,Recombinant_SHL,45.8,3x_week,11.0,8.0,0.653,430248,240106,0,0,40.9,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,29,22,0,0,0,0,0,0,19,15.9,12.8,None,60.9,20.4,0,0,5.1,1,0,46.6,103.1,121.0,0,N/A,1,68.5,76.7,2.16,56.7,724.7,0.244,3.12,5.77,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,52.7,36.9,67.5,5,1,4,Disability,0 |
| HC003-0000143,3.23,Male,Asian,Asia_Pacific,Low,B,Severe,0.1,Nonsense,0,1,Primary,Recombinant_EHL,38.0,Every_other_day,4.0,19.6,0.643,571788,250318,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,10,10.3,2.3,None,2.9,3.5,1,0,20.4,1,1,27.8,111.9,134.9,0,N/A,0,88.3,73.2,2.09,146.6,662.9,0.942,3.59,5.98,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,27,33.4,73.6,65.9,2,4,4,Employed_full,2 |
| HC003-0000144,0.93,Male,White_non_Hispanic,US,Middle,C,Severe,0.1,N/A,0,1,Secondary,Recombinant_EHL,39.6,Every_other_day,10.8,16.4,0.589,455020,94200,1,1,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,9,0.0,10.0,Severe,9.7,3.4,0,0,20.6,0,0,55.8,137.8,139.0,1,31.0,0,63.9,54.0,2.27,85.4,712.4,0.214,2.19,9.19,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,10,45.9,33.9,43.6,14,6,18,Disability,5 |
| HC003-0000145,1.56,Male,Asian,US,Low,A,Moderate,1.08,Small_indel,0,0,None_on_demand,Recombinant_EHL,50.4,Biweekly_EHL,4.4,29.6,0.689,263232,155078,1,0,8.5,1,Biweekly,0.847,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,8,29.0,6.6,None,10.7,6.4,0,1,29.3,1,0,50.3,127.8,138.2,0,N/A,0,84.4,79.5,2.14,186.1,935.3,0.207,2.36,10.58,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,36.1,52.7,80.4,10,2,0,Disability,1 |
| HC003-0000146,1.06,Male,White_non_Hispanic,US,Middle,B,Severe,0.1,Nonsense,0,1,Secondary,Recombinant_SHL,34.1,Biweekly_EHL,1.0,14.1,0.737,162704,454990,0,0,27.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,27,20.9,19.9,Mild,0.7,20.1,1,0,71.4,0,0,50.8,111.5,143.0,0,N/A,0,25.0,159.9,3.23,105.5,610.7,0.067,1.87,9.05,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,9,40.5,69.0,29.5,5,12,2,Disability,3 |
| HC003-0000147,1.51,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Large_deletion,1,1,Secondary,Recombinant_SHL,29.3,3x_week,5.5,10.8,0.738,160405,110152,1,0,1.0,1,Weekly,0.752,0,0,0,1,19.7,High_titer,16,1,0,N/A,0,0,aPCC,0,4,3,0,0,0,0,0,1,14,18.5,24.4,None,11.8,4.0,0,0,40.5,1,0,14.6,113.0,114.9,0,N/A,0,83.0,58.2,2.55,117.6,795.3,0.253,15.05,10.06,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,44.5,49.0,78.7,5,7,12,Employed_full,0 |
| HC003-0000148,0.94,Male,Hispanic,Other,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_EHL,35.8,Every_other_day,21.1,17.0,0.653,178308,222642,0,0,25.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,1,30,14.9,2.8,None,10.5,11.3,0,0,16.7,0,0,47.4,63.8,107.8,0,N/A,0,69.0,67.1,1.53,128.5,743.2,0.142,3.26,6.34,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,5,29.0,49.6,62.4,2,1,7,Employed_full,2 |
| HC003-0000149,1.23,Male,White_non_Hispanic,Europe,High,B,Severe,0.1,Missense,0,1,Primary,Non_factor,23.5,3x_week,10.4,27.2,0.77,313090,189617,1,0,24.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,21,9.4,12.0,Mild,28.9,10.4,0,1,38.6,0,0,54.1,98.6,145.0,1,50.0,0,69.4,77.4,2.44,154.4,667.2,0.246,0.73,10.06,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,29.0,53.8,28.0,7,8,5,Employed_full,0 |
| HC003-0000150,0.06,Male,White_non_Hispanic,US,Low,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,28.9,Weekly_EHL,13.3,18.0,0.692,366547,310657,0,0,42.2,1,Weekly,0.763,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,0,6,1.6,9.5,Mild,18.9,0.0,0,0,21.8,1,0,41.8,118.3,109.3,0,N/A,1,46.5,78.8,2.38,77.4,787.0,0.365,5.51,4.16,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,49.5,54.2,66.7,8,11,4,Employed_part,0 |
| HC003-0000151,3.18,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Small_indel,0,1,Secondary,Recombinant_SHL,22.8,3x_week,8.9,16.5,0.676,114838,208508,0,0,30.5,0,N/A,0.0,0,0,0,1,2.1,Low_titer,18,0,0,N/A,0,0,aPCC,0,3,2,0,0,0,0,0,0,3,18.0,15.7,None,5.3,7.9,1,0,35.7,0,0,36.0,99.7,145.0,0,N/A,0,60.2,107.5,3.0,151.0,511.8,0.126,2.36,2.84,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,18,32.5,47.4,59.8,0,3,3,Disability,0 |
| HC003-0000152,5.02,Male,White_non_Hispanic,Europe,Middle,A,Mild,26.8,Intron22_inversion,1,1,Primary,Recombinant_SHL,31.2,Every_other_day,1.3,14.4,0.727,198313,144980,0,0,22.4,1,Weekly,0.855,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,10,8.5,12.8,Mild,8.9,4.7,0,0,17.2,1,0,25.7,88.5,111.2,0,N/A,0,59.5,82.9,2.32,70.0,475.6,0.156,4.33,38.98,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,54.1,49.6,55.7,2,11,9,Disability,0 |
| HC003-0000153,1.16,Male,Black_non_Hispanic,US,Low,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,22.8,3x_week,17.6,12.1,0.48,310510,185978,0,0,34.3,0,N/A,0.0,1,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,1,13,9.9,8.9,None,9.8,12.1,0,0,24.1,1,0,24.8,124.6,118.1,0,N/A,0,39.9,94.4,2.31,80.5,727.9,0.084,3.61,10.74,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,20.5,66.7,58.2,4,7,6,Employed_full,1 |
| HC003-0000154,6.81,Male,White_non_Hispanic,US,Middle,B,Mild,34.73,Nonsense,0,0,None_on_demand,Non_factor,22.5,Every_other_day,1.0,23.9,0.526,156403,187341,0,0,24.5,0,N/A,0.0,0,1,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,5,35.6,12.8,Mild,43.9,18.4,0,0,41.8,1,0,43.9,140.0,121.6,1,51.9,0,72.9,76.2,3.33,95.4,355.2,0.2,14.76,37.54,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,3,50.3,50.7,61.7,12,7,0,Disability,2 |
| HC003-0000155,0.34,Male,Hispanic,Europe,Middle,A,Mild,16.58,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,31.3,3x_week,8.7,23.9,0.929,348134,171811,0,0,12.5,0,N/A,0.0,1,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,37,28,0,0,0,0,0,1,18,14.4,10.3,Moderate,56.0,5.9,1,0,11.8,1,0,39.2,100.6,97.3,1,67.6,0,99.6,86.7,1.87,131.8,742.1,0.141,3.3,5.77,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.1,61.0,61.7,4,11,8,Disability,1 |
| HC003-0000156,5.57,Male,Asian,Latin_America,Middle,A,Severe,0.1,Small_indel,0,1,Secondary,Recombinant_SHL,26.9,Every_other_day,11.7,8.0,0.713,223137,93008,0,0,4.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,17,0.0,24.7,Moderate,10.1,5.9,0,1,1.9,1,0,39.0,132.5,97.3,0,N/A,0,33.7,98.3,2.8,81.8,446.9,1.674,8.61,64.69,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,7,39.0,46.9,41.3,0,7,10,Employed_full,1 |
| HC003-0000157,0.73,Male,White_non_Hispanic,US,Middle,A,Mild,11.83,Small_indel,0,0,None_on_demand,Recombinant_SHL,12.6,Weekly_EHL,13.4,8.6,0.817,173850,334886,0,0,11.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,29,22,0,0,0,0,0,0,7,8.6,5.7,None,71.4,23.1,1,0,23.6,1,0,60.3,129.5,141.4,0,N/A,1,75.8,96.2,2.43,161.0,923.2,1.003,7.91,7.94,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,12,41.6,69.8,67.6,1,8,1,Employed_full,0 |
| HC003-0000158,1.34,Male,White_non_Hispanic,Asia_Pacific,High,A,Mild,14.28,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,16.4,3x_week,7.6,12.1,0.579,277042,306575,1,0,17.5,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,22,16,0,0,0,0,0,0,23,3.0,14.1,None,0.0,3.7,1,1,37.3,1,0,26.9,95.5,94.0,0,N/A,0,55.8,155.5,2.15,148.1,578.7,0.881,1.5,20.73,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,13,24.1,65.4,56.7,16,6,2,Disability,3 |
| HC003-0000159,4.87,Male,Asian,Asia_Pacific,Middle,B,Mild,14.55,Large_deletion,0,0,None_on_demand,Plasma_derived,18.8,Every_other_day,1.0,11.1,0.644,339547,106714,0,0,20.1,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,18,14,0,0,0,0,0,0,10,13.3,16.1,Moderate,16.7,0.0,0,0,26.1,1,0,37.9,100.4,145.0,0,N/A,0,53.2,99.2,2.08,96.6,911.6,0.107,5.21,7.61,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,52.3,55.1,84.2,5,0,2,Disability,3 |
| HC003-0000160,0.25,Male,Asian,Asia_Pacific,High,B,Severe,0.1,Other,0,1,Secondary,Recombinant_SHL,20.9,3x_week,7.2,8.0,0.854,161278,154761,0,1,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,12,9,0,0,0,0,0,0,13,0.0,15.5,None,26.4,16.3,0,0,21.4,1,1,62.3,140.0,123.3,1,38.4,0,66.6,94.1,3.08,56.4,612.1,0.261,2.44,8.57,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,17,35.3,62.4,74.0,2,8,3,Disability,2 |
| HC003-0000161,0.38,Female,Hispanic,US,Middle,A,Severe,0.1,Missense,0,1,Primary,Recombinant_EHL,31.3,3x_week,7.5,18.3,0.607,231986,160726,0,0,15.4,1,Monthly,0.89,0,0,0,1,5.0,High_titer,5,0,1,Low_dose,0,23,Emicizumab_bypass,0,3,2,0,0,0,0,0,0,6,20.2,9.6,Severe,28.7,7.7,0,0,58.7,0,0,38.3,92.7,106.5,0,N/A,1,67.0,30.1,2.63,135.0,604.4,0.115,1.7,6.66,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,30.8,71.2,75.6,0,7,12,Employed_part,2 |
| HC003-0000162,2.69,Male,Black_non_Hispanic,US,Middle,A,Severe,0.1,Missense,0,1,Primary,Recombinant_EHL,29.8,Weekly_EHL,7.4,12.3,0.637,355261,100885,0,0,18.3,0,N/A,0.0,0,0,0,1,0.1,Low_titer,33,0,0,N/A,0,0,aPCC,0,0,0,0,0,0,0,0,1,4,11.4,22.9,Moderate,11.8,9.7,1,0,28.3,1,1,42.8,102.8,132.6,0,N/A,0,69.1,106.7,2.7,11.2,805.9,1.316,1.71,4.74,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,4,63.8,46.0,88.1,7,4,4,Employed_full,1 |
| HC003-0000163,1.96,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Mild,20.65,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,36.5,Biweekly_EHL,17.8,8.5,0.726,169863,70728,0,0,24.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,50,38,0,0,0,0,0,1,9,9.3,0.0,None,75.7,21.4,0,1,3.6,1,0,39.9,140.0,80.7,0,N/A,0,40.1,44.7,2.84,124.7,702.7,0.586,8.65,17.85,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,8,36.2,45.4,72.3,8,0,5,Disability,2 |
| HC003-0000164,0.58,Male,White_non_Hispanic,US,Middle,A,Mild,16.41,Small_indel,0,0,None_on_demand,Recombinant_EHL,34.0,Every_other_day,4.7,12.2,0.737,99245,128631,0,0,37.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,21,16,0,0,0,0,0,0,24,16.8,3.2,Moderate,41.8,0.0,0,0,30.6,1,0,50.5,103.6,119.0,0,N/A,0,89.0,115.4,2.57,62.0,638.0,0.13,37.13,7.33,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,30.5,59.7,60.0,9,8,6,Employed_full,1 |
| HC003-0000165,0.89,Male,Black_non_Hispanic,Europe,Middle,A,Mild,14.49,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,36.6,Weekly_EHL,13.8,19.6,0.558,106730,150512,0,0,20.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,21,16,0,0,0,0,0,0,6,14.1,17.3,None,30.6,6.8,0,0,34.5,1,0,17.3,140.0,121.3,0,N/A,0,66.8,104.0,1.87,145.3,577.3,0.405,2.35,15.6,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,48.9,43.1,26.2,21,3,15,Disability,1 |
| HC003-0000166,1.5,Female,White_non_Hispanic,Latin_America,Middle,A,Mild,27.7,Other,0,1,Secondary,Recombinant_SHL,32.9,Weekly_EHL,12.9,10.2,0.659,208808,87499,0,0,7.1,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,11,13.4,5.0,None,3.6,0.6,0,0,43.4,1,0,39.6,94.6,102.2,0,N/A,0,78.1,122.3,1.61,39.6,579.0,0.092,5.33,16.67,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.9,40.5,65.4,1,1,5,Employed_full,2 |
| HC003-0000167,3.8,Male,Black_non_Hispanic,US,Low,A,Mild,6.86,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,29.7,Weekly_EHL,17.8,15.6,0.341,121656,196514,0,0,1.0,0,N/A,0.0,0,0,0,1,144.8,High_titer,13,1,1,Malmö,1,13,rFVIIa,0,7,5,0,0,0,0,0,0,13,12.3,4.5,Severe,76.5,10.0,0,0,19.8,1,1,42.7,117.8,113.6,1,42.4,0,91.7,82.2,3.17,68.5,1074.4,0.27,5.75,26.39,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Surgical_complication,0,0,51.1,40.0,86.2,5,1,19,Employed_full,2 |
| HC003-0000168,0.72,Male,White_non_Hispanic,Latin_America,Middle,A,Mild,16.91,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,36.8,3x_week,11.2,23.6,0.729,217807,321717,1,0,26.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,15,11,0,0,0,0,0,0,10,14.8,8.3,Moderate,3.6,4.7,0,1,27.6,0,0,30.0,136.7,145.0,0,N/A,0,25.0,100.8,2.5,112.5,348.4,0.262,2.93,10.79,1,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.9,57.5,74.5,8,0,6,Unemployed,0 |
| HC003-0000169,1.53,Male,Black_non_Hispanic,Other,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_EHL,35.4,3x_week,16.7,21.4,0.651,728662,274048,0,0,7.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,1,0,0,0,22,19.1,5.7,Mild,9.0,1.0,0,1,12.8,0,0,46.1,105.7,128.3,0,N/A,0,78.9,118.9,2.44,119.1,433.5,0.544,13.82,1.9,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,50.5,35.6,54.9,5,8,4,Employed_full,4 |
| HC003-0000170,0.71,Male,White_non_Hispanic,Latin_America,Middle,A,Mild,29.14,Intron22_inversion,1,0,None_on_demand,Plasma_derived,31.0,Every_other_day,11.0,12.0,0.844,117341,168832,1,0,28.4,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,41,31,0,0,0,0,0,0,15,17.6,17.1,Moderate,2.3,12.4,1,0,54.9,0,1,51.4,117.0,132.2,0,N/A,0,61.4,74.0,3.3,70.0,861.8,0.664,25.99,5.54,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,62.6,52.0,62.8,0,15,13,Employed_full,0 |
| HC003-0000171,0.61,Male,White_non_Hispanic,Europe,High,B,Severe,0.1,Missense,0,1,Primary,Recombinant_SHL,38.2,Biweekly_EHL,14.6,12.3,0.863,226486,71668,1,0,34.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,6,28.5,19.2,None,19.3,8.1,0,0,15.9,0,0,47.4,129.9,110.8,0,N/A,0,87.4,117.1,1.87,81.7,848.3,0.306,2.78,7.22,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Surgical_complication,1,20,31.7,21.7,54.2,10,4,2,Employed_full,0 |
| HC003-0000172,4.27,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Small_indel,0,1,Tertiary,Recombinant_SHL,10.0,3x_week,3.0,13.2,0.753,964517,257262,1,0,1.0,0,N/A,0.0,0,0,1,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,1,0,0,17,8.4,12.7,Moderate,25.1,0.5,0,1,31.2,1,0,63.4,97.0,101.2,1,47.9,0,47.4,115.8,1.14,133.1,483.9,0.252,17.95,7.47,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,35.0,60.4,66.3,4,9,16,Employed_full,1 |
| HC003-0000173,1.11,Male,White_non_Hispanic,Europe,High,A,Moderate,2.82,Large_deletion,1,1,Secondary,Plasma_derived,25.7,3x_week,1.0,10.4,0.815,342792,193532,0,0,24.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,11,17.9,20.4,Severe,0.7,0.9,0,0,31.8,1,1,36.8,140.0,120.7,0,N/A,0,85.6,96.2,1.49,135.3,334.6,0.023,2.89,24.2,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,22.4,61.0,54.9,2,6,13,Employed_full,0 |
| HC003-0000174,2.68,Male,Black_non_Hispanic,Latin_America,Middle,B,Mild,11.15,Missense,0,0,None_on_demand,Recombinant_SHL,25.6,3x_week,14.3,9.2,0.528,215209,222387,1,0,33.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,16,12,0,0,0,0,1,0,8,44.4,0.9,Moderate,78.0,9.2,0,1,3.6,1,0,48.0,135.8,80.8,1,46.0,1,41.8,144.2,2.13,80.9,879.0,1.051,2.06,20.54,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,44.2,53.9,82.2,3,7,8,Employed_full,0 |
| HC003-0000175,0.61,Male,White_non_Hispanic,Asia_Pacific,High,B,Severe,0.1,Splice_site,0,1,Primary,Recombinant_EHL,37.2,Every_other_day,14.6,22.0,0.622,244231,473568,1,0,30.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,7,14.5,12.6,Mild,12.0,0.0,1,1,25.2,0,0,47.7,107.9,105.3,0,N/A,0,73.8,114.4,2.46,70.7,461.6,0.178,4.01,6.49,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,12,41.4,67.8,63.7,15,6,5,Unemployed,3 |
| HC003-0000176,0.37,Male,White_non_Hispanic,Latin_America,High,A,Moderate,3.47,Intron22_inversion,1,1,Primary,Plasma_derived,40.6,Every_other_day,14.9,10.7,0.836,347187,119085,1,1,1.0,0,N/A,0.0,0,1,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,12,15.0,22.8,None,66.8,9.4,1,0,37.0,0,0,39.2,110.3,102.5,1,62.6,0,71.3,53.1,3.1,40.2,561.6,0.327,8.98,65.83,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,53.9,64.0,65.6,13,9,11,Employed_full,0 |
| HC003-0000177,2.28,Male,White_non_Hispanic,US,Low,A,Severe,0.1,Large_deletion,1,0,None_on_demand,Recombinant_SHL,16.4,3x_week,8.9,16.7,0.621,742266,42727,0,0,7.8,1,Biweekly,0.804,0,0,0,1,112.8,High_titer,8,1,0,N/A,0,0,rFVIIa,0,0,0,0,0,0,0,0,0,19,0.0,19.8,Moderate,8.2,16.0,0,0,31.9,1,0,55.6,140.0,88.3,0,N/A,0,61.6,127.7,2.82,105.1,667.3,1.835,4.12,5.4,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,39.7,48.1,50.4,2,1,10,Employed_full,3 |
| HC003-0000178,2.83,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Missense,0,1,Primary,Non_factor,39.3,3x_week,20.9,21.5,0.448,195143,106221,0,1,2.6,1,Monthly,0.913,0,0,0,1,16.5,High_titer,34,0,1,Low_dose,1,25,rFVIIa,0,0,0,0,0,0,0,0,0,13,6.4,23.5,None,18.3,12.0,0,1,44.1,0,0,45.5,107.9,136.7,0,N/A,0,42.3,81.6,1.12,127.5,456.9,0.116,8.09,5.81,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.1,47.2,56.2,0,6,8,Employed_full,0 |
| HC003-0000179,1.9,Male,Asian,US,Low,A,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_SHL,18.6,Weekly_EHL,9.2,11.8,0.614,170320,229354,0,1,24.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,39,29,0,0,0,0,0,1,9,13.7,7.3,Severe,30.7,4.3,0,0,23.3,0,0,27.6,105.6,122.7,0,N/A,0,56.9,122.3,3.8,101.1,816.4,0.306,5.37,2.76,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.2,64.8,45.8,11,11,7,Unemployed,3 |
| HC003-0000180,2.37,Male,White_non_Hispanic,Europe,High,A,Mild,12.73,Large_deletion,1,0,None_on_demand,Recombinant_SHL,18.9,Weekly_EHL,14.5,18.0,0.637,117326,182310,0,0,23.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,22,16,0,0,0,0,0,0,7,21.4,19.3,None,48.7,9.6,0,0,53.6,0,0,51.0,137.9,113.8,1,59.0,0,85.3,108.3,2.19,58.0,653.8,0.448,13.23,1.82,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,37.4,62.8,81.8,17,9,7,Employed_full,0 |
| HC003-0000181,2.04,Male,Other,Europe,Middle,A,Mild,12.02,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,26.1,3x_week,15.6,11.4,0.585,285460,97947,1,0,1.0,1,Weekly,0.879,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,7,5,0,0,0,0,0,0,4,22.8,8.6,None,78.0,0.5,0,0,36.1,0,0,36.0,87.0,137.1,0,N/A,1,97.7,30.0,3.01,166.5,491.2,0.722,6.85,2.55,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,44.0,53.3,54.8,19,7,8,Employed_full,0 |
| HC003-0000182,2.18,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,25.5,Weekly_EHL,22.3,13.7,0.586,115449,88445,0,0,14.4,0,N/A,0.0,0,0,0,1,25.7,High_titer,7,1,1,High_dose,1,17,aPCC,0,1,1,0,0,0,0,0,0,19,18.9,16.8,None,10.0,8.8,0,0,39.6,1,0,38.1,113.4,95.4,0,N/A,0,108.0,116.9,2.67,10.9,507.1,0.301,15.25,18.4,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.5,38.4,64.2,0,6,6,Employed_part,1 |
| HC003-0000183,4.51,Male,Hispanic,Europe,High,A,Severe,0.1,Missense,0,1,Primary,Plasma_derived,15.5,Every_other_day,10.1,13.9,0.895,203156,150647,1,0,27.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,10,24.6,22.5,Mild,24.6,6.0,1,0,26.5,1,0,39.0,116.7,100.8,0,N/A,0,76.6,93.8,2.4,130.1,883.5,0.771,2.26,14.4,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Liver_failure_HCV,0,0,45.9,65.3,40.3,14,5,2,Disability,4 |
| HC003-0000184,5.65,Male,White_non_Hispanic,Latin_America,Low,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_EHL,33.2,Weekly_EHL,8.1,20.2,0.498,155560,96467,0,0,19.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,14,3.0,5.6,None,0.0,1.8,0,1,43.4,1,0,50.8,100.9,145.0,0,N/A,0,70.5,87.1,2.28,103.7,599.8,0.216,3.81,3.34,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,37.5,56.7,44.8,7,5,1,Employed_full,0 |
| HC003-0000185,1.32,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_SHL,33.4,Weekly_EHL,3.0,12.9,0.645,511178,233355,0,0,19.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,27,20.9,0.0,None,18.1,11.7,0,0,4.9,1,1,54.9,83.7,145.0,0,N/A,1,74.9,88.2,1.84,113.7,760.6,0.465,4.48,8.08,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,46.1,55.4,58.5,0,0,8,Employed_full,1 |
| HC003-0000186,0.18,Male,Asian,US,Middle,B,Moderate,2.84,Missense,0,1,Tertiary,Recombinant_SHL,36.4,Every_other_day,21.3,12.6,0.656,197790,146428,0,0,13.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,24,15.2,26.8,Severe,1.4,0.0,0,0,37.9,0,1,40.1,116.4,137.3,0,N/A,0,107.4,122.1,1.76,63.5,648.2,0.419,2.26,15.27,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,11,46.8,27.6,57.6,3,8,1,Employed_full,3 |
