This is DNA replication checkpoint protein tel2 protein, from Fission yeast, contains 868 amino acids, is soluble, locates in Cytoplasm.

Component of the TORC1 and TORC2 complexes required for the regulation of the cellular respons to changes in available nutrients, Required for normal entry into S phase, Regulates activation of the DNA replication checkpoint, Required for efficient phosphorylation of mrc1, which is essential for the activation of cds1 kinase, Also plays an important role in genome stability


This is Intracellular hyphae protein 1 protein, from Bean anthracnose fungus, contains 230 amino acids, is soluble, locates in Extracellular.

May have roles in host-pathogen interaction, including establishment and maintenance of biotrophy, prevention of host recognition of the fungus and a barrier to host defense molecules


This is Cys-Gly metallodipeptidase dug1 protein, from Fission yeast, contains 476 amino acids, is soluble, locates in Cytoplasm.

Catalytic component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond, Has a Gly-Cys dipeptidase activity


This is Structure-specific endonuclease subunit slx4 protein, from Fission yeast, contains 419 amino acids, locates in Nucleus.

Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination, Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA, Has a preference for stem-loop (SL) and splayed arm Y structures, Introduces a single-strand cut in duplex DNA on the 3' side of a double-strand/single-strand junction with respect to the single-strand moving 3' to 5' away from the junction, Plays a critical role in maintaining the integrity of the ribosomal DNA (rDNA) loci, where it has a role in re-starting stalled replication forks, The complex initiates homologous recombination (HR) events, used to maintain rDNA copy number, in the rDNA repeats that are processed by a mechanism that requires rad22, but not rhp51, Has Holliday junction resolvase activity in vitro, Slx4 is required for efficient processing of DNA substrates


This is [Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial protein, from Fission yeast, contains 425 amino acids, is soluble, locates in Mitochondrion.

Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism

Belongs to the PDK/BCKDK protein kinase family


This is Meiotically up-regulated gene 172 protein protein, from Fission yeast, contains 331 amino acids, is soluble, locates in Cytoplasm.


This is SWR complex protein 2 protein, from Fission yeast, contains 316 amino acids, locates in Nucleus.

Participates in the catalytic exchange of histone H2A for the H2A variant pht1, an euchromatin-specific factor, leading to chromatin remodeling and changes in transcription of targeted genes


This is U1 small nuclear ribonucleoprotein C protein, from Fission yeast, contains 182 amino acids, has 1 Matrin-type Zinc finger, locates in Nucleus.

Matrin-type

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome, usp103/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing, The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA, Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region

Belongs to the U1 small nuclear ribonucleoprotein C family


This is H/ACA ribonucleoprotein complex subunit nhp2 protein, from Fission yeast, contains 154 amino acids, locates in Nucleus.

Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis (PubMed:10502409), This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 (By similarity), Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity), The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs (By similarity), The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA (By similarity), Directly binds H/ACA snoRNAs (By similarity)

Belongs to the eukaryotic ribosomal protein eL8 family


This is DNA-directed RNA polymerase I subunit rpa14 protein, from Fission yeast, contains 147 amino acids, locates in Nucleus.

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates, Component of RNA polymerase I which synthesizes ribosomal RNA precursors, A14 seems to play a role in the stability of Pol I subunit A43 and association of rrn3 to Pol I


This is F-box/WD repeat-containing protein pof10 protein, from Fission yeast, contains 662 amino acids, is soluble, locates in Cytoplasm.

Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation


This is RNA polymerase II elongation factor ell1 protein, from Fission yeast, contains 533 amino acids, locates in Nucleus.

Activates transcription elongation by RNA polymerase II and pyrophosphorolysis as a complex with eaf1, Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA


This is Protein transport protein SEC61 subunit alpha protein, from Yeast, contains 479 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER, It is required for assembly of membrane and secretory proteins and is essential for cell growth, It interacts with other membrane proteins required for protein translocation, Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event, A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity)


This is Forkhead box protein D5-A protein, from African clawed frog, contains 352 amino acids, locates in Nucleus.

Transcriptional repressor with a role in dorsal axis formation and neural plate expansion; maintains an undifferentiated neural ectoderm after neural induction


This is Mitochondrial fission regulator 1 protein, from Chicken, contains 335 amino acids, locates in Mitochondrion.

May play a role in mitochondrial aerobic respiration, May also regulate mitochondrial organization and fission


This is Prokineticin Bv8 protein, from Yellow-bellied toad, contains 96 amino acids, is soluble, locates in Extracellular.

Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia (PubMed:16299550, PubMed:20677202), Shows an EC(50) of 0,264 nM, when tested on neuroblastoma cells (SH-SY5Y) which endogenously express mainly PKR2/PROKR2 (PubMed:20677202), Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons (PubMed:16687502, PubMed:20677202), Induces a biphasic hyperalgesia to tactile and thermal stimuli after systemic injection of this protein into rat (PubMed:10422759, PubMed:12466223), The initial phase of hyperalgesia is caused by a local action on nociceptors, because intraplantar injection of this protein causes a strong and localized hyperalgesia with a similar time course to that of the initial phase of hyperalgesia seen with systemic injection, The secondary phase of hyperalgesia is not seen with local intraplantar injection and is therefore probably attributable to a central action of this protein (PubMed:16687502), At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12 (PubMed:16299550), In vivo, this protein potently stimulates the contraction of the guinea-pig gastrointestinal (GI) smooth muscle (at nanomolar concentration) (PubMed:10422759)

Belongs to the AVIT (prokineticin) family


This is Dynactin subunit 4 protein, from Rat, contains 467 amino acids, is soluble, locates in Cytoplasm.

Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules

Belongs to the dynactin subunit 4 family


This is Spermatid-specific linker histone H1-like protein protein, from Mouse, contains 170 amino acids, locates in Nucleus.

DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa


This is Activator of basal transcription 1 protein, from Mouse, contains 269 amino acids, locates in Nucleus.

Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator, Can act as a regulator of basal transcription for class II genes


This is Transmembrane protein 150A protein, from Rat, contains 271 amino acids, is membrane-bound, locates in Cell membrane.

Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, possibly by reducing the association of TTC7 (TTC7A or TTC7B) with the PI4K complex, Acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (By similarity), May also play a role in fasting-induced catabolism (PubMed:10858565)


This is Acid-sensing ion channel 5 protein, from Rat, contains 495 amino acids, is membrane-bound, locates in Cell membrane.

Cation channel that gives rise to very low constitutive currents in the absence of activation, The activated channel exhibits selectivity for sodium and lithium, and is inhibited by amiloride

Belongs to the amiloride-sensitive sodium channel (TC 1,A,6) family, ASIC5 subfamily


This is Netrin-3 protein, from Mouse, contains 580 amino acids, is soluble, locates in Extracellular.

Netrins control guidance of CNS commissural axons and peripheral motor axons


This is Heme-binding protein 1 protein, from Mouse, contains 190 amino acids, is soluble, locates in Cytoplasm.

May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound, Binds with a high affinity to one molecule of heme or porphyrins, It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities


This is Two-pore potassium channel 5 protein, from Mouse-ear cress, contains 408 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Probable voltage-independent potassium-selective tonoplast ion channel

Belongs to the two pore domain potassium channel (TC 1,A,1,7) family


This is ATP sulfurylase 4, chloroplastic protein, from Mouse-ear cress, contains 469 amino acids, is soluble, locates in Plastid.

Sulfate adenylyltransferase, Catalyzes the first step of the sulfate assimilation pathway

Belongs to the sulfate adenylyltransferase family


This is Pentatricopeptide repeat-containing protein At1g74850, chloroplastic protein, from Mouse-ear cress, contains 862 amino acids, locates in Plastid.


This is Protein LONGIFOLIA 2 protein, from Mouse-ear cress, contains 905 amino acids, is soluble, locates in Cytoplasm.

In association with LNG1, regulates leaf morphology by promoting longitudinal polar cell elongation independently of ROT3, Associates with microtubules and recruits TON1A and TON1B to the cytoskeleton through its C-terminus


This is Transcription factor MYB3 protein, from Mouse-ear cress, contains 257 amino acids, locates in Nucleus.


This is Photosynthetic NDH subunit of subcomplex B 1, chloroplastic protein, from Mouse-ear cress, contains 461 amino acids, is membrane-bound, locates in Plastid.

NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain, The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone, Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient


This is Organic cation/carnitine transporter 5 protein, from Mouse-ear cress, contains 515 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

High affinity carnitine transporter involved in the active cellular uptake of carnitine, Also transports organic cations (By similarity)

Belongs to the major facilitator (TC 2,A,1) superfamily, Organic cation transporter (TC 2,A,1,19) family


This is Probably inactive leucine-rich repeat receptor-like protein kinase IMK2 protein, from Mouse-ear cress, contains 836 amino acids, is membrane-bound, locates in Cell membrane.

Belongs to the protein kinase superfamily, Ser/Thr protein kinase family


This is Glycerol-3-phosphate dehydrogenase [NAD(+)] 1, chloroplastic protein, from Mouse-ear cress, contains 400 amino acids, locates in Plastid.

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family


This is ATP-dependent zinc metalloprotease FTSH 7, chloroplastic protein, from Mouse-ear cress, contains 802 amino acids, is membrane-bound, locates in Plastid.

Probable ATP-dependent zinc metallopeptidase

In the C-terminal section; belongs to the peptidase M41 family


This is Ribulose-phosphate 3-epimerase, cytoplasmic isoform protein, from Rice, contains 228 amino acids, is soluble, locates in Cytoplasm.

Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate

Belongs to the ribulose-phosphate 3-epimerase family


This is Hexokinase-1 protein, from Spinach, contains 498 amino acids, is membrane-bound, locates in Plastid.

Fructose and glucose phosphorylating enzyme


This is Pentatricopeptide repeat-containing protein At3g09650, chloroplastic protein, from Mouse-ear cress, contains 778 amino acids, is soluble, locates in Plastid.

Involved in the processing of polycistronic chloroplast psbB-psbT-psbH-petB-petD transcript, Could bind RNA


This is Beta-1,6-galactosyltransferase GALT29A protein, from Mouse-ear cress, contains 398 amino acids, is membrane-bound, locates in Golgi apparatus.

Galactosyltransferase involved in the biosynthesis of type II arabinogalactan, Possesses galactosyltransferase (GalT) activity in vitro, transferring galactose from UDP-galactose to a mixture of various oligosaccharides derived from arabinogalactan proteins, Forms a complex with GALT31A that can work cooperatively to enhance the activities of adding galactose residues at O6 positions to beta-1,6-galactan and beta-1,3-galactan

Belongs to the glycosyltransferase 29 family


This is Cyclin-dependent protein kinase inhibitor SMR2 protein, from Mouse-ear cress, contains 111 amino acids, locates in Nucleus.

Cyclin-dependent protein kinase (CDK) inhibitor that restricts cell proliferation and cooperates with SIM and SMR1 to promote endoreplication during leaf development (PubMed:26546445)


This is ATP-citrate synthase alpha chain protein 1 protein, from Mouse-ear cress, contains 423 amino acids, is soluble, locates in Cytoplasm.

ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, used for the elongation of fatty acids and biosynthesis of isoprenoids, flavonoids and malonated derivatives, May supply substrate to the cytosolic acetyl-CoA carboxylase, which generates the malonyl-CoA used for the synthesis of a multitude of compounds, including very long chain fatty acids and flavonoids, Required for normal growth and development and elongation of C18 fatty acids to C20 to C24 fatty acids in seeds, In contrast to all known animal ACL enzymes having a homomeric structure, plant ACLs are composed of alpha and beta chains

Belongs to the succinate/malate CoA ligase beta subunit family


This is Exosome complex exonuclease RRP44 homolog A protein, from Mouse-ear cress, contains 933 amino acids, locates in Nucleus.

Catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events, Required for 5,8S rRNA intermediate processing and the degradation of 5' external transcribed spacer (5' ETS), a maturation by-product of rRNA synthesis, Is not involved in the degradation of turnip crinkle virus (TCV) RNA and significant virus resistance (PubMed:24244451), Required for normal development of female gametophytes and early embryogenesis (PubMed:20798041, PubMed:24244451)


This is GTPase LSG1-1 protein, from Mouse-ear cress, contains 537 amino acids, is soluble, locates in Cytoplasm.

GTPase that might be redundant with LSG1-2 for ribosome biogenesis (Probable), Binds to 23S rRNA (PubMed:25319368)

Belongs to the TRAFAC class YlqF/YawG GTPase family


This is Protein DETOXIFICATION 1 protein, from Mouse-ear cress, contains 476 amino acids, is membrane-bound, locates in Cell membrane.

Efflux carrier for plant-derived alkaloids, antibiotics, heavy metal and other toxic compounds, Involved in cadmium detoxification, Requires probably a proton-motive force for the efflux

Belongs to the multi antimicrobial extrusion (MATE) (TC 2,A,66,1) family


This is Zinc finger protein ZAT2 protein, from Mouse-ear cress, contains 270 amino acids, has 3 C2H2-type Zinc finger, locates in Nucleus.

Mediates the regulation of male germ cell division by DUO1


This is 3-ketoacyl-CoA synthase 9 protein, from Mouse-ear cress, contains 512 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Involved in the elongation of C22 to C24 fatty acids, which are precursors for the biosynthesis of cuticular waxes, aliphatic suberins, and membrane lipids, including sphingolipids and phospholipids

Belongs to the thiolase-like superfamily, Chalcone/stilbene synthases family


This is Citrate synthase 3, peroxisomal protein, from Mouse-ear cress, contains 509 amino acids, locates in Peroxisome.

Peroxisomal citrate synthase required for the fatty acid respiration in seedlings, citrate being exported from peroxisomes into mitochondria during respiration of triacylglycerol (TAG), Indeed, complete respiration requires the transfer of carbon in the form of citrate from the peroxisome to the mitochondria


This is Multiprotein-bridging factor 1a protein, from Mouse-ear cress, contains 142 amino acids, locates in Nucleus.

Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators


This is Chaperone protein dnaJ A6, chloroplastic protein, from Mouse-ear cress, contains 442 amino acids, has 1 CR-type Zinc finger, locates in Plastid.

CR-type

May function together with HSC70 chaperone to assist protein folding and prevent protein aggregation during heat stress in the chloroplast


This is Cation/H(+) antiporter 21 protein, from Mouse-ear cress, contains 832 amino acids, is membrane-bound, locates in Cell membrane.

Operates as a Na(+)/H(+) antiporter that plays a role in regulation of xylem Na(+) concentration and, consequently, Na(+) accumulation in the leaf, Required for pollen tube guidance, but not for normal pollen development, May also be involved in the development or function of the female gametophyte

Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2,A,37) family, CHX (TC 2,A,37,4) subfamily


This is Double-stranded RNA-binding protein 2 protein, from Mouse-ear cress, contains 434 amino acids, is soluble, locates in Cytoplasm.

Binds double-stranded RNA, May be involved in RNA-mediated silencing


This is Transcription factor Pur-alpha 1 protein, from Mouse-ear cress, contains 296 amino acids, locates in Nucleus.

Transcription factor that specifically binds the purine-rich double-stranded telomeric repeated sequence 5'-AAACCCTAA-3' found in promoter telo boxes

Belongs to the PUR DNA-binding protein family


This is Methionine aminopeptidase 1A protein, from Mouse-ear cress, contains 398 amino acids, has 1 C6H2-type Zinc finger, is soluble, locates in Cytoplasm.

Cotranslationally removes the N-terminal methionine from nascent proteins, The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)

Belongs to the peptidase M24A family, Methionine aminopeptidase type 1 subfamily


This is Outer envelope pore protein 21, chloroplastic protein, from Garden pea, contains 177 amino acids, is membrane-bound, locates in Plastid.

Voltage-dependent rectifying anion channel that facilitates the translocation between chloroplast and cytoplasm of phosphorylated carbohydrates such as triosephosphate, 3-phosphoglycerate and inorganic phosphate (Pi) depending of ATP to triosephosphate ratio in the plastidial intermembrane space; in high triosephosphate/ATP conditions (e,g, photosynthesis), export of triosphosphate from chloroplast (outward rectifying channels), but in high ATP/triosephosphate conditions (e,g, dark phase), import of phosphosolutes (inward rectifying channels)

Belongs to the plastid outer envelope porin OEP21 (TC 1,B,29) family


This is Transcription factor MYB26 protein, from Mouse-ear cress, contains 367 amino acids, locates in Nucleus.

Probable transcription factor that regulates lignified secondary cell wall thickening of the anther endocethium, which is necessary for anther dehiscence (PubMed:12753590, PubMed:17147638, PubMed:17329564), May play a role in specifying early endothecial cell development by regulating a number of genes linked to secondary thickening such as NST1 and NST2, Acts upstream of the lignin biosynthesis pathway (PubMed:17329564)


This is Ammonium transporter 1 member 3 protein, from Mouse-ear cress, contains 498 amino acids, is membrane-bound, locates in Cell membrane.

Ammonium transporter probably involved in ammonium uptake from the soil, Contributes with AMT1-1 to the overall ammonium uptake capacity in roots under nitrogen-deficiency conditions

Belongs to the ammonia transporter channel (TC 1,A,11,2) family


This is Cytosolic endo-beta-N-acetylglucosaminidase 2 protein, from Mouse-ear cress, contains 701 amino acids, is soluble, locates in Cytoplasm.

Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core, Involved in the production of high-mannose type N-glycans during plant development and fruit maturation

Belongs to the glycosyl hydrolase 85 family


This is PHD finger protein ALFIN-LIKE 2 protein, from Mouse-ear cress, contains 246 amino acids, has 1 PHD-type Zinc finger, locates in Nucleus.

PHD-type

Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes


This is YlmG homolog protein 1-1, chloroplastic protein, from Mouse-ear cress, contains 232 amino acids, is membrane-bound, locates in Plastid.

Required for the proper distribution of nucleoids in chloroplasts, The nucleoid partitioning by YLMG1-1 may be related to chloroplast division processes


This is BTB/POZ and MATH domain-containing protein 4 protein, from Mouse-ear cress, contains 465 amino acids, is soluble, locates in Cytoplasm.

May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins


This is Protein LOW PSII ACCUMULATION 1, chloroplastic protein, from Mouse-ear cress, contains 453 amino acids, is membrane-bound, locates in Plastid.

Chaperone required for efficient photosystem II (PSII) assembly, Binds to psbA during de novo biogenesis of PSII


This is DNA gyrase subunit B, chloroplastic protein, from Mouse-ear cress, contains 730 amino acids, locates in Plastid.

