Here's a question and a few possible answers: 

Q: John tried his best to care for Kate, but Kate kept throwing herself into danger.  He couldn't stand her what for her own safety?
Possible A: unfeeling, disregard, indifferent, neglect, apathetic

Why is "disregard" an answer aligned with human common sense? 


disregard | definition of disregard by merriam-webster