| HC003-0000187,2.81,Male,Other,Latin_America,Low,C,Mild,5.03,N/A,0,0,None_on_demand,Plasma_derived,24.5,Every_other_day,14.5,12.3,0.625,340496,131458,1,0,5.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,29,22,1,3,0,0,0,0,8,16.5,15.9,None,27.8,0.9,0,1,36.2,0,0,39.4,128.8,133.5,0,N/A,1,76.5,74.2,2.32,88.9,334.2,0.28,2.0,1.19,0,1,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,36.4,61.3,65.4,3,11,6,Disability,3 |
| HC003-0000188,1.69,Male,Asian,Latin_America,Middle,B,Mild,21.58,Missense,0,1,Tertiary,Recombinant_EHL,27.7,Every_other_day,14.7,12.5,0.448,102492,123113,1,0,17.8,0,N/A,0.0,1,1,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,10,10.7,11.1,Mild,30.5,1.6,1,1,2.4,1,0,17.4,101.4,114.5,1,50.6,1,66.9,131.2,1.71,106.7,784.4,0.39,6.08,36.42,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,39.1,55.4,90.2,9,7,2,Employed_part,0 |
| HC003-0000189,4.88,Male,White_non_Hispanic,Europe,High,A,Severe,0.1,Small_indel,0,1,Primary,Plasma_derived,27.8,Every_other_day,30.7,13.0,0.632,290368,205163,0,0,18.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,1,0,0,2,3.6,10.7,Mild,0.0,5.0,1,1,36.0,1,0,33.5,91.4,114.9,0,N/A,0,58.9,57.4,3.22,91.6,843.3,0.15,7.63,19.05,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,17,38.1,50.6,33.8,0,6,11,Unemployed,2 |
| HC003-0000190,2.09,Male,White_non_Hispanic,US,Low,B,Moderate,1.52,Missense,0,1,Primary,Recombinant_EHL,41.5,3x_week,14.0,13.5,0.645,130366,183745,0,0,25.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,16,0.4,0.0,Mild,14.4,15.8,0,0,29.7,0,0,30.6,140.0,129.1,0,N/A,0,61.5,108.3,2.45,23.2,981.6,0.237,4.9,15.32,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,26.5,47.6,75.7,12,8,3,Employed_full,2 |
| HC003-0000191,0.28,Male,Hispanic,Latin_America,Middle,A,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_SHL,10.0,Every_other_day,4.2,15.6,0.582,207858,198984,0,0,26.4,1,Biweekly,0.89,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,13,18.8,13.7,Mild,9.4,12.5,0,0,21.1,0,0,45.7,125.6,145.0,0,N/A,0,73.5,121.6,3.45,163.5,307.9,0.108,10.46,21.8,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.7,57.1,69.0,9,0,0,Employed_full,2 |
| HC003-0000192,2.1,Male,White_non_Hispanic,Other,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,20.3,Weekly_EHL,10.8,12.9,0.81,1011274,196824,0,0,19.0,0,N/A,0.0,0,0,0,1,60.0,High_titer,22,1,1,Low_dose,0,28,rFVIIa,0,2,2,0,0,0,0,0,1,13,21.0,7.8,Moderate,17.3,8.6,1,1,21.7,0,0,40.7,107.8,132.7,0,N/A,0,48.5,120.9,2.18,121.0,81.5,0.212,1.85,1.18,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,9,48.4,60.7,53.3,12,4,11,Disability,0 |
| HC003-0000193,1.14,Male,Black_non_Hispanic,Latin_America,Middle,B,Mild,6.36,Missense,0,1,Tertiary,Recombinant_SHL,28.0,Every_other_day,6.2,14.6,0.712,469444,173495,0,0,31.1,0,N/A,0.0,0,0,0,1,2.9,Low_titer,21,0,0,N/A,0,0,rFVIIa,0,4,3,0,0,0,0,0,0,23,13.4,12.4,Mild,3.1,8.3,0,0,6.0,1,0,31.1,133.4,142.2,0,N/A,0,51.2,105.2,2.1,96.4,765.0,0.749,3.28,6.07,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,49.3,52.2,55.9,4,6,12,Employed_full,1 |
| HC003-0000194,0.23,Male,Hispanic,Asia_Pacific,Low,A,Mild,14.55,Small_indel,0,0,None_on_demand,Recombinant_SHL,19.3,Every_other_day,9.6,9.4,0.522,248439,107305,1,0,13.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,44,33,0,0,1,0,0,0,9,14.8,12.2,Mild,64.3,7.9,1,0,13.6,1,0,43.8,119.8,108.5,0,N/A,0,63.6,94.2,2.7,99.0,542.1,0.422,1.74,22.93,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,43.7,61.6,77.7,9,0,7,Employed_full,1 |
| HC003-0000195,0.55,Male,Hispanic,Other,High,A,Mild,39.82,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,25.9,3x_week,9.6,11.2,0.505,1829156,124843,0,0,1.0,1,Biweekly,0.806,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,17,6.4,0.0,None,0.0,16.2,0,1,17.4,1,0,41.2,140.0,136.1,0,N/A,0,55.1,84.6,2.27,162.3,392.6,0.385,5.01,7.34,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,28.9,44.5,61.1,2,7,9,Disability,0 |
| HC003-0000196,6.95,Male,Asian,Europe,High,A,Mild,37.14,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,27.0,Every_other_day,8.5,12.0,0.818,154956,147659,1,0,23.7,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,17,13,1,1,0,0,0,0,17,21.0,15.9,Mild,0.0,0.0,0,0,27.7,1,0,11.5,128.3,112.9,0,N/A,1,78.1,65.8,2.89,65.3,669.4,0.084,6.62,14.42,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,50.8,49.5,57.5,10,0,0,Employed_full,0 |
| HC003-0000197,0.81,Male,Black_non_Hispanic,Europe,Low,B,Mild,12.53,Missense,0,0,None_on_demand,Recombinant_SHL,22.7,Biweekly_EHL,3.6,16.5,0.702,539895,505143,0,0,19.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,27,20,1,1,0,0,0,0,8,15.7,13.5,None,65.1,12.6,0,1,17.9,1,0,55.3,87.2,127.5,0,N/A,0,79.8,80.8,3.12,56.3,569.1,0.389,13.11,27.2,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,14,60.4,62.9,47.3,6,9,2,Employed_full,0 |
| HC003-0000198,0.52,Male,White_non_Hispanic,Europe,Middle,A,Mild,15.85,Large_deletion,1,0,None_on_demand,Recombinant_SHL,28.5,3x_week,21.6,9.7,0.793,106980,91636,0,0,24.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,23,17,0,0,0,0,0,0,5,10.6,14.6,Mild,17.0,5.0,0,0,32.6,1,0,54.1,101.8,136.1,0,N/A,0,70.8,73.1,2.95,129.0,420.3,0.286,1.75,13.92,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,46.5,52.0,50.3,6,7,8,Employed_full,1 |
| HC003-0000199,0.89,Male,White_non_Hispanic,Other,Middle,A,Severe,0.1,Intron22_inversion,1,1,Tertiary,Recombinant_SHL,33.0,Every_other_day,13.8,10.5,0.598,231804,145876,0,0,2.8,0,N/A,0.0,1,0,0,1,17.7,High_titer,21,1,1,Malmö,1,25,rFVIIa,0,1,1,0,0,0,0,0,1,4,25.4,10.5,Mild,28.5,11.0,1,0,46.2,1,1,39.1,102.8,115.4,1,37.4,0,75.8,68.5,3.08,113.5,635.1,0.463,6.04,5.86,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,8,40.0,73.2,45.0,7,5,2,Disability,0 |
| HC003-0000200,4.13,Male,Hispanic,US,Middle,B,Severe,0.1,Missense,0,1,Primary,Recombinant_SHL,26.1,Every_other_day,10.6,18.0,0.477,119530,188930,0,0,39.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,12,22.7,12.4,Moderate,44.9,11.0,1,0,31.0,0,0,46.2,121.2,106.7,0,N/A,1,67.6,150.5,2.81,54.6,752.0,0.911,14.14,12.41,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Other,1,14,30.5,58.8,74.4,0,9,5,Disability,1 |
| HC003-0000201,2.18,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Missense,0,1,Primary,Recombinant_SHL,24.4,3x_week,16.5,12.3,0.566,313127,154559,1,0,26.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,1,15,0.0,13.4,Mild,12.1,12.4,1,1,13.1,1,0,38.1,108.9,131.5,0,N/A,0,25.0,51.9,2.13,138.5,681.5,0.217,2.01,1.64,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,13,39.8,44.3,51.0,13,7,6,Employed_part,1 |
| HC003-0000202,0.4,Male,White_non_Hispanic,Asia_Pacific,Low,A,Severe,0.1,Intron22_inversion,1,1,Primary,Plasma_derived,26.7,3x_week,14.8,17.5,0.531,277502,307732,0,0,14.5,1,Biweekly,0.804,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,1,3,15.6,14.2,Mild,37.6,17.5,1,0,20.7,0,1,22.7,92.5,122.6,0,N/A,1,45.7,131.5,2.97,106.8,682.9,0.234,1.67,11.49,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,3,34.6,40.3,45.3,7,8,9,Disability,1 |
| HC003-0000203,0.02,Male,White_non_Hispanic,US,Low,A,Severe,0.1,Missense,0,1,Secondary,Recombinant_SHL,27.9,Weekly_EHL,13.7,12.6,0.284,223106,154161,0,0,6.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,19,3.5,15.8,None,17.9,0.0,0,0,18.9,1,0,65.0,126.8,127.5,0,N/A,0,80.6,65.4,2.75,59.1,729.8,0.628,1.38,14.51,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,37.8,63.8,64.4,13,7,4,Employed_full,1 |
| HC003-0000204,0.88,Female,Black_non_Hispanic,Latin_America,High,B,Severe,0.1,Missense,0,1,Secondary,Plasma_derived,14.1,3x_week,16.1,12.7,0.783,516709,159968,0,0,30.9,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,9,7,0,0,0,0,0,1,7,16.7,14.3,Moderate,2.9,14.0,0,0,44.7,0,0,51.0,135.0,136.8,0,N/A,0,46.5,71.4,2.09,114.6,345.6,0.186,7.39,8.46,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,54.2,49.9,50.6,13,3,11,Employed_part,2 |
| HC003-0000205,0.3,Male,Asian,Europe,Middle,A,Mild,21.23,Missense,0,0,None_on_demand,Recombinant_SHL,31.7,3x_week,12.8,11.1,0.633,190945,270307,0,0,4.8,1,Biweekly,0.844,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,18,0.0,26.8,Severe,51.2,7.6,1,0,37.4,1,1,53.3,112.9,145.0,0,N/A,0,83.8,70.9,2.15,108.6,640.8,0.323,2.51,21.02,0,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,49.7,65.2,83.7,3,12,9,Employed_part,0 |
| HC003-0000206,4.13,Male,Hispanic,Other,High,A,Mild,34.55,Small_indel,0,1,Secondary,Recombinant_SHL,24.4,3x_week,16.0,14.8,0.659,326476,444789,0,0,45.1,1,Biweekly,0.892,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,6,17.4,6.2,Mild,18.6,5.2,0,0,70.5,0,0,38.6,119.2,136.9,0,N/A,1,85.1,68.9,2.35,91.5,693.2,0.061,6.57,9.49,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,36.2,50.6,62.6,6,11,13,Employed_full,0 |
| HC003-0000207,0.21,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Moderate,2.59,Missense,0,0,None_on_demand,Recombinant_SHL,38.1,Weekly_EHL,16.5,16.1,0.228,439034,363578,1,0,10.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,17,13,0,0,0,0,0,0,25,23.5,9.0,None,13.4,20.2,1,0,64.8,1,0,55.5,95.6,134.6,0,N/A,0,59.2,125.8,2.96,110.4,582.0,0.235,3.77,8.43,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,41.0,58.4,64.9,0,8,14,Employed_part,1 |
| HC003-0000208,1.37,Male,White_non_Hispanic,US,High,B,Severe,0.1,Other,0,1,Secondary,Recombinant_SHL,32.7,3x_week,13.0,8.9,0.569,110202,167992,0,0,38.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,3,13.7,25.5,Mild,0.0,12.2,0,0,20.4,1,1,25.6,104.5,116.0,0,N/A,0,52.0,116.5,2.46,120.0,500.7,0.856,18.93,38.44,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,1,39.9,52.6,64.9,13,7,10,Employed_part,0 |
| HC003-0000209,2.04,Male,Hispanic,Latin_America,Low,A,Mild,33.09,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,37.4,Every_other_day,10.7,16.5,0.678,171262,175473,0,0,15.8,0,N/A,0.0,0,0,0,1,14.0,High_titer,19,1,0,N/A,0,0,aPCC,0,29,22,0,0,0,0,0,0,4,1.0,10.8,None,26.9,5.5,0,1,17.3,0,0,39.1,105.4,118.8,0,N/A,0,65.2,93.5,2.4,131.6,515.7,0.394,8.42,3.12,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,21,35.2,58.6,70.0,9,9,7,Unemployed,0 |
| HC003-0000210,5.74,Male,White_non_Hispanic,US,Low,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,19.9,Weekly_EHL,21.2,14.7,0.851,277151,184123,1,0,37.0,1,Biweekly,0.753,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,1,22,38.5,19.5,Mild,25.1,13.7,0,0,41.2,1,0,50.9,126.2,133.2,0,N/A,0,64.0,175.8,2.32,99.3,597.2,0.618,2.36,25.87,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,25.2,63.3,71.9,8,11,1,Disability,1 |
| HC003-0000211,0.58,Male,Hispanic,Europe,High,C,Severe,0.1,N/A,0,1,Secondary,Recombinant_EHL,25.0,Weekly_EHL,9.1,25.1,0.342,391638,193590,0,0,9.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,1,14,28.9,13.1,None,45.5,7.7,1,0,10.9,0,0,34.5,120.1,118.5,0,N/A,0,78.8,99.5,2.22,84.2,814.6,0.647,3.52,24.09,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,5,49.1,56.2,62.4,6,14,6,Employed_full,0 |
| HC003-0000212,3.47,Male,Hispanic,Latin_America,High,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,18.1,3x_week,14.3,10.5,0.743,629539,117751,0,0,18.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,1,14,8.6,10.2,Mild,14.6,5.4,0,0,39.5,0,0,52.9,108.4,133.1,0,N/A,0,25.0,101.7,1.82,104.6,924.9,0.886,8.42,15.81,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,18,53.0,62.6,47.8,2,4,11,Employed_full,0 |
| HC003-0000213,1.53,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,22.4,Biweekly_EHL,14.5,15.0,0.59,235737,287304,1,0,27.7,0,N/A,0.0,0,0,0,1,1.9,Low_titer,41,1,0,N/A,0,0,rFVIIa,0,3,2,0,0,0,0,0,0,3,11.9,19.9,Moderate,0.0,4.4,0,0,24.2,1,1,45.6,107.6,110.3,0,N/A,0,48.9,80.8,2.8,142.6,888.2,0.228,1.91,5.13,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,33.3,39.0,59.8,13,10,4,Disability,0 |
| HC003-0000214,3.46,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Missense,0,1,Secondary,Plasma_derived,38.0,Weekly_EHL,8.3,15.3,0.808,221930,199447,1,0,25.9,0,N/A,0.0,0,0,0,1,97.7,High_titer,17,0,1,Malmö,1,14,rFVIIa,0,2,2,0,0,0,0,0,1,13,0.0,16.1,None,0.0,9.8,0,0,20.7,1,0,44.5,75.6,145.0,0,N/A,0,42.7,77.5,1.89,120.2,369.1,0.64,11.54,10.06,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,32.8,60.2,62.8,17,6,2,Unemployed,1 |
| HC003-0000215,0.72,Male,White_non_Hispanic,US,Middle,B,Mild,9.42,Missense,0,1,Secondary,Recombinant_SHL,39.9,Every_other_day,7.2,10.7,0.759,158965,175883,0,0,31.2,0,N/A,0.0,0,0,0,1,22.9,High_titer,12,0,0,N/A,0,0,rFVIIa,0,3,2,0,0,0,0,0,0,1,20.7,0.0,Mild,27.5,4.3,1,0,4.5,0,0,33.4,140.0,128.5,1,45.3,0,25.0,85.1,2.43,81.9,480.9,1.819,3.67,3.58,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,50.0,56.2,39.1,14,0,9,Employed_full,5 |
| HC003-0000216,0.67,Male,Asian,Latin_America,Middle,A,Mild,9.36,Large_deletion,1,0,None_on_demand,Recombinant_EHL,18.8,Weekly_EHL,9.9,21.2,0.576,327090,95266,0,0,12.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,10,8,0,0,0,0,0,1,0,0.0,13.4,None,34.2,8.9,0,0,46.6,0,0,46.9,73.3,127.3,0,N/A,0,54.1,123.8,2.2,97.2,768.3,0.295,8.56,4.46,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,32.7,53.4,32.5,6,9,17,Employed_part,0 |
| HC003-0000217,0.51,Male,Hispanic,Europe,Low,A,Mild,19.59,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,24.3,3x_week,9.0,20.3,0.488,224522,185562,1,0,19.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,11,8,0,0,0,0,0,0,6,23.0,4.0,None,1.4,13.3,0,0,5.5,1,0,65.0,123.4,116.3,0,N/A,0,32.0,116.0,2.78,161.6,884.1,0.105,3.83,8.32,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,24.7,32.1,45.0,9,12,13,Disability,1 |
| HC003-0000218,2.09,Male,White_non_Hispanic,Europe,High,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,27.4,3x_week,3.3,9.3,0.7,227654,69800,1,0,33.0,0,N/A,0.0,0,0,0,1,61.7,High_titer,13,1,0,N/A,0,0,Emicizumab_bypass,0,3,2,0,0,0,0,0,1,9,27.3,22.2,Mild,11.3,8.7,0,0,27.7,0,0,44.1,115.8,145.0,0,N/A,0,56.5,136.1,2.23,125.0,476.0,0.187,2.95,3.34,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,35.1,39.3,34.7,12,10,4,Employed_full,0 |
| HC003-0000219,1.3,Male,Asian,US,Middle,A,Mild,35.45,Large_deletion,1,0,None_on_demand,Recombinant_EHL,32.7,3x_week,8.1,20.7,0.53,253639,134481,1,1,9.5,1,Monthly,0.881,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,1,0,1,17,14.2,26.0,Moderate,33.0,19.9,0,0,22.0,0,0,48.7,109.7,102.4,0,N/A,0,54.3,79.9,1.9,101.1,683.0,0.438,2.59,5.99,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,54.9,58.3,55.2,7,5,7,Employed_full,7 |
| HC003-0000220,1.73,Male,White_non_Hispanic,US,Middle,A,Mild,35.87,Small_indel,0,1,Secondary,Recombinant_SHL,13.9,Weekly_EHL,13.6,12.1,0.371,373613,135734,1,0,24.9,1,Weekly,0.892,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,13,2.2,27.0,Moderate,16.7,8.1,0,1,14.3,0,0,50.4,114.8,112.3,0,N/A,0,75.0,116.5,2.89,140.6,446.3,0.08,17.92,2.74,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,34.2,59.5,51.2,17,8,11,Employed_part,0 |
| HC003-0000221,2.57,Male,White_non_Hispanic,Asia_Pacific,Low,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Plasma_derived,15.2,3x_week,19.6,9.1,0.676,191331,207627,0,1,15.4,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,3,30.0,14.9,None,8.1,16.1,0,0,21.5,0,1,28.3,101.7,140.4,1,54.2,0,59.5,108.6,1.99,73.3,699.8,0.164,3.54,13.3,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,32.9,60.1,63.2,13,9,7,Employed_full,0 |
| HC003-0000222,2.31,Male,Other,US,Low,A,Mild,8.76,Missense,0,0,None_on_demand,Recombinant_EHL,31.9,3x_week,15.3,24.5,0.826,168840,460434,1,0,20.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,25,19,0,0,0,0,0,0,11,15.0,8.3,None,49.6,13.9,1,0,25.2,1,1,40.4,128.1,129.3,0,N/A,0,27.8,112.2,2.48,108.2,534.2,0.231,52.69,32.18,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,34.8,55.9,71.9,21,8,3,Disability,4 |
| HC003-0000223,2.09,Male,White_non_Hispanic,Europe,Middle,B,Moderate,2.65,Missense,0,1,Primary,Recombinant_SHL,12.4,Every_other_day,1.0,8.8,0.544,347679,239415,1,0,19.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,1,0,13,16.1,14.6,Mild,3.5,17.2,0,0,38.9,1,0,40.0,88.7,114.6,0,N/A,0,72.6,75.8,3.04,170.0,682.9,0.329,5.06,53.37,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,6,27.3,44.0,66.1,8,11,13,Employed_full,0 |
| HC003-0000224,2.8,Male,White_non_Hispanic,Other,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Plasma_derived,24.4,3x_week,15.8,13.4,0.768,43676,371090,1,0,8.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,1,5,3.8,4.5,Mild,32.4,19.8,1,1,27.8,0,0,16.5,121.6,115.1,0,N/A,0,118.2,70.9,2.03,121.1,431.9,1.268,2.27,2.91,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,25.5,45.7,68.1,0,10,13,Unemployed,0 |
| HC003-0000225,0.07,Male,Hispanic,US,Middle,A,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_EHL,29.3,Biweekly_EHL,8.7,13.5,0.856,186800,248353,0,1,14.9,1,Biweekly,0.809,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,7,17.3,30.8,Moderate,0.0,0.0,0,0,55.0,0,0,51.5,101.4,119.8,0,N/A,0,88.7,115.1,2.35,159.8,355.9,0.522,1.26,3.41,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,1,HIV_AIDS,1,6,37.1,34.9,75.2,7,4,2,Unemployed,1 |
| HC003-0000226,3.01,Male,White_non_Hispanic,Latin_America,Low,A,Moderate,1.75,Intron22_inversion,1,1,Secondary,Non_factor,31.3,Weekly_EHL,14.7,19.8,0.529,134486,315693,0,1,19.7,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,12,12.6,21.6,Moderate,7.8,9.6,1,1,39.8,1,0,30.8,106.5,126.8,0,N/A,0,79.9,124.4,2.18,91.6,1207.7,0.124,12.02,7.06,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,24.6,57.2,57.4,5,6,7,Employed_full,3 |
| HC003-0000227,2.6,Male,Hispanic,US,High,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_EHL,26.9,Every_other_day,11.9,27.6,0.565,552360,455233,0,0,16.8,1,Biweekly,0.829,1,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,22,0.0,14.4,Moderate,19.6,7.3,1,0,16.3,0,0,50.2,107.0,145.0,0,N/A,0,60.7,82.7,2.47,76.0,662.5,6.646,3.84,15.49,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,35.6,75.1,25.5,8,4,6,Employed_full,1 |
| HC003-0000228,0.88,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,25.1,Weekly_EHL,10.8,13.3,0.773,205961,124752,0,0,36.9,1,Weekly,0.845,0,1,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,3,31.1,20.0,None,14.3,8.7,0,0,30.4,1,1,32.9,111.7,135.9,1,45.5,0,54.2,117.1,2.37,141.4,1034.2,0.297,8.66,6.8,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.9,55.1,37.6,16,7,15,Employed_full,2 |
| HC003-0000229,0.48,Male,White_non_Hispanic,Latin_America,High,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_EHL,34.8,Weekly_EHL,11.4,18.8,0.229,191678,120746,0,0,30.1,1,Weekly,0.99,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,35,36.1,8.1,Severe,28.1,5.6,0,1,9.3,1,0,65.0,125.0,143.4,0,N/A,0,52.7,133.6,2.86,21.9,921.6,0.079,28.73,19.49,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,44.1,48.4,69.0,4,0,10,Employed_part,0 |
| HC003-0000230,1.42,Male,White_non_Hispanic,Asia_Pacific,Low,A,Mild,25.1,Small_indel,0,0,None_on_demand,Recombinant_SHL,30.3,3x_week,11.9,12.1,0.77,260622,251301,0,0,21.5,1,Monthly,0.855,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,8,27.2,3.1,Severe,71.2,4.7,1,0,21.3,1,0,38.7,114.3,117.2,1,52.5,0,70.3,89.9,2.09,102.2,355.6,0.131,7.65,13.22,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,38.5,56.3,64.7,3,14,6,Employed_full,2 |
| HC003-0000231,4.05,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_SHL,22.8,Every_other_day,20.1,16.9,0.362,187733,179541,0,0,8.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,34,25.4,0.0,None,27.3,1.4,1,1,25.5,1,0,65.0,133.7,134.3,1,40.4,0,40.0,59.7,3.04,136.2,715.1,0.132,5.87,1.67,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,5,26.8,54.6,71.7,4,3,11,Disability,0 |