A type II topoisomerase that negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner

Belongs to the type II topoisomerase GyrB family


This is Zinc finger protein AZF3 protein, from Mouse-ear cress, contains 193 amino acids, has 2 C2H2-type Zinc finger, locates in Nucleus.

Transcriptional repressor probably involved in abiotic stress responses, Binds DNA in a sequence-specific manner and can repress the transactivation activity of other transcription factors


This is Zinc finger protein AZF1 protein, from Mouse-ear cress, contains 245 amino acids, has 2 C2H2-type Zinc finger, locates in Nucleus.

Transcriptional repressor involved in the inhibition of plant growth under abiotic stress conditions, Can repress the expression of various genes, including osmotic stress and abscisic acid-repressive genes and auxin-inducible genes, by binding to their promoter regions in a DNA sequence-specific manner


This is Transcription initiation factor IIF subunit alpha protein, from Mouse-ear cress, contains 649 amino acids, locates in Nucleus.

TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB, It promotes transcription elongation (By similarity)

Belongs to the TFIIF alpha subunit family


This is Photosystem I reaction center subunit XI, chloroplastic protein, from Mouse-ear cress, contains 219 amino acids, is membrane-bound, locates in Plastid.


This is Probable cysteine protease RD19C protein, from Mouse-ear cress, contains 373 amino acids, locates in Lysosome/Vacuole.


This is Outer envelope membrane protein 7 protein, from Mouse-ear cress, contains 64 amino acids, is membrane-bound, locates in Plastid.


This is Protein ECERIFERUM 26 protein, from Mouse-ear cress, contains 428 amino acids, is soluble, locates in Cytoplasm.

Involved in biosynthesis of the epicuticular wax, Plays a role in very-long-chain fatty acid (VLCFA) biosynthesis and is required for C30 fatty acid elongation in leaf, Despite its classification as a BAHD acyltransferase based on sequence homology, CER26 does not seem to share the catalytic mechanism of the members of the BAHD family

Belongs to the plant acyltransferase family


This is Ammonium transporter 1 member 4 protein, from Mouse-ear cress, contains 504 amino acids, is membrane-bound, locates in Cell membrane.

High affinity ammonium transporter in the plasma membrane


This is Membrane-anchored ubiquitin-fold protein 3 protein, from Mouse-ear cress, contains 118 amino acids, is membrane-bound, locates in Cell membrane.

May serve as docking site to facilitate the association of other proteins to the plasma membrane


This is Pentatricopeptide repeat-containing protein At1g10270 protein, from Mouse-ear cress, contains 913 amino acids, locates in Nucleus.

May function as a transcriptional regulator essential for early embryogenesis


This is Protein FAR1-RELATED SEQUENCE 5 protein, from Mouse-ear cress, contains 788 amino acids, has 1 SWIM-type Zinc finger, locates in Nucleus.

SWIM-type

Putative transcription activator involved in regulating light control of development


This is Glucuronoxylan 4-O-methyltransferase 2 protein, from Mouse-ear cress, contains 290 amino acids, is membrane-bound, locates in Golgi apparatus.

Methyltransferase catalyzing 4-O-methylation of glucuronic acid side chains on xylan

Belongs to the methyltransferase superfamily


This is Leucine-rich repeat extensin-like protein 3 protein, from Mouse-ear cress, contains 760 amino acids, is soluble, locates in Extracellular.

Modulates cell morphogenesis by regulating cell wall formation and assembly, and/or growth polarization


This is Hairy/enhancer-of-split related with YRPW motif protein 1 protein, from Dog, contains 304 amino acids, locates in Nucleus.

Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3', Downstream effector of Notch signaling required for cardiovascular development, Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development, May be required in conjunction with HEY2 to specify arterial cell fate or identity, Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification, Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3


This is Platelet-activating factor receptor protein, from Bovine, contains 342 amino acids, is membrane-bound, locates in Cell membrane.

Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity, Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system, May be involved in the morphological and physical modifications of the oviduct and uterus during the estrus cycle and early pregnancy (By similarity)

Belongs to the G-protein coupled receptor 1 family


This is Peptidyl-prolyl cis-trans isomerase B protein, from Social amoeba, contains 197 amino acids, locates in Endoplasmic reticulum.

PPIases accelerate the folding of proteins, It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)

Belongs to the cyclophilin-type PPIase family


This is Histone H3.3 type 2 protein, from Caenorhabditis elegans, contains 136 amino acids, locates in Nucleus.

Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes, Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis, Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin, Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template, Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability, DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling


This is Peptidyl-prolyl cis-trans isomerase D, mitochondrial protein, from Social amoeba, contains 174 amino acids, locates in Mitochondrion.

Belongs to the cyclophilin-type PPIase family, PPIase D subfamily


This is mRNA turnover protein 4 homolog protein, from Human, contains 239 amino acids, locates in Cytoplasm.

Component of the ribosome assembly machinery, Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes

Belongs to the universal ribosomal protein uL10 family


This is Paladin protein, from Human, contains 856 amino acids, is soluble, locates in Cytoplasm.


This is TFIIA-alpha and beta-like factor protein, from Human, contains 478 amino acids, locates in Nucleus.

May function as a testis specific transcription factor, Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription


This is High temperature lethal protein 1 protein, from Baker's yeast, contains 78 amino acids, locates in Nucleus.

Required for cell cycle progression through G2/M transition at temperatures higher than 33 degrees Celsius, Component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning, RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA, The reaction requires ATP and involves an activated RSC-nucleosome intermediate, Remodeling reaction also involves DNA translocation, DNA twist and conformational change, As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton, When associated with the RSC complex, may act coordinately with PKC1 to regulate G2/M transition, Together with LDB7, NPL6, RSC3, RSC30 components, defines a fungal-specific module within the RSC complex that plays a role in many cellular functions including the maintenance of cell wall integrity


This is Protein arginine N-methyltransferase 1 protein, from Fission yeast, contains 340 amino acids, locates in Nucleus.

S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that catalyzes both the mono- and asymmetric (type I) dimethylation of the guanidino nitrogens of arginine residues in target proteins (By similarity), Asymmetrically dimethylates the polyadenylate-binding protein pab2, modulating pab2 oligomerization (PubMed:17213188)

Belongs to the class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family


This is Mitochondrial transcription factor 1 protein, from Fission yeast, contains 366 amino acids, locates in Mitochondrion.

Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase, Interacts with DNA in a non-specific manner

Belongs to the class I-like SAM-binding methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family


This is Nucleoporin nup61 protein, from Fission yeast, contains 549 amino acids, locates in Nucleus.

Functions as a component of the nuclear pore complex (NPC), NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors, Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope, May play a role in mitotic spindle formation and/or function


This is Chromosome transmission fidelity protein 18 protein, from Fission yeast, contains 960 amino acids, locates in Nucleus.

Essential for the fidelity of chromosome transmission, Required for the DNA replication block checkpoint, Replication factor C (RFC) complex has an essential but redundant activity in sister chromatid cohesion establishment, Acts as a PCNA loader, loading PCNA onto primed templates, An RFC-like complex (ctf18-RFC) is formed where ctf18 replaces rfc1 in the RFC complex along with the association of dcc1 and ctf8, This complex is required for efficient establishment of chromosome cohesion during S-phase

Belongs to the activator 1 small subunits family, CTF18 subfamily


This is DNA excision repair protein ckn1 protein, from Fission yeast, contains 404 amino acids, is soluble, locates in Cytoplasm.

Adapter protein for ddb1/cullin 4 ubiquitin ligases involved in transcription-coupled nucleotide excision repair


This is Serine/threonine-protein kinase ppk29 protein, from Fission yeast, contains 872 amino acids, is soluble, locates in Cytoplasm.

Belongs to the protein kinase superfamily, Ser/Thr protein kinase family


This is Ras guanine nucleotide exchange factor efc25 protein, from Fission yeast, contains 987 amino acids, is soluble, locates in Cytoplasm.

Has a role in chromosome segregation and cell morphology upstream of the ras1-scd1 pathway, Promotes the exchange of ras1-bound GDP by GTP leading to its activation


This is Copper transport protein ctr6 protein, from Fission yeast, contains 148 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Mobilizes stored copper from the vacuole to the cytoplasm under conditions of copper limitation

Belongs to the copper transporter (Ctr) (TC 1,A,56) family, SLC31A subfamily


This is Ataxin-2 homolog protein, from Fission yeast, contains 791 amino acids, is soluble, locates in Cytoplasm.

Involved in post-transcriptional regulation of gene expression, probably by association with mkt1


This is DNA repair protein rad60 protein, from Fission yeast, contains 406 amino acids, locates in Nucleus.

Required for repair of DNA double strand breaks which occur during replication, or induced by UV or gamma radiation, via recombination between sister chromatids, This has a subsequent role in the maintenance of chromosome structure, May work in conjunction with the Smc5-Smc6 complex


This is Serine/threonine-protein kinase ppk22 protein, from Fission yeast, contains 526 amino acids, is soluble, locates in Cytoplasm.

Belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family


This is U2 small nuclear ribonucleoprotein A' protein, from Fission yeast, contains 239 amino acids, locates in Nucleus.

Involved in pre-mRNA splicing, This protein is associated with sn-RNP U2, It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity)

Belongs to the U2 small nuclear ribonucleoprotein A family


This is Transcriptional regulatory protein moc3 protein, from Fission yeast, contains 508 amino acids, locates in Nucleus.

Induces sexual development and ascus formation, Also involved in calcium homeostasis


This is Ribonuclease MRP protein subunit rmp1 protein, from Fission yeast, contains 211 amino acids, is membrane-bound, locates in Nucleus.

