Question: When james was climbing he experiences a couple of symptoms.  The most painful and long lasting was on his hands.   What  might have happened to him?

Choices: 
- calluses
- loss of oxygen
- vertigo
- ascending
- blisters

The rationale to choose "blisters" as the answer is that: 

he experiences a couple of symptoms. the most painful and long lasting was on his hands blisters.