This is Long neurotoxin 2 protein, from King cobra, contains 73 amino acids, is soluble, locates in Extracellular.


This is Long neurotoxin 1 protein, from King cobra, contains 73 amino acids, is soluble, locates in Extracellular.

Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission

Belongs to the snake three-finger toxin family, Long-chain subfamily, Type II alpha-neurotoxin sub-subfamily


This is Long neurotoxin 2 protein, from Forest cobra, contains 71 amino acids, is soluble, locates in Extracellular.

Binds with high affinity to muscular (alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission (PubMed:33672715), Ranges of nAChR inhibition are in nanomolar (competitive binding with alpha-bungarotoxin gives Ki=2,17 nM on muscle nAChR and Ki=26,9 nM on alpha-7) (PubMed:33672715), Also shows low inhibition on GABA(A) receptors (IC(50)~10 uM on all receptors tested: alpha-1-beta-3-gamma-2 (GABRA1-GABRB3-GABRG2), alpha-1-beta-2-gamma-2 (GABRA1-GABRB2-GABRG2), and alpha-3-beta-2-gamma-2 (GABRA3-GABRB2-GABRG2)) (PubMed:33672715)


This is Long neurotoxin 1 protein, from Anchieta's cobra, contains 72 amino acids, is soluble, locates in Extracellular.


This is Long neurotoxin 1 protein, from Cape cobra, contains 71 amino acids, is soluble, locates in Extracellular.


This is Alpha-elapitoxin-Djk2a protein, from Eastern Jameson's mamba, contains 72 amino acids, is soluble, locates in Extracellular.


This is Alpha-elapitoxin-Dv2b protein, from Western green mamba, contains 72 amino acids, is soluble, locates in Extracellular.


This is Alpha-elapitoxin-Dv2a protein, from Western green mamba, contains 73 amino acids, is soluble, locates in Extracellular.


This is Alpha-elapitoxin-Dpp2a protein, from Black mamba, contains 72 amino acids, is soluble, locates in Extracellular.


This is Synergistic-type venom protein C9S3, chain 2 protein, from Eastern green mamba, contains 63 amino acids, is soluble, locates in Extracellular.

This protein shows a synergetic toxic effect in that it enhances the toxicity of other D,angusticeps toxins

Belongs to the snake three-finger toxin family, Short-chain subfamily, Aminergic toxin sub-subfamily


This is Weak toxin DE-1 protein, from King cobra, contains 83 amino acids, is soluble, locates in Extracellular.

Belongs to the snake three-finger toxin family, Short-chain subfamily, Type I alpha-neurotoxin sub-subfamily


This is Toxin FS-2 protein, from Black mamba, contains 60 amino acids, is soluble, locates in Extracellular.

Specific blocker of the voltage-dependent L-type calcium channel (Cav1/CACNA1) (PubMed:8826098), Inhibits cardiac contractions (By similarity)

Belongs to the snake three-finger toxin family, Short-chain subfamily, L-type calcium blocker sub-subfamily


This is Short neurotoxin 1 protein, from Black mamba, contains 60 amino acids, is soluble, locates in Extracellular.

Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission


This is Short neurotoxin 1 protein, from Eastern Jameson's mamba, contains 60 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 1 protein, from Western green mamba, contains 60 amino acids, is soluble, locates in Extracellular.


This is Toxin S5C10 protein, from Eastern Jameson's mamba, contains 58 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 3 protein, from Banded Egyptian cobra, contains 61 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 4 protein, from Banded Egyptian cobra, contains 61 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 2 protein, from Banded Egyptian cobra, contains 61 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 2 protein, from Cape cobra, contains 61 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 1 protein, from Rinkhals, contains 61 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 1 protein, from Red spitting cobra, contains 61 amino acids, is soluble, locates in Extracellular.

Binds with high affinity to muscular nicotinic acetylcholine receptors (nAChRs) (tested on Torpedo marmorata AChR, Kd=0,07 nM) and with low affinity to neuronal alpha-7/CHRNA7 nAChRs (tested on chimeric receptor, Kd=3 uM) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission (PubMed:9305882), Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site


This is Short neurotoxin 1 protein, from Central Asian cobra, contains 61 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 1 protein, from Mozambique spitting cobra, contains 62 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 3 protein, from Mozambique spitting cobra, contains 62 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 2 protein, from Rinkhals, contains 61 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 1 protein, from Common death adder, contains 62 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 1 protein, from Persian gulf sea snake, contains 60 amino acids, is soluble, locates in Extracellular.

Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission (By similarity), The recombinant protein also barely blocks voltage-gated potassium channel Kv1,3/KCNA3 (2,71% inhibition at 60 nM of toxin) (PubMed:30648553)


This is Small ribosomal subunit protein eS17A protein, from Baker's yeast, contains 136 amino acids, is soluble, locates in Cytoplasm.

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel

Belongs to the eukaryotic ribosomal protein eS17 family


This is Transposable element Tc1 transposase protein, from Caenorhabditis elegans, contains 273 amino acids, locates in Nucleus.

Probably essential for transposable element Tc1 transposition, The insertion of Tc1 is the main cause of spontaneous mutations, It is an endonuclease which can produce a single strand nick at the 5'-end of the transposon


This is Serine protease inhibitor Kazal-type 1 protein, from Dog, contains 57 amino acids, is soluble, locates in Extracellular.

In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production


This is Conopressin-conophysin protein, from Geography cone, contains 128 amino acids, is soluble, locates in Extracellular.

Targets vasopressin-oxytocin related receptors (PubMed:32155768), Is more active on fish receptors than on their human counterparts, supporting an evolved role of this conopressin in the envenomation process (PubMed:32155768), Acts as an agonist on zebrafish vasopressin receptors V1a1R (EC(50)=10,6 nM), V1a2R (EC(50)=44,06 nM, partial agonist), V2R (EC(50)=299,2 nM) and oxytocin receptor (EC(50)=353,73 nM, partial agonist) (PubMed:32155768), Shows a weaker activity on human receptors AVPR1B (EC(50)=51,92 nM), AVPR1A (EC(50)=123,78 nM), AVPR2 (EC(50)=299,2 nM) and oxytocin (OXTR) receptor (EC(50)=455,66 nM, partial agonist), In vivo, exhibits grooming and scratching behavior in mice, following intracerebral injection (PubMed:3680228)

Belongs to the vasopressin/oxytocin family


This is Pathogenesis-related protein 1B protein, from Common tobacco, contains 168 amino acids, locates in Lysosome/Vacuole.

Probably involved in the defense reaction of plants against pathogens


This is COX3 mRNA-specific translational activator PET494 protein, from Baker's yeast, contains 489 amino acids, is membrane-bound, locates in Mitochondrion.

Required for the expression of the mitochondrial gene for cytochrome c oxidase subunit III (COX3)


This is Ice-structuring protein SP1-C protein, from Ocean pout, contains 87 amino acids, is soluble, locates in Extracellular.

Contributes to protect fish blood from freezing at subzero sea water temperatures, Lowers the blood freezing point, Binds to nascent ice crystals and prevents further growth (By similarity)


This is Plastocyanin protein, from Green seaweed, contains 98 amino acids, is membrane-bound, locates in Plastid.

Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I


This is BPI fold-containing family A member 2 protein, from Mouse, contains 235 amino acids, is soluble, locates in Extracellular.

Has strong antibacterial activity against P, aeruginosa

Belongs to the BPI/LBP/Plunc superfamily, Plunc family


This is Pathogenesis-related protein 1A protein, from Common tobacco, contains 168 amino acids, locates in Lysosome/Vacuole.


This is Luciferin 4-monooxygenase protein, from Common eastern firefly, contains 550 amino acids, locates in Peroxisome.

Produces green light with a wavelength of 562 nm

Belongs to the ATP-dependent AMP-binding enzyme family


This is Pathogenesis-related protein 1C protein, from Common tobacco, contains 168 amino acids, locates in Lysosome/Vacuole.


This is Bilin-binding protein protein, from White butterfly, contains 189 amino acids, is soluble, locates in Extracellular.

This protein binds the blue pigments bilins

Belongs to the calycin superfamily, Lipocalin family


This is Potassium channel toxin alpha-KTx 18.3 protein, from Venezuelan scorpion, contains 62 amino acids, is soluble, locates in Extracellular.

Probable voltage-gated potassium channel inhibitor

Belongs to the short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 18 subfamily


This is Large ribosomal subunit protein mL52 protein, from Bovine, contains 124 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mL52 family


This is Large ribosomal subunit protein mL55 protein, from Bovine, contains 126 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mL55 family


This is Large ribosomal subunit protein eL27B protein, from Baker's yeast, contains 136 amino acids, is soluble, locates in Cytoplasm.

Belongs to the eukaryotic ribosomal protein eL27 family


This is Neurotoxin 3FTx-RK protein, from Banded krait, contains 86 amino acids, is soluble, locates in Extracellular.

Belongs to the snake three-finger toxin family, Short-chain subfamily, Orphan group III sub-subfamily


This is Protein ten1 protein, from Fission yeast, contains 102 amino acids, locates in Nucleus.


This is Disintegrin EMS11A protein, from Central Asian sand viper, contains 68 amino acids, is soluble, locates in Extracellular.

Poor inhibitor of platelet aggregation, The disintegrin inhibits the adhesion of both the alpha-4/beta-1 (ITGA4/ITGB1) and the alpha-5/beta-1 (ITGA5/ITGB1) integrins to VCAM-1 and fibronectin respectively with almost the same degree of specificity, Inhibition on alpha-IIb/beta-3 (ITGA2B/ITGB3) is low

Belongs to the disintegrin family, Dimeric disintegrin subfamily


This is Disintegrin EO5B protein, from Ocellated saw-scaled viper, contains 66 amino acids, is soluble, locates in Extracellular.

Poor inhibitor of platelet aggregation, When it dimerizes with EO4A, it inhibits the adhesion of cells expressing the RGD-dependent integrin alpha-5/beta-1 (ITGA5/ITGB1) to immobilized fibronectin, When it dimerizes with EO5A, it inhibits the adhesion of the alpha-4/beta-1 (ITGA4/ITGB1) integrin to VCAM-1, When it dimerizes either with EO4A or EO5A, the inhibition on alpha-IIb/beta-3 (ITGA2B/ITGB3) is low


This is Disintegrin VA6 protein, from Western sand viper, contains 64 amino acids, is soluble, locates in Extracellular.