Functions as part of ribonuclease MRP (RNase MRP), which is involved in rRNA processing in mitochondria


This is Ribonucleases P/MRP protein subunit pop1 protein, from Fission yeast, contains 698 amino acids, locates in Nucleus.

Required for processing of 5,8S rRNA (short form) at site A3 and for 5' and 3' processing of pre-tRNA


This is Iron sulfur cluster assembly protein 1, mitochondrial protein, from Fission yeast, contains 192 amino acids, is soluble, locates in Mitochondrion.

Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins, First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein isu1, In a second step, the cluster is released from isu1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins, Cluster assembly on isu1 depends on the function of the cysteine desulfurase complex nfs1-isd11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH


This is Protein sey1 protein, from Fission yeast, contains 762 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network, Has GTPase activity, which is required for its function in ER organization

Belongs to the TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3 GTPase family, RHD3 subfamily


This is Putative elongation of fatty acids protein 1 protein, from Fission yeast, contains 334 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

May be involved in the synthesis of very long chain fatty acids


This is Probable thymidylate synthase protein, from Fission yeast, contains 625 amino acids, is soluble, locates in Cytoplasm.

Required for both nuclear and mitochondrial DNA synthesis

In the C-terminal section; belongs to the thymidylate synthase family


This is Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase C144.17c protein, from Fission yeast, contains 449 amino acids, is soluble, locates in Cytoplasm.

Synthesis and degradation of fructose 2,6-bisphosphate

In the C-terminal section; belongs to the phosphoglycerate mutase family


This is Kinetochore protein mis13 protein, from Fission yeast, contains 329 amino acids, locates in Nucleus.

Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle, Required for correct segregation of chromosomes and for maintaining the inner centromere structure


This is Peptidyl-prolyl cis-trans isomerase cyp6 protein, from Fission yeast, contains 432 amino acids, locates in Nucleus.

PPIases accelerate the folding of proteins, It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)

Belongs to the cyclophilin-type PPIase family, PPIL4 subfamily


This is Ribosome production factor 2 homolog protein, from Fission yeast, contains 317 amino acids, locates in Nucleus.


This is Replication termination factor 1 protein, from Fission yeast, contains 466 amino acids, locates in Nucleus.

Mediates site-specific replication termination at the polar replication barrier RTS1, a barrier which ensures that replication of the mat1 locus in S,pombe occurs in the centromere-proximal direction


This is Beta-mannosidase A protein, from Aspergillus niger, contains 931 amino acids, is soluble, locates in Extracellular.

Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of beta-mannosidic oligosaccharides of various complexity and length, Involved in the degradation of polymeric mannan and galactomannan, Releases the terminal mannose residue from mannobiose and mannotriose, as well as from galactosyl-mannobiose (GM2), galactosyl-mannotriose (GM3) and di-galactosyl-mannopentaose (G2M5)

Belongs to the glycosyl hydrolase 2 family, Beta-mannosidase A subfamily


This is Trihydrophobin protein, from Ergot fungus, contains 394 amino acids, is soluble, locates in Extracellular.

Self-assembles at hydrophilic-hydrophobic interfaces on hyphal surface, Reduces water surface tension dramatically upon assembly at the water-air interface, Probable role in growth of aerial hyphae

Belongs to the cerato-ulmin hydrophobin family


This is Protein slowmo protein, from Fruit fly, contains 215 amino acids, locates in Mitochondrion.

Required to regulate peristaltic movement and also for germline proliferation in males and females


This is Protein preli-like protein, from Fruit fly, contains 236 amino acids, locates in Mitochondrion.

Involved in maintaining the structural and functional integrity of mitochondria (PubMed:19855018), Activity is required for maintaining the subcellular distribution, shape and activity of mitochondria in neurons and as a consequence has an important role in the development and maintenance of dendritic arbors (PubMed:19855018), Function may be particularly important in class IV dendritic arborization (da) neurons (PubMed:19855018)


This is Deoxyhypusine hydroxylase protein, from Fruit fly, contains 302 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor (By similarity), Essential for organismal viability and plays a role in a wide number of important processes such as cell growth and proliferation, and regulates induction of autophagy and protein synthesis, Has a role in eIF-5A-mediated translational control

Belongs to the deoxyhypusine hydroxylase family


This is Protein Diedel protein, from Fruit fly, contains 115 amino acids, is soluble, locates in Extracellular.

Cytokine which promotes survival following infection by Sindbis virus by suppressing the immune deficiency pathway (PubMed:26739560), Following infection by the enteropathogenic bacteria E,carotovora limits intestinal stem cells proliferation (PubMed:30036358), When secreted from muscle or adipose tissue, can attenuate age-related intestinal tissue degeneration by inhibiting apoptosis (PubMed:30036358)


This is Mitoferrin protein, from Fruit fly, contains 379 amino acids, is membrane-bound, locates in Mitochondrion.

Mitochondrial iron transporter that mediates iron uptake, Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly

Belongs to the mitochondrial carrier (TC 2,A,29) family


This is Probable ATP-dependent RNA helicase pitchoune protein, from Fruit fly, contains 680 amino acids, locates in Nucleus.

Probable RNA-dependent helicase, Functions in cell growth and proliferation, May have a role in ribosome biogenesis and, consequently, in protein biosynthesis

Belongs to the DEAD box helicase family, DDX18/HAS1 subfamily


This is Actin-related protein 5 protein, from Fruit fly, contains 648 amino acids, locates in Nucleus.

Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair

Belongs to the actin family, ARP5 subfamily


This is Dimethyladenosine transferase 2, mitochondrial protein, from Fruit fly, contains 452 amino acids, locates in Mitochondrion.

Probable S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop, Also required for basal transcription of mitochondrial DNA, Also regulates mitochondrial DNA copy number, Stimulates transcription independently of the methyltransferase activity

Belongs to the class I-like SAM-binding methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family, KsgA subfamily


This is Protein Turandot F protein, from Fruit fly, contains 125 amino acids, is soluble, locates in Extracellular.

A humoral factor that may play a role in stress tolerance


This is Vitelline membrane protein Vm32E protein, from Fruit fly, contains 116 amino acids, is soluble, locates in Extracellular.

Belongs to the vitelline membrane family


This is WD repeat-containing protein 82 protein, from Fruit fly, contains 317 amino acids, locates in Nucleus.

Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 (PubMed:21694722, PubMed:21875999), Together with su(sable), part of a transcription termination checkpoint that promotes transcription termination of aberrant RNAs and their subsequent degradation by the nuclear exosome (PubMed:26577379)


This is RNA polymerase II transcriptional coactivator protein, from Fruit fly, contains 110 amino acids, locates in Nucleus.

General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery, Binds single-stranded DNA (By similarity), Binds specifically to the NssBF element, a short nucleotide sequence of the 1731 retrotransposon, to repress promoter activity

Belongs to the transcriptional coactivator PC4 family


This is WW domain-containing oxidoreductase protein, from Fruit fly, contains 409 amino acids, is soluble, locates in Cytoplasm.

Putative oxidoreductase, May control genotoxic stress-induced cell death, May play a role in TGFB1 signaling and TGFB1-mediated cell death, May also play a role in tumor necrosis factor (TNF)-mediated cell death, May play a role in Wnt signaling (By similarity)

Belongs to the short-chain dehydrogenases/reductases (SDR) family


This is Elongation factor G, mitochondrial protein, from Fruit fly, contains 745 amino acids, locates in Mitochondrion.

Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation, During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively, Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity), Essential during development as it acts as a retrograde signal from mitochondria to the nucleus to slow down cell proliferation if mitochondrial energy output is low

Belongs to the TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, EF-G/EF-2 subfamily


This is 5'-3' exoribonuclease 2 homolog protein, from Fruit fly, contains 908 amino acids, has 1 CCHC-type Zinc finger, locates in Nucleus.

CCHC-type

Possesses 5'->3' exoribonuclease activity, May promote the termination of transcription by RNA polymerase II (By similarity)

Belongs to the 5'-3' exonuclease family, XRN2/RAT1 subfamily


This is Protein downstream neighbor of son homolog protein, from Fruit fly, contains 568 amino acids, locates in Nucleus.

Essential for DNA amplification in the ovary and required for cell proliferation during development


This is Cleavage and polyadenylation specificity factor subunit 4 protein, from Fruit fly, contains 296 amino acids, has 5 C3H1-type Zinc finger, has 2 CCHC-type Zinc finger, locates in Nucleus.

CCHC-type

CCHC-type

Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition, Has endonuclease activity, Binds RNA polymers with a preference for G- and/or C-rich clusters, Binds single-stranded DNA non-specifically


This is Vesicle transport protein USE1 protein, from Fruit fly, contains 250 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER (By similarity), Required for protein secretion


This is Protein tamozhennic protein, from Fruit fly, contains 797 amino acids, has 1 RanBP2-type Zinc finger, is soluble, locates in Cytoplasm.

Has an essential role during oogenesis and embryogenesis, perhaps in modulating the levels of nuclear import of additional proteins, Modulates the nuclear import of dorsal (dl), Dif and male specific lethal 1 (msl-1), Negatively regulates nuclear import of dl and controls the accumulation of dl in the nucleus after immune challenge


This is DNA ligase 1 protein, from Fruit fly, contains 747 amino acids, locates in Nucleus.

