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In the 14th century, diplomatic contact continued between the Franks and the Mongols, until the Ilkhanate dissolved in the 1330s, and the ravages of the Black Death in Europe caused contact with the East to be severed. A few marital alliances between Christian rulers and the Mongols of the Golden Horde continued, such as when the Byzantine emperor Andronicus II gave daughters in marriage to Toqto'a (d. 1312) and later to his successor Uzbek (1312–1341).After Abu Sa'id, relations between Christian princes and the Ilkhanate became very sparse. Abu Sa'id died in 1335 with neither heir nor successor, and the Ilkhanate lost its status after his death, becoming a plethora of little kingdoms run by Mongols, Turks, and Persians.In 1336, an embassy to the French Pope Benedict XII in Avignon was sent by Toghun Temür, the last Yuan emperor in Dadu. The embassy was led by two Genoese travelers in the service of the Mongol emperor, who carried letters representing that the Mongols had been eight years (since Archbishop John of Montecorvino's death) without a spiritual guide, and earnestly desired one. Pope Benedict appointed four ecclesiastics as his legates to the khan's court. In 1338, a total of 50 ecclesiastics were sent by the pope to Peking, among them John of Marignolli, who returned to Avignon in 1353 with a letter from the Yuan emperor to Pope Innocent VI. But soon, the Han Chinese rose up and drove the Mongols out of China, establishing the Ming Dynasty in 1368. By 1369, all foreign influences, from Mongols to Christians, Manichaeans, and Buddhists, were expelled by the Ming Dynasty.
In the early 15th century, Timur (Tamerlane) resumed relations with Europe, attempting to form an alliance against the Egyptian Mamluks and the Ottoman Empire, and engaged in communications with Charles VI of France and Henry III of Castile, but died in 1405.

Toghun Temür