Poor inhibitor of platelet aggregation, The disintegrin inhibits the adhesion of cells expressing the RGD-dependent integrin alpha-5/beta-1 (ITGA5/ITGB1) to immobilized fibronectin, Inhibition on alpha-IIb/beta-3 (ITGA2B/ITGB3) is low, and there is no inhibition on alpha-1/beta-1 (ITGA1/ITGB1), alpha-2/beta-1 (ITGA2/ITGB1) and alpha-6/beta-1 (ITGA6/ITGB1)

Belongs to the venom metalloproteinase (M12B) family, P-II subfamily, P-IId sub-subfamily


This is Disintegrin VB7A protein, from Common viper, contains 64 amino acids, is soluble, locates in Extracellular.

Poor inhibitor of platelet aggregation, The disintegrin inhibits the adhesion of cells expressing the RGD-dependent integrin alpha-5/beta-1 (ITGA5/ITGB1) to immobilized fibronectin, Inhibition on alpha-2b/beta-3 (ITGA2B/ITGB3) is low


This is Disintegrin VB7B protein, from Common viper, contains 64 amino acids, is soluble, locates in Extracellular.

Poor inhibitor of platelet aggregation, The disintegrin inhibits the adhesion of cells expressing the RGD-dependent integrin alpha-5/beta-1 (ITGA5/ITGB1) to immobilized fibronectin, Inhibition on alpha-IIb/beta-3 (ITGA2B/ITGB3) is low

Belongs to the venom metalloproteinase (M12B) family, P-II subfamily, P-IIe sub-subfamily


This is Disintegrin VLO4 protein, from Levant blunt-nosed viper, contains 65 amino acids, is soluble, locates in Extracellular.


This is Disintegrin VLO5A protein, from Levant blunt-nosed viper, contains 64 amino acids, is soluble, locates in Extracellular.

Poor inhibitor of platelet aggregation, The disintegrin inhibits the adhesion of the alpha-4/beta-1 (ITGA4/ITGB1) integrin to VCAM-1, Inhibition on alpha-IIb/beta-3 (ITGA2B/ITGB3) is low


This is Disintegrin VLO5B protein, from Levant blunt-nosed viper, contains 69 amino acids, is soluble, locates in Extracellular.

Poor inhibitor of platelet aggregation, The disintegrin inhibits the adhesion of the alpha-4/beta-1 (ITGA4/ITGB1) integrin to VCAM-1, Inhibition on alpha-2b/beta-3 (ITGA2B/ITGB3) is low


This is Age-related maculopathy susceptibility protein 2 protein, from Human, contains 107 amino acids, is soluble, locates in Cytoplasm.


This is Potassium channel toxin gamma-KTx 1.7 protein, from Bark scorpion, contains 42 amino acids, is soluble, locates in Extracellular.

Blocks in a reversible manner human and rat Kv11,1/KCNH2/ERG1 potassium channels, Also completely and irreversibly blocks rat Kv11,2/KCNH6/ERG2 and human Kv11,3/KCNH7/ERG3 channels

Belongs to the ergtoxin family, Gamma-KTx 1 subfamily


This is Potassium channel toxin gamma-KTx 1.8 protein, from Bark scorpion, contains 42 amino acids, is soluble, locates in Extracellular.

Blocks in a reversible manner human and rat Kv11,1/KCNH2/ERG1 potassium channels (PubMed:18338253), Also completely and irreversibly blocks rat Kv11,2/KCNH6/ERG2 and human Kv11,3/KCNH7/ERG3 channels (PubMed:18338253), Also weakly inhibits Kir2,1/KCNJ2 and Kv1,2/KCNA2 potassium channels (PubMed:29483648)


This is Snaclec bothroinsularin subunit alpha protein, from Golden lancehead, contains 132 amino acids, is soluble, locates in Extracellular.

Thrombin and prothrombin (F2) inhibitor, The IC(50) of thrombin-induced platelet aggregation and fibrinocoagulation is 62 and 35 nM, respectively, Its inhibitory activity is at least 10-fold lower than that observed for other thrombin inhibitors


This is Snaclec bothroinsularin subunit beta protein, from Golden lancehead, contains 127 amino acids, is soluble, locates in Extracellular.


This is V-type proton ATPase subunit E3 protein, from Mouse-ear cress, contains 237 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function, V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity)

Belongs to the V-ATPase E subunit family


This is Short neurotoxin D1 protein, from Coral snake, contains 60 amino acids, is soluble, locates in Extracellular.

Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission

Belongs to the snake three-finger toxin family, Short-chain subfamily, Type I alpha-neurotoxin sub-subfamily


This is Short neurotoxin 2 protein, from Australian taipan, contains 62 amino acids, is soluble, locates in Extracellular.


This is Bactridin-2 protein, from Venezuelan scorpion, contains 64 amino acids, is soluble, locates in Extracellular.

Shows antibacterial activity against both Gram-positive bacteria (B,subtilis, M,luteus, E,faecalis) and Gram-negative bacteria (P,aeruginosa, Y,enterocolitica, A,calcoaceticus), Modifies membrane sodium permeability on Y,enterocolitica, Is toxic to mice, but is not to crabs, Induces concentration dependent haemolysis in human erythrocytes (PubMed:19540868), Acts by inhibiting the sodium (Nav) currents (By similarity)

Belongs to the long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family, Beta subfamily


This is Bactridin-1 protein, from Venezuelan scorpion, contains 61 amino acids, is soluble, locates in Extracellular.

Shows antibacterial activity against both Gram-positive bacteria (B,subtilis, M,luteus, E,faecalis) and Gram-negative bacteria (P,aeruginosa, Y,enterocolitica, A,calcoaceticus) (PubMed:19540868), Modifies membrane sodium permeability on Y,enterocolitica (PubMed:19540868), Is toxic to cockroaches and crabs, but is not toxic to mice, Does not induce haemolysis in human erythrocytes (PubMed:19540868), Acts by inhibiting the sodium (Nav) currents (By similarity)


This is Toxin aagardi protein, from West Coast black-headed sea snake, contains 60 amino acids, is soluble, locates in Extracellular.


This is Probable phospholipase A1 magnifin protein, from Hornet, contains 337 amino acids, is soluble, locates in Extracellular.

Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity), May act as an allergen and induce hemolytic activity (By similarity), In vivo, induces dose-dependent platelet aggregation (nanomolar concentration) and induces thrombosis (PubMed:18023835)

Belongs to the AB hydrolase superfamily, Lipase family


This is Phospholipase A1 protein, from Southern yellow jacket, contains 298 amino acids, is soluble, locates in Extracellular.

Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity), May act as an allergen and induce hemolytic activity (By similarity)


This is Phospholipase A1 protein, from European hornet, contains 301 amino acids, is soluble, locates in Extracellular.


This is Formate dehydrogenase 2 protein, from Baker's yeast, contains 376 amino acids, is soluble, locates in Cytoplasm.

Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide, Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms, Has a role in the detoxification of exogenous formate in non-methylotrophic organisms

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family, FDH subfamily


This is (3S,6E)-nerolidol synthase 1, chloroplastic protein, from Woodland strawberry, contains 580 amino acids, locates in Plastid.

Involved in monoterpene (C10) and sesquiterpene (C15) biosynthesis, Converts geranyl diphosphate (GPP) into S-linalool and farnesyl diphosphate (FPP) into (3S)-E-nerolidol (By similarity), Probably not expressed in wild strawberry species

Belongs to the terpene synthase family, Tpsg subfamily


This is Large ribosomal subunit protein eL20B protein, from Baker's yeast, contains 172 amino acids, is soluble, locates in Cytoplasm.

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell, The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules, The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain, The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel

Belongs to the eukaryotic ribosomal protein eL20 family


This is Polycomb group protein FERTILIZATION-INDEPENDENT SEED 2 protein, from Mouse-ear cress, contains 755 amino acids, has 1 C2H2-type Zinc finger, locates in Nucleus.

Polycomb group (PcG) protein, PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development, PcG proteins are not required to initiate repression, but to maintain it during later stages of development, They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility, Required to prevent the proliferation of the central cell by repressing unknown target genes before fertilization, Regulates the anteroposterior organization of the endosperm

Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family


This is Cytochrome c oxidase assembly factor 3, mitochondrial protein, from Fruit fly, contains 87 amino acids, is membrane-bound, locates in Mitochondrion.

Plays a critical role in the biogenesis and activity of cytochrome c oxidase (COX) (complex IV)


This is Mambalgin-2 protein, from Black mamba, contains 57 amino acids, is soluble, locates in Extracellular.

This three-finger toxin inhibits ASIC channels, It acts as a gating modifier toxin by decreasing the apparent proton sensitivity of activation and by slightly increasing the apparent proton sensitivity for inactivation (PubMed:24695733), It binds more tightly to the closed state and to a much lesser extent the inactivated/desensitized state of ASIC1a isoform of ASIC1 (PubMed:24695733), It interacts directly with the outside surface of the thumb domain of chicken ASIC1a (ASIC1a), but does not insert into the acidic pocket as suggested previously (By similarity), This binding leads to relocation of the thumb domain that could disrupt the acidic pocket of cASIC1a (By similarity), The peptide exerts both stimulatory and inhibitory effects on ASIC1a (PubMed:24695733), It reversibly inhibits rat ASIC1a (IC(50)=21-55 nM), rat ASIC1b (IC(50)=103-192 nM), rat ASIC1a-ASIC1b (IC(50)=72 nM), rat ASIC1a-ASIC2a (IC(50)=246-252 nM) and rat ASIC1a-ASIC2b (IC(50)=61 nM) (PubMed:23034652, PubMed:23624383, PubMed:24323786, PubMed:24695733, PubMed:26991634), In vivo, it shows a potent naloxone-resistant analgesic effect against acute and inflammatory pain upon central and peripheral injection (By similarity), In addition, it also has an opioid-independent effect on both thermal and mechanical inflammatory pain after systemic administration and is effective against neuropathic pain (By similarity)

Belongs to the snake three-finger toxin family, Short-chain subfamily, Mambalgin sub-subfamily


This is Alpha-elapitoxin-Aa2e protein, from Common death adder, contains 79 amino acids, is soluble, locates in Extracellular.

Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission (By similarity), Produces paralysis, clear dyspnea and lethality on mice (PubMed:9133710)

Belongs to the snake three-finger toxin family, Long-chain subfamily, Type II alpha-neurotoxin sub-subfamily


This is Vespin protein, from Hornet, contains 67 amino acids, is soluble, locates in Extracellular.

Shows contractile activity on isolated ileum smooth muscle


This is Snake venom vascular endothelial growth factor toxin VR-1' protein, from Eastern Russel's viper, contains 109 amino acids, is soluble, locates in Extracellular.

Snake venom VEGFs may contribute to venom dispersion and prey subjugation by inducing vascular permeability and hypotension, This protein stimulates vascular endothelial cell proliferation (EC(50)=0,2 nM) in a similar manner than VR-1 and vammin (PubMed:15992764), This angiogenesis probably occurs through VEGF receptor (KDR/VEGFR-2) signaling, Also induces drastic hypotension mediated by nitric oxide (NO), which is produced by VEGF-activated endothelium NO synthase, Also induces vascular permeability (By similarity)

Belongs to the PDGF/VEGF growth factor family, Snake venom VEGF subfamily


This is C-type lectin APL protein, from Eastern cottonmouth, contains 135 amino acids, is soluble, locates in Extracellular.

Beta-galactoside lectin that agglutinates rabbit and human erythrocytes in a calcium-dependent fashion (MHC is 0,21 ug/ml on rabbit erythrocytes), Galactose (15 mM), lactose (20 mM), rhamnose (20 mM) and EGTA strongly inhibit this activity


This is Snaclec alboaggregin-D subunit alpha protein, from White-lipped pit viper, contains 158 amino acids, is soluble, locates in Extracellular.

Snaclec that induces human platelet aggregation in the absence of any cofactor with the EC(50) of 0,25 nM and causes tyrosine phosphorylation in human platelets, Antibodies against either platelet GPIbalpha (GP1BA) or GPVI (GP6) inhibit alboaggregin D-induced platelet aggregation, Only the combination of these two antibodies completely inhibit aggregation, suggesting that it acts through both GPIbalpha (GP1BA) and GPVI (GP6)


This is Snaclec alboaggregin-D subunit beta protein, from White-lipped pit viper, contains 148 amino acids, is soluble, locates in Extracellular.


This is Protein NETWORKED 2A protein, from Mouse-ear cress, contains 947 amino acids, is membrane-bound, locates in Cell membrane.

Plant-specific actin binding protein, Associates with F-actin at the plasma membrane in growing pollen tubes, May be part of a membrane-cytoskeletal adapter complex


This is Short neurotoxin D protein, from Yellow-lipped sea krait, contains 83 amino acids, is soluble, locates in Extracellular.

Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission


This is Short neurotoxin II protein, from Yellow-lipped sea krait, contains 83 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin B protein, from Blue-ringed sea krait, contains 83 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin C protein, from Blue-ringed sea krait, contains 62 amino acids, is soluble, locates in Extracellular.


This is Small ribosomal subunit protein mS43 protein, from Baker's yeast, contains 321 amino acids, locates in Mitochondrion.

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane

Belongs to the mitochondrion-specific ribosomal protein mS43 family


This is Small ribosomal subunit protein uS14m protein, from Baker's yeast, contains 115 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uS14 family


This is Actin-4 protein, from Caenorhabditis elegans, contains 376 amino acids, is soluble, locates in Cytoplasm.

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells


This is PBAN-type neuropeptides protein, from Corn earworm moth, contains 194 amino acids, is soluble, locates in Extracellular.

A hormone that controls sex pheromone production in females and pheromone responsiveness in male, Also mediates visceral muscle contractile activity (myotropic activity)


This is Larval serum protein 1 alpha chain protein, from Fruit fly, contains 816 amino acids, is soluble, locates in Extracellular.

Larval storage protein (LSP) which may serve as a store of amino acids for synthesis of adult proteins


This is Larval serum protein 1 gamma chain protein, from Fruit fly, contains 772 amino acids, is soluble, locates in Extracellular.


This is Pseudonajatoxin b protein, from Eastern brown snake, contains 71 amino acids, is soluble, locates in Extracellular.

Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission


This is Small ribosomal subunit protein eS17B protein, from Baker's yeast, contains 136 amino acids, is soluble, locates in Cytoplasm.

Belongs to the eukaryotic ribosomal protein eS17 family


This is Long neurotoxin homolog Pa ID protein, from Mulga snake, contains 89 amino acids, is soluble, locates in Extracellular.


This is Pancreas/duodenum homeobox protein 1 protein, from African clawed frog, contains 271 amino acids, locates in Nucleus.

Acts together with ptf1a to induce the pancreatic lineage within the endoderm

Belongs to the Antp homeobox family, IPF1/XlHbox-8 subfamily


This is Cytochrome B translational activator protein CBS2 protein, from Baker's yeast, contains 389 amino acids, locates in Mitochondrion.

Translational activator of cytochrome b, The cytochrome b (coB) leader RNA may represent the target sequence for CBS1 and/ or CBS2


This is Kappa-flavitoxin protein, from Red-headed krait, contains 66 amino acids, is soluble, locates in Extracellular.

Postsynaptic neurotoxin that binds and inhibits neuronal nicotinic acetylcholine receptors (nAChR) with high affinity (IC(50)<100 nM), Is a selective, and slowly reversible antagonist of alpha-3/CHRNA3-containing and some alpha-4/CHRNA4-containing AChRs

Belongs to the snake three-finger toxin family, Long-chain subfamily, Kappa-neurotoxin sub-subfamily


This is Kappa-2-bungarotoxin protein, from Many-banded krait, contains 87 amino acids, is soluble, locates in Extracellular.


This is Kappa-3-bungarotoxin protein, from Many-banded krait, contains 87 amino acids, is soluble, locates in Extracellular.


This is Long neurotoxin homolog protein, from Many-banded krait, contains 87 amino acids, is soluble, locates in Extracellular.

Inhibits carbachol-induced muscle contraction in a reversible manner

Belongs to the snake three-finger toxin family, Ancestral subfamily, Orphan group IV sub-subfamily


This is Zinc finger protein 59 protein, from Mouse, contains 653 amino acids, has 16 C2H2-type Zinc finger, locates in Nucleus.

May have a role during differentiation processes

Belongs to the krueppel C2H2-type zinc-finger protein family


This is Mitochondrial outer membrane protein OM45 protein, from Baker's yeast, contains 393 amino acids, is membrane-bound, locates in Mitochondrion.


This is Accessory gland-specific peptide 95EF protein, from Fruit fly, contains 52 amino acids, is soluble, locates in Extracellular.

This protein may be a precursor of secreted proteins and peptide hormones


This is Plastocyanin, chloroplastic protein, from Chlamydomonas smithii, contains 145 amino acids, is membrane-bound, locates in Plastid.

Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I


This is Muscarinic toxin 2 protein, from Eastern green mamba, contains 86 amino acids, is soluble, locates in Extracellular.

Binds irreversibly to M1 (CHRM1) muscarinic acetylcholine receptors, and reveals a slightly weaker effect on M3 (CHRM3) receptors, The mechanism of toxin-receptor interaction comprises at least two steps, The first step is fast with no competition between the toxin and the antagonist, The second step is slow with formation of a more stable toxin-receptor complex and inhibition of the antagonist binding

Belongs to the snake three-finger toxin family, Short-chain subfamily, Aminergic toxin sub-subfamily


This is Arrestin-related trafficking adapter 10 protein, from Baker's yeast, contains 518 amino acids, is soluble, locates in Cytoplasm.

May regulate endocytosis by recruiting RSP5 ubiquitin ligase activity to specific plasma membrane proteins in response to extracellular stimuli


This is Type-3 ice-structuring protein HPLC 12 protein, from Ocean pout, contains 66 amino acids, is soluble, locates in Extracellular.

Contributes to protect fish blood from freezing at subzero sea water temperatures, Lowers the blood freezing point, Binds to nascent ice crystals and prevents further growth


This is Large ribosomal subunit protein mL53 protein, from Baker's yeast, contains 98 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mL53 family


This is Short neurotoxin C protein, from Olive sea snake, contains 60 amino acids, is soluble, locates in Extracellular.

Belongs to the snake three-finger toxin family, Short-chain subfamily, Type I alpha-neurotoxin sub-subfamily


This is Short neurotoxin B protein, from Olive sea snake, contains 81 amino acids, is soluble, locates in Extracellular.


This is Calciseptin protein, from Black mamba, contains 60 amino acids, is soluble, locates in Extracellular.

This specific blocker of the L-type calcium channel (Cav1/CACNA1) is a smooth muscle relaxant and an inhibitor of cardiac contractions

Belongs to the snake three-finger toxin family, Short-chain subfamily, L-type calcium blocker sub-subfamily


This is Chorion protein S16 protein, from Fruit fly, contains 138 amino acids, is soluble, locates in Extracellular.

Chorion membrane (egg shell) protein; plays a role in protecting the egg from the environment

Belongs to the chorion protein S16 family


This is Small ribosomal subunit protein uS10 protein, from African clawed frog, contains 119 amino acids, is soluble, locates in Cytoplasm.

Component of the small ribosomal subunit (By similarity), The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (By similarity)

Belongs to the universal ribosomal protein uS10 family


This is Superoxide dismutase [Cu-Zn] protein, from Onchocerca volvulus, contains 158 amino acids, is soluble, locates in Cytoplasm.

Destroys radicals which are normally produced within the cells and which are toxic to biological systems

Belongs to the Cu-Zn superoxide dismutase family


This is Cytotoxin 2 protein, from Rinkhals, contains 61 amino acids, is soluble, locates in Extracellular.

This protein lyses red blood cells, has cytotoxic activity and induces hypotension, but is not neurotoxic, In addition, it induces direct paralysis of the muscle fiber

Belongs to the snake three-finger toxin family, Short-chain subfamily, Type IB cytotoxin sub-subfamily


This is Cytotoxin 3 protein, from Rinkhals, contains 61 amino acids, is soluble, locates in Extracellular.

This protein lyses red blood cells and has cardiotoxic and hypotensive activities


This is Cytotoxin homolog protein, from Rinkhals, contains 63 amino acids, is soluble, locates in Extracellular.

Belongs to the snake three-finger toxin family, Short-chain subfamily, Orphan group XIV sub-subfamily


This is 20S rRNA accumulation protein 4 protein, from Baker's yeast, contains 408 amino acids, is soluble, locates in Cytoplasm.

Required for processing of the 20S pre-rRNA at site D to generate mature 18S rRNA


This is Copper transport protein 86 protein, from Baker's yeast, contains 563 amino acids, is soluble, locates in Cytoplasm.

Essential protein which may be involved in threonine biosynthesis


This is Short neurotoxin 1 protein, from Mulga snake, contains 83 amino acids, is soluble, locates in Extracellular.

Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission


This is Adrenergic toxin rho-elapitoxin-Dp1b protein, from Black mamba, contains 65 amino acids, is soluble, locates in Extracellular.

Highly potent on various alpha-adrenoceptors (ADRA) (subnanomolar affinity for ADRA1A), Order of potency is the following: ADRA1A (Ki=0,37 nM) > ADRA1B (Ki=10,47 nM) > ADRA1D (Ki=104,71 nM) > ADRA2C (Ki=165,96 nM), Were also found to reversibly bind to muscarinic acetylcholine receptors (CHRM), but the affinity is much weaker (CHRM1, Ki=1778,28 nM; CHRM4, Ki=4466,84 nM; CHRM2, Ki=17782,79 nM)


This is Autophagy-related protein 22 protein, from Baker's yeast, contains 528 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Vacuolar effluxer which mediate the efflux of leucine and other amino acids resulting from autophagic degradation, The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation


This is Peroxisomal membrane protein PEX34 protein, from Baker's yeast, contains 144 amino acids, is membrane-bound, locates in Peroxisome.

In concert with the three peroxisome divisional factors, PEX11, PEX25 and PEX27, controls peroxisome morphology and abundance under conditions of peroxisome proliferation, Maintains mature peroxisomes in actively dividing cells


This is Large ribosomal subunit protein mL49 protein, from Baker's yeast, contains 146 amino acids, locates in Mitochondrion.

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane

Belongs to the mitochondrion-specific ribosomal protein mL49 family


This is Alpha-elapitoxin-Dpp2b protein, from Black mamba, contains 72 amino acids, is soluble, locates in Extracellular.

Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission

Belongs to the snake three-finger toxin family, Long-chain subfamily, Type II alpha-neurotoxin sub-subfamily


This is Long neurotoxin 1 protein, from Indian cobra, contains 71 amino acids, is soluble, locates in Extracellular.


This is Long neurotoxin 1 protein, from Shield-nose snake, contains 68 amino acids, is soluble, locates in Extracellular.


This is Long neurotoxin 3 protein, from Indian cobra, contains 71 amino acids, is soluble, locates in Extracellular.


This is Long neurotoxin 4 protein, from Indian cobra, contains 71 amino acids, is soluble, locates in Extracellular.


This is Long neurotoxin 1 protein, from Egyptian cobra, contains 71 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 2 protein, from Egyptian cobra, contains 61 amino acids, is soluble, locates in Extracellular.


This is Toxin S4C8 protein, from Eastern Jameson's mamba, contains 60 amino acids, is soluble, locates in Extracellular.


This is Toxin MIT1 protein, from Black mamba, contains 81 amino acids, is soluble, locates in Extracellular.

Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2 (PubMed:12054613), Potently contracts gastrointestinal (GI) smooth muscle (PubMed:10567694)

Belongs to the AVIT (prokineticin) family


This is Plastocyanin, chloroplastic protein, from Green alga, contains 145 amino acids, is membrane-bound, locates in Plastid.

Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I


This is Small ribosomal subunit protein bS6m protein, from Baker's yeast, contains 131 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bS6 family


This is Acidic endochitinase protein, from Common tobacco, contains 291 amino acids, is soluble, locates in Extracellular.

This protein functions as a defense against chitin containing fungal pathogens

Belongs to the glycosyl hydrolase 18 family, Chitinase class II subfamily


This is U2-ctenitoxin-Pn1a protein, from Brazilian armed spider, contains 88 amino acids, is soluble, locates in Extracellular.

Inhibits voltage-gated sodium channels (Nav) (By similarity), Causes scratching, lacrimation, hypersalivation, sweating and agitation followed by spastic paralysis of the anterior and posterior extremities and death at dose levels of 1,62 mg/mouse, Insecticidal to the larval and adult forms of the house fly

Belongs to the neurotoxin 03 (Tx2) family, 04 subfamily


This is Transthyretin protein, from Shingleback lizard, contains 150 amino acids, is soluble, locates in Extracellular.

Thyroid hormone-binding protein, Probably transports thyroxine from the bloodstream to the brain


This is Large ribosomal subunit protein mL61 protein, from Baker's yeast, contains 137 amino acids, locates in Mitochondrion.

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane (PubMed:24675956, PubMed:25609543), mL61 is not essential in cells grown at 30 degree Celsius but is required for mitochondrial translation in cells grown at 18 degree Celsius

Belongs to the mitochondrion-specific ribosomal protein mL61 family


This is Probable prephenate dehydratase protein, from Baker's yeast, contains 334 amino acids, is soluble, locates in Cytoplasm.

Catayzes the decarboxylation/dehydration of prephenate to phenylpyruvate


This is ATPase expression protein 1, mitochondrial protein, from Baker's yeast, contains 518 amino acids, locates in Mitochondrion.

Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase


This is Protein ECM25 protein, from Baker's yeast, contains 599 amino acids, is soluble, locates in Cytoplasm.

May be involved in cell wall organization and biogenesis


This is Altered inheritance of mitochondria protein 26, mitochondrial protein, from Baker's yeast, contains 118 amino acids, is membrane-bound, locates in Mitochondrion.

Involved in selective mitochondria autophagy (mitophagy)


This is Short neurotoxin A protein, from Olive sea snake, contains 60 amino acids, is soluble, locates in Extracellular.


This is Long neurotoxin 1 protein, from Banded water cobra, contains 71 amino acids, is soluble, locates in Extracellular.

Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and hinders acetylcholine binding to the receptor, thereby impairing neuromuscular and neuronal transmission


This is Short neurotoxin 1 protein, from Banded water cobra, contains 61 amino acids, is soluble, locates in Extracellular.

Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission


This is Short neurotoxin 1 protein, from Christy's water cobra, contains 62 amino acids, is soluble, locates in Extracellular.


This is cAMP-binding protein 2 protein, from Social amoeba, contains 287 amino acids, locates in Nucleus.


This is Uncharacterized protein YKL187C protein, from Baker's yeast, contains 750 amino acids, locates in Mitochondrion.


This is Spindle assembly abnormal protein 4 protein, from Caenorhabditis elegans, contains 808 amino acids, is soluble, locates in Cytoplasm.

Required for centrosome duplication, Plays a central role in determining centrosome size


This is Chromo domain-containing protein cec-1 protein, from Caenorhabditis elegans, contains 304 amino acids, locates in Nucleus.


This is Cytochrome b termination protein 1 protein, from Baker's yeast, contains 271 amino acids, locates in Mitochondrion.

Involved in 5'-end processing of mitochondrial COB, 15S rRNA, and RPM1 transcript, May also have a role in 3'-end processing of the COB pre-mRNA


This is Helper of Tim protein 13 protein, from Baker's yeast, contains 116 amino acids, has 1 CHY-type; degenerate Zinc finger, is membrane-bound, locates in Mitochondrion.

CHY-type; degenerate

Required for the assembly or recycling of the small Tim proteins in the mitochondrial intermembrane, thereby participating in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane, Probably acts by facilitating the formation of disulfide bonds in small Tim proteins


This is Putative redox protein FMP46, mitochondrial protein, from Baker's yeast, contains 133 amino acids, locates in Mitochondrion.

Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules


This is SPARC protein, from African clawed frog, contains 300 amino acids, is soluble, locates in Extracellular.

Appears to regulate cell growth through interactions with the extracellular matrix and cytokines, Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes, There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity)


This is Mitochondrial intermediate peptidase protein, from Split gill fungus, contains 775 amino acids, is soluble, locates in Mitochondrion.

Cleaves proteins, imported into the mitochondrion, to their mature size, While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity)


This is Probable metabolite transport protein YBR241C protein, from Baker's yeast, contains 488 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Belongs to the major facilitator superfamily, Sugar transporter (TC 2,A,1,1) family


This is Vacuolar amino acid transporter 5 protein, from Baker's yeast, contains 459 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Probable amino acid transporter of unknown specificity

Belongs to the amino acid/polyamine transporter 2 family


This is Oligosaccharide translocation protein RFT1 protein, from Baker's yeast, contains 574 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Involved in N-linked oligosaccharide assembly, Required for the translocation of Man(5)GlcNAc(2)-PP-dolichol from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane


This is Altered inheritance of mitochondria protein 4 protein, from Baker's yeast, contains 123 amino acids, is soluble, locates in Cytoplasm.


This is Protein SDS24 protein, from Baker's yeast, contains 527 amino acids, is soluble, locates in Cytoplasm.

Involved in DNA replication and cell separation during budding


This is YAP1-binding protein 1 protein, from Baker's yeast, contains 674 amino acids, is soluble, locates in Cytoplasm.

Involved in oxidative stress response and redox homeostasis, Required for hydrogen peroxide-induced oxidation and nuclear localization (activation) of YAP1, Functions probably in concert with HYP1/GPX3, the actual YAP1 modifying enzyme, YBP1 is not required for HYP1/GPX3-independent, diamide-induced oxidation of YAP1


This is Putative aldehyde dehydrogenase-like protein YHR039C protein, from Baker's yeast, contains 644 amino acids, locates in Endoplasmic reticulum.

Belongs to the aldehyde dehydrogenase family


This is Oxidant-induced cell-cycle arrest protein 5 protein, from Baker's yeast, contains 679 amino acids, is soluble, locates in Cytoplasm.

Required for replication of brome mosaic virus (BMV), a positive-strand RNA virus


This is Ribosome-recycling factor, mitochondrial protein, from Baker's yeast, contains 230 amino acids, locates in Mitochondrion.

