This is Omwaprin-a protein, from Inland taipan, contains 50 amino acids, is soluble, locates in Extracellular.

Damages membranes of susceptible bacteria (PubMed:17044815), Has antibacterial activity against the Gram-positive bacteria B,megaterium and S,warneri (PubMed:17044815, PubMed:20669184), After a 45-minute treatment with this protein, B,megaterium have no visible pili and are smooth (PubMed:20669184), Has no antibacterial activity against the Gram-positive bacteria B,thuringiensis, S,aureus, S,clavuligerus and B, anthracis, or the Gram-negative bacteria E,coli and A,tumefaciens (PubMed:17044815, PubMed:20669184), Has no hemolytic activity (PubMed:17044815), Does not inhibit the proteinases elastase and cathepsin G (PubMed:17044815), Is not toxic to mice (PubMed:17044815)


This is U19-ctenitoxin-Pn1a protein, from Brazilian armed spider, contains 68 amino acids, is soluble, locates in Extracellular.


This is U11-ctenitoxin-Pn1b protein, from Brazilian armed spider, contains 58 amino acids, is soluble, locates in Extracellular.

Belongs to the neurotoxin 09 (Tx3-6) family


This is U7-ctenitoxin-Pk1a protein, from Brazilian wandering spider, contains 54 amino acids, is soluble, locates in Extracellular.

Blocks voltage-gated sodium channels (Nav), Causes immediate spastic paralysis and death in mice within 1 min of injection at dose levels of 1,5 ug per mouse

Belongs to the neurotoxin 03 (Tx2) family, 04 subfamily


This is Omega-ctenitoxin-Pr2a protein, from Brazilian Amazonian armed spider, contains 55 amino acids, is soluble, locates in Extracellular.

Antagonist of L-type calcium channels (Cav1/CACNA1), In vivo, causes paralysis in posterior limbs, and gradual decrease in movement and aggression during 24 hours after intracerebroventricular injection in mice at dose levels of 3 ug per mouse


This is U7-ctenitoxin-Pr1a protein, from Brazilian Amazonian armed spider, contains 58 amino acids, is soluble, locates in Extracellular.


This is U24-ctenitoxin-Pn1a protein, from Brazilian armed spider, contains 128 amino acids, is soluble, locates in Extracellular.


This is U5-ctenitoxin-Pk1a protein, from Brazilian wandering spider, contains 78 amino acids, is soluble, locates in Extracellular.

Lethal neurotoxin, Causes spastic paralysis and death in mice in 4-6 min after intracerebroventricular injection at dose levels of 1,5 ug per mouse

Belongs to the neurotoxin 04 (omega-agtx) family, 02 (Tx1) subfamily


This is Actin, cytoplasmic A4 protein, from Silk moth, contains 376 amino acids, is soluble, locates in Cytoplasm.

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells, Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction


This is Conotoxin Rg11a protein, from Crown cone, contains 44 amino acids, is soluble, locates in Extracellular.

Neurotoxin, Elicits hypersensibility when injected intracranially in mice, May act via potassium channel currents


This is Palustrin-3b protein, from Pickerel frog, contains 48 amino acids, is soluble, locates in Extracellular.

Antimicrobial activity against Gram-negative bacterium E,coli

Belongs to the frog skin active peptide (FSAP) family, Brevinin subfamily


This is Palustrin-3a protein, from Pickerel frog, contains 48 amino acids, is soluble, locates in Extracellular.


This is Beta-mammal toxin Tpa2 protein, from Colombian scorpion, contains 65 amino acids, is soluble, locates in Extracellular.

Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing, This toxin is lethal to mice

Belongs to the long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family


This is Toxin To6 protein, from Amazonian scorpion, contains 85 amino acids, is soluble, locates in Extracellular.

Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing

Belongs to the long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family, Beta subfamily


This is Toxin To7 protein, from Amazonian scorpion, contains 84 amino acids, is soluble, locates in Extracellular.

Inhibits voltage-gated sodium channels (Nav)


This is Omega-oxotoxin-Ol1b protein, from Lynx spider, contains 55 amino acids, is soluble, locates in Extracellular.

Weak blocker of vertebrate P/Q-, N- and L-type voltage-gated calcium channels (Cav1 and Cav2) (By similarity), Is both paralytic and lethal when injected into lepidopteran larvae, Is not toxic to mice

Belongs to the spiderine family, Spiderine subfamily


This is Pelovaterin protein, from Chinese softshell turtle, contains 42 amino acids, is soluble, locates in Extracellular.

Induces the nucleation and stabilization of vaterite, one of the crystalline polymorphs of calcium carbonate, Exhibits strong antimicrobial activity against Pseudomonas aeruginosa and Proteus vulgaris


This is Esculentin-1 protein, from Sahara frog, contains 46 amino acids, is soluble, locates in Extracellular.

Antimicrobial peptide (By similarity), Stimulates insulin release by BRIN-BD11 cells in vitro

Belongs to the frog skin active peptide (FSAP) family, Esculentin subfamily


This is Esculentin-1B protein, from Sahara frog, contains 46 amino acids, is soluble, locates in Extracellular.

Antimicrobial peptide (By similarity), Stimulates insulin secretion by BRIN-BD11 cells in vitro (PubMed:16394170)


This is C-type Lectin CRL protein, from Red diamond rattlesnake, contains 135 amino acids, is soluble, locates in Extracellular.

Beta-galactoside and N-acetylgalactosamine (GalNAc) specific C-type lectin


This is Alpha-bungarotoxin N3 protein, from Malayan krait, contains 73 amino acids, is soluble, locates in Extracellular.

Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission (By similarity), Mice injected with this toxin develop flaccid paralysis followed by death, Irreversibly inhibits twitches in a concentration-dependent manner in rat phrenic nerve-hemidiaphragm and chick biventer cervicis muscle (PubMed:19728988)

Belongs to the snake three-finger toxin family, Long-chain subfamily, Type II alpha-neurotoxin sub-subfamily


This is Proline-rich antimicrobial peptide 2 protein, from Greater wax moth, contains 42 amino acids, is soluble, locates in Extracellular.

Antimicrobial protein, Has antibacterial activity against the Gram-positive bacterium M,luteus (MIC=8,6 uM), Lacks antibacterial activity against the Gram-positive bacteria B,circulans, L,monocytogenes, S,aureus, and S,lutea, and the Gram-negative bacteria E,coli D31, E,coli ATCC 25922, and S,typhimurium, Lacks antifungal activity against S,cerevisiae, P,pastoris, Z,marxianus, C,albicans, C,fructus, C,wickerhamii, A,niger, F,oxysporum, and T,harizianum


This is Anionic antimicrobial peptide 2 protein, from Greater wax moth, contains 60 amino acids, is soluble, locates in Extracellular.

Antimicrobial protein, Has antibacterial activity against the Gram-positive bacteria M,luteus (MIC=86,6 uM), L,monocytogenes (MIC=86,6 uM), and S,lutea (MIC=86,6 uM), Lacks antibacterial activity against the Gram-positive bacteria B,circulans and S,aureus, and the Gram-negative bacteria E,coli D31, E,coli ATCC 25922, and S,typhimurium, Has antifungal activity against P,pastoris (MIC=86,6 uM) and P,stipitis (MIC=90,9 uM), but lacks antifungal activity against A,niger, C,albicans, C,albidus, C,fructus, C,wickerhamii, F,oxysporum, S,cerevisiae, S,pombe, T,harzianum, and Z,marxianus


This is M-zodatoxin-Lt8b protein, from Spider, contains 129 amino acids, is soluble, locates in Extracellular.

Insecticidal, cytolytic and antimicrobial peptide, Forms voltage-dependent, ion-permeable channels in membranes, At high concentration causes cell membrane lysis (By similarity)

Belongs to the cationic peptide 06 (cytoinsectotoxin) family


This is M-zodatoxin-Lt8c protein, from Spider, contains 129 amino acids, is soluble, locates in Extracellular.


This is M-zodatoxin-Lt8d protein, from Spider, contains 129 amino acids, is soluble, locates in Extracellular.


This is M-zodatoxin-Lt8e protein, from Spider, contains 129 amino acids, is soluble, locates in Extracellular.


This is Mu-thomitoxin-Hme1b protein, from Crab spider, contains 40 amino acids, is soluble, locates in Extracellular.

Blocks the Nav1,2/SCN2A, Nav1,4/SCN4A, Nav1,5/SCN5A and Nav1,6/SCN8A sodium channels, Shows a slight preference for the Nav1,2 and Nav1,4 channels, Reduces the peak amplitude of the sodium current and negatively shifts the steady-state inactivation process, Does not shift the threshold potential of activation or the voltage corresponding to maximal current, Does not change the reversal potential of the sodium current, May act on site 1 of the receptor

Belongs to the neurotoxin 19 (CSTX) family


This is Alpha-centractin protein, from Rat, contains 376 amino acids, is soluble, locates in Cytoplasm.

Part of the ACTR1A/ACTB filament around which the dynactin complex is built, The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules

Belongs to the actin family, ARP1 subfamily


This is Oxiana weak toxin protein, from Central Asian cobra, contains 65 amino acids, is soluble, locates in Extracellular.

Binds to muscle and neuronal nicotinic acetylcholine receptors (nAChR) (Ref,1), It binds to extracellular domain of rat alpha-7/CHRNA7 nAChR (IC(50)=2,2 uM) and to Torpedo californica membranes (IC(50)=30 uM) (Ref,1)

Belongs to the snake three-finger toxin family, Ancestral subfamily, Orphan group II sub-subfamily


This is Phylloseptin-Az3 protein, from Orange-legged monkey tree frog, contains 66 amino acids, is soluble, locates in Extracellular.