| HC003-0000232,0.65,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,28.3,3x_week,11.9,17.0,0.725,210746,200823,0,1,8.1,1,Weekly,0.865,0,0,0,1,11.5,High_titer,28,1,0,N/A,0,0,Emicizumab_bypass,0,2,2,0,0,0,0,0,0,4,36.2,12.7,None,55.8,8.6,1,0,6.8,1,0,39.9,135.9,97.0,0,N/A,0,69.8,63.2,3.2,117.5,417.0,0.102,11.95,8.61,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,35.5,38.6,100.0,18,4,9,Unemployed,2 |
| HC003-0000233,2.87,Male,White_non_Hispanic,Latin_America,Middle,A,Severe,0.1,Missense,0,1,Primary,Recombinant_EHL,31.1,Every_other_day,18.5,16.1,0.928,284437,158842,1,0,41.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,1,1,0,0,0,1,7,2.4,10.3,Moderate,13.2,13.6,1,0,16.6,1,0,41.4,121.2,128.3,0,N/A,0,50.4,81.1,2.53,10.9,596.7,0.454,8.53,2.68,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,14,43.8,58.5,65.1,5,6,12,Employed_full,0 |
| HC003-0000234,5.94,Male,Asian,US,Middle,A,Mild,10.45,Intron22_inversion,1,1,Secondary,Recombinant_EHL,41.7,3x_week,17.6,15.0,0.779,208309,133502,0,0,5.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,18,2.3,16.2,Mild,27.0,5.0,1,1,45.5,0,0,60.8,128.7,127.1,0,N/A,0,27.3,87.5,2.0,41.2,310.7,0.036,1.63,4.92,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,46.8,54.9,60.7,8,0,11,Employed_full,1 |
| HC003-0000235,0.8,Male,White_non_Hispanic,US,Low,B,Moderate,4.03,Missense,0,1,Primary,Recombinant_EHL,34.3,3x_week,16.0,23.9,0.59,207413,404490,0,0,19.4,0,N/A,0.0,1,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,7,10.0,12.1,None,3.7,6.0,0,0,42.4,0,0,31.0,140.0,145.0,0,N/A,0,50.1,99.0,2.38,90.4,366.6,0.661,13.02,5.65,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,37.0,54.3,66.8,16,5,22,Employed_full,2 |
| HC003-0000236,8.61,Male,White_non_Hispanic,US,Middle,A,Mild,29.01,Small_indel,0,0,None_on_demand,Plasma_derived,37.7,Biweekly_EHL,1.3,8.4,0.671,146372,103784,1,0,22.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,17,13,0,0,0,0,0,0,6,18.6,15.8,None,24.5,3.8,0,0,19.5,1,0,42.6,86.7,145.0,1,56.2,0,92.5,99.6,2.34,114.0,496.1,0.578,4.32,15.95,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Liver_failure_HCV,0,0,32.3,75.9,45.3,10,7,0,Disability,0 |
| HC003-0000237,0.12,Male,White_non_Hispanic,Other,Middle,A,Severe,0.1,Other,0,0,None_on_demand,Recombinant_SHL,23.1,3x_week,18.7,11.7,0.563,134286,253520,1,0,14.3,1,Weekly,0.881,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,16,11.5,18.5,Mild,23.5,2.0,1,0,65.2,1,0,48.5,136.5,120.3,0,N/A,0,68.0,92.4,3.29,115.6,551.8,0.209,15.38,7.97,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,40.9,55.0,72.6,0,13,3,Disability,0 |
| HC003-0000238,0.07,Male,White_non_Hispanic,Latin_America,Middle,A,Severe,0.1,Small_indel,0,0,None_on_demand,Recombinant_SHL,23.8,Weekly_EHL,9.3,15.7,0.859,278280,233775,0,1,6.0,1,Biweekly,0.806,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,7,2.8,0.3,Moderate,78.0,6.6,1,0,44.4,0,1,46.8,140.0,110.3,0,N/A,1,25.0,119.0,2.35,94.8,657.0,0.627,6.72,5.38,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,23,36.1,74.2,59.6,5,7,8,Employed_part,0 |
| HC003-0000239,3.71,Male,White_non_Hispanic,Europe,Low,A,Moderate,2.29,Missense,0,0,None_on_demand,Recombinant_EHL,26.1,Biweekly_EHL,16.3,23.1,0.711,322533,81674,0,0,8.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,32,24,1,3,0,0,0,0,11,15.1,19.0,Moderate,26.7,10.1,1,0,38.8,1,1,42.5,123.7,110.8,0,N/A,0,50.2,78.7,3.09,124.2,463.5,0.126,11.63,53.95,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,28.8,47.7,85.6,4,4,24,Employed_part,0 |
| HC003-0000240,1.29,Male,Hispanic,Latin_America,Middle,A,Severe,0.1,Small_indel,0,1,Secondary,Plasma_derived,26.9,Every_other_day,6.2,9.9,0.446,113903,118730,1,0,11.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,12,13.9,8.7,Severe,33.5,15.5,0,0,10.2,0,1,40.9,140.0,119.7,0,N/A,0,84.9,135.4,2.46,112.5,676.9,0.154,3.74,3.66,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,1,CNS_bleed,0,0,43.4,40.9,39.6,0,1,4,Employed_full,0 |
| HC003-0000241,1.21,Male,White_non_Hispanic,Europe,Middle,A,Mild,37.08,Missense,0,0,None_on_demand,Plasma_derived,19.9,Every_other_day,4.9,14.1,0.785,423354,129140,1,0,9.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,7,5,0,0,0,0,0,0,14,25.1,16.1,Mild,48.6,0.8,1,1,15.3,1,0,52.2,140.0,145.0,0,N/A,0,58.4,126.3,2.42,89.9,854.4,0.467,1.33,10.59,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.2,47.9,62.1,5,15,10,Unemployed,0 |
| HC003-0000242,3.92,Male,Asian,Europe,Middle,A,Mild,20.92,Small_indel,0,0,None_on_demand,Recombinant_EHL,38.1,Weekly_EHL,23.9,17.4,0.669,424399,238540,1,0,33.9,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,27,20,0,0,0,0,0,1,24,15.5,20.2,Moderate,58.2,7.8,0,0,16.1,0,0,44.1,108.3,132.5,0,N/A,1,76.5,124.3,2.22,116.5,699.3,0.255,7.04,14.9,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,27.8,67.7,53.2,0,6,9,Disability,0 |
| HC003-0000243,4.95,Male,Other,Europe,Middle,A,Moderate,3.36,Small_indel,0,1,Primary,Recombinant_SHL,35.1,Weekly_EHL,6.3,9.7,0.839,481573,149714,0,0,17.9,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,1,27,0.0,20.2,None,13.9,15.1,1,0,4.9,1,0,53.6,109.8,134.3,1,44.7,1,56.3,81.5,2.27,69.1,637.9,0.183,9.79,9.51,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,33.1,48.4,47.1,9,6,5,Employed_full,0 |
| HC003-0000244,1.65,Male,White_non_Hispanic,Europe,Middle,A,Mild,7.91,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,25.6,3x_week,18.9,35.1,0.575,321237,172337,0,0,11.7,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,12,9,0,0,0,0,0,0,31,19.6,13.0,Mild,0.0,0.9,0,0,30.5,0,0,46.7,125.6,139.6,0,N/A,0,69.0,96.7,2.84,120.5,711.5,0.275,2.87,3.64,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,37.9,41.7,70.7,7,1,5,Disability,0 |
| HC003-0000245,4.21,Male,White_non_Hispanic,US,Middle,A,Moderate,3.06,Missense,0,1,Primary,Plasma_derived,33.1,Weekly_EHL,12.7,12.2,0.753,393269,86784,0,0,19.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,11,34.0,13.4,Severe,7.4,15.6,0,1,12.0,0,1,49.8,102.5,107.1,0,N/A,0,65.8,120.2,2.03,61.1,391.7,0.865,3.81,3.48,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,23.2,59.4,57.6,3,8,2,Employed_full,2 |
| HC003-0000246,2.02,Male,White_non_Hispanic,Asia_Pacific,Middle,B,Severe,0.1,Missense,0,1,Primary,Recombinant_EHL,29.8,3x_week,9.5,19.4,0.794,995515,575478,0,0,26.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,42,15.3,19.1,Moderate,24.4,5.4,1,0,45.1,0,0,55.6,140.0,112.2,0,N/A,0,50.8,94.4,2.88,114.5,821.4,0.839,0.76,14.28,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,32.0,52.2,80.6,0,4,8,Employed_full,1 |
| HC003-0000247,1.0,Male,Hispanic,Asia_Pacific,Middle,A,Moderate,4.51,Intron22_inversion,1,0,None_on_demand,Plasma_derived,33.8,Weekly_EHL,11.7,11.6,0.637,223930,186390,0,0,13.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,15,11,1,2,0,0,0,0,18,26.8,0.0,Moderate,33.8,12.3,0,0,34.4,0,0,38.3,130.8,134.4,0,N/A,1,77.6,80.4,3.12,113.5,434.4,0.424,3.96,20.92,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,46.9,61.7,54.6,14,12,10,Disability,0 |
| HC003-0000248,0.49,Male,White_non_Hispanic,US,High,B,Severe,0.1,Other,0,1,Secondary,Plasma_derived,17.2,Weekly_EHL,4.2,11.5,0.783,143284,230845,0,0,28.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,1,3,8.9,4.4,None,0.0,6.7,0,1,43.7,0,0,55.3,115.9,111.0,0,N/A,0,98.7,79.3,2.1,83.0,929.3,0.227,1.65,7.79,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.6,49.3,56.5,4,8,8,Employed_part,0 |
| HC003-0000249,2.75,Male,Asian,Europe,Middle,A,Mild,25.27,Other,0,0,None_on_demand,Recombinant_SHL,26.8,Every_other_day,11.9,12.1,0.667,106891,137268,1,0,2.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,11,8,1,1,0,0,0,0,15,21.8,9.8,None,78.0,10.8,1,0,16.4,0,1,40.1,86.8,97.5,0,N/A,0,73.5,80.7,3.0,120.4,788.7,0.457,6.78,2.49,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,34,31.2,46.8,90.2,12,7,2,Employed_full,0 |
| HC003-0000250,4.28,Male,Black_non_Hispanic,US,High,B,Severe,0.1,Large_deletion,0,1,Tertiary,Recombinant_SHL,27.5,Every_other_day,5.5,13.6,0.701,769429,129792,1,0,32.1,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,8,6.1,1.3,Moderate,0.0,17.7,0,0,37.3,1,0,25.2,120.0,105.5,0,N/A,0,67.3,67.5,2.92,156.7,750.2,0.151,5.86,8.24,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,51.9,72.6,43.1,6,1,10,Employed_full,2 |
| HC003-0000251,5.34,Male,Black_non_Hispanic,Other,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,33.0,Every_other_day,9.6,12.4,0.614,775507,468056,0,0,17.9,1,Weekly,0.99,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,0,0,1,3,0,0,0,0,21,12.0,9.8,None,17.6,7.3,0,0,53.2,0,0,38.0,91.3,144.0,0,N/A,0,46.5,180.4,2.83,54.2,758.0,0.767,4.54,31.92,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,43.8,47.7,51.0,14,6,18,Employed_full,0 |
| HC003-0000252,0.6,Male,Hispanic,Asia_Pacific,Low,A,Moderate,1.49,Intron22_inversion,1,1,Primary,Plasma_derived,23.0,Biweekly_EHL,17.6,11.1,0.567,154082,68985,1,0,17.4,1,Weekly,0.871,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,13,12.1,9.4,None,5.2,14.0,1,0,25.2,1,0,33.3,130.2,118.3,0,N/A,0,85.6,45.3,2.08,133.2,649.7,0.644,12.91,3.3,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,47.6,47.6,18.7,10,5,12,Employed_full,1 |
| HC003-0000253,2.05,Male,Other,Other,Middle,A,Severe,0.1,Missense,0,1,Primary,Plasma_derived,10.0,Biweekly_EHL,13.5,13.2,0.921,173444,206762,1,0,9.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,1,7,20.7,12.7,Moderate,33.9,9.6,0,0,33.0,1,1,46.5,65.0,129.1,0,N/A,1,53.8,72.5,2.34,138.5,508.5,1.412,5.43,6.13,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,31.4,60.6,55.7,8,6,4,Disability,5 |
| HC003-0000254,1.03,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_EHL,19.3,Weekly_EHL,3.1,18.4,0.739,220931,98150,0,0,3.3,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,1,0,0,0,26,5.1,11.5,None,18.5,3.3,0,1,32.8,1,0,38.6,140.0,106.4,0,N/A,1,77.3,116.7,2.34,86.7,480.5,0.159,5.23,8.6,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,36.9,28.1,71.7,3,0,4,Unemployed,1 |
| HC003-0000255,3.42,Male,White_non_Hispanic,US,High,B,Mild,19.3,Missense,0,1,Secondary,Recombinant_SHL,27.5,Every_other_day,17.1,10.3,0.902,559363,146899,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,1,2,0.0,20.6,None,33.9,7.1,1,0,44.0,0,0,43.5,106.5,131.8,1,65.9,0,81.8,80.9,3.45,127.0,965.3,0.144,5.8,21.74,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.9,63.3,67.7,13,2,5,Employed_full,4 |
| HC003-0000256,0.44,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_EHL,28.5,3x_week,12.0,24.3,0.789,123948,130738,1,0,8.8,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,9,20.6,16.6,None,32.7,6.8,0,0,25.7,1,0,54.2,81.2,120.1,0,N/A,0,86.7,90.2,2.39,84.8,668.6,0.468,2.81,5.07,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Liver_failure_HCV,0,0,42.5,73.9,64.0,6,4,7,Disability,0 |
| HC003-0000257,0.12,Male,Other,US,Low,A,Moderate,1.46,Small_indel,0,0,None_on_demand,Recombinant_EHL,41.5,Every_other_day,8.7,18.8,0.715,82457,109865,0,0,25.1,1,Weekly,0.851,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,10,20.2,11.4,None,38.9,0.0,0,1,20.1,0,0,59.8,114.7,133.0,0,N/A,0,87.1,111.1,2.31,145.2,449.3,0.242,9.91,12.62,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,65.1,64.7,49.7,3,8,9,Employed_full,0 |
| HC003-0000258,0.72,Male,Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Tertiary,Plasma_derived,32.7,3x_week,16.5,8.7,0.787,985110,183088,0,0,6.5,0,N/A,0.0,0,0,0,1,0.8,Low_titer,26,1,0,N/A,0,0,rFVIIa,0,4,3,0,0,0,0,0,0,8,16.3,9.3,None,17.9,10.8,0,0,8.1,0,1,45.5,115.3,116.4,0,N/A,0,86.3,128.9,1.83,5.0,743.0,0.67,2.15,28.55,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.9,45.6,59.3,6,0,1,Employed_full,2 |
| HC003-0000259,0.14,Male,Black_non_Hispanic,US,Low,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_EHL,28.7,Every_other_day,11.0,21.8,0.826,323652,49811,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,1,5,0,1,0,0,10,26.2,11.6,None,0.0,11.9,0,0,16.6,0,0,55.0,113.7,134.1,0,N/A,0,37.4,92.3,1.91,152.8,711.7,0.864,6.29,2.15,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,0,0,51.9,48.8,56.4,7,12,6,Employed_full,3 |
| HC003-0000260,0.94,Male,White_non_Hispanic,Other,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,27.7,Weekly_EHL,5.0,8.0,0.873,352444,153623,0,0,7.1,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,1,8,12.6,11.8,Mild,7.8,12.9,0,0,3.3,1,0,39.9,140.0,115.5,0,N/A,1,46.1,125.8,2.06,50.5,590.7,1.176,11.88,2.51,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,1,65.2,56.6,61.9,11,11,14,Employed_full,0 |
| HC003-0000261,0.98,Male,Other,US,Middle,A,Mild,33.38,Large_deletion,1,0,None_on_demand,Recombinant_SHL,36.8,Every_other_day,23.1,11.0,0.727,237266,171932,1,0,13.4,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,49,37,0,0,0,0,0,0,8,18.4,32.2,Mild,52.3,16.6,0,1,44.8,0,0,23.2,122.6,123.6,1,67.9,1,34.8,52.5,2.58,98.6,488.4,0.316,1.97,7.5,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,58.9,59.7,64.4,0,2,5,Employed_full,2 |
| HC003-0000262,0.23,Male,White_non_Hispanic,US,Middle,B,Mild,16.91,Missense,0,0,None_on_demand,Plasma_derived,23.3,3x_week,11.9,9.1,0.835,354857,91159,1,0,13.9,0,N/A,0.0,1,1,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,45,34,0,0,0,0,0,0,39,10.8,0.3,Mild,38.6,13.7,0,0,4.7,0,0,27.8,130.9,120.1,0,N/A,1,33.3,83.0,1.69,62.4,782.4,0.609,1.53,19.73,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,15,41.7,72.1,57.1,19,16,7,Employed_part,1 |
| HC003-0000263,6.17,Male,White_non_Hispanic,Asia_Pacific,High,C,Severe,0.1,N/A,0,1,Secondary,Recombinant_EHL,26.9,Biweekly_EHL,11.5,18.6,0.633,108172,383314,1,0,16.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,1,0,0,32,11.9,4.6,Moderate,8.9,4.4,1,0,38.3,0,0,39.7,110.0,125.5,0,N/A,0,98.6,113.9,2.07,154.9,820.3,0.199,1.94,11.01,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,52.6,71.7,62.3,9,7,5,Employed_full,0 |
| HC003-0000264,0.6,Male,Other,Europe,Middle,A,Mild,35.62,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,19.3,Weekly_EHL,9.6,10.5,0.428,162016,133622,0,0,30.4,1,Weekly,0.927,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,7,5,0,0,1,0,0,0,9,19.1,3.4,Mild,46.6,5.7,1,0,56.9,0,0,51.5,123.5,130.0,0,N/A,1,43.3,155.2,1.47,85.8,708.0,0.358,19.18,21.38,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,41.4,53.8,60.6,7,6,6,Employed_full,0 |
| HC003-0000265,2.39,Male,White_non_Hispanic,Latin_America,Middle,A,Moderate,2.2,Intron22_inversion,1,1,Primary,Recombinant_SHL,39.4,Every_other_day,19.1,10.5,0.854,285813,159733,0,0,33.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,0,3,42.2,14.2,Mild,24.2,13.0,0,0,53.9,1,0,39.7,88.8,116.1,1,48.6,1,40.2,73.0,3.1,73.3,662.9,0.289,2.75,1.76,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.6,50.7,52.6,9,8,9,Employed_part,0 |
| HC003-0000266,0.4,Male,White_non_Hispanic,Europe,Middle,B,Mild,14.58,Missense,0,0,None_on_demand,Non_factor,31.1,Biweekly_EHL,8.9,15.7,0.649,68697,133772,0,0,42.1,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,15,11,1,6,0,0,0,0,7,23.9,13.8,Mild,34.8,10.3,0,1,20.1,1,0,56.2,120.2,122.8,0,N/A,0,63.8,68.0,2.45,139.8,509.2,0.277,1.72,11.14,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,6,49.3,48.2,63.1,0,8,5,Unemployed,1 |
| HC003-0000267,1.02,Male,Hispanic,Asia_Pacific,High,A,Mild,10.51,Intron22_inversion,1,1,Secondary,Recombinant_SHL,22.3,3x_week,2.7,12.3,0.91,223796,172684,0,0,1.0,0,N/A,0.0,0,1,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,1,13,21.6,7.4,Mild,23.2,7.9,0,0,10.3,0,0,64.0,99.8,128.4,0,N/A,0,48.6,109.6,2.56,124.3,736.4,1.296,6.01,0.63,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,49.7,62.4,44.1,8,6,23,Disability,0 |
| HC003-0000268,0.18,Male,White_non_Hispanic,Europe,High,A,Mild,15.73,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,27.1,3x_week,7.9,17.1,0.435,215669,345958,0,0,7.7,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,27,20,0,0,0,0,0,0,16,24.3,19.2,None,28.1,2.8,0,0,40.7,1,0,31.3,140.0,134.1,0,N/A,1,114.8,101.5,1.86,81.7,535.8,0.103,0.51,26.94,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,6,45.6,66.8,64.5,10,2,8,Disability,1 |
| HC003-0000269,0.24,Male,White_non_Hispanic,Europe,Low,A,Mild,6.22,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,32.1,Weekly_EHL,20.0,21.2,0.47,223773,619401,1,0,26.4,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,11,8,0,0,0,0,1,0,3,0.0,15.0,Severe,0.0,4.8,0,0,10.9,0,0,65.0,116.5,123.6,0,N/A,0,59.0,79.9,2.98,55.4,421.0,0.3,2.09,23.8,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,38.2,56.7,46.4,6,4,2,Employed_full,1 |
| HC003-0000270,0.02,Male,White_non_Hispanic,Latin_America,Middle,A,Moderate,2.72,Intron22_inversion,1,1,Primary,Recombinant_EHL,26.0,Weekly_EHL,17.0,14.6,0.685,192789,261142,1,0,12.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,1,4,0,0,0,0,7,18.8,19.5,Mild,32.9,11.5,0,0,12.2,0,0,22.4,128.3,109.0,0,N/A,1,74.8,65.9,3.15,50.0,852.6,0.314,13.89,6.07,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.7,56.0,61.6,10,7,10,Employed_full,0 |
| HC003-0000271,3.23,Male,White_non_Hispanic,Europe,Low,A,Moderate,2.19,Small_indel,0,1,Secondary,Recombinant_EHL,23.7,3x_week,10.5,13.6,0.536,147630,309898,0,0,28.3,1,Biweekly,0.874,1,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,15,25.9,21.6,Mild,0.0,0.0,0,1,39.1,1,1,64.2,120.2,126.6,0,N/A,0,47.8,85.6,2.43,146.0,464.6,0.504,2.09,1.02,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,26.7,77.1,68.5,11,9,6,Employed_part,0 |
| HC003-0000272,0.71,Male,Asian,US,High,A,Severe,0.1,Small_indel,0,1,Secondary,Non_factor,22.8,3x_week,20.2,22.0,0.738,89929,424308,0,0,20.5,0,N/A,0.0,0,0,0,1,6.0,High_titer,8,0,0,N/A,0,0,aPCC,0,2,2,0,0,0,0,0,0,18,16.0,0.0,Mild,21.6,0.0,0,1,37.7,0,0,41.6,140.0,137.1,0,N/A,0,28.4,114.6,2.16,111.8,308.6,0.125,3.64,6.76,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,41.8,62.8,49.0,3,12,9,Employed_full,0 |
| HC003-0000273,1.39,Male,Hispanic,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Plasma_derived,30.7,3x_week,16.5,15.1,0.624,292684,203707,0,0,37.0,1,Monthly,0.981,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,1,4,0,0,0,1,15,14.5,17.5,Moderate,28.3,12.2,0,0,63.0,1,1,39.2,83.8,101.0,0,N/A,0,49.0,90.7,2.68,101.9,885.6,0.237,5.67,22.29,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.6,35.5,76.5,13,4,5,Disability,0 |
| HC003-0000274,1.74,Male,White_non_Hispanic,US,Middle,A,Mild,14.84,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,25.1,Every_other_day,10.4,22.7,0.546,224117,394402,1,1,30.5,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,29,22,0,0,0,0,0,1,3,3.7,1.7,Mild,78.0,4.8,0,1,17.7,0,0,41.9,112.7,101.2,0,N/A,1,49.2,132.8,2.77,114.7,336.0,0.187,5.67,11.85,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,49.1,55.7,87.0,7,6,2,Disability,0 |
| HC003-0000275,0.36,Male,White_non_Hispanic,Latin_America,Low,A,Severe,0.1,Missense,0,1,Secondary,Recombinant_EHL,24.4,Weekly_EHL,11.0,16.9,0.268,117575,267320,0,1,30.7,0,N/A,0.0,0,0,0,1,0.7,Low_titer,14,0,0,N/A,0,0,aPCC,0,0,0,0,0,0,0,0,0,8,9.8,14.0,Mild,16.9,10.8,0,0,23.6,1,1,32.4,95.8,113.1,0,N/A,0,49.1,96.2,2.84,17.1,579.8,0.05,2.93,43.1,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,23.9,58.0,52.9,17,3,6,Employed_part,2 |
| HC003-0000276,5.87,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_EHL,17.3,Every_other_day,14.0,15.8,0.599,278597,193299,1,1,13.1,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,13,5.0,11.4,Mild,31.1,17.5,1,0,19.9,0,0,60.0,74.0,121.5,1,69.5,1,29.8,116.8,2.73,82.0,452.8,0.763,6.94,6.25,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,5,41.1,53.3,60.0,14,10,15,Disability,0 |
