Q: A single amino acid substitution in hemoglobin leads to what disease?


Read this paragraph and choose the correct option from the provided answers:

Figure 3.26 The beta chain of hemoglobin is 147 residues in length, yet a single amino acid substitution leads to sickle cell anemia. In normal hemoglobin, the amino acid at position seven is glutamate. In sickle cell hemoglobin, this glutamate is replaced by a valine.

 Choices:

- crohn's disease

- AIDS

- down's syndrome

- sickle cell anemia


A:
sickle cell anemia