Belongs to the frog skin active peptide (FSAP) family, Phylloseptin subfamily


This is 6-phosphogluconolactonase protein, from Rat, contains 257 amino acids, is soluble, locates in Cytoplasm.

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate

Belongs to the glucosamine/galactosamine-6-phosphate isomerase family, 6-phosphogluconolactonase subfamily


This is Short neurotoxin MS11 protein, from Surinam coral snake, contains 58 amino acids, is soluble, locates in Extracellular.

Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site, Binds to and inhibits the endogenous nicotinic acetylcholine receptors (nAChR) in the human rhabdomyosarcoma TE 671 cell line with an IC(50) of 266 mM, Not toxic to mice by intraperitoneal injection or to zebrafish by injection at the back dorsolateral region

Belongs to the snake three-finger toxin family, Short-chain subfamily


This is Three-finger toxin MS1 protein, from Surinam coral snake, contains 59 amino acids, is soluble, locates in Extracellular.

Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site, Binds to and inhibits the endogenous nicotinic acetylcholine receptors (nAChR) in human rhabdomyosarcoma TE 671 cell line with an IC(50) of 48,2 mM, This neurotoxin is lethal to mice by intraperitoneal injection and to zebrafish by injection at the back of the dorsolateral region

Belongs to the snake three-finger toxin family, Short-chain subfamily, Type I alpha-neurotoxin sub-subfamily


This is Long neurotoxin MS2 protein, from Surinam coral snake, contains 64 amino acids, is soluble, locates in Extracellular.

Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site, Very weak inhibitor of the endogenous nicotinic acetylcholine receptors (nAChR) in the human rhabdomyosarcoma TE 671 cell line, Not toxic to mice by intraperitoneal injection or to zebrafish by injection at the back of the dorsolateral region

Belongs to the snake three-finger toxin family, Ancestral subfamily


This is Three-finger toxin MS3 protein, from Surinam coral snake, contains 60 amino acids, is soluble, locates in Extracellular.

Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site, Binds to and inhibits the endogenous nicotinic acetylcholine receptors (nAChR) in human rhabdomyosarcoma TE 671 cell line with an IC(50) of 346 mM, This neurotoxin is lethal to mice by intraperitoneal injection and to zebrafish by injection at the back of the dorsolateral region


This is Long neurotoxin MS4 protein, from Surinam coral snake, contains 64 amino acids, is soluble, locates in Extracellular.

Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site, Weak inhibitor of the endogenous nicotinic acetylcholine receptors (nAChR) in the human rhabdomyosarcoma TE 671 cell line with an IC(50) of 690 mM, This neurotoxin is lethal to zebrafish by injection at the back of the dorsolateral region, but is not toxic to mice by intraperitoneal injection


This is Long neurotoxin MS5 protein, from Surinam coral snake, contains 64 amino acids, is soluble, locates in Extracellular.

Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site, Very weak inhibitor of the endogenous nicotinic acetylcholine receptors (nAChR) in the human rhabdomyosarcoma TE 671 cell line, This neurotoxin is lethal to zebrafish by injection at the back of the dorsolateral region, but is not toxic to mice by intraperitoneal injection


This is Actin-like protein 6B protein, from Rat, contains 426 amino acids, locates in Nucleus.

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology), Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner, Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth, During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state, The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes, As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF), The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells, The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth, ACTL6B/BAF53B is not essential for assembly of the nBAF complex but is required for targeting the complex and CREST to the promoter of genes essential for dendritic growth, Essential for neuronal maturation and dendrite development (By similarity)


This is Basic phospholipase A2 3 protein, from Russel's viper, contains 121 amino acids, is soluble, locates in Extracellular.

PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides

Belongs to the phospholipase A2 family, Group II subfamily, D49 sub-subfamily


This is Meucin-49 protein, from Lesser Asian scorpion, contains 75 amino acids, is soluble, locates in Extracellular.

Belongs to the non-disulfide-bridged peptide (NDBP) superfamily, Long chain multifunctional peptide (group 2) family


This is Frontoxin II protein, from Coral snake, contains 59 amino acids, is soluble, locates in Extracellular.

Neurotoxin, Blocks muscular nicotinic acetylcholine receptors (nAChR)


This is Frontoxin III protein, from Coral snake, contains 62 amino acids, is soluble, locates in Extracellular.

Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission


This is Frontoxin IV protein, from Coral snake, contains 64 amino acids, is soluble, locates in Extracellular.

Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site, Binds to the muscular nicotinic acetylcholine receptor (nAChR)


This is Frontoxin V protein, from Coral snake, contains 64 amino acids, is soluble, locates in Extracellular.


This is Vacuolar fusion protein CCZ1 homolog B protein, from Human, contains 482 amino acids, is membrane-bound, locates in Lysosome/Vacuole.


This is Lactose-binding lectin-2 protein, from Dioclea purpurea, contains 239 amino acids, locates in Lysosome/Vacuole.

Lactose-binding lectin, Also binds derivatives of galactose, glucose, lactose, and mannose, Binds O-glycoproteins such as mucins more strongly than N-glycoproteins, Shows agglutinating activity towards rabbit erythrocytes


This is Venom allergen 5 protein, from Hornet, contains 225 amino acids, is soluble, locates in Extracellular.

Belongs to the CRISP family, Venom allergen 5-like subfamily


This is Hyaluronidase protein, from Hornet, contains 357 amino acids, is soluble, locates in Extracellular.

Hydrolyzes high molecular weight hyaluronic acid to produce small oligosaccharides

Belongs to the glycosyl hydrolase 56 family


This is Antimicrobial peptide lumbricin-PG protein, from Earthworm, contains 73 amino acids, is soluble, locates in Extracellular.

Displays antimicrobial activity against the Gram-positive bacterium S,aureus ATCC 2592, the Gram-negative bacteria E,coli ATCC 25922 and P,aeruginosa ATCC 27853, and the fungus C,albicans ATCC 2002, Displays stronger activity against P,aeruginosa and S,aureus than E,coli, Displays very weak hemolytic activity


This is Putative chitinase protein, from Silver-lipped pearl oyster, contains 466 amino acids, is soluble, locates in Extracellular.

Belongs to the glycosyl hydrolase 18 family


This is Basic phospholipase A2 protein, from Whitetail lancehead, contains 122 amino acids, is soluble, locates in Extracellular.

Snake venom phospholipase A2 (PLA2) that does not inhibit platelet aggregation, Exhibits cytotoxic and anticoagulant activity, Induces Ehrlich tumor growth but not angiogenesis, PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides


This is Basic phospholipase A2 homolog blK-PLA2 protein, from Whitetail lancehead, contains 121 amino acids, is soluble, locates in Extracellular.

Snake venom phospholipase A2 (PLA2) homolog that lacks enzymatic activity (By similarity), Shows myotoxic and edema-inducing activities in vivo (By similarity), A model of myotoxic mechanism has been proposed: an apo Lys49-PLA2 is activated by the entrance of a hydrophobic molecule (e,g, fatty acid) at the hydrophobic channel of the protein leading to a reorientation of a monomer (By similarity), This reorientation causes a transition between 'inactive' to 'active' states, causing alignment of C-terminal and membrane-docking sites (MDoS) side-by-side and putting the membrane-disruption sites (MDiS) in the same plane, exposed to solvent and in a symmetric position for both monomers (By similarity), The MDoS region stabilizes the toxin on membrane by the interaction of charged residues with phospholipid head groups (By similarity), Subsequently, the MDiS region destabilizes the membrane with penetration of hydrophobic residues (By similarity), This insertion causes a disorganization of the membrane, allowing an uncontrolled influx of ions (i,e, calcium and sodium), and eventually triggering irreversible intracellular alterations and cell death (By similarity)

Belongs to the phospholipase A2 family, Group II subfamily, K49 sub-subfamily


This is Probable endo-1,4-beta-xylanase B protein, from Yellow koji mold, contains 221 amino acids, is soluble, locates in Extracellular.

Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose

Belongs to the glycosyl hydrolase 11 (cellulase G) family


This is Probable phospholipase C20G8.02, mitochondrial protein, from Fission yeast, contains 757 amino acids, locates in Mitochondrion.

Probable phospholipase that hydrolyzes phosphatidic acid


This is Protein GMH1 homolog protein, from Fission yeast, contains 235 amino acids, is membrane-bound, locates in Endoplasmic reticulum.


This is Meiotically up-regulated gene 154 protein protein, from Fission yeast, contains 316 amino acids, is membrane-bound, locates in Endoplasmic reticulum.


This is DnaJ homolog 1, mitochondrial protein, from Fission yeast, contains 528 amino acids, has 1 CR-type Zinc finger, locates in Mitochondrion.

CR-type


This is Protein lsb5 protein, from Fission yeast, contains 304 amino acids, is soluble, locates in Cytoplasm.

Essential for the organization of the actin cytoskeleton, fluid phase endocytosis and vesicle trafficking


This is Translation machinery-associated protein 20 protein, from Baker's yeast, contains 181 amino acids, is soluble, locates in Cytoplasm.


This is RNA polymerase II-associated factor 1 homolog protein, from Caenorhabditis elegans, contains 425 amino acids, locates in Nucleus.

Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification


This is Leucine-rich repeat-containing protein egg-6 protein, from Caenorhabditis elegans, contains 961 amino acids, is membrane-bound, locates in Cell membrane.

Required for apical extracellular matrix organization and epithelial junction maintenance


This is Cathepsin B-like CP1 protein, from Giardia lamblia, contains 303 amino acids, locates in Lysosome/Vacuole.