| HC003-0000277,1.09,Male,Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,28.6,3x_week,7.0,8.7,0.314,224814,214308,0,0,16.8,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,1,8,27.0,11.8,Moderate,8.1,1.9,0,0,10.1,1,0,33.7,94.5,85.5,0,N/A,0,68.0,107.8,2.88,83.1,519.7,0.093,14.25,50.73,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,26,37.8,68.6,79.0,9,5,5,Employed_full,1 |
| HC003-0000278,0.15,Female,Other,US,Low,A,Severe,0.1,Large_deletion,1,0,None_on_demand,Non_factor,26.6,3x_week,12.0,12.9,0.601,203493,72352,1,0,14.3,0,N/A,0.0,0,0,0,1,10.4,High_titer,24,1,1,High_dose,1,12,rFVIIa,0,28,21,0,0,0,0,0,0,20,33.0,2.4,None,49.9,0.0,0,1,22.3,0,1,35.2,138.4,135.3,0,N/A,1,57.6,88.7,2.05,134.3,1050.3,0.084,1.92,1.32,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.4,52.7,36.8,3,4,7,Employed_part,0 |
| HC003-0000279,0.22,Male,Other,Asia_Pacific,Low,A,Mild,28.1,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,25.4,Every_other_day,13.9,10.3,0.701,73560,208159,0,0,1.0,1,Weekly,0.893,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,25,38.2,20.2,Severe,6.5,6.3,0,0,20.2,1,0,25.4,114.4,121.7,0,N/A,1,31.1,123.3,2.86,36.2,631.7,0.643,3.04,4.12,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,53.7,46.2,62.5,6,6,4,Unemployed,1 |
| HC003-0000280,0.99,Male,White_non_Hispanic,US,High,A,Mild,9.98,Missense,0,1,Secondary,Recombinant_SHL,29.6,3x_week,1.9,8.4,0.791,404198,83127,1,0,35.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,7,4.8,1.7,Moderate,40.5,3.9,0,0,13.5,0,1,33.2,110.6,82.7,1,45.9,0,67.3,65.9,2.17,137.1,714.8,0.23,4.12,2.54,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,54.1,48.9,57.8,12,0,9,Employed_part,2 |
| HC003-0000281,0.25,Male,White_non_Hispanic,Latin_America,Middle,A,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_SHL,34.0,3x_week,10.9,11.4,0.814,128049,79807,1,1,26.9,0,N/A,0.0,0,0,0,1,17.7,High_titer,5,0,0,N/A,0,0,aPCC,0,41,31,1,3,0,0,0,0,15,7.0,18.0,None,78.0,7.8,1,0,33.7,0,0,33.6,130.5,105.0,1,52.0,1,81.8,84.5,1.15,166.8,792.3,0.237,7.85,15.82,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,23,51.2,62.7,74.6,4,8,6,Employed_full,6 |
| HC003-0000282,0.65,Male,White_non_Hispanic,Asia_Pacific,Low,B,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_SHL,33.6,3x_week,10.2,16.2,0.66,278720,198083,0,0,13.9,0,N/A,0.0,0,1,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,41,31,0,0,0,0,0,1,7,6.0,0.5,None,18.2,11.2,1,1,8.6,0,0,32.8,117.3,119.6,0,N/A,1,91.4,88.4,2.17,26.2,533.6,0.241,4.6,2.74,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,41.0,42.5,58.6,9,5,1,Employed_full,0 |
| HC003-0000283,1.49,Male,Hispanic,US,Middle,A,Severe,0.1,Missense,0,1,Primary,Recombinant_EHL,32.4,Every_other_day,18.2,15.7,0.86,165221,103049,0,1,33.7,1,Biweekly,0.939,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,1,8,2.8,11.9,Severe,17.6,10.0,1,0,17.9,0,0,39.9,127.3,93.1,0,N/A,0,25.0,110.7,2.12,95.7,843.5,0.711,4.05,20.18,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,37.9,51.1,68.3,10,17,11,Employed_full,0 |
| HC003-0000284,0.08,Male,White_non_Hispanic,Latin_America,High,B,Severe,0.1,Missense,0,1,Tertiary,Plasma_derived,26.1,Weekly_EHL,1.0,16.5,0.495,212514,179233,0,0,10.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,11,3.0,26.4,None,26.2,8.3,1,1,31.8,1,0,28.6,121.5,142.5,1,44.1,0,48.9,117.7,2.52,115.0,717.7,0.194,1.3,15.12,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,53.2,64.5,50.5,6,4,9,Employed_full,0 |
| HC003-0000285,0.72,Male,Hispanic,US,Middle,A,Mild,8.9,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,23.5,Biweekly_EHL,9.7,13.8,0.689,535725,192763,0,1,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,17,13,0,0,0,0,0,0,3,8.8,30.9,None,57.1,14.3,0,0,72.9,0,0,61.1,125.9,128.4,0,N/A,0,34.8,77.2,2.82,129.9,785.7,0.485,1.81,9.59,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,58.8,42.4,75.3,3,5,8,Employed_part,5 |
| HC003-0000286,3.14,Male,Hispanic,US,Middle,A,Moderate,4.05,Intron22_inversion,1,1,Secondary,Recombinant_EHL,19.6,3x_week,9.1,15.2,0.805,369155,197111,0,0,30.1,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,9,25.5,0.0,None,17.6,12.0,1,0,19.8,1,0,40.2,106.0,137.2,0,N/A,1,50.6,73.2,2.5,8.4,519.5,0.121,5.23,7.36,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,12,57.6,45.6,46.3,15,10,9,Employed_full,0 |
| HC003-0000287,0.15,Male,White_non_Hispanic,Latin_America,Middle,C,Moderate,1.98,N/A,0,0,None_on_demand,Recombinant_SHL,23.3,3x_week,17.8,10.0,0.669,528619,114455,1,0,2.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,14,10,1,4,0,0,0,0,8,6.4,6.4,None,78.0,6.9,1,0,5.6,0,0,46.5,135.9,106.5,0,N/A,1,95.5,102.2,3.4,108.5,729.9,0.392,2.97,3.16,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,45.4,39.0,74.2,9,9,14,Disability,3 |
| HC003-0000288,1.94,Male,White_non_Hispanic,Asia_Pacific,Middle,B,Moderate,1.34,Missense,0,0,None_on_demand,Recombinant_EHL,28.2,Every_other_day,11.7,21.6,0.772,327169,281909,0,0,15.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,13,10,0,0,0,0,0,0,9,27.6,7.8,Mild,67.1,11.8,0,0,41.6,1,0,52.3,90.8,132.4,0,N/A,1,49.0,56.9,2.14,86.3,648.4,0.62,3.41,13.99,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,26,40.4,47.0,63.1,5,10,7,Employed_part,0 |
| HC003-0000289,0.1,Male,White_non_Hispanic,US,Low,A,Mild,9.63,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,21.7,Every_other_day,22.8,12.7,0.671,340335,172023,0,1,20.5,1,Biweekly,0.781,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,2,31.4,30.0,Moderate,30.8,0.0,0,0,18.0,0,1,65.0,113.3,113.1,0,N/A,0,54.5,128.2,1.41,83.7,853.4,0.927,4.27,5.14,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,47.6,50.8,29.0,3,5,5,Employed_full,2 |
| HC003-0000290,5.36,Male,White_non_Hispanic,Europe,Middle,A,Mild,7.71,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,28.8,3x_week,16.0,21.7,0.607,92163,224255,0,0,22.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,23,17,0,0,0,0,0,1,3,18.4,11.5,Moderate,0.2,14.4,0,0,41.9,1,0,52.9,136.9,121.5,0,N/A,0,46.8,93.7,2.54,177.8,552.7,0.087,29.18,16.17,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,48.3,53.6,62.9,11,1,10,Employed_full,0 |
| HC003-0000291,0.51,Male,White_non_Hispanic,US,Low,A,Moderate,2.66,Intron22_inversion,1,1,Secondary,Non_factor,20.3,Biweekly_EHL,9.5,20.8,0.383,221790,98892,0,0,28.2,1,Weekly,0.929,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,1,4,0,0,0,0,4,29.7,20.6,None,31.9,8.1,1,0,55.3,1,0,39.0,111.9,131.4,0,N/A,0,100.8,67.3,2.13,86.4,1015.8,0.238,3.01,31.19,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,35.6,46.8,70.5,7,17,9,Employed_full,0 |
| HC003-0000292,0.49,Male,Black_non_Hispanic,Europe,Low,A,Moderate,4.09,Small_indel,0,1,Primary,Recombinant_SHL,14.7,Weekly_EHL,13.4,9.8,0.768,234463,164528,0,0,25.0,1,Biweekly,0.845,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,0,14,0.0,14.4,Mild,10.2,0.8,0,1,9.6,1,1,29.1,106.4,123.7,0,N/A,0,25.0,66.7,1.86,113.0,711.0,1.082,13.59,6.13,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,37.9,52.2,44.8,12,8,10,Employed_part,0 |
| HC003-0000293,2.18,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,34.6,3x_week,9.9,21.3,0.859,559164,311342,1,1,24.6,1,Weekly,0.827,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,7,5,0,0,0,0,0,0,15,8.3,2.4,None,29.0,5.5,1,0,21.5,0,0,46.1,140.0,139.6,0,N/A,0,52.8,108.8,2.25,90.2,627.5,0.63,12.82,26.58,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,8,70.0,65.8,50.1,2,7,7,Employed_full,2 |
| HC003-0000294,4.52,Male,White_non_Hispanic,Europe,High,C,Mild,35.61,N/A,0,0,None_on_demand,Recombinant_SHL,24.2,Biweekly_EHL,17.2,17.2,0.695,198048,292169,0,0,8.5,0,N/A,0.0,0,1,1,0,0.0,None,0,0,0,N/A,0,0,N/A,0,10,8,0,0,0,0,0,0,2,17.3,0.0,Mild,0.0,14.2,0,0,55.0,1,0,54.7,140.0,127.5,0,N/A,0,46.0,108.0,2.01,104.6,606.4,0.257,8.53,9.61,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,35.6,59.3,63.2,9,9,1,Disability,3 |
| HC003-0000295,6.38,Male,Hispanic,Europe,Middle,A,Severe,0.1,Missense,0,1,Primary,Recombinant_SHL,21.3,3x_week,4.0,10.2,0.825,314555,120735,0,0,21.5,1,Weekly,0.935,0,0,0,1,117.5,High_titer,8,0,1,Low_dose,0,11,rFVIIa,0,4,3,0,0,0,0,0,0,14,17.7,7.1,Mild,39.3,3.4,0,0,18.9,0,0,43.7,117.8,116.7,0,N/A,0,27.1,78.5,2.06,117.1,648.8,0.302,2.28,13.86,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,49.4,77.3,54.8,5,1,6,Unemployed,0 |
| HC003-0000296,2.76,Male,Black_non_Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Tertiary,Recombinant_EHL,19.2,Every_other_day,7.1,22.9,0.607,307261,136929,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,1,10,32.2,30.5,Severe,22.8,10.5,0,0,31.5,0,0,42.8,95.6,140.2,0,N/A,0,89.2,96.8,3.16,130.7,536.8,0.382,5.0,2.46,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.3,49.3,66.6,16,4,14,Employed_full,0 |
| HC003-0000297,3.46,Male,White_non_Hispanic,Latin_America,Middle,A,Mild,38.04,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,31.4,3x_week,14.7,13.5,0.835,537458,109717,0,0,36.7,1,Weekly,0.784,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,9,7,1,2,0,0,0,0,12,3.0,14.1,Moderate,0.5,13.3,0,0,30.8,0,0,44.6,74.3,144.0,0,N/A,0,25.3,68.4,2.46,63.9,770.0,0.223,3.28,4.36,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,38.6,51.5,59.1,9,2,5,Employed_part,1 |
| HC003-0000298,2.19,Male,Asian,Latin_America,Middle,A,Mild,6.63,Missense,0,0,None_on_demand,Recombinant_EHL,39.0,Every_other_day,19.4,18.5,0.758,247645,129546,1,0,1.2,0,N/A,0.0,0,0,1,0,0.0,None,0,0,0,N/A,0,0,N/A,0,30,22,0,0,0,0,0,0,12,8.6,20.4,Moderate,29.5,8.1,1,1,0.1,1,0,19.6,129.2,126.6,0,N/A,0,54.9,92.8,2.27,101.1,647.9,0.467,22.46,4.32,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,29.9,57.5,43.5,2,7,13,Disability,1 |
| HC003-0000299,0.39,Male,Other,Latin_America,Middle,A,Severe,0.1,Small_indel,0,0,None_on_demand,Recombinant_SHL,24.8,Weekly_EHL,1.0,11.6,0.745,440944,89363,1,0,13.8,0,N/A,0.0,0,0,0,1,9.4,High_titer,13,0,1,Low_dose,1,19,rFVIIa,0,24,18,0,0,0,0,0,0,14,14.0,0.7,Mild,28.2,2.8,0,1,35.7,0,0,43.8,140.0,145.0,0,N/A,0,63.3,141.3,3.2,102.5,999.9,0.446,6.22,27.19,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,29.9,50.9,94.6,12,0,18,Disability,2 |
| HC003-0000300,2.33,Male,Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,26.3,3x_week,20.2,13.7,0.548,96479,167864,0,1,2.2,0,N/A,0.0,0,0,0,1,0.5,Low_titer,14,1,0,N/A,0,0,rFVIIa,0,2,2,0,0,0,0,0,0,10,8.8,9.4,Mild,9.4,7.6,0,0,30.1,1,0,50.8,122.9,120.8,0,N/A,0,48.5,159.7,2.25,29.1,572.0,0.123,3.78,5.9,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,46.8,55.7,57.2,13,9,13,Disability,2 |
| HC003-0000301,0.33,Male,Hispanic,Europe,Middle,A,Severe,0.1,Small_indel,0,1,Secondary,Recombinant_EHL,36.6,Weekly_EHL,11.2,20.8,0.662,101884,246858,0,0,9.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,11,2.5,18.2,Mild,26.2,0.0,0,1,37.8,0,0,41.5,80.8,122.7,0,N/A,0,26.8,94.1,1.78,56.9,628.3,0.204,18.69,14.26,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,22,45.5,36.8,63.7,5,11,4,Disability,0 |
| HC003-0000302,1.98,Male,White_non_Hispanic,Europe,Middle,A,Moderate,4.4,Intron22_inversion,1,1,Primary,Plasma_derived,13.5,3x_week,1.0,11.2,0.465,68186,121476,0,0,18.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,19,9.3,3.3,Moderate,29.8,5.1,0,1,21.0,1,1,55.5,118.2,125.1,0,N/A,0,61.3,112.1,1.74,130.6,571.8,0.209,3.38,7.56,0,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,60.2,52.3,86.8,3,11,15,Employed_full,1 |
| HC003-0000303,1.53,Female,Other,US,High,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,43.7,Biweekly_EHL,1.0,11.7,0.754,430022,171905,0,0,11.7,0,N/A,0.0,1,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,9,7,0,0,0,0,0,0,12,12.1,11.5,Severe,0.0,1.4,0,0,27.6,1,0,55.9,105.3,122.7,0,N/A,0,48.2,111.0,2.36,76.5,986.4,0.246,6.97,5.87,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.3,64.8,74.1,0,8,4,Employed_part,0 |
| HC003-0000304,0.72,Male,White_non_Hispanic,US,High,A,Mild,31.6,Large_deletion,1,1,Secondary,Recombinant_SHL,47.6,3x_week,2.8,16.4,0.945,401997,161095,0,0,31.7,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,1,32.4,5.0,Severe,25.1,7.7,0,0,62.6,1,0,36.0,118.2,119.4,0,N/A,0,82.8,51.8,1.58,199.5,389.8,0.374,7.86,2.15,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,41.7,75.0,69.7,13,7,3,Unemployed,0 |
| HC003-0000305,1.42,Male,Other,Europe,Low,B,Mild,30.8,Nonsense,0,0,None_on_demand,Recombinant_EHL,10.0,3x_week,11.9,16.1,0.456,459593,304845,0,0,20.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,1,1,0,0,0,0,10,2.8,18.6,Mild,10.1,0.4,0,0,2.8,1,0,47.3,140.0,112.1,0,N/A,1,76.4,67.8,1.81,133.5,666.9,0.348,5.92,1.45,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,39.5,70.5,76.8,0,4,3,Disability,5 |
| HC003-0000306,1.8,Female,Hispanic,Latin_America,Middle,A,Moderate,3.93,Intron22_inversion,1,1,Secondary,Recombinant_SHL,27.2,Every_other_day,11.6,8.3,0.338,178721,132482,0,0,12.4,0,N/A,0.0,0,1,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,5,24.8,15.2,Moderate,9.5,8.5,0,0,50.6,0,0,42.5,130.8,107.1,0,N/A,0,107.8,35.2,2.21,113.1,706.3,0.169,4.12,5.97,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,29.3,57.3,69.7,7,8,5,Disability,0 |
| HC003-0000307,0.46,Male,White_non_Hispanic,US,Low,A,Mild,39.89,Small_indel,0,0,None_on_demand,Recombinant_SHL,22.2,Biweekly_EHL,15.8,8.4,0.806,191352,134914,1,1,16.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,8,6,0,0,0,0,0,0,21,30.3,17.5,None,62.7,14.8,0,0,16.1,1,1,17.7,126.5,127.0,0,N/A,1,67.4,112.6,2.97,155.4,447.0,0.88,8.76,6.29,0,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,2,46.5,60.8,69.7,0,6,6,Employed_part,0 |
| HC003-0000308,0.84,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,25.9,3x_week,8.7,12.4,0.255,249539,117829,0,0,32.6,0,N/A,0.0,0,0,0,1,1.4,Low_titer,5,1,0,N/A,0,0,aPCC,0,6,4,1,3,0,0,0,1,7,8.8,19.0,None,56.3,15.2,1,0,17.7,0,0,39.8,114.1,145.0,0,N/A,1,78.0,154.5,3.05,125.9,1125.8,0.302,2.71,3.67,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,10,38.1,59.3,69.9,16,0,3,Employed_full,3 |
| HC003-0000309,0.85,Male,Black_non_Hispanic,Europe,Middle,A,Severe,0.1,Small_indel,0,1,Secondary,Recombinant_SHL,24.7,Every_other_day,5.4,8.6,0.751,638080,101849,0,0,28.9,1,Weekly,0.847,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,1,7,18.1,10.2,Moderate,21.6,0.5,0,1,25.1,1,0,29.6,123.3,139.7,0,N/A,0,57.1,129.8,2.73,102.4,482.5,0.971,10.92,9.23,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,24.2,50.5,59.6,14,4,4,Employed_part,0 |
| HC003-0000310,0.22,Male,Hispanic,Latin_America,Low,A,Mild,17.18,Missense,0,0,None_on_demand,Non_factor,34.5,Weekly_EHL,9.5,12.0,0.796,741401,234355,1,0,4.3,1,Monthly,0.914,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,11,21.9,20.0,Severe,25.0,4.0,0,0,47.6,1,1,43.6,100.5,132.0,0,N/A,0,102.7,101.2,2.4,38.4,656.0,0.953,3.58,47.41,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,52.2,46.4,77.0,9,9,7,Disability,2 |
| HC003-0000311,0.58,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,1,Tertiary,Recombinant_SHL,27.1,Every_other_day,12.2,13.9,0.82,432045,168122,1,0,9.8,1,Monthly,0.865,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,34,19.9,7.3,Moderate,39.6,13.1,0,0,21.7,0,0,50.2,126.1,145.0,1,25.0,1,65.2,97.3,2.11,121.6,953.1,0.129,13.07,31.03,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,33.7,58.5,71.4,12,1,7,Employed_part,1 |
| HC003-0000312,2.05,Male,Black_non_Hispanic,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,20.7,3x_week,13.4,14.1,0.767,327293,184869,0,0,23.7,0,N/A,0.0,0,0,0,1,1.7,Low_titer,29,1,0,N/A,0,0,Emicizumab_bypass,0,3,2,1,1,0,0,0,0,9,16.0,17.0,Moderate,48.6,12.2,1,0,6.5,0,1,39.4,111.1,125.3,1,35.9,1,62.7,90.1,2.59,150.9,582.5,0.203,10.35,7.98,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,3,43.6,54.9,29.8,6,1,8,Employed_full,1 |
| HC003-0000313,2.39,Male,Asian,Europe,High,B,Severe,0.1,Missense,0,1,Primary,Recombinant_EHL,26.6,3x_week,7.3,16.7,0.764,597930,340211,0,0,22.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,9,6.9,0.0,Mild,36.1,4.3,0,1,55.7,0,0,31.2,98.6,107.2,1,44.9,0,76.9,129.7,3.29,71.3,675.9,0.216,6.95,8.23,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,44.0,64.4,73.9,3,5,12,Employed_full,0 |
| HC003-0000314,1.15,Male,White_non_Hispanic,Other,Low,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,32.1,3x_week,17.4,12.9,0.692,230152,350123,0,0,5.4,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,1,11,22.9,6.0,Moderate,26.7,5.1,1,0,39.1,1,0,44.8,131.3,118.7,0,N/A,0,50.8,106.0,2.47,22.0,587.9,0.387,4.17,13.9,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Surgical_complication,1,2,42.3,32.2,50.9,0,0,11,Unemployed,1 |
| HC003-0000315,1.2,Male,White_non_Hispanic,Europe,Low,A,Severe,0.1,Missense,0,1,Secondary,Recombinant_SHL,18.5,3x_week,8.3,12.6,0.759,212232,78975,0,0,27.0,1,Monthly,0.896,0,0,0,1,10.8,High_titer,29,0,1,High_dose,1,30,rFVIIa,0,3,2,0,0,0,0,0,1,6,10.5,30.5,Mild,11.9,8.5,0,0,33.6,0,0,65.0,70.4,123.9,0,N/A,0,54.0,101.7,2.17,52.2,640.4,0.539,10.83,9.74,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,29.0,54.3,65.4,11,9,5,Disability,0 |
| HC003-0000316,0.8,Male,White_non_Hispanic,Europe,Middle,A,Mild,14.99,Small_indel,0,1,Primary,Recombinant_SHL,14.8,Every_other_day,6.8,13.8,0.498,248348,248679,1,1,7.3,1,Weekly,0.804,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,3,15.3,16.9,Mild,19.6,0.0,0,0,15.2,0,0,15.9,104.1,115.8,0,N/A,0,76.9,69.1,2.32,165.4,844.7,0.339,7.08,13.92,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,55.4,68.1,38.6,2,9,5,Employed_full,0 |
| HC003-0000317,2.33,Male,Black_non_Hispanic,Europe,Low,B,Mild,20.86,Missense,0,0,None_on_demand,Recombinant_SHL,43.9,Every_other_day,8.7,13.8,0.675,149159,201355,0,0,33.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,23,17,0,0,0,0,0,0,12,17.1,16.9,None,25.8,11.2,1,1,7.3,0,0,44.8,127.3,136.0,0,N/A,0,81.1,116.8,2.27,98.2,574.1,0.194,0.34,10.0,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,32.0,61.8,53.8,20,10,4,Unemployed,0 |
| HC003-0000318,0.81,Male,White_non_Hispanic,Latin_America,Middle,C,Mild,34.98,N/A,0,0,None_on_demand,Recombinant_EHL,22.9,Every_other_day,18.4,23.3,0.719,241589,142801,0,0,24.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,23,17,1,2,0,0,0,0,5,25.3,5.4,Mild,0.0,14.5,0,0,45.3,1,1,35.5,139.5,141.8,0,N/A,0,78.1,95.8,2.67,153.4,172.2,1.129,2.33,8.49,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,0,0,13.0,46.2,56.9,1,7,2,Employed_full,6 |
| HC003-0000319,1.92,Male,Asian,US,High,A,Mild,30.5,Small_indel,0,0,None_on_demand,Recombinant_EHL,26.9,Every_other_day,11.2,18.9,0.787,137249,211894,0,1,4.4,1,Monthly,0.92,1,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,39,38.1,3.2,None,0.0,5.7,1,1,8.6,1,1,36.9,124.4,93.8,0,N/A,1,63.2,111.1,2.02,95.8,644.1,0.212,5.13,4.34,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,49.3,42.9,69.5,12,3,7,Employed_full,0 |
| HC003-0000320,1.28,Male,White_non_Hispanic,Europe,Low,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_EHL,24.8,Biweekly_EHL,7.8,14.5,0.799,496334,75872,0,0,11.7,1,Biweekly,0.647,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,5,6.1,9.9,Moderate,14.3,0.0,0,0,35.0,1,0,40.7,101.6,122.4,0,N/A,0,70.9,128.0,2.6,75.1,661.3,0.545,5.61,10.68,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,10,49.0,55.5,53.8,13,1,12,Employed_full,1 |
| HC003-0000321,1.2,Male,Hispanic,Europe,Low,A,Mild,21.51,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,32.4,3x_week,17.6,13.6,0.505,371838,373742,0,0,11.4,1,Weekly,0.99,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,2,15.6,11.5,Severe,16.4,16.5,0,0,27.7,0,0,37.9,114.0,72.7,0,N/A,0,86.1,54.2,2.68,180.4,685.2,0.292,7.89,1.01,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,26.9,63.9,31.7,0,8,5,Employed_part,0 |
