Answer the following question given this paragraph: 

A mixture is a combination of two or more substances in any proportion. This is different from a compound, which consists of substances in fixed proportions. The substances in a mixture also do not combine chemically to form a new substance, as they do in a compound. Instead, they just intermingle and keep their original properties. The lemonade pictured above is a mixture because it doesn’t have fixed proportions of ingredients. It could have more or less lemon juice, for example, or more or less sugar, and it would still be lemonade.


Q: In what do substances combine chemically to form a new substance?


A:
compound