Here's a question: John tried his best to care for Kate, but Kate kept throwing herself into danger.  He couldn't stand her what for her own safety?

Here are possible answers to this question:
- unfeeling
- disregard
- indifferent
- neglect
- apathetic

I believe the correct choice is "disregard", here's why:


disregard | definition of disregard by merriam-webster