| HC003-0000322,5.75,Male,White_non_Hispanic,Other,Middle,B,Moderate,3.23,Missense,0,0,None_on_demand,Recombinant_SHL,42.2,3x_week,24.9,12.1,0.843,632691,232692,0,0,19.9,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,8,6,0,0,0,0,0,0,20,0.0,27.3,Moderate,22.1,9.3,1,0,27.0,0,0,49.2,120.8,123.4,0,N/A,0,40.9,91.7,2.57,80.1,617.0,0.286,15.47,9.78,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.9,61.2,55.1,5,9,3,Disability,1 |
| HC003-0000323,4.29,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_SHL,32.6,3x_week,13.3,14.3,0.754,100955,116705,0,0,15.6,1,Monthly,0.854,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,10,32.8,20.2,None,11.2,12.3,1,1,17.4,0,0,39.1,140.0,123.2,0,N/A,0,65.0,87.7,1.86,85.0,494.7,0.516,7.17,1.2,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,51.9,57.2,56.7,6,2,2,Disability,1 |
| HC003-0000324,1.91,Male,Black_non_Hispanic,Europe,Middle,A,Mild,13.56,Intron22_inversion,1,1,Secondary,Recombinant_EHL,15.9,Weekly_EHL,19.4,16.1,0.632,839883,134228,1,0,4.3,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,11,15.5,12.9,Mild,23.6,0.1,0,1,34.7,1,0,16.1,133.4,145.0,0,N/A,0,25.0,85.2,2.33,113.4,605.9,1.035,0.85,9.79,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Surgical_complication,0,0,55.5,62.4,70.9,24,1,15,Employed_part,1 |
| HC003-0000325,2.39,Male,White_non_Hispanic,Other,Middle,A,Severe,0.1,Small_indel,0,1,Secondary,Non_factor,16.9,Every_other_day,18.2,17.7,0.756,104455,76759,0,1,1.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,5,11.4,12.5,Mild,25.0,0.1,1,0,19.6,0,1,57.4,133.6,145.0,0,N/A,0,81.3,68.7,2.14,83.4,967.7,0.384,5.25,3.19,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,46.7,58.6,64.1,6,6,4,Employed_part,0 |
| HC003-0000326,0.3,Male,Hispanic,Europe,High,A,Severe,0.1,Intron22_inversion,1,1,Tertiary,Recombinant_EHL,24.8,Every_other_day,8.4,18.6,0.821,130746,153740,0,0,24.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,21,15.6,18.1,Moderate,22.2,10.5,1,0,24.0,1,0,55.6,116.3,141.8,0,N/A,0,47.8,79.6,2.36,126.1,642.4,0.204,11.85,24.35,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,HIV_AIDS,0,0,49.1,62.0,51.3,1,7,9,Disability,0 |
| HC003-0000327,0.93,Male,Other,US,Low,B,Severe,0.1,Missense,0,1,Primary,Recombinant_SHL,25.9,Weekly_EHL,12.2,11.6,0.563,184888,141299,0,0,21.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,15,16.2,1.4,None,59.5,14.2,0,1,27.1,0,0,34.7,93.6,107.7,0,N/A,1,48.4,69.2,2.07,112.8,767.5,0.984,4.9,8.35,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,20,47.9,65.4,65.9,9,10,9,Disability,2 |
| HC003-0000328,2.61,Male,Other,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Tertiary,Recombinant_EHL,14.2,3x_week,4.3,14.0,0.755,588088,92730,0,0,19.3,1,Monthly,0.863,0,0,1,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,0,21,6.2,0.0,Mild,0.8,1.2,1,0,46.2,1,1,42.6,86.9,106.7,0,N/A,0,62.3,123.1,3.02,114.4,463.9,0.447,5.27,7.72,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,38.5,51.6,87.7,2,9,7,Unemployed,3 |
| HC003-0000329,2.05,Male,Asian,US,Middle,A,Severe,0.1,Large_deletion,1,0,None_on_demand,Recombinant_EHL,34.6,Weekly_EHL,10.8,16.3,0.848,307228,265230,1,0,21.2,1,Weekly,0.962,0,0,0,1,1.3,Low_titer,3,1,0,N/A,0,0,rFVIIa,0,6,4,0,0,0,0,0,1,12,29.3,17.9,Moderate,12.8,7.4,1,0,38.6,0,0,56.6,109.0,105.3,0,N/A,0,78.6,110.6,2.49,70.3,597.5,0.345,3.02,11.11,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,16,28.0,47.1,78.4,7,6,3,Employed_part,0 |
| HC003-0000330,0.47,Male,White_non_Hispanic,US,High,A,Moderate,3.9,Large_deletion,1,1,Primary,Recombinant_EHL,19.3,Weekly_EHL,8.2,18.4,0.692,231817,340578,0,0,10.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,22,22.7,12.6,None,15.5,0.0,0,0,4.9,1,0,54.4,129.0,145.0,0,N/A,0,117.6,108.6,1.59,28.5,469.9,0.685,9.58,3.54,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,37.1,63.3,35.3,5,10,15,Unemployed,1 |
| HC003-0000331,6.21,Female,Hispanic,Europe,Middle,A,Mild,30.45,Small_indel,0,0,None_on_demand,Recombinant_EHL,39.9,Weekly_EHL,9.6,18.2,0.741,166779,177428,1,0,20.2,1,Monthly,0.759,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,9,7,0,0,1,0,0,0,25,24.4,1.5,Moderate,0.0,3.8,0,0,52.8,1,0,58.3,105.0,108.6,0,N/A,0,30.8,46.0,1.74,61.7,882.9,0.39,3.38,21.16,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,0,0,52.4,50.9,96.7,10,5,13,Employed_full,0 |
| HC003-0000332,0.08,Male,Asian,Latin_America,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,42.6,Every_other_day,7.5,12.7,0.804,117529,154381,1,0,48.5,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,0,4,6.8,0.0,Moderate,0.0,6.5,0,0,38.2,1,0,46.5,126.4,118.1,0,N/A,0,46.3,154.6,3.0,65.2,370.0,2.15,7.2,14.39,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,13,52.3,36.5,78.6,4,5,13,Employed_full,1 |
| HC003-0000333,2.23,Male,White_non_Hispanic,Latin_America,Low,A,Moderate,3.73,Missense,0,0,None_on_demand,Recombinant_SHL,26.0,Every_other_day,10.3,12.5,0.505,529441,223573,0,0,32.1,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,8,6,0,0,0,0,0,0,11,6.2,19.2,Moderate,0.0,10.9,0,1,64.8,1,1,51.2,99.1,108.8,0,N/A,0,70.0,88.6,2.31,106.7,717.0,0.302,6.31,4.7,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.2,70.3,84.2,4,9,7,Disability,0 |
| HC003-0000334,0.19,Male,White_non_Hispanic,US,Low,A,Severe,0.1,Missense,0,1,Primary,Recombinant_SHL,31.5,Every_other_day,15.2,14.1,0.547,433299,178114,0,0,14.5,1,Weekly,0.822,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,14,13.6,7.8,Severe,10.9,0.0,1,0,13.4,1,1,58.9,102.2,102.4,0,N/A,0,49.0,148.8,2.21,62.4,711.3,0.756,4.68,2.97,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,36.3,58.5,40.7,12,10,7,Employed_part,1 |
| HC003-0000335,4.91,Male,Black_non_Hispanic,Europe,Low,A,Mild,34.91,Missense,0,0,None_on_demand,Recombinant_SHL,18.1,Weekly_EHL,11.3,16.2,0.644,604085,104706,0,0,11.7,1,Biweekly,0.775,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,25,24.6,15.2,Moderate,31.0,15.9,0,0,7.0,0,0,37.9,140.0,131.0,0,N/A,0,83.4,121.0,2.96,36.4,699.7,0.429,6.6,5.28,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,59.1,58.1,56.2,8,10,15,Employed_part,2 |
| HC003-0000336,0.17,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_EHL,33.0,Biweekly_EHL,1.0,21.2,0.603,340473,129788,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,1,5,21.0,9.9,Mild,11.0,7.0,0,0,18.0,1,0,47.3,130.3,127.8,0,N/A,0,61.3,93.5,2.32,49.1,227.9,0.428,5.27,6.71,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,41.4,54.2,70.2,7,5,11,Employed_full,0 |
| HC003-0000337,3.1,Male,Hispanic,Other,Middle,A,Severe,0.1,Small_indel,0,1,Secondary,Recombinant_SHL,24.0,Biweekly_EHL,7.5,18.0,0.825,54981,155093,1,0,30.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,17,5.7,11.7,Mild,5.0,15.8,0,0,33.0,0,0,16.2,108.9,85.0,0,N/A,0,84.5,157.2,1.8,110.5,285.9,0.225,12.45,2.78,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,47.0,64.4,46.3,0,6,9,Employed_part,0 |
| HC003-0000338,0.36,Male,Other,US,Middle,A,Moderate,1.94,Small_indel,0,0,None_on_demand,Recombinant_SHL,19.3,Every_other_day,2.9,12.7,0.817,127166,203637,0,0,27.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,39,29,0,0,0,0,0,0,18,23.0,7.3,None,30.2,12.2,0,1,6.8,1,0,23.0,98.4,101.6,0,N/A,0,59.5,115.9,1.84,122.5,671.1,0.226,7.7,4.9,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,26.7,43.2,69.4,10,3,9,Employed_full,5 |
| HC003-0000339,9.08,Male,Hispanic,Europe,Low,A,Mild,19.0,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,25.7,Weekly_EHL,13.5,8.1,0.424,354663,180714,1,0,11.5,1,Weekly,0.796,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,19,3.3,11.4,None,50.5,13.1,0,0,14.3,1,0,48.0,134.0,129.6,0,N/A,0,77.0,93.6,2.71,74.7,483.8,0.448,10.3,4.34,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.4,56.0,84.9,5,10,15,Employed_full,2 |
| HC003-0000340,1.16,Male,White_non_Hispanic,US,High,A,Mild,28.4,Intron22_inversion,1,1,Primary,Recombinant_EHL,24.3,3x_week,15.0,14.7,0.582,214952,199822,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,15,7.1,16.6,Mild,8.4,20.1,0,0,34.1,0,0,49.8,132.5,123.7,0,N/A,0,43.9,89.0,3.41,79.0,534.3,0.15,2.43,6.16,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,51.9,58.8,57.3,8,4,2,Disability,10 |
| HC003-0000341,2.35,Male,White_non_Hispanic,Europe,High,A,Moderate,3.2,Small_indel,0,1,Primary,Recombinant_SHL,25.4,Weekly_EHL,13.5,10.9,0.831,191893,83917,0,0,4.1,1,Weekly,0.793,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,8,16.9,9.8,None,24.1,3.3,0,1,1.4,0,1,37.4,127.8,117.8,1,41.9,0,107.6,128.9,2.82,119.6,573.6,0.19,2.31,6.2,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,24.9,61.5,85.8,0,0,6,Disability,0 |
| HC003-0000342,1.96,Male,White_non_Hispanic,Europe,Low,A,Mild,19.01,Intron22_inversion,1,0,None_on_demand,Plasma_derived,35.6,3x_week,7.3,13.8,0.469,138422,250850,0,0,23.3,1,Monthly,0.884,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,21,0.9,9.3,None,49.8,8.8,1,0,21.0,1,0,34.7,111.4,135.9,1,43.4,0,27.6,85.0,2.21,101.6,460.5,0.305,4.71,11.46,0,1,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,39.6,38.9,71.8,8,4,8,Disability,1 |
| HC003-0000343,1.34,Male,White_non_Hispanic,Latin_America,Low,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_EHL,21.7,Every_other_day,13.5,21.4,0.782,473806,180179,0,0,16.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,9,3.4,16.9,Moderate,0.0,2.1,0,1,34.1,0,1,37.7,93.1,99.0,0,N/A,0,49.4,89.4,2.29,142.4,429.4,0.812,8.16,7.6,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,44.5,61.9,36.0,8,3,3,Employed_full,3 |
| HC003-0000344,2.88,Male,Black_non_Hispanic,US,Low,A,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_SHL,41.9,Every_other_day,9.2,11.1,0.605,352821,644580,0,0,26.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,25,19,0,0,0,0,0,0,11,33.6,17.4,None,24.0,7.4,1,0,25.2,0,0,44.3,114.7,114.3,0,N/A,0,33.8,83.3,2.42,88.7,650.0,0.321,6.86,10.61,1,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,4,55.7,51.8,49.8,6,0,6,Employed_part,0 |
| HC003-0000345,1.48,Male,Asian,Asia_Pacific,High,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,17.4,Biweekly_EHL,5.2,11.5,0.655,362476,148180,0,0,19.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,5,31.4,2.9,None,17.7,12.3,0,0,15.3,1,0,14.2,140.0,134.3,0,N/A,0,82.6,78.8,1.39,61.7,306.9,0.317,2.46,9.24,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,50.7,49.5,77.5,3,4,3,Employed_full,2 |
| HC003-0000346,5.48,Male,White_non_Hispanic,Europe,Low,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_SHL,40.9,3x_week,16.5,10.7,0.474,183476,211447,0,0,29.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,17,42.5,11.8,Moderate,10.3,14.8,0,1,36.0,1,1,47.6,96.8,113.3,0,N/A,0,76.9,80.6,2.41,138.5,559.0,0.129,8.37,6.2,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,58.6,40.4,47.5,13,9,8,Employed_full,1 |
| HC003-0000347,0.12,Male,White_non_Hispanic,Latin_America,Middle,A,Severe,0.1,Large_deletion,1,1,Secondary,Recombinant_SHL,19.9,3x_week,16.9,14.4,0.595,298275,740151,0,1,22.4,1,Biweekly,0.856,0,0,0,1,85.5,High_titer,9,1,0,N/A,0,0,rFVIIa,0,1,1,0,0,0,0,0,0,12,20.4,7.8,None,10.1,5.7,0,0,3.2,1,0,42.4,115.9,130.6,1,37.1,0,38.2,149.6,2.69,82.5,529.9,1.169,2.71,13.67,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,49.2,78.3,77.1,3,8,11,Employed_full,0 |
| HC003-0000348,10.72,Male,Asian,Asia_Pacific,Middle,A,Moderate,4.08,Small_indel,0,1,Primary,Recombinant_EHL,28.0,3x_week,17.7,16.5,0.481,120252,198203,1,0,27.9,0,N/A,0.0,0,0,0,1,15.1,High_titer,34,0,1,High_dose,1,73,aPCC,0,0,0,0,0,0,0,0,0,9,22.7,12.1,Mild,8.8,0.8,0,0,63.6,0,0,45.0,140.0,104.4,0,N/A,0,86.9,128.2,3.29,63.4,645.7,0.73,7.68,0.63,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,49.8,54.7,70.6,12,8,5,Employed_part,0 |
| HC003-0000349,1.66,Male,White_non_Hispanic,Other,Middle,B,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_EHL,24.1,3x_week,8.3,19.7,0.789,248228,173891,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,34,26,0,0,1,0,0,0,2,13.1,23.5,None,17.8,8.4,0,0,14.8,1,0,40.5,108.9,110.2,0,N/A,0,49.6,106.6,2.95,130.7,1079.7,0.799,5.64,5.35,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,29.5,58.5,66.4,12,12,5,Employed_full,1 |
| HC003-0000350,0.59,Male,Hispanic,US,Middle,A,Moderate,2.27,Intron22_inversion,1,1,Secondary,Plasma_derived,25.3,Biweekly_EHL,19.1,11.0,0.945,58879,109814,0,0,3.2,0,N/A,0.0,1,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,17,10.8,14.9,Moderate,3.6,2.9,0,0,5.1,1,0,25.4,112.5,92.9,0,N/A,0,73.5,84.7,3.36,153.0,473.2,0.094,3.74,4.42,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,29.2,45.5,53.9,3,4,6,Employed_full,0 |
| HC003-0000351,1.17,Male,White_non_Hispanic,US,Middle,A,Moderate,3.62,Missense,0,1,Primary,Non_factor,34.4,Every_other_day,9.0,14.9,0.622,104729,386209,0,1,13.6,1,Weekly,0.873,0,1,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,16,25.5,29.3,Mild,26.3,4.5,0,0,35.8,0,0,28.8,88.0,88.0,0,N/A,0,78.7,84.6,3.24,102.3,723.1,0.399,2.92,8.23,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,58.5,40.7,66.2,11,1,8,Employed_full,0 |
| HC003-0000352,2.49,Male,Black_non_Hispanic,US,High,A,Mild,21.75,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,40.0,Every_other_day,15.9,19.2,0.553,221154,100755,0,0,31.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,19,14,0,0,0,0,0,0,35,31.3,13.8,Mild,36.5,12.0,0,1,54.9,0,0,60.3,127.5,116.4,0,N/A,0,59.6,89.7,3.1,54.8,689.7,0.142,4.99,4.17,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,35.0,64.1,85.6,5,8,11,Employed_full,0 |
| HC003-0000353,1.99,Male,White_non_Hispanic,US,Low,A,Mild,23.37,Missense,0,0,None_on_demand,Recombinant_SHL,37.5,Weekly_EHL,8.9,8.0,0.438,1115787,222695,0,0,40.6,1,Monthly,0.99,1,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,17,24.4,10.7,None,42.1,10.9,0,0,43.5,1,1,34.3,100.2,133.1,0,N/A,1,85.0,150.1,2.41,156.4,750.8,0.558,4.79,12.11,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,34.0,42.5,56.5,10,7,13,Disability,0 |
| HC003-0000354,4.18,Male,Hispanic,Europe,High,A,Severe,0.1,Missense,0,1,Primary,Recombinant_SHL,24.8,3x_week,10.7,8.4,0.57,91086,141949,1,0,16.0,0,N/A,0.0,0,0,0,1,3.8,Low_titer,20,0,0,N/A,0,0,rFVIIa,0,7,5,0,0,0,0,0,0,12,4.9,11.8,Moderate,49.9,13.0,0,0,18.3,1,0,51.7,83.9,122.9,0,N/A,1,61.8,108.1,2.57,110.1,611.6,0.39,1.94,14.19,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,14.6,69.0,70.5,2,1,0,Employed_full,2 |
| HC003-0000355,4.55,Male,White_non_Hispanic,Other,Low,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,29.5,Every_other_day,1.0,12.0,0.504,127243,163625,1,0,10.7,1,Monthly,0.937,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,11,19.7,13.1,None,54.3,6.0,0,1,60.2,0,0,29.0,95.9,145.0,1,47.6,1,72.5,120.9,1.56,103.8,909.5,0.456,7.25,2.13,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,51.7,74.0,90.1,6,5,10,Employed_part,2 |
| HC003-0000356,1.89,Male,Hispanic,Other,Middle,A,Moderate,2.93,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,21.7,Every_other_day,10.2,15.7,0.672,305610,88259,0,0,1.0,0,N/A,0.0,0,1,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,31,23,0,0,0,0,0,0,21,5.8,14.6,Mild,0.0,14.1,1,0,22.9,0,0,41.8,119.2,117.9,0,N/A,0,59.0,105.6,2.47,78.8,773.4,0.17,11.31,9.04,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,27.7,48.2,65.7,7,8,5,Employed_full,0 |
| HC003-0000357,3.15,Male,White_non_Hispanic,Europe,High,A,Moderate,3.01,Intron22_inversion,1,1,Primary,Recombinant_SHL,20.1,Every_other_day,12.5,10.2,0.53,775803,352062,0,0,28.4,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,18,11.1,4.1,None,45.1,8.1,0,1,59.4,1,0,36.7,83.4,86.8,0,N/A,1,25.0,75.2,2.68,140.2,776.2,0.131,8.92,2.33,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,31.0,51.4,55.1,7,7,3,Employed_full,0 |
| HC003-0000358,1.34,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,18.8,Every_other_day,9.5,10.6,0.869,302944,156545,0,0,11.4,0,N/A,0.0,0,0,0,1,46.9,High_titer,13,1,1,Low_dose,1,33,aPCC,0,0,0,0,0,0,0,0,0,8,34.6,10.1,None,8.7,6.3,1,0,17.4,1,1,38.6,87.3,131.2,0,N/A,0,62.3,102.9,2.26,50.7,395.4,0.18,5.77,11.38,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,7,52.0,30.6,55.0,9,9,3,Employed_full,0 |
| HC003-0000359,0.23,Male,Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_EHL,24.5,Every_other_day,22.5,14.5,0.739,408924,97974,0,0,53.5,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,9,0.6,6.2,None,0.0,1.4,0,0,66.1,0,1,37.9,126.2,105.6,0,N/A,0,45.8,69.9,1.63,46.9,667.3,0.385,3.13,4.86,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,15.7,38.6,32.8,3,3,7,Disability,0 |
| HC003-0000360,1.09,Male,White_non_Hispanic,Other,Middle,A,Mild,32.15,Other,0,0,None_on_demand,Recombinant_EHL,30.0,Every_other_day,5.0,19.3,0.494,219134,336497,0,0,9.1,1,Monthly,0.824,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,4,41.0,20.2,None,27.4,0.0,0,0,36.8,0,0,59.3,113.6,127.3,0,N/A,0,95.6,133.5,3.19,170.8,558.2,0.248,4.97,3.58,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,54.9,62.3,45.0,4,0,5,Disability,2 |
| HC003-0000361,0.59,Male,White_non_Hispanic,US,Middle,A,Mild,39.21,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,12.7,Weekly_EHL,8.6,15.3,0.828,197526,139795,0,0,43.3,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,36,27,0,0,0,0,0,0,11,21.6,0.0,None,52.3,0.0,0,0,73.8,1,0,65.0,96.7,83.9,0,N/A,0,35.0,79.0,2.6,60.5,494.9,0.369,4.03,1.59,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,30.9,68.5,66.7,11,2,20,Disability,0 |
| HC003-0000362,3.94,Male,White_non_Hispanic,Europe,Middle,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_EHL,27.6,Weekly_EHL,6.6,24.1,0.639,281901,212629,1,1,27.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,23,9.4,13.3,None,3.1,9.3,1,0,25.4,0,0,44.9,108.6,120.0,0,N/A,0,92.0,84.0,3.26,133.4,537.2,0.133,4.95,6.8,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,5,38.4,48.2,75.6,5,9,3,Employed_full,3 |
| HC003-0000363,0.46,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Missense,0,1,Primary,Recombinant_SHL,40.1,Weekly_EHL,8.6,8.0,0.774,180778,273952,1,1,5.7,1,Monthly,0.955,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,9,15.8,0.0,Moderate,5.9,2.6,1,0,28.9,0,0,37.0,140.0,137.6,0,N/A,0,61.1,122.8,2.77,150.1,639.9,0.3,9.48,2.61,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,31.5,49.7,56.0,5,10,11,Employed_part,0 |
| HC003-0000364,2.55,Male,White_non_Hispanic,US,Middle,A,Mild,20.55,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,37.0,3x_week,18.2,18.4,0.551,414389,227981,0,1,20.8,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,17,13,0,0,0,0,0,0,9,6.8,15.5,Mild,10.6,0.0,0,1,19.1,0,0,26.0,140.0,135.4,0,N/A,0,73.9,80.4,3.08,103.4,732.2,0.92,4.11,1.94,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,25.4,40.2,75.4,3,5,13,Disability,2 |
| HC003-0000365,4.55,Male,Other,Europe,Middle,A,Severe,0.1,Other,0,1,Primary,Recombinant_SHL,23.3,3x_week,20.9,15.5,0.638,102359,59975,1,1,27.3,0,N/A,0.0,0,1,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,0,7,8.4,8.8,Mild,9.5,5.5,0,1,21.3,1,0,25.2,112.9,120.5,0,N/A,0,34.6,93.9,2.98,59.8,826.7,0.393,1.03,8.74,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,15,31.7,44.7,74.5,5,12,10,Employed_full,0 |
| HC003-0000366,0.27,Male,White_non_Hispanic,Other,Middle,A,Mild,16.98,Intron22_inversion,1,0,None_on_demand,Plasma_derived,16.8,Biweekly_EHL,7.8,12.3,0.849,457711,254658,0,0,15.3,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,39,29,0,0,0,0,0,0,11,15.9,0.0,None,40.7,9.7,1,0,2.6,1,1,59.4,131.3,124.1,0,N/A,0,58.2,30.0,2.06,120.2,818.2,0.413,8.5,17.68,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,30.9,69.3,51.2,2,5,6,Employed_full,1 |
| HC003-0000367,1.9,Male,Black_non_Hispanic,Other,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Non_factor,31.7,Weekly_EHL,7.7,13.8,0.734,274742,171047,0,0,28.1,0,N/A,0.0,0,0,0,1,53.3,High_titer,21,1,1,Low_dose,0,9,rFVIIa,0,2,2,0,0,0,0,0,1,8,11.1,19.5,None,46.0,10.5,1,0,8.8,0,0,24.4,117.4,116.1,0,N/A,0,50.4,91.0,2.15,150.7,702.7,0.416,6.16,10.54,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,12,26.5,59.1,53.7,11,4,11,Employed_full,1 |
| HC003-0000368,5.22,Male,Other,Asia_Pacific,Middle,A,Moderate,1.36,Small_indel,0,1,Primary,Recombinant_SHL,10.0,3x_week,5.1,15.7,0.454,235901,152586,0,0,27.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,7,3.8,0.0,Severe,52.8,7.8,0,0,16.0,1,0,36.7,79.5,119.6,0,N/A,1,111.3,116.6,2.19,108.7,660.0,0.2,5.05,2.04,1,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Liver_failure_HCV,0,0,57.0,38.0,43.2,5,0,1,Disability,1 |
| HC003-0000369,1.03,Male,White_non_Hispanic,Latin_America,Low,A,Severe,0.1,Intron22_inversion,1,1,Primary,Plasma_derived,36.9,Every_other_day,19.8,10.2,0.689,100128,170325,1,0,25.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,1,1,12.3,11.7,None,12.6,7.6,0,0,18.9,1,0,43.9,75.9,136.3,0,N/A,0,49.8,82.5,1.92,65.1,591.6,1.111,1.75,6.53,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,29.3,61.7,72.4,2,6,8,Employed_full,1 |
| HC003-0000370,0.98,Male,Hispanic,US,High,A,Severe,0.1,Missense,0,1,Secondary,Recombinant_EHL,26.3,3x_week,18.7,14.6,0.651,149063,80417,0,0,17.8,0,N/A,0.0,0,1,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,5,0.0,17.5,Moderate,8.6,4.8,0,0,32.6,0,0,10.8,96.8,111.5,0,N/A,0,90.4,115.7,3.28,107.2,605.4,0.401,2.3,13.63,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,19.2,79.7,62.1,6,10,14,Employed_full,1 |
| HC003-0000371,1.33,Male,Asian,US,Middle,A,Mild,18.08,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,42.7,3x_week,11.4,16.2,0.868,550835,198013,0,0,3.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,32,24,0,0,0,0,0,0,10,0.0,23.0,Moderate,21.6,11.8,0,0,24.2,0,0,27.0,83.5,113.3,0,N/A,0,90.7,99.5,2.42,39.6,509.5,0.347,2.53,6.54,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,17.3,52.1,74.4,0,11,7,Employed_part,1 |
| HC003-0000372,0.41,Male,Hispanic,Europe,Low,A,Moderate,3.66,Small_indel,0,1,Secondary,Plasma_derived,14.2,3x_week,3.6,12.2,0.71,236769,90926,0,0,17.1,1,Monthly,0.893,0,0,0,1,8.0,High_titer,22,0,1,Malmö,1,5,aPCC,0,7,5,0,0,0,0,0,0,50,0.0,0.0,Mild,7.9,6.9,0,0,3.9,1,1,25.9,120.4,96.6,0,N/A,0,90.1,130.5,2.63,56.1,572.9,0.522,2.81,9.9,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,44.8,49.3,61.2,3,10,5,Employed_full,0 |
| HC003-0000373,0.36,Male,White_non_Hispanic,Europe,Middle,A,Mild,9.69,Small_indel,0,0,None_on_demand,Recombinant_EHL,35.3,Every_other_day,4.2,14.0,0.808,317121,155917,0,0,20.1,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,39,29,0,0,0,0,0,0,11,35.1,7.9,Moderate,29.7,7.5,0,1,14.2,1,0,34.0,104.0,136.6,0,N/A,0,51.9,79.4,1.73,84.7,713.7,0.639,3.03,4.99,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,20.9,61.8,48.8,14,8,14,Employed_full,3 |
| HC003-0000374,6.21,Male,White_non_Hispanic,Europe,High,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_EHL,27.2,Biweekly_EHL,13.0,16.5,0.6,158305,194489,0,0,1.0,0,N/A,0.0,0,0,0,1,9.6,High_titer,19,0,1,Modified,0,128,aPCC,0,2,2,0,0,0,0,0,1,11,19.9,20.7,Moderate,12.6,14.2,1,0,7.4,0,1,45.1,123.5,119.2,0,N/A,0,104.7,93.2,2.81,97.5,927.3,0.111,1.74,5.23,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,38.0,66.1,72.9,2,12,8,Employed_full,2 |
| HC003-0000375,4.8,Male,White_non_Hispanic,Europe,Low,A,Mild,15.39,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,25.4,3x_week,15.3,15.4,0.746,263700,307742,0,0,20.0,1,Biweekly,0.983,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,4,22.2,21.2,Moderate,41.5,12.8,0,1,24.0,0,0,54.3,123.8,102.3,0,N/A,1,109.3,58.8,2.2,46.9,623.0,0.315,25.06,4.08,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Other,0,0,61.7,64.2,34.3,6,2,10,Unemployed,5 |
| HC003-0000376,1.18,Male,Hispanic,Europe,Low,A,Mild,8.03,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,17.0,3x_week,1.0,11.0,0.355,117796,119395,0,0,16.8,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,12,15.1,22.2,Mild,46.4,6.9,0,0,8.0,1,0,34.0,128.8,139.8,1,43.7,1,73.1,97.4,3.03,105.0,504.6,1.801,14.9,12.82,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.0,52.8,57.3,18,11,2,Employed_full,2 |
| HC003-0000377,0.65,Male,Other,Latin_America,Low,A,Moderate,4.46,Intron22_inversion,1,1,Secondary,Recombinant_SHL,32.8,Every_other_day,10.1,14.9,0.697,284910,371682,0,0,2.4,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,14,21.1,32.5,None,12.2,6.0,1,0,5.7,1,1,36.5,96.4,123.2,0,N/A,0,54.8,88.2,2.06,115.9,824.5,1.132,5.59,13.57,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,43.6,51.8,51.2,8,7,4,Employed_part,2 |
| HC003-0000378,2.69,Male,Other,US,Low,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_EHL,33.4,Weekly_EHL,21.7,17.3,0.765,335167,288782,1,0,14.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,14,29.1,7.9,Mild,37.4,6.0,0,0,10.5,1,0,40.6,125.3,110.7,0,N/A,1,46.1,126.9,3.07,86.4,289.6,0.277,4.36,4.48,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,11,34.2,38.8,83.4,4,7,10,Employed_full,1 |
| HC003-0000379,8.7,Male,White_non_Hispanic,US,Middle,A,Mild,19.98,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,42.3,Weekly_EHL,10.7,15.9,0.94,325256,145117,1,0,14.3,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,46,34,0,0,1,0,0,0,15,19.9,15.0,None,52.3,0.0,1,0,39.3,0,1,32.3,95.9,140.1,0,N/A,1,75.4,82.5,2.87,8.7,837.8,0.539,19.32,14.58,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.9,43.7,86.5,0,0,9,Employed_part,0 |
| HC003-0000380,4.33,Male,Black_non_Hispanic,US,High,A,Moderate,1.57,Missense,0,0,None_on_demand,Recombinant_SHL,36.1,Every_other_day,20.9,10.0,0.806,156037,103324,0,0,41.2,1,Weekly,0.878,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,13,34.7,9.2,None,65.6,14.6,0,0,48.0,0,0,47.0,129.2,117.9,0,N/A,1,66.4,88.1,2.17,99.2,392.1,0.232,16.43,2.05,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,HIV_AIDS,0,0,37.6,59.6,67.9,8,7,9,Unemployed,0 |
| HC003-0000381,0.97,Male,White_non_Hispanic,US,Low,B,Mild,10.86,Missense,0,0,None_on_demand,Plasma_derived,23.2,3x_week,15.9,13.0,0.431,218550,87386,0,0,20.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,26,20,0,0,0,0,0,0,11,14.6,0.0,Mild,55.4,3.9,0,0,27.3,0,0,47.4,139.5,95.8,0,N/A,1,69.0,81.1,3.11,167.6,768.3,0.4,2.48,6.33,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,43.4,50.7,53.9,3,11,12,Employed_part,0 |
| HC003-0000382,1.32,Male,Asian,Asia_Pacific,Middle,A,Severe,0.1,Large_deletion,1,1,Primary,Recombinant_SHL,20.0,Weekly_EHL,5.5,8.4,0.886,370392,206051,0,0,30.4,0,N/A,0.0,0,0,0,1,122.1,High_titer,21,1,0,N/A,0,0,aPCC,0,1,1,0,0,0,0,0,1,4,22.2,11.3,None,20.9,13.1,0,0,58.8,0,1,10.0,129.5,141.3,0,N/A,0,35.3,100.8,2.97,113.3,564.3,0.209,5.46,2.19,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,58.2,58.5,86.1,10,0,8,Employed_part,2 |
| HC003-0000383,2.19,Male,White_non_Hispanic,Europe,Low,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_SHL,17.1,Weekly_EHL,10.2,14.0,0.666,236366,124412,0,0,16.6,0,N/A,0.0,0,1,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,17,23.4,0.0,Moderate,18.8,8.2,1,0,10.0,1,0,49.7,111.5,108.9,0,N/A,0,65.7,155.7,2.64,95.6,707.8,0.206,3.87,2.67,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,9,35.3,53.6,52.2,4,9,12,Employed_full,0 |
| HC003-0000384,1.5,Male,Other,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_EHL,39.8,Every_other_day,11.2,18.6,0.917,225848,327643,0,0,1.0,1,Monthly,0.958,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,25,3.8,7.8,Severe,24.4,16.4,0,0,60.7,1,0,43.5,126.3,145.0,0,N/A,0,90.2,30.0,1.9,80.1,1025.0,0.188,3.61,2.16,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,9,31.3,56.6,42.6,8,0,5,Disability,1 |
| HC003-0000385,0.65,Male,Asian,Latin_America,Middle,C,Mild,17.12,N/A,0,0,None_on_demand,Non_factor,21.8,Weekly_EHL,6.3,20.0,0.868,840776,128058,1,1,26.1,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,50,38,0,0,0,0,0,0,10,15.5,0.3,None,19.6,11.2,0,0,12.0,1,0,45.1,84.3,116.0,0,N/A,0,82.9,98.7,2.8,118.1,499.2,1.157,3.93,4.1,1,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.2,56.2,34.2,14,0,3,Employed_part,3 |
| HC003-0000386,0.64,Male,White_non_Hispanic,Europe,Middle,A,Mild,32.78,Intron22_inversion,1,1,Primary,Recombinant_SHL,39.8,3x_week,6.2,11.6,0.526,151662,114653,0,0,10.1,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,7,0.0,15.5,None,33.6,13.5,0,0,13.7,1,0,56.2,79.8,87.7,0,N/A,0,55.9,132.9,2.43,103.3,469.9,0.205,4.18,12.91,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,50.6,63.5,63.4,10,6,1,Employed_full,0 |
| HC003-0000387,2.17,Male,White_non_Hispanic,US,Low,A,Severe,0.1,Large_deletion,1,1,Secondary,Recombinant_EHL,32.2,Every_other_day,21.0,18.3,0.653,513113,202160,1,1,14.0,1,Weekly,0.91,0,0,0,1,8.2,High_titer,24,1,0,N/A,0,0,aPCC,0,2,2,0,0,0,0,0,0,17,13.4,5.8,Mild,14.2,4.4,0,0,25.9,1,0,20.6,124.3,145.0,0,N/A,1,62.6,85.6,2.42,123.3,664.1,0.751,5.3,6.89,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,31,36.3,64.5,38.0,0,12,19,Employed_part,1 |
| HC003-0000388,6.99,Male,Asian,US,Middle,C,Mild,13.61,N/A,0,0,None_on_demand,Recombinant_SHL,30.6,Every_other_day,6.1,9.4,0.7,134214,127641,0,0,5.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,24,18,0,0,0,0,0,0,2,11.7,0.0,None,51.1,0.3,0,0,25.9,1,0,26.9,140.0,123.0,0,N/A,0,32.7,114.8,2.44,51.1,924.6,0.213,5.33,4.37,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.9,55.8,81.9,7,5,3,Employed_full,0 |
| HC003-0000389,0.38,Male,White_non_Hispanic,US,High,A,Mild,26.42,Intron22_inversion,1,1,Primary,Plasma_derived,25.5,Every_other_day,18.5,14.4,0.891,397468,180642,0,0,18.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,0,5,10.9,18.9,None,0.0,8.9,0,0,8.7,0,0,41.2,90.4,128.6,0,N/A,0,50.4,133.0,2.38,99.9,682.2,0.195,14.16,6.32,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,45.6,54.0,53.9,12,8,9,Unemployed,1 |
| HC003-0000390,2.38,Male,Hispanic,Latin_America,Middle,B,Severe,0.1,Splice_site,0,1,Secondary,Recombinant_EHL,33.3,Every_other_day,9.4,19.9,0.745,410402,294488,0,0,30.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,13,10.1,7.2,Severe,0.0,0.0,0,0,17.8,0,0,14.1,115.3,130.9,0,N/A,0,57.5,92.3,1.97,76.6,658.0,0.411,2.35,1.16,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,63.7,55.6,44.0,0,2,5,Employed_full,0 |
| HC003-0000391,5.25,Male,Asian,US,Low,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,27.9,3x_week,11.8,10.3,0.567,197557,190730,0,0,29.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,4,21.1,8.5,None,20.6,5.2,1,0,33.3,0,0,39.5,123.8,99.5,0,N/A,0,78.9,81.7,1.64,109.9,680.4,0.107,9.71,12.36,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,16,50.1,48.2,77.6,15,5,6,Employed_part,1 |
| HC003-0000392,0.03,Male,Hispanic,US,Low,A,Mild,36.54,Large_deletion,1,0,None_on_demand,Recombinant_EHL,25.0,Weekly_EHL,15.4,19.8,0.514,129251,191087,0,1,37.0,0,N/A,0.0,0,1,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,17,13,0,0,0,0,0,0,4,4.4,4.2,None,36.7,0.9,1,1,61.1,0,0,52.2,102.7,85.0,0,N/A,0,49.5,126.2,1.54,17.2,469.2,0.513,1.9,0.98,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,1,CNS_bleed,0,0,30.4,66.9,74.3,8,6,11,Disability,1 |
| HC003-0000393,1.1,Male,White_non_Hispanic,US,Middle,A,Mild,24.84,Large_deletion,1,0,None_on_demand,Recombinant_SHL,33.6,Every_other_day,8.4,13.3,0.897,82268,199301,0,0,38.7,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,25,19,0,0,0,0,0,0,13,37.3,21.2,Mild,46.5,3.0,0,0,44.3,0,0,46.8,108.2,145.0,0,N/A,0,42.2,113.9,2.55,79.3,682.3,0.27,5.42,3.91,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,15.9,50.4,85.3,10,13,19,Employed_part,0 |
| HC003-0000394,2.7,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Other,0,1,Secondary,Recombinant_SHL,26.8,Biweekly_EHL,15.4,12.0,0.376,185523,77146,1,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,23,21.8,14.2,None,23.2,11.6,0,0,19.9,1,0,42.9,127.3,95.9,0,N/A,0,81.7,98.3,1.19,116.7,579.3,0.194,10.33,6.88,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,41.7,54.4,38.2,5,3,6,Employed_full,0 |
| HC003-0000395,4.55,Male,White_non_Hispanic,US,Middle,B,Mild,11.78,Large_deletion,0,0,None_on_demand,Recombinant_SHL,21.6,Every_other_day,1.0,8.0,0.773,367961,218801,0,0,3.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,38,28,0,0,0,0,0,0,10,5.4,7.1,Moderate,47.9,11.2,1,0,26.3,1,0,39.2,117.2,145.0,0,N/A,1,55.7,117.1,2.76,123.1,888.0,0.163,7.07,11.03,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,32.2,57.8,35.3,7,3,7,Disability,3 |
| HC003-0000396,5.63,Male,Other,Asia_Pacific,Middle,A,Moderate,2.46,Intron22_inversion,1,1,Secondary,Recombinant_SHL,32.8,3x_week,14.6,8.1,0.561,140565,194846,0,1,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,13,22.8,0.0,Moderate,0.6,7.0,0,0,48.3,0,1,36.9,117.3,133.5,0,N/A,0,46.5,126.9,2.65,93.8,793.6,1.458,3.48,9.16,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.7,59.1,83.8,3,10,2,Employed_part,0 |
| HC003-0000397,0.67,Male,White_non_Hispanic,US,High,C,Mild,17.07,N/A,0,0,None_on_demand,Recombinant_EHL,27.5,Biweekly_EHL,1.0,19.6,0.674,284409,281095,1,0,25.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,26,20,0,0,0,0,0,0,19,26.9,32.1,None,73.9,9.9,0,0,33.6,0,0,36.2,95.4,127.2,0,N/A,1,82.9,98.5,2.25,8.6,411.7,0.293,5.63,7.07,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,29.0,58.7,22.7,15,5,15,Employed_full,0 |
| HC003-0000398,0.14,Male,White_non_Hispanic,Europe,High,A,Mild,25.66,Large_deletion,1,1,Primary,Recombinant_EHL,31.9,Weekly_EHL,10.6,17.4,0.657,110652,243508,0,0,9.7,1,Weekly,0.99,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,1,7,19.4,27.8,None,27.6,4.8,0,0,17.5,1,0,44.7,114.4,115.6,0,N/A,0,75.1,108.6,2.91,120.7,599.0,0.283,16.81,27.43,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,15,34.4,54.6,45.0,16,6,2,Employed_full,1 |
| HC003-0000399,0.68,Male,White_non_Hispanic,Europe,Low,A,Mild,22.73,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,24.4,3x_week,17.1,16.2,0.446,233204,162596,1,0,12.1,1,Biweekly,0.862,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,16,2.9,23.5,Moderate,29.6,22.6,0,0,24.9,0,1,23.4,107.0,145.0,0,N/A,0,60.4,114.6,2.27,158.4,745.0,0.606,2.79,45.3,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Liver_failure_HCV,0,0,34.2,72.4,62.8,18,8,8,Employed_full,0 |
| HC003-0000400,1.62,Male,Other,Europe,Middle,B,Moderate,1.19,Missense,0,1,Primary,Recombinant_SHL,18.3,Weekly_EHL,15.7,13.1,0.673,134830,301401,0,0,15.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,1,2,0,0,0,0,9,41.8,6.4,Moderate,34.0,9.8,1,1,57.4,1,0,59.6,108.1,111.6,0,N/A,0,57.3,87.1,2.61,61.4,473.3,0.154,7.05,7.44,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,38.7,56.8,43.4,0,3,0,Employed_full,2 |
| HC003-0000401,0.53,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_EHL,41.9,Every_other_day,4.2,24.2,0.767,256071,155389,1,0,22.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,19,22.7,8.0,Mild,0.0,4.5,1,0,13.4,1,0,33.1,104.2,112.1,0,N/A,0,73.3,133.3,1.42,78.0,455.7,0.746,9.7,6.75,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,32.6,53.5,65.0,9,0,11,Employed_full,0 |
| HC003-0000402,0.86,Male,Asian,Asia_Pacific,Middle,B,Moderate,1.12,Missense,0,1,Tertiary,Recombinant_EHL,40.4,Every_other_day,5.0,19.7,0.763,198660,203532,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,20,0.0,15.2,None,1.1,13.3,0,0,53.3,0,0,48.7,114.5,136.1,0,N/A,0,76.9,71.1,1.28,127.3,566.8,0.293,3.29,6.4,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,9,32.1,74.0,45.9,9,10,6,Disability,1 |
| HC003-0000403,2.84,Male,Black_non_Hispanic,Asia_Pacific,High,A,Severe,0.1,Small_indel,0,1,Tertiary,Plasma_derived,35.1,3x_week,7.9,8.0,0.664,131371,153956,1,0,2.9,0,N/A,0.0,0,1,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,1,7,17.5,4.8,Mild,37.2,15.4,0,0,37.0,0,1,43.0,97.6,111.9,0,N/A,1,69.6,96.3,2.28,128.3,712.0,0.1,17.96,4.26,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,6,45.8,48.2,80.1,3,6,2,Employed_full,3 |
| HC003-0000404,0.04,Male,Asian,US,Middle,A,Mild,10.2,Intron22_inversion,1,0,None_on_demand,Plasma_derived,24.9,Every_other_day,13.1,12.0,0.625,180715,226586,0,0,18.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,35,26,0,0,0,0,0,0,5,12.4,4.1,None,50.3,3.4,1,0,10.5,1,0,28.2,115.2,105.8,1,50.5,0,67.7,121.5,2.61,138.9,836.7,0.197,23.54,10.36,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.0,73.9,72.0,9,1,13,Employed_part,1 |
| HC003-0000405,3.55,Male,Other,US,High,A,Severe,0.1,Small_indel,0,1,Primary,Plasma_derived,25.6,3x_week,1.0,17.9,0.8,153201,149008,1,0,32.4,1,Weekly,0.74,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,1,11,15.1,23.7,Mild,12.2,0.0,0,0,20.2,1,0,57.5,107.7,123.0,0,N/A,0,51.7,70.4,2.88,135.6,691.8,0.125,10.75,23.21,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,40.0,36.0,65.9,0,9,15,Unemployed,6 |
| HC003-0000406,0.04,Male,Asian,Asia_Pacific,Middle,A,Moderate,4.96,Intron22_inversion,1,1,Secondary,Recombinant_SHL,39.1,Every_other_day,11.9,9.9,0.669,121984,409944,0,0,17.7,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,1,2,0,0,0,0,14,0.7,11.6,Moderate,5.1,0.7,1,0,45.0,0,1,55.0,96.4,136.4,0,N/A,0,53.0,124.4,2.31,33.7,1093.2,0.321,10.77,0.79,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.5,52.0,57.0,14,14,6,Disability,0 |
| HC003-0000407,1.92,Female,Other,Europe,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Recombinant_SHL,25.2,Biweekly_EHL,13.9,14.6,0.836,513830,493206,1,0,8.5,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,1,12,15.7,3.0,Mild,46.3,4.0,0,0,41.6,0,0,23.2,76.0,145.0,0,N/A,0,61.2,105.3,2.52,75.8,528.2,0.16,1.12,6.34,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,22,30.2,39.3,47.5,0,11,5,Employed_full,0 |
| HC003-0000408,0.12,Female,White_non_Hispanic,US,Middle,A,Severe,0.1,Missense,0,1,Primary,Plasma_derived,22.9,Weekly_EHL,10.3,10.6,0.63,216186,278443,0,0,1.0,1,Biweekly,0.874,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,9,7,1,2,0,0,0,0,8,5.0,19.6,Moderate,16.4,7.7,1,1,30.8,1,0,41.1,133.9,145.0,0,N/A,0,43.9,137.1,2.79,120.1,783.3,0.146,1.56,28.21,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,55.8,42.4,60.1,8,14,8,Employed_full,0 |
| HC003-0000409,0.64,Male,Black_non_Hispanic,US,Low,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,43.0,Weekly_EHL,15.2,12.2,0.672,71587,388733,0,0,29.4,0,N/A,0.0,0,0,0,1,11.8,High_titer,18,1,1,Low_dose,1,21,Emicizumab_bypass,0,22,16,0,0,0,0,0,1,12,10.8,7.4,Moderate,56.0,0.0,0,1,22.0,1,0,44.5,129.9,91.8,0,N/A,1,41.3,117.2,2.34,91.6,450.4,0.381,4.19,10.53,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,62.4,60.5,44.8,11,1,10,Disability,1 |
| HC003-0000410,1.17,Male,Hispanic,Latin_America,Low,A,Mild,20.64,Missense,0,0,None_on_demand,Recombinant_SHL,27.6,Weekly_EHL,13.3,15.6,0.456,184616,83316,1,1,9.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,18,14,0,0,0,0,0,0,13,19.6,0.0,Moderate,29.7,5.5,0,0,36.3,0,0,17.1,98.9,142.8,0,N/A,1,63.0,95.4,2.69,109.6,940.0,0.312,2.65,10.72,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,53.6,58.9,88.8,4,7,6,Disability,2 |
| HC003-0000411,4.35,Male,Hispanic,Latin_America,Middle,B,Mild,24.01,Splice_site,0,1,Secondary,Plasma_derived,42.1,Every_other_day,8.8,11.0,0.868,464551,88372,0,1,4.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,4,9.3,2.9,Mild,18.1,6.8,0,0,4.3,1,0,16.6,128.6,106.3,0,N/A,0,86.8,106.5,1.84,89.8,894.7,0.792,7.39,1.75,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,20.6,49.9,66.5,14,7,11,Unemployed,4 |