Thiol protease which is required for parasite excystation and invasion of the proximal small intestine of the human host


This is Cathepsin B-like CP2 protein, from Giardia lamblia, contains 300 amino acids, locates in Lysosome/Vacuole.


This is Cathepsin B-like CP3 protein, from Giardia lamblia, contains 299 amino acids, locates in Lysosome/Vacuole.


This is DNA-directed RNA polymerase 1, mitochondrial protein, from Mouse-ear cress, contains 976 amino acids, locates in Mitochondrion.

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

Belongs to the phage and mitochondrial RNA polymerase family


This is Chromatin structure-remodeling complex protein BSH protein, from Mouse-ear cress, contains 240 amino acids, locates in Nucleus.

Component of a multiprotein complex equivalent of the yeast SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes, It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors


This is Remorin protein, from Potato, contains 198 amino acids, is membrane-bound, locates in Cell membrane.

Binds to both simple and complex galacturonides, May be involved in cell-to-cell signaling and molecular transport


This is Serine protease inhibitor A6 protein, from African clawed frog, contains 436 amino acids, is soluble, locates in Extracellular.


This is Shikimate kinase, chloroplastic protein, from Tomato, contains 300 amino acids, locates in Plastid.

Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate


This is Heterogeneous nuclear ribonucleoprotein U-like protein 2 protein, from Mouse, contains 745 amino acids, locates in Nucleus.


This is Clock-controlled pheromone ccg-4 protein, from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), contains 299 amino acids, is soluble, locates in Extracellular.

Pheromone that is regulated by the circadian clock, Expression is mating type specific and under the control of the mating type locus, Involved in conidiation


This is Zinc finger protein 41 protein, from Mouse, contains 198 amino acids, has 4 C2H2-type Zinc finger, locates in Nucleus.

A putative DNA-binding regulatory protein associated with meiosis in spermatogenesis

Belongs to the krueppel C2H2-type zinc-finger protein family


This is Small ribosomal subunit protein bS16m protein, from Baker's yeast, contains 121 amino acids, locates in Mitochondrion.

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane

Belongs to the bacterial ribosomal protein bS16 family


This is Mitochondrial protein PET191 protein, from Baker's yeast, contains 108 amino acids, is soluble, locates in Mitochondrion.

Involved in the assembly of cytochrome c oxidase


This is Mitochondrial GTPase 1 protein, from Baker's yeast, contains 367 amino acids, is membrane-bound, locates in Mitochondrion.

Mitochondrial GTPase involved in assembly of the large ribosomal subunit (PubMed:12808030), Plays a role in expression of the mitochondrial translational machinery (PubMed:12808030)

Belongs to the TRAFAC class YlqF/YawG GTPase family, MTG1 subfamily


This is ATPase synthesis protein 25, mitochondrial protein, from Baker's yeast, contains 612 amino acids, is membrane-bound, locates in Mitochondrion.

mRNA stabilization factor specific for the 0,95 kb OLI1 mRNA, Also involved in OLI1 ring formation


This is Small ribosomal subunit protein uS10m protein, from Baker's yeast, contains 203 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uS10 family


This is U1 small nuclear ribonucleoprotein C protein, from African clawed frog, contains 159 amino acids, has 1 Matrin-type Zinc finger, locates in Nucleus.

Matrin-type

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome, SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing, The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA, Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region

Belongs to the U1 small nuclear ribonucleoprotein C family


This is Sporulation protein RMD1 protein, from Baker's yeast, contains 430 amino acids, is soluble, locates in Cytoplasm.

Required for sporulation where it is believed to have a role in meiotic nuclear division


This is Protein TMA23 protein, from Baker's yeast, contains 211 amino acids, locates in Nucleus.

Trans-acting factors of the ribosome biogenesis process


This is Suppressor of activated egl-4 protein 2 protein, from Caenorhabditis elegans, contains 305 amino acids, locates in Nucleus.

As a likely component of a histone deacetylase complex, together with saeg-1 and hda-2, functions downstream of the cAMP-dependent kinase egl-4 to regulate the expression of genes required for egg-laying and foraging (PubMed:21573134)


This is Mitochondrial intermembrane space cysteine motif-containing protein MIX17 protein, from Baker's yeast, contains 156 amino acids, is soluble, locates in Mitochondrion.


This is Pre-mRNA leakage protein 39 protein, from Baker's yeast, contains 334 amino acids, is membrane-bound, locates in Nucleus.

Involved in the nuclear retention of improperly spliced pre-mRNAs


This is Probable gluconokinase protein, from Baker's yeast, contains 193 amino acids, is soluble, locates in Cytoplasm.

Belongs to the gluconokinase GntK/GntV family


This is Altered inheritance of mitochondria protein 36, mitochondrial protein, from Baker's yeast, contains 255 amino acids, is membrane-bound, locates in Mitochondrion.


This is Small ribosomal subunit protein uS8m protein, from Baker's yeast, contains 155 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uS8 family


This is V-type ATPase assembly factor PKR1 protein, from Baker's yeast, contains 122 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Functions together with the other V-type ATPase assembly factors in the endoplasmic reticulum to efficiently assemble the V-type ATPase membrane sector V(0)


This is F-box protein YDR131C protein, from Baker's yeast, contains 556 amino acids, locates in Lysosome/Vacuole.

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, Probably recognizes and binds to phosphorylated target proteins (By similarity)


This is Small ribosomal subunit protein mS35 protein, from Baker's yeast, contains 319 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mS35 family


This is SRP-independent targeting protein 1 protein, from Baker's yeast, contains 877 amino acids, is soluble, locates in Cytoplasm.

Functions in the SND pathway, a SRP (signal recognition particle) and GET (guided entry of tail-anchored proteins) independent pathway for targeting a broad range of substrate proteins to the endoplasmic reticulum, SND functions in parallel to GET in targeting proteins with downstream hydrophobic motifs


This is Thiamine-repressible mitochondrial transport protein THI74 protein, from Baker's yeast, contains 370 amino acids, is membrane-bound, locates in Mitochondrion.

May be involved in thiaminediphosphate transport across the mitochondrial membrane


This is Protein GIS4 protein, from Baker's yeast, contains 774 amino acids, is soluble, locates in Cytoplasm.

May be involved in the Ras/cAMP signaling pathway


This is Vacuolar basic amino acid transporter 1 protein, from Baker's yeast, contains 562 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Transporter required for vacuolar uptake of at least histidine and lysine

Belongs to the major facilitator superfamily


This is Interacting with cytoskeleton protein 1 protein, from Baker's yeast, contains 127 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Required for viability of cells lacking mtDNA


This is RNA polymerase II-associated protein RBA50 protein, from Baker's yeast, contains 439 amino acids, is soluble, locates in Cytoplasm.

Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation


This is Protein HLR1 protein, from Baker's yeast, contains 423 amino acids, is soluble, locates in Cytoplasm.

Involved in cell wall composition and integrity and response to osmotic stress


This is Large ribosomal subunit protein bL34m protein, from Baker's yeast, contains 105 amino acids, locates in Mitochondrion.

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane

Belongs to the bacterial ribosomal protein bL34 family


This is Large ribosomal subunit protein uL1m protein, from Baker's yeast, contains 285 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL1 family


This is Vacuolar basic amino acid transporter 4 protein, from Baker's yeast, contains 768 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Transporter required for vacuolar uptake of basic amino acids


This is Protein ECM18 protein, from Baker's yeast, contains 453 amino acids, locates in Mitochondrion.

May be involved in cell wall organization and biogenesis

Belongs to the peptidase S33 family, ABHD4/ABHD5 subfamily


This is Golgi apparatus membrane protein TVP18 protein, from Baker's yeast, contains 167 amino acids, is membrane-bound, locates in Golgi apparatus.

Golgi membrane protein involved in vesicular trafficking


This is Family of serine hydrolases 2 protein, from Baker's yeast, contains 223 amino acids, is soluble, locates in Cytoplasm.


This is MIOREX complex component 10 protein, from Baker's yeast, contains 414 amino acids, is membrane-bound, locates in Mitochondrion.

Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression


This is Pheromone B alpha 2 receptor protein, from Split gill fungus, contains 627 amino acids, is membrane-bound, locates in Cell membrane.

Receptor for the BAP2 pheromone, a prenylated mating factor, The receptor/pheromone interaction may have a role in the fusion of clamp cells

Belongs to the G-protein coupled receptor 4 family


This is RNA-binding suppressor of PAS kinase protein 1 protein, from Baker's yeast, contains 457 amino acids, is soluble, locates in Cytoplasm.


This is Proteasome chaperone 1 protein, from Baker's yeast, contains 276 amino acids, is soluble, locates in Cytoplasm.


This is Protein CLT1, chloroplastic protein, from Mouse-ear cress, contains 447 amino acids, is membrane-bound, locates in Plastid.

Involved in thiol transport from the plastid to the cytosol, Transports probably both glutathione (GSH) and its precursor, gamma-glutamylcysteine (gamma-EC), Exhibits some functional redundancy with CLT3 in maintaining the root GSH pool

Belongs to the CRT-like transporter family


This is Zinc finger protein STP3 protein, from Baker's yeast, contains 343 amino acids, has 1 C2H2-type Zinc finger, locates in Nucleus.


This is Accumulates dyads protein 4 protein, from Baker's yeast, contains 493 amino acids, is soluble, locates in Cytoplasm.

Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation, May be required to stabilize the outer plaque of the spindle pole body (SPB)


This is Required for respiratory growth protein 8, mitochondrial protein, from Baker's yeast, contains 277 amino acids, locates in Mitochondrion.

Required for respiratory activity and maintenance and expression of the mitochondrial genome


This is Sporulation-specific protein 77 protein, from Baker's yeast, contains 477 amino acids, is soluble, locates in Cytoplasm.

Required for spore wall assembly and ascus formation


This is WD repeat-containing protein JIP5 protein, from Baker's yeast, contains 492 amino acids, locates in Nucleus.


This is Curing of [URE3] protein 1 protein, from Baker's yeast, contains 252 amino acids, locates in Nucleus.

Involved in the curing of prion [URE3], Nuclear localization of this protein may suggest a role in transcription regulation, so it might exert an effect on [URE3] through known prion-curing chaperones or BTN2


This is Protein SYM1 protein, from Baker's yeast, contains 197 amino acids, is membrane-bound, locates in Mitochondrion.

May be involved in cellular response to stress, Required to maintain mitochondrial DNA (mtDNA) integrity and stability, Required for ethanol metabolism and tolerance during heat shock

Belongs to the peroxisomal membrane protein PXMP2/4 family


This is Glycosylphosphatidylinositol anchor biosynthesis protein 11 protein, from Baker's yeast, contains 219 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Acts in the GPI biosynthetic pathway between GlcNAc-PI synthesis and GPI transfer to protein, Required for the formation of complete GPI precursors CP1 and CP2


This is DNA repair protein RAD34 protein, from Baker's yeast, contains 692 amino acids, locates in Nucleus.

Involved in nucleotide excision repair (NER) of damaged ribosomal DNA (rDNA), Required for the repair of the RNA polymerase I-transcribed strand of rDNA


This is MIOREX complex component 9 protein, from Baker's yeast, contains 420 amino acids, is membrane-bound, locates in Mitochondrion.


This is Extracellular superoxide dismutase [Cu-Zn] protein, from Onchocerca volvulus, contains 201 amino acids, is soluble, locates in Extracellular.

Destroys radicals which are normally produced within the cells and which are toxic to biological systems, May act in the parasite defense against phagocyte-generated reactive oxygen species

Belongs to the Cu-Zn superoxide dismutase family


This is Endoplasmic reticulum transmembrane protein 3 protein, from Baker's yeast, contains 203 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi, May be involved in invertase secretion


This is Protein WHI4 protein, from Baker's yeast, contains 649 amino acids, is soluble, locates in Cytoplasm.

Has a partially redundant function to WHI3, a dosage-dependent modulator of cell size


This is Morphogenetic regulator of filamentous growth protein 1 protein, from Baker's yeast, contains 458 amino acids, locates in Nucleus.

Transcriptional regulator with a general role in all morphogenetically distinct forms of filamentous growth, namely haploid invasive growth, biofilm formation, and diploid pseudohyphal growth, May control FLO11 gene expression as part of a promoter-bound complex with FLO8 and MSS1


This is Protein CMS1 protein, from Baker's yeast, contains 291 amino acids, locates in Nucleus.

May play a role in the regulation of DNA replication and cell cycle control


This is 58 kDa phosphoprotein protein, from Plasmodium berghei, contains 423 amino acids, is soluble, locates in Cytoplasm.

May play a role in protein folding or protein-protein interactions, May act as a co-chaperone


This is AP-1-like transcription factor YAP7 protein, from Baker's yeast, contains 245 amino acids, locates in Nucleus.

Probable transcription activator linked to cell cycle that induces transcription activation of genes in the environmental stress response and metabolism control pathways, like the closely related YAP5

Belongs to the bZIP family, YAP subfamily


This is Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP54 protein, from Baker's yeast, contains 384 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Regulates the phosphatidylinositol (4,5)-diphosphate levels on the cytoplasmic surface of the endoplasmic reticulum and thereby regulates secretion, Does not utilize phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), nor phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 4-phosphate (PtdIns(4)P)

Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family


This is Increased recombination centers protein 23 protein, from Baker's yeast, contains 157 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Is probably involved in a pathway contributing to genomic integrity


This is Enhancer of translation termination 1 protein, from Baker's yeast, contains 412 amino acids, locates in Nucleus.

Required for correct translation termination and probably involved in regulation of hypoxic gene expression in association TPA1, Inhibits replication of Brome mosaic virus


This is AN1-type zinc finger protein TMC1 protein, from Baker's yeast, contains 150 amino acids, has 1 AN1-type Zinc finger, locates in Nucleus.

May have a role in protecting cells from metalloid-induced proteotoxicity


This is Transcriptional repressor CTCF protein, from Chicken, contains 728 amino acids, has 10 C2H2-type Zinc finger, has 1 C2H2-type 11; atypical Zinc finger, locates in Nucleus.

C2H2-type 11; atypical

Acts as both a transcriptional activator and repressor of the MYC gene

Belongs to the CTCF zinc-finger protein family


This is Meiotic sister-chromatid recombination protein 6, mitochondrial protein, from Baker's yeast, contains 692 amino acids, locates in Mitochondrion.

May be involved in the control of meiotic sister-chromatid recombination


This is Oxidation resistance protein 1 protein, from Baker's yeast, contains 273 amino acids, locates in Mitochondrion.

Involved in protection from oxidative damage


This is Mitochondrial metal transporter 2 protein, from Baker's yeast, contains 484 amino acids, is membrane-bound, locates in Mitochondrion.

Mitochondrial metal transporter involved in mitochondrial iron accumulation

Belongs to the cation diffusion facilitator (CDF) transporter (TC 2,A,4) family, SLC30A subfamily


This is Coilin protein, from African clawed frog, contains 536 amino acids, locates in Nucleus.


This is Meiotic recombination protein rec15 protein, from Fission yeast, contains 180 amino acids, locates in Nucleus.

Required during the early stages of meiosis for meiotic recombination


This is RNA-binding protein rnp24 protein, from Fission yeast, contains 369 amino acids, locates in Nucleus.


This is BCL7-like protein protein, from Caenorhabditis elegans, contains 146 amino acids, locates in Nucleus.

Required for the terminal differentiation of seam cells, and the differentiation of distal tip cells important for normal somatic gonad and germ cell development, Plays a role in the Wnt signaling pathway, regulating the expression of beta-catenin homologs wrm-1, bar-1 and sys-1, and the localization of wrm-1 and the wnt signaling pathway component pop-1 during asymmetric cell division of seam cells and the Z-cell lineage of the somatic gonad, respectively, May have a pro-apoptotic role, possibly linked to the negative regulation of expression of anti-apoptotic factor ced-9


This is mRNA export protein mlo3 protein, from Fission yeast, contains 199 amino acids, locates in Nucleus.

Has a role in the mRNA export process, Interferes with mitotic chromosome segregation when overexpressed


This is Probable splicing factor, arginine/serine-rich 4 protein, from Caenorhabditis elegans, contains 196 amino acids, locates in Nucleus.

May play a functionally redundant role in embryogenesis

Belongs to the splicing factor SR family


This is Growth arrest-specific protein 1 homolog protein, from Caenorhabditis elegans, contains 228 amino acids, is membrane-bound, locates in Cell membrane.


This is ATPase synthesis protein 25, mitochondrial protein, from Fission yeast, contains 542 amino acids, is membrane-bound, locates in Mitochondrion.

mRNA stabilization factor specific for the 0,95 kb oli1 mRNA, Also involved in oli1 ring formation (By similarity)


This is Uncharacterized membrane protein C24H6.13 protein, from Fission yeast, contains 871 amino acids, is membrane-bound, locates in Golgi apparatus.

Acts as an osmosensitive calcium-permeable cation channel


This is Importin beta-like protein kap111 protein, from Fission yeast, contains 990 amino acids, locates in Nucleus.

Functions as a component of the nuclear pore complex (NPC), NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors, Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope


This is Autophagy-related protein 22 protein, from Fission yeast, contains 529 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation, The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation


This is Probable protein transport protein Sec61 subunit gamma protein, from Fission yeast, contains 70 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Necessary for protein translocation in the endoplasmic reticulum


This is Snaclec subunit B protein, from Green snake, contains 156 amino acids, is soluble, locates in Extracellular.

Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example)


This is Cell cycle regulator of non-homologous end joining protein, from Chinese hamster, contains 154 amino acids, is soluble, locates in Cytoplasm.

Cell-cycle-specific regulator of classical non-homologous end joining (NHEJ) of DNA double-strand break (DSB) repair, which can act both as an activator or inhibitor of NHEJ, depending on the cell cycle phase (By similarity), Acts as a regulator of DNA repair pathway choice by specifically inhibiting classical NHEJ during the S and G2 phases, thereby promoting error-free repair by homologous recombination during cell cycle phases when sister chromatids are present, Preferentially protects single-stranded overhangs at break sites by inhibiting classical NHEJ, thereby creating a local environment that favors homologous recombination, Acts via interaction with XRCC5/Ku80 and XRCC6/Ku70 (By similarity), In contrast, acts as an activator of NHEJ during G1 phase of the cell cycle: promotes classical NHEJ in G1 phase cells via multivalent interactions that increase the affinity of DNA damage response proteins for DSB-associated chromatin, Also involved in immunoglobulin V(D)J recombination (By similarity), May act as a regulator of proteasome (PubMed:17043244), In case of infection by a retrovirus, may regulate the proteasome during the uncoating phase of retrovirus (PubMed:17043244)


This is Big defensin protein, from Bay scallop, contains 122 amino acids, is soluble, locates in Extracellular.

Significantly inhibits the growth of Gram-negative and Gram-positive bacteria and fungi in vitro


This is Dehydration-responsive element-binding protein 2A protein, from Rice, contains 274 amino acids, locates in Nucleus.

Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3' of the cis-acting dehydration-responsive element (DRE), Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription

Belongs to the AP2/ERF transcription factor family, ERF subfamily


This is Large ribosomal subunit protein uL15m protein, from Bovine, contains 297 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL15 family


This is Solute carrier family 12 member 9 protein, from African clawed frog, contains 899 amino acids, is membrane-bound, locates in Cell membrane.

Seems to correspond to a subunit of a multimeric transport system and thus, additional subunits may be required for its function

Belongs to the SLC12A transporter family


This is Tryptophyllin-T1 protein, from Orange-legged monkey tree frog, contains 61 amino acids, is soluble, locates in Extracellular.

Belongs to the frog skin active peptide (FSAP) family, Tryptophillin subfamily


This is Phylloseptin-H6 protein, from Orange-legged leaf frog, contains 66 amino acids, is soluble, locates in Extracellular.

Belongs to the frog skin active peptide (FSAP) family, Phylloseptin subfamily


This is Probable methyltransferase PMT25 protein, from Mouse-ear cress, contains 770 amino acids, is membrane-bound, locates in Golgi apparatus.

Belongs to the methyltransferase superfamily


This is MAM domain-containing glycosylphosphatidylinositol anchor protein 1 protein, from Chicken, contains 949 amino acids, has 6 Ig-like Immunoglobulin domain, is membrane-bound, locates in Cell membrane.

Ig-like

Ig-like

Ig-like

Ig-like

Ig-like

Ig-like

Required for radial migration of cortical neurons in the superficial layer of the neocortex


This is Endo-1,4-beta-xylanase G protein, from Verticillium wilt, contains 250 amino acids, is soluble, locates in Extracellular.

Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose, The most favorable substrate is beechwood xylan

Belongs to the glycosyl hydrolase 11 (cellulase G) family


This is Protein unc-50 protein, from Caenorhabditis elegans, contains 301 amino acids, is membrane-bound, locates in Golgi apparatus.

Required for cell surface expression of acetylcholine receptors in body-wall muscles


This is Hydrogen peroxide stress regulator 1 protein, from Fission yeast, contains 582 amino acids, has 1 C2H2-type Zinc finger, has 1 C2H2-type 2; atypical Zinc finger, locates in Nucleus.

C2H2-type 2; atypical

Transcription factor that globally supports gene expression in response to hydrogen peroxide


This is Probable glutathione-independent glyoxalase hsp3104 protein, from Fission yeast, contains 222 amino acids, is soluble, locates in Cytoplasm.

Catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step, May play a role in detoxifying endogenously produced glyoxals, Involved in protection against reactive oxygen species (ROS)

Belongs to the peptidase C56 family, HSP31-like subfamily


This is Uncharacterized protein C17D1.07c protein, from Fission yeast, contains 949 amino acids, locates in Nucleus.


This is mRNA cleavage and polyadenylation specificity factor complex subunit pta1 protein, from Fission yeast, contains 670 amino acids, locates in Nucleus.

Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB


This is 25S rRNA (adenine(645)-N(1))-methyltransferase protein, from Fission yeast, contains 318 amino acids, locates in Nucleus.

S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25,1 in 25S rRNA, Required both for ribosomal 40S and 60S subunits biogenesis, Required for efficient pre-rRNA cleavage at site A2 (By similarity)

Belongs to the methyltransferase superfamily, RRP8 family


This is Signal peptidase complex subunit 3 protein, from Fission yeast, contains 185 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Essential component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum, Essential for the SPC catalytic activity, possibly by stabilizing and positioning the active center of the complex close to the lumenal surface, Essential for viability


This is Multicopy suppressor of sporulation protein msa1 protein, from Fission yeast, contains 533 amino acids, is soluble, locates in Cytoplasm.

Negative regulator of sexual differentiation, Acts by repressing the transcription of meiosis-inducing, ste11-regulated genes


This is Probable citrate synthase, mitochondrial protein, from Fission yeast, contains 483 amino acids, is soluble, locates in Mitochondrion.


This is tRNA ligase 1 protein, from Fission yeast, contains 787 amino acids, is soluble, locates in Cytoplasm.

Required for the splicing of precursor tRNA molecules containing introns, The ligation activity requires three enzymatic activities: phosphorylation of the 5' terminus of the 3' half-tRNA in the presence of ATP, opening of the 2'3'-cyclic phosphodiester bond of the 5' half-tRNA leaving a 2'-phosphomonoester and ligation of the two tRNA halves in an ATP-dependent reaction


This is Mediator of RNA polymerase II transcription subunit 20 protein, from Fission yeast, contains 193 amino acids, locates in Nucleus.

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes, Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery, The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors

Belongs to the Mediator complex subunit 20 family


This is Homeobox transcription factor phx1 protein, from Fission yeast, contains 942 amino acids, locates in Nucleus.

Trnascription factor that regulates the expression of the homocitrate synthase (HCS) lys4


This is GPI transamidase component PIG-S homolog protein, from Fission yeast, contains 554 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Component of the GPI transamidase complex, Involved in transfer of GPI to proteins (By similarity)


This is ADP-ribosylation factor GTPase-activating protein glo3 protein, from Fission yeast, contains 483 amino acids, has 1 C4-type Zinc finger, locates in Golgi apparatus.

GTPase-activating protein for the ADP ribosylation factor (ARF) family, Involved in retrograde vesicular transport from the Golgi to the endoplasmic reticulum (By similarity)


This is Uncharacterized protein C22E12.19 protein, from Fission yeast, contains 661 amino acids, locates in Nucleus.


This is CWF19-like protein mug161 protein, from Fission yeast, contains 561 amino acids, locates in Nucleus.


This is Intermediate cleaving peptidase 55 protein, from Fission yeast, contains 486 amino acids, is membrane-bound, locates in Mitochondrion.

Aminopeptidase which cleaves preprotein intermediates that carry destabilizing N-ter amino acid residues after the mitochondrial processing peptidase (MPP) cleavage site and is thus critical for stabilization of the mitochondrial proteome


This is Protein kinase domain-containing protein ppk2 protein, from Fission yeast, contains 665 amino acids, is soluble, locates in Cytoplasm.


This is Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase protein, from Fission yeast, contains 501 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation, Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity)

Belongs to the ALG6/ALG8 glucosyltransferase family


This is ATPase expression protein 3 protein, from Baker's yeast, contains 606 amino acids, is membrane-bound, locates in Mitochondrion.

Required for respiration, Stabilizes the mitochondrial bicistronic mRNA encoding ATP6 and ATP8, 2 subunits of the proton-translocating ATP synthase


This is Nutrient and stress factor 1 protein, from Baker's yeast, contains 391 amino acids, has 2 C2H2-type Zinc finger, locates in Nucleus.

Transcription factor that participates in the transcriptional activation of glucose-repressed genes during exponential growth in non-fermentable carbon conditions, Also involved in salt-stress response


This is Required for respiratory growth protein 1, mitochondrial protein, from Baker's yeast, contains 365 amino acids, locates in Mitochondrion.

Essential for respiratory growth and required for mitochondrial protein synthesis, Required for vacuolar acidification


This is Transmembrane protein 115 homolog protein, from Baker's yeast, contains 342 amino acids, is membrane-bound, locates in Golgi apparatus.

May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum


This is rRNA-processing protein FYV7 protein, from Baker's yeast, contains 151 amino acids, locates in Nucleus.

Involved in the processing of the 20S pre-rRNA, Required for survival upon K1 Killer toxin exposure


This is Phosphate metabolism protein 7 protein, from Baker's yeast, contains 991 amino acids, is membrane-bound, locates in Cell membrane.

Acts as an osmosensitive calcium-permeable cation channel


This is Sterol uptake protein 2 protein, from Baker's yeast, contains 268 amino acids, locates in Nucleus.

Putative transcription factor involved in the regulation of the activity of the cAMP/protein kinase A pathway, Involved in sterol uptake


This is Protein arginine N-methyltransferase SFM1 protein, from Baker's yeast, contains 213 amino acids, is soluble, locates in Cytoplasm.

S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that monomethylates ribosomal protein S3 (RPS3) at 'Arg-146'

Belongs to the class IV-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase SFM1 family


This is 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component protein, from Baker's yeast, contains 194 amino acids, has 1 C2H2-type Zinc finger, locates in Nucleus.

Participates in pre-mRNA splicing, Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome


This is Nuclear control of ATPase protein 2 protein, from Baker's yeast, contains 616 amino acids, is membrane-bound, locates in Mitochondrion.

Involved in the mitochondrial expression of subunits 6 and 8 of the F0-F1 ATP synthase


This is Genetic interactor of prohibitin 5, mitochondrial protein, from Baker's yeast, contains 293 amino acids, locates in Mitochondrion.

Essential for respiratory growth and required for maintenance of mtDNA, Required for cell survival in the absence of prohibitins


This is Phosphatidylglycerol/phosphatidylinositol transfer protein protein, from Baker's yeast, contains 173 amino acids, locates in Lysosome/Vacuole.

Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol


This is MIOREX complex component 4 protein, from Baker's yeast, contains 430 amino acids, is membrane-bound, locates in Mitochondrion.

Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression


This is Late secretory pathway protein AVL9 protein, from Baker's yeast, contains 764 amino acids, is soluble, locates in Cytoplasm.

Functions in the late secretory pathway, Required for the generation of secretory vesicles as well as for actin polarization and polarized growth


This is Ribosomal lysine N-methyltransferase 4 protein, from Baker's yeast, contains 494 amino acids, locates in Nucleus.

S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42 (RPL42A and RPL42B) at 'Lys-55'

Belongs to the class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, SETD6 subfamily


This is Uncharacterized MFS-type transporter C330.07c protein, from Fission yeast, contains 500 amino acids, is membrane-bound, locates in Golgi apparatus.

Belongs to the major facilitator superfamily


This is Endo-1,4-beta-xylanase A protein, from Black yeast, contains 221 amino acids, is soluble, locates in Extracellular.

Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose


This is Large ribosomal subunit protein eL13A protein, from Baker's yeast, contains 199 amino acids, is soluble, locates in Cytoplasm.

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel

Belongs to the eukaryotic ribosomal protein eL13 family


This is Suppressor of presenilin protein 3 protein, from Caenorhabditis elegans, contains 684 amino acids, has 7 C2H2-type Zinc finger, locates in Nucleus.

Probable transcriptional regulator, which participates in the transcriptional repression of the presenilin protein hop-1


This is Septin and tuftelin-interacting protein 1 homolog protein, from Caenorhabditis elegans, contains 830 amino acids, locates in Nucleus.

May be involved in pre-mRNA splicing (By similarity), Required for embryonic development and survival


This is Disorganized muscle protein 1 protein, from Caenorhabditis elegans, contains 640 amino acids, has 3 Ig-like C2-type Immunoglobulin domain, is soluble, locates in Cytoplasm.

Ig-like C2-type

Ig-like C2-type

Ig-like C2-type

Stabilizes the attachment of the myofilament lattice to the muscle cell membrane, Isoform b is sufficient for wild-type function


This is Regulator of chromosome condensation protein, from Caenorhabditis elegans, contains 569 amino acids, locates in Nucleus.

Key component of the Ran GTPase system, which comprises ran-1, ran-2 and ran-3 and is essential in nucleocytoplasmic transport, Promotes the exchange of Ran-bound GDP by GTP and regulates the onset of chromosome condensation in the S phase, Binds to the chromatin, RCC1 (ran-3)/RAN (ran-1) complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA


This is Ammonium transporter Rh type C 1 protein, from Japanese pufferfish, contains 485 amino acids, is membrane-bound, locates in Cell membrane.

Functions as an ammonia transporter, May play a role in the elimination of ammonia in the gill

Belongs to the ammonium transporter (TC 2,A,49) family, Rh subfamily


This is Histone deacetylase complex subunit SAP25 protein, from Mouse, contains 186 amino acids, locates in Cytoplasm.

Involved in the transcriptional repression mediated by the mSIN3A but not the N-CoR corepressor complex


This is M-zodatoxin-Lt7a protein, from Spider, contains 97 amino acids, is soluble, locates in Extracellular.

Does not have antimicrobial or antifungal activity, Does not have hemolytic activity against rabbit erythrocytes, However, it causes some conductance changes in planar bilayer membranes, without membrane rupture, suggesting a cytolytic function on other biological targets, It causes paralysis, but is not lethal when injected into insect (M,domestica) larvae

Belongs to the cationic peptide 03 (latarcin) family, 07 subfamily


This is PRA1 family protein C protein, from Mouse-ear cress, contains 127 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments


This is Neuromedin-S protein, from Yellow-bellied toad, contains 128 amino acids, is soluble, locates in Extracellular.

Neuromedin-S-17: stimulates uterine smooth muscle contraction (B similarity), Synthetic peptide NmS-17 induces calcium mobilization in CHO cells transfected with either human FM-3/GPR66 (EC(50)=0,085 nM) or FM-4/TGR-1 (EC(50)=0,231 nM) NmU/NmS receptors


This is Cell pattern formation-associated protein asm-1 protein, from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987), contains 643 amino acids, locates in Nucleus.

Transcription factor that regulates asexual reproduction (PubMed:8913744, PubMed:25550299), Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity), Required for rapid conidial germination, normal vegetative morphology, and protoperithecium formation (PubMed:8913744)


This is Vacuolar import and degradation protein 27 protein, from Fission yeast, contains 801 amino acids, is soluble, locates in Cytoplasm.

Has a role in the negative regulation of gluconeogenesis, Required for vacuolar catabolite degradation of fructose-1,6-bisphosphatase (FBPase) (By similarity)


This is Uncharacterized protein C3B8.09 protein, from Fission yeast, contains 597 amino acids, locates in Nucleus.


This is Centromere protein R protein, from Chicken, contains 179 amino acids, locates in Nucleus.

Transcription coregulator that can have both coactivator and corepressor functions, Involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion, Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity)


This is Fatty acid-binding protein homolog 2 protein, from Caenorhabditis elegans, contains 161 amino acids, is soluble, locates in Extracellular.

May play a role in sequestering potentially toxic fatty acids and their peroxidation products, or it may be involved in the maintenance of the impermeable lipid layer of the eggshell

Belongs to the calycin superfamily, Fatty-acid binding protein (FABP) family


This is Protein let-99 protein, from Caenorhabditis elegans, contains 698 amino acids, is soluble, locates in Cytoplasm.

Required for the proper orientation of spindles after the establishment of polarity (PubMed:9477332, PubMed:14534135), May play a role in interactions between the astral microtubules and the cortical cytoskeleton (PubMed:9477332), Required for asymmetric forces on nuclei and spindles (PubMed:9477332), Acts downstream of the PAR signaling as an intermediate that transduces polarity information to the machinery that positions the mitotic spindle, possibly by regulating force generation (PubMed:12223405), Regulates gpr-1/2 asymmetric cortical localization during the first embryonic cell divisions (PubMed:14534135), Acts antagonistically to the gpr-1/2 signaling pathway (PubMed:14534135), Regulates mes-1 expression and/or localization pattern during early embryogenesis (PubMed:11003841)


This is POC1 centriolar protein homolog protein, from Tetrahymena thermophila (strain SB210), contains 634 amino acids, is soluble, locates in Cytoplasm.

Required for structural maintenance of centrioles, ciliogenesis, and cilia-based motility


This is Histone H3.4 protein, from Tetrahymena thermophila (strain SB210), contains 136 amino acids, locates in Nucleus.

Macronuclear replacement variant which replaces conventional H3 in a subset of nucleosomes, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling, Functions redundantly to H3,3, H3,4 deposition is mainly transcription-associated, DNA replication-independent, Although not essential for vegetative growth, minor H3 variants are required for producing viable conjugation progeny by affecting late developmental stages of conjugation


This is Flagellar radial spoke protein 1 protein, from Chlamydomonas smithii, contains 814 amino acids, is soluble, locates in Cytoplasm.

Flagellar radial spokes contribute to the regulation of dynein arm activity and thus the pattern of flagellar bending, They consist of a thin stalk, which is attached to the a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules


This is Flagellar radial spoke protein 5 protein, from Chlamydomonas smithii, contains 527 amino acids, is soluble, locates in Cytoplasm.

Belongs to the aldo/keto reductase family


This is Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit protein, from Pig, contains 439 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:11443278), N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER), All subunits are required for a maximal enzyme activity (By similarity), Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity)

Belongs to the DDOST 48 kDa subunit family


This is Transthyretin protein, from Eastern gray kangaroo, contains 149 amino acids, is soluble, locates in Extracellular.

Thyroid hormone-binding protein, Probably transports thyroxine from the bloodstream to the brain (By similarity)


This is Large ribosomal subunit protein bL28m protein, from Bovine, contains 256 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bL28 family


This is Small ribosomal subunit protein uS5m protein, from Bovine, contains 430 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uS5 family


This is BTB/POZ domain-containing protein 6 protein, from African clawed frog, contains 529 amino acids, is soluble, locates in Cytoplasm.

Adapter protein for the cul3 E3 ubiquitin-protein ligase complex (By similarity), Involved in late neuronal development and muscle formation (PubMed:18855900)


This is Small ribosomal subunit protein uS3m protein, from Bovine, contains 167 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uS3 family


This is Small ribosomal subunit protein mS23 protein, from Bovine, contains 190 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mS23 family


This is Two-component response regulator ORR10 protein, from Rice, contains 201 amino acids, locates in Nucleus.

Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system, Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes, Type-A response regulators seem to act as negative regulators of the cytokinin signaling

Belongs to the ARR family, Type-A subfamily


This is Large ribosomal subunit protein uL2m protein, from Bovine, contains 306 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL2 family


This is Carboxypeptidase Y homolog A protein, from Yellow koji mold, contains 542 amino acids, locates in Lysosome/Vacuole.

Vacuolar carboxypeptidase involved in degradation of small peptides, Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity)


This is Antisense of depressing factor protein 1 protein, from Baker's yeast, contains 113 amino acids, locates in Nucleus.

Transcriptional repressor which negatively regulates transcription of FYV5 by binding to the promoter on the sense strand


This is Large ribosomal subunit protein uL11m protein, from Bovine, contains 192 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL11 family


This is Large ribosomal subunit protein mL48 protein, from Bovine, contains 212 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mL48 family


This is Centromere protein U protein, from Chicken, contains 345 amino acids, locates in Nucleus.

Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation, Required for maintenance of sister chromatid adhesion during mitotic checkpoint activation


This is Serine protease inhibitor Cvsi-1 protein, from Eastern oyster, contains 90 amino acids, is soluble, locates in Extracellular.

Slow-binding inhibitor of serine proteases, The inhibitor rapidly binds to the protease forming a weak enzyme-inhibitor complex, and this is followed by a slow isomerization forming a tight-binding enzyme-inhibitor complex, Active against subtilisin A, perkinsin and trypsin with dissociation constants of 0,29 nM, 13,7 nM and 17,7 nM respectively, Not active against thermolysin, papain or pepsin, Has antiparasitic activity against the protozoan P,marinus


This is Large ribosomal subunit protein bL27m protein, from Bovine, contains 148 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bL27 family


This is Large ribosomal subunit protein uL4m protein, from Bovine, contains 294 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL4 family


This is Protein HIRA protein, from Maize, contains 964 amino acids, locates in Nucleus.

Histone chaperone involved in maintining knox genes silencing throughout leaf development


This is WUSCHEL-related homeobox 3 protein, from Rice, contains 203 amino acids, locates in Nucleus.

Transcription factor which may be involved in developmental processes, Seems to act as repressor of YAB5


This is Protein RAE1 protein, from Mouse-ear cress, contains 349 amino acids, locates in Nucleus.


This is Protein DETOXIFICATION 29 protein, from Mouse-ear cress, contains 500 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Belongs to the multi antimicrobial extrusion (MATE) (TC 2,A,66,1) family


This is Epidermis-specific secreted glycoprotein EP1 protein, from Wild carrot, contains 389 amino acids, is soluble, locates in Extracellular.

May be involved in the limitation of water flow through the outer epidermal cell wall, either by direct modification of wall structure or as a signal instructing the protoplast to restrict water transport across the cell wall


This is Protein FAR1-RELATED SEQUENCE 12 protein, from Mouse-ear cress, contains 788 amino acids, has 1 SWIM-type Zinc finger, locates in Nucleus.

SWIM-type

Putative transcription activator involved in regulating light control of development


This is Protein FAR1-RELATED SEQUENCE 2 protein, from Mouse-ear cress, contains 807 amino acids, has 1 SWIM-type Zinc finger, locates in Nucleus.

SWIM-type


This is Calcineurin B-like protein 2 protein, from Rice, contains 225 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Acts as a calcium sensor, May promote vacuolation of aleurone cells in response to signal induced by gibberellin, CBL proteins interact with CIPK serine-threonine protein kinases, Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity)

Belongs to the calcineurin regulatory subunit family


This is Large ribosomal subunit protein uL24m protein, from Bovine, contains 216 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL24 family


This is Large ribosomal subunit protein bL33m protein, from Bovine, contains 65 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bL33 family


This is Small ribosomal subunit protein mS26 protein, from Bovine, contains 205 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mS26 family


This is Large ribosomal subunit protein uL22m protein, from Bovine, contains 204 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL22 family


This is DDB1- and CUL4-associated factor 17 protein, from Mouse, contains 519 amino acids, is membrane-bound, locates in Nucleus.

May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex


This is Synapse differentiation-inducing gene protein 1-like protein, from Mouse, contains 237 amino acids, is membrane-bound, locates in Golgi apparatus.


This is UPF0764 protein C16orf89 homolog protein, from Mouse, contains 385 amino acids, is soluble, locates in Extracellular.


This is KH homology domain-containing protein 1A protein, from Mouse, contains 166 amino acids, is soluble, locates in Cytoplasm.


This is Large ribosomal subunit protein mL38 protein, from Bovine, contains 380 amino acids, locates in Mitochondrion.

Belongs to the phosphatidylethanolamine-binding protein family, Mitochondrion-specific ribosomal protein mL38 subfamily


This is Large ribosomal subunit protein uL3m protein, from Bovine, contains 348 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL3 family


This is Large ribosomal subunit protein mL63 protein, from Bovine, contains 102 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mL63 family


This is Ethylene-responsive transcription factor 5 protein, from Common tobacco, contains 291 amino acids, locates in Nucleus.

Acts as a transcriptional activator, Binds to the GCC-box pathogenesis-related promoter element, Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways mediated by ethylene, that seems to depend on a protein kinase/phosphatase cascade, and to be influenced by methyl-jasmonate

Belongs to the ethylene-response factor family, Class 3 subfamily


This is Ethylene-responsive transcription factor 2 protein, from Common tobacco, contains 233 amino acids, locates in Nucleus.

Acts as a transcriptional activator and may be involved in disease resistance pathways, Binds to the GCC-box pathogenesis-related promoter element, Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways mediated by ethylene, that seems to depend on a protein kinase cascade, and to be influenced by methyl-jasmonate

Belongs to the ethylene-response factor family, Class 1 subfamily


This is DEAD-box ATP-dependent RNA helicase 7 protein, from Spinach, contains 685 amino acids, locates in Nucleus.

Belongs to the DEAD box helicase family, DDX21/DDX50 subfamily


This is N-(5'-phosphoribosyl)anthranilate isomerase 2, chloroplastic protein, from Mouse-ear cress, contains 275 amino acids, locates in Plastid.


This is Derlin-2.2 protein, from Maize, contains 249 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins


This is Derlin-2.1 protein, from Maize, contains 249 amino acids, is membrane-bound, locates in Endoplasmic reticulum.


This is Derlin-1.2 protein, from Maize, contains 243 amino acids, is membrane-bound, locates in Endoplasmic reticulum.


This is Thioredoxin domain-containing protein protein, from East coast fever infection agent, contains 220 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Belongs to the protein disulfide isomerase family


This is Endo-1,4-beta-xylanase UM03411 protein, from Corn smut fungus, contains 344 amino acids, is soluble, locates in Extracellular.

Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose

Belongs to the glycosyl hydrolase 10 (cellulase F) family


This is Cell division cycle 20.4, cofactor of APC complex protein, from Mouse-ear cress, contains 444 amino acids, is soluble, locates in Cytoplasm.

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle

Belongs to the WD repeat CDC20/Fizzy family


This is Putative phospholipase B-like 2 protein, from Rat, contains 585 amino acids, is soluble, locates in Lysosome/Vacuole.

Belongs to the phospholipase B-like family


This is Shugoshin-1 protein, from Maize, contains 474 amino acids, locates in Nucleus.

Plays a central role in chromosome cohesion during meiosis I by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms, Required for maintenance of centromeric cohesion before prophase II and correct segregation of chromatids during meiosis II, Has apparently no function in mitosis


This is Alpha-latrotoxin-associated low molecular weight protein-2 protein, from Mediterranean black widow spider, contains 88 amino acids, is soluble, locates in Extracellular.

May increase the toxicity of alpha-latrotoxin and/or other venom components, Is non-toxic to mice and to the cockroach Periplaneta americana

Belongs to the arthropod CHH/MIH/GIH/VIH hormone family


This is Casein kinase II subunit alpha protein, from Theileria annulata, contains 348 amino acids, is soluble, locates in Cytoplasm.

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates, The alpha chain contains the catalytic site (By similarity)

Belongs to the protein kinase superfamily, Ser/Thr protein kinase family, CK2 subfamily


This is 3-ketoacyl-CoA synthase 8 protein, from Mouse-ear cress, contains 481 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Belongs to the thiolase-like superfamily, Chalcone/stilbene synthases family


This is tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial protein, from Rat, contains 414 amino acids, locates in Mitochondrion.

Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine, Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, Involved in mitochondrial genome maintenance


This is Renal cancer differentiation gene 1 protein protein, from Human, contains 113 amino acids, is soluble, locates in Cytoplasm.


This is Short neurotoxin OH-5 protein, from King cobra, contains 78 amino acids, is soluble, locates in Extracellular.

This three-finger toxin binds and inhibits the nicotinic acetylcholine receptor (nAChR)

Belongs to the snake three-finger toxin family, Short-chain subfamily


This is Short neurotoxin OH-26 protein, from King cobra, contains 78 amino acids, is soluble, locates in Extracellular.


This is Centractin protein, from Social amoeba, contains 383 amino acids, is soluble, locates in Cytoplasm.

Component of a multi-subunit complex, PPK2 (poly P kinase complex 2) involved in microtubule based vesicle motility, It is associated with the centrosome, PPK2 complex can synthesize a poly chain of hundreds of phosphate residues linked by ATP-like bonds

Belongs to the actin family, ARP1 subfamily


This is Probable serine/threonine-protein kinase ndrB protein, from Social amoeba, contains 542 amino acids, is soluble, locates in Cytoplasm.

Belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family


This is Expansin-like protein 2 protein, from Social amoeba, contains 407 amino acids, is soluble, locates in Extracellular.

Unlikely to encode with a protein with expansin activity

Belongs to the expansin family, Expansin A subfamily


This is Histone H3-like centromeric protein A protein, from African clawed frog, contains 150 amino acids, locates in Nucleus.

Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes, Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore, The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3, May serve as an epigenetic mark that propagates centromere identity through replication and cell division, Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis


This is Phylloplanin protein, from Common tobacco, contains 150 amino acids, is soluble, locates in Extracellular.

Inhibits spore germination and leaf infection by fungal pathogens


This is Rop guanine nucleotide exchange factor 14 protein, from Mouse-ear cress, contains 576 amino acids, is membrane-bound, locates in Cell membrane.

Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP


This is ATP-dependent DNA helicase-like PIF8 protein, from Trypanosoma brucei brucei (strain 927/4 GUTat10.1), contains 693 amino acids, is soluble, locates in Mitochondrion.

Required for the maintenance of mitochondrial (kinetoplast) genome stability, Essential for cell viability, Has probably no helicase activity, missing at least two of seven conserved helicase motifs

Belongs to the helicase family, PIF1 subfamily


This is Large ribosomal subunit protein uL30m protein, from Bovine, contains 161 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL30 family


This is Glial fibrillary acidic protein protein, from Zebrafish, contains 444 amino acids, is soluble, locates in Cytoplasm.

Belongs to the intermediate filament family


This is Secreted protein PRY1 protein, from Yeast, contains 410 amino acids, is soluble, locates in Extracellular.

Secreted protein that acts as a virulence factor during infections


This is N-acetylglucosamine-induced protein 1 protein, from Yeast, contains 254 amino acids, is soluble, locates in Cytoplasm.

N-acetylglucosamine-induced protein which plays a role in the N-acetylglucosamine metabolic pathway


This is Protein mesA protein, from Aspergillus nidulans, contains 791 amino acids, is soluble, locates in Cytoplasm.

Required for the formation of actin cables at hyphal tips, Involved in establishment and maintenance of hyphal polarity axes, Stabilizes the localization of the formin sepA at sites of polarized growth


This is Large ribosomal subunit protein mL41 protein, from Rat, contains 134 amino acids, locates in Mitochondrion.

Component of the mitochondrial ribosome large subunit, Also involved in apoptosis and cell cycle, Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition, Enhances p53/TP53 translocation to the mitochondria, Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins

Belongs to the mitochondrion-specific ribosomal protein mL41 family


This is HSPB1-associated protein 1 protein, from Rat, contains 479 amino acids, is soluble, locates in Cytoplasm.

May play a role in cellular stress response


This is Scygonadin protein, from Mud crab, contains 126 amino acids, is soluble, locates in Extracellular.

Has antibacterial activity against the Gram-positive bacterium M,luteus with an IC(90) of 125ug/ml, Has weak antibacterial activity against the Gram-negative bacterium A,hydrophila


This is Protein Tex24 protein, from Mouse, contains 351 amino acids, locates in Nucleus.

Nuclear factor which might have a role in spermatogenesis


This is Janus kinase and microtubule-interacting protein 3 protein, from Mouse, contains 844 amino acids, locates in Golgi apparatus.


This is Icarapin protein, from Carniolan honeybee, contains 223 amino acids, is soluble, locates in Extracellular.


This is Glycoprotein endo-alpha-1,2-mannosidase protein, from Rat, contains 462 amino acids, is membrane-bound, locates in Golgi apparatus.

Belongs to the glycosyl hydrolase 99 family


This is XK-related protein 3 protein, from Human, contains 459 amino acids, is membrane-bound, locates in Cell membrane.


This is Guanine nucleotide-binding protein subunit beta protein, from Akoya pearl oyster, contains 341 amino acids, is soluble, locates in Cytoplasm.

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems, The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction

Belongs to the WD repeat G protein beta family


This is Protein TOC75-4, chloroplastic protein, from Mouse-ear cress, contains 396 amino acids, is membrane-bound, locates in Plastid.

Mediates the insertion of proteins targeted to the outer membrane of chloroplasts, Required for the import of protein precursors into chloroplasts, Forms the voltage-dependent preprotein translocation channels (hydrophilic beta barrel) of the TOC complex in the chloroplastic outer membrane (By similarity), Required for etioplast formation and/or etioplast-chloroplast transition during deetiolation


This is Dipeptidyl peptidase 4 protein, from Athlete's foot fungus, contains 775 amino acids, is soluble, locates in Extracellular.

Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline, Contributes to pathogenicity


This is rRNA methyltransferase 3, mitochondrial protein, from Mouse, contains 418 amino acids, locates in Mitochondrion.

S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA

Belongs to the class IV-like SAM-binding methyltransferase superfamily, RNA methyltransferase TrmH family


This is LETM1 domain-containing protein LETM2, mitochondrial protein, from Rat, contains 459 amino acids, is membrane-bound, locates in Mitochondrion.


This is Endo-1,4-beta-xylanase A protein, from Penicillium canescens, contains 327 amino acids, is soluble, locates in Extracellular.

Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose

Belongs to the glycosyl hydrolase 10 (cellulase F) family


This is Putative monooxygenase p33MONOX protein, from Rat, contains 304 amino acids, is soluble, locates in Cytoplasm.

Potential NADPH-dependent oxidoreductase, May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth (By similarity)


This is Protein FAR1-RELATED SEQUENCE 1 protein, from Mouse-ear cress, contains 687 amino acids, has 1 SWIM-type Zinc finger, locates in Nucleus.

SWIM-type

Putative transcription activator involved in regulating light control of development


This is Short neurotoxin 1 protein, from Spiny-headed seasnake, contains 81 amino acids, is soluble, locates in Extracellular.

Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission

Belongs to the snake three-finger toxin family, Short-chain subfamily, Type I alpha-neurotoxin sub-subfamily


This is Cystatin-9 protein, from Human, contains 159 amino acids, is soluble, locates in Extracellular.

May be involved in testis development (By similarity), May play a role in hematopoietic differentiation or inflammation (PubMed:12535658), Has immunomodulatory and antimicrobial functions against Francisella tularensis, a Gram-negative bacteria (PubMed:23922243)


This is Protein FAM53A protein, from Chicken, contains 418 amino acids, locates in Nucleus.

May play an important role in neural development; the dorsomedial roof of the third ventricle


This is Meiotic recombination protein SPO11-1 protein, from Rice, contains 381 amino acids, locates in Nucleus.

Required for meiotic recombination, Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination (By similarity), May be involved in plant growth and development, and stress tolerance


This is Hypoxia up-regulated protein 1 protein, from Chinese hamster, contains 999 amino acids, is soluble, locates in Endoplasmic reticulum.

Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation, May play a role as a molecular chaperone and participate in protein folding (By similarity)

Belongs to the heat shock protein 70 family


This is Cx9C motif-containing protein 4 protein, from Mouse, contains 68 amino acids, locates in Mitochondrion.


This is Cell division cycle protein 123 homolog protein, from Rat, contains 336 amino acids, is soluble, locates in Cytoplasm.

Required for S phase entry of the cell cycle


This is Protein FRG2 protein, from Human, contains 278 amino acids, locates in Nucleus.


This is Subtilisin-like protease 3 protein, from Trichophyton mentagrophytes, contains 397 amino acids, is soluble, locates in Extracellular.

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity


This is Subtilisin-like protease 7 protein, from Trichophyton mentagrophytes, contains 400 amino acids, is soluble, locates in Extracellular.


This is Nuclear pore complex protein Nup93 protein, from Rat, contains 819 amino acids, is membrane-bound, locates in Nucleus.

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance, May anchor nucleoporins, but not NUP153 and TPR, to the NPC, During renal development, regulates podocyte migration and proliferation through SMAD4 signaling

Belongs to the nucleoporin interacting component (NIC) family


This is T-cell activation inhibitor, mitochondrial protein, from Mouse, contains 499 amino acids, locates in Mitochondrion.


This is Coiled-coil domain-containing protein 78 protein, from African clawed frog, contains 559 amino acids, is soluble, locates in Cytoplasm.

Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles, Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells (G1/0) and not in S phase, Essential for centriole amplification and is required for cep152 localization to the deuterosome


This is Barrier-to-autointegration factor B protein, from African clawed frog, contains 90 amino acids, locates in Nucleus.

Non-specific DNA-binding protein that plays key roles in mitotic nuclear reassembly, chromatin organization, DNA damage response, gene expression and intrinsic immunity against foreign DNA, Contains two non-specific double-stranded DNA (dsDNA)-binding sites which promote DNA cross-bridging, Plays a key role in nuclear membrane reformation at the end of mitosis by driving formation of a single nucleus in a spindle-independent manner, Transiently cross-bridges anaphase chromosomes via its ability to bridge distant DNA sites, leading to the formation of a dense chromatin network at the chromosome ensemble surface that limits membranes to the surface, Also acts as a negative regulator of innate immune activation by restricting CGAS activity toward self-DNA upon acute loss of nuclear membrane integrity, Outcompetes CGAS for DNA-binding, thereby preventing CGAS activation and subsequent damaging autoinflammatory responses, Also involved in DNA damage response; acts by inhibiting the ADP-ribosyltransferase activity of PARP1, Involved in the recognition of exogenous dsDNA in the cytosol: associates with exogenous dsDNA immediately after its appearance in the cytosol at endosome breakdown and is required to avoid autophagy


This is Potassium transporter 10 protein, from Rice, contains 843 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Belongs to the HAK/KUP transporter (TC 2,A,72,3) family


This is Protein BOLA1, chloroplastic protein, from Mouse-ear cress, contains 160 amino acids, locates in Plastid.

May act either alone or in interaction with glutaredoxin as a redox-regulated transcriptional regulator, or as a factor regulating Fe-S cluster biogenesis (Probable), The glutaredoxin-BOLA1 heterodimers bind a labile, oxygen sensitive iron-sulfur cluster (PubMed:24714563)


This is Subtilisin-like protease 4 protein, from Athlete's foot fungus, contains 399 amino acids, is soluble, locates in Extracellular.


This is Subtilisin-like protease 3 protein, from Athlete's foot fungus, contains 397 amino acids, is soluble, locates in Extracellular.


This is Chitin-inducible gibberellin-responsive protein 1 protein, from Rice, contains 571 amino acids, locates in Nucleus.

May play a regulatory role in the early step of oligosaccharide elicitor response, downstream of the membrane-associated high-affinity chitin-binding protein


This is Cytochrome P450 4X1 protein, from Mouse, contains 507 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

A cytochrome P450 monooxygenase that selectively catalyzes the epoxidation of the last double bond of the arachidonoyl moiety of anandamide, potentially modulating endocannabinoid signaling, Has no hydroxylase activity toward various fatty acids, steroids and prostaglandins, Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase)


This is Protein ALWAYS EARLY 1 protein, from Mouse-ear cress, contains 971 amino acids, locates in Nucleus.


This is U1-sicaritoxin-Li1a protein, from Brown spider, contains 101 amino acids, is soluble, locates in Extracellular.

Toxin active against insects (S,frugiperda larvae), May act on sodium (Nav) or calcium channels (Cav)

Belongs to the neurotoxin 28 (Litx) family


This is Small ribosomal subunit protein uS14m protein, from Bovine, contains 128 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uS14 family


This is Ras-related protein Rab-7b protein, from Paramecium octaurelia, contains 206 amino acids, is soluble, locates in Cytoplasm.

Belongs to the small GTPase superfamily, Rab family