Necessary for protein synthesis in mitochondria, Functions as a ribosome recycling factor in mitochondria


This is Hydroxyacyl-thioester dehydratase type 2, mitochondrial protein, from Baker's yeast, contains 280 amino acids, locates in Mitochondrion.

Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, Required for respiratory growth and for normal mitochondrial morphology


This is Protein LIN1 protein, from Baker's yeast, contains 340 amino acids, locates in Nucleus.


This is Peptidyl-tRNA hydrolase protein, from Baker's yeast, contains 190 amino acids, locates in Mitochondrion.

Peptidyl-tRNA hydrolase involved in the recycling of tRNA-Lys from diacetyl-lysyl-tRNA-Lys and is important for mitochondrial function


This is Altered inheritance of mitochondria protein 18, mitochondrial protein, from Baker's yeast, contains 321 amino acids, locates in Mitochondrion.


This is Altered inheritance of mitochondria protein 46, mitochondrial protein, from Baker's yeast, contains 310 amino acids, locates in Mitochondrion.


This is Adult enhancer factor 1 protein, from Fruit fly, contains 308 amino acids, has 4 C2H2-type Zinc finger, locates in Nucleus.

Transcriptional repressor that binds specifically to fat body-specific enhancers, namely the adult ADH enhancer (AAE) and the enhancer that controls yolk protein gene expression


This is 3-oxoacyl-[acyl-carrier-protein] synthase homolog protein, from Baker's yeast, contains 442 amino acids, locates in Mitochondrion.

Possibly involved in the synthesis of a specialized molecule, probably related to a fatty acid, which is essential for mitochondrial respiration, Is essential for oxygen uptake and the presence of cytochromes A and B

Belongs to the thiolase-like superfamily, Beta-ketoacyl-ACP synthases family


This is Probable proline--tRNA ligase, mitochondrial protein, from Baker's yeast, contains 576 amino acids, locates in Mitochondrion.

Belongs to the class-II aminoacyl-tRNA synthetase family


This is Vacuolar amino acid transporter 2 protein, from Baker's yeast, contains 480 amino acids, is membrane-bound, locates in Lysosome/Vacuole.


This is Histone H2A.Z-specific chaperone CHZ1 protein, from Baker's yeast, contains 153 amino acids, locates in Nucleus.

Forms a chaperone-bound H2A,Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A,Z histone replacement in chromatin


This is Transcription factor VHR2 protein, from Baker's yeast, contains 505 amino acids, locates in Nucleus.

Transcription factor that regulates ERG9, but seems to have a more global function in transcription


This is MIOREX complex component 1 protein, from Baker's yeast, contains 688 amino acids, locates in Mitochondrion.

Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression


This is Ino eighty subunit 5 protein, from Baker's yeast, contains 125 amino acids, locates in Nucleus.


This is Respiratory growth induced protein 2 protein, from Baker's yeast, contains 164 amino acids, is soluble, locates in Cytoplasm.

Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions


This is Protein SIP5 protein, from Baker's yeast, contains 489 amino acids, is soluble, locates in Cytoplasm.

May negatively regulate the SNF1 kinase by promoting the interaction of the REG1/GLC7 phosphatase complex with the kinase, Deletion of SIP5 promotes resistance to artimisin, which is probably an indirect effect of an action on the electron transport chain


This is Proline-rich protein HUA1 protein, from Baker's yeast, contains 198 amino acids, is soluble, locates in Cytoplasm.

May be involved in assembly and disassembly of the actin cytoskeleton


This is Nucleolar protein SWM2 protein, from Baker's yeast, contains 146 amino acids, locates in Nucleus.


This is Altered inheritance of mitochondria protein 20 protein, from Baker's yeast, contains 204 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Involved in cell cycle progression and surviving DNA damage


This is Protein VHS2 protein, from Baker's yeast, contains 436 amino acids, is soluble, locates in Cytoplasm.

Can suppress the synthetic lethality of the hal3 sit4 double mutation when overexpressed, suggesting that it is involved in the G1-S transition


This is Putative zinc metalloproteinase YIL108W protein, from Baker's yeast, contains 696 amino acids, is soluble, locates in Cytoplasm.


This is ATP synthase assembly factor FMC1, mitochondrial protein, from Baker's yeast, contains 155 amino acids, locates in Mitochondrion.

Needed for the assembly of the mitochondrial F1-F0 complex at high temperature


This is Small ribosomal subunit protein mS23 protein, from Baker's yeast, contains 264 amino acids, locates in Mitochondrion.

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane

Belongs to the mitochondrion-specific ribosomal protein mS23 family


This is Zinc transporter YKE4 protein, from Baker's yeast, contains 346 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Zinc transporter whose role depends on the zinc status of the cells, It helps to balance zinc levels between the cytosol and the secretory pathway, It transports zinc into the secretory pathway in a zinc-adequate environment and in a high zinc medium, In high zinc medium, transport of zinc into the secretory pathway is a way to eliminate zinc from the cytosol, Under low cytosolic zinc conditions, it removes zinc from the secretory pathway and acts as zinc importer that helps to alleviate ER stress

Belongs to the ZIP transporter (TC 2,A,5) family, KE4/Catsup subfamily


This is RNA-binding protein SGN1 protein, from Baker's yeast, contains 250 amino acids, is soluble, locates in Cytoplasm.

mRNA-binding protein that may play a role in modulating the expression of cytoplasmic mRNA


This is Sexual differentiation process protein isp4 protein, from Fission yeast, contains 785 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Belongs to the oligopeptide OPT transporter family


This is Tetratricopeptide repeat-containing protein trd-1 protein, from Caenorhabditis elegans, contains 771 amino acids, is soluble, locates in Cytoplasm.

Developmental protein required for cell fate determination in both the germline and seam cells of the developing epidermis, Specifically, involved in sex determination and may function in parallel or downstream of other sex determination factors, including tra-2 and fem-3, to promote oogenesis in its role in the regulation of the switch from spermatogenesis to oogenesis in the gonads, Also implicated in the mitosis to meiosis switch in distal tip cells


This is Prosialokinin protein, from Yellowfever mosquito, contains 85 amino acids, is soluble, locates in Extracellular.

Vasodilatory peptide, May activate macrophages at the site of feeding


This is Mitochondrial DnaJ homolog 2 protein, from Baker's yeast, contains 146 amino acids, is membrane-bound, locates in Mitochondrion.

Plays a role in mitochondrial biogenesis and protein folding, Participates in the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner, probably by stimulating activity of mtHSP70 (SSC1)


This is Probable electron transfer flavoprotein subunit beta protein, from Baker's yeast, contains 261 amino acids, is soluble, locates in Mitochondrion.

The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase, It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)

Belongs to the ETF beta-subunit/FixA family


This is Protein FMP32, mitochondrial protein, from Baker's yeast, contains 207 amino acids, is membrane-bound, locates in Mitochondrion.


This is Inhibitor of glycogen debranching 1 protein, from Baker's yeast, contains 195 amino acids, is soluble, locates in Cytoplasm.

Acts as an inhibitor of GDB1, enhancing the ability of cells to store glucose as glycogen


This is Elongation factor 1-alpha protein, from Common tobacco, contains 447 amino acids, is soluble, locates in Cytoplasm.

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis

Belongs to the TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, EF-Tu/EF-1A subfamily


This is Sporulation-specific protein 74 protein, from Baker's yeast, contains 413 amino acids, is soluble, locates in Cytoplasm.

Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation, Probable component of a core structural unit of the scaffold that initiates synthesis of the prospore membrane


This is Mediator of RNA polymerase II transcription subunit 10 protein, from Caenorhabditis elegans, contains 173 amino acids, locates in Nucleus.

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes, Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery, Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity), Required for germ cell development and for transcriptional activation of certain stage-specific inducible promoters

Belongs to the Mediator complex subunit 10 family


This is Alpha-toxin Ts5 protein, from Brazilian scorpion, contains 64 amino acids, is soluble, locates in Extracellular.

Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission, By extending the depolarized period it indirectly affects beta-cell voltage-dependent potassium channels, thus increasing potassium permeability

Belongs to the long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family, Alpha subfamily


This is Autophagy-related protein 36 protein, from Baker's yeast, contains 293 amino acids, locates in Peroxisome.

Required for autophagic breakdown of peroxisomes, called pexophagy, through linking peroxisomes to the autophagy apparatus, Involved in regulation of the glyoxylate cycle


This is MIOREX complex component 5 protein, from Baker's yeast, contains 382 amino acids, locates in Mitochondrion.

Component of MIOREX complexes, large expressome-like assemblies of ribosomes with factors involved in all the steps of post-transcriptional gene expression


This is Altered inheritance of mitochondria protein 23, mitochondrial protein, from Baker's yeast, contains 356 amino acids, locates in Mitochondrion.


This is MIOREX complex component 12 protein, from Baker's yeast, contains 519 amino acids, locates in Mitochondrion.


This is Translation machinery-associated protein 22 protein, from Baker's yeast, contains 198 amino acids, is soluble, locates in Cytoplasm.


This is Altered inheritance of mitochondria protein 24, mitochondrial protein, from Baker's yeast, contains 394 amino acids, locates in Mitochondrion.


This is Altered inheritance rate of mitochondria protein 25 protein, from Baker's yeast, contains 327 amino acids, locates in Mitochondrion.

Belongs to the phospholipid scramblase family


This is Small ribosomal subunit protein mS42 protein, from Baker's yeast, contains 266 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mS42 family


This is Protein-lysine N-methyltransferase EFM3 protein, from Baker's yeast, contains 339 amino acids, is soluble, locates in Cytoplasm.

S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono-, di- and trimethylates elongation factor 2 (EFT1/EFT2) at 'Lys-509'

Belongs to the class I-like SAM-binding methyltransferase superfamily, EEF2KMT family


This is Xanthine phosphoribosyltransferase 1 protein, from Baker's yeast, contains 209 amino acids, is soluble, locates in Cytoplasm.

May act as a xanthine phosphoribosyltransferase involved in the synthesis of purine nucleotides, Such activity is however unclear in vivo


This is Protein SGM1 protein, from Baker's yeast, contains 707 amino acids, locates in Golgi apparatus.

Required for normal growth rate on galactose and mannose


This is Putative nitronate monooxygenase protein, from Baker's yeast, contains 404 amino acids, is soluble, locates in Cytoplasm.

Catalyzes the oxidation of alkyl nitronates to produce the corresponding carbonyl compounds and nitrites

Belongs to the nitronate monooxygenase family, NMO class I subfamily


This is Alpha-latrotoxin-associated low molecular weight protein protein, from Mediterranean black widow spider, contains 88 amino acids, is soluble, locates in Extracellular.

May increase the toxicity of alpha-latrotoxin and/or other venom components, Is non-toxic to mice and to the cockroach Periplaneta americana

Belongs to the arthropod CHH/MIH/GIH/VIH hormone family


This is Transthyretin protein, from Gray short-tailed opossum, contains 149 amino acids, is soluble, locates in Extracellular.

Thyroid hormone-binding protein, Probably transports thyroxine from the bloodstream to the brain


This is Transthyretin protein, from Australian sugar glider, contains 149 amino acids, is soluble, locates in Extracellular.


This is Mitochondrial translation factor ATP22 protein, from Baker's yeast, contains 684 amino acids, is membrane-bound, locates in Mitochondrion.

Translation factor specific for subunit 6 of the mitochondrial ATPase, Required for assembly of the CF(0) component of the ATPase


This is 3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic protein, from Mouse-ear cress, contains 473 amino acids, is soluble, locates in Plastid.

Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP, Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids (By similarity)


This is 1-Cys peroxiredoxin PER1 protein, from Barley, contains 218 amino acids, locates in Nucleus.

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (By similarity), Seems to contribute to the inhibition of germination during stress (By similarity)

Belongs to the peroxiredoxin family, Prx6 subfamily


This is Vacuolar protein sorting-associated protein 73 protein, from Baker's yeast, contains 486 amino acids, is membrane-bound, locates in Mitochondrion.

May be involved in vacuolar protein sorting

Belongs to the major facilitator superfamily, Sugar transporter (TC 2,A,1,1) family


This is Protein-lysine N-methyltransferase EFM5 protein, from Baker's yeast, contains 248 amino acids, is soluble, locates in Cytoplasm.

S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha (TEF1 and TEF2) at 'Lys-79' (PubMed:25446118), Required for replication of Brome mosaic virus (BMV) (PubMed:14671320)

Belongs to the class I-like SAM-binding methyltransferase superfamily, EFM5 family


This is Peroxisomal membrane protein PEX31 protein, from Baker's yeast, contains 462 amino acids, is membrane-bound, locates in Peroxisome.

Belongs to the PEX28-32 family, PEX30/31 subfamily


This is Small ribosomal subunit protein mS45 protein, from Baker's yeast, contains 345 amino acids, locates in Mitochondrion.

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain, The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane

Belongs to the mitochondrion-specific ribosomal protein mS45 family


This is N-acetyltransferase SLI1 protein, from Baker's yeast, contains 468 amino acids, locates in Endoplasmic reticulum.

Confers resistance to the sphingolipid biosynthesis inhibitor drug myriocin (ISP-1), Inactivates ISP-1 by converting it into N-acetyl-myriocin, Cooperates with YPK1 in mediating resistance to myriocin


This is Small ribosomal subunit protein mS33 protein, from Baker's yeast, contains 110 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mS33 family


This is Large ribosomal subunit protein bL9m protein, from Baker's yeast, contains 139 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bL9 family


This is Small ribosomal subunit protein uS19m protein, from Baker's yeast, contains 91 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uS19 family


This is Protein ZRG17 protein, from Baker's yeast, contains 605 amino acids, is membrane-bound, locates in Endoplasmic reticulum.


This is Plasma membrane fusion protein PRM1 protein, from Baker's yeast, contains 661 amino acids, is membrane-bound, locates in Cell membrane.

Involved in cell fusion during mating by stabilizing the plasma membrane fusion event


This is Pre-mRNA-splicing factor CWC25 protein, from Baker's yeast, contains 179 amino acids, locates in Nucleus.


This is Protein SWT21 protein, from Baker's yeast, contains 357 amino acids, locates in Nucleus.

Involved in mRNA splicing, Helps to stabilize the U1 snRNP-5' splice site interaction


This is Large ribosomal subunit protein uL22m protein, from Baker's yeast, contains 309 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uL22 family


This is Nucleolar protein 13 protein, from Baker's yeast, contains 403 amino acids, locates in Nucleus.


This is Signal transduction protein MDG1 protein, from Baker's yeast, contains 366 amino acids, is membrane-bound, locates in Cell membrane.

Involved in G-protein mediated signal transduction and in the regulation of polarized cell growth in pheromone-induced cells


This is Protein IBD2 protein, from Baker's yeast, contains 351 amino acids, is soluble, locates in Cytoplasm.

Part of a checkpoint which monitors spindle integrity and prevents premature exit from mitosis, This cell-cycle arrest depends upon inhibition of the G-protein TEM1 by the BFA1/BUB2 complex


This is Protein NSG2 protein, from Baker's yeast, contains 299 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Stabilizes the HMG-CoA reductase HMG2 by preventing its HRD1-dependent degradation, Binds directly to the sterol-sensing domain (SSD)-containing transmembrane region of HMG2, promoting its folding to protect it from degradation


This is Protein FYV6 protein, from Baker's yeast, contains 173 amino acids, locates in Nucleus.

Involved in telomere length regulation and required for survival upon exposure to K1 killer toxin, Promotes fully efficient non-homologous end-joining (NHEJ) by a mechanism activated in postdiauxic/stationary phase


This is Uncharacterized transporter ESBP6 protein, from Baker's yeast, contains 673 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Belongs to the major facilitator superfamily, Monocarboxylate porter (TC 2,A,1,13) family


This is Small ribosomal subunit protein uS13m protein, from Baker's yeast, contains 143 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uS13 family


This is Tyrosine-protein phosphatase-like protein OCA2 protein, from Baker's yeast, contains 197 amino acids, is soluble, locates in Cytoplasm.

Required for normal growth in the presence of linoleic acid hydroperoxide (LoaOOH)

Belongs to the protein-tyrosine phosphatase family


This is Protein-lysine N-methyltransferase EFM6 protein, from Baker's yeast, contains 246 amino acids, is soluble, locates in Cytoplasm.

S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha (TEF1 and TEF2) at 'Lys-390'

Belongs to the class I-like SAM-binding methyltransferase superfamily, METTL21 family, EFM6 subfamily


This is Mu-diguetoxin-Dc1b protein, from Desert bush spider, contains 58 amino acids, is soluble, locates in Extracellular.

Acts by delaying the inactivation of presynaptic voltage-sensitive sodium channels (Nav), Acts against insects and cause a progressive spastic paralysis

Belongs to the neurotoxin 26 (DTX) family


This is Anterior gradient protein 2 protein, from African clawed frog, contains 185 amino acids, is soluble, locates in Extracellular.

Involved in cement gland formation; probably specifies dorsal ectoderm to acquire an anterior fate such as cement gland and forebrain, Signals via the FGF pathway


This is Plastocyanin protein, from Sea lettuce, contains 98 amino acids, is membrane-bound, locates in Plastid.

Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I (By similarity), Has antiviral activity against Potato virus Y (strain N) (Ref,1)


This is Probable translation initiation factor eIF-2B subunit gamma protein, from Fission yeast, contains 458 amino acids, is soluble, locates in Cytoplasm.

Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP

Belongs to the eIF-2B gamma/epsilon subunits family


This is Protoporphyrinogen oxidase protein, from Bovine, contains 477 amino acids, is membrane-bound, locates in Mitochondrion.

Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX

Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family, Protoporphyrinogen oxidase subfamily


This is Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform protein, from Rat, contains 453 amino acids, is soluble, locates in Cytoplasm.

B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit, The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis, During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors, Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity)

Belongs to the phosphatase 2A regulatory subunit B family


This is Ladinin-1 protein, from Mouse, contains 528 amino acids, is soluble, locates in Extracellular.

Anchoring filament protein which is a component of the basement membrane zone


This is Cobrotoxin-b protein, from Monocled cobra, contains 61 amino acids, is soluble, locates in Extracellular.

Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site, Binds to the nicotinic acetylcholine receptor

Belongs to the snake three-finger toxin family, Short-chain subfamily, Type I alpha-neurotoxin sub-subfamily


This is Potassium channel toxin gamma-KTx 3.1 protein, from Mexican scorpion, contains 43 amino acids, is soluble, locates in Extracellular.

Blocks Kv11/ERG potassium channels (tested in MMQ lactotroph cells that contain the three ERG channels: rKv11,1/KCNH2/ERG1, rKv11,2/KCNH6/ERG2 and rKv11,3/KCNH7/ERG3), This toxin can be used to distinguish slow deactivating components (ERGS) from fast deactivating components (ERGF) currents, since it specifically blocks ERGS

Belongs to the ergtoxin family, Gamma-KTx 3 subfamily


This is Potassium channel toxin gamma-KTx 4.12 protein, from Arizona bark scorpion, contains 43 amino acids, is soluble, locates in Extracellular.

Reversibly blocks Kv11/ERG potassium channels, Is less toxic than ergtoxin (AC Q86QT3)

Belongs to the ergtoxin family, Gamma-KTx 4 subfamily


This is Muscarinic m1-toxin2 protein, from Eastern green mamba, contains 65 amino acids, is soluble, locates in Extracellular.

Binds irreversibly and specifically to M1 (CHRM1) muscarinic acetylcholine receptors, blocking further binding of antagonists and preventing the action of agonists

Belongs to the snake three-finger toxin family, Short-chain subfamily, Aminergic toxin sub-subfamily


This is DNA-directed RNA polymerase subunit alpha, chloroplastic protein, from Spreading-leaved earth moss, contains 450 amino acids, locates in Plastid.

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

Belongs to the RNA polymerase alpha chain family


This is Cobrotoxin protein, from Monocled cobra, contains 83 amino acids, is soluble, locates in Extracellular.

Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission


This is Neurotoxin 5 protein, from Malayan spitting cobra, contains 61 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 1 protein, from Philippine cobra, contains 61 amino acids, is soluble, locates in Extracellular.


This is Keratinocyte differentiation-associated protein protein, from Human, contains 99 amino acids, is soluble, locates in Extracellular.

May act as a soluble regulator of keratinocyte differentiation, May play an important role in embryonic skin morphogenesis


This is Protein yippee-like 3 protein, from Human, contains 119 amino acids, locates in Nucleus.

Involved in proliferation and apoptosis in myeloid precursor cells


This is Pelamitoxin a protein, from Yellow-bellied sea snake, contains 60 amino acids, is soluble, locates in Extracellular.


This is F-box only protein 40 protein, from Mouse, contains 710 amino acids, has 1 TRAF-type Zinc finger, is soluble, locates in Cytoplasm.

TRAF-type

Probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that may function in myogenesis


This is Snake venom vascular endothelial growth factor toxin TfsvVEGF protein, from Habu, contains 146 amino acids, is soluble, locates in Extracellular.

Snake venom VEGFs may contribute to venom dispersion and prey subjugation by inducing vascular permeability and hypotension, This protein strongly increases vascular permeability, and weakly stimulates angiogenesis, Interacts with VEGF receptor-1 (FLT1) with a high affinity, whereas it binds to VEGF receptor-2 (KDR) with a low affinity, Stimulates autophosphorylation of VEGF receptor-1 (VEGFR-1/FLT1), and VEGF receptor-2 (VEGFR-2/KDR)

Belongs to the PDGF/VEGF growth factor family, Snake venom VEGF subfamily


This is Ferredoxin protein, from Downy thornapple, contains 97 amino acids, locates in Plastid.

Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions

Belongs to the 2Fe2S plant-type ferredoxin family


This is Ferredoxin protein, from Devil's trumpet, contains 97 amino acids, locates in Plastid.


This is Ferredoxin protein, from Oak leaved angel's trumpet, contains 97 amino acids, locates in Plastid.


This is Short neurotoxin 1 protein, from Stokes's sea snake, contains 60 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 1 protein, from Beaked sea snake, contains 60 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 1 protein, from Hardwick's spine-bellied seasnake, contains 81 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 1 protein, from Banded Egyptian cobra, contains 61 amino acids, is soluble, locates in Extracellular.

Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site, Binds to the muscular nicotinic acetylcholine receptor


This is Short neurotoxin 1 protein, from Egyptian cobra, contains 61 amino acids, is soluble, locates in Extracellular.


This is Short neurotoxin 1 protein, from Cape cobra, contains 61 amino acids, is soluble, locates in Extracellular.


This is DNA-directed RNA polymerase 3A, chloroplastic protein, from Common tobacco, contains 977 amino acids, locates in Plastid.

Belongs to the phage and mitochondrial RNA polymerase family


This is rRNA methyltransferase 2, mitochondrial protein, from Fission yeast, contains 218 amino acids, locates in Mitochondrion.

S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of the 2'-O-methyluridine corresponding to position 2791 in S,cerevisiae 21S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA

Belongs to the class I-like SAM-binding methyltransferase superfamily, RNA methyltransferase RlmE family


This is Alpha-L-arabinofuranosidase axhA protein, from Aspergillus niger, contains 332 amino acids, is soluble, locates in Extracellular.

Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose, Releases L-arabinose from arabinoxylan

Belongs to the glycosyl hydrolase 62 family


This is Probable alpha-L-arabinofuranosidase axhA protein, from Aspergillus tubingensis, contains 332 amino acids, is soluble, locates in Extracellular.

Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose, Releases L-arabinose from arabinoxylan (By similarity)


This is Protein transport protein sec61 subunit alpha protein, from Fission yeast, contains 479 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER, It is required for assembly of membrane and secretory proteins and is essential for cell growth, It interacts with other membrane proteins required for protein translocation, Upon binding to sec62/63 complex, secretory precursor polypeptides may engage sec61 to begin membrane penetration event, A cycle of assembly and disassembly of sec62/63 from sec61 may govern the activity of the translocase (By similarity)


This is Non-specific lipid-transfer protein P3 protein, from Grape, contains 91 amino acids, is soluble, locates in Extracellular.

Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes, May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues


This is Light-induced protein, chloroplastic protein, from Potato, contains 326 amino acids, is membrane-bound, locates in Plastid.

Required for normal plant growth, May be both photoprotective and play an ancillary role in photosynthesis, May structurally stabilize thylakoids during osmotic and oxidative stress


This is Three-finger toxin Mnn I protein, from Central American coral snake, contains 60 amino acids, is soluble, locates in Extracellular.


This is Protein-L-isoaspartate(D-aspartate) O-methyltransferase protein, from Pig, contains 227 amino acids, is soluble, locates in Cytoplasm.

Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in aging peptides and proteins (By similarity), Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin C-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein (By similarity)

Belongs to the methyltransferase superfamily, L-isoaspartyl/D-aspartyl protein methyltransferase family


This is Long neurotoxin OH-5 protein, from King cobra, contains 72 amino acids, is soluble, locates in Extracellular.

Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission

Belongs to the snake three-finger toxin family, Long-chain subfamily, Type II alpha-neurotoxin sub-subfamily


This is Snaclec echicetin subunit alpha protein, from Saw-scaled viper, contains 133 amino acids, is soluble, locates in Extracellular.

Echicetin itself inhibits aggregation of washed platelets induced by vWF, thrombin or alboaggregin-A (PubMed:8481512, PubMed:11290595), However, when complexed with the pentameric plasma immunoglobulin Mkappa (IgMkappa), echicetin binds specifically to GPIb and activates platelets, This is caused by P-selectin expression and activation of alpha-IIb/beta-3 as well as tyrosine phosphorylation of several signal transduction molecules, including p53/56(LYN), p64, p72(SYK), p70 to p90, and p120 (PubMed:11290595), In vivo, it induces thrombocytopenia when injected into mice (PubMed:8481512), probably accounting of activation of platelets rather than inhibition (PubMed:11290595)


This is Muscarinic toxin 1 protein, from Eastern green mamba, contains 66 amino acids, is soluble, locates in Extracellular.

Shows a non-competitive interaction with adrenergic and muscarinic receptors, Binds to alpha-2b (ADRA2B) (IC(50)=2,3 nM), alpha-1a (ADRA1A), alpha-1b (ADRA1B), and alpha-2c (ADRA2C) adrenergic receptors, Reversibly binds to M1 (CHRM1) muscarinic acetylcholine receptors, probably by interacting with the orthosteric site (PubMed:7778123, PubMed:12488533, PubMed:24793485), Also reveals a slightly weaker effect at M3 (CHRM3) and M4 (CHRM4) receptors (PubMed:7778123, PubMed:12488533, PubMed:24793485), The order of potency is ADRA2B>>CHRM1>ADRA1A>ADRA1B>ADRA2C/CHRM4 (PubMed:24793485)


This is Snaclec alboaggregin-A subunit alpha protein, from White-lipped pit viper, contains 131 amino acids, is soluble, locates in Extracellular.

Potent platelet activator that aggregates platelets via both GPIbalpha (GP1BA) and GPVI (GP6), Induces a tyrosine phosphorylation profile in platelets that resembles this produced by collagen, involving the time dependent tyrosine phosphorylation of Fc receptor gamma chain (FCGR1A), phospholipase Cgamma2 (PLCG2), and LAT


This is Snaclec alboaggregin-A subunit alpha' protein, from White-lipped pit viper, contains 134 amino acids, is soluble, locates in Extracellular.


This is Snaclec alboaggregin-A subunit beta protein, from White-lipped pit viper, contains 125 amino acids, is soluble, locates in Extracellular.


This is Snaclec alboaggregin-A subunit beta' protein, from White-lipped pit viper, contains 123 amino acids, is soluble, locates in Extracellular.


This is Snaclec CHH-B subunit alpha protein, from Timber rattlesnake, contains 127 amino acids, is soluble, locates in Extracellular.

Binds to the subunit GPIbalpha (GP1BA) of the platelet GPIb/V/IX receptor system, It inhibits ristocetin- and vWF-induced platelet aggregation in platelet-rich plasma by inhibiting the binding of vWF to GPIbalpha


This is Thylakoid lumenal 17.4 kDa protein, chloroplastic protein, from Mouse-ear cress, contains 236 amino acids, locates in Plastid.


This is Bucandin protein, from Malayan krait, contains 63 amino acids, is soluble, locates in Extracellular.

This toxin is described as enhancing presynaptic acetylcholine release, but neither experimental results, nor references to other sources are available

Belongs to the snake three-finger toxin family, Ancestral subfamily, Orphan group XIX sub-subfamily


This is U7-ctenitoxin-Pn1a protein, from Brazilian armed spider, contains 84 amino acids, is soluble, locates in Extracellular.

Antagonist of L-type calcium channels (Cav1/CACNA1), Causes paralysis in the posterior limbs and gradual decreases in movement and aggression during 24 hours at dose levels of 5 ug per mouse

Belongs to the neurotoxin 02 (plectoxin) family


This is Snaclec echicetin subunit beta protein, from Saw-scaled viper, contains 123 amino acids, is soluble, locates in Extracellular.


This is Defensin-like peptide 1 protein, from Duckbill platypus, contains 66 amino acids, is soluble, locates in Extracellular.

Does not show antimicrobial, myotoxic, hemolytic and cell-promoting activities


This is Large ribosomal subunit protein cL38 protein, from Spinach, contains 116 amino acids, locates in Plastid.

Component of the chloroplast ribosome (chloro-ribosome), a dedicated translation machinery responsible for the synthesis of chloroplast genome-encoded proteins, including proteins of the transcription and translation machinery and components of the photosynthetic apparatus

Belongs to the chloroplast-specific ribosomal protein cL38 family


This is Muscarinic toxin-like protein 1 protein, from Monocled cobra, contains 65 amino acids, is soluble, locates in Extracellular.

Binds weakly to the muscarinic acetylcholine receptor (CHRM)

Belongs to the snake three-finger toxin family, Short-chain subfamily, Type C muscarinic toxin sub-subfamily


This is Cobrotoxin II protein, from Monocled cobra, contains 62 amino acids, is soluble, locates in Extracellular.

Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission


This is Small ribosomal subunit protein bS16m protein, from Bovine, contains 135 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bS16 family


This is Small ribosomal subunit protein uS17m protein, from Bovine, contains 130 amino acids, locates in Mitochondrion.

Belongs to the universal ribosomal protein uS17 family


This is Small ribosomal subunit protein bS18m protein, from Bovine, contains 143 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bS18 family


This is Small ribosomal subunit protein uS2m protein, from Bovine, contains 293 amino acids, locates in Mitochondrion.

Required for mitoribosome formation and stability, and mitochondrial translation

Belongs to the universal ribosomal protein uS2 family


This is Small ribosomal subunit protein mS31 protein, from Bovine, contains 386 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mS31 family


This is Large ribosomal subunit protein mL42 protein, from Bovine, contains 142 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mL42 family


This is Small ribosomal subunit protein bS1m protein, from Bovine, contains 189 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bS1 family


This is Small ribosomal subunit protein mS34 protein, from Bovine, contains 218 amino acids, locates in Mitochondrion.

Required for mitochondrial translation, plays a role in maintaining the stability of the small ribosomal subunit and the 12S rRNA that are required for mitoribosome formation

Belongs to the mitochondrion-specific ribosomal protein mS34 family


This is Small ribosomal subunit protein bS6m protein, from Bovine, contains 124 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bS6 family


This is Serine beta-lactamase-like protein LACTB, mitochondrial protein, from Bovine, contains 556 amino acids, locates in Mitochondrion.

Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism, Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism, It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein


This is Sperm protamine P2 protein, from Purple dye murex, contains 58 amino acids, locates in Nucleus.

Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis, They compact sperm DNA into a highly condensed, stable and inactive complex


This is Sperm protamine P3 protein, from Purple dye murex, contains 54 amino acids, locates in Nucleus.


This is Ohanin protein, from King cobra, contains 190 amino acids, is soluble, locates in Extracellular.

Neurotoxin that produces dose-dependent hypolocomotion and hyperalgesia in mice, May directly act on the central nervous system, as it is 6500-fold more potent when administered intracerebroventricularly than intraperitoneal


This is Mating pheromone En-2 protein, from Ciliate, contains 60 amino acids, is soluble, locates in Extracellular.

Mating ciliate pheromones (or gamones) are diffusible extracellular communication signals that distinguish different intraspecific classes of cells commonly referred to as 'mating types', They prepare the latter for conjugation by changing their cell surface properties


This is NADH-cytochrome b5 reductase-like protein protein, from Mouse-ear cress, contains 328 amino acids, locates in Mitochondrion.

Desaturation and elongation of fatty acids

Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family


This is Bucain protein, from Malayan krait, contains 65 amino acids, is soluble, locates in Extracellular.

Belongs to the snake three-finger toxin family, Short-chain subfamily, Orphan group III sub-subfamily


This is Virescein protein, from Tobacco budworm moth, contains 41 amino acids, is soluble, locates in Extracellular.

Has antibacterial activity against Gram-positive and Gram-negative bacteria


This is Alpha-toxin Tf4 protein, from Central Brazilian scorpion, contains 62 amino acids, is soluble, locates in Extracellular.

Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission (PubMed:12782073), This toxin is toxic to frogs but non-toxic to insect larvae (T,molitor), mammals (rats) and crustaceans (crabs) at the doses assayed (PubMed:12782073)

Belongs to the long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family, Alpha subfamily


This is Mating pheromone En-1 protein, from Ciliate, contains 52 amino acids, is soluble, locates in Extracellular.


This is Tryptophyllin-1 protein, from Giant Mexican leaf frog, contains 62 amino acids, is soluble, locates in Extracellular.

Myoactive, Has selective relaxing activity on vascular smooth muscle

Belongs to the frog skin active peptide (FSAP) family, Tryptophillin subfamily


This is Alpha-colubritoxin protein, from Radiated ratsnake, contains 77 amino acids, is soluble, locates in Extracellular.

Potent postsynaptic neurotoxin, Displays readily reversible competitive antagonism at the nicotinic acetylcholine receptor (nAChR)

Belongs to the snake three-finger toxin family, Ancestral subfamily, Boigatoxin sub-subfamily


This is Pregnancy-associated glycoprotein 6 protein, from Sheep, contains 380 amino acids, is soluble, locates in Extracellular.


This is Pregnancy-associated glycoprotein 4 protein, from Sheep, contains 380 amino acids, is soluble, locates in Extracellular.


This is Ferredoxin protein, from Angel's trumpet tree, contains 97 amino acids, locates in Plastid.

Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions

Belongs to the 2Fe2S plant-type ferredoxin family


This is Ferredoxin protein, from Chinese wolfberry, contains 97 amino acids, locates in Plastid.


This is Ferredoxin protein, from Japanese lantern, contains 97 amino acids, locates in Plastid.


This is Ferredoxin protein, from Japanese belladonna, contains 97 amino acids, locates in Plastid.


This is Ferredoxin protein, from Common tobacco, contains 97 amino acids, locates in Plastid.


This is Ferredoxin protein, from Red pepper, contains 97 amino acids, locates in Plastid.


This is Mu-hexatoxin-Mg2a protein, from Japanese funnel web spider, contains 46 amino acids, is soluble, locates in Extracellular.

Competes for binding at site 3 of the insect voltage-gated sodium channel (Nav) (PubMed:12860384), Insecticidal neurotoxin (PubMed:12860384, PubMed:29247580), Causes temporary paralysis to lepidopteran larvae (10,3 nmol/g) or to crickets (doses from 0,93 to 119 ug/g) (PubMed:12860384, PubMed:29247580), Is not toxic to mice when injected intracranially (high doses) (PubMed:12860384, PubMed:29247580)

Belongs to the neurotoxin 02 (plectoxin) family, 02 (plectoxin) subfamily


This is Proteinase inhibitor PSKP-2 protein, from Sauvage's leaf frog, contains 58 amino acids, is soluble, locates in Extracellular.

May have a role in mucosal defense against microbes by interacting directly with their membranes


This is Ferredoxin protein, from Black nightshade, contains 97 amino acids, locates in Plastid.


This is Ferredoxin protein, from Lyreleaf nightshade, contains 97 amino acids, locates in Plastid.


This is Ferredoxin protein, from Indian nightshade, contains 97 amino acids, locates in Plastid.


This is Ferredoxin protein, from Cyphomandra abutiloides, contains 97 amino acids, locates in Plastid.


This is Delta-actinopoditoxin-Mb1a protein, from Eastern mouse spider, contains 42 amino acids, is soluble, locates in Extracellular.

Lethal neurotoxin active on both vertebrates and insects, Slows the inactivation of vertebrate tetrodotoxin-sensitive voltage-gated sodium channels (Nav) and most likely insect sodium channels presumably by binding to site 3 of the channel, Effects are an increase in resting tension, a muscle fasciculation and a decrease in indirect twitch tension, It fails to affect tetrodotoxin-resistant sodium currents

Belongs to the neurotoxin 06 (delta-actx) family


This is Disintegrin schistatin protein, from Saw-scaled viper, contains 64 amino acids, is soluble, locates in Extracellular.

May bind to both alpha-IIb/beta-3 (ITGA2B/ITGB3) and alpha-V/beta-3 (ITGAV/ITGB3) integrins, and may inhibit platelet aggregation

Belongs to the disintegrin family, Dimeric disintegrin subfamily


This is Defensin-B protein, from Cupreous chafer beetle, contains 43 amino acids, is soluble, locates in Extracellular.

Antibacterial protein, Strong activity against the Gram-positive bacteria M,luteus, B,megaterium and S,aureus, Reduced activity against Gram-positive bacterium B,subtilis and weak activity against Gram-negative bacterium X,japonicus, No detectable activity against the Gram-negative bacteria E,asbriae, E,coli, P,aeruginosa and S,marcescens

Belongs to the invertebrate defensin family, Type 1 subfamily


This is Defensin-A protein, from Cupreous chafer beetle, contains 43 amino acids, is soluble, locates in Extracellular.


This is Inorganic pyrophosphatase protein, from Yeast, contains 288 amino acids, is soluble, locates in Cytoplasm.


This is Malate dehydrogenase, cytoplasmic protein, from Yeast, contains 337 amino acids, is soluble, locates in Cytoplasm.

Belongs to the LDH/MDH superfamily, MDH type 1 family


This is U9-ctenitoxin-Pr1a protein, from Brazilian Amazonian armed spider, contains 64 amino acids, is soluble, locates in Extracellular.


This is U1-ctenitoxin-Pk1a protein, from Brazilian wandering spider, contains 45 amino acids, is soluble, locates in Extracellular.

Neurotoxin, Causes rapid general flaccid paralysis and death in mice at dose levels of 5 ug per mouse

Belongs to the neurotoxin 02 (plectoxin) family, 01 (Tx3) subfamily


This is U8-ctenitoxin-Pr1a protein, from Brazilian Amazonian armed spider, contains 58 amino acids, is soluble, locates in Extracellular.

No toxic effects on mice at dose levels of 5 ug per mouse, May be toxic to insects

Belongs to the neurotoxin 09 (Tx3-6) family


This is U8-ctenitoxin-Pk1a protein, from Brazilian wandering spider, contains 58 amino acids, is soluble, locates in Extracellular.


This is Delta-ctenitoxin-Pr2d protein, from Brazilian Amazonian armed spider, contains 47 amino acids, is soluble, locates in Extracellular.

Blocks voltage-gated sodium channels (Nav), Causes rapid general spastic paralysis and death when injected in mice at dose levels of less than 2 ug per mouse

Belongs to the neurotoxin 03 (Tx2) family, 06 subfamily


This is U2-ctenitoxin-Pk1a protein, from Brazilian wandering spider, contains 50 amino acids, is soluble, locates in Extracellular.

Insecticidal neurotoxin that reversibly inhibits the N-methyl-D-aspartate (NMDA)-subtype of ionotropic glutamate receptor (GRIN) and inhibits inactivation of insect sodium channels (Nav), In vivo, is highly toxic to insects

Belongs to the neurotoxin 03 (Tx2) family, 05 subfamily


This is Vascular endothelial growth factor A protein, from Gaboon adder, contains 191 amino acids, is soluble, locates in Extracellular.

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth, Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels, Binds to heparan sulfate and heparin

Belongs to the PDGF/VEGF growth factor family


This is U2-ctenitoxin-Pr1a protein, from Brazilian Amazonian armed spider, contains 40 amino acids, is soluble, locates in Extracellular.