| HC003-0000412,0.43,Male,Asian,Europe,Low,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,16.8,Every_other_day,1.0,20.1,0.695,169937,153157,0,0,1.0,0,N/A,0.0,0,0,0,1,85.7,High_titer,21,1,1,High_dose,0,22,rFVIIa,0,23,17,0,0,0,0,0,0,0,11.5,7.9,None,66.1,9.9,0,0,51.3,0,1,32.0,94.5,107.2,1,60.0,1,25.0,107.5,1.57,77.6,778.1,0.765,0.46,13.9,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,0,0,32.7,72.3,49.8,0,6,14,Employed_full,1 |
| HC003-0000413,7.77,Male,Other,Other,High,A,Mild,14.36,Missense,0,0,None_on_demand,Recombinant_SHL,32.1,Weekly_EHL,12.8,16.3,0.794,659110,183618,0,0,1.0,1,Monthly,0.915,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,15,24.8,13.8,Moderate,9.9,11.7,0,1,54.7,1,0,26.2,108.9,114.3,1,36.9,0,56.4,156.7,2.13,85.3,337.5,0.316,7.36,18.32,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,47.8,67.3,83.9,7,5,11,Disability,2 |
| HC003-0000414,4.36,Male,Black_non_Hispanic,Europe,Low,C,Mild,26.44,N/A,0,1,Secondary,Recombinant_SHL,44.6,3x_week,6.3,12.1,0.509,160493,162901,0,0,6.5,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,1,22,4.3,13.4,Moderate,8.4,10.4,1,0,23.0,1,0,29.5,104.4,113.2,0,N/A,0,71.0,102.4,2.79,50.1,776.4,0.449,3.89,8.85,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,31.7,55.5,61.4,0,0,4,Employed_part,0 |
| HC003-0000415,0.16,Male,White_non_Hispanic,US,Low,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,28.2,3x_week,8.5,15.3,0.529,362959,79137,1,0,15.1,0,N/A,0.0,0,0,0,1,17.8,High_titer,19,1,0,N/A,0,0,aPCC,0,3,2,0,0,0,0,0,0,10,7.2,21.8,None,22.1,18.8,1,1,34.9,0,0,26.2,109.4,104.8,0,N/A,0,88.6,96.1,2.04,66.1,502.6,0.098,2.91,4.1,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,32.3,37.9,81.6,3,13,9,Employed_full,0 |
| HC003-0000416,0.02,Male,White_non_Hispanic,Europe,Middle,A,Mild,7.46,Intron22_inversion,1,1,Secondary,Recombinant_SHL,25.9,3x_week,14.9,9.9,0.6,499810,319910,0,0,3.5,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,50,0.0,10.1,Moderate,24.8,14.6,0,1,11.2,1,0,40.5,127.9,82.2,0,N/A,0,104.6,94.5,2.73,92.3,731.7,0.526,20.6,11.01,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,24.9,65.6,81.2,5,0,8,Disability,1 |
| HC003-0000417,0.34,Male,White_non_Hispanic,Europe,Low,A,Severe,0.1,Missense,0,1,Primary,Recombinant_EHL,18.7,3x_week,20.5,19.1,0.449,351553,528131,1,0,20.2,1,Biweekly,0.967,1,0,0,1,9.9,High_titer,22,0,1,Malmö,0,17,aPCC,0,0,0,0,0,0,0,0,0,5,5.1,8.3,Severe,38.0,9.3,0,0,43.1,0,0,31.3,107.0,145.0,1,35.0,0,59.3,105.3,1.89,93.1,388.2,0.418,3.5,2.9,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,1,24,36.0,51.2,68.1,4,10,17,Employed_full,0 |
| HC003-0000418,1.95,Male,White_non_Hispanic,US,High,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,36.7,Every_other_day,11.8,12.8,0.581,117630,341292,0,0,15.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,20,16.5,22.0,Moderate,0.0,2.2,1,1,12.1,1,0,55.4,108.2,140.2,0,N/A,0,108.4,68.2,2.11,117.7,698.6,0.646,1.23,2.58,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,31.0,58.9,44.2,13,6,13,Employed_full,0 |
| HC003-0000419,12.34,Male,White_non_Hispanic,US,Middle,A,Moderate,2.97,Intron22_inversion,1,1,Primary,Recombinant_SHL,21.8,3x_week,15.3,13.3,0.687,152439,309515,1,0,44.7,1,Biweekly,0.912,0,1,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,6,22.7,19.8,None,11.7,3.9,1,0,32.4,1,0,44.2,129.9,123.8,0,N/A,0,75.0,89.3,2.52,83.6,586.4,0.236,6.46,15.21,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,13.7,64.0,53.9,1,6,17,Unemployed,2 |
| HC003-0000420,0.71,Male,White_non_Hispanic,Europe,Low,A,Severe,0.1,Other,0,0,None_on_demand,Recombinant_EHL,27.2,3x_week,3.3,14.3,0.584,541470,201402,0,0,1.0,1,Biweekly,0.844,1,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,1,0,0,0,12,5.3,10.3,Moderate,30.9,0.0,0,0,13.9,0,0,51.5,116.2,106.7,0,N/A,0,82.9,71.7,2.07,162.0,509.9,0.237,6.08,19.81,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,52.7,52.0,100.0,0,5,4,Disability,0 |
| HC003-0000421,2.8,Male,White_non_Hispanic,Latin_America,Middle,A,Mild,16.78,Small_indel,0,0,None_on_demand,Recombinant_EHL,18.1,3x_week,13.5,17.6,0.603,165584,118007,1,0,19.9,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,21,16,0,0,0,0,0,1,3,22.3,14.3,None,69.9,8.9,1,1,43.1,1,0,21.7,103.2,145.0,0,N/A,0,41.6,75.3,2.15,144.2,756.7,0.239,3.9,3.79,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,44.6,68.8,54.3,5,7,9,Disability,0 |
| HC003-0000422,0.17,Male,Black_non_Hispanic,US,Middle,A,Mild,33.15,Small_indel,0,0,None_on_demand,Recombinant_EHL,40.5,Biweekly_EHL,11.6,21.7,0.583,481859,186514,0,0,20.1,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,50,38,0,0,0,0,0,0,8,16.3,8.2,None,0.0,10.0,0,0,49.0,0,0,34.5,119.8,122.9,0,N/A,0,75.0,122.5,1.1,74.9,640.8,0.949,29.4,2.59,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,25.3,52.2,58.4,8,9,4,Employed_full,0 |
| HC003-0000423,3.12,Male,White_non_Hispanic,Europe,Middle,A,Mild,14.07,Small_indel,0,0,None_on_demand,Recombinant_SHL,37.2,3x_week,19.4,10.7,0.692,207281,515449,1,0,5.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,8,6,0,0,0,1,0,0,2,0.0,2.7,None,60.3,13.4,0,0,18.1,1,0,43.6,134.9,113.7,1,28.0,1,84.8,100.7,2.82,102.9,613.1,0.378,5.3,3.35,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,49.5,61.4,55.4,10,10,11,Employed_full,0 |
| HC003-0000424,3.98,Male,Other,Europe,High,A,Moderate,2.42,Missense,0,0,None_on_demand,Recombinant_SHL,27.7,Weekly_EHL,8.8,14.9,0.746,292103,150845,0,0,19.1,1,Biweekly,0.823,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,18,17.1,29.6,Moderate,38.1,9.6,0,1,39.8,0,1,47.4,136.1,94.5,0,N/A,1,49.8,79.2,2.34,143.5,782.7,0.091,10.09,8.83,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,41.4,63.6,48.8,13,5,9,Unemployed,0 |
| HC003-0000425,4.43,Male,Hispanic,Europe,Middle,A,Moderate,2.1,Missense,0,1,Primary,Recombinant_EHL,18.8,Weekly_EHL,10.6,30.0,0.564,116814,143275,0,0,27.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,6,4,0,0,0,0,1,0,18,29.3,7.7,Mild,21.9,14.3,0,0,17.2,0,1,34.2,88.5,133.8,0,N/A,0,25.0,95.8,1.93,69.4,992.7,0.504,5.8,2.59,0,0,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,52.8,65.1,71.9,0,1,5,Unemployed,0 |
| HC003-0000426,4.5,Male,White_non_Hispanic,Latin_America,Middle,A,Mild,26.18,Small_indel,0,0,None_on_demand,Recombinant_SHL,40.3,Every_other_day,18.4,8.0,0.756,186286,312904,1,1,19.2,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,29,22,0,0,0,0,0,0,12,0.0,14.4,Mild,41.6,14.4,0,1,11.8,1,0,36.0,89.5,118.1,1,55.9,1,68.3,93.1,3.32,65.1,699.6,0.208,12.38,23.46,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,48.1,73.4,43.3,15,1,7,Disability,8 |
| HC003-0000427,3.29,Male,White_non_Hispanic,Asia_Pacific,Middle,B,Severe,0.1,Nonsense,0,1,Primary,Recombinant_EHL,25.1,Weekly_EHL,11.4,23.5,0.547,158707,323464,1,0,34.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,7,39.1,0.0,None,6.2,1.8,0,0,41.5,1,0,37.3,135.0,128.8,0,N/A,0,60.3,101.5,2.01,147.0,324.9,0.717,3.44,4.86,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,31.5,47.8,50.4,3,10,3,Employed_part,0 |
| HC003-0000428,0.17,Male,White_non_Hispanic,Latin_America,Middle,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,19.2,3x_week,5.3,17.8,0.567,307232,117718,0,0,1.0,0,N/A,0.0,0,0,1,0,0.0,None,0,1,0,N/A,0,0,N/A,0,28,21,0,0,0,0,0,0,1,7.7,17.9,Mild,58.1,4.9,0,0,33.8,0,1,38.4,109.2,127.1,0,N/A,1,94.6,57.8,2.14,122.7,369.5,0.463,1.91,10.27,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,47.4,44.7,66.3,6,5,7,Employed_full,1 |
| HC003-0000429,1.65,Male,Other,US,High,A,Moderate,4.92,Intron22_inversion,1,1,Tertiary,Recombinant_SHL,13.9,3x_week,27.3,13.9,0.796,283770,157827,1,0,7.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,18,0.0,2.4,Mild,15.0,7.9,0,0,19.4,0,1,65.0,71.0,135.5,1,37.2,0,53.2,69.4,1.92,138.0,662.4,0.812,8.27,3.79,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,47.8,52.8,58.5,7,2,4,Employed_full,0 |
| HC003-0000430,0.87,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_SHL,22.8,Every_other_day,5.5,8.5,0.928,354190,139951,0,0,35.7,1,Weekly,0.914,0,0,0,1,46.6,High_titer,7,0,1,Low_dose,1,23,rFVIIa,0,0,0,0,0,0,0,0,0,19,16.7,25.4,Mild,12.7,3.8,0,0,18.6,1,0,45.8,100.4,128.0,0,N/A,1,49.5,59.6,2.95,107.6,834.8,0.691,5.69,12.5,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,51.6,80.0,64.3,0,3,5,Employed_full,0 |
| HC003-0000431,0.94,Male,White_non_Hispanic,Europe,Middle,A,Severe,0.1,Missense,0,1,Primary,Recombinant_SHL,16.4,Biweekly_EHL,11.6,12.9,0.841,199923,186250,0,0,28.9,1,Weekly,0.826,0,0,0,1,4.4,Low_titer,16,0,0,N/A,0,0,aPCC,0,3,2,0,0,0,0,0,0,20,25.0,26.4,None,23.4,6.5,0,0,12.4,0,0,42.5,106.2,118.6,0,N/A,0,39.2,74.8,3.12,84.8,674.2,0.638,8.47,13.45,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,51.0,69.5,61.6,5,6,13,Employed_part,7 |
| HC003-0000432,4.47,Male,Other,US,Middle,A,Severe,0.1,Large_deletion,1,1,Secondary,Recombinant_SHL,23.0,Biweekly_EHL,14.1,12.4,0.823,153562,312339,0,0,24.5,0,N/A,0.0,0,0,0,1,86.6,High_titer,11,1,1,Low_dose,1,13,rFVIIa,0,4,3,0,0,0,0,0,0,13,11.6,16.5,None,22.2,9.8,1,0,41.3,0,0,26.9,108.7,134.1,0,N/A,0,51.1,79.8,3.07,41.3,742.1,0.746,2.74,1.63,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,62.9,50.5,45.6,12,1,5,Employed_full,3 |
| HC003-0000433,4.31,Male,Other,US,Middle,A,Moderate,2.01,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,34.0,Every_other_day,13.6,20.6,0.398,299430,120329,1,0,32.8,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,15,11,0,0,0,0,0,0,5,18.7,12.9,None,10.4,7.3,1,0,42.6,1,0,27.2,130.3,141.2,0,N/A,0,123.7,71.0,3.06,100.5,639.4,0.578,6.58,4.01,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,30,50.5,52.5,82.5,10,6,4,Employed_part,2 |
| HC003-0000434,2.34,Male,White_non_Hispanic,US,High,C,Severe,0.1,N/A,0,1,Tertiary,Recombinant_EHL,25.0,Every_other_day,10.9,18.1,0.627,144675,310157,1,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,1,0,0,8,40.4,10.5,Moderate,5.1,8.0,1,0,29.3,0,1,39.4,96.4,145.0,0,N/A,0,30.1,121.4,2.1,144.3,823.2,0.173,1.25,6.42,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,1,31.4,55.8,78.0,4,11,3,Employed_part,0 |
| HC003-0000435,0.5,Male,White_non_Hispanic,Europe,Low,A,Severe,0.1,Intron22_inversion,1,1,Tertiary,Recombinant_SHL,30.8,Every_other_day,10.9,12.5,0.453,512499,189250,1,0,27.5,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,1,11,17.5,11.6,Mild,1.8,2.3,1,0,18.4,1,1,55.6,133.7,103.9,0,N/A,1,35.6,151.5,3.24,144.8,761.0,0.121,3.05,4.61,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,13,42.0,58.7,48.6,8,6,9,Employed_full,0 |
| HC003-0000436,2.2,Male,White_non_Hispanic,Europe,Low,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_EHL,22.2,Weekly_EHL,10.6,18.3,0.58,250518,575558,0,0,30.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,1,12,50.8,15.3,Moderate,1.4,11.0,0,0,18.0,0,0,39.6,120.7,144.1,0,N/A,0,63.8,123.1,2.3,137.8,466.5,0.155,2.55,16.19,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,28.5,62.4,68.7,9,0,9,Disability,0 |
| HC003-0000437,0.57,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Large_deletion,1,1,Primary,Recombinant_SHL,28.5,3x_week,5.3,11.0,0.363,220647,210958,0,0,10.1,0,N/A,0.0,0,0,0,1,8.8,High_titer,17,1,0,N/A,0,0,aPCC,0,1,1,0,0,0,0,0,0,20,30.2,12.7,Mild,16.3,10.6,1,0,17.8,0,0,40.1,89.3,95.5,0,N/A,0,108.4,84.2,1.63,126.5,730.6,0.54,6.66,4.32,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,5,53.3,62.8,55.1,6,9,4,Employed_full,0 |
| HC003-0000438,2.97,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Mild,19.35,Missense,0,1,Secondary,Recombinant_EHL,43.4,Every_other_day,24.9,22.4,0.614,354090,171363,1,1,49.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,8,6,0,0,0,0,0,0,11,15.6,19.9,None,20.6,3.4,0,0,23.2,0,0,33.1,108.6,142.4,0,N/A,0,81.3,105.9,2.19,183.4,372.3,0.051,3.04,14.06,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,30.6,68.0,77.2,9,10,10,Employed_full,0 |
| HC003-0000439,0.39,Male,Hispanic,Other,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_SHL,25.2,Weekly_EHL,10.7,16.9,0.618,256320,239751,1,1,20.4,1,Biweekly,0.836,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,18,18.5,4.7,None,9.8,0.2,0,1,36.6,0,0,21.1,124.9,113.5,0,N/A,0,99.2,98.1,2.56,32.9,730.6,0.298,1.49,11.43,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,64.5,76.0,74.0,3,11,7,Employed_full,3 |
| HC003-0000440,2.37,Male,Asian,US,Low,A,Mild,16.08,Small_indel,0,0,None_on_demand,Recombinant_EHL,31.1,3x_week,15.6,22.0,0.603,99227,151968,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,13,10,0,0,0,0,0,0,34,11.2,24.2,None,0.0,15.4,1,0,20.5,1,0,47.2,115.8,139.2,0,N/A,0,56.5,83.0,2.08,104.2,599.1,0.243,2.84,6.7,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,0,0,36.8,54.7,79.6,2,6,5,Employed_full,0 |
| HC003-0000441,0.95,Male,Hispanic,Other,Middle,A,Mild,37.06,Missense,0,0,None_on_demand,Recombinant_EHL,15.5,3x_week,10.0,16.4,0.735,141937,73303,0,0,22.6,0,N/A,0.0,1,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,31,23,0,0,0,0,0,0,5,18.0,8.6,Mild,32.0,18.5,0,1,24.3,0,0,38.9,122.6,145.0,0,N/A,0,34.4,137.1,2.47,57.5,678.9,0.802,7.23,14.6,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,39.5,53.9,48.7,6,15,7,Disability,6 |
| HC003-0000442,0.19,Male,Hispanic,US,Middle,B,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_SHL,40.2,3x_week,9.9,11.0,0.523,506169,159490,0,0,9.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,14,10,0,0,0,0,0,0,10,21.7,6.0,Moderate,58.2,9.4,0,0,15.6,0,0,47.4,103.3,128.2,0,N/A,1,55.1,156.2,2.67,157.1,708.3,0.274,4.98,1.85,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Surgical_complication,0,0,34.9,52.4,43.0,0,9,10,Disability,1 |
| HC003-0000443,2.76,Male,White_non_Hispanic,Other,Middle,B,Mild,17.01,Missense,0,0,None_on_demand,Recombinant_SHL,24.2,3x_week,9.3,8.0,0.879,282189,158238,0,0,32.0,0,N/A,0.0,0,0,0,1,56.5,High_titer,16,0,1,Low_dose,1,13,rFVIIa,0,50,38,0,0,0,0,0,0,7,10.2,14.9,None,44.2,5.8,1,0,3.6,1,0,43.9,126.1,124.1,1,62.0,1,62.3,58.8,2.61,72.9,700.7,0.224,2.47,6.99,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,32.1,53.2,36.0,10,18,19,Employed_full,1 |
| HC003-0000444,0.25,Male,Black_non_Hispanic,Other,Middle,A,Mild,13.28,Missense,0,1,Tertiary,Recombinant_EHL,36.4,3x_week,2.7,25.3,0.863,97837,81133,1,0,24.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,1,24,0.0,15.4,Mild,4.5,14.3,1,0,18.0,1,0,30.4,107.0,123.2,0,N/A,0,65.2,140.3,2.73,135.3,905.1,0.863,8.77,3.68,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.2,59.7,99.5,7,11,3,Employed_full,2 |
| HC003-0000445,8.55,Male,Hispanic,US,Middle,A,Moderate,3.9,Intron22_inversion,1,1,Secondary,Recombinant_SHL,27.0,Every_other_day,11.0,15.0,0.915,331462,173422,1,0,10.8,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,8,6,0,0,0,0,0,0,13,30.9,0.0,None,24.0,10.8,1,0,55.1,1,0,44.7,140.0,116.5,1,71.3,1,60.3,83.5,2.31,77.0,656.1,0.28,15.68,6.71,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,42.5,62.4,74.7,6,11,15,Employed_full,1 |
| HC003-0000446,1.32,Male,Asian,Latin_America,Middle,A,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_EHL,32.9,3x_week,9.6,19.7,0.891,191845,63988,0,0,36.0,1,Biweekly,0.739,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,8,6,0,0,0,0,0,1,6,26.7,8.2,None,55.5,6.7,0,1,10.5,0,0,26.5,88.6,145.0,0,N/A,1,78.0,92.7,2.04,111.8,684.0,0.246,9.27,4.84,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,40.2,73.3,79.4,11,4,5,Employed_full,0 |
| HC003-0000447,0.71,Male,Other,Other,Middle,B,Severe,0.1,Nonsense,0,1,Primary,Non_factor,33.4,Biweekly_EHL,19.0,21.4,0.671,158784,151169,0,0,29.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,25,0.0,0.0,Mild,5.0,13.8,0,0,29.7,1,0,44.6,140.0,123.1,0,N/A,0,49.3,107.9,1.66,90.7,889.4,0.204,0.71,7.8,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,5,35.3,48.9,41.9,9,2,5,Employed_full,0 |
| HC003-0000448,0.4,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Mild,36.83,Small_indel,0,0,None_on_demand,Recombinant_EHL,24.4,3x_week,4.8,15.5,0.693,135006,203170,0,0,8.1,1,Biweekly,0.95,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,16,17.1,6.6,None,49.3,3.1,0,1,14.0,1,0,41.2,96.0,85.8,0,N/A,0,44.6,143.3,2.36,94.4,991.4,0.379,5.42,7.45,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,43.4,59.6,70.9,12,6,15,Employed_full,0 |
| HC003-0000449,1.46,Male,White_non_Hispanic,Other,Middle,A,Mild,31.11,Missense,0,1,Primary,Recombinant_SHL,36.7,Biweekly_EHL,8.5,15.6,0.505,488922,188810,0,1,16.2,1,Weekly,0.907,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,23,27.3,6.9,None,34.5,3.9,0,0,27.3,0,0,60.5,140.0,140.9,0,N/A,0,38.5,107.9,2.13,108.3,646.8,0.231,4.0,8.37,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.0,47.6,37.9,15,5,8,Disability,0 |
| HC003-0000450,2.78,Male,White_non_Hispanic,Europe,Middle,A,Mild,28.86,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,21.9,3x_week,6.6,17.9,0.829,82512,146454,0,0,24.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,16,12,0,0,0,0,0,1,29,26.1,14.4,Moderate,14.0,10.2,0,0,7.3,0,0,31.6,131.5,140.0,0,N/A,0,69.5,111.5,2.34,131.8,557.8,0.232,0.88,8.68,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,15,39.9,60.0,68.4,9,4,6,Unemployed,2 |
| HC003-0000451,3.55,Male,White_non_Hispanic,US,Low,A,Mild,6.73,Large_deletion,1,0,None_on_demand,Non_factor,34.2,Weekly_EHL,20.7,16.9,0.575,162345,172342,0,0,13.6,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,24,18,0,0,0,0,0,0,7,6.7,5.7,Mild,78.0,8.7,0,0,27.2,1,0,26.1,96.8,125.8,0,N/A,0,67.3,123.9,1.36,90.6,566.7,0.961,1.6,12.38,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,8,59.4,80.0,62.3,3,5,14,Disability,0 |
| HC003-0000452,1.76,Male,Other,Asia_Pacific,Middle,A,Severe,0.1,Small_indel,0,1,Secondary,Recombinant_SHL,24.9,Every_other_day,6.8,11.0,0.946,288392,121536,0,1,14.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,1,17,26.8,7.6,None,16.1,11.8,1,0,51.4,0,0,37.0,127.0,110.8,0,N/A,0,89.0,128.3,1.64,130.7,731.1,0.313,8.49,2.38,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,33.7,54.6,57.8,11,5,18,Employed_full,2 |
| HC003-0000453,6.78,Male,White_non_Hispanic,Europe,Middle,B,Mild,9.59,Missense,0,0,None_on_demand,Plasma_derived,30.8,Weekly_EHL,15.4,14.3,0.574,691776,180847,0,0,18.4,1,Weekly,0.865,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,8,6,0,0,0,0,0,0,18,15.2,22.4,Moderate,10.0,15.2,0,0,13.7,0,0,49.3,105.1,104.1,0,N/A,0,99.0,114.3,2.65,136.5,613.4,0.21,5.2,11.69,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,36.7,80.0,54.4,3,3,7,Employed_full,3 |
| HC003-0000454,3.1,Male,Black_non_Hispanic,Europe,High,A,Moderate,2.14,Intron22_inversion,1,1,Primary,Plasma_derived,24.3,Every_other_day,17.8,14.4,0.695,374114,185173,0,0,5.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,13,19.7,28.5,None,11.7,0.0,0,1,25.3,0,0,10.0,120.5,110.9,1,46.8,0,38.4,128.5,1.58,78.3,335.1,0.136,4.78,1.89,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,29,27.3,47.6,78.5,3,9,5,Employed_part,3 |
| HC003-0000455,0.36,Male,Hispanic,Europe,Middle,B,Mild,27.34,Missense,0,1,Primary,Recombinant_EHL,28.4,Every_other_day,11.1,21.3,0.616,161520,114677,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,29,4.0,4.6,Moderate,16.7,8.2,0,0,29.9,1,0,52.5,118.0,128.6,1,42.5,0,65.5,83.3,2.3,170.4,852.1,0.353,2.66,0.6,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,0,0,36.3,51.4,54.7,6,3,7,Disability,1 |
| HC003-0000456,6.47,Male,White_non_Hispanic,Europe,Low,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,19.4,Every_other_day,3.7,10.9,0.627,671730,205633,0,0,20.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,14,10,0,0,0,0,0,1,15,0.0,20.2,Moderate,59.0,19.4,0,1,12.7,1,0,39.5,108.0,91.8,0,N/A,0,60.5,51.4,1.98,124.8,796.8,0.192,10.65,43.61,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,1,22,44.1,52.6,80.9,13,6,2,Employed_full,3 |
| HC003-0000457,0.81,Male,White_non_Hispanic,US,Middle,A,Severe,0.1,Small_indel,0,1,Primary,Recombinant_SHL,30.0,Every_other_day,3.8,15.4,0.882,119006,204992,1,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,9,5.7,15.1,None,26.1,4.4,1,1,10.8,1,0,28.3,106.4,132.6,0,N/A,0,31.2,151.1,1.95,77.7,856.4,0.224,1.68,3.17,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,10,34.2,57.7,61.3,11,1,6,Employed_full,2 |
| HC003-0000458,6.8,Male,Hispanic,Latin_America,Low,A,Mild,12.33,Small_indel,0,0,None_on_demand,Recombinant_SHL,28.4,Biweekly_EHL,17.2,17.0,0.588,314645,165528,1,0,6.1,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,0,10,21.4,0.0,Mild,5.4,3.7,0,1,11.8,1,0,37.6,121.8,126.3,0,N/A,0,53.4,70.9,2.44,119.6,891.9,0.152,2.2,4.94,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,15,27.5,54.5,67.2,11,6,5,Employed_part,1 |
| HC003-0000459,0.62,Male,Hispanic,US,Middle,A,Mild,12.9,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,23.7,Biweekly_EHL,4.4,13.3,0.603,359572,603513,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,8,6,0,0,0,0,0,0,11,12.5,5.7,None,0.5,0.0,0,0,25.5,1,0,33.1,96.9,145.0,0,N/A,0,99.5,85.1,2.41,136.5,684.3,0.353,3.48,1.38,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,44.0,63.6,69.7,8,7,9,Employed_part,0 |
| HC003-0000460,1.05,Male,White_non_Hispanic,Latin_America,High,A,Mild,32.27,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,27.6,Weekly_EHL,14.4,11.2,0.733,158155,167653,1,0,1.0,1,Biweekly,0.795,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,29,22.8,0.0,Moderate,0.0,8.6,0,0,6.8,0,0,27.3,97.7,137.6,0,N/A,0,51.1,90.7,2.67,118.6,696.9,0.106,1.32,4.91,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,45.1,28.5,68.4,10,2,4,Employed_part,0 |
| HC003-0000461,2.29,Male,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_EHL,29.1,Every_other_day,12.7,17.0,0.781,407810,156433,0,0,23.1,1,Biweekly,0.774,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,6,4,0,0,0,0,0,1,2,28.3,14.6,None,3.6,11.5,0,0,59.4,0,0,18.7,134.1,112.0,0,N/A,0,47.4,85.9,1.85,103.1,831.2,0.419,2.21,8.9,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,31,46.8,46.2,65.2,10,6,14,Disability,3 |
| HC003-0000462,0.15,Male,Black_non_Hispanic,Europe,Middle,A,Severe,0.1,Missense,0,1,Tertiary,Recombinant_EHL,23.1,Weekly_EHL,14.3,19.0,0.758,197139,145627,1,0,15.3,0,N/A,0.0,1,0,0,1,31.1,High_titer,20,0,1,High_dose,1,15,Emicizumab_bypass,0,9,7,0,0,0,0,0,0,28,11.0,3.4,Moderate,10.4,11.5,0,0,37.1,0,1,50.8,123.6,94.6,0,N/A,0,63.9,79.7,1.96,5.0,431.3,0.195,10.48,9.19,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,15,26.4,74.9,92.1,4,6,4,Disability,0 |
| HC003-0000463,5.27,Male,White_non_Hispanic,Europe,Middle,A,Mild,15.01,Other,0,0,None_on_demand,Non_factor,27.0,Weekly_EHL,14.8,13.8,0.722,407210,110695,0,0,14.9,1,Biweekly,0.99,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,4,9.9,13.1,None,33.3,1.8,0,0,51.9,0,0,35.3,88.9,110.2,0,N/A,0,85.1,113.0,2.96,56.3,586.6,0.534,2.28,2.49,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,55.1,41.9,77.8,10,4,7,Employed_full,4 |
| HC003-0000464,0.9,Male,Other,US,Middle,A,Severe,0.1,Intron22_inversion,1,1,Secondary,Recombinant_EHL,20.0,3x_week,6.4,19.5,0.645,88987,253457,0,0,2.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,15,0.0,32.6,Moderate,8.0,7.9,1,0,42.2,0,1,37.3,94.9,145.0,0,N/A,1,58.3,113.3,2.29,122.1,639.3,0.444,8.37,4.96,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,16,34.6,52.4,26.2,7,4,3,Unemployed,1 |
| HC003-0000465,0.52,Male,White_non_Hispanic,Other,High,A,Severe,0.1,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,46.8,3x_week,6.1,13.3,0.834,328071,127628,1,0,10.1,1,Monthly,0.857,0,0,0,1,17.0,High_titer,25,1,1,High_dose,1,8,aPCC,0,2,2,0,0,0,0,0,0,3,0.0,24.7,Severe,10.1,9.3,1,1,12.9,0,1,52.1,72.3,130.3,0,N/A,0,67.8,117.4,2.58,55.5,815.9,0.327,7.45,10.3,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,28.9,62.1,59.1,5,8,4,Employed_full,0 |
| HC003-0000466,0.12,Male,White_non_Hispanic,Latin_America,Middle,A,Moderate,1.28,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,36.5,Weekly_EHL,16.3,15.8,0.468,209554,135405,1,0,22.5,0,N/A,0.0,0,0,0,1,11.7,High_titer,22,1,1,Malmö,0,28,Emicizumab_bypass,0,19,14,0,0,0,0,0,0,8,0.0,5.9,None,13.9,8.3,1,0,34.7,1,0,42.7,133.2,135.8,0,N/A,0,25.0,115.6,2.15,115.6,553.1,0.593,3.92,9.16,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,51.3,55.5,82.8,5,6,12,Employed_part,0 |
| HC003-0000467,0.05,Male,White_non_Hispanic,Europe,Middle,B,Severe,0.1,Missense,0,1,Tertiary,Plasma_derived,30.2,Every_other_day,8.2,17.3,0.409,534893,137431,0,0,17.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,7,21.7,3.9,Mild,11.4,1.4,1,0,26.9,0,0,23.3,128.8,113.7,0,N/A,0,77.6,88.3,2.63,130.4,521.8,1.047,1.44,8.29,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,54.7,47.5,50.6,4,10,8,Disability,0 |
| HC003-0000468,0.06,Male,White_non_Hispanic,US,Middle,A,Moderate,3.73,Large_deletion,1,1,Secondary,Non_factor,37.4,3x_week,1.0,20.8,0.604,261349,109922,0,0,27.9,1,Biweekly,0.833,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,17,11.2,22.3,Mild,33.6,8.5,0,0,32.9,0,0,50.1,93.2,133.7,1,32.8,0,69.9,88.3,1.16,90.5,572.4,0.831,4.71,14.65,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,36.5,60.5,62.1,6,2,6,Employed_full,2 |
| HC003-0000469,0.76,Male,White_non_Hispanic,US,Low,B,Severe,0.1,Missense,0,0,None_on_demand,Recombinant_SHL,12.2,Weekly_EHL,15.9,11.7,0.596,567807,74941,0,0,29.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,38,28,0,0,0,0,0,0,0,8.6,4.0,Mild,41.7,3.1,1,0,29.9,1,0,59.8,128.0,97.6,0,N/A,0,84.5,131.3,2.98,24.4,734.5,0.106,0.83,6.7,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,10,30.8,64.4,63.1,7,5,5,Employed_full,1 |
| HC003-0000470,0.73,Male,White_non_Hispanic,Europe,Low,A,Mild,7.51,Missense,0,0,None_on_demand,Recombinant_EHL,10.0,Every_other_day,5.8,12.0,0.458,363876,142704,1,0,15.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,19,14,0,0,0,0,1,0,23,7.2,19.9,None,4.4,0.0,0,0,39.5,1,1,48.0,140.0,141.8,0,N/A,0,25.0,85.4,2.17,65.5,637.7,0.186,2.94,25.87,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,CNS_bleed,0,0,44.9,50.0,84.3,10,4,7,Unemployed,3 |
| HC003-0000471,2.04,Male,Other,Other,Low,A,Mild,6.28,Large_deletion,1,0,None_on_demand,Recombinant_EHL,24.8,3x_week,14.8,27.1,0.763,248574,278359,1,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,17,13,0,0,0,0,0,0,31,5.7,33.9,Mild,37.0,12.1,0,0,61.5,0,0,31.6,84.2,104.2,1,52.2,0,58.3,84.8,1.78,122.4,388.9,0.205,5.44,5.68,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,25.3,60.1,47.3,15,6,5,Employed_full,2 |
| HC003-0000472,4.58,Male,White_non_Hispanic,Latin_America,Middle,A,Mild,20.51,Intron22_inversion,1,1,Secondary,Recombinant_SHL,17.0,3x_week,20.4,8.0,0.855,430457,198489,1,0,8.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,17,26.1,17.4,Moderate,12.6,8.8,0,0,53.4,1,0,24.3,102.7,89.5,1,35.8,0,86.2,126.0,1.87,145.3,424.4,0.502,8.99,13.81,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,68.1,64.6,49.4,10,7,7,Employed_full,0 |
| HC003-0000473,2.35,Male,White_non_Hispanic,US,High,B,Moderate,1.01,Missense,0,0,None_on_demand,Recombinant_EHL,26.1,Weekly_EHL,12.1,21.8,0.422,432110,392498,1,0,16.8,1,Weekly,0.942,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,18,16.1,21.5,Severe,0.0,11.6,0,0,8.3,0,0,31.2,83.8,145.0,0,N/A,0,52.7,99.5,2.27,11.7,674.6,0.198,3.97,14.26,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,28.6,66.8,69.1,8,1,13,Employed_full,2 |
| HC003-0000474,2.18,Female,White_non_Hispanic,Asia_Pacific,Middle,A,Severe,0.1,Intron22_inversion,1,1,Primary,Plasma_derived,29.6,Biweekly_EHL,18.0,13.3,0.829,356164,261837,0,0,8.7,1,Biweekly,0.99,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,1,1,1,15,26.9,20.5,Moderate,0.0,4.8,0,0,23.7,1,1,43.2,134.0,127.4,0,N/A,0,66.1,85.9,2.34,98.2,680.6,0.192,2.76,1.69,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,43.9,59.7,66.8,0,8,16,Disability,2 |
| HC003-0000475,1.11,Male,White_non_Hispanic,Europe,Low,A,Mild,26.6,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,35.4,Weekly_EHL,12.9,11.2,0.538,67820,233744,1,0,5.3,1,Weekly,0.976,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,5,4,0,0,0,0,0,0,18,0.0,7.5,Mild,46.8,11.8,0,0,41.5,0,0,59.1,113.1,126.9,0,N/A,0,56.0,86.1,2.47,36.3,655.0,0.167,2.58,10.99,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,38.2,73.1,69.3,19,15,12,Disability,3 |
| HC003-0000476,1.94,Male,Hispanic,Asia_Pacific,Low,A,Mild,35.41,Missense,0,0,None_on_demand,Recombinant_SHL,18.9,3x_week,21.5,11.7,0.68,148816,461079,1,0,18.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,9,7,0,0,0,0,0,0,1,21.4,14.3,None,15.8,14.1,0,0,24.4,1,0,32.9,107.0,91.3,0,N/A,0,56.5,131.5,1.8,98.6,565.3,0.383,3.08,4.15,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,29.9,56.5,66.5,3,7,9,Unemployed,0 |
| HC003-0000477,1.6,Male,White_non_Hispanic,US,Middle,A,Moderate,3.7,Small_indel,0,0,None_on_demand,Recombinant_SHL,31.2,3x_week,5.6,14.3,0.493,615668,171344,0,0,47.2,1,Weekly,0.967,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,4,3,0,0,0,0,0,0,9,9.2,4.3,None,0.0,18.5,1,1,14.7,1,0,34.2,119.5,136.2,0,N/A,0,90.7,116.4,2.84,88.7,791.8,0.5,7.38,2.98,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,29.7,46.2,60.3,4,3,4,Employed_part,1 |
| HC003-0000478,0.11,Male,Hispanic,Europe,High,A,Mild,8.88,Small_indel,0,0,None_on_demand,Recombinant_SHL,28.1,3x_week,12.0,8.6,0.725,126302,185635,0,0,12.1,1,Biweekly,0.816,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,1,22,11.6,22.3,Mild,11.9,12.9,0,0,42.6,0,0,54.3,103.9,140.9,0,N/A,0,33.7,106.6,2.14,189.4,716.4,0.114,5.93,5.04,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,7,52.4,53.8,69.8,13,5,6,Employed_full,1 |
| HC003-0000479,0.54,Male,White_non_Hispanic,Other,Middle,A,Mild,11.88,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,30.8,3x_week,16.0,18.1,0.52,455648,178844,0,0,18.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,19,14,0,0,0,0,0,0,12,31.2,3.3,Mild,57.3,10.3,1,0,45.6,1,0,36.8,107.0,121.4,0,N/A,0,63.9,67.3,2.11,73.4,710.3,0.2,4.4,8.55,1,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,44.0,68.1,64.9,1,5,10,Disability,0 |
| HC003-0000480,0.52,Male,Other,US,Middle,A,Mild,23.54,Missense,0,0,None_on_demand,Recombinant_SHL,23.8,Every_other_day,10.9,14.1,0.706,409983,389217,0,0,2.3,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,47,35,0,0,0,1,0,0,5,10.3,17.6,Moderate,33.3,0.0,1,1,50.5,1,0,62.6,120.5,141.0,1,32.8,0,70.5,106.7,2.29,137.0,716.7,0.066,7.42,1.81,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,1,0,N/A,0,N/A,0,0,32.3,47.1,58.5,9,3,12,Employed_full,0 |
| HC003-0000481,0.15,Male,White_non_Hispanic,Latin_America,High,A,Mild,17.74,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,39.1,Weekly_EHL,18.9,8.0,0.66,173607,180098,0,0,32.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,15,11,0,0,0,0,0,0,10,20.9,21.1,Mild,40.3,7.4,1,1,22.7,1,1,40.2,102.8,145.0,0,N/A,0,85.6,94.0,2.73,135.4,937.5,0.044,4.48,7.57,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,16,33.8,33.6,61.1,5,9,14,Unemployed,3 |
| HC003-0000482,0.91,Male,Asian,Other,Low,A,Severe,0.1,Missense,0,1,Secondary,Recombinant_EHL,27.2,Weekly_EHL,9.4,22.5,0.601,81053,130074,1,0,28.5,1,Weekly,0.793,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,9,2.8,8.1,None,10.3,0.0,0,0,47.1,1,0,56.0,105.6,134.5,0,N/A,0,62.3,74.5,2.38,87.2,465.6,0.444,1.54,6.07,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,20,31.0,60.6,54.4,6,0,7,Employed_part,0 |
| HC003-0000483,0.12,Male,White_non_Hispanic,US,Middle,A,Moderate,2.0,Missense,0,1,Primary,Recombinant_EHL,42.2,3x_week,24.4,14.2,0.767,190737,241310,1,0,27.7,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,8,6,0,0,0,1,0,0,6,15.4,6.2,None,11.0,3.1,1,1,23.7,1,1,46.6,111.9,86.0,0,N/A,1,86.3,83.2,2.13,99.8,574.2,0.388,1.84,18.81,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,49.7,51.6,52.1,7,7,10,Employed_full,2 |
| HC003-0000484,3.01,Male,White_non_Hispanic,US,High,A,Moderate,3.98,Large_deletion,1,0,None_on_demand,Plasma_derived,21.7,Weekly_EHL,24.7,11.6,0.901,933605,119595,0,0,34.3,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,42,32,0,0,0,0,0,0,14,0.0,10.6,Mild,0.0,19.7,0,1,17.1,1,0,50.5,116.8,104.3,0,N/A,0,63.8,119.5,2.24,95.0,589.5,0.346,7.25,4.18,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,50.1,78.5,69.8,1,11,9,Employed_full,1 |
| HC003-0000485,3.08,Male,Asian,Latin_America,Middle,B,Severe,0.1,Nonsense,0,1,Primary,Recombinant_EHL,33.9,Weekly_EHL,13.7,28.0,0.633,159857,234858,0,0,12.9,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,1,1,0,0,0,0,0,0,6,14.3,4.9,None,10.8,1.9,0,0,74.7,1,0,39.9,127.0,145.0,0,N/A,0,67.6,134.8,3.01,65.2,876.4,1.072,1.49,21.56,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,7,45.8,58.7,43.7,6,11,8,Employed_part,2 |
| HC003-0000486,0.22,Male,Hispanic,US,Low,A,Mild,21.89,Missense,0,0,None_on_demand,Plasma_derived,27.5,3x_week,15.3,16.3,0.8,166616,221222,0,0,14.4,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,19,14,0,0,0,0,0,0,6,19.6,13.3,None,77.0,0.0,1,0,30.8,0,0,40.7,126.7,126.5,1,39.8,0,66.8,70.4,2.93,61.8,582.7,0.079,3.3,10.47,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.8,68.4,71.6,12,10,12,Unemployed,4 |
| HC003-0000487,0.17,Male,Black_non_Hispanic,US,High,A,Mild,37.34,Intron22_inversion,1,1,Primary,Recombinant_SHL,25.4,Every_other_day,19.2,8.5,0.818,147480,163619,0,1,38.5,1,Weekly,0.908,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,10,8,0,0,0,0,0,0,8,28.3,4.7,None,2.1,12.9,0,1,2.8,0,0,47.0,85.0,126.6,0,N/A,0,79.4,73.9,2.58,78.6,507.4,0.057,4.09,7.17,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,13,46.9,51.1,58.3,7,3,4,Unemployed,0 |
| HC003-0000488,6.26,Male,White_non_Hispanic,Europe,High,A,Severe,0.1,Small_indel,0,0,None_on_demand,Recombinant_SHL,33.1,Every_other_day,4.9,8.0,0.531,556193,238686,0,0,25.6,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,12,9,0,0,0,0,0,1,4,5.2,5.2,Mild,23.0,4.0,0,0,15.7,1,0,51.6,140.0,110.0,0,N/A,0,76.9,119.4,2.47,49.5,631.0,0.123,1.96,23.25,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,21.9,61.9,60.6,24,12,10,Employed_full,0 |
| HC003-0000489,0.63,Male,Hispanic,Latin_America,Middle,A,Mild,24.07,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,25.6,3x_week,4.1,23.7,0.736,231944,85486,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,10,8,0,0,0,0,0,0,7,8.7,16.4,None,27.4,12.6,0,1,24.4,0,0,48.3,116.2,113.5,0,N/A,0,40.5,88.5,3.56,75.0,668.8,0.055,1.18,41.69,0,1,1,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,43.0,59.7,59.5,7,7,5,Disability,0 |
| HC003-0000490,1.41,Male,Asian,US,Middle,A,Mild,19.53,Large_deletion,1,0,None_on_demand,Plasma_derived,10.0,3x_week,19.5,10.8,0.844,184325,195142,0,1,23.5,1,Monthly,0.886,0,1,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,19,7.3,16.9,Severe,33.6,1.0,0,1,31.9,0,0,20.8,108.4,145.0,0,N/A,0,69.8,115.5,2.63,87.2,865.3,0.184,1.75,6.11,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,51.8,69.8,69.0,1,12,5,Unemployed,0 |
| HC003-0000491,1.23,Male,Hispanic,US,Low,A,Mild,39.63,Intron22_inversion,1,0,None_on_demand,Recombinant_SHL,10.0,Every_other_day,13.6,8.0,0.676,626613,142717,0,0,11.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,14,10,0,0,0,0,0,0,11,12.0,9.7,Moderate,8.9,5.4,0,1,18.3,0,0,45.1,96.9,145.0,0,N/A,0,76.9,88.2,2.49,101.5,581.7,0.48,1.05,3.8,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,4,42.5,57.9,82.7,4,10,11,Unemployed,2 |
| HC003-0000492,2.55,Female,White_non_Hispanic,Asia_Pacific,High,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_EHL,38.2,Every_other_day,10.6,25.0,0.664,379913,752482,1,0,28.8,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,1,23,3.4,0.0,None,0.5,15.2,1,0,41.1,0,0,34.1,140.0,139.3,0,N/A,0,97.2,116.2,2.3,112.7,526.3,0.382,7.31,10.87,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,1,16,40.6,50.8,87.2,0,7,5,Employed_full,0 |
| HC003-0000493,2.07,Male,Hispanic,Europe,Middle,A,Mild,7.28,Intron22_inversion,1,0,None_on_demand,Plasma_derived,37.8,Every_other_day,12.1,8.0,0.401,154574,194447,1,0,22.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,23,17,0,0,0,0,0,0,10,0.0,21.4,Moderate,7.0,0.1,1,0,46.3,1,0,35.4,140.0,134.9,1,37.0,0,42.8,61.5,2.58,87.1,486.2,0.685,6.16,2.05,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,33.0,66.4,76.7,12,5,14,Unemployed,0 |
| HC003-0000494,4.58,Male,Hispanic,Asia_Pacific,Low,B,Severe,0.1,Missense,0,1,Secondary,Recombinant_SHL,43.1,Weekly_EHL,1.0,8.9,0.645,128779,133493,0,0,1.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,1,2,0,0,0,0,7,2.5,8.4,Mild,12.4,7.0,0,1,52.3,1,0,47.5,140.0,136.3,0,N/A,0,76.8,115.4,1.0,64.2,588.0,0.405,2.44,2.29,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,33.7,48.9,63.1,15,15,27,Employed_part,0 |
| HC003-0000495,0.38,Male,Other,Europe,Middle,A,Moderate,4.08,Intron22_inversion,1,0,None_on_demand,Recombinant_EHL,27.9,Weekly_EHL,10.9,14.1,0.433,537617,90296,0,0,21.2,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,29,22,0,0,0,0,0,0,15,14.4,28.5,Severe,48.0,9.7,0,0,40.8,0,0,62.4,117.4,123.7,0,N/A,1,57.3,41.2,2.91,112.0,1111.5,0.218,1.5,23.96,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,1,Surgical_complication,0,0,34.2,47.8,73.2,11,0,4,Employed_full,2 |
| HC003-0000496,2.07,Male,White_non_Hispanic,Other,High,A,Severe,0.1,Intron22_inversion,1,1,Tertiary,Recombinant_EHL,17.7,3x_week,7.5,16.7,0.827,271054,345485,1,0,20.5,1,Biweekly,0.886,0,0,0,1,18.2,High_titer,34,1,1,High_dose,1,14,Emicizumab_bypass,0,3,2,0,0,0,0,0,0,4,13.2,10.9,Mild,9.3,3.7,1,1,18.2,0,1,39.2,121.9,103.3,0,N/A,0,69.2,125.9,1.76,126.6,718.8,0.198,11.39,12.36,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,42.5,55.6,33.7,3,5,3,Employed_full,0 |
| HC003-0000497,0.86,Male,White_non_Hispanic,Latin_America,High,A,Mild,37.62,Small_indel,0,0,None_on_demand,Recombinant_SHL,24.6,Every_other_day,17.5,15.9,0.721,105933,150992,0,0,22.4,1,Monthly,0.99,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,3,2,0,0,0,0,0,0,24,21.6,13.1,None,43.3,9.5,1,1,25.5,1,0,65.0,140.0,99.4,1,25.0,1,41.4,99.0,2.04,75.6,757.7,0.427,6.37,3.41,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,34.7,52.7,70.5,3,0,18,Employed_part,1 |
| HC003-0000498,1.43,Male,Black_non_Hispanic,US,Middle,A,Mild,22.56,Large_deletion,1,1,Tertiary,Recombinant_SHL,28.1,Every_other_day,18.0,15.3,0.676,92054,121094,0,0,24.9,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,2,2,0,0,0,0,0,0,11,25.1,8.5,None,36.1,8.1,0,1,23.3,1,0,28.8,110.2,145.0,0,N/A,0,64.7,112.4,1.7,55.7,649.9,0.089,2.73,124.16,0,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,19.9,56.2,67.5,11,6,4,Unemployed,1 |
| HC003-0000499,8.29,Male,White_non_Hispanic,Asia_Pacific,Low,A,Moderate,3.9,Intron22_inversion,1,1,Tertiary,Non_factor,19.9,Every_other_day,15.5,12.6,0.515,137362,212809,1,0,36.0,0,N/A,0.0,0,0,0,0,0.0,None,0,1,0,N/A,0,0,N/A,0,0,0,0,0,0,0,0,0,10,9.6,13.9,Severe,22.0,11.2,0,0,50.5,1,0,56.8,125.8,124.4,0,N/A,0,72.0,106.6,2.03,77.1,674.7,0.024,11.58,2.13,1,1,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,48.8,49.3,40.4,4,7,7,Employed_full,1 |
| HC003-0000500,1.08,Male,Black_non_Hispanic,Europe,High,A,Moderate,1.1,Other,0,0,None_on_demand,Recombinant_SHL,41.2,3x_week,14.4,8.0,0.797,127556,248913,0,0,23.0,0,N/A,0.0,0,0,0,0,0.0,None,0,0,0,N/A,0,0,N/A,0,20,15,0,0,0,0,0,0,6,0.0,39.8,Severe,21.0,19.1,0,0,32.1,1,0,47.2,119.5,133.6,0,N/A,0,43.7,52.2,2.23,87.7,791.6,0.412,5.0,12.91,0,0,0,0,N/A,N/A,N/A,N/A,N/A,N/A,0,0,0,0,0,N/A,0,N/A,0,0,45.7,67.2,53.9,3,3,7,Disability,1 |
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