Fact 1: Disease has a negative impact on an organism.

Fact 2: Smoking was negatively associated with prevalent Alzheimer's disease and dementia.

Given the two facts above, answer the question "what impact does smoking have?" with the following options: 
- Dehydration
 - good
 - negative
 - dangerous
 - liver cancer
 - healthy
 - wellness
 - cancer


 

   negative      