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair

Belongs to the ATP-dependent DNA ligase family


This is CXXC-type zinc finger protein 1 protein, from Fruit fly, contains 663 amino acids, has 1 PHD-type Zinc finger, has 1 CXXC-type Zinc finger, locates in Nucleus.

PHD-type

CXXC-type

Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3, Essential for Set1 association with chromatin and trimethylation of histone H3 at 'Lys-4' at transcription puffs, Additionally, is critical for general chromosomal association of Set1


This is Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase protein, from Fruit fly, contains 511 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation, Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity), Functions in developmental processes such as germband extension, the apical constriction of mesoderm precursor cells and ventral furrow formation in early embryogenesis prior to gastrulation (PubMed:24681004), Involved in the glycosylation and intracellular distribution of shg (E-cadherin) (PubMed:24681004), Function in cell intercalation in the lateral epidermis during germband extension may be due to its effect on shg (PubMed:24681004)

Belongs to the ALG6/ALG8 glucosyltransferase family


This is Four and a half LIM domains protein 5 protein, from Mouse, contains 284 amino acids, has 1 C4-type Zinc finger, locates in Nucleus.

May be involved in the regulation of spermatogenesis, Stimulates CREM transcriptional activity in a phosphorylation-independent manner (By similarity)


This is GTP-binding protein REM 2 protein, from Rat, contains 341 amino acids, is membrane-bound, locates in Cell membrane.

Binds GTP saturably and exhibits a low intrinsic rate of GTP hydrolysis

Belongs to the small GTPase superfamily, RGK family


This is Scarecrow-like protein 14 protein, from Mouse-ear cress, contains 769 amino acids, locates in Nucleus.

Probable transcription factor involved in plant development


This is DNA repair protein RAD51 homolog B protein, from Maize, contains 340 amino acids, locates in Nucleus.

Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity, Unwinds duplex DNA (By similarity), Component of the meiotic recombination pathway, Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis, Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination

Belongs to the RecA family, RAD51 subfamily


This is Aquaporin PIP2-5 protein, from Maize, contains 285 amino acids, is membrane-bound, locates in Cell membrane.

Water channel required to facilitate the transport of water across cell membrane, Its function is impaired by Hg(2+), May play a role in water uptake from the root surface, Active as homomers, Increased activity when heteromerization with PIP1-2

Belongs to the MIP/aquaporin (TC 1,A,8) family, PIP (TC 1,A,8,11) subfamily


This is Thioredoxin F2, chloroplastic protein, from Mouse-ear cress, contains 185 amino acids, is soluble, locates in Plastid.

Probable thiol-disulfide oxidoreductase involved in the redox regulation of enzymes of both reductive pentose phosphate pathway (Calvin-Benson cycle) and oxidative pentose phosphate pathway

Belongs to the thioredoxin family, Plant F-type subfamily


This is Potassium inward rectifier (Kir)-like channel 3 protein, from Mouse-ear cress, contains 260 amino acids, is membrane-bound, locates in Lysosome/Vacuole.

Probable calcium-activated potassium channel

Belongs to the two pore domain potassium channel (TC 1,A,1,7) family


This is Homeobox-leucine zipper protein HOX4 protein, from Rice, contains 277 amino acids, locates in Nucleus.

Probable transcription activator that binds to the DNA sequence 5'-CAAT[AT]ATTG-3', May be involved in the regulation of gibberellin signaling

Belongs to the HD-ZIP homeobox family, Class I subfamily


This is B3 domain-containing protein REM19 protein, from Mouse-ear cress, contains 226 amino acids, locates in Nucleus.

Involved in the regulation of vernalization (By similarity), Binds to DNA in vitro in a non-sequence-specific manner, XLG2 promotes the DNA binding activity of RTV1 specifically to promoter regions of FT and SOC1 in vivo and thus leads to the activation of floral integrator genes


This is Iron-sulfur assembly protein IscA, chloroplastic protein, from Mouse-ear cress, contains 180 amino acids, is soluble, locates in Plastid.

Involved in the assembly of chloroplastic iron-sulfur proteins, Is able to transfer iron-sulfur clusters to apo-ferredoxin

Belongs to the HesB/IscA family, Ycf83 subfamily


This is Peptidyl-prolyl cis-trans isomerase FKBP5 protein, from Bolivian squirrel monkey, contains 457 amino acids, is soluble, locates in Cytoplasm.

Immunophilin protein with PPIase and co-chaperone activities, Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) (PubMed:12538866), Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded (PubMed:11089542), Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1, Interacts with IKBKE and IKBKB which facilitates IKK complex assembly leading to increased IKBKE and IKBKB kinase activity, NF-kappaB activation, and IFN production (By similarity)


This is Myosin-2 essential light chain protein, from Caenorhabditis elegans, contains 142 amino acids, is soluble, locates in Cytoplasm.

Required for cytokinesis and embryo elongation, May regulate myosin II complex formation and/or the association of myosin with actin, May be involved in the organization of mlc-4 and nmy-2 into bundles


This is Negative elongation factor B protein, from Fruit fly, contains 594 amino acids, locates in Nucleus.

Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II


This is ER membrane protein complex subunit 9 protein, from Human, contains 208 amino acids, is soluble, locates in Cytoplasm.

Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:30415835, PubMed:29809151, PubMed:29242231, PubMed:32459176), Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:30415835, PubMed:29809151, PubMed:29242231), Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:30415835, PubMed:29809151), It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes (PubMed:29809151, PubMed:29242231), By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (PubMed:30415835), By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable)


This is Nucleolar protein 16 protein, from Human, contains 178 amino acids, locates in Nucleus.


This is Calcium-activated chloride channel regulator family member 3 protein, from Human, contains 262 amino acids, is soluble, locates in Extracellular.


This is Sporulation-specific protein 6 protein, from Fission yeast, contains 474 amino acids, has 1 DBF4-type Zinc finger, locates in Nucleus.

May act as a kinase regulator, Essential for progression of meiosis II and sporulation


This is SWR1 complex bromodomain subunit bdf1 protein, from Fission yeast, contains 578 amino acids, locates in Nucleus.

Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling


This is Monothiol glutaredoxin-3 protein, from Fission yeast, contains 166 amino acids, locates in Nucleus.

Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters (By similarity), Binds one iron-sulfur cluster per dimer, The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit (By similarity)

Belongs to the glutaredoxin family, Monothiol subfamily


This is ERO1-like protein 2 protein, from Fission yeast, contains 567 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds, Acts by oxidizing directly pdi1 isomerase through a direct disulfide exchange, Does not act as a direct oxidant of folding substrate, but relies on pdi1 to transfer oxidizing equivalent, Does not oxidize all pdi related proteins, suggesting that it can discriminate between pdi1 and related proteins, Its reoxidation probably involves electron transfer to molecular oxygen via FAD, Acts independently of glutathione, May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress


This is Actin-like protein arp5 protein, from Fission yeast, contains 721 amino acids, locates in Nucleus.

Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair


This is Histone acetyltransferase rtt109 protein, from Fission yeast, contains 369 amino acids, locates in Nucleus.

Histone chaperone-dependent acetylase that modifies 'Lys-56' of histone H3 (H3K56ac), which occurs predominantly in newly synthesized H3 molecule during G1, S-phase and G2/M of cell cycle (PubMed:17369611, PubMed:17690098, PubMed:20656950), Histone H3 'Lys-56' acetylation is required for S-phase-linked DNA damage tolerance and proper silencing in pericentromeric heterochromatin (PubMed:17369611)


This is Gamma-bungarotoxin protein, from Many-banded krait, contains 89 amino acids, is soluble, locates in Extracellular.

Exhibits M2 muscarinic acetylcholine receptor (CHRM2)-blocking activity, but has a weak binding activity toward nicotinic AChR, Moreover, it inhibits collagen-induced platelet aggregation

Belongs to the snake three-finger toxin family, Ancestral subfamily, Orphan group V sub-subfamily


This is Protein LSM14 homolog protein, from Iberian ribbed newt, contains 467 amino acids, is soluble, locates in Cytoplasm.


This is Cell division control protein 45 homolog protein, from African clawed frog, contains 567 amino acids, locates in Nucleus.

Required for initiation of chromosomal DNA replication, Binds to chromatin in a mutually dependent manner with the GINS DNA replication complex


This is Target of rapamycin complex subunit LST8 protein, from Rat, contains 326 amino acids, is soluble, locates in Cytoplasm.

Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals, mTORC1 is activated in response to growth factors or amino acids, Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1, Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases, Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis, mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E), mTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation, Within mTORC1, LST8 interacts directly with MTOR and enhances its kinase activity, In nutrient-poor conditions, stabilizes the MTOR-RPTOR interaction and favors RPTOR-mediated inhibition of MTOR activity, mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive, mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors, mTORC2 promotes the serum-induced formation of stress-fibers or F-actin, mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation, mTORC2 regulates the phosphorylation of SGK1 at 'Ser-421', mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657' (By similarity)


This is Lysine-rich nucleolar protein 1 protein, from Mouse, contains 478 amino acids, locates in Nucleus.


This is Glycine N-acyltransferase-like protein Keg1 protein, from Rat, contains 295 amino acids, is soluble, locates in Cytoplasm.

Acyltransferase which transfers the acyl group to the N-terminus of glycine, Can conjugate a multitude of substrates to form a variety of N-acylglycines (By similarity)

Belongs to the glycine N-acyltransferase family


This is Keratin, type I cytoskeletal 27 protein, from Mouse, contains 448 amino acids, is soluble, locates in Cytoplasm.

Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs)

Belongs to the intermediate filament family


This is Pyridoxal 5'-phosphate synthase-like subunit PDX1.2 protein, from Mouse-ear cress, contains 314 amino acids, is soluble, locates in Cytoplasm.

The protein has no function in the formation of pyridoxal 5'-phosphate


This is Prohibitin-2, mitochondrial protein, from Mouse-ear cress, contains 286 amino acids, is membrane-bound, locates in Mitochondrion.

Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins


This is Avenacosidase 2 protein, from Oat, contains 578 amino acids, is soluble, locates in Plastid.

Beta-glucosidase acting as a preformed defense system, Hydrolyzes the bisdesmosides avenacosides A and B to 26-desgluco-avenacosides exhibiting fungicidal activity, Can use beta-fucoside > beta-glucoside > beta-galactoside > beta-xyloside as substrates, but not alpha-glycosides, beta-thioglucosides and disaccharides (By similarity)

Belongs to the glycosyl hydrolase 1 family


This is Protein EXORDIUM protein, from Mouse-ear cress, contains 314 amino acids, is soluble, locates in Extracellular.

Required for cell expansion in leaves, May mediate brassinosteroid (BR)-induced leaf growth, May play a role in the control of BR responses in roots, May be involved in signaling processes that coordinate BR responses with environmental or developmental signals


This is Glutathione S-transferase T1 protein, from Mouse-ear cress, contains 245 amino acids, locates in Nucleus.

In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrobenzyl chloride (pNBC), and glutathione peroxidase activity toward cumene hydroperoxide and linoleic acid-13-hydroperoxide, May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides

Belongs to the GST superfamily, Theta family


This is Elongation factor Tu, mitochondrial protein, from Mouse-ear cress, contains 454 amino acids, locates in Mitochondrion.

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis

Belongs to the TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, EF-Tu/EF-1A subfamily


This is Nicotinate-nucleotide pyrophosphorylase [carboxylating], chloroplastic protein, from Mouse-ear cress, contains 348 amino acids, locates in Plastid.

Involved in the biosynthesis of NAD(+) (PubMed:16698895), Catalyzes the conversion of quinolate to nicotinate to nicotinate beta-D-ribonucleotide (PubMed:16698895)


This is Probable ribose-5-phosphate isomerase 2 protein, from Mouse-ear cress, contains 265 amino acids, is soluble, locates in Cytoplasm.

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate

Belongs to the ribose 5-phosphate isomerase family


This is Arginine biosynthesis bifunctional protein ArgJ, chloroplastic protein, from Mouse-ear cress, contains 468 amino acids, locates in Plastid.

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate


This is Protein ALUMINUM SENSITIVE 3 protein, from Mouse-ear cress, contains 273 amino acids, is membrane-bound, locates in Cell membrane.

Required for aluminum (Al) resistance/tolerance, probably by translocating Al from sensitive tissues such as growing roots to tissues less sensisitive to the toxic effects of Al


This is N-acylphosphatidylethanolamine synthase protein, from Mouse-ear cress, contains 284 amino acids, is membrane-bound, locates in Cell membrane.

Acyltransferase that catalyzes the N-acylation of phosphatidylethanolamine to form N-acylphosphatidylethanolamine (N-acyl-PE) (e,g, NAPEs containing C16:0, C16:1, C18:0, and C18:1), Mediates also the formation of acylphosphatidylglycerol (acyl-PG) from lysoglycerophospholipid by O-acylation, Uses acyl-CoA as acyl donors, Acylates 1-acyllysophosphatidylethanolamine (1-acyllyso-PE) and 1-acyllysophosphatidylglycerol (1-acyllyso-PG) at the sn-2-position


This is Probable NAD(P)H dehydrogenase subunit CRR3, chloroplastic protein, from Mouse-ear cress, contains 174 amino acids, is membrane-bound, locates in Plastid.

Probable subunit of the chloroplast NAD(P)H dehydrogenase (NDH) complex of the photosynthetic electron transport chain, Required for both formation and activity of NDH, May function in assembly or stabilization of the NDH complex


This is Protein FEZ protein, from Mouse-ear cress, contains 418 amino acids, locates in Nucleus.

Promotes periclinal root capforming cell divisions, Activates expression of its negative regulator SMB in a feedback loop for controlled switches in cell division plane


This is Photosystem II D1 precursor processing protein PSB27-H2, chloroplastic protein, from Mouse-ear cress, contains 199 amino acids, locates in Plastid.

Required, but not essential, for D1 (psbA) precursor processing and thus correct photosystem II assembly (PSII)


This is Zinc finger CCCH domain-containing protein 2 protein, from Mouse-ear cress, contains 393 amino acids, has 2 C3H1-type Zinc finger, locates in Nucleus.

Probable transcription repressor that functions as negative regulator of phytochrome-mediated promotion of seed germination, Inhibits seed germination by regulating the expression of gibberellic acid (GA) and abscisic acid (ABA) metabolic genes, Does not regulate the expression of the DELLA genes RGA and RGA1, Activated by PIL5, a phytochrome-interacting basic helix-loop-helix transcription factor (PubMed:18487351), Represses directly JMJ20 and JMJ22 expression in the absence of red light (R) and in far-red (FR) conditions (PubMed:22483719)


This is Chlorophyllide a oxygenase, chloroplastic protein, from Chlamydomonas smithii, contains 645 amino acids, is membrane-bound, locates in Plastid.

Catalyzes a two-step oxygenase reaction involved in the synthesis of chlorophyll b, Acts specifically on the non-esterified chlorophyllide a and not on chlorophyll a


This is Anthocyanin 5-aromatic acyltransferase protein, from Clustered gentian, contains 469 amino acids, is soluble, locates in Cytoplasm.

Transfers hydroxycinnamic moieties to the glucosyl groups of anthocyanin

Belongs to the plant acyltransferase family


This is Two-component response regulator ARR6 protein, from Mouse-ear cress, contains 186 amino acids, locates in Nucleus.

Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system, Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes, Type-A response regulators seem to act as negative regulators of the cytokinin signaling

Belongs to the ARR family, Type-A subfamily


This is Hyaluronidase protein, from Brown spider, contains 400 amino acids, is soluble, locates in Extracellular.

Spider venom endo-hyaluronidase that is able to degrade purified hyaluronic acid (HA) and chondroitin sulfate (CS), Has no activity on dermatan sulfate (DS) and heparan sulfate (HS), Also increases the dermonecrotic effect of the dermonecrotic toxin (AC P0CE80), when injected in rabbit skin, supporting the hypothesis that venom hyaluronidases are spreading factors

Belongs to the glycosyl hydrolase 56 family


This is Tuliposide A-converting enzyme b1, amyloplastic protein, from Garden tulip, contains 374 amino acids, locates in Plastid.

Lactone-forming carboxylesterases, specifically catalyzing intramolecular transesterification, but not hydrolysis, Involved in the biosynthesis of tulipalins, defensive chemicals that show antimicrobial activities against a broad range of strains of bacteria and fungi, Substrates are 6-tuliposide A > 6-tuliposide B


This is Secondary metabolism regulator LAE1 protein, from Bakanae and foot rot disease fungus, contains 316 amino acids, locates in Nucleus.

Methyltransferase that performs automethylation (By similarity), No other methyl-accepting substrate has been identified yet (By similarity), Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (PubMed:20572938), Controls the expression of the gibberellins gene clusters, but does not affect bikaverin production (PubMed:20572938), Controls the expression of the fusaric acid gene cluster (PubMed:24389666), Acts as a virulence factors during infection, most likely through activation of gibberellins biosynthesis (PubMed:20572938)

Belongs to the methyltransferase superfamily, LaeA methyltransferase family


This is Kinetochore protein Sos7 protein, from Fission yeast, contains 264 amino acids, locates in Nucleus.

Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle, Essential for chromosome segregation and bipolar sister chromatid association, Required for kinetochore targeting of MIND, but not Ndc80 complex components


This is Alpha-L-arabinofuranosidase A protein, from Penicillium canescens, contains 631 amino acids, is soluble, locates in Extracellular.

Secreted alpha-L-arabinofuranosidase that actively hydrolyzes p-NP-alpha-L-arabinofuranoside, Exhibits significant activity against polymeric arabinose-containing substrates such as arabinan and arabinoxylan, Hydrolyzes also low-molecular-weight and polymeric galactoside-containing substrates such as galactan, xyloglycan, and p-NP-beta-D-galactopyranoside

Belongs to the glycosyl hydrolase 51 family


This is Endo-1,4-beta-xylanase 2 protein, from Mucormycosis agent, contains 216 amino acids, is soluble, locates in Extracellular.

Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose

Belongs to the glycosyl hydrolase 11 (cellulase G) family


This is Cell pattern formation-associated protein stuA protein, from Acremonium chrysogenum (strain ATCC 11550 / CBS 779.69 / DSM 880 / IAM 14645 / JCM 23072 / IMI 49137), contains 623 amino acids, locates in Nucleus.

Transcription factor that regulates asexual reproduction (PubMed:26283234), Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity), Controls conidiation by positively regulating the expression of brlA and abaA (PubMed:26283234), Positively regulates the cephalosporin biosynthesis gene cluster (PubMed:26283234), Also involved hyphal fragmentation and cell wall integrity (PubMed:26283234)


This is Nuclear speckle RNA-binding protein A protein, from Mouse-ear cress, contains 233 amino acids, locates in Nucleus.

Alternative splicing (AS) regulator that binds to specific mRNAs and modulates auxin effects on the transcriptome, Displaced from its targets upon binding to AS competitor long non-coding RNA (ASCO-RNA)


This is Subtilisin-like protease 6 protein, from Horse ringworm fungus, contains 412 amino acids, is soluble, locates in Extracellular.

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity


This is Subtilisin-like protease 6 protein, from Trichophyton soudanense, contains 412 amino acids, is soluble, locates in Extracellular.


This is Subtilisin-like protease 7 protein, from Horse ringworm fungus, contains 401 amino acids, is soluble, locates in Extracellular.


This is Subtilisin-like protease 7 protein, from Scalp ringworm fungus, contains 401 amino acids, is soluble, locates in Extracellular.


This is Subtilisin-like protease 7 protein, from Trichophyton soudanense, contains 400 amino acids, is soluble, locates in Extracellular.


This is Subtilisin-like protease 7 protein, from Trichophyton violaceum, contains 400 amino acids, is soluble, locates in Extracellular.


This is Antimicrobial protein 1 protein, from Mud crab, contains 126 amino acids, is soluble, locates in Extracellular.

Has antibacterial activity against the Gram-positive bacteria E,coli (MIC<50 ug/ml) and P,aeruginosa (MIC<25 ug/ml), and the Gram-negative bacteria S,aureus (MIC<100 ug/ml) and S,pyogenes (MIC<50 ug/ml)


This is Mitochondrial import receptor subunit TOM40 homolog 2 protein, from Fruit fly, contains 340 amino acids, is membrane-bound, locates in Mitochondrion.

Channel-forming protein essential for import of protein precursors into mitochondria


This is Putative PIP5K1A and PSMD4-like protein protein, from Human, contains 862 amino acids, is soluble, locates in Cytoplasm.

Has negligible PIP5 kinase activity, Binds to ubiquitinated proteins


This is Dystrotelin protein, from Mouse, contains 653 amino acids, has 1 ZZ-type Zinc finger, is membrane-bound, locates in Cell membrane.

ZZ-type


This is Neurotoxin 3FTx-8a protein, from Banded krait, contains 86 amino acids, is soluble, locates in Extracellular.

Binds with low affinity to muscular (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and very low affinity to neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR)

Belongs to the snake three-finger toxin family, Ancestral subfamily, Orphan group II sub-subfamily


This is Neurotoxin 3FTx-LT protein, from Banded krait, contains 86 amino acids, is soluble, locates in Extracellular.


This is Beta-glucuronidase protein, from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513), contains 541 amino acids, is soluble, locates in Extracellular.

Beta-glucuronidase that hydrolyzes beta-glucuronosyl and 4-O-methyl-beta-glucuronosyl residues of arabinogalactan-protein, Hydrolyzed heparan sulfate only very weakly, Has no activity on xylan from birchwood, Able to catalyze the transglycosylation of glucuronic acid (GlcA) residues from p-nitrophenyl-beta-glucuronic acid (PNP beta-GlcA) to various monosaccharide acceptors such as glucose, galactose and xylose

Belongs to the glycosyl hydrolase 79 family


This is Protein EFFECTOR OF TRANSCRIPTION protein, from Rape, contains 440 amino acids, locates in Nucleus.

Transcription regulator that negatively modulates gibberellin-mediated developmental processes, May act as transcriptional repressor of giberellin controlled genes, Binds DNA without sequence preference


This is Pentatricopeptide repeat-containing protein 1, mitochondrial protein, from Rat, contains 686 amino acids, is soluble, locates in Mitochondrion.

Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria-encoded proteins and COX activity, Affects also the 3'-processing of mitochondrial tRNAs


This is Auxin-responsive protein IAA13 protein, from Rice, contains 236 amino acids, locates in Nucleus.

Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations


This is Metallothionein-like protein 2C protein, from Rice, contains 84 amino acids, is soluble, locates in Cytoplasm.

Metallothioneins have a high content of cysteine residues that bind various heavy metals (Probable), Acts as reactive oxygen species (ROS) scavenger in the cytosol, Possesses superoxide anion and hydroxyl radical scavenging activities in vitro (PubMed:15220467), Plays a role during root development, lateral root initiation and seed embryo germination, possibly by regulating levels of cytokinin (PubMed:18258694)

Belongs to the metallothionein superfamily, Type 15 family


This is Large ribosomal subunit protein mL37 protein, from Bovine, contains 423 amino acids, locates in Mitochondrion.

Belongs to the mitochondrion-specific ribosomal protein mL37 family


This is Riparin-1.4 protein, from Streambank froglet, contains 55 amino acids, is soluble, locates in Extracellular.


This is Riparin-1.5 acid protein, from Streambank froglet, contains 55 amino acids, is soluble, locates in Extracellular.


This is Carboxypeptidase 2 protein, from Athlete's foot fungus, contains 538 amino acids, is soluble, locates in Extracellular.

Extracellular metalloprotease that contributes to pathogenicity


This is Protein STAY-GREEN, chloroplastic protein, from Garden pea, contains 261 amino acids, locates in Plastid.

Probably involved in the disassembling mechanism of the intact light-harvesting complex of photosystem II (LHCII) in the thylakoid membranes, Required for the chlorophyll breakdown pathway, Acts independent and upstream of pheophorbide a oxygenase (PAO)


This is Esculentin-2PLa protein, from Pickerel frog, contains 78 amino acids, is soluble, locates in Extracellular.

Antimicrobial activity against the Gram-negative bacterium E,coli, the Gram-positive bacterium S,aureus and the yeast C,albicans

Belongs to the frog skin active peptide (FSAP) family, Esculentin subfamily


This is Ranatuerin-2PLa protein, from Pickerel frog, contains 71 amino acids, is soluble, locates in Extracellular.

May have antimicrobial activity against the Gram-negative bacterium E,coli

Belongs to the frog skin active peptide (FSAP) family, Ranatuerin subfamily


This is Sideroflexin-4 protein, from Zebrafish, contains 316 amino acids, is membrane-bound, locates in Mitochondrion.

Mitochondrial amino-acid transporter (By similarity), Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity)


This is Cilia- and flagella-associated protein 221 homolog protein, from Chlamydomonas smithii, contains 645 amino acids, is soluble, locates in Cytoplasm.


This is Tektin protein, from Chlamydomonas smithii, contains 482 amino acids, is soluble, locates in Cytoplasm.

Structural component of ciliary and flagellar microtubules, Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in flagella and cilia, Forms filamentous polymers in the walls of ciliary and flagellar microtubules


This is Protein LURE 1.5 protein, from Mouse-ear cress, contains 90 amino acids, is soluble, locates in Extracellular.

Inactive pollen tube attractants guiding pollen tubes to the ovular micropyle


This is Haditoxin protein, from King cobra, contains 86 amino acids, is soluble, locates in Extracellular.

Antagonist of muscle (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and neuronal (alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2, alpha-4-beta-2/CHRNA4-CHRNB2) nicotinic acetylcholine receptors (nAChR) (PubMed:20071329), The highest affinity is for human alpha-7/CHRNA7 nAChRs (IC(50)=180 nM), compared to human alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE nAChR (IC(50)= 550 nM), alpha-3-beta-2/CHRNA3-CHRNB2 nAChR (IC(50)=500 nM), and alpha-4-beta-2/CHRNA4-CHRNB2 nAChR (IC(50)=2,6 uM)

Belongs to the snake three-finger toxin family, Short-chain subfamily, Orphan group VIII (haditoxin) sub-subfamily


This is Large ribosomal subunit protein bL34m protein, from Bovine, contains 96 amino acids, locates in Mitochondrion.

Belongs to the bacterial ribosomal protein bL34 family


This is Extracellular exo-inulinase inuE protein, from Yeast, contains 514 amino acids, is soluble, locates in Extracellular.

Exo-inulinase involved in utilization of the plant storage polymer inulin, consisting of fructooligosaccharides with a degree of polymerization (DP) value from 2 to 60, Splits off terminal fructose units successively from the non-reducing end of the inulin molecule

Belongs to the glycosyl hydrolase 32 family


This is Facilitated trehalose transporter Tret1 protein, from Common honeybee, contains 502 amino acids, is membrane-bound, locates in Cell membrane.

Moderate-capacity facilitative transporter for trehalose, Does not transport maltose, sucrose or lactose, Mediates the bidirectional transfer of trehalose, Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph

Belongs to the major facilitator superfamily, Sugar transporter (TC 2,A,1,1) family, Trehalose transporter subfamily


This is Facilitated trehalose transporter Tret1 protein, from Silk moth, contains 505 amino acids, is membrane-bound, locates in Cell membrane.

High-capacity facilitative transporter for trehalose, Does not transport maltose, sucrose or lactose, Mediates the bidirectional transfer of trehalose, Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph


This is Golgin candidate 2 protein, from Mouse-ear cress, contains 668 amino acids, is membrane-bound, locates in Golgi apparatus.

Golgi matrix protein playing a role in tethering of vesicles to Golgi membranes and in maintaining the overall structure of the Golgi apparatus


This is Protein LLP protein, from Kuroda's sea hare, contains 120 amino acids, locates in Nucleus.

Acts as a transcriptional activator of C/EBP, Required for long-term synaptic facilitation at the sensory motor synapse, May function in noxious stimulus-facilitated memory formation

Belongs to the learning-associated protein family


This is Probable dipeptidyl peptidase 4 protein, from Neosartorya fumigata, contains 765 amino acids, is soluble, locates in Extracellular.

Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline, Contributes to pathogenicity


This is C2H2 finger domain transcription factor mtfA protein, from Neosartorya fumigata, contains 336 amino acids, has 2 C2H2-type Zinc finger, locates in Nucleus.

Transcription factor that controls morphogenesis and virulence, Acts as a positive regulator of gliotixin and protease production


This is Iron sulfur cluster assembly protein 1 protein, from Microsporidian parasite, contains 138 amino acids, is soluble, locates in Cytoplasm.

Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitosomes, which is required for maturation of both [2Fe-2S] and [4Fe-4S] proteins (PubMed:18311129), First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein ISU1, In a second step, the cluster is released from ISU1, transferred to a glutaredoxin, followed by the formation of [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins, Cluster assembly on ISU1 depends on the function of the cysteine desulfurase complex NFS1-ISD11, which serves as the sulfur donor for cluster synthesis, the iron-binding protein frataxin as the putative iron donor, and the electron transfer chain comprised of ferredoxin reductase and ferredoxin, which receive their electrons from NADH (By similarity)


This is Alpha-elapitoxin-Al2b protein, from Pygmy copperhead, contains 96 amino acids, is soluble, locates in Extracellular.

Potent long-chain postsynaptic neurotoxin, Pseudo-irreversibly inhibits the nicotinic acetylcholine receptor through competitive antagonism

Belongs to the snake three-finger toxin family, Long-chain subfamily, Type II alpha-neurotoxin sub-subfamily


This is Killin protein, from Human, contains 178 amino acids, locates in Nucleus.

DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis, Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis, Has affinity to both double- and single-stranded DNA


This is F-actin-capping protein subunit alpha-1 protein, from Rat, contains 286 amino acids, is soluble, locates in Cytoplasm.

F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends, Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments, May play a role in the formation of epithelial cell junctions (By similarity), Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure, The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity)

Belongs to the F-actin-capping protein alpha subunit family


This is Complex I assembly factor TMEM126B, mitochondrial protein, from Rat, contains 229 amino acids, is membrane-bound, locates in Mitochondrion.

As part of the MCIA complex, involved in the assembly of the mitochondrial complex I (PubMed:22982022), Participates in constructing the membrane arm of complex I (By similarity)


This is Putative carbonic anhydrase 1 protein, from Giant owl limpet, contains 395 amino acids, is soluble, locates in Extracellular.

Belongs to the alpha-carbonic anhydrase family


This is Putative peptidyl-prolyl cis-trans isomerase protein, from Giant owl limpet, contains 206 amino acids, is soluble, locates in Extracellular.

PPIases accelerate the folding of proteins, It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)

Belongs to the cyclophilin-type PPIase family


This is Three-finger hemachatoxin protein, from Rinkhals, contains 61 amino acids, is soluble, locates in Extracellular.

This protein lyses red blood cells and has cardiotoxic and hypotensive activities

Belongs to the snake three-finger toxin family, Short-chain subfamily, Type IB cytotoxin sub-subfamily


This is Toxin CSTX-10 protein, from American wandering spider, contains 116 amino acids, is soluble, locates in Extracellular.

Spider venom toxin that shows calcium channel blocking activity and exhibits cytolytic activity by affecting the outer leaflet curvature and/or pore formation across the membrane, It blocks L-type calcium channels (Cav1/CACNA1) in mammalian neurons at nanomolar concentrations, Furthermore, it produces a slow voltage-independent block of mid/low and high voltage-activated calcium channels in cockroach neurons, Potassium ions, histamine, M-ctenitoxin-Cs1a (AC P83619), CSTX-9 (AC P58604), and CSTX-13 (AC P83919) synergistically increase the insecticidal activity of this toxin, In vivo, it causes paralysis in blow flies and provokes death in drosophila

Belongs to the neurotoxin 19 (CSTX) family


This is Toxin CSTX-11 protein, from American wandering spider, contains 69 amino acids, is soluble, locates in Extracellular.


This is Conopeptide Y-Pl1 protein, from Planorbis cone, contains 69 amino acids, is soluble, locates in Extracellular.

Tyrosine-rich conopeptide that targets several channels/receptors that are expressed in Xenopus oocytes, These targets are the voltage-gated potassium channels Kv1,6/KCNA6 (IC(50) is 170 nM) and Kv1,2/KCNA2 (IC(50) is 2,0 uM), Nav1,2/SCN2A (30% of inhibition), and N-methyl-D-aspartate (NMDA) receptor (GRIN1/GRIN2A/GRIN3B and GRIN1/GRIN2B/GRIN3B) (15% of inhibition), In vivo, causes the marine worm N,virens to move very slowly in contrast to control worms, and causes seizures (at 5 nmol) and death (20 nmol) to mice when intracranially injected

Belongs to the conotoxin M superfamily, Conopeptide Y family


This is Conotoxin ca17a protein, from Characteristic cone, contains 74 amino acids, is soluble, locates in Extracellular.


This is Endo-1,4-beta-xylanase 2 protein, from Hypocrea lixii, contains 221 amino acids, is soluble, locates in Extracellular.

Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose

Belongs to the glycosyl hydrolase 11 (cellulase G) family


This is L-amino-acid oxidase protein, from Ocellated saw-scaled viper, contains 504 amino acids, is soluble, locates in Extracellular.

Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme, Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis of vascular endothelial cells or tumor cell lines, antibacterial and antiparasitic activities, as well as regulation of platelet aggregation, Its effect on platelets is controversial, since it either induces aggregation or inhibits agonist-induced aggregation, These different effects are probably due to different experimental conditions

Belongs to the flavin monoamine oxidase family, FIG1 subfamily


This is Cell pattern formation-associated protein stuA protein, from Penicillium chrysogenum, contains 818 amino acids, locates in Nucleus.

Transcription factor that regulates asexual reproduction (PubMed:21148688), Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity), Controls the expression of the penicillin gene cluster (PubMed:21148688)


This is Importin subunit alpha protein, from Penicillium chrysogenum, contains 552 amino acids, locates in Nucleus.

Import of proteins with classical NLS composed of one or two clusters of basic residues is initiated by binding to the importin alpha/beta heterodimer, where importin alpha acts as an adapter subunit to bridge NLS cargos to importin beta, which transports the whole complex through the nuclear envelope (By similarity), Involved in the nuclear accumulation of the light-dependent developmental regulator velA (PubMed:20543063)


This is Spore development regulator vosA protein, from Penicillium chrysogenum, contains 390 amino acids, locates in Nucleus.

Component of the velB-VosA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (PubMed:23264641), The complex binds DNA through the DNA-binding domain of vosA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity)

Belongs to the velvet family, VosA subfamily


This is Sexual development regulator velC protein, from Penicillium chrysogenum, contains 268 amino acids, locates in Nucleus.

Velvet-domain-containing protein that acts as a positive regulator of sexual development (By similarity)

Belongs to the velvet family, VelC subfamily


This is Riboflavin biosynthesis protein PYRD, chloroplastic protein, from Maize, contains 392 amino acids, locates in Plastid.

Monofunctional pyrimidine deaminase involved in the riboflavin biosynthesis pathway, Has also a reductase domain that lacks catalytically essential substrate-binding residues (By similarity)


This is Extracellular metalloproteinase 4 protein, from Scalp ringworm fungus, contains 643 amino acids, is soluble, locates in Extracellular.

Secreted metalloproteinase probably acting as a virulence factor


This is Extracellular metalloproteinase 3 protein, from Scalp ringworm fungus, contains 633 amino acids, is soluble, locates in Extracellular.


This is Auxin-responsive protein SAUR36 protein, from Rice, contains 171 amino acids, is soluble, locates in Cytoplasm.

Involved in the negative regulation of organ growth, May act as a negative regulator of auxin synthesis and transport


This is Glutaredoxin-1 protein, from Arbuscular mycorrhizal fungus, contains 101 amino acids, is soluble, locates in Cytoplasm.

Multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity, The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase, In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase, May play a role in protection against oxidative stress caused by superoxide in vivo by regulating the redox state of the protein sulfhydryl groups


This is (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic protein, from Wild tomato, contains 303 amino acids, locates in Plastid.

Specifically forms (2Z,6Z)-farnesyl diphosphate (Z,Z-FPP) from dimethylallyl diphosphate (DMAPP) and isopentenyl diphosphate (IPP), Also able to use nerylpyrophosphate (NPP) as substrate, Involved in the biosynthesis of several sesquiterpenes


This is Extracellular metalloproteinase 3 protein, from Horse ringworm fungus, contains 633 amino acids, is soluble, locates in Extracellular.


This is Serine protease inhibitor Cvsi-2 protein, from Eastern oyster, contains 85 amino acids, is soluble, locates in Extracellular.

Slow-binding inhibitor of serine proteases, The inhibitor rapidly binds to the protease forming a weak enzyme-inhibitor complex, and this is followed by a slow isomerization forming a tight-binding enzyme-inhibitor complex, Active against subtilisin A with a dissociation constant of 0,18 nM, Active against perkinsin, Not active against thermolysin, papain or pepsin


This is Probable methyltransferase PMT2 protein, from Mouse-ear cress, contains 616 amino acids, is membrane-bound, locates in Golgi apparatus.

Belongs to the methyltransferase superfamily


This is Signal peptide peptidase 2 protein, from Rice, contains 343 amino acids, is membrane-bound, locates in Endoplasmic reticulum.

Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane, Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm