Daily Papers

Large language models (LLMs) perform well on common tasks but struggle with generalization in low-resource and low-computation settings. We examine this limitation by testing various LLMs and specialized translation models on English-Thai machine translation and code-switching datasets. Our findings reveal that under more strict computational constraints, such as 4-bit quantization, LLMs fail to translate effectively. In contrast, specialized models, with comparable or lower computational requirements, consistently outperform LLMs. This underscores the importance of specialized models for maintaining performance under resource constraints.

Sentiment analysis is a vital tool for uncovering insights from financial articles, news, and social media, shaping our understanding of market movements. Despite the impressive capabilities of large language models (LLMs) in financial natural language processing (NLP), they still struggle with accurately interpreting numerical values and grasping financial context, limiting their effectiveness in predicting financial sentiment. In this paper, we introduce a simple yet effective instruction tuning approach to address these issues. By transforming a small portion of supervised financial sentiment analysis data into instruction data and fine-tuning a general-purpose LLM with this method, we achieve remarkable advancements in financial sentiment analysis. In the experiment, our approach outperforms state-of-the-art supervised sentiment analysis models, as well as widely used LLMs like ChatGPT and LLaMAs, particularly in scenarios where numerical understanding and contextual comprehension are vital.

Generative AI is gaining increasing attention in software engineering, where testing remains an indispensable reliability mechanism. According to the widely adopted testing pyramid, unit tests constitute the majority of test cases and are often schematic, requiring minimal domain expertise. Automatically generating such tests under the supervision of software engineers can significantly enhance productivity during the development phase of the software lifecycle. This paper investigates the impact of code context and prompting strategies on the quality and adequacy of unit tests generated by various large language models (LLMs) across several families. The results show that including docstrings notably improves code adequacy, while further extending context to the full implementation yields definitely smaller gains. Notably, the chain-of-thought prompting strategy -- applied even to 'reasoning' models -- achieves the best results, with up to 96.3\% branch coverage, a 57\% average mutation score, and near-perfect compilation success rate. Among the evaluated models, M5 (Gemini 2.5 Pro) demonstrated superior performance in both mutation score and branch coverage being still in top in terms of compilation success rate. All the code and resulting test suites are publicly available at https://github.com/peetery/LLM-analysis.

We introduce DeSTA2.5-Audio, a general-purpose Large Audio Language Model (LALM) designed for robust auditory perception and instruction-following, without requiring task-specific audio instruction-tuning. Recent LALMs typically augment Large Language Models (LLMs) with auditory capabilities by training on large-scale, manually curated or LLM-synthesized audio-instruction datasets. However, these approaches have often suffered from the catastrophic forgetting of the LLM's original language abilities. To address this, we revisit the data construction pipeline and propose DeSTA, a self-generated cross-modal alignment strategy in which the backbone LLM generates its own training targets. This approach preserves the LLM's native language proficiency while establishing effective audio-text alignment, thereby enabling zero-shot generalization without task-specific tuning. Using DeSTA, we construct DeSTA-AQA5M, a large-scale, task-agnostic dataset containing 5 million training samples derived from 7,000 hours of audio spanning 50 diverse datasets, including speech, environmental sounds, and music. DeSTA2.5-Audio achieves state-of-the-art or competitive performance across a wide range of audio-language benchmarks, including Dynamic-SUPERB, MMAU, SAKURA, Speech-IFEval, and VoiceBench. Comprehensive comparative studies demonstrate that our self-generated strategy outperforms widely adopted data construction and training strategies in both auditory perception and instruction-following capabilities. Our findings underscore the importance of carefully designed data construction in LALM development and offer practical insights for building robust, general-purpose LALMs.

Large language models (LLMs) are increasingly adopted for knowledge-intensive tasks and contexts. Existing approaches improve the knowledge capabilities of general-purpose LLMs through retrieval or generated knowledge prompting, but they fall short of reflecting two key properties of knowledge-rich models: knowledge should be modular, ever-growing, sourced from diverse domains; knowledge acquisition and production should be a collaborative process, where diverse stakeholders contribute new information. To this end, we propose CooK, a novel framework to empower general-purpose large language models with modular and collaboratively sourced knowledge. We first introduce specialized language models, autoregressive models trained on corpora from a wide range of domains and sources. These specialized LMs serve as parametric knowledge repositories that are later prompted to generate background knowledge for general-purpose LLMs. We then propose three knowledge filters to dynamically select and retain information in generated documents by controlling for relevance, brevity, and factuality. Finally, we propose bottom-up and top-down knowledge integration approaches to augment general-purpose LLMs with the curated (relevant, factual) knowledge from community-driven specialized LMs that enable multi-domain knowledge synthesis and on-demand knowledge requests. Through extensive experiments, we demonstrate that CooK achieves state-of-the-art performance on six benchmark datasets. Our results highlight the potential of enriching general-purpose LLMs with evolving and modular knowledge -- relevant knowledge that can be continuously updated through the collective efforts of the research community.

Aligning general-purpose large language models (LLMs) to downstream tasks often incurs significant training adjustment costs. Prior research has explored various avenues to enhance alignment efficiency, primarily through minimal-data training or data-driven activations to identify key attention heads. However, these approaches inherently introduce data dependency, which hinders generalization and reusability. To address this issue and enhance model alignment efficiency, we propose the \textbf{Attention Localization and Pruning Strategy (ALPS)}, an efficient algorithm that localizes the most task-sensitive attention heads and prunes by restricting attention training updates to these heads, thereby reducing alignment costs. Experimental results demonstrate that our method activates only 10\% of attention parameters during fine-tuning while achieving a 2\% performance improvement over baselines on three tasks. Moreover, the identified task-specific heads are transferable across datasets and mitigate knowledge forgetting. Our work and findings provide a novel perspective on efficient LLM alignment. The code is available at https://github.com/VoiceBeer/ALPS.

This paper presents the outcomes of fine-tuning Mistral 7B, a general-purpose large language model (LLM), for adaptive machine translation (MT). The fine-tuning process involves utilising a combination of zero-shot and one-shot translation prompts within the medical domain. The primary objective is to enhance real-time adaptive MT capabilities of Mistral 7B, enabling it to adapt translations to the required domain at inference time. The results, particularly for Spanish-to-English MT, showcase the efficacy of the fine-tuned model, demonstrating quality improvements in both zero-shot and one-shot translation scenarios, surpassing Mistral 7B's baseline performance. Notably, the fine-tuned Mistral outperforms ChatGPT "gpt-3.5-turbo" in zero-shot translation while achieving comparable one-shot translation quality. Moreover, the zero-shot translation of the fine-tuned Mistral matches NLLB 3.3B's performance, and its one-shot translation quality surpasses that of NLLB 3.3B. These findings emphasise the significance of fine-tuning efficient LLMs like Mistral 7B to yield high-quality zero-shot translations comparable to task-oriented models like NLLB 3.3B. Additionally, the adaptive gains achieved in one-shot translation are comparable to those of commercial LLMs such as ChatGPT. Our experiments demonstrate that, with a relatively small dataset of 20,000 segments that incorporate a mix of zero-shot and one-shot prompts, fine-tuning significantly enhances Mistral's in-context learning ability, especially for real-time adaptive MT.

Several recent works seek to develop foundation models specifically for medical applications, adapting general-purpose large language models (LLMs) and vision-language models (VLMs) via continued pretraining on publicly available biomedical corpora. These works typically claim that such domain-adaptive pretraining (DAPT) improves performance on downstream medical tasks, such as answering medical licensing exam questions. In this paper, we compare seven public "medical" LLMs and two VLMs against their corresponding base models, arriving at a different conclusion: all medical VLMs and nearly all medical LLMs fail to consistently improve over their base models in the zero-/few-shot prompting regime for medical question-answering (QA) tasks. For instance, across the tasks and model pairs we consider in the 3-shot setting, medical LLMs only outperform their base models in 12.1% of cases, reach a (statistical) tie in 49.8% of cases, and are significantly worse than their base models in the remaining 38.2% of cases. Our conclusions are based on (i) comparing each medical model head-to-head, directly against the corresponding base model; (ii) optimizing the prompts for each model separately; and (iii) accounting for statistical uncertainty in comparisons. While these basic practices are not consistently adopted in the literature, our ablations show that they substantially impact conclusions. Our findings suggest that state-of-the-art general-domain models may already exhibit strong medical knowledge and reasoning capabilities, and offer recommendations to strengthen the conclusions of future studies.

Large language models (LLMs) have revolutionized Natural Language Processing (NLP) by minimizing the need for complex feature engineering. However, the application of LLMs in specialized domains like biopharmaceuticals and chemistry remains largely unexplored. These fields are characterized by intricate terminologies, specialized knowledge, and a high demand for precision areas where general purpose LLMs often fall short. In this study, we introduce PharmaGPT, a suite of domain specilized LLMs with 13 billion and 70 billion parameters, specifically trained on a comprehensive corpus tailored to the Bio-Pharmaceutical and Chemical domains. Our evaluation shows that PharmaGPT surpasses existing general models on specific-domain benchmarks such as NAPLEX, demonstrating its exceptional capability in domain-specific tasks. Remarkably, this performance is achieved with a model that has only a fraction, sometimes just one-tenth-of the parameters of general-purpose large models. This advancement establishes a new benchmark for LLMs in the bio-pharmaceutical and chemical fields, addressing the existing gap in specialized language modeling. It also suggests a promising path for enhanced research and development, paving the way for more precise and effective NLP applications in these areas.

Several recent works seek to develop foundation models specifically for medical applications, adapting general-purpose large language models (LLMs) and vision-language models (VLMs) via continued pretraining on publicly available biomedical corpora. These works typically claim that such domain-adaptive pretraining (DAPT) improves performance on downstream medical tasks, such as answering medical licensing exam questions. In this paper, we compare ten public "medical" LLMs and two VLMs against their corresponding base models, arriving at a different conclusion: all medical VLMs and nearly all medical LLMs fail to consistently improve over their base models in the zero-/few-shot prompting and supervised fine-tuning regimes for medical question-answering (QA). For instance, across all tasks and model pairs we consider in the 3-shot setting, medical LLMs only outperform their base models in 22.7% of cases, reach a (statistical) tie in 36.8% of cases, and are significantly worse than their base models in the remaining 40.5% of cases. Our conclusions are based on (i) comparing each medical model head-to-head, directly against the corresponding base model; (ii) optimizing the prompts for each model separately in zero-/few-shot prompting; and (iii) accounting for statistical uncertainty in comparisons. While these basic practices are not consistently adopted in the literature, our ablations show that they substantially impact conclusions. Meanwhile, we find that after fine-tuning on specific QA tasks, medical LLMs can show performance improvements, but the benefits do not carry over to tasks based on clinical notes. Our findings suggest that state-of-the-art general-domain models may already exhibit strong medical knowledge and reasoning capabilities, and offer recommendations to strengthen the conclusions of future studies.

Interacting with a software system via a chatbot can be challenging, especially when the chatbot needs to generate API calls, in the right order and with the right parameters, to communicate with the system. API calling in chatbot systems poses significant challenges, particularly in complex, multi-step tasks requiring accurate API selection and execution. We contribute to this domain in three ways: first, by introducing a novel dataset designed to assess models on API function selection, parameter generation, and nested API calls; second, by benchmarking state-of-the-art language models across varying levels of complexity to evaluate their performance in API function generation and parameter accuracy; and third, by proposing an enhanced API routing method that combines general-purpose large language models for API selection with fine-tuned models for parameter generation and some prompt engineering approach. These approaches lead to substantial improvements in handling complex API tasks, offering practical advancements for real-world API-driven chatbot systems.

Scientific literature is growing exponentially, creating a critical bottleneck for researchers to efficiently synthesize knowledge. While general-purpose Large Language Models (LLMs) show potential in text processing, they often fail to capture scientific domain-specific nuances (e.g., technical jargon, methodological rigor) and struggle with complex scientific tasks, limiting their utility for interdisciplinary research. To address these gaps, this paper presents SciGPT, a domain-adapted foundation model for scientific literature understanding and ScienceBench, an open source benchmark tailored to evaluate scientific LLMs. Built on the Qwen3 architecture, SciGPT incorporates three key innovations: (1) low-cost domain distillation via a two-stage pipeline to balance performance and efficiency; (2) a Sparse Mixture-of-Experts (SMoE) attention mechanism that cuts memory consumption by 55\% for 32,000-token long-document reasoning; and (3) knowledge-aware adaptation integrating domain ontologies to bridge interdisciplinary knowledge gaps. Experimental results on ScienceBench show that SciGPT outperforms GPT-4o in core scientific tasks including sequence labeling, generation, and inference. It also exhibits strong robustness in unseen scientific tasks, validating its potential to facilitate AI-augmented scientific discovery.

While general-purpose large language models (LLMs) demonstrate proficiency on multiple tasks within the domain of translation, approaches based on open LLMs are competitive only when specializing on a single task. In this paper, we propose a recipe for tailoring LLMs to multiple tasks present in translation workflows. We perform continued pretraining on a multilingual mixture of monolingual and parallel data, creating TowerBase, followed by finetuning on instructions relevant for translation processes, creating TowerInstruct. Our final model surpasses open alternatives on several tasks relevant to translation workflows and is competitive with general-purpose closed LLMs. To facilitate future research, we release the Tower models, our specialization dataset, an evaluation framework for LLMs focusing on the translation ecosystem, and a collection of model generations, including ours, on our benchmark.

Background: General-purpose large language models that utilize both text and images have not been evaluated on a diverse array of challenging medical cases. Methods: Using 934 cases from the NEJM Image Challenge published between 2005 and 2023, we evaluated the accuracy of the recently released Generative Pre-trained Transformer 4 with Vision model (GPT-4V) compared to human respondents overall and stratified by question difficulty, image type, and skin tone. We further conducted a physician evaluation of GPT-4V on 69 NEJM clinicopathological conferences (CPCs). Analyses were conducted for models utilizing text alone, images alone, and both text and images. Results: GPT-4V achieved an overall accuracy of 61% (95% CI, 58 to 64%) compared to 49% (95% CI, 49 to 50%) for humans. GPT-4V outperformed humans at all levels of difficulty and disagreement, skin tones, and image types; the exception was radiographic images, where performance was equivalent between GPT-4V and human respondents. Longer, more informative captions were associated with improved performance for GPT-4V but similar performance for human respondents. GPT-4V included the correct diagnosis in its differential for 80% (95% CI, 68 to 88%) of CPCs when using text alone, compared to 58% (95% CI, 45 to 70%) of CPCs when using both images and text. Conclusions: GPT-4V outperformed human respondents on challenging medical cases and was able to synthesize information from both images and text, but performance deteriorated when images were added to highly informative text. Overall, our results suggest that multimodal AI models may be useful in medical diagnostic reasoning but that their accuracy may depend heavily on context.

In the field of urban planning, general-purpose large language models often struggle to meet the specific needs of planners. Tasks like generating urban planning texts, retrieving related information, and evaluating planning documents pose unique challenges. To enhance the efficiency of urban professionals and overcome these obstacles, we introduce PlanGPT, the first specialized Large Language Model tailored for urban and spatial planning. Developed through collaborative efforts with institutions like the Chinese Academy of Urban Planning, PlanGPT leverages a customized local database retrieval framework, domain-specific fine-tuning of base models, and advanced tooling capabilities. Empirical tests demonstrate that PlanGPT has achieved advanced performance, delivering responses of superior quality precisely tailored to the intricacies of urban planning.

In this paper, we introduce SCALE, a collaborative framework that connects compact Specialized Translation Models (STMs) and general-purpose Large Language Models (LLMs) as one unified translation engine. By introducing translation from STM into the triplet in-context demonstrations, SCALE unlocks refinement and pivoting ability of LLM, thus mitigating language bias of LLM and parallel data bias of STM, enhancing LLM speciality without sacrificing generality, and facilitating continual learning without expensive LLM fine-tuning. Our comprehensive experiments show that SCALE significantly outperforms both few-shot LLMs (GPT-4) and specialized models (NLLB) in challenging low-resource settings. Moreover, in Xhosa to English translation, SCALE experiences consistent improvement by a 4 BLEURT score without tuning LLM and surpasses few-shot GPT-4 by 2.5 COMET score and 3.8 BLEURT score when equipped with a compact model consisting of merely 600M parameters. SCALE could also effectively exploit the existing language bias of LLMs by using an English-centric STM as a pivot for translation between any language pairs, outperforming few-shot GPT-4 by an average of 6 COMET points across eight translation directions. Furthermore we provide an in-depth analysis of SCALE's robustness, translation characteristics, and latency costs, providing solid foundation for future studies exploring the potential synergy between LLMs and more specialized, task-specific models.

General-purpose Large Language Models (LLMs) have achieved remarkable success in intelligence, performing comparably to human experts on complex reasoning tasks such as coding and mathematical reasoning. However, generating formal proofs in specialized languages like Lean 4 remains a significant challenge for these models, limiting their application in complex theorem proving and automated verification. Current approaches typically require specializing models through fine-tuning on dedicated formal corpora, incurring high costs for data collection and training. In this work, we introduce Delta Prover, an agent-based framework that orchestrates the interaction between a general-purpose LLM and the Lean 4 proof environment. Delta Prover leverages the reflection and reasoning capabilities of general-purpose LLMs to interactively construct formal proofs in Lean 4, circumventing the need for model specialization. At its core, the agent integrates two novel, interdependent components: an algorithmic framework for reflective decomposition and iterative proof repair, and a custom Domain-Specific Language (DSL) built upon Lean 4 for streamlined subproblem management. Delta Prover achieves a state-of-the-art 95.9\% success rate on the miniF2F-test benchmark, surpassing all existing approaches, including those requiring model specialization. Furthermore, Delta Prover exhibits a significantly stronger test-time scaling law compared to standard Best-of-N proof strategies. Crucially, our findings demonstrate that general-purpose LLMs, when guided by an effective agentic structure, possess substantial untapped theorem-proving capabilities. This presents a computationally efficient alternative to specialized models for robust automated reasoning in formal environments.

General-purpose large language models, despite their broad capabilities, often struggle with specialized domain knowledge, a limitation particularly pronounced in more accessible, lower-parameter versions. This gap hinders their deployment as effective agents in demanding fields such as astronomy. Building on our prior work with AstroSage-8B, this study introduces AstroSage-70B, a significantly larger and more advanced domain-specialized natural-language AI assistant. It is designed for research and education across astronomy, astrophysics, space science, astroparticle physics, cosmology, and astronomical instrumentation. Developed from the Llama-3.1-70B foundation, AstroSage-70B underwent extensive continued pre-training on a vast corpus of astronomical literature, followed by supervised fine-tuning and model merging. Beyond its 70-billion parameter scale, this model incorporates refined datasets, judiciously chosen learning hyperparameters, and improved training procedures, achieving state-of-the-art performance on complex astronomical tasks. Notably, we integrated reasoning chains into the SFT dataset, enabling AstroSage-70B to either answer the user query immediately, or first emit a human-readable thought process. Evaluated on the AstroMLab-1 benchmark -- comprising 4,425 questions from literature withheld during training -- AstroSage-70B achieves state-of-the-art performance. It surpasses all other tested open-weight and proprietary models, including leading systems like o3, Gemini-2.5-Pro, Claude-3.7-Sonnet, Deepseek-R1, and Qwen-3-235B, even those with API costs two orders of magnitude higher. This work demonstrates that domain specialization, when applied to large-scale models, can enable them to outperform generalist counterparts in specialized knowledge areas like astronomy, thereby advancing the frontier of AI capabilities in the field.

General-purpose large language models (LLMs), despite their broad capabilities accrued from open-world data, frequently exhibit suboptimal performance when confronted with the nuanced and specialized demands inherent in real-time telecommunications applications. This investigation addresses this critical limitation through the meticulous fine-tuning of TSLAM-Mini developed by NetoAI, a compact (3.8-billion parameter) causal language model architecturally derived from Phi-4 Mini Instruct 4B. The fine-tuning regimen leverages a bespoke dataset comprising 100,000 samples, strategically engineered to address 20 pivotal telecommunications use-cases, encompassing domains such as Network Fundamentals, IP Routing, MPLS, Network Security, Automation, OSS/BSS, RAN, Mobile Core, Satellite Communications, and Ethical AI. This dataset was curated utilizing NetoAI's DigiTwin platform, enriched with granular insights from venerated network Subject Matter Experts (SMEs) and authoritative RFC documents, thereby capturing high-fidelity representations of real-world network dynamics through simulations inspired by digital twin paradigms. Employing Quantized Low-Rank Adaptation (QLoRA), a state-of-the-art Parameter Efficient Fine-Tuning (PEFT) technique, we achieved substantial training efficiency and enabled prospective deployment on resource-constrained hardware. A novel evaluation framework, predicated on a high-capacity LLM (Qwen3-235B-A22B) functioning as an automated adjudicator, was instituted to rigorously assess instruction-following fidelity and response quality across the specified telecom use-cases. Empirical results unequivocally demonstrate TSLAM-Mini's superior aptitude in telecom-centric applications, underscoring the profound efficacy of domain-specific datasets and PEFT methodologies for advancing intelligent network management.

General-purpose Large Language Models (LLMs) like GPT-4 have achieved remarkable advancements in machine translation (MT) by leveraging extensive web content. On the other hand, translation-specific LLMs are built by pre-training on domain-specific monolingual corpora and fine-tuning with human-annotated translation data. Despite the superior performance, these methods either demand an unprecedented scale of computing and data or substantial human editing and annotation efforts. In this paper, we develop MT-Ladder, a novel model-agnostic and cost-effective tool to refine the performance of general LLMs for MT. MT-Ladder is trained on pseudo-refinement triplets which can be easily obtained from existing LLMs without additional human cost. During training, we propose a hierarchical fine-tuning strategy with an easy-to-hard schema, improving MT-Ladder's refining performance progressively. The trained MT-Ladder can be seamlessly integrated with any general-purpose LLMs to boost their translation performance. By utilizing Gemma-2B/7B as the backbone, MT-Ladder-2B can elevate raw translations to the level of top-tier open-source models (e.g., refining BigTranslate-13B with +6.91 BLEU and +3.52 COMET for XX-En), and MT-Ladder-7B can further enhance model performance to be on par with the state-of-the-art GPT-4. Extensive ablation and analysis corroborate the effectiveness of MT-Ladder in diverse settings. Our code is available at https://github.com/fzp0424/Ladder

Current general-purpose large language models (LLMs) commonly exhibit knowledge hallucination and insufficient domain-specific adaptability in domain-specific tasks, limiting their effectiveness in specialized question answering scenarios. Retrieval-augmented generation (RAG) effectively tackles these challenges by integrating external knowledge to enhance accuracy and relevance. However, traditional RAG still faces limitations in domain knowledge accuracy and context modeling.To enhance domain-specific question answering performance, this work focuses on a graph-based RAG framework, emphasizing the critical role of knowledge graph quality during the generation process. We propose DSRAG (Domain-Specific RAG), a multimodal knowledge graph-driven retrieval-augmented generation framework designed for domain-specific applications. Our approach leverages domain-specific documents as the primary knowledge source, integrating heterogeneous information such as text, images, and tables to construct a multimodal knowledge graph covering both conceptual and instance layers. Building on this foundation, we introduce semantic pruning and structured subgraph retrieval mechanisms, combining knowledge graph context and vector retrieval results to guide the language model towards producing more reliable responses. Evaluations using the Langfuse multidimensional scoring mechanism show that our method excels in domain-specific question answering, validating the efficacy of integrating multimodal knowledge graphs with retrieval-augmented generation.

Decoding methods play an indispensable role in converting language models from next-token predictors into practical task solvers. Prior research on decoding methods, primarily focusing on task-specific models, may not extend to the current era of general-purpose large language models (LLMs). Moreover, the recent influx of decoding strategies has further complicated this landscape. This paper provides a comprehensive and multifaceted analysis of various decoding methods within the context of LLMs, evaluating their performance, robustness to hyperparameter changes, and decoding speeds across a wide range of tasks, models, and deployment environments. Our findings reveal that decoding method performance is notably task-dependent and influenced by factors such as alignment, model size, and quantization. Intriguingly, sensitivity analysis exposes that certain methods achieve superior performance at the cost of extensive hyperparameter tuning, highlighting the trade-off between attaining optimal results and the practicality of implementation in varying contexts.

This paper introduces DeepPsy-Agent, an innovative psychological support system that combines the three-stage helping theory in psychology with deep learning techniques. The system consists of two core components: (1) a multi-stage response-capable dialogue model (deeppsy-chat), which enhances reasoning capabilities through stage-awareness and deep-thinking analysis to generate high-quality responses; and (2) a real-time stage transition detection model that identifies contextual shifts to guide the dialogue towards more effective intervention stages. Based on 30,000 real psychological hotline conversations, we employ AI-simulated dialogues and expert re-annotation strategies to construct a high-quality multi-turn dialogue dataset. Experimental results demonstrate that DeepPsy-Agent outperforms general-purpose large language models (LLMs) in key metrics such as problem exposure completeness, cognitive restructuring success rate, and action adoption rate. Ablation studies further validate the effectiveness of stage-awareness and deep-thinking modules, showing that stage information contributes 42.3\% to performance, while the deep-thinking module increases root-cause identification by 58.3\% and reduces ineffective suggestions by 72.1\%. This system addresses critical challenges in AI-based psychological support through dynamic dialogue management and deep reasoning, advancing intelligent mental health services.

Retrieving and extracting knowledge from extensive research documents and large databases presents significant challenges for researchers, students, and professionals in today's information-rich era. Existing retrieval systems, which rely on general-purpose Large Language Models (LLMs), often fail to provide accurate responses to domain-specific inquiries. Additionally, the high cost of pretraining or fine-tuning LLMs for specific domains limits their widespread adoption. To address these limitations, we propose a novel methodology that combines the generative capabilities of LLMs with the fast and accurate retrieval capabilities of vector databases. This advanced retrieval system can efficiently handle both tabular and non-tabular data, understand natural language user queries, and retrieve relevant information without fine-tuning. The developed model, Generative Text Retrieval (GTR), is adaptable to both unstructured and structured data with minor refinement. GTR was evaluated on both manually annotated and public datasets, achieving over 90% accuracy and delivering truthful outputs in 87% of cases. Our model achieved state-of-the-art performance with a Rouge-L F1 score of 0.98 on the MSMARCO dataset. The refined model, Generative Tabular Text Retrieval (GTR-T), demonstrated its efficiency in large database querying, achieving an Execution Accuracy (EX) of 0.82 and an Exact-Set-Match (EM) accuracy of 0.60 on the Spider dataset, using an open-source LLM. These efforts leverage Generative AI and In-Context Learning to enhance human-text interaction and make advanced AI capabilities more accessible. By integrating robust retrieval systems with powerful LLMs, our approach aims to democratize access to sophisticated AI tools, improving the efficiency, accuracy, and scalability of AI-driven information retrieval and database querying.

Low-rank adaptation (LoRA) methods show great potential for scaling pre-trained general-purpose Large Language Models (LLMs) to hundreds or thousands of use scenarios. However, their efficacy in high-stakes domains like finance is rarely explored, e.g., passing CFA exams and analyzing SEC filings. In this paper, we present the open-source FinLoRA project that benchmarks LoRA methods on both general and highly professional financial tasks. First, we curated 19 datasets covering diverse financial applications; in particular, we created four novel XBRL analysis datasets based on 150 SEC filings. Second, we evaluated five LoRA methods and five base LLMs. Finally, we provide extensive experimental results in terms of accuracy, F1, and BERTScore and report computational cost in terms of time and GPU memory during fine-tuning and inference stages. We find that LoRA methods achieved substantial performance gains of 36\% on average over base models. Our FinLoRA project provides an affordable and scalable approach to democratize financial intelligence to the general public. Datasets, LoRA adapters, code, and documentation are available at https://github.com/Open-Finance-Lab/FinLoRA

Sharing methods of attack and their effectiveness is a cornerstone of building robust defensive systems. Threat analysis reports, produced by various individuals and organizations, play a critical role in supporting security operations and combating emerging threats. To enhance the timeliness and automation of threat intelligence sharing, several standards have been established, with the Structured Threat Information Expression (STIX) framework emerging as one of the most widely adopted. However, generating STIX-compatible data from unstructured security text remains a largely manual, expert-driven process. To address this challenge, we introduce AZERG, a tool designed to assist security analysts in automatically generating structured STIX representations. To achieve this, we adapt general-purpose large language models for the specific task of extracting STIX-formatted threat data. To manage the complexity, the task is divided into four subtasks: entity detection (T1), entity type identification (T2), related pair detection (T3), and relationship type identification (T4). We apply task-specific fine-tuning to accurately extract relevant entities and infer their relationships in accordance with the STIX specification. To address the lack of training data, we compiled a comprehensive dataset with 4,011 entities and 2,075 relationships extracted from 141 full threat analysis reports, all annotated in alignment with the STIX standard. Our models achieved F1-scores of 84.43% for T1, 88.49% for T2, 95.47% for T3, and 84.60% for T4 in real-world scenarios. We validated their performance against a range of open- and closed-parameter models, as well as state-of-the-art methods, demonstrating improvements of 2-25% across tasks.

Over the past decade, predictive language modeling for code has proven to be a valuable tool for enabling new forms of automation for developers. More recently, we have seen the advent of general purpose "large language models", based on neural transformer architectures, that have been trained on massive datasets of human written text spanning code and natural language. However, despite the demonstrated representational power of such models, interacting with them has historically been constrained to specific task settings, limiting their general applicability. Many of these limitations were recently overcome with the introduction of ChatGPT, a language model created by OpenAI and trained to operate as a conversational agent, enabling it to answer questions and respond to a wide variety of commands from end users. The introduction of models, such as ChatGPT, has already spurred fervent discussion from educators, ranging from fear that students could use these AI tools to circumvent learning, to excitement about the new types of learning opportunities that they might unlock. However, given the nascent nature of these tools, we currently lack fundamental knowledge related to how well they perform in different educational settings, and the potential promise (or danger) that they might pose to traditional forms of instruction. As such, in this paper, we examine how well ChatGPT performs when tasked with answering common questions in a popular software testing curriculum. Our findings indicate that ChatGPT can provide correct or partially correct answers in 55.6% of cases, provide correct or partially correct explanations of answers in 53.0% of cases, and that prompting the tool in a shared question context leads to a marginally higher rate of correct responses. Based on these findings, we discuss the potential promises and perils related to the use of ChatGPT by students and instructors.

This paper reviews the MARS2 2025 Challenge on Multimodal Reasoning. We aim to bring together different approaches in multimodal machine learning and LLMs via a large benchmark. We hope it better allows researchers to follow the state-of-the-art in this very dynamic area. Meanwhile, a growing number of testbeds have boosted the evolution of general-purpose large language models. Thus, this year's MARS2 focuses on real-world and specialized scenarios to broaden the multimodal reasoning applications of MLLMs. Our organizing team released two tailored datasets Lens and AdsQA as test sets, which support general reasoning in 12 daily scenarios and domain-specific reasoning in advertisement videos, respectively. We evaluated 40+ baselines that include both generalist MLLMs and task-specific models, and opened up three competition tracks, i.e., Visual Grounding in Real-world Scenarios (VG-RS), Visual Question Answering with Spatial Awareness (VQA-SA), and Visual Reasoning in Creative Advertisement Videos (VR-Ads). Finally, 76 teams from the renowned academic and industrial institutions have registered and 40+ valid submissions (out of 1200+) have been included in our ranking lists. Our datasets, code sets (40+ baselines and 15+ participants' methods), and rankings are publicly available on the MARS2 workshop website and our GitHub organization page https://github.com/mars2workshop/, where our updates and announcements of upcoming events will be continuously provided.

As advances in large language models (LLMs) and multimodal techniques continue to mature, the development of general-purpose multimodal large language models (MLLMs) has surged, offering significant applications in interpreting natural images. However, the field of pathology has largely remained untapped, particularly in gathering high-quality data and designing comprehensive model frameworks. To bridge the gap in pathology MLLMs, we present PathAsst, a multimodal generative foundation AI assistant to revolutionize diagnostic and predictive analytics in pathology. The development of PathAsst involves three pivotal steps: data acquisition, CLIP model adaptation, and the training of PathAsst's multimodal generative capabilities. Firstly, we collect over 207K high-quality pathology image-text pairs from authoritative sources. Leveraging the advanced power of ChatGPT, we generate over 180K instruction-following samples. Furthermore, we devise additional instruction-following data specifically tailored for invoking eight pathology-specific sub-models we prepared, allowing the PathAsst to effectively collaborate with these models, enhancing its diagnostic ability. Secondly, by leveraging the collected data, we construct PathCLIP, a pathology-dedicated CLIP, to enhance PathAsst's capabilities in interpreting pathology images. Finally, we integrate PathCLIP with the Vicuna-13b and utilize pathology-specific instruction-tuning data to enhance the multimodal generation capacity of PathAsst and bolster its synergistic interactions with sub-models. The experimental results of PathAsst show the potential of harnessing AI-powered generative foundation model to improve pathology diagnosis and treatment processes.

Toxicity remains a leading cause of early-stage drug development failure. Despite advances in molecular design and property prediction, the task of molecular toxicity repair - generating structurally valid molecular alternatives with reduced toxicity - has not yet been systematically defined or benchmarked. To fill this gap, we introduce ToxiMol, the first benchmark task for general-purpose Multimodal Large Language Models (MLLMs) focused on molecular toxicity repair. We construct a standardized dataset covering 11 primary tasks and 560 representative toxic molecules spanning diverse mechanisms and granularities. We design a prompt annotation pipeline with mechanism-aware and task-adaptive capabilities, informed by expert toxicological knowledge. In parallel, we propose an automated evaluation framework, ToxiEval, which integrates toxicity endpoint prediction, synthetic accessibility, drug-likeness, and structural similarity into a high-throughput evaluation chain for repair success. We systematically assess nearly 30 mainstream general-purpose MLLMs and design multiple ablation studies to analyze key factors such as evaluation criteria, candidate diversity, and failure attribution. Experimental results show that although current MLLMs still face significant challenges on this task, they begin to demonstrate promising capabilities in toxicity understanding, semantic constraint adherence, and structure-aware molecule editing.

Graphical User Interface (GUI) agents aim to automate a wide spectrum of human tasks by emulating user interaction. Despite rapid advancements, current approaches are hindered by several critical challenges: data bottleneck in end-to-end training, high cost of delayed error detection, and risk of contradictory guidance. Inspired by the human cognitive loop of Thinking, Alignment, and Reflection, we present D-Artemis -- a novel deliberative framework in this paper. D-Artemis leverages a fine-grained, app-specific tip retrieval mechanism to inform its decision-making process. It also employs a proactive Pre-execution Alignment stage, where Thought-Action Consistency (TAC) Check module and Action Correction Agent (ACA) work in concert to mitigate the risk of execution failures. A post-execution Status Reflection Agent (SRA) completes the cognitive loop, enabling strategic learning from experience. Crucially, D-Artemis enhances the capabilities of general-purpose Multimodal large language models (MLLMs) for GUI tasks without the need for training on complex trajectory datasets, demonstrating strong generalization. D-Artemis establishes new state-of-the-art (SOTA) results across both major benchmarks, achieving a 75.8% success rate on AndroidWorld and 96.8% on ScreenSpot-V2. Extensive ablation studies further demonstrate the significant contribution of each component to the framework.

Building a general-purpose task model similar to ChatGPT has been an important research direction for gene large language models. Instruction fine-tuning is a key component in building ChatGPT, but existing instructions are primarily based on natural language. Natural language and gene sequences have significant differences in tokenization and encoding. Therefore, constructing a multilingual model that can handle both natural language and gene sequences is crucial for solving this problem.In this paper, we expand the capabilities of the LLaMA large language model to include gene language. This involves expanding the vocabulary using the Byte Pair Encoding (BPE) method, specifically tailored for DNA and protein sequences, and conducting further pre-training on these sequences. We then convert various downstream gene task data into a unified format for instruction fine-tuning and further fine-tune the model on this data.Our study demonstrates that a mixed model of gene and natural language, fine-tuned with instructions, achieves results comparable to the current state-of-the-art (SOTA) in tasks such as gene classification and gene sequence interaction. This provides a promising direction for building a unified large language model for gene tasks.

In this work, we extend the instruction-tuned Llama-2 model with end-to-end general-purpose speech processing and reasoning abilities while maintaining the wide range of LLM capabilities, without using any carefully curated paired data. The proposed model can utilize audio prompts as a replacement for text and sustain a conversation. Such a model also has extended cross-modal capabilities such as being able to perform speech question answering, speech translation, and audio summarization amongst many other closed and open-domain tasks. This is unlike prior approaches in speech, in which LLMs are extended to handle audio for a limited number of pre-designated tasks. Experiments show that our end-to-end approach is on par with or outperforms a cascaded system (speech recognizer + LLM) in terms of modeling the response to a prompt. Furthermore, unlike a cascade, our approach shows the ability to interchange text and audio modalities and utilize the prior context in a conversation to provide better results.

Our approach, which we call Embeddings for Language/Image-aligned X-Rays, or ELIXR, leverages a language-aligned image encoder combined or grafted onto a fixed LLM, PaLM 2, to perform a broad range of tasks. We train this lightweight adapter architecture using images paired with corresponding free-text radiology reports from the MIMIC-CXR dataset. ELIXR achieved state-of-the-art performance on zero-shot chest X-ray (CXR) classification (mean AUC of 0.850 across 13 findings), data-efficient CXR classification (mean AUCs of 0.893 and 0.898 across five findings (atelectasis, cardiomegaly, consolidation, pleural effusion, and pulmonary edema) for 1% (~2,200 images) and 10% (~22,000 images) training data), and semantic search (0.76 normalized discounted cumulative gain (NDCG) across nineteen queries, including perfect retrieval on twelve of them). Compared to existing data-efficient methods including supervised contrastive learning (SupCon), ELIXR required two orders of magnitude less data to reach similar performance. ELIXR also showed promise on CXR vision-language tasks, demonstrating overall accuracies of 58.7% and 62.5% on visual question answering and report quality assurance tasks, respectively. These results suggest that ELIXR is a robust and versatile approach to CXR AI.

Large language models (LLMs) have demonstrated remarkable capabilities in code-related tasks, such as code understanding and code generation. However, an equally important yet underexplored question is whether LLMs can serve as general-purpose surrogate code executors, to predict the output and behavior of a program without actually running it. To systematically investigate this capability, we introduce SURGE, a comprehensive benchmark covering eight key aspects: multi-language programming tasks, competition-level programming problems, repository-level code analysis, high-cost scientific computing, time-complexity-intensive algorithms, buggy code analysis, programs dependent on specific compilers or execution environments, and formal mathematical proof verification. We evaluate multiple open-source and proprietary LLMs on SURGE and conduct a scaling study to analyze the impact of model size and training data scale on surrogate execution accuracy. Additionally, we categorize model prediction errors and explore potential areas for improvement. Our findings indicate that while LLMs can predict code execution results in certain cases, they exhibit limitations in general-purpose surrogate execution. This study provides empirical insights into the feasibility of using LLMs as surrogate code executors. Code and dataset are released at https://github.com/Imbernoulli/SURGE.

Trinity-RFT is a general-purpose, flexible and scalable framework designed for reinforcement fine-tuning (RFT) of large language models. It is built with a decoupled design, consisting of (1) an RFT-core that unifies and generalizes synchronous/asynchronous, on-policy/off-policy, and online/offline modes of RFT, (2) seamless integration for agent-environment interaction with high efficiency and robustness, and (3) systematic data pipelines optimized for RFT. Trinity-RFT can be easily adapted for diverse application scenarios, and serves as a unified platform for exploring advanced reinforcement learning paradigms. This technical report outlines the vision, features, design and implementations of Trinity-RFT, accompanied by extensive examples demonstrating the utility and user-friendliness of the proposed framework.

Pre-training Large Language Models (LLMs) on high-quality, meticulously curated datasets is widely recognized as critical for enhancing their performance and generalization capabilities. This study explores the untapped potential of Common Crawl as a comprehensive and flexible resource for pre-training LLMs, addressing both general-purpose language understanding and specialized domain knowledge. We introduce RedStone, an innovative and scalable pipeline engineered to extract and process data from Common Crawl, facilitating the creation of extensive and varied pre-training datasets. Unlike traditional datasets, which often require expensive curation and domain-specific expertise, RedStone leverages the breadth of Common Crawl to deliver datasets tailored to a wide array of domains. In this work, we exemplify its capability by constructing pre-training datasets across multiple fields, including general language understanding, code, mathematics, and question-answering tasks. The flexibility of RedStone allows for easy adaptation to other specialized domains, significantly lowering the barrier to creating valuable domain-specific datasets. Our findings demonstrate that Common Crawl, when harnessed through effective pipelines like RedStone, can serve as a rich, renewable source of pre-training data, unlocking new avenues for domain adaptation and knowledge discovery in LLMs. This work also underscores the importance of innovative data acquisition strategies and highlights the role of web-scale data as a powerful resource in the continued evolution of LLMs. RedStone code and data samples will be publicly available at https://aka.ms/redstone.

The exponential growth of online textual content across diverse domains has necessitated advanced methods for automated text classification. Large Language Models (LLMs) based on transformer architectures have shown significant success in this area, particularly in natural language processing (NLP) tasks. However, general-purpose LLMs often struggle with domain-specific content, such as scientific texts, due to unique challenges like specialized vocabulary and imbalanced data. In this study, we fine-tune four state-of-the-art LLMs BERT, SciBERT, BioBERT, and BlueBERT on three datasets derived from the WoS-46985 dataset to evaluate their performance in scientific text classification. Our experiments reveal that domain-specific models, particularly SciBERT, consistently outperform general-purpose models in both abstract-based and keyword-based classification tasks. Additionally, we compare our achieved results with those reported in the literature for deep learning models, further highlighting the advantages of LLMs, especially when utilized in specific domains. The findings emphasize the importance of domain-specific adaptations for LLMs to enhance their effectiveness in specialized text classification tasks.

The rapid development in large language models (LLMs) has transformed the landscape of natural language processing and understanding (NLP/NLU), offering significant benefits across various domains. However, when applied to scientific research, these powerful models exhibit critical failure modes related to scientific integrity and trustworthiness. Existing general-purpose LLM guardrails are insufficient to address these unique challenges in the scientific domain. We provide comprehensive guidelines for deploying LLM guardrails in the scientific domain. We identify specific challenges -- including time sensitivity, knowledge contextualization, conflict resolution, and intellectual property concerns -- and propose a guideline framework for the guardrails that can align with scientific needs. These guardrail dimensions include trustworthiness, ethics & bias, safety, and legal aspects. We also outline in detail the implementation strategies that employ white-box, black-box, and gray-box methodologies that can be enforced within scientific contexts.

Recent advancements in Large Language Models (LLMs) have demonstrated their potential in delivering accurate answers to questions about world knowledge. Despite this, existing benchmarks for evaluating LLMs in healthcare predominantly focus on medical doctors, leaving other critical healthcare professions underrepresented. To fill this research gap, we introduce the Examinations for Medical Personnel in Chinese (EMPEC), a pioneering large-scale healthcare knowledge benchmark in traditional Chinese. EMPEC consists of 157,803 exam questions across 124 subjects and 20 healthcare professions, including underrepresented occupations like Optometrists and Audiologists. Each question is tagged with its release time and source, ensuring relevance and authenticity. We conducted extensive experiments on 17 LLMs, including proprietary, open-source models, general domain models and medical specific models, evaluating their performance under various settings. Our findings reveal that while leading models like GPT-4 achieve over 75\% accuracy, they still struggle with specialized fields and alternative medicine. Surprisingly, general-purpose LLMs outperformed medical-specific models, and incorporating EMPEC's training data significantly enhanced performance. Additionally, the results on questions released after the models' training cutoff date were consistent with overall performance trends, suggesting that the models' performance on the test set can predict their effectiveness in addressing unseen healthcare-related queries. The transition from traditional to simplified Chinese characters had a negligible impact on model performance, indicating robust linguistic versatility. Our study underscores the importance of expanding benchmarks to cover a broader range of healthcare professions to better assess the applicability of LLMs in real-world healthcare scenarios.

The advent of large language models marks a revolutionary breakthrough in artificial intelligence. With the unprecedented scale of training and model parameters, the capability of large language models has been dramatically improved, leading to human-like performances in understanding, language synthesizing, and common-sense reasoning, etc. Such a major leap-forward in general AI capacity will change the pattern of how personalization is conducted. For one thing, it will reform the way of interaction between humans and personalization systems. Instead of being a passive medium of information filtering, large language models present the foundation for active user engagement. On top of such a new foundation, user requests can be proactively explored, and user's required information can be delivered in a natural and explainable way. For another thing, it will also considerably expand the scope of personalization, making it grow from the sole function of collecting personalized information to the compound function of providing personalized services. By leveraging large language models as general-purpose interface, the personalization systems may compile user requests into plans, calls the functions of external tools to execute the plans, and integrate the tools' outputs to complete the end-to-end personalization tasks. Today, large language models are still being developed, whereas the application in personalization is largely unexplored. Therefore, we consider it to be the right time to review the challenges in personalization and the opportunities to address them with LLMs. In particular, we dedicate this perspective paper to the discussion of the following aspects: the development and challenges for the existing personalization system, the newly emerged capabilities of large language models, and the potential ways of making use of large language models for personalization.

The rapid evolution of Large Language Models (LLMs) offers promising potential to alleviate the global scarcity of mental health professionals. However, LLMs' alignment with essential mental health counseling competencies remains understudied. We introduce CounselingBench, a novel NCMHCE-based benchmark evaluating LLMs across five key mental health counseling competencies. Testing 22 general-purpose and medical-finetuned LLMs, we find frontier models exceed minimum thresholds but fall short of expert-level performance, with significant variations: they excel in Intake, Assessment & Diagnosis yet struggle with Core Counseling Attributes and Professional Practice & Ethics. Medical LLMs surprisingly underperform generalist models accuracy-wise, while at the same time producing slightly higher-quality justifications but making more context-related errors. Our findings highlight the complexities of developing AI systems for mental health counseling, particularly for competencies requiring empathy and contextual understanding. We found that frontier LLMs perform at a level exceeding the minimal required level of aptitude for all key mental health counseling competencies, but fall short of expert-level performance, and that current medical LLMs do not significantly improve upon generalist models in mental health counseling competencies. This underscores the critical need for specialized, mental health counseling-specific fine-tuned LLMs that rigorously aligns with core competencies combined with appropriate human supervision before any responsible real-world deployment can be considered.

Data-driven techniques have a large potential to transform and accelerate the chemical sciences. However, chemical sciences also pose the unique challenge of very diverse, small, fuzzy datasets that are difficult to leverage in conventional machine learning approaches completely. A new class of models, general-purpose models (GPMs) such as large language models, have shown the ability to solve tasks they have not been directly trained on, and to flexibly operate with low amounts of data in different formats. In this review, we discuss fundamental building principles of GPMs and review recent applications of those models in the chemical sciences across the entire scientific process. While many of these applications are still in the prototype phase, we expect that the increasing interest in GPMs will make many of them mature in the coming years.

The globalization of social interactions has heightened the need for machine translation (MT) on Social Network Services (SNS), yet traditional models struggle with culturally nuanced content like memes, slang, and pop culture references. While large language models (LLMs) have advanced general-purpose translation, their performance on SNS-specific content remains limited due to insufficient specialized training data and evaluation benchmarks. This paper introduces RedTrans, a 72B LLM tailored for SNS translation, trained on a novel dataset developed through three innovations: (1) Supervised Finetuning with Dual-LLM Back-Translation Sampling, an unsupervised sampling method using LLM-based back-translation to select diverse data for large-scale finetuning; (2) Rewritten Preference Optimization (RePO), an algorithm that identifies and corrects erroneous preference pairs through expert annotation, building reliable preference corpora; and (3) RedTrans-Bench, the first benchmark for SNS translation, evaluating phenomena like humor localization, emoji semantics, and meme adaptation. Experiments show RedTrans outperforms state-of-the-art LLMs. Besides, RedTrans has already been deployed in a real-world production environment, demonstrating that domain-specific adaptation, effectively bridges the gap between generic and culturally grounded translation systems.

Academic writing requires both coherent text generation and precise citation of relevant literature. Although recent Retrieval-Augmented Generation (RAG) systems have significantly improved factual accuracy in general-purpose text generation, their capacity to adequately support professional academic writing remains limited. In this work, we introduce ScholarCopilot, a unified framework designed to enhance existing large language models for generating professional academic articles with accurate and contextually relevant citations. ScholarCopilot dynamically determines when to retrieve scholarly references by generating a retrieval token [RET], and then utilizes its representation to look up relevant citations from a database. The retrieved references are fed into the model to augment the generation process. We jointly optimize both the generation and citation tasks within a single framework to increase efficiency. Trained on 500K papers from arXiv, our model achieves a top-1 retrieval accuracy of 40.1% on our evaluation dataset, outperforming baselines such as E5-Mistral-7B-Instruct (15.0%) and BM25 (9.8%). On a dataset of 1,000 academic writing samples, ScholarCopilot scores 16.2/25 in generation quality (measured across relevance, coherence, academic rigor, completeness, and innovation), surpassing models with 10x more parameters such as Qwen-2.5-72B-Instruct (15.8/25). Human studies also confirm ScholarCopilot's superior performance in citation recall, writing efficiency, and overall user experience, confirming the effectiveness of our approach.

Construction of a general-purpose post-recognition error corrector poses a crucial question: how can we most effectively train a model on a large mixture of domain datasets? The answer would lie in learning dataset-specific features and digesting their knowledge in a single model. Previous methods achieve this by having separate correction language models, resulting in a significant increase in parameters. In this work, we present Mixture-of-Experts as a solution, highlighting that MoEs are much more than a scalability tool. We propose a Multi-Task Correction MoE, where we train the experts to become an ``expert'' of speech-to-text, language-to-text and vision-to-text datasets by learning to route each dataset's tokens to its mapped expert. Experiments on the Open ASR Leaderboard show that we explore a new state-of-the-art performance by achieving an average relative 5.0% WER reduction and substantial improvements in BLEU scores for speech and translation tasks. On zero-shot evaluation, NeKo outperforms GPT-3.5 and Claude-Opus with 15.5% to 27.6% relative WER reduction in the Hyporadise benchmark. NeKo performs competitively on grammar and post-OCR correction as a multi-task model.

Large Language Models (LLMs) have drawn a lot of attention due to their strong performance on a wide range of natural language tasks, since the release of ChatGPT in November 2022. LLMs' ability of general-purpose language understanding and generation is acquired by training billions of model's parameters on massive amounts of text data, as predicted by scaling laws kaplan2020scaling,hoffmann2022training. The research area of LLMs, while very recent, is evolving rapidly in many different ways. In this paper, we review some of the most prominent LLMs, including three popular LLM families (GPT, LLaMA, PaLM), and discuss their characteristics, contributions and limitations. We also give an overview of techniques developed to build, and augment LLMs. We then survey popular datasets prepared for LLM training, fine-tuning, and evaluation, review widely used LLM evaluation metrics, and compare the performance of several popular LLMs on a set of representative benchmarks. Finally, we conclude the paper by discussing open challenges and future research directions.

Foundation models of time series have not been fully developed due to the limited availability of time series corpora and the underexploration of scalable pre-training. Based on the similar sequential formulation of time series and natural language, increasing research demonstrates the feasibility of leveraging large language models (LLM) for time series. Nevertheless, the inherent autoregressive property and decoder-only architecture of LLMs have not been fully considered, resulting in insufficient utilization of LLM abilities. To fully revitalize the general-purpose token transition and multi-step generation capability of large language models, we propose AutoTimes to repurpose LLMs as autoregressive time series forecasters, which projects time series into the embedding space of language tokens and autoregressively generates future predictions with arbitrary lengths. Compatible with any decoder-only LLMs, the consequent forecaster exhibits the flexibility of the lookback length and scalability with larger LLMs. Further, we formulate time series as prompts, extending the context for prediction beyond the lookback window, termed in-context forecasting. By introducing LLM-embedded textual timestamps, AutoTimes can utilize chronological information to align multivariate time series. Empirically, AutoTimes achieves state-of-the-art with 0.1% trainable parameters and over 5times training/inference speedup compared to advanced LLM-based forecasters. Code is available at this repository: https://github.com/thuml/AutoTimes.

As large language models (LLMs) increasingly interact with external tools, reward modeling for tool use has become a critical yet underexplored area. Existing reward models, trained primarily on natural language outputs, struggle to evaluate tool-based reasoning and execution. To quantify this gap, we introduce FC-RewardBench, the first benchmark designed to systematically assess reward models' performance in tool-calling scenarios. Our analysis shows that current reward models often miss key signals of effective tool use, highlighting the need for domain-specific modeling. To address this, we propose a training framework for outcome-based reward models using data synthesized from permissively licensed, open-weight LLMs. We train models ranging from 1.7B to 14B parameters and evaluate them across seven out-of-domain benchmarks. These models consistently outperform general-purpose baselines, achieving up to 25\% average improvement in downstream task performance and enabling data-efficient fine-tuning through reward-guided filtering.

The rapid advancement of Large Language Models (LLMs) has established language as a core general-purpose cognitive substrate, driving the demand for specialized Language Processing Units (LPUs) tailored for LLM inference. To overcome the growing energy consumption of LLM inference systems, this paper proposes a Hardwired-Neurons Language Processing Unit (HNLPU), which physically hardwires LLM weight parameters into the computational fabric, achieving several orders of magnitude computational efficiency improvement by extreme specialization. However, a significant challenge still lies in the scale of modern LLMs. An ideal estimation on hardwiring gpt-oss 120 B requires fabricating at least 6 billion dollars of photomask sets, rendering the straightforward solution economically impractical. Addressing this challenge, we propose the novel Metal-Embedding methodology. Instead of embedding weights in a 2D grid of silicon device cells, Metal-Embedding embeds weight parameters into the 3D topology of metal wires. This brings two benefits: (1) a 15x increase in density, and (2) 60 out of 70 layers of photomasks are made homogeneous across chips, including all EUV photomasks. In total, Metal-Embedding reduced the photomask cost by 112x, bringing the Non-Recurring Engineering (NRE) cost of HNLPU into an economically viable range. Experimental results show that HNLPU achieved 249,960 tokens/s (5,555x/85x of GPU/WSE), 36 tokens/J (1,047x/283x of GPU/WSE), 13,232 mm2 total die area (29% inscribed rectangular area in a 300 mm wafer), \$184M estimated NRE at 5 nm technology. Analysis shows that HNLPU achieved 8.57x cost-effectiveness and 230x carbon footprint reduction compared to H100 clusters, under an annual weight updating assumption.

Recent advances in Multimodal Large Language Models (MLLMs) have significantly pushed the frontier of egocentric video question answering (EgocentricQA). However, existing benchmarks and studies are mainly limited to common daily activities such as cooking and cleaning. In contrast, real-world deployment inevitably encounters domain shifts, where target domains differ substantially in both visual style and semantic content. To bridge this gap, we introduce EgoCross, a comprehensive benchmark designed to evaluate the cross-domain generalization of MLLMs in EgocentricQA. EgoCross covers four diverse and challenging domains, including surgery, industry, extreme sports, and animal perspective, representing realistic and high-impact application scenarios. It comprises approximately 1,000 QA pairs across 798 video clips, spanning four key QA tasks: prediction, recognition, localization, and counting. Each QA pair provides both OpenQA and CloseQA formats to support fine-grained evaluation. Extensive experiments show that most existing MLLMs, whether general-purpose or egocentric-specialized, struggle to generalize to domains beyond daily life, highlighting the limitations of current models. Furthermore, we conduct several pilot studies, \eg, fine-tuning and reinforcement learning, to explore potential improvements. We hope EgoCross and our accompanying analysis will serve as a foundation for advancing domain-adaptive, robust egocentric video understanding. Data and codes will be released at: https://github.com/MyUniverse0726/EgoCross{https://github.com/MyUniverse0726/EgoCross.}

Multimodal large language models (MLLMs) are critical for developing general-purpose AI assistants, yet they face growing safety risks. How can we ensure that MLLMs are safely aligned to prevent undesired behaviors such as discrimination, misinformation, or violations of ethical standards? In a further step, we need to explore how to fine-tune MLLMs to enhance reasoning performance while ensuring they satisfy safety constraints. Fundamentally, this can be formulated as a min-max optimization problem. In this study, we propose Safe RLHF-V, the first multimodal safety alignment framework that jointly optimizes helpfulness and safety using separate multimodal reward and cost models within a Lagrangian-based constrained optimization framework. Given that there is a lack of preference datasets that separate helpfulness and safety in multimodal scenarios, we introduce BeaverTails-V, the first open-source dataset with dual preference annotations for helpfulness and safety, along with multi-level safety labels (minor, moderate, severe). Additionally, we design a Multi-level Guardrail System to proactively defend against unsafe queries and adversarial attacks. By applying the Beaver-Guard-V moderation for 5 rounds of filtering and re-generation on the precursor model, the overall safety of the upstream model is significantly improved by an average of 40.9%. Experimental results demonstrate that fine-tuning different MLLMs with Safe RLHF can effectively enhance model helpfulness while ensuring improved safety. Specifically, Safe RLHF-V improves model safety by 34.2% and helpfulness by 34.3%. All of datasets, models, and code can be found at https://github.com/SafeRLHF-V to support the safety development of MLLMs and reduce potential societal risks.

Recent large language models (LLMs) have demonstrated exceptional performance on general-purpose text embedding tasks. While dense embeddings have dominated related research, we introduce the first Lexicon-based EmbeddiNgS (LENS) leveraging LLMs that achieve competitive performance on these tasks. Regarding the inherent tokenization redundancy issue and unidirectional attention limitations in traditional causal LLMs, LENS consolidates the vocabulary space through token embedding clustering, and investigates bidirectional attention and various pooling strategies. Specifically, LENS simplifies lexicon matching by assigning each dimension to a specific token cluster, where semantically similar tokens are grouped together, and unlocking the full potential of LLMs through bidirectional attention. Extensive experiments demonstrate that LENS outperforms dense embeddings on the Massive Text Embedding Benchmark (MTEB), delivering compact feature representations that match the sizes of dense counterparts. Notably, combining LENSE with dense embeddings achieves state-of-the-art performance on the retrieval subset of MTEB (i.e. BEIR).

Scientific Large Language Models (Sci-LLMs) are transforming how knowledge is represented, integrated, and applied in scientific research, yet their progress is shaped by the complex nature of scientific data. This survey presents a comprehensive, data-centric synthesis that reframes the development of Sci-LLMs as a co-evolution between models and their underlying data substrate. We formulate a unified taxonomy of scientific data and a hierarchical model of scientific knowledge, emphasizing the multimodal, cross-scale, and domain-specific challenges that differentiate scientific corpora from general natural language processing datasets. We systematically review recent Sci-LLMs, from general-purpose foundations to specialized models across diverse scientific disciplines, alongside an extensive analysis of over 270 pre-/post-training datasets, showing why Sci-LLMs pose distinct demands -- heterogeneous, multi-scale, uncertainty-laden corpora that require representations preserving domain invariance and enabling cross-modal reasoning. On evaluation, we examine over 190 benchmark datasets and trace a shift from static exams toward process- and discovery-oriented assessments with advanced evaluation protocols. These data-centric analyses highlight persistent issues in scientific data development and discuss emerging solutions involving semi-automated annotation pipelines and expert validation. Finally, we outline a paradigm shift toward closed-loop systems where autonomous agents based on Sci-LLMs actively experiment, validate, and contribute to a living, evolving knowledge base. Collectively, this work provides a roadmap for building trustworthy, continually evolving artificial intelligence (AI) systems that function as a true partner in accelerating scientific discovery.

The rapid evolution of Multi-modality Large Language Models (MLLMs) has catalyzed a shift in computer vision from specialized models to general-purpose foundation models. Nevertheless, there is still an inadequacy in assessing the abilities of MLLMs on low-level visual perception and understanding. To address this gap, we present Q-Bench, a holistic benchmark crafted to systematically evaluate potential abilities of MLLMs on three realms: low-level visual perception, low-level visual description, and overall visual quality assessment. a) To evaluate the low-level perception ability, we construct the LLVisionQA dataset, consisting of 2,990 diverse-sourced images, each equipped with a human-asked question focusing on its low-level attributes. We then measure the correctness of MLLMs on answering these questions. b) To examine the description ability of MLLMs on low-level information, we propose the LLDescribe dataset consisting of long expert-labelled golden low-level text descriptions on 499 images, and a GPT-involved comparison pipeline between outputs of MLLMs and the golden descriptions. c) Besides these two tasks, we further measure their visual quality assessment ability to align with human opinion scores. Specifically, we design a softmax-based strategy that enables MLLMs to predict quantifiable quality scores, and evaluate them on various existing image quality assessment (IQA) datasets. Our evaluation across the three abilities confirms that MLLMs possess preliminary low-level visual skills. However, these skills are still unstable and relatively imprecise, indicating the need for specific enhancements on MLLMs towards these abilities. We hope that our benchmark can encourage the research community to delve deeper to discover and enhance these untapped potentials of MLLMs. Project Page: https://vqassessment.github.io/Q-Bench.

Fine-tuning large language models (LLMs) for telecom tasks and datasets is a common practice to adapt general-purpose models to the telecom domain. However, little attention has been paid to how this process may compromise model safety. Recent research has shown that even benign fine-tuning can degrade the safety alignment of LLMs, causing them to respond to harmful or unethical user queries. In this paper, we investigate this issue for telecom-tuned LLMs using three representative datasets featured by the GenAINet initiative. We show that safety degradation persists even for structured and seemingly harmless datasets such as 3GPP standards and tabular records, indicating that telecom-specific data is not immune to safety erosion during fine-tuning. We further extend our analysis to publicly available Telecom LLMs trained via continual pre-training, revealing that safety alignment is often severely lacking, primarily due to the omission of safety-focused instruction tuning. To address these issues in both fine-tuned and pre-trained models, we conduct extensive experiments and evaluate three safety realignment defenses (SafeInstruct, SafeLoRA, and SafeMERGE) using established red-teaming benchmarks. The results show that, across all settings, the proposed defenses can effectively restore safety after harmful degradation without compromising downstream task performance, leading to Safe teleCOMMunication (SafeCOMM) models. In a nutshell, our work serves as a diagnostic study and practical guide for safety realignment in telecom-tuned LLMs, and emphasizes the importance of safety-aware instruction and fine-tuning for real-world deployments of Telecom LLMs.

Brief hospital course (BHC) summaries are common clinical documents generated by summarizing clinical notes. While large language models (LLMs) depict remarkable capabilities in automating real-world tasks, their capabilities for healthcare applications such as BHC synthesis have not been shown. To enable the adaptation of LLMs for BHC synthesis, we introduce a novel benchmark consisting of a pre-processed dataset extracted from MIMIC-IV notes, encapsulating clinical note, and brief hospital course (BHC) pairs. We assess the performance of two general-purpose LLMs and three healthcare-adapted LLMs to improve BHC synthesis from clinical notes. Using clinical notes as input for generating BHCs, we apply prompting-based (using in-context learning) and fine-tuning-based adaptation strategies to three open-source LLMs (Clinical-T5-Large, Llama2-13B, FLAN-UL2) and two proprietary LLMs (GPT-3.5, GPT-4). We quantitatively evaluate the performance of these LLMs across varying context-length inputs using conventional natural language similarity metrics. We further perform a qualitative study where five diverse clinicians blindly compare clinician-written BHCs and two LLM-generated BHCs for 30 samples across metrics of comprehensiveness, conciseness, factual correctness, and fluency. Overall, we present a new benchmark and pre-processed dataset for using LLMs in BHC synthesis from clinical notes. We observe high-quality summarization performance for both in-context proprietary and fine-tuned open-source LLMs using both quantitative metrics and a qualitative clinical reader study. We propose our work as a benchmark to motivate future works to adapt and assess the performance of LLMs in BHC synthesis.

Large language models (LLMs) have shown remarkable capabilities in language understanding and generation. However, such impressive capability typically comes with a substantial model size, which presents significant challenges in both the deployment, inference, and training stages. With LLM being a general-purpose task solver, we explore its compression in a task-agnostic manner, which aims to preserve the multi-task solving and language generation ability of the original LLM. One challenge to achieving this is the enormous size of the training corpus of LLM, which makes both data transfer and model post-training over-burdensome. Thus, we tackle the compression of LLMs within the bound of two constraints: being task-agnostic and minimizing the reliance on the original training dataset. Our method, named LLM-Pruner, adopts structural pruning that selectively removes non-critical coupled structures based on gradient information, maximally preserving the majority of the LLM's functionality. To this end, the performance of pruned models can be efficiently recovered through tuning techniques, LoRA, in merely 3 hours, requiring only 50K data. We validate the LLM-Pruner on three LLMs, including LLaMA, Vicuna, and ChatGLM, and demonstrate that the compressed models still exhibit satisfactory capabilities in zero-shot classification and generation. The code is available at: https://github.com/horseee/LLM-Pruner

The emergence of large language models (LLMs) has significantly impacted various fields, from natural language processing to sectors like medicine and finance. However, despite their rapid proliferation, the applications of LLMs in telecommunications remain limited, often relying on general-purpose models that lack domain-specific specialization. This lack of specialization results in underperformance, particularly when dealing with telecommunications-specific technical terminology and their associated mathematical representations. This paper addresses this gap by first creating and disseminating Tele-Data, a comprehensive dataset of telecommunications material curated from relevant sources, and Tele-Eval, a large-scale question-and-answer dataset tailored to the domain. Through extensive experiments, we explore the most effective training techniques for adapting LLMs to the telecommunications domain, ranging from examining the division of expertise across various telecommunications aspects to employing parameter-efficient techniques. We also investigate how models of different sizes behave during adaptation and analyze the impact of their training data on this behavior. Leveraging these findings, we develop and open-source Tele-LLMs, the first series of language models ranging from 1B to 8B parameters, specifically tailored for telecommunications. Our evaluations demonstrate that these models outperform their general-purpose counterparts on Tele-Eval while retaining their previously acquired capabilities, thus avoiding the catastrophic forgetting phenomenon.

The ability of large language models (LLMs) to process visual inputs has given rise to general-purpose vision systems, unifying various vision-language (VL) tasks by instruction tuning. However, due to the enormous diversity in input-output formats in the vision domain, existing general-purpose models fail to successfully integrate segmentation and multi-image inputs with coarse-level tasks into a single framework. In this work, we introduce VistaLLM, a powerful visual system that addresses coarse- and fine-grained VL tasks over single and multiple input images using a unified framework. VistaLLM utilizes an instruction-guided image tokenizer that filters global embeddings using task descriptions to extract compressed and refined features from numerous images. Moreover, VistaLLM employs a gradient-aware adaptive sampling technique to represent binary segmentation masks as sequences, significantly improving over previously used uniform sampling. To bolster the desired capability of VistaLLM, we curate CoinIt, a comprehensive coarse-to-fine instruction tuning dataset with 6.8M samples. We also address the lack of multi-image grounding datasets by introducing a novel task, AttCoSeg (Attribute-level Co-Segmentation), which boosts the model's reasoning and grounding capability over multiple input images. Extensive experiments on a wide range of V- and VL tasks demonstrate the effectiveness of VistaLLM by achieving consistent state-of-the-art performance over strong baselines across all downstream tasks. Our project page can be found at https://shramanpramanick.github.io/VistaLLM/.

Rebuses are puzzles requiring constrained multi-step reasoning to identify a hidden phrase from a set of images and letters. In this work, we introduce a large collection of verbalized rebuses for the Italian language and use it to assess the rebus-solving capabilities of state-of-the-art large language models. While general-purpose systems such as LLaMA-3 and GPT-4o perform poorly on this task, ad-hoc fine-tuning seems to improve models' performance. However, we find that performance gains from training are largely motivated by memorization. Our results suggest that rebus solving remains a challenging test bed to evaluate large language models' linguistic proficiency and sequential instruction-following skills.

Large language models (LLMs) face significant challenges stemming from the inherent limitations in knowledge, memory, alignment, and action. These challenges cannot be addressed by LLMs alone, but should rely on assistance from the external world, such as knowledge base, memory store, demonstration examples, and tools. Retrieval augmentation stands as a vital mechanism for bridging the gap between LLMs and the external assistance. However, conventional methods encounter two pressing issues. On one hand, the general-purpose retrievers are not properly optimized for the retrieval augmentation of LLMs. On the other hand, the task-specific retrievers lack the required versatility, hindering their performance across the diverse retrieval augmentation scenarios. In this work, we present a novel approach, the LLM Embedder, which comprehensively support the diverse needs of LLMs' retrieval augmentation with one unified embedding model. Training such an unified model is non-trivial, as various retrieval tasks aim to capture distinct semantic relationships, often subject to mutual interference. To address this challenge, we systematically optimize our training methodology. This includes reward formulation based on LLMs' feedback, the stabilization of knowledge distillation, multi-task fine-tuning with explicit instructions, and the use of homogeneous in-batch negative sampling. These optimization strategies contribute to the outstanding empirical performance of the LLM-Embedder. Notably, it yields remarkable enhancements in retrieval augmentation for LLMs, surpassing both general-purpose and task-specific retrievers in various evaluation scenarios. This project is made publicly available at https://github.com/FlagOpen/FlagEmbedding.

Large Language Models (LLMs) have demonstrated remarkable success in various tasks such as natural language understanding, text summarization, and machine translation. However, their general-purpose nature often limits their effectiveness in domain-specific applications that require specialized knowledge, such as healthcare, chemistry, or legal analysis. To address this, researchers have explored diverse methods to enhance LLMs by integrating domain-specific knowledge. In this survey, we provide a comprehensive overview of these methods, which we categorize into four key approaches: dynamic knowledge injection, static knowledge embedding, modular adapters, and prompt optimization. Each approach offers unique mechanisms to equip LLMs with domain expertise, balancing trade-offs between flexibility, scalability, and efficiency. We discuss how these methods enable LLMs to tackle specialized tasks, compare their advantages and disadvantages, evaluate domain-specific LLMs against general LLMs, and highlight the challenges and opportunities in this emerging field. For those interested in delving deeper into this area, we also summarize the commonly used datasets and benchmarks. To keep researchers updated on the latest studies, we maintain an open-source at: https://github.com/abilliyb/Knowledge_Injection_Survey_Papers, dedicated to documenting research in the field of specialized LLM.

The increasing adoption of artificial intelligence in telecommunications has raised interest in the capability of Large Language Models (LLMs) to address domain-specific, mathematically intensive tasks. Although recent advancements have improved the performance of LLMs in general mathematical reasoning, their effectiveness within specialized domains, such as signal processing, network optimization, and performance analysis, remains largely unexplored. To address this gap, we introduce TeleMath, the first benchmark dataset specifically designed to evaluate LLM performance in solving mathematical problems with numerical solutions in the telecommunications domain. Comprising 500 question-answer (QnA) pairs, TeleMath covers a wide spectrum of topics in the telecommunications field. This paper outlines the proposed QnAs generation pipeline, starting from a selected seed of problems crafted by Subject Matter Experts. The evaluation of a wide range of open-source LLMs reveals that best performance on TeleMath is achieved by recent models explicitly designed for mathematical or logical reasoning. In contrast, general-purpose models, even those with a large number of parameters, often struggle with these challenges. We have released the dataset and the evaluation code to ease result reproducibility and support future research.

In the ongoing wave of impact driven by large language models (LLMs) like ChatGPT, the adaptation of LLMs to medical domain has emerged as a crucial research frontier. Since mainstream LLMs tend to be designed for general-purpose applications, constructing a medical LLM through domain adaptation is a huge challenge. While instruction-tuning is used to fine-tune some LLMs, its precise roles in domain adaptation remain unknown. Here we show the contribution of LoRA-based instruction-tuning to performance in Japanese medical question-answering tasks. In doing so, we employ a multifaceted evaluation for multiple-choice questions, including scoring based on "Exact match" and "Gestalt distance" in addition to the conventional accuracy. Our findings suggest that LoRA-based instruction-tuning can partially incorporate domain-specific knowledge into LLMs, with larger models demonstrating more pronounced effects. Furthermore, our results underscore the potential of adapting English-centric models for Japanese applications in domain adaptation, while also highlighting the persisting limitations of Japanese-centric models. This initiative represents a pioneering effort in enabling medical institutions to fine-tune and operate models without relying on external services.

Large language models (LLMs) hold great promise for medical applications and are evolving rapidly, with new models being released at an accelerated pace. However, current evaluations of LLMs in clinical contexts remain limited. Most existing benchmarks rely on medical exam-style questions or PubMed-derived text, failing to capture the complexity of real-world electronic health record (EHR) data. Others focus narrowly on specific application scenarios, limiting their generalizability across broader clinical use. To address this gap, we present BRIDGE, a comprehensive multilingual benchmark comprising 87 tasks sourced from real-world clinical data sources across nine languages. We systematically evaluated 52 state-of-the-art LLMs (including DeepSeek-R1, GPT-4o, Gemini, and Llama 4) under various inference strategies. With a total of 13,572 experiments, our results reveal substantial performance variation across model sizes, languages, natural language processing tasks, and clinical specialties. Notably, we demonstrate that open-source LLMs can achieve performance comparable to proprietary models, while medically fine-tuned LLMs based on older architectures often underperform versus updated general-purpose models. The BRIDGE and its corresponding leaderboard serve as a foundational resource and a unique reference for the development and evaluation of new LLMs in real-world clinical text understanding.

Large language models (LLMs) have shown exceptional performance as general-purpose assistants, excelling across a variety of reasoning tasks. This achievement represents a significant step toward achieving artificial general intelligence (AGI). Despite these advancements, the effectiveness of LLMs often hinges on the specific prompting strategies employed, and there remains a lack of a robust framework to facilitate learning and generalization across diverse reasoning tasks. To address these challenges, we introduce a novel learning framework, THOUGHT-LIKE-PRO In this framework, we utilize imitation learning to imitate the Chain-of-Thought (CoT) process which is verified and translated from reasoning trajectories generated by a symbolic Prolog logic engine. This framework proceeds in a self-driven manner, that enables LLMs to formulate rules and statements from given instructions and leverage the symbolic Prolog engine to derive results. Subsequently, LLMs convert Prolog-derived successive reasoning trajectories into natural language CoT for imitation learning. Our empirical findings indicate that our proposed approach substantially enhances the reasoning abilities of LLMs and demonstrates robust generalization across out-of-distribution reasoning tasks.

With reasoning language models such as OpenAI-o3 and DeepSeek-R1 emerging, large language models (LLMs) have entered a new phase of development. However, existing benchmarks for coding evaluation are gradually inadequate to assess the capability of advanced LLMs in code reasoning. To bridge the gap for high-level code reasoning assessment, we propose ProBench to benchmark LLMs in competitive programming, drawing inspiration from the International Collegiate Programming Contest. ProBench collects a comprehensive set of competitive programming problems from Codeforces, Luogu, and Nowcoder platforms during the period from July to December 2024, obtaining real test results through online submissions to ensure the fairness and accuracy of the evaluation. We establish a unified problem attribute system, including difficulty grading and algorithm tagging. With carefully collected and annotated data in ProBench, we systematically assess 9 latest LLMs in competitive programming across multiple dimensions, including thought chain analysis, error type diagnosis, and reasoning depth evaluation. Experimental results show that QwQ-32B-Preview achieves the best score of 20.93 followed by DeepSeek-V3 with a score of 16.38, suggesting that models trained with specialized reasoning tasks significantly outperform general-purpose models (even larger than reasoning-oriented models) in programming. Further analysis also reveals key areas for programming capability enhancement, e.g., algorithm adaptability and reasoning sufficiency, providing important insights for the future development of reasoning models.

Tool learning has emerged as a promising direction by extending Large Language Models' (LLMs) capabilities with external tools. Existing tool learning studies primarily focus on the general-purpose tool-use capability, which addresses explicit user requirements in instructions. However, they overlook the importance of personalized tool-use capability, leading to an inability to handle implicit user preferences. To address the limitation, we first formulate the task of personalized tool learning, which integrates user's interaction history towards personalized tool usage. To fill the gap of missing benchmarks, we construct PEToolBench, featuring diverse user preferences reflected in interaction history under three distinct personalized settings, and encompassing a wide range of tool-use scenarios. Moreover, we propose a framework PEToolLLaMA to adapt LLMs to the personalized tool learning task, which is trained through supervised fine-tuning and direct preference optimization. Extensive experiments on PEToolBench demonstrate the superiority of PEToolLLaMA over existing LLMs.

Visual-language models (VLM) have emerged as a powerful tool for learning a unified embedding space for vision and language. Inspired by large language models, which have demonstrated strong reasoning and multi-task capabilities, visual large language models (VLLMs) are gaining increasing attention for building general-purpose VLMs. Despite the significant progress made in VLLMs, the related literature remains limited, particularly from a comprehensive application perspective, encompassing generalized and specialized applications across vision (image, video, depth), action, and language modalities. In this survey, we focus on the diverse applications of VLLMs, examining their using scenarios, identifying ethics consideration and challenges, and discussing future directions for their development. By synthesizing these contents, we aim to provide a comprehensive guide that will pave the way for future innovations and broader applications of VLLMs. The paper list repository is available: https://github.com/JackYFL/awesome-VLLMs.

Large language models (LLMs) have made significant progress in machine translation (MT). However, their potential in domain-specific MT remains under-explored. Current LLM-based MT systems still face several challenges. First, for LLMs with in-context learning, their effectiveness is highly sensitive to input translation examples, and processing them can increase inference costs. They often require extra post-processing due to over-generation. Second, LLMs with fine-tuning on domain-specific data often require high training costs for domain adaptation, and may weaken the zero-shot MT capabilities of LLMs due to over-specialization. The aforementioned methods can struggle to translate rare words in domain transfer scenarios. To address these challenges, this paper proposes a prompt-oriented fine-tuning method, denoted as LlamaIT, to effectively and efficiently fine-tune a general-purpose LLM for domain-specific MT tasks. First, we construct a task-specific mix-domain dataset, which is then used to fine-tune the LLM with LoRA. This can eliminate the need for input translation examples, post-processing, or over-specialization. By zero-shot prompting with instructions, we adapt the MT tasks to the target domain at inference time. To further elicit the MT capability for rare words, we construct new prompts by incorporating domain-specific bilingual vocabulary. We also conduct extensive experiments on both publicly available and self-constructed datasets. The results show that our LlamaIT can significantly enhance the domain-specific MT capabilities of the LLM, meanwhile preserving its zero-shot MT capabilities.

With tremendous efforts on developing effective e-commerce models, conventional e-commerce models show limited success in generalist e-commerce modeling, and suffer from unsatisfactory performance on new users and new products - a typical out-of-domain generalization challenge. Meanwhile, large language models (LLMs) demonstrate outstanding performance in generalist modeling and out-of-domain generalizability in many fields. Toward fully unleashing their power for e-commerce, in this paper, we construct ECInstruct, the first open-sourced, large-scale, and high-quality benchmark instruction dataset for e-commerce. Leveraging ECInstruct, we develop eCeLLM, a series of e-commerce LLMs, by instruction-tuning general-purpose LLMs. Our comprehensive experiments and evaluation demonstrate that eCeLLM models substantially outperform baseline models, including the most advanced GPT-4, and the state-of-the-art task-specific models in in-domain evaluation. Moreover, eCeLLM exhibits excellent generalizability to out-of-domain settings, including unseen products and unseen instructions, highlighting its superiority as a generalist e-commerce model. Both the ECInstruct dataset and the eCeLLM models show great potential in empowering versatile and effective LLMs for e-commerce. ECInstruct and eCeLLM models are publicly accessible through https://ninglab.github.io/eCeLLM.

With the rapid development of artificial intelligence, large language models (LLMs) have shown promising capabilities in mimicking human-level language comprehension and reasoning. This has sparked significant interest in applying LLMs to enhance various aspects of healthcare, ranging from medical education to clinical decision support. However, medicine involves multifaceted data modalities and nuanced reasoning skills, presenting challenges for integrating LLMs. This paper provides a comprehensive review on the applications and implications of LLMs in medicine. It begins by examining the fundamental applications of general-purpose and specialized LLMs, demonstrating their utilities in knowledge retrieval, research support, clinical workflow automation, and diagnostic assistance. Recognizing the inherent multimodality of medicine, the review then focuses on multimodal LLMs, investigating their ability to process diverse data types like medical imaging and EHRs to augment diagnostic accuracy. To address LLMs' limitations regarding personalization and complex clinical reasoning, the paper explores the emerging development of LLM-powered autonomous agents for healthcare. Furthermore, it summarizes the evaluation methodologies for assessing LLMs' reliability and safety in medical contexts. Overall, this review offers an extensive analysis on the transformative potential of LLMs in modern medicine. It also highlights the pivotal need for continuous optimizations and ethical oversight before these models can be effectively integrated into clinical practice. Visit https://github.com/mingze-yuan/Awesome-LLM-Healthcare for an accompanying GitHub repository containing latest papers.

Spurred by advancements in scale, large language models (LLMs) have demonstrated the ability to perform a variety of natural language processing (NLP) tasks zero-shot -- i.e., without adaptation on downstream data. Recently, the debut of ChatGPT has drawn a great deal of attention from the natural language processing (NLP) community due to the fact that it can generate high-quality responses to human input and self-correct previous mistakes based on subsequent conversations. However, it is not yet known whether ChatGPT can serve as a generalist model that can perform many NLP tasks zero-shot. In this work, we empirically analyze the zero-shot learning ability of ChatGPT by evaluating it on 20 popular NLP datasets covering 7 representative task categories. With extensive empirical studies, we demonstrate both the effectiveness and limitations of the current version of ChatGPT. We find that ChatGPT performs well on many tasks favoring reasoning capabilities (e.g., arithmetic reasoning) while it still faces challenges when solving specific tasks such as sequence tagging. We additionally provide in-depth analysis through qualitative case studies.

This paper explores the limits of the current generation of large language models for program synthesis in general purpose programming languages. We evaluate a collection of such models (with between 244M and 137B parameters) on two new benchmarks, MBPP and MathQA-Python, in both the few-shot and fine-tuning regimes. Our benchmarks are designed to measure the ability of these models to synthesize short Python programs from natural language descriptions. The Mostly Basic Programming Problems (MBPP) dataset contains 974 programming tasks, designed to be solvable by entry-level programmers. The MathQA-Python dataset, a Python version of the MathQA benchmark, contains 23914 problems that evaluate the ability of the models to synthesize code from more complex text. On both datasets, we find that synthesis performance scales log-linearly with model size. Our largest models, even without finetuning on a code dataset, can synthesize solutions to 59.6 percent of the problems from MBPP using few-shot learning with a well-designed prompt. Fine-tuning on a held-out portion of the dataset improves performance by about 10 percentage points across most model sizes. On the MathQA-Python dataset, the largest fine-tuned model achieves 83.8 percent accuracy. Going further, we study the model's ability to engage in dialog about code, incorporating human feedback to improve its solutions. We find that natural language feedback from a human halves the error rate compared to the model's initial prediction. Additionally, we conduct an error analysis to shed light on where these models fall short and what types of programs are most difficult to generate. Finally, we explore the semantic grounding of these models by fine-tuning them to predict the results of program execution. We find that even our best models are generally unable to predict the output of a program given a specific input.

We report the presence of a simple neural mechanism that represents an input-output function as a vector within autoregressive transformer language models (LMs). Using causal mediation analysis on a diverse range of in-context-learning (ICL) tasks, we find that a small number attention heads transport a compact representation of the demonstrated task, which we call a function vector (FV). FVs are robust to changes in context, i.e., they trigger execution of the task on inputs such as zero-shot and natural text settings that do not resemble the ICL contexts from which they are collected. We test FVs across a range of tasks, models, and layers and find strong causal effects across settings in middle layers. We investigate the internal structure of FVs and find while that they often contain information that encodes the output space of the function, this information alone is not sufficient to reconstruct an FV. Finally, we test semantic vector composition in FVs, and find that to some extent they can be summed to create vectors that trigger new complex tasks. Taken together, our findings suggest that LLMs contain internal abstractions of general-purpose functions that can be invoked in a variety of contexts.

We present Autoregressive Representation Alignment (ARRA), a new training framework that unlocks global-coherent text-to-image generation in autoregressive LLMs without architectural changes. Unlike prior work that requires complex architectural redesigns, ARRA aligns LLM hidden states with visual representations from external visual foundational models via a global visual alignment loss and a hybrid token, <HYBNEXT>. This token enforces dual constraints: local next-token prediction and global semantic distillation, enabling LLMs to implicitly learn spatial and contextual coherence while retaining their original autoregressive paradigm. Extensive experiments validate ARRA's plug-and-play versatility. When training from text-generation-only LLMs or random initialization, ARRA reduces FID by 25.5% (MIMIC-CXR), 8.8% (DeepEyeNet), and 7.5% (ImageNet) for advanced autoregressive LLMs like Chameleon and LlamaGen, all without framework modifications. For domain adaption, ARRA aligns general-purpose LLMs with specialized models (e.g., BioMedCLIP), achieving an 18.6% FID reduction over direct fine-tuning on medical imaging (MIMIC-CXR). By demonstrating that training objective redesign -- not just architectural innovation -- can resolve cross-modal global coherence challenges, ARRA offers a complementary paradigm for advancing autoregressive models. Code and models will be released to advance autoregressive image generation.

Large language models (LLMs) such as ChatGPT have received immense interest for their general-purpose language understanding and, in particular, their ability to generate high-quality text or computer code. For many professions, LLMs represent an invaluable tool that can speed up and improve the quality of work. In this note, we discuss to what extent they can aid professional mathematicians. We first provide a mathematical description of the transformer model used in all modern language models. Based on recent studies, we then outline best practices and potential issues and report on the mathematical abilities of language models. Finally, we shed light on the potential of LMMs to change how mathematicians work.

Hallucinations in multimodal large language models (MLLMs) -- where the model generates content inconsistent with the input image -- pose significant risks in real-world applications, from misinformation in visual question answering to unsafe errors in decision-making. Existing benchmarks primarily test recognition accuracy, i.e., evaluating whether models can select the correct answer among distractors. This overlooks an equally critical capability for trustworthy AI: recognizing when none of the provided options are correct, a behavior reflecting epistemic humility. We present HumbleBench, a new hallucination benchmark designed to evaluate MLLMs' ability to reject plausible but incorrect answers across three hallucination types: object, relation, and attribute. Built from a panoptic scene graph dataset, we leverage fine-grained scene graph annotations to extract ground-truth entities and relations, and prompt GPT-4-Turbo to generate multiple-choice questions, followed by a rigorous manual filtering process. Each question includes a "None of the above" option, requiring models not only to recognize correct visual information but also to identify when no provided answer is valid. We evaluate a variety of state-of-the-art MLLMs -- including both general-purpose and specialized reasoning models -- on HumbleBench and share valuable findings and insights with the community. By incorporating explicit false-option rejection, HumbleBench fills a key gap in current evaluation suites, providing a more realistic measure of MLLM reliability in safety-critical settings. Our code and dataset are released publicly and can be accessed at https://github.com/maifoundations/HumbleBench.

Intellectual Property (IP) is a unique domain that integrates technical and legal knowledge, making it inherently complex and knowledge-intensive. As large language models (LLMs) continue to advance, they show great potential for processing IP tasks, enabling more efficient analysis, understanding, and generation of IP-related content. However, existing datasets and benchmarks either focus narrowly on patents or cover limited aspects of the IP field, lacking alignment with real-world scenarios. To bridge this gap, we introduce the first comprehensive IP task taxonomy and a large, diverse bilingual benchmark, IPBench, covering 8 IP mechanisms and 20 tasks. This benchmark is designed to evaluate LLMs in real-world intellectual property applications, encompassing both understanding and generation. We benchmark 16 LLMs, ranging from general-purpose to domain-specific models, and find that even the best-performing model achieves only 75.8% accuracy, revealing substantial room for improvement. Notably, open-source IP and law-oriented models lag behind closed-source general-purpose models. We publicly release all data and code of IPBench and will continue to update it with additional IP-related tasks to better reflect real-world challenges in the intellectual property domain.

We propose Rec-R1, a general reinforcement learning framework that bridges large language models (LLMs) with recommendation systems through closed-loop optimization. Unlike prompting and supervised fine-tuning (SFT), Rec-R1 directly optimizes LLM generation using feedback from a fixed black-box recommendation model, without relying on synthetic SFT data from proprietary models such as GPT-4o. This avoids the substantial cost and effort required for data distillation. To verify the effectiveness of Rec-R1, we evaluate it on two representative tasks: product search and sequential recommendation. Experimental results demonstrate that Rec-R1 not only consistently outperforms prompting- and SFT-based methods, but also achieves significant gains over strong discriminative baselines, even when used with simple retrievers such as BM25. Moreover, Rec-R1 preserves the general-purpose capabilities of the LLM, unlike SFT, which often impairs instruction-following and reasoning. These findings suggest Rec-R1 as a promising foundation for continual task-specific adaptation without catastrophic forgetting.

Sentiment analysis is a widely researched area within Natural Language Processing (NLP), attracting significant interest due to the advent of automated solutions. Despite this, the task remains challenging because of the inherent complexity of languages and the subjective nature of sentiments. It is even more challenging for less-studied and less-resourced languages such as Lithuanian. Our review of existing Lithuanian NLP research reveals that traditional machine learning methods and classification algorithms have limited effectiveness for the task. In this work, we address sentiment analysis of Lithuanian five-star-based online reviews from multiple domains that we collect and clean. We apply transformer models to this task for the first time, exploring the capabilities of pre-trained multilingual Large Language Models (LLMs), specifically focusing on fine-tuning BERT and T5 models. Given the inherent difficulty of the task, the fine-tuned models perform quite well, especially when the sentiments themselves are less ambiguous: 80.74% and 89.61% testing recognition accuracy of the most popular one- and five-star reviews respectively. They significantly outperform current commercial state-of-the-art general-purpose LLM GPT-4. We openly share our fine-tuned LLMs online.

Transformers, the backbone of modern large language models (LLMs), face inherent architectural limitations that impede their reasoning capabilities. Unlike recurrent networks, Transformers lack recurrent connections, confining them to constant-depth computation. This restriction places them in the complexity class TC^0, making them theoretically incapable of solving tasks that demand increasingly deep reasoning as input length grows. Counting, a fundamental component of many reasoning tasks, also requires reasoning depth to grow linearly to be performed inductively. While previous studies have established the upper limits of counting ability in Transformer-based expert models (i.e., models specifically trained for counting tasks), these findings do not directly extend to general-purpose LLMs due to differences in reasoning mechanisms. Recent work has highlighted how Chain of Thought (CoT) reasoning can help alleviate some of the architectural limitations of Transformers in counting tasks. However, little attention has been paid to the role of tokenization in these models. Unlike expert models that often use character-level tokenization, LLMs typically rely on byte-level (BPE) tokenizers, which fundamentally alters the way reasoning is processed. Our work investigates the impact of tokenization on the counting abilities of LLMs, uncovering substantial performance variations based on input tokenization differences. We provide both theoretical and experimental analyses, offering insights into how tokenization choices can undermine models' theoretical computability, thereby inspiring the design of new tokenization methods to enhance reasoning in LLMs.

The Automated Audio Captioning (AAC) task asks models to generate natural language descriptions of an audio input. Evaluating these machine-generated audio captions is a complex task that requires considering diverse factors, among them, auditory scene understanding, sound-object inference, temporal coherence, and the environmental context of the scene. While current methods focus on specific aspects, they often fail to provide an overall score that aligns well with human judgment. In this work, we propose CLAIR-A, a simple and flexible method that leverages the zero-shot capabilities of large language models (LLMs) to evaluate candidate audio captions by directly asking LLMs for a semantic distance score. In our evaluations, CLAIR-A better predicts human judgements of quality compared to traditional metrics, with a 5.8% relative accuracy improvement compared to the domain-specific FENSE metric and up to 11% over the best general-purpose measure on the Clotho-Eval dataset. Moreover, CLAIR-A offers more transparency by allowing the language model to explain the reasoning behind its scores, with these explanations rated up to 30% better by human evaluators than those provided by baseline methods. CLAIR-A is made publicly available at https://github.com/DavidMChan/clair-a.

Retrieval-augmented generation (RAG) enhances the question-answering (QA) abilities of large language models (LLMs) by integrating external knowledge. However, adapting general-purpose RAG systems to specialized fields such as science and medicine poses unique challenges due to distribution shifts and limited access to domain-specific data. To tackle this, we propose SimRAG, a self-training approach that equips the LLM with joint capabilities of question answering and question generation for domain adaptation. Our method first fine-tunes the LLM on instruction-following, question-answering, and search-related data. Then, it prompts the same LLM to generate diverse domain-relevant questions from unlabeled corpora, with an additional filtering strategy to retain high-quality synthetic examples. By leveraging these synthetic examples, the LLM can improve their performance on domain-specific RAG tasks. Experiments on 11 datasets, spanning two backbone sizes and three domains, demonstrate that SimRAG outperforms baselines by 1.2\%--8.6\%.

We show that autoregressive decoding of a transformer-based language model can realize universal computation, without external intervention or modification of the model's weights. Establishing this result requires understanding how a language model can process arbitrarily long inputs using a bounded context. For this purpose, we consider a generalization of autoregressive decoding where, given a long input, emitted tokens are appended to the end of the sequence as the context window advances. We first show that the resulting system corresponds to a classical model of computation, a Lag system, that has long been known to be computationally universal. By leveraging a new proof, we show that a universal Turing machine can be simulated by a Lag system with 2027 production rules. We then investigate whether an existing large language model can simulate the behaviour of such a universal Lag system. We give an affirmative answer by showing that a single system-prompt can be developed for gemini-1.5-pro-001 that drives the model, under deterministic (greedy) decoding, to correctly apply each of the 2027 production rules. We conclude that, by the Church-Turing thesis, prompted gemini-1.5-pro-001 with extended autoregressive (greedy) decoding is a general purpose computer.

With the emergence of Large Language Models (LLMs), there has been a significant improvement in the programming capabilities of models, attracting growing attention from researchers. We propose CodeApex, a bilingual benchmark dataset focusing on the programming comprehension and code generation abilities of LLMs. CodeApex comprises three types of multiple-choice questions: conceptual understanding, commonsense reasoning, and multi-hop reasoning, designed to evaluate LLMs on programming comprehension tasks. Additionally, CodeApex utilizes algorithmic questions and corresponding test cases to assess the code quality generated by LLMs. We evaluate 14 state-of-the-art LLMs, including both general-purpose and specialized models. GPT exhibits the best programming capabilities, achieving approximate accuracies of 50% and 56% on the two tasks, respectively. There is still significant room for improvement in programming tasks. We hope that CodeApex can serve as a reference for evaluating the coding capabilities of LLMs, further promoting their development and growth. Datasets are released at https://github.com/APEXLAB/CodeApex.git. CodeApex submission website is https://apex.sjtu.edu.cn/codeapex/.

By conditioning on natural language instructions, large language models (LLMs) have displayed impressive capabilities as general-purpose computers. However, task performance depends significantly on the quality of the prompt used to steer the model, and most effective prompts have been handcrafted by humans. Inspired by classical program synthesis and the human approach to prompt engineering, we propose Automatic Prompt Engineer (APE) for automatic instruction generation and selection. In our method, we treat the instruction as the "program," optimized by searching over a pool of instruction candidates proposed by an LLM in order to maximize a chosen score function. To evaluate the quality of the selected instruction, we evaluate the zero-shot performance of another LLM following the selected instruction. Experiments on 24 NLP tasks show that our automatically generated instructions outperform the prior LLM baseline by a large margin and achieve better or comparable performance to the instructions generated by human annotators on 19/24 tasks. We conduct extensive qualitative and quantitative analyses to explore the performance of APE. We show that APE-engineered prompts can be applied to steer models toward truthfulness and/or informativeness, as well as to improve few-shot learning performance by simply prepending them to standard in-context learning prompts. Please check out our webpage at https://sites.google.com/view/automatic-prompt-engineer.

Large Language Models (LLMs) have transformed both everyday life and scientific research. However, adapting LLMs from general-purpose models to specialized tasks remains challenging, particularly in resource-constrained environments. Low-Rank Adaptation (LoRA), a prominent method within Parameter-Efficient Fine-Tuning (PEFT), has emerged as a promising approach to LLMs by approximating model weight updates using low-rank decomposition. However, LoRA is limited by its uniform rank ( r ) allocation to each incremental matrix, and existing rank allocation techniques aimed at addressing this issue remain computationally inefficient, complex, and unstable, hindering practical applications. To address these limitations, we propose Sensitivity-LoRA, an efficient fine-tuning method that dynamically allocates ranks to weight matrices based on both their global and local sensitivities. It leverages the second-order derivatives (Hessian Matrix) of the loss function to effectively capture weight sensitivity, enabling optimal rank allocation with minimal computational overhead. Our experimental results have demonstrated robust effectiveness, efficiency and stability of Sensitivity-LoRA across diverse tasks and benchmarks.

Large language models (LLMs) have revolutionised many fields, with LLM-as-a-service (LLMSaaS) offering accessible, general-purpose solutions without costly task-specific training. In contrast to the widely studied prompt engineering for directly solving tasks (in vivo), this paper explores LLMs' potential for in-vitro applications: using LLM-generated labels to improve supervised training of mainstream models. We examine two strategies - (1) noisy label correction and (2) training data augmentation - in empathy computing, an emerging task to predict psychology-based questionnaire outcomes from inputs like textual narratives. Crowdsourced datasets in this domain often suffer from noisy labels that misrepresent underlying empathy. We show that replacing or supplementing these crowdsourced labels with LLM-generated labels, developed using psychology-based scale-aware prompts, achieves statistically significant accuracy improvements. Notably, the RoBERTa pre-trained language model (PLM) trained with noise-reduced labels yields a state-of-the-art Pearson correlation coefficient of 0.648 on the public NewsEmp benchmarks. This paper further analyses evaluation metric selection and demographic biases to help guide the future development of more equitable empathy computing models. Code and LLM-generated labels are available at https://github.com/hasan-rakibul/LLMPathy.

Generating lifelike human motions from descriptive texts has experienced remarkable research focus in the recent years, propelled by the emerging requirements of digital humans.Despite impressive advances, existing approaches are often constrained by limited control modalities, task specificity, and focus solely on body motion representations.In this paper, we present MotionGPT-2, a unified Large Motion-Language Model (LMLM) that addresses these limitations. MotionGPT-2 accommodates multiple motion-relevant tasks and supporting multimodal control conditions through pre-trained Large Language Models (LLMs). It quantizes multimodal inputs-such as text and single-frame poses-into discrete, LLM-interpretable tokens, seamlessly integrating them into the LLM's vocabulary. These tokens are then organized into unified prompts, guiding the LLM to generate motion outputs through a pretraining-then-finetuning paradigm. We also show that the proposed MotionGPT-2 is highly adaptable to the challenging 3D holistic motion generation task, enabled by the innovative motion discretization framework, Part-Aware VQVAE, which ensures fine-grained representations of body and hand movements. Extensive experiments and visualizations validate the effectiveness of our method, demonstrating the adaptability of MotionGPT-2 across motion generation, motion captioning, and generalized motion completion tasks.

Current Large Language Models (LLMs) are predominantly designed with English as the primary language, and even the few that are multilingual tend to exhibit strong English-centric biases. Much like speakers who might produce awkward expressions when learning a second language, LLMs often generate unnatural outputs in non-English languages, reflecting English-centric patterns in both vocabulary and grammar. Despite the importance of this issue, the naturalness of multilingual LLM outputs has received limited attention. In this paper, we address this gap by introducing novel automatic corpus-level metrics to assess the lexical and syntactic naturalness of LLM outputs in a multilingual context. Using our new metrics, we evaluate state-of-the-art LLMs on a curated benchmark in French and Chinese, revealing a tendency towards English-influenced patterns. To mitigate this issue, we also propose a simple and effective alignment method to improve the naturalness of an LLM in a target language and domain, achieving consistent improvements in naturalness without compromising the performance on general-purpose benchmarks. Our work highlights the importance of developing multilingual metrics, resources and methods for the new wave of multilingual LLMs.

Large Language Models (LLMs) demonstrate remarkable capabilities in replicating human tasks and boosting productivity. However, their direct application for data extraction presents limitations due to a prioritisation of fluency over factual accuracy and a restricted ability to manipulate specific information. Therefore to overcome these limitations, this research leverages the knowledge representation power of pre-trained LLMs and the targeted information access enabled by RAG models, this research investigates a general-purpose accurate data scraping recipe for RAG models designed for language generation. To capture knowledge in a more modular and interpretable way, we use pre trained language models with a latent knowledge retriever, which allows the model to retrieve and attend over documents from a large corpus. We utilised RAG model architecture and did an in-depth analysis of their capabilities under three tasks: (i) Semantic Classification of HTML elements, (ii) Chunking HTML text for effective understanding, and (iii) comparing results from different LLMs and ranking algorithms. While previous work has developed dedicated architectures and training procedures for HTML understanding and extraction, we show that LLMs pre-trained on standard natural language with an addition of effective chunking, searching and ranking algorithms, can prove to be efficient data scraping tool to extract complex data from unstructured text. Future research directions include addressing the challenges of provenance tracking and dynamic knowledge updates within the proposed RAG-based data extraction framework. By overcoming these limitations, this approach holds the potential to revolutionise data extraction from vast repositories of textual information.

The current generation of large language models (LLMs) is typically designed for broad, general-purpose applications, while domain-specific LLMs, especially in vertical fields like medicine, remain relatively scarce. In particular, the development of highly efficient and practical LLMs for the medical domain is challenging due to the complexity of medical knowledge and the limited availability of high-quality data. To bridge this gap, we introduce Baichuan-M1, a series of large language models specifically optimized for medical applications. Unlike traditional approaches that simply continue pretraining on existing models or apply post-training to a general base model, Baichuan-M1 is trained from scratch with a dedicated focus on enhancing medical capabilities. Our model is trained on 20 trillion tokens and incorporates a range of effective training methods that strike a balance between general capabilities and medical expertise. As a result, Baichuan-M1 not only performs strongly across general domains such as mathematics and coding but also excels in specialized medical fields. We have open-sourced Baichuan-M1-14B, a mini version of our model, which can be accessed through the following links.

Building on the success of text-based reasoning models like DeepSeek-R1, extending these capabilities to multimodal reasoning holds great promise. While recent works have attempted to adapt DeepSeek-R1-style reinforcement learning (RL) training paradigms to multimodal large language models (MLLM), focusing on domain-specific tasks like math and visual perception, a critical question remains: How can we achieve the general-purpose visual-language reasoning through RL? To address this challenge, we make three key efforts: (1) A novel Scalable Multimodal QA Synthesis pipeline that autonomously generates context-aware, reasoning-centric question-answer (QA) pairs directly from the given images. (2) The open-source WeThink dataset containing over 120K multimodal QA pairs with annotated reasoning paths, curated from 18 diverse dataset sources and covering various question domains. (3) A comprehensive exploration of RL on our dataset, incorporating a hybrid reward mechanism that combines rule-based verification with model-based assessment to optimize RL training efficiency across various task domains. Across 14 diverse MLLM benchmarks, we demonstrate that our WeThink dataset significantly enhances performance, from mathematical reasoning to diverse general multimodal tasks. Moreover, we show that our automated data pipeline can continuously increase data diversity to further improve model performance.

As Large Language Models (LLMs) become more pervasive across various users and scenarios, identifying potential issues when using these models becomes essential. Examples of such issues include: bias, inconsistencies, and hallucination. Although auditing the LLM for these problems is often warranted, such a process is neither easy nor accessible for most. An effective method is to probe the LLM using different versions of the same question. This could expose inconsistencies in its knowledge or operation, indicating potential for bias or hallucination. However, to operationalize this auditing method at scale, we need an approach to create those probes reliably and automatically. In this paper we propose the LLMAuditor framework which is an automatic, and scalable solution, where one uses a different LLM along with human-in-the-loop (HIL). This approach offers verifiability and transparency, while avoiding circular reliance on the same LLM, and increasing scientific rigor and generalizability. Specifically, LLMAuditor includes two phases of verification using humans: standardized evaluation criteria to verify responses, and a structured prompt template to generate desired probes. A case study using questions from the TruthfulQA dataset demonstrates that we can generate a reliable set of probes from one LLM that can be used to audit inconsistencies in a different LLM. This process is enhanced by our structured prompt template with HIL, which not only boosts the reliability of our approach in auditing but also yields the delivery of less hallucinated results. The novelty of our research stems from the development of a comprehensive, general-purpose framework that includes a HIL verified prompt template for auditing responses generated by LLMs.

Business Process Management (BPM) aims to improve organizational activities and their outcomes by managing the underlying processes. To achieve this, it is often necessary to consider information from various sources, including unstructured textual documents. Therefore, researchers have developed several BPM-specific solutions that extract information from textual documents using Natural Language Processing techniques. These solutions are specific to their respective tasks and cannot accomplish multiple process-related problems as a general-purpose instrument. However, in light of the recent emergence of Large Language Models (LLMs) with remarkable reasoning capabilities, such a general-purpose instrument with multiple applications now appears attainable. In this paper, we illustrate how LLMs can accomplish text-related BPM tasks by applying a specific LLM to three exemplary tasks: mining imperative process models from textual descriptions, mining declarative process models from textual descriptions, and assessing the suitability of process tasks from textual descriptions for robotic process automation. We show that, without extensive configuration or prompt engineering, LLMs perform comparably to or better than existing solutions and discuss implications for future BPM research as well as practical usage.

Large language models (LLMs) are widely applied in chatbots, code generators, and search engines. Workloads such as chain-of-thought, complex reasoning, and agent services significantly increase the inference cost by invoking the model repeatedly. Optimization methods such as parallelism, compression, and caching have been adopted to reduce costs, but the diverse service requirements make it hard to select the right method. Recently, specialized LLM inference engines have emerged as a key component for integrating the optimization methods into service-oriented infrastructures. However, a systematic study on inference engines is still lacking. This paper provides a comprehensive evaluation of 25 open-source and commercial inference engines. We examine each inference engine in terms of ease-of-use, ease-of-deployment, general-purpose support, scalability, and suitability for throughput- and latency-aware computation. Furthermore, we explore the design goals of each inference engine by investigating the optimization techniques it supports. In addition, we assess the ecosystem maturity of open source inference engines and handle the performance and cost policy of commercial solutions. We outline future research directions that include support for complex LLM-based services, support of various hardware, and enhanced security, offering practical guidance to researchers and developers in selecting and designing optimized LLM inference engines. We also provide a public repository to continually track developments in this fast-evolving field: https://github.com/sihyeong/Awesome-LLM-Inference-Engine

We demonstrate that Contrastive Decoding -- a simple, computationally light, and training-free text generation method proposed by Li et al 2022 -- achieves large out-of-the-box improvements over greedy decoding on a variety of reasoning tasks. Originally shown to improve the perceived quality of long-form text generation, Contrastive Decoding searches for strings that maximize a weighted difference in likelihood between strong and weak models. We show that Contrastive Decoding leads LLaMA-65B to outperform LLaMA 2, GPT-3.5 and PaLM 2-L on the HellaSwag commonsense reasoning benchmark, and to outperform LLaMA 2, GPT-3.5 and PaLM-540B on the GSM8K math word reasoning benchmark, in addition to improvements on a collection of other tasks. Analysis suggests that Contrastive Decoding improves over existing methods by preventing some abstract reasoning errors, as well as by avoiding simpler modes such as copying sections of the input during chain-of-thought. Overall, Contrastive Decoding outperforms nucleus sampling for long-form generation and greedy decoding for reasoning tasks, making it a powerful general purpose method for generating text from language models.

We investigate the potential implications of large language models (LLMs), such as Generative Pre-trained Transformers (GPTs), on the U.S. labor market, focusing on the increased capabilities arising from LLM-powered software compared to LLMs on their own. Using a new rubric, we assess occupations based on their alignment with LLM capabilities, integrating both human expertise and GPT-4 classifications. Our findings reveal that around 80% of the U.S. workforce could have at least 10% of their work tasks affected by the introduction of LLMs, while approximately 19% of workers may see at least 50% of their tasks impacted. We do not make predictions about the development or adoption timeline of such LLMs. The projected effects span all wage levels, with higher-income jobs potentially facing greater exposure to LLM capabilities and LLM-powered software. Significantly, these impacts are not restricted to industries with higher recent productivity growth. Our analysis suggests that, with access to an LLM, about 15% of all worker tasks in the US could be completed significantly faster at the same level of quality. When incorporating software and tooling built on top of LLMs, this share increases to between 47 and 56% of all tasks. This finding implies that LLM-powered software will have a substantial effect on scaling the economic impacts of the underlying models. We conclude that LLMs such as GPTs exhibit traits of general-purpose technologies, indicating that they could have considerable economic, social, and policy implications.

This paper explores the intersection of psychology and artificial intelligence through the development and evaluation of specialized Large Language Models (LLMs). We introduce PsychoLex, a suite of resources designed to enhance LLMs' proficiency in psychological tasks in both Persian and English. Key contributions include the PsychoLexQA dataset for instructional content and the PsychoLexEval dataset for rigorous evaluation of LLMs in complex psychological scenarios. Additionally, we present the PsychoLexLLaMA model, optimized specifically for psychological applications, demonstrating superior performance compared to general-purpose models. The findings underscore the potential of tailored LLMs for advancing psychological research and applications, while also highlighting areas for further refinement. This research offers a foundational step towards integrating LLMs into specialized psychological domains, with implications for future advancements in AI-driven psychological practice.

During Automated Program Repair (APR), it can be challenging to synthesize correct patches for real-world systems in general-purpose programming languages. Recent Large Language Models (LLMs) have been shown to be helpful "copilots" in assisting developers with various coding tasks, and have also been directly applied for patch synthesis. However, most LLMs treat programs as sequences of tokens, meaning that they are ignorant of the underlying semantics constraints of the target programming language. This results in plenty of statically invalid generated patches, impeding the practicality of the technique. Therefore, we propose Repilot, a framework to further copilot the AI "copilots" (i.e., LLMs) by synthesizing more valid patches during the repair process. Our key insight is that many LLMs produce outputs autoregressively (i.e., token by token), resembling human writing programs, which can be significantly boosted and guided through a Completion Engine. Repilot synergistically synthesizes a candidate patch through the interaction between an LLM and a Completion Engine, which 1) prunes away infeasible tokens suggested by the LLM and 2) proactively completes the token based on the suggestions provided by the Completion Engine. Our evaluation on a subset of the widely-used Defects4j 1.2 and 2.0 datasets shows that Repilot fixes 66 and 50 bugs, respectively, surpassing the best-performing baseline by 14 and 16 bugs fixed. More importantly, Repilot is capable of producing more valid and correct patches than the base LLM when given the same generation budget.

Endoscopic procedures are essential for diagnosing and treating internal diseases, and multi-modal large language models (MLLMs) are increasingly applied to assist in endoscopy analysis. However, current benchmarks are limited, as they typically cover specific endoscopic scenarios and a small set of clinical tasks, failing to capture the real-world diversity of endoscopic scenarios and the full range of skills needed in clinical workflows. To address these issues, we introduce EndoBench, the first comprehensive benchmark specifically designed to assess MLLMs across the full spectrum of endoscopic practice with multi-dimensional capacities. EndoBench encompasses 4 distinct endoscopic scenarios, 12 specialized clinical tasks with 12 secondary subtasks, and 5 levels of visual prompting granularities, resulting in 6,832 rigorously validated VQA pairs from 21 diverse datasets. Our multi-dimensional evaluation framework mirrors the clinical workflow--spanning anatomical recognition, lesion analysis, spatial localization, and surgical operations--to holistically gauge the perceptual and diagnostic abilities of MLLMs in realistic scenarios. We benchmark 23 state-of-the-art models, including general-purpose, medical-specialized, and proprietary MLLMs, and establish human clinician performance as a reference standard. Our extensive experiments reveal: (1) proprietary MLLMs outperform open-source and medical-specialized models overall, but still trail human experts; (2) medical-domain supervised fine-tuning substantially boosts task-specific accuracy; and (3) model performance remains sensitive to prompt format and clinical task complexity. EndoBench establishes a new standard for evaluating and advancing MLLMs in endoscopy, highlighting both progress and persistent gaps between current models and expert clinical reasoning. We publicly release our benchmark and code.

When using large language models (LLMs) in high-stakes applications, we need to know when we can trust their predictions. Some works argue that prompting high-performance LLMs is sufficient to produce calibrated uncertainties, while others introduce sampling methods that can be prohibitively expensive. In this work, we first argue that prompting on its own is insufficient to achieve good calibration and then show that fine-tuning on a small dataset of correct and incorrect answers can create an uncertainty estimate with good generalization and small computational overhead. We show that a thousand graded examples are sufficient to outperform baseline methods and that training through the features of a model is necessary for good performance and tractable for large open-source models when using LoRA. We also investigate the mechanisms that enable reliable LLM uncertainty estimation, finding that many models can be used as general-purpose uncertainty estimators, applicable not just to their own uncertainties but also the uncertainty of other models. Lastly, we show that uncertainty estimates inform human use of LLMs in human-AI collaborative settings through a user study.

With the proliferation of open-sourced Large Language Models (LLMs) and efficient finetuning techniques, we are on the cusp of the emergence of numerous domain-specific LLMs that have been finetuned for expertise across specialized fields and applications for which the current general-purpose LLMs are unsuitable. In academia, this technology has the potential to revolutionize the way we conduct systematic literature reviews (SLRs), access knowledge and generate new insights. This paper proposes an AI-enabled methodological framework that combines the power of LLMs with the rigorous reporting guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). By finetuning LLMs on domain-specific academic papers that have been selected as a result of a rigorous SLR process, the proposed PRISMA-DFLLM (for Domain-specific Finetuned LLMs) reporting guidelines offer the potential to achieve greater efficiency, reusability and scalability, while also opening the potential for conducting incremental living systematic reviews with the aid of LLMs. Additionally, the proposed approach for leveraging LLMs for SLRs enables the dissemination of finetuned models, empowering researchers to accelerate advancements and democratize cutting-edge research. This paper presents the case for the feasibility of finetuned LLMs to support rigorous SLRs and the technical requirements for realizing this. This work then proposes the extended PRISMA-DFLLM checklist of reporting guidelines as well as the advantages, challenges, and potential implications of implementing PRISMA-DFLLM. Finally, a future research roadmap to develop this line of AI-enabled SLRs is presented, paving the way for a new era of evidence synthesis and knowledge discovery.

Large Language Models (LLMs) pre-trained on internet-scale datasets have shown impressive capabilities in code understanding, synthesis, and general purpose question-and-answering. Key to their performance is the substantial prior knowledge acquired during training and their ability to reason over extended sequences of symbols, often presented in natural language. In this work, we aim to harness the extensive long-term reasoning, natural language comprehension, and the available prior knowledge of LLMs for increased resilience and adaptation in autonomous mobile robots. We introduce REAL, an approach for REsilience and Adaptation using LLMs. REAL provides a strategy to employ LLMs as a part of the mission planning and control framework of an autonomous robot. The LLM employed by REAL provides (i) a source of prior knowledge to increase resilience for challenging scenarios that the system had not been explicitly designed for; (ii) a way to interpret natural-language and other log/diagnostic information available in the autonomy stack, for mission planning; (iii) a way to adapt the control inputs using minimal user-provided prior knowledge about the dynamics/kinematics of the robot. We integrate REAL in the autonomy stack of a real multirotor, querying onboard an offboard LLM at 0.1-1.0 Hz as part the robot's mission planning and control feedback loops. We demonstrate in real-world experiments the ability of the LLM to reduce the position tracking errors of a multirotor under the presence of (i) errors in the parameters of the controller and (ii) unmodeled dynamics. We also show (iii) decision making to avoid potentially dangerous scenarios (e.g., robot oscillates) that had not been explicitly accounted for in the initial prompt design.

Recommender models excel at providing domain-specific item recommendations by leveraging extensive user behavior data. Despite their ability to act as lightweight domain experts, they struggle to perform versatile tasks such as providing explanations and engaging in conversations. On the other hand, large language models (LLMs) represent a significant step towards artificial general intelligence, showcasing remarkable capabilities in instruction comprehension, commonsense reasoning, and human interaction. However, LLMs lack the knowledge of domain-specific item catalogs and behavioral patterns, particularly in areas that diverge from general world knowledge, such as online e-commerce. Finetuning LLMs for each domain is neither economic nor efficient. In this paper, we bridge the gap between recommender models and LLMs, combining their respective strengths to create a versatile and interactive recommender system. We introduce an efficient framework called InteRecAgent, which employs LLMs as the brain and recommender models as tools. We first outline a minimal set of essential tools required to transform LLMs into InteRecAgent. We then propose an efficient workflow within InteRecAgent for task execution, incorporating key components such as a memory bus, dynamic demonstration-augmented task planning, and reflection. InteRecAgent enables traditional recommender systems, such as those ID-based matrix factorization models, to become interactive systems with a natural language interface through the integration of LLMs. Experimental results on several public datasets show that InteRecAgent achieves satisfying performance as a conversational recommender system, outperforming general-purpose LLMs.

The cultivation of expertise for large language models (LLMs) to solve tasks of specific areas often requires special-purpose tuning with calibrated behaviors on the expected stable outputs. To avoid huge cost brought by manual preparation of instruction datasets and training resources up to hundreds of hours, the exploitation of open knowledge including a wealth of low rank adaptation (LoRA) models and instruction datasets serves as a good starting point. However, existing methods on model and data selection focus on the performance of general-purpose capabilities while neglecting the knowledge gap exposed in domain-specific deployment. In the present study, we propose to bridge such gap by introducing few human-annotated samples (i.e., K-shot) for advancing task expertise of LLMs with open knowledge. Specifically, we develop an efficient and scalable pipeline to cost-efficiently produce task experts where K-shot data intervene in selecting the most promising expert candidates and the task-relevant instructions. A mixture-of-expert (MoE) system is built to make the best use of individual-yet-complementary knowledge between multiple experts. We unveil the two keys to the success of a MoE system, 1) the abidance by K-shot, and 2) the insistence on diversity. For the former, we ensure that models that truly possess problem-solving abilities on K-shot are selected rather than those blind guessers. Besides, during data selection, instructions that share task-relevant contexts with K-shot are prioritized. For the latter, we highlight the diversity of constituting experts and that of the fine-tuning instructions throughout the model and data selection process. Extensive experimental results confirm the superiority of our approach over existing methods on utilization of open knowledge across various tasks. Codes and models will be released later.

Large Language Models (LLMs) have demonstrated remarkable versatility in recent years, offering potential applications across specialized domains such as healthcare and medicine. Despite the availability of various open-source LLMs tailored for health contexts, adapting general-purpose LLMs to the medical domain presents significant challenges. In this paper, we introduce BioMistral, an open-source LLM tailored for the biomedical domain, utilizing Mistral as its foundation model and further pre-trained on PubMed Central. We conduct a comprehensive evaluation of BioMistral on a benchmark comprising 10 established medical question-answering (QA) tasks in English. We also explore lightweight models obtained through quantization and model merging approaches. Our results demonstrate BioMistral's superior performance compared to existing open-source medical models and its competitive edge against proprietary counterparts. Finally, to address the limited availability of data beyond English and to assess the multilingual generalization of medical LLMs, we automatically translated and evaluated this benchmark into 7 other languages. This marks the first large-scale multilingual evaluation of LLMs in the medical domain. Datasets, multilingual evaluation benchmarks, scripts, and all the models obtained during our experiments are freely released.

Large language models exhibit uneven performance across languages, with substantial gaps between high- and low-resource languages. We present a framework for enhancing monolingual capabilities of LLMs in underrepresented languages while preserving their general-purpose performance through targeted fine-tuning of language-specific subnetworks. Our approach identifies language-specific neurons using Language Activation Probability Entropy and fine-tunes only the weights associated with these neurons, a dedicated subnetwork, on target-language data. Experiments on Llama-3.1-8B and Mistral-Nemo-12B across 12 mid- and low-resource languages demonstrate that our method consistently outperforms full fine-tuning, FFN-only fine-tuning, LoRA adaptation, and random subset fine-tuning baselines while efficiently updating only up to 1% of model parameters. Beyond performance improvements, we observe enhanced favorable training dynamics, cross-lingual representational alignment, and systematic weight update changes. To facilitate future research, we release language-specific neuron identifications for over 100 languages as well as our adaptation pipeline, offering a cost-effective pathway for adapting state-of-the-art models to underrepresented languages.

Optimizing data mixtures for supervised fine-tuning (SFT) of large language models (LLMs) is critical for developing general-purpose models, yet this area remains underexplored. In this paper, we frame data mixing as an optimization problem and introduce a novel method designed to minimize validation loss. Our approach parametrizes the loss by modeling effective data transferred and leveraging scaling laws for fine-tuning. By experimenting with various small-scale data mixtures, we fit these parameters and derive the optimal weights. We provide both mathematical proofs and empirical results demonstrating that our algorithm achieves excellent overall and individual performance across all domains. Through controlled experiments, we show that models trained with our optimized weights perform on par with those using optimal weights determined via grid search, with per-domain loss only 0.66% higher than the best domain loss from grid search on average. Additionally, we show that reweighting popular SFT datasets using our method improves both validation loss and downstream performance. Finally, we discuss how our method can generalize to guide data selection for domain-specific models and provide insights into SFT.

In this paper, we presented GraphOmni, a comprehensive benchmark framework for systematically evaluating the graph reasoning capabilities of LLMs. By analyzing critical dimensions, including graph types, serialization formats, and prompt schemes, we provided extensive insights into the strengths and limitations of current LLMs. Our empirical findings emphasize that no single serialization or prompting strategy consistently outperforms others. Motivated by these insights, we propose a reinforcement learning-based approach that dynamically selects the best serialization-prompt pairings, resulting in significant accuracy improvements. GraphOmni's modular and extensible design establishes a robust foundation for future research, facilitating advancements toward general-purpose graph reasoning models.

This paper presents a comprehensive survey of the taxonomy and evolution of multimodal foundation models that demonstrate vision and vision-language capabilities, focusing on the transition from specialist models to general-purpose assistants. The research landscape encompasses five core topics, categorized into two classes. (i) We start with a survey of well-established research areas: multimodal foundation models pre-trained for specific purposes, including two topics -- methods of learning vision backbones for visual understanding and text-to-image generation. (ii) Then, we present recent advances in exploratory, open research areas: multimodal foundation models that aim to play the role of general-purpose assistants, including three topics -- unified vision models inspired by large language models (LLMs), end-to-end training of multimodal LLMs, and chaining multimodal tools with LLMs. The target audiences of the paper are researchers, graduate students, and professionals in computer vision and vision-language multimodal communities who are eager to learn the basics and recent advances in multimodal foundation models.

Large language models (LLMs) show excellent performance but are compute- and memory-intensive. Quantization can reduce memory and accelerate inference. However, existing methods cannot maintain accuracy and hardware efficiency at the same time. We propose SmoothQuant, a training-free, accuracy-preserving, and general-purpose post-training quantization (PTQ) solution to enable 8-bit weight, 8-bit activation (W8A8) quantization for LLMs. Based on the fact that weights are easy to quantize while activations are not, SmoothQuant smooths the activation outliers by offline migrating the quantization difficulty from activations to weights with a mathematically equivalent transformation. SmoothQuant enables an INT8 quantization of both weights and activations for all the matrix multiplications in LLMs, including OPT, BLOOM, GLM, MT-NLG, and LLaMA family. We demonstrate up to 1.56x speedup and 2x memory reduction for LLMs with negligible loss in accuracy. SmoothQuant enables serving 530B LLM within a single node. Our work offers a turn-key solution that reduces hardware costs and democratizes LLMs. Code is available at https://github.com/mit-han-lab/smoothquant.

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve patient outcomes. Considering this rapid technical progress, in this survey, we trace the recent advances of Medical Large Language Models (Med-LLMs), including the background, key findings, and mainstream techniques, especially for the evolution from general-purpose models to medical-specialized applications. Firstly, we delve into the foundational technology of Med-LLMs, indicating how general models can be progressively adapted and refined for the complicated medical tasks. Secondly, the wide-ranging applications of Med-LLMs are investigated across various healthcare domains, as well as an up-to-date review of existing Med-LLMs. The transformative impact of these models on daily medical practice is evident through their ability to assist clinicians, educators, and patients. Recognizing the importance of responsible innovation, we discuss the challenges associated with ensuring fairness, accountability, privacy, and robustness. Ethical considerations, rigorous evaluation methodologies, and the establishment of regulatory frameworks are crucial for building trustworthiness in the real-world system. We emphasize the need for ongoing scrutiny and development to maintain high standards of safety and reliability. Finally, we anticipate possible future trajectories for Med-LLMs, identifying key avenues for prudent expansion. By consolidating these insights, our review aims to provide professionals and researchers with a thorough understanding of the strengths and limitations of Med-LLMs, fostering a balanced and ethical approach to their integration into the healthcare ecosystem.

Designing high-quality educational questions is a challenging and time-consuming task. In this work, we propose a novel approach that utilizes prompt-based techniques to generate descriptive and reasoning-based questions. However, current question-answering (QA) datasets are inadequate for conducting our experiments on prompt-based question generation (QG) in an educational setting. Therefore, we curate a new QG dataset called EduProbe for school-level subjects, by leveraging the rich content of NCERT textbooks. We carefully annotate this dataset as quadruples of 1) Context: a segment upon which the question is formed; 2) Long Prompt: a long textual cue for the question (i.e., a longer sequence of words or phrases, covering the main theme of the context); 3) Short Prompt: a short textual cue for the question (i.e., a condensed representation of the key information or focus of the context); 4) Question: a deep question that aligns with the context and is coherent with the prompts. We investigate several prompt-based QG methods by fine-tuning pre-trained transformer-based large language models (LLMs), namely PEGASUS, T5, MBART, and BART. Moreover, we explore the performance of two general-purpose pre-trained LLMs such as Text-Davinci-003 and GPT-3.5-Turbo without any further training. By performing automatic evaluation, we show that T5 (with long prompt) outperforms all other models, but still falls short of the human baseline. Under human evaluation criteria, TextDavinci-003 usually shows better results than other models under various prompt settings. Even in the case of human evaluation criteria, QG models mostly fall short of the human baseline. Our code and dataset are available at: https://github.com/my625/PromptQG

Recently, growing interest has been aroused in extending the multimodal capability of large language models (LLMs), e.g., vision-language (VL) learning, which is regarded as the next milestone of artificial general intelligence. However, existing solutions are prohibitively expensive, which not only need to optimize excessive parameters, but also require another large-scale pre-training before VL instruction tuning. In this paper, we propose a novel and affordable solution for the effective VL adaption of LLMs, called Mixture-of-Modality Adaptation (MMA). Instead of using large neural networks to connect the image encoder and LLM, MMA adopts lightweight modules, i.e., adapters, to bridge the gap between LLMs and VL tasks, which also enables the joint optimization of the image and language models. Meanwhile, MMA is also equipped with a routing algorithm to help LLMs achieve an automatic shift between single- and multi-modal instructions without compromising their ability of natural language understanding. To validate MMA, we apply it to a recent LLM called LLaMA and term this formed large vision-language instructed model as LaVIN. To validate MMA and LaVIN, we conduct extensive experiments under two setups, namely multimodal science question answering and multimodal dialogue. The experimental results not only demonstrate the competitive performance and the superior training efficiency of LaVIN than existing multimodal LLMs, but also confirm its great potential as a general-purpose chatbot. More importantly, the actual expenditure of LaVIN is extremely cheap, e.g., only 1.4 training hours with 3.8M trainable parameters, greatly confirming the effectiveness of MMA. Our project is released at https://luogen1996.github.io/lavin.

Redacting Personally Identifiable Information (PII) from unstructured text is critical for ensuring data privacy in regulated domains. While earlier approaches have relied on rule-based systems and domain-specific Named Entity Recognition (NER) models, these methods fail to generalize across formats and contexts. Recent advances in Large Language Models (LLMs) offer a promising alternative, yet the effect of architectural and training choices on redaction performance remains underexplored. LLMs have demonstrated strong performance in tasks that require contextual language understanding, including the redaction of PII in free-form text. Prior work suggests that with appropriate adaptation, LLMs can become effective contextual privacy learners. However, the consequences of architectural and training choices for PII Redaction remain underexplored. In this work, we present a comprehensive analysis of LLMs as privacy-preserving PII Redaction systems. We evaluate a range of LLM architectures and training strategies for their effectiveness in PII Redaction. Our analysis measures redaction performance, semantic preservation, and PII leakage, and compares these outcomes against latency and computational cost. The results provide practical guidance for configuring LLM-based redactors that are accurate, efficient, and privacy-aware. To support reproducibility and real-world deployment, we release PRvL, an open-source suite of fine-tuned models, and evaluation tools for general-purpose PII Redaction. PRvL is built entirely on open-source LLMs and supports multiple inference settings for flexibility and compliance. It is designed to be easily customized for different domains and fully operable within secure, self-managed environments. This enables data owners to perform redactions without relying on third-party services or exposing sensitive content beyond their own infrastructure.

Urban and transportation research has long sought to uncover statistically meaningful relationships between key variables and societal outcomes such as road safety, to generate actionable insights that guide the planning, development, and renewal of urban and transportation systems. However, traditional workflows face several key challenges: (1) reliance on human experts to propose hypotheses, which is time-consuming and prone to confirmation bias; (2) limited interpretability, particularly in deep learning approaches; and (3) underutilization of unstructured data that can encode critical urban context. Given these limitations, we propose a Multimodal Large Language Model (MLLM)-based approach for interpretable hypothesis inference, enabling the automated generation, evaluation, and refinement of hypotheses concerning urban context and road safety outcomes. Our method leverages MLLMs to craft safety-relevant questions for street view images (SVIs), extract interpretable embeddings from their responses, and apply them in regression-based statistical models. UrbanX supports iterative hypothesis testing and refinement, guided by statistical evidence such as coefficient significance, thereby enabling rigorous scientific discovery of previously overlooked correlations between urban design and safety. Experimental evaluations on Manhattan street segments demonstrate that our approach outperforms pretrained deep learning models while offering full interpretability. Beyond road safety, UrbanX can serve as a general-purpose framework for urban scientific discovery, extracting structured insights from unstructured urban data across diverse socioeconomic and environmental outcomes. This approach enhances model trustworthiness for policy applications and establishes a scalable, statistically grounded pathway for interpretable knowledge discovery in urban and transportation studies.

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational overhead, requiring further domain expertise. Here, we introduce a token-optimized and robust Knowledge Graph-based Retrieval Augmented Generation (KG-RAG) framework by leveraging a massive biomedical KG (SPOKE) with LLMs such as Llama-2-13b, GPT-3.5-Turbo and GPT-4, to generate meaningful biomedical text rooted in established knowledge. Compared to the existing RAG technique for Knowledge Graphs, the proposed method utilizes minimal graph schema for context extraction and uses embedding methods for context pruning. This optimization in context extraction results in more than 50% reduction in token consumption without compromising the accuracy, making a cost-effective and robust RAG implementation on proprietary LLMs. KG-RAG consistently enhanced the performance of LLMs across diverse biomedical prompts by generating responses rooted in established knowledge, accompanied by accurate provenance and statistical evidence (if available) to substantiate the claims. Further benchmarking on human curated datasets, such as biomedical true/false and multiple-choice questions (MCQ), showed a remarkable 71% boost in the performance of the Llama-2 model on the challenging MCQ dataset, demonstrating the framework's capacity to empower open-source models with fewer parameters for domain specific questions. Furthermore, KG-RAG enhanced the performance of proprietary GPT models, such as GPT-3.5 and GPT-4. In summary, the proposed framework combines explicit and implicit knowledge of KG and LLM in a token optimized fashion, thus enhancing the adaptability of general-purpose LLMs to tackle domain-specific questions in a cost-effective fashion.

Large language models (LLMs) have demonstrated remarkable proficiency in understanding and generating human-like texts, which may potentially revolutionize the finance industry. However, existing LLMs often fall short in the financial field, which is mainly attributed to the disparities between general text data and financial text data. Unfortunately, there is only a limited number of financial text datasets available, and BloombergGPT, the first financial LLM (FinLLM), is close-sourced (only the training logs were released). In light of this, we aim to democratize Internet-scale financial data for LLMs, which is an open challenge due to diverse data sources, low signal-to-noise ratio, and high time-validity. To address the challenges, we introduce an open-sourced and data-centric framework, Financial Generative Pre-trained Transformer (FinGPT), that automates the collection and curation of real-time financial data from 34 diverse sources on the Internet, providing researchers and practitioners with accessible and transparent resources to develop their FinLLMs. Additionally, we propose a simple yet effective strategy for fine-tuning FinLLM using the inherent feedback from the market, dubbed Reinforcement Learning with Stock Prices (RLSP). We also adopt the Low-rank Adaptation (LoRA, QLoRA) method that enables users to customize their own FinLLMs from general-purpose LLMs at a low cost. Finally, we showcase several FinGPT applications, including robo-advisor, sentiment analysis for algorithmic trading, and low-code development. FinGPT aims to democratize FinLLMs, stimulate innovation, and unlock new opportunities in open finance. The codes have been open-sourced.

The information retrieval community has recently witnessed a revolution due to large pretrained transformer models. Another key ingredient for this revolution was the MS MARCO dataset, whose scale and diversity has enabled zero-shot transfer learning to various tasks. However, not all IR tasks and domains can benefit from one single dataset equally. Extensive research in various NLP tasks has shown that using domain-specific training data, as opposed to a general-purpose one, improves the performance of neural models. In this work, we harness the few-shot capabilities of large pretrained language models as synthetic data generators for IR tasks. We show that models finetuned solely on our unsupervised dataset outperform strong baselines such as BM25 as well as recently proposed self-supervised dense retrieval methods. Furthermore, retrievers finetuned on both supervised and our synthetic data achieve better zero-shot transfer than models finetuned only on supervised data. Code, models, and data are available at https://github.com/zetaalphavector/inpars .

The recent improvement in code generation capabilities due to the use of large language models has mainly benefited general purpose programming languages. Domain specific languages, such as the ones used for IT Automation, have received far less attention, despite involving many active developers and being an essential component of modern cloud platforms. This work focuses on the generation of Ansible-YAML, a widely used markup language for IT Automation. We present Ansible Wisdom, a natural-language to Ansible-YAML code generation tool, aimed at improving IT automation productivity. Ansible Wisdom is a transformer-based model, extended by training with a new dataset containing Ansible-YAML. We also develop two novel performance metrics for YAML and Ansible to capture the specific characteristics of this domain. Results show that Ansible Wisdom can accurately generate Ansible script from natural language prompts with performance comparable or better than existing state of the art code generation models.

The rapid development of Large Language Models (LLMs) in vertical domains, including intellectual property (IP), lacks a specific evaluation benchmark for assessing their understanding, application, and reasoning abilities. To fill this gap, we introduce IPEval, the first evaluation benchmark tailored for IP agency and consulting tasks. IPEval comprises 2657 multiple-choice questions across four major dimensions: creation, application, protection, and management of IP. These questions span patent rights (inventions, utility models, designs), trademarks, copyrights, trade secrets, and other related laws. Evaluation methods include zero-shot, 5-few-shot, and Chain of Thought (CoT) for seven LLM types, predominantly in English or Chinese. Results show superior English performance by models like GPT series and Qwen series, while Chinese-centric LLMs excel in Chinese tests, albeit specialized IP LLMs lag behind general-purpose ones. Regional and temporal aspects of IP underscore the need for LLMs to grasp legal nuances and evolving laws. IPEval aims to accurately gauge LLM capabilities in IP and spur development of specialized models. Website: https://ipeval.github.io/

Process Reward Models (PRMs) have emerged as a promising framework for supervising intermediate reasoning in large language models (LLMs), yet existing PRMs are primarily trained on general or Science, Technology, Engineering, and Mathematics (STEM) domains and fall short in domain-specific contexts such as finance, where reasoning is more structured, symbolic, and sensitive to factual and regulatory correctness. We introduce Fin-PRM, a domain-specialized, trajectory-aware PRM tailored to evaluate intermediate reasoning steps in financial tasks. Fin-PRM integrates step-level and trajectory-level reward supervision, enabling fine-grained evaluation of reasoning traces aligned with financial logic. We apply Fin-PRM in both offline and online reward learning settings, supporting three key applications: (i) selecting high-quality reasoning trajectories for distillation-based supervised fine-tuning, (ii) providing dense process-level rewards for reinforcement learning, and (iii) guiding reward-informed Best-of-N inference at test time. Experimental results on financial reasoning benchmarks, including CFLUE and FinQA, demonstrate that Fin-PRM consistently outperforms general-purpose PRMs and strong domain baselines in trajectory selection quality. Downstream models trained with Fin-PRM yield substantial improvements with baselines, with gains of 12.9\% in supervised learning, 5.2\% in reinforcement learning, and 5.1\% in test-time performance. These findings highlight the value of domain-specialized reward modeling for aligning LLMs with expert-level financial reasoning. Our project resources will be available at https://github.com/aliyun/qwen-dianjin.

Nowadays, developers increasingly rely on solutions powered by Large Language Models (LLM) to assist them with their coding tasks. This makes it crucial to align these tools with human values to prevent malicious misuse. In this paper, we propose a comprehensive framework for assessing the potential harmfulness of LLMs within the software engineering domain. We begin by developing a taxonomy of potentially harmful software engineering scenarios and subsequently, create a dataset of prompts based on this taxonomy. To systematically assess the responses, we design and validate an automatic evaluator that classifies the outputs of a variety of LLMs both open-source and closed-source models, as well as general-purpose and code-specific LLMs. Furthermore, we investigate the impact of models size, architecture family, and alignment strategies on their tendency to generate harmful content. The results show significant disparities in the alignment of various LLMs for harmlessness. We find that some models and model families, such as Openhermes, are more harmful than others and that code-specific models do not perform better than their general-purpose counterparts. Notably, some fine-tuned models perform significantly worse than their base-models due to their design choices. On the other side, we find that larger models tend to be more helpful and are less likely to respond with harmful information. These results highlight the importance of targeted alignment strategies tailored to the unique challenges of software engineering tasks and provide a foundation for future work in this critical area.

Recent advances in large language models (LLMs) have demonstrated exceptional performance in various natural language processing (NLP) tasks. However, their effective application in the medical domain is hampered by a lack of medical domain knowledge. In this study, we present SA-MDKIF, a scalable and adaptable framework that aims to inject medical knowledge into general-purpose LLMs through instruction tuning, thereby enabling adaptability for various downstream tasks. SA-MDKIF consists of two stages: skill training and skill adaptation. In the first stage, we define 12 basic medical skills and use AdaLoRA to train these skills based on uniformly formatted instructional datasets that we have constructed. In the next stage, we train the skill router using task-specific downstream data and use this router to integrate the acquired skills with LLMs during inference. Experimental results on 9 different medical tasks show that SA-MDKIF improves performance by 10-20% compared to the original LLMs. Notably, this improvement is particularly pronounced for unseen medical tasks, showing an improvement of up to 30%.

Video anomaly detection (VAD) is essential for enhancing safety and security by identifying unusual events across different environments. Existing VAD benchmarks, however, are primarily designed for general-purpose scenarios, neglecting the specific characteristics of smart home applications. To bridge this gap, we introduce SmartHome-Bench, the first comprehensive benchmark specially designed for evaluating VAD in smart home scenarios, focusing on the capabilities of multi-modal large language models (MLLMs). Our newly proposed benchmark consists of 1,203 videos recorded by smart home cameras, organized according to a novel anomaly taxonomy that includes seven categories, such as Wildlife, Senior Care, and Baby Monitoring. Each video is meticulously annotated with anomaly tags, detailed descriptions, and reasoning. We further investigate adaptation methods for MLLMs in VAD, assessing state-of-the-art closed-source and open-source models with various prompting techniques. Results reveal significant limitations in the current models' ability to detect video anomalies accurately. To address these limitations, we introduce the Taxonomy-Driven Reflective LLM Chain (TRLC), a new LLM chaining framework that achieves a notable 11.62% improvement in detection accuracy. The benchmark dataset and code are publicly available at https://github.com/Xinyi-0724/SmartHome-Bench-LLM.

The advent of Large Language Models (LLMs) has paved the way for complex tasks such as role-playing, which enhances user interactions by enabling models to imitate various characters. However, the closed-source nature of state-of-the-art LLMs and their general-purpose training limit role-playing optimization. In this paper, we introduce RoleLLM, a framework to benchmark, elicit, and enhance role-playing abilities in LLMs. RoleLLM comprises four stages: (1) Role Profile Construction for 100 roles; (2) Context-Based Instruction Generation (Context-Instruct) for role-specific knowledge extraction; (3) Role Prompting using GPT (RoleGPT) for speaking style imitation; and (4) Role-Conditioned Instruction Tuning (RoCIT) for fine-tuning open-source models along with role customization. By Context-Instruct and RoleGPT, we create RoleBench, the first systematic and fine-grained character-level benchmark dataset for role-playing with 168,093 samples. Moreover, RoCIT on RoleBench yields RoleLLaMA (English) and RoleGLM (Chinese), significantly enhancing role-playing abilities and even achieving comparable results with RoleGPT (using GPT-4).

We show that reinforcement learning applied to large language models (LLMs) significantly boosts performance on complex coding and reasoning tasks. Additionally, we compare two general-purpose reasoning models - OpenAI o1 and an early checkpoint of o3 - with a domain-specific system, o1-ioi, which uses hand-engineered inference strategies designed for competing in the 2024 International Olympiad in Informatics (IOI). We competed live at IOI 2024 with o1-ioi and, using hand-crafted test-time strategies, placed in the 49th percentile. Under relaxed competition constraints, o1-ioi achieved a gold medal. However, when evaluating later models such as o3, we find that o3 achieves gold without hand-crafted domain-specific strategies or relaxed constraints. Our findings show that although specialized pipelines such as o1-ioi yield solid improvements, the scaled-up, general-purpose o3 model surpasses those results without relying on hand-crafted inference heuristics. Notably, o3 achieves a gold medal at the 2024 IOI and obtains a Codeforces rating on par with elite human competitors. Overall, these results indicate that scaling general-purpose reinforcement learning, rather than relying on domain-specific techniques, offers a robust path toward state-of-the-art AI in reasoning domains, such as competitive programming.

Recent advancements in machine learning and natural language processing have led to the rapid development of artificial intelligence (AI) as a valuable tool in the healthcare industry. Using large language models (LLMs) as conversational agents or chatbots has the potential to assist doctors in diagnosing patients, detecting early symptoms of diseases, and providing health advice to patients. This paper focuses on the role of chatbots in healthcare and explores the use of avatars to make AI interactions more appealing to patients. A framework of a general-purpose AI avatar application is demonstrated by using a three-category prompt dictionary and prompt improvement mechanism. A two-phase approach is suggested to fine-tune a general-purpose AI language model and create different AI avatars to discuss medical issues with users. Prompt engineering enhances the chatbot's conversational abilities and personality traits, fostering a more human-like interaction with patients. Ultimately, the injection of personality into the chatbot could potentially increase patient engagement. Future directions for research include investigating ways to improve chatbots' understanding of context and ensuring the accuracy of their outputs through fine-tuning with specialized medical data sets.

Multimodal Large Language Models (MLLMs) equipped with step-by-step thinking capabilities have demonstrated remarkable performance on complex reasoning problems. However, this thinking process is redundant for simple problems solvable without complex reasoning. To address this inefficiency, we propose R-4B, an auto-thinking MLLM, which can adaptively decide when to think based on problem complexity. The central idea of R-4B is to empower the model with both thinking and non-thinking capabilities using bi-mode annealing, and apply Bi-mode Policy Optimization~(BPO) to improve the model's accuracy in determining whether to activate the thinking process. Specifically, we first train the model on a carefully curated dataset spanning various topics, which contains samples from both thinking and non-thinking modes. Then it undergoes a second phase of training under an improved GRPO framework, where the policy model is forced to generate responses from both modes for each input query. Experimental results show that R-4B achieves state-of-the-art performance across 25 challenging benchmarks. It outperforms Qwen2.5-VL-7B in most tasks and achieves performance comparable to larger models such as Kimi-VL-A3B-Thinking-2506 (16B) on reasoning-intensive benchmarks with lower computational cost.

While large language models (LLMs) have recently demonstrated strong potential in solving planning problems, there is a trade-off between flexibility and complexity. LLMs, as zero-shot planners themselves, are still not capable of directly generating valid plans for complex planning problems such as multi-constraint or long-horizon tasks. On the other hand, many frameworks aiming to solve complex planning problems often rely on task-specific preparatory efforts, such as task-specific in-context examples and pre-defined critics/verifiers, which limits their cross-task generalization capability. In this paper, we tackle these challenges by observing that the core of many planning problems lies in optimization problems: searching for the optimal solution (best plan) with goals subject to constraints (preconditions and effects of decisions). With LLMs' commonsense, reasoning, and programming capabilities, this opens up the possibilities of a universal LLM-based approach to planning problems. Inspired by this observation, we propose LLMFP, a general-purpose framework that leverages LLMs to capture key information from planning problems and formally formulate and solve them as optimization problems from scratch, with no task-specific examples needed. We apply LLMFP to 9 planning problems, ranging from multi-constraint decision making to multi-step planning problems, and demonstrate that LLMFP achieves on average 83.7% and 86.8% optimal rate across 9 tasks for GPT-4o and Claude 3.5 Sonnet, significantly outperforming the best baseline (direct planning with OpenAI o1-preview) with 37.6% and 40.7% improvements. We also validate components of LLMFP with ablation experiments and analyzed the underlying success and failure reasons.

Large Language Models (LLMs) are general-purpose tools with wide-ranging applications, including in materials science. In this work, we introduce aLLoyM, a fine-tuned LLM specifically trained on alloy compositions, temperatures, and their corresponding phase information. To develop aLLoyM, we curated question-and-answer (Q&A) pairs for binary and ternary phase diagrams using the open-source Computational Phase Diagram Database (CPDDB) and assessments based on CALPHAD (CALculation of PHAse Diagrams). We fine-tuned Mistral, an open-source pre-trained LLM, for two distinct Q&A formats: multiple-choice and short-answer. Benchmark evaluations demonstrate that fine-tuning substantially enhances performance on multiple-choice phase diagram questions. Moreover, the short-answer model of aLLoyM exhibits the ability to generate novel phase diagrams from its components alone, underscoring its potential to accelerate the discovery of previously unexplored materials systems. To promote further research and adoption, we have publicly released the short-answer fine-tuned version of aLLoyM, along with the complete benchmarking Q&A dataset, on Hugging Face.

The most recent large language models such as ChatGPT and GPT-4 have garnered significant attention, as they are capable of generating high-quality responses to human input. Despite the extensive testing of ChatGPT and GPT-4 on generic text corpora, showcasing their impressive capabilities, a study focusing on financial corpora has not been conducted. In this study, we aim to bridge this gap by examining the potential of ChatGPT and GPT-4 as a solver for typical financial text analytic problems in the zero-shot or few-shot setting. Specifically, we assess their capabilities on four representative tasks over five distinct financial textual datasets. The preliminary study shows that ChatGPT and GPT-4 struggle on tasks such as financial named entity recognition (NER) and sentiment analysis, where domain-specific knowledge is required, while they excel in numerical reasoning tasks. We report both the strengths and limitations of the current versions of ChatGPT and GPT-4, comparing them to the state-of-the-art finetuned models as well as pretrained domain-specific generative models. Our experiments provide qualitative studies, through which we hope to help understand the capability of the existing models and facilitate further improvements.

Large language models (LLMs) possess broad world knowledge and strong general-purpose reasoning ability, yet they struggle to learn from many in-context examples on standard machine learning (ML) tasks, that is, to leverage many-shot demonstrations purely via in-context learning (ICL) without gradient descent. We introduce MachineLearningLM, a portable continued-pretraining framework that equips a general-purpose LLM with robust in-context ML capability while preserving its general knowledge and reasoning for broader chat workflows. Our pretraining procedure synthesizes ML tasks from millions of structural causal models (SCMs), spanning shot counts up to 1,024. We begin with a random-forest teacher, distilling tree-based decision strategies into the LLM to strengthen robustness in numerical modeling. All tasks are serialized with a token-efficient prompt, enabling 3x to 6x more examples per context window and delivering up to 50x amortized throughput via batch inference. Despite a modest setup (Qwen-2.5-7B-Instruct with LoRA rank 8), MachineLearningLM outperforms strong LLM baselines (e.g., GPT-5-mini) by an average of about 15% on out-of-distribution tabular classification across finance, physics, biology, and healthcare domains. It exhibits a striking many-shot scaling law: accuracy increases monotonically as in-context demonstrations grow from 8 to 1,024. Without any task-specific training, it attains random-forest-level accuracy across hundreds of shots. General chat capabilities, including knowledge and reasoning, are preserved: it achieves 75.4% on MMLU.

Large Language Models (LLMs) have demonstrated remarkable proficiency in understanding and generating natural language. However, their capabilities wane in highly specialized domains underrepresented in the pretraining corpus, such as physical and biomedical sciences. This work explores how to repurpose general LLMs into effective task solvers for specialized domains. We introduce a novel, model-agnostic framework for learning custom input tags, which are parameterized as continuous vectors appended to the LLM's embedding layer, to condition the LLM. We design two types of input tags: domain tags are used to delimit specialized representations (e.g., chemical formulas) and provide domain-relevant context; function tags are used to represent specific functions (e.g., predicting molecular properties) and compress function-solving instructions. We develop a three-stage protocol to learn these tags using auxiliary data and domain knowledge. By explicitly disentangling task domains from task functions, our method enables zero-shot generalization to unseen problems through diverse combinations of the input tags. It also boosts LLM's performance in various specialized domains, such as predicting protein or chemical properties and modeling drug-target interactions, outperforming expert models tailored to these tasks.

Large language models are often used to answer queries grounded in large text corpora (e.g. codebases, legal documents, or chat histories) by placing the entire corpus in the context window and leveraging in-context learning (ICL). Although current models support contexts of 100K-1M tokens, this setup is costly to serve because the memory consumption of the KV cache scales with input length. We explore an alternative: training a smaller KV cache offline on each corpus. At inference time, we load this trained KV cache, which we call a Cartridge, and decode a response. Critically, the cost of training a Cartridge can be amortized across all the queries referencing the same corpus. However, we find that the naive approach of training the Cartridge with next-token prediction on the corpus is not competitive with ICL. Instead, we propose self-study, a training recipe in which we generate synthetic conversations about the corpus and train the Cartridge with a context-distillation objective. We find that Cartridges trained with self-study replicate the functionality of ICL, while being significantly cheaper to serve. On challenging long-context benchmarks, Cartridges trained with self-study match ICL performance while using 38.6x less memory and enabling 26.4x higher throughput. Self-study also extends the model's effective context length (e.g. from 128k to 484k tokens on MTOB) and surprisingly, leads to Cartridges that can be composed at inference time without retraining.

Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of biomedically fine-tuned LLMs against their general-purpose counterparts on a variety of clinical tasks. We evaluated their performance on clinical case challenges from the New England Journal of Medicine (NEJM) and the Journal of the American Medical Association (JAMA) and on several clinical tasks (e.g., information extraction, document summarization, and clinical coding). Using benchmarks specifically chosen to be likely outside the fine-tuning datasets of biomedical models, we found that biomedical LLMs mostly perform inferior to their general-purpose counterparts, especially on tasks not focused on medical knowledge. While larger models showed similar performance on case tasks (e.g., OpenBioLLM-70B: 66.4% vs. Llama-3-70B-Instruct: 65% on JAMA cases), smaller biomedical models showed more pronounced underperformance (e.g., OpenBioLLM-8B: 30% vs. Llama-3-8B-Instruct: 64.3% on NEJM cases). Similar trends were observed across the CLUE (Clinical Language Understanding Evaluation) benchmark tasks, with general-purpose models often performing better on text generation, question answering, and coding tasks. Our results suggest that fine-tuning LLMs to biomedical data may not provide the expected benefits and may potentially lead to reduced performance, challenging prevailing assumptions about domain-specific adaptation of LLMs and highlighting the need for more rigorous evaluation frameworks in healthcare AI. Alternative approaches, such as retrieval-augmented generation, may be more effective in enhancing the biomedical capabilities of LLMs without compromising their general knowledge.

Large language models (LLMs) have demonstrated strong performance in general-purpose machine translation, but their effectiveness in complex, domain-sensitive translation tasks remains underexplored. Recent advancements in Large Reasoning Models (LRMs), raise the question of whether structured reasoning can enhance translation quality across diverse domains. In this work, we compare the performance of LRMs with traditional LLMs across 15 representative domains and four translation directions. Our evaluation considers various factors, including task difficulty, input length, and terminology density. We use a combination of automatic metrics and an enhanced MQM-based evaluation hierarchy to assess translation quality. Our findings show that LRMs consistently outperform traditional LLMs in semantically complex domains, especially in long-text and high-difficulty translation scenarios. Moreover, domain-adaptive prompting strategies further improve performance by better leveraging the reasoning capabilities of LRMs. These results highlight the potential of structured reasoning in MDMT tasks and provide valuable insights for optimizing translation systems in domain-sensitive contexts.

Proving mathematical theorems using computer-verifiable formal languages like Lean significantly impacts mathematical reasoning. One approach to formal theorem proving involves generating complete proofs using Large Language Models (LLMs) based on Natural Language (NL) proofs. Similar methods have shown promising results in code generation. However, most modern LLMs exhibit suboptimal performance due to the scarcity of aligned NL and Formal Language (FL) theorem-proving data. This scarcity results in a paucity of methodologies for training LLMs and techniques to fully utilize their capabilities in composing formal proofs. To address the challenges, this paper proposes **TheoremLlama**, an end-to-end framework to train a general-purpose LLM to become a Lean4 expert. This framework encompasses NL-FL aligned dataset generation methods, training approaches for the LLM formal theorem prover, and techniques for LLM Lean4 proof writing. Using the dataset generation method, we provide *Open Bootstrapped Theorems* (OBT), an NL-FL aligned and bootstrapped dataset. A key innovation in this framework is the NL-FL bootstrapping method, where NL proofs are integrated into Lean4 code for training datasets, leveraging the NL reasoning ability of LLMs for formal reasoning. The **TheoremLlama** framework achieves cumulative accuracies of 36.48% and 33.61% on MiniF2F-Valid and Test datasets respectively, surpassing the GPT-4 baseline of 22.95% and 25.41%. We have also open-sourced our model checkpoints and generated dataset, and will soon make all the code publicly available.

Given the broad capabilities of large language models, it should be possible to work towards a general-purpose, text-based assistant that is aligned with human values, meaning that it is helpful, honest, and harmless. As an initial foray in this direction we study simple baseline techniques and evaluations, such as prompting. We find that the benefits from modest interventions increase with model size, generalize to a variety of alignment evaluations, and do not compromise the performance of large models. Next we investigate scaling trends for several training objectives relevant to alignment, comparing imitation learning, binary discrimination, and ranked preference modeling. We find that ranked preference modeling performs much better than imitation learning, and often scales more favorably with model size. In contrast, binary discrimination typically performs and scales very similarly to imitation learning. Finally we study a `preference model pre-training' stage of training, with the goal of improving sample efficiency when finetuning on human preferences.

Recent researches of large language models(LLM), which is pre-trained on massive general-purpose corpora, have achieved breakthroughs in responding human queries. However, these methods face challenges including limited data insufficiency to support extensive pre-training and can not align responses with users' instructions. To address these issues, we introduce a medical instruction dataset, CMedINS, containing six medical instructions derived from actual medical tasks, which effectively fine-tunes LLM in conjunction with other data. Subsequently, We launch our medical model, IIMedGPT, employing an efficient preference alignment method, Direct preference Optimization(DPO). The results show that our final model outperforms existing medical models in medical dialogue.Datsets, Code and model checkpoints will be released upon acceptance.

Recent studies have demonstrated the effectiveness of Large Language Models (LLMs) as reasoning modules that can deconstruct complex tasks into more manageable sub-tasks, particularly when applied to visual reasoning tasks for images. In contrast, this paper introduces a Video Understanding and Reasoning Framework (VURF) based on the reasoning power of LLMs. Ours is a novel approach to extend the utility of LLMs in the context of video tasks, leveraging their capacity to generalize from minimal input and output demonstrations within a contextual framework. By presenting LLMs with pairs of instructions and their corresponding high-level programs, we harness their contextual learning capabilities to generate executable visual programs for video understanding. To enhance program's accuracy and robustness, we implement two important strategies. Firstly, we employ a feedback-generation approach, powered by GPT-3.5, to rectify errors in programs utilizing unsupported functions. Secondly, taking motivation from recent works on self refinement of LLM outputs, we introduce an iterative procedure for improving the quality of the in-context examples by aligning the initial outputs to the outputs that would have been generated had the LLM not been bound by the structure of the in-context examples. Our results on several video-specific tasks, including visual QA, video anticipation, pose estimation and multi-video QA illustrate the efficacy of these enhancements in improving the performance of visual programming approaches for video tasks. Our Codes and data will be publicly released.

The remarkable success of Large Language Models (LLMs) and instruction tuning drives the evolution of Vision Language Models (VLMs) towards a versatile general-purpose model. Yet, it remains unexplored whether current VLMs genuinely possess quality object-level image understanding capabilities determined from 'what objects are in the image?' or 'which object corresponds to a specified bounding box?'. Our findings reveal that the image understanding capabilities of current VLMs are strongly correlated with their zero-shot performance on Vision Language (VL) tasks. This suggests that prioritizing basic image understanding is crucial for VLMs to excel at VL tasks. To enhance object-level image understanding, we propose Crayon Large Language and Vision mOdel (CoLLaVO), which incorporates instruction tuning with crayon prompt as a new visual prompt tuning scheme based on panoptic color maps. Furthermore, we present a learning strategy of Dual QLoRA to preserve object-level image understanding without forgetting it during visual instruction tuning, thereby achieving a significant leap in zero-shot numerous VL benchmarks.

Recent advancements in 3D Large Language Models (3DLLMs) have highlighted their potential in building general-purpose agents in the 3D real world, yet challenges remain due to the lack of high-quality robust instruction-following data, leading to limited discriminative power and generalization of 3DLLMs. In this paper, we introduce Robin3D, a powerful 3DLLM trained on large-scale instruction-following data generated by our novel data engine, Robust Instruction Generation (RIG) engine. RIG generates two key instruction data: 1) the Adversarial Instruction-following data, which features mixed negative and positive samples to enhance the model's discriminative understanding. 2) the Diverse Instruction-following data, which contains various instruction styles to enhance model's generalization. As a result, we construct 1 million instruction-following data, consisting of 344K Adversarial samples, 508K Diverse samples, and 165K benchmark training set samples. To better handle these complex instructions, Robin3D first incorporates Relation-Augmented Projector to enhance spatial understanding, and then strengthens the object referring and grounding ability through ID-Feature Bonding. Robin3D consistently outperforms previous methods across five widely-used 3D multimodal learning benchmarks, without the need for task-specific fine-tuning. Notably, we achieve a 7.8\% improvement in the grounding task (Multi3DRefer) and a 6.9\% improvement in the captioning task (Scan2Cap).

Medical question-answering (QA) is a critical task for evaluating how effectively large language models (LLMs) encode clinical knowledge and assessing their potential applications in medicine. Despite showing promise on multiple-choice tests, LLMs frequently struggle with open-ended medical questions, producing responses with dangerous hallucinations or lacking comprehensive coverage of critical aspects. Existing approaches attempt to address these challenges through domain-specific fine-tuning, but this proves resource-intensive and difficult to scale across models. To improve the comprehensiveness and factuality of medical responses, we propose a novel approach utilizing structured medical reasoning. Our method guides LLMs through an seven-step cognitive process inspired by clinical diagnosis, enabling more accurate and complete answers without additional training. Experiments on the MedLFQA benchmark demonstrate that our approach achieves the highest Factuality Score of 85.8, surpassing fine-tuned models. Notably, this improvement transfers to smaller models, highlighting the method's efficiency and scalability. Our code and datasets are available.

Despite significant advancements in general-purpose AI agents, several challenges still hinder their practical application in real-world scenarios. First, the limited planning capabilities of Large Language Models (LLM) restrict AI agents from effectively solving complex tasks that require long-horizon planning. Second, general-purpose AI agents struggle to efficiently utilize domain-specific knowledge and human expertise. In this paper, we introduce the Standard Operational Procedure-guided Agent (SOP-agent), a novel framework for constructing domain-specific agents through pseudocode-style Standard Operational Procedures (SOPs) written in natural language. Formally, we represent a SOP as a decision graph, which is traversed to guide the agent in completing tasks specified by the SOP. We conduct extensive experiments across tasks in multiple domains, including decision-making, search and reasoning, code generation, data cleaning, and grounded customer service. The SOP-agent demonstrates excellent versatility, achieving performance superior to general-purpose agent frameworks and comparable to domain-specific agent systems. Additionally, we introduce the Grounded Customer Service Benchmark, the first benchmark designed to evaluate the grounded decision-making capabilities of AI agents in customer service scenarios based on SOPs.

Multimodal Large Language Models (MLLMs) have recently sparked significant interest, which demonstrates emergent capabilities to serve as a general-purpose model for various vision-language tasks. However, existing methods mainly focus on limited types of instructions with a single image as visual context, which hinders the widespread availability of MLLMs. In this paper, we introduce the I4 benchmark to comprehensively evaluate the instruction following ability on complicated interleaved vision-language instructions, which involve intricate image-text sequential context, covering a diverse range of scenarios (e.g., visually-rich webpages/textbooks, lecture slides, embodied dialogue). Systematic evaluation on our I4 benchmark reveals a common defect of existing methods: the Visual Prompt Generator (VPG) trained on image-captioning alignment objective tends to attend to common foreground information for captioning but struggles to extract specific information required by particular tasks. To address this issue, we propose a generic and lightweight controllable knowledge re-injection module, which utilizes the sophisticated reasoning ability of LLMs to control the VPG to conditionally extract instruction-specific visual information and re-inject it into the LLM. Further, we introduce an annotation-free cross-attention guided counterfactual image training strategy to methodically learn the proposed module by collaborating a cascade of foundation models. Enhanced by the proposed module and training strategy, we present Cheetor, a Transformer-based MLLM that can effectively handle a wide variety of interleaved vision-language instructions and achieves state-of-the-art zero-shot performance across all tasks of I4, without high-quality multimodal instruction tuning data. Cheetor also exhibits competitive performance compared with state-of-the-art instruction tuned models on MME benchmark.

Large language models (LLMs) are typically trained on general source data for various domains, but a recent surge in domain-specific LLMs has shown their potential to outperform general-purpose models in domain-specific tasks (e.g., biomedicine). Although domain-specific pre-training enhances efficiency and leads to smaller models, the computational costs of training these LLMs remain high, posing budgeting challenges. We introduce MediSwift, a suite of biomedical LMs that leverage sparse pre-training on domain-specific biomedical text data. By inducing up to 75% weight sparsity during the pre-training phase, MediSwift achieves a 2-2.5x reduction in training FLOPs. Notably, all sparse pre-training was performed on the Cerebras CS-2 system, which is specifically designed to realize the acceleration benefits from unstructured weight sparsity, thereby significantly enhancing the efficiency of the MediSwift models. Through subsequent dense fine-tuning and strategic soft prompting, MediSwift models outperform existing LLMs up to 7B parameters on biomedical tasks, setting new benchmarks w.r.t efficiency-accuracy on tasks such as PubMedQA. Our results show that sparse pre-training, along with dense fine-tuning and soft prompting, offers an effective method for creating high-performing, computationally efficient models in specialized domains.

Intelligent agents stand out as a potential path toward artificial general intelligence (AGI). Thus, researchers have dedicated significant effort to diverse implementations for them. Benefiting from recent progress in large language models (LLMs), LLM-based agents that use universal natural language as an interface exhibit robust generalization capabilities across various applications -- from serving as autonomous general-purpose task assistants to applications in coding, social, and economic domains, LLM-based agents offer extensive exploration opportunities. This paper surveys current research to provide an in-depth overview of LLM-based intelligent agents within single-agent and multi-agent systems. It covers their definitions, research frameworks, and foundational components such as their composition, cognitive and planning methods, tool utilization, and responses to environmental feedback. We also delve into the mechanisms of deploying LLM-based agents in multi-agent systems, including multi-role collaboration, message passing, and strategies to alleviate communication issues between agents. The discussions also shed light on popular datasets and application scenarios. We conclude by envisioning prospects for LLM-based agents, considering the evolving landscape of AI and natural language processing.

Large language model (LLM)-based embedding models, benefiting from large scale pre-training and post-training, have begun to surpass BERT and T5-based models on general-purpose text embedding tasks such as document retrieval. However, a fundamental limitation of LLM embeddings lies in the unidirectional attention used during autoregressive pre-training, which misaligns with the bidirectional nature of text embedding tasks. To this end, We propose adopting diffusion language models for text embeddings, motivated by their inherent bidirectional architecture and recent success in matching or surpassing LLMs especially on reasoning tasks. We present the first systematic study of the diffusion language embedding model, which outperforms the LLM-based embedding model by 20% on long-document retrieval, 8% on reasoning-intensive retrieval, 2% on instruction-following retrieval, and achieve competitive performance on traditional text embedding benchmarks. Our analysis verifies that bidirectional attention is crucial for encoding global context in long and complex text.

Hallucination, a phenomenon where large language models (LLMs) produce output that is factually incorrect or unrelated to the input, is a major challenge for LLM applications that require accuracy and dependability. In this paper, we introduce a reliable and high-speed production system aimed at detecting and rectifying the hallucination issue within LLMs. Our system encompasses named entity recognition (NER), natural language inference (NLI), span-based detection (SBD), and an intricate decision tree-based process to reliably detect a wide range of hallucinations in LLM responses. Furthermore, we have crafted a rewriting mechanism that maintains an optimal mix of precision, response time, and cost-effectiveness. We detail the core elements of our framework and underscore the paramount challenges tied to response time, availability, and performance metrics, which are crucial for real-world deployment of these technologies. Our extensive evaluation, utilizing offline data and live production traffic, confirms the efficacy of our proposed framework and service.

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using 277 billion words of mixed clinical and English text with a GPT-3 architecture of 20 billion parameters. GatorTronGPT improves biomedical natural language processing for medical research. Synthetic NLP models trained using GatorTronGPT generated text outperform NLP models trained using real-world clinical text. Physicians Turing test using 1 (worst) to 9 (best) scale shows that there is no significant difference in linguistic readability (p = 0.22; 6.57 of GatorTronGPT compared with 6.93 of human) and clinical relevance (p = 0.91; 7.0 of GatorTronGPT compared with 6.97 of human) and that physicians cannot differentiate them (p < 0.001). This study provides insights on the opportunities and challenges of LLMs for medical research and healthcare.

Tokenization efficiency plays a critical role in the performance and cost of large language models (LLMs), yet most models rely on static tokenizers optimized for general-purpose corpora. These tokenizers' fixed vocabularies often fail to adapt to domain- or language-specific inputs, leading to longer token sequences and higher computational costs. We introduce zip2zip, a framework that enables LLMs to dynamically adjust token vocabulary at inference time, allowing for fewer generated tokens and thus faster inference. zip2zip consists of three key components: (1) a tokenizer based on Lempel-Ziv-Welch (LZW) compression that incrementally compresses tokens into reusable "hypertokens" on the fly; (2) an embedding layer that computes embeddings for newly formed hypertokens at runtime; and (3) a causal language modeling variant that trains the model to operate on hypertokenized, compressed sequences. We show that an existing LLM can be zip2zip-fied in 10 GPU-hours via parameter-efficient finetuning. The resulting zip2zip LLMs effectively learn to use hypertokens at inference time, reducing input and output sequence length by 20-60\%, with significant improvements in inference latency.

Supervised fine-tuning (SFT) plays a critical role for pretrained large language models (LLMs), notably enhancing their capacity to acquire domain-specific knowledge while preserving or potentially augmenting their general-purpose capabilities. However, the efficacy of SFT hinges on data quality as well as data volume, otherwise it may result in limited performance gains or even degradation relative to the associated baselines. To mitigate such reliance, we suggest categorizing tokens within each corpus into two parts -- positive and negative tokens -- based on whether they are useful to improve model performance. Positive tokens can be trained in common ways, whereas negative tokens, which may lack essential semantics or be misleading, should be explicitly forgotten. Overall, the token categorization facilitate the model to learn less informative message, and the forgetting process shapes a knowledge boundary to guide the model on what information to learn more precisely. We conduct experiments on well-established benchmarks, finding that this forgetting mechanism not only improves overall model performance and also facilitate more diverse model responses.

Recently, Large Language Models (LLMs) have showcased remarkable capabilities in natural language understanding. While demonstrating proficiency in everyday conversations and question-answering situations, these models frequently struggle in domains that require precision, such as medical applications, due to their lack of domain-specific knowledge. In this paper, we describe the procedure for building a powerful, open-source language model specifically designed for medicine applications, termed as PMC-LLaMA. Our contributions are threefold: (i) we systematically investigate the process of adapting a general-purpose foundation language model towards medical domain, this involves data-centric knowledge injection through the integration of 4.8M biomedical academic papers and 30K medical textbooks, as well as comprehensive fine-tuning for alignment with domain-specific instructions; (ii) we contribute a large-scale, comprehensive dataset for instruction tuning. This dataset encompasses medical question-answering (QA), rationale for reasoning, and conversational dialogues, comprising a total of 202M tokens; (iii) we conduct thorough ablation studies to demonstrate the effectiveness of each proposed component. While evaluating on various public medical question-answering benchmarks, our lightweight PMCLLaMA, which consists of only 13 billion parameters, exhibits superior performance, even surpassing ChatGPT. All models, codes, datasets can be found in https://github.com/chaoyi-wu/PMC-LLaMA.

Large-scale multilingual machine translation systems have demonstrated remarkable ability to translate directly between numerous languages, making them increasingly appealing for real-world applications. However, when deployed in the wild, these models may generate hallucinated translations which have the potential to severely undermine user trust and raise safety concerns. Existing research on hallucinations has primarily focused on small bilingual models trained on high-resource languages, leaving a gap in our understanding of hallucinations in massively multilingual models across diverse translation scenarios. In this work, we fill this gap by conducting a comprehensive analysis on both the M2M family of conventional neural machine translation models and ChatGPT, a general-purpose large language model~(LLM) that can be prompted for translation. Our investigation covers a broad spectrum of conditions, spanning over 100 translation directions across various resource levels and going beyond English-centric language pairs. We provide key insights regarding the prevalence, properties, and mitigation of hallucinations, paving the way towards more responsible and reliable machine translation systems.

Since the introduction of the Model Context Protocol (MCP), the number of available tools for Large Language Models (LLMs) has increased significantly. These task-specific tool sets offer an alternative to general-purpose tools such as web browsers, while being easier to develop and maintain than GUIs. However, current general-purpose agents predominantly rely on web browsers for interacting with the environment. Here, we introduce TheMCPCompany, a benchmark for evaluating tool-calling agents on tasks that involve interacting with various real-world services. We use the REST APIs of these services to create MCP servers, which include over 18,000 tools. We also provide manually annotated ground-truth tools for each task. In our experiments, we use the ground truth tools to show the potential of tool-calling agents for both improving performance and reducing costs assuming perfect tool retrieval. Next, we explore agent performance using tool retrieval to study the real-world practicality of tool-based agents. While all models with tool retrieval perform similarly or better than browser-based agents, smaller models cannot take full advantage of the available tools through retrieval. On the other hand, GPT-5's performance with tool retrieval is very close to its performance with ground-truth tools. Overall, our work shows that the most advanced reasoning models are effective at discovering tools in simpler environments, but seriously struggle with navigating complex enterprise environments. TheMCPCompany reveals that navigating tens of thousands of tools and combining them in non-trivial ways to solve complex problems is still a challenging task for current models and requires both better reasoning and better retrieval models.

Generating realistic human motion from given action descriptions has experienced significant advancements because of the emerging requirement of digital humans. While recent works have achieved impressive results in generating motion directly from textual action descriptions, they often support only a single modality of the control signal, which limits their application in the real digital human industry. This paper presents a Motion General-Purpose generaTor (MotionGPT) that can use multimodal control signals, e.g., text and single-frame poses, for generating consecutive human motions by treating multimodal signals as special input tokens in large language models (LLMs). Specifically, we first quantize multimodal control signals into discrete codes and then formulate them in a unified prompt instruction to ask the LLMs to generate the motion answer. Our MotionGPT demonstrates a unified human motion generation model with multimodal control signals by tuning a mere 0.4% of LLM parameters. To the best of our knowledge, MotionGPT is the first method to generate human motion by multimodal control signals, which we hope can shed light on this new direction. Codes shall be released upon acceptance.

A vision model with general-purpose object-level 3D understanding should be capable of inferring both 2D (e.g., class name and bounding box) and 3D information (e.g., 3D location and 3D viewpoint) for arbitrary rigid objects in natural images. This is a challenging task, as it involves inferring 3D information from 2D signals and most importantly, generalizing to rigid objects from unseen categories. However, existing datasets with object-level 3D annotations are often limited by the number of categories or the quality of annotations. Models developed on these datasets become specialists for certain categories or domains, and fail to generalize. In this work, we present ImageNet3D, a large dataset for general-purpose object-level 3D understanding. ImageNet3D augments 200 categories from the ImageNet dataset with 2D bounding box, 3D pose, 3D location annotations, and image captions interleaved with 3D information. With the new annotations available in ImageNet3D, we could (i) analyze the object-level 3D awareness of visual foundation models, and (ii) study and develop general-purpose models that infer both 2D and 3D information for arbitrary rigid objects in natural images, and (iii) integrate unified 3D models with large language models for 3D-related reasoning.. We consider two new tasks, probing of object-level 3D awareness and open vocabulary pose estimation, besides standard classification and pose estimation. Experimental results on ImageNet3D demonstrate the potential of our dataset in building vision models with stronger general-purpose object-level 3D understanding.

Proteins, as essential biomolecules, play a central role in biological processes, including metabolic reactions and DNA replication. Accurate prediction of their properties and functions is crucial in biological applications. Recent development of protein language models (pLMs) with supervised fine tuning provides a promising solution to this problem. However, the fine-tuned model is tailored for particular downstream prediction task, and achieving general-purpose protein understanding remains a challenge. In this paper, we introduce Structure-Enhanced Protein Instruction Tuning (SEPIT) framework to bridge this gap. Our approach integrates a noval structure-aware module into pLMs to inform them with structural knowledge, and then connects these enhanced pLMs to large language models (LLMs) to generate understanding of proteins. In this framework, we propose a novel two-stage instruction tuning pipeline that first establishes a basic understanding of proteins through caption-based instructions and then refines this understanding using a mixture of experts (MoEs) to learn more complex properties and functional information with the same amount of activated parameters. Moreover, we construct the largest and most comprehensive protein instruction dataset to date, which allows us to train and evaluate the general-purpose protein understanding model. Extensive experimental results on open-ended generation and closed-set answer tasks demonstrate the superior performance of SEPIT over both closed-source general LLMs and open-source LLMs trained with protein knowledge.

It has long been established that predictive models can be transformed into lossless compressors and vice versa. Incidentally, in recent years, the machine learning community has focused on training increasingly large and powerful self-supervised (language) models. Since these large language models exhibit impressive predictive capabilities, they are well-positioned to be strong compressors. In this work, we advocate for viewing the prediction problem through the lens of compression and evaluate the compression capabilities of large (foundation) models. We show that large language models are powerful general-purpose predictors and that the compression viewpoint provides novel insights into scaling laws, tokenization, and in-context learning. For example, Chinchilla 70B, while trained primarily on text, compresses ImageNet patches to 43.4% and LibriSpeech samples to 16.4% of their raw size, beating domain-specific compressors like PNG (58.5%) or FLAC (30.3%), respectively. Finally, we show that the prediction-compression equivalence allows us to use any compressor (like gzip) to build a conditional generative model.

Large language models (LLMs) have emerged as powerful general-purpose interfaces for many machine learning problems. Recent work has adapted LLMs to generative visual tasks like image captioning, visual question answering, and visual chat, using a relatively small amount of instruction-tuning data. In this paper, we explore whether modern LLMs can also be adapted to classifying an image into a set of categories. First, we evaluate multimodal LLMs that are tuned for generative tasks on zero-shot image classification and find that their performance is far below that of specialized models like CLIP. We then propose an approach for light fine-tuning of LLMs using the same contrastive image-caption matching objective as CLIP. Our results show that LLMs can, indeed, achieve good image classification performance when adapted this way. Our approach beats state-of-the-art mLLMs by 13% and slightly outperforms contrastive learning with a custom text model, while also retaining the LLM's generative abilities. LLM initialization appears to particularly help classification in domains under-represented in the visual pre-training data.

Large language models are increasingly capable of handling long-context inputs, but the memory overhead of key-value (KV) cache remains a major bottleneck for general-purpose deployment. While various compression strategies have been explored, sequence-level compression, which drops the full KV caches for certain tokens, is particularly challenging as it can lead to the loss of important contextual information. To address this, we introduce UniGist, a sequence-level long-context compression framework that efficiently preserves context information by replacing raw tokens with special compression tokens (gists) in a fine-grained manner. We adopt a chunk-free training strategy and design an efficient kernel with a gist shift trick, enabling optimized GPU training. Our scheme also supports flexible inference by allowing the actual removal of compressed tokens, resulting in real-time memory savings. Experiments across multiple long-context tasks demonstrate that UniGist significantly improves compression quality, with especially strong performance in detail-recalling tasks and long-range dependency modeling.

Multimodal generative models require a unified approach to handle both discrete data (e.g., text and code) and continuous data (e.g., image, audio, video). In this work, we propose Latent Language Modeling (LatentLM), which seamlessly integrates continuous and discrete data using causal Transformers. Specifically, we employ a variational autoencoder (VAE) to represent continuous data as latent vectors and introduce next-token diffusion for autoregressive generation of these vectors. Additionally, we develop sigma-VAE to address the challenges of variance collapse, which is crucial for autoregressive modeling. Extensive experiments demonstrate the effectiveness of LatentLM across various modalities. In image generation, LatentLM surpasses Diffusion Transformers in both performance and scalability. When integrated into multimodal large language models, LatentLM provides a general-purpose interface that unifies multimodal generation and understanding. Experimental results show that LatentLM achieves favorable performance compared to Transfusion and vector quantized models in the setting of scaling up training tokens. In text-to-speech synthesis, LatentLM outperforms the state-of-the-art VALL-E 2 model in speaker similarity and robustness, while requiring 10x fewer decoding steps. The results establish LatentLM as a highly effective and scalable approach to advance large multimodal models.

Significant focus has been placed on integrating large language models (LLMs) with various tools in developing general-purpose agents. This poses a challenge to LLMs' tool-use capabilities. However, there are evident gaps between existing tool-use evaluations and real-world scenarios. Current evaluations often use AI-generated queries, single-step tasks, dummy tools, and text-only interactions, failing to reveal the agents' real-world problem-solving abilities effectively. To address this, we propose GTA, a benchmark for General Tool Agents, featuring three main aspects: (i) Real user queries: human-written queries with simple real-world objectives but implicit tool-use, requiring the LLM to reason the suitable tools and plan the solution steps. (ii) Real deployed tools: an evaluation platform equipped with tools across perception, operation, logic, and creativity categories to evaluate the agents' actual task execution performance. (iii) Real multimodal inputs: authentic image files, such as spatial scenes, web page screenshots, tables, code snippets, and printed/handwritten materials, used as the query contexts to align with real-world scenarios closely. We design 229 real-world tasks and executable tool chains to evaluate mainstream LLMs. Our findings show that real-world user queries are challenging for existing LLMs, with GPT-4 completing less than 50% of the tasks and most LLMs achieving below 25%. This evaluation reveals the bottlenecks in the tool-use capabilities of current LLMs in real-world scenarios, which provides future direction for advancing general-purpose tool agents. The code and dataset are available at https://github.com/open-compass/GTA.

Recent advances in Video Large Language Models (Video-LLMs) have demonstrated their great potential in general-purpose video understanding. To verify the significance of these models, a number of benchmarks have been proposed to diagnose their capabilities in different scenarios. However, existing benchmarks merely evaluate models through video-level question-answering, lacking fine-grained event-level assessment and task diversity. To fill this gap, we introduce E.T. Bench (Event-Level & Time-Sensitive Video Understanding Benchmark), a large-scale and high-quality benchmark for open-ended event-level video understanding. Categorized within a 3-level task taxonomy, E.T. Bench encompasses 7.3K samples under 12 tasks with 7K videos (251.4h total length) under 8 domains, providing comprehensive evaluations. We extensively evaluated 8 Image-LLMs and 12 Video-LLMs on our benchmark, and the results reveal that state-of-the-art models for coarse-level (video-level) understanding struggle to solve our fine-grained tasks, e.g., grounding event-of-interests within videos, largely due to the short video context length, improper time representations, and lack of multi-event training data. Focusing on these issues, we further propose a strong baseline model, E.T. Chat, together with an instruction-tuning dataset E.T. Instruct 164K tailored for fine-grained event-level understanding. Our simple but effective solution demonstrates superior performance in multiple scenarios.

The integration of large language models (LLMs) with vision-language (VL) tasks has been a transformative development in the realm of artificial intelligence, highlighting the potential of LLMs as a versatile general-purpose chatbot. However, the current trend in this evolution focuses on the integration of vision and language to create models that can operate in more diverse and real-world contexts. We present a novel approach, termed Bottleneck Adapter, specifically crafted for enhancing the multimodal functionalities of these complex models, enabling joint optimization of the entire multimodal LLM framework through a process known as Multimodal Model Tuning (MMT). Our approach utilizes lightweight adapters to connect the image encoder and LLM without the need for large, complex neural networks. Unlike the conventional modular training schemes, our approach adopts an end-to-end optimization regime, which, when combined with the adapters, facilitates the joint optimization using a significantly smaller parameter set. Our method exhibits robust performance with 90.12\% accuracy, outperforming both human-level performance (88.4\%) and LaVIN-7B (89.41\%).

In recent times Large Language Models have exhibited tremendous capabilities, especially in the areas of mathematics, code generation and general-purpose reasoning. However for specialized domains especially in applications that require parsing and analyzing large chunks of numeric or tabular data even state-of-the-art (SOTA) models struggle. In this paper, we introduce a new approach to solving domain-specific tabular data analysis tasks by presenting a unique RAG workflow that mitigates the scalability issues of existing tabular LLM solutions. Specifically, we present Tabular Embedding Model (TEM), a novel approach to fine-tune embedding models for tabular Retrieval-Augmentation Generation (RAG) applications. Embedding models form a crucial component in the RAG workflow and even current SOTA embedding models struggle as they are predominantly trained on textual datasets and thus underperform in scenarios involving complex tabular data. The evaluation results showcase that our approach not only outperforms current SOTA embedding models in this domain but also does so with a notably smaller and more efficient model structure.

The ability to summarize long documents succinctly is increasingly important in daily life due to information overload, yet there is a notable lack of such summaries for Spanish documents in general, and in the legal domain in particular. In this work, we present BOE-XSUM, a curated dataset comprising 3,648 concise, plain-language summaries of documents sourced from Spain's ``Bolet\'{\i}n Oficial del Estado'' (BOE), the State Official Gazette. Each entry in the dataset includes a short summary, the original text, and its document type label. We evaluate the performance of medium-sized large language models (LLMs) fine-tuned on BOE-XSUM, comparing them to general-purpose generative models in a zero-shot setting. Results show that fine-tuned models significantly outperform their non-specialized counterparts. Notably, the best-performing model -- BERTIN GPT-J 6B (32-bit precision) -- achieves a 24\% performance gain over the top zero-shot model, DeepSeek-R1 (accuracies of 41.6\% vs.\ 33.5\%).

Multi-modal Large Language Models (MLLMs) have recently exhibited impressive general-purpose capabilities by leveraging vision foundation models to encode the core concepts of images into representations. These are then combined with instructions and processed by the language model to generate high-quality responses. Despite significant progress in enhancing the language component, challenges persist in optimally fusing visual encodings within the language model for task-specific adaptability. Recent research has focused on improving this fusion through modality adaptation modules but at the cost of significantly increased model complexity and training data needs. In this paper, we propose EMMA (Efficient Multi-Modal Adaptation), a lightweight cross-modality module designed to efficiently fuse visual and textual encodings, generating instruction-aware visual representations for the language model. Our key contributions include: (1) an efficient early fusion mechanism that integrates vision and language representations with minimal added parameters (less than 0.2% increase in model size), (2) an in-depth interpretability analysis that sheds light on the internal mechanisms of the proposed method; (3) comprehensive experiments that demonstrate notable improvements on both specialized and general benchmarks for MLLMs. Empirical results show that EMMA boosts performance across multiple tasks by up to 9.3% while significantly improving robustness against hallucinations. Our code is available at https://github.com/SaraGhazanfari/EMMA

Evaluating large language models (LLMs) as general-purpose agents is essential for understanding their capabilities and facilitating their integration into practical applications. However, the evaluation process presents substantial challenges. A primary obstacle is the benchmarking of agent performance across diverse scenarios within a unified framework, especially in maintaining partially-observable environments and ensuring multi-round interactions. Moreover, current evaluation frameworks mostly focus on the final success rate, revealing few insights during the process and failing to provide a deep understanding of the model abilities. To address these challenges, we introduce AgentBoard, a pioneering comprehensive benchmark and accompanied open-source evaluation framework tailored to analytical evaluation of LLM agents. AgentBoard offers a fine-grained progress rate metric that captures incremental advancements as well as a comprehensive evaluation toolkit that features easy assessment of agents for multi-faceted analysis through interactive visualization. This not only sheds light on the capabilities and limitations of LLM agents but also propels the interpretability of their performance to the forefront. Ultimately, AgentBoard serves as a significant step towards demystifying agent behaviors and accelerating the development of stronger LLM agents.

Multimodal large language models (MLLMs) have demonstrated strong general-purpose capabilities in open-world visual comprehension. However, most existing MLLMs primarily focus on holistic, scene-level understanding, often overlooking the need for fine-grained, object-centric reasoning. In this paper, we present PixelRefer, a unified region-level MLLM framework that enables advanced fine-grained understanding over user-specified regions across both images and videos. Motivated by the observation that LLM attention predominantly focuses on object-level tokens, we propose a Scale-Adaptive Object Tokenizer (SAOT) to generate compact and semantically rich object representations from free-form regions. Our analysis reveals that global visual tokens contribute mainly in early LLM layers, inspiring the design of PixelRefer-Lite, an efficient variant that employs an Object-Centric Infusion module to pre-fuse global context into object tokens. This yields a lightweight Object-Only Framework that substantially reduces computational cost while maintaining high semantic fidelity. To facilitate fine-grained instruction tuning, we curate PixelRefer-2.2M, a high-quality object-centric instruction dataset. Extensive experiments across a range of benchmarks validate that PixelRefer achieves leading performance with fewer training samples, while PixelRefer-Lite offers competitive accuracy with notable gains in efficiency.

The increasing complexity and high costs associated with modern processor design have led to a surge in demand for processor design automation. Instruction-tuned large language models (LLMs) have demonstrated remarkable performance in automatically generating code for general-purpose programming languages like Python. However, these methods fail on hardware description languages (HDLs) like Verilog due to the scarcity of high-quality instruction tuning data, as even advanced LLMs like GPT-3.5 exhibit limited performance on Verilog generation. Regarding this issue, we observe that (1) Verilog code collected from the real world has higher quality than those generated by LLMs. (2) LLMs like GPT-3.5 excel in summarizing Verilog code rather than generating it. Based on these observations, this paper introduces CodeV, a series of open-source instruction-tuned Verilog generation LLMs. Instead of generating descriptions first and then getting the corresponding code from advanced LLMs, we prompt the LLM with Verilog code and let the LLM generate the corresponding natural language description by multi-level summarization. Experimental results show that CodeV relatively surpasses the previous open-source SOTA by 14.4% (BetterV in VerilogEval) and 11.3% (RTLCoder in RTLLM) respectively, and also relatively outperforms previous commercial SOTA GPT-4 by 22.1% in VerilogEval.

Multimodal large language models (MLLMs) have recently achieved impressive general-purpose vision-language capabilities through visual instruction tuning. However, current MLLMs primarily focus on image-level or box-level understanding, falling short of achieving fine-grained vision-language alignment at the pixel level. Besides, the lack of mask-based instruction data limits their advancements. In this paper, we propose Osprey, a mask-text instruction tuning approach, to extend MLLMs by incorporating fine-grained mask regions into language instruction, aiming at achieving pixel-wise visual understanding. To achieve this goal, we first meticulously curate a mask-based region-text dataset with 724K samples, and then design a vision-language model by injecting pixel-level representation into LLM. Especially, Osprey adopts a convolutional CLIP backbone as the vision encoder and employs a mask-aware visual extractor to extract precise visual mask features from high resolution input. Experimental results demonstrate Osprey's superiority in various region understanding tasks, showcasing its new capability for pixel-level instruction tuning. In particular, Osprey can be integrated with Segment Anything Model (SAM) seamlessly to obtain multi-granularity semantics. The source code, dataset and demo can be found at https://github.com/CircleRadon/Osprey.

While multimodal large language models (MLLMs) have demonstrated extraordinary vision-language understanding capabilities and shown potential to serve as general-purpose assistants, their abilities to solve instance-level visual-language problems beyond a single image warrant further exploration. In order to assess these unproven abilities of MLLMs, this paper proposes a new visual grounding task called multi-context visual grounding, which aims to localize instances of interest across multiple images based on open-ended text prompts. To facilitate this research, we meticulously construct a new dataset MC-Bench for benchmarking the visual grounding capabilities of MLLMs. MC-Bench features 2K high-quality and manually annotated samples, consisting of instance-level labeled image pairs and corresponding text prompts that indicate the target instances in the images. In total, there are three distinct styles of text prompts, covering 20 practical skills. We benchmark over 20 state-of-the-art MLLMs and foundation models with potential multi-context visual grounding capabilities. Our evaluation reveals a non-trivial performance gap between existing MLLMs and humans across all metrics. We also observe that existing MLLMs typically outperform foundation models without LLMs only on image-level metrics, and the specialist MLLMs trained on single images often struggle to generalize to multi-image scenarios. Moreover, a simple stepwise baseline integrating advanced MLLM and a detector can significantly surpass prior end-to-end MLLMs. We hope our MC-Bench and empirical findings can encourage the research community to further explore and enhance the untapped potentials of MLLMs in instance-level tasks, particularly in multi-image contexts. Project page: https://xuyunqiu.github.io/MC-Bench/.

Large Language Models work quite well with general-purpose data and many tasks in Natural Language Processing. However, they show several limitations when used for a task such as domain-specific abstractive text summarization. This paper identifies three of those limitations as research problems in the context of abstractive text summarization: 1) Quadratic complexity of transformer-based models with respect to the input text length; 2) Model Hallucination, which is a model's ability to generate factually incorrect text; and 3) Domain Shift, which happens when the distribution of the model's training and test corpus is not the same. Along with a discussion of the open research questions, this paper also provides an assessment of existing state-of-the-art techniques relevant to domain-specific text summarization to address the research gaps.

Large Language Models (LLMs) exhibit strong general-purpose reasoning abilities but lack access to wireless environment information due to the absence of native sensory input and domain-specific priors. Previous attempts to apply LLMs in wireless systems either depend on retraining with network-specific data, which compromises language generalization, or rely on manually scripted interfaces, which hinder scalability. To overcome these limitations, we propose a Model Context Protocol (MCP)-based Internet of Experts (IoX) framework that equips LLMs with wireless environment-aware reasoning capabilities. The framework incorporates a set of lightweight expert models, each trained to solve a specific deterministic task in wireless communications, such as detecting a specific wireless attribute, e.g., line-of-sight propagation, Doppler effects, or fading conditions. Through MCP, the LLM can selectively query and interpret expert outputs at inference time, without modifying its own parameters. This architecture enables modular, extensible, and interpretable reasoning over wireless contexts. Evaluated across multiple mainstream LLMs, the proposed wireless environment-aware LLM agents achieve 40%-50% improvements in classification tasks over LLM-only baselines. More broadly, the MCP-based design offers a viable paradigm for future LLMs to inherit structured wireless network management capabilities.

Speech encompasses a wealth of information, including but not limited to content, paralinguistic, and environmental information. This comprehensive nature of speech significantly impacts communication and is crucial for human-computer interaction. Chat-Oriented Large Language Models (LLMs), known for their general-purpose assistance capabilities, have evolved to handle multi-modal inputs, including speech. Although these models can be adept at recognizing and analyzing speech, they often fall short of generating appropriate responses. We argue that this is due to the lack of principles on task definition and model development, which requires open-source datasets and metrics suitable for model evaluation. To bridge the gap, we present SD-Eval, a benchmark dataset aimed at multidimensional evaluation of spoken dialogue understanding and generation. SD-Eval focuses on paralinguistic and environmental information and includes 7,303 utterances, amounting to 8.76 hours of speech data. The data is aggregated from eight public datasets, representing four perspectives: emotion, accent, age, and background sound. To assess the SD-Eval benchmark dataset, we implement three different models and construct a training set following a similar process as SD-Eval. The training set contains 1,052.72 hours of speech data and 724.4k utterances. We also conduct a comprehensive evaluation using objective evaluation methods (e.g. BLEU and ROUGE), subjective evaluations and LLM-based metrics for the generated responses. Models conditioned with paralinguistic and environmental information outperform their counterparts in both objective and subjective measures. Moreover, experiments demonstrate LLM-based metrics show a higher correlation with human evaluation compared to traditional metrics. We open-source SD-Eval at https://github.com/amphionspace/SD-Eval.

The advancement of general-purpose artificial intelligence relies on large language models (LLMs) that excel across a wide range of tasks, from structured reasoning to creative generation. However, post-training methods like Supervised Fine-Tuning (SFT) often struggle with generalization, favoring memorization over transferable learning. In this work, we introduce Omni-Thinker, a unified reinforcement learning (RL) framework that enhances LLM performance across diverse tasks by combining rule-based verifiable rewards with generative preference signals via LLM-as-a-Judge evaluations. Our approach enables consistent optimization across task types and scales RL-based training to subjective domains. We further investigate training strategies, demonstrating that a curriculum-based progression that orders tasks from structured to open-ended improves performance and reduces forgetting. Experimental results across four domains reveal that curriculum learning improves performance by 5.2% over joint training and 9.1% over model merging. These results highlight the importance of task-aware sampling and hybrid supervision in scaling RL-based post-training for general-purpose LLMs.

Multimodal large language models (MLLMs) like LLaVA and GPT-4(V) enable general-purpose conversations about images with the language modality. As off-the-shelf MLLMs may have limited capabilities on images from domains like dermatology and agriculture, they must be fine-tuned to unlock domain-specific applications. The prevalent architecture of current open-source MLLMs comprises two major modules: an image-language (cross-modal) projection network and a large language model. It is desirable to understand the roles of these two modules in modeling domain-specific visual attributes to inform the design of future models and streamline the interpretability efforts on the current models. To this end, via experiments on 4 datasets and under 2 fine-tuning settings, we find that as the MLLM is fine-tuned, it indeed gains domain-specific visual capabilities, but the updates do not lead to the projection extracting relevant domain-specific visual attributes. Our results indicate that the domain-specific visual attributes are modeled by the LLM, even when only the projection is fine-tuned. Through this study, we offer a potential reinterpretation of the role of cross-modal projections in MLLM architectures. Projection webpage: https://claws-lab.github.io/projection-in-MLLMs/

Large Language Models (LLMs) have shown impressive versatility as general purpose models. However, their broad applicability comes at a high-cost computational overhead, particularly in auto-regressive decoding where each step requires a forward pass. In domain-specific settings, general-purpose capabilities are unnecessary and can be exchanged for efficiency. In this work, we take a novel perspective on domain adaptation, reducing latency and computational costs by adapting the vocabulary to focused domains of interest. We introduce AdaptiVocab, an end-to-end approach for vocabulary adaptation, designed to enhance LLM efficiency in low-resource domains. AdaptiVocab can be applied to any tokenizer and architecture, modifying the vocabulary by replacing tokens with domain-specific n-gram-based tokens, thereby reducing the number of tokens required for both input processing and output generation. AdaptiVocab initializes new n-token embeddings using an exponentially weighted combination of existing embeddings and employs a lightweight fine-tuning phase that can be efficiently performed on a single GPU. We evaluate two 7B LLMs across three niche domains, assessing efficiency, generation quality, and end-task performance. Our results show that AdaptiVocab reduces token usage by over 25% without compromising performance

Large language models (LLMs) have shown impressive performance on general-purpose tasks, yet adapting them to specific domains remains challenging due to the scarcity of high-quality domain data. Existing data synthesis tools often struggle to extract reliable fine-tuning data from heterogeneous documents effectively. To address this limitation, we propose Easy Dataset, a unified framework for synthesizing fine-tuning data from unstructured documents via an intuitive graphical user interface (GUI). Specifically, Easy Dataset allows users to easily configure text extraction models and chunking strategies to transform raw documents into coherent text chunks. It then leverages a persona-driven prompting approach to generate diverse question-answer pairs using public-available LLMs. Throughout the pipeline, a human-in-the-loop visual interface facilitates the review and refinement of intermediate outputs to ensure data quality. Experiments on a financial question-answering task show that fine-tuning LLMs on the synthesized dataset significantly improves domain-specific performance while preserving general knowledge. The source code and installable package are available at https://github.com/ConardLi/easy-dataset and have garnered over 9,000 GitHub stars.

Large language models like GPT-4 exhibit emergent capabilities across general-purpose tasks, such as basic arithmetic, when trained on extensive text data, even though these tasks are not explicitly encoded by the unsupervised, next-token prediction objective. This study investigates how small transformers, trained from random initialization, can efficiently learn arithmetic operations such as addition, multiplication, and elementary functions like square root, using the next-token prediction objective. We first demonstrate that conventional training data is not the most effective for arithmetic learning, and simple formatting changes can significantly improve accuracy. This leads to sharp phase transitions as a function of training data scale, which, in some cases, can be explained through connections to low-rank matrix completion. Building on prior work, we then train on chain-of-thought style data that includes intermediate step results. Even in the complete absence of pretraining, this approach significantly and simultaneously improves accuracy, sample complexity, and convergence speed. We also study the interplay between arithmetic and text data during training and examine the effects of few-shot prompting, pretraining, and model scale. Additionally, we discuss length generalization challenges. Our work highlights the importance of high-quality, instructive data that considers the particular characteristics of the next-word prediction objective for rapidly eliciting arithmetic capabilities.

Large Language Models (LLMs) have demonstrated remarkable success as general-purpose task solvers across various fields, including NLP, healthcare, finance, and law. However, their capabilities remain limited when addressing domain-specific problems, particularly in downstream NLP tasks. Research has shown that models fine-tuned on instruction-based downstream NLP datasets outperform those that are not fine-tuned. While most efforts in this area have primarily focused on resource-rich languages like English and broad domains, little attention has been given to multilingual settings and specific domains. To address this gap, this study focuses on developing a specialized LLM, LlamaLens, for analyzing news and social media content in a multilingual context. To the best of our knowledge, this is the first attempt to tackle both domain specificity and multilinguality, with a particular focus on news and social media. Our experimental setup includes 19 tasks, represented by 52 datasets covering Arabic, English, and Hindi. We demonstrate that LlamaLens outperforms the current state-of-the-art (SOTA) on 16 testing sets, and achieves comparable performance on 10 sets. We make the models and resources publicly available for the research community.(https://huggingface.co/QCRI)

Large Language Models (LLMs) have shown impressive performance as general purpose agents, but their abilities remain highly dependent on prompts which are hand written with onerous trial-and-error effort. We propose a simple and nonparametric solution to this problem, Automatic Prompt Optimization (APO), which is inspired by numerical gradient descent to automatically improve prompts, assuming access to training data and an LLM API. The algorithm uses minibatches of data to form natural language ``gradients'' that criticize the current prompt. The gradients are then ``propagated'' into the prompt by editing the prompt in the opposite semantic direction of the gradient. These gradient descent steps are guided by a beam search and bandit selection procedure which significantly improves algorithmic efficiency. Preliminary results across three benchmark NLP tasks and the novel problem of LLM jailbreak detection suggest that Automatic Prompt Optimization can outperform prior prompt editing techniques and improve an initial prompt's performance by up to 31\%, by using data to rewrite vague task descriptions into more precise annotation instructions.

Large Language Models (LLMs) have emerged as powerful general-purpose reasoning systems, yet their development remains dominated by English-centric data, architectures, and optimization paradigms. This exclusionary design results in structural under-representation of linguistically diverse regions such as India, where over 20 official languages and 100+ dialects coexist alongside phenomena like code-switching and diglossia. We introduce PARAM-1, a 2.9B parameter decoder-only, text-only language model trained from scratch with an explicit architectural and linguistic focus on Indian diversity. PARAM-1 is trained on a bilingual dataset consisting of only Hindi and English, constructed with a strong focus on fact-rich, high-quality content. It is guided by three core principles: equitable representation of Indic languages through a 25% corpus allocation; tokenization fairness via a SentencePiece tokenizer adapted to Indian morphological structures; and culturally aligned evaluation benchmarks across IndicQA, code-mixed reasoning, and socio-linguistic robustness tasks. By embedding diversity at the pretraining level-rather than deferring it to post-hoc alignment-PARAM-1 offers a design-first blueprint for equitable foundation modeling. Our results demonstrate that it serves as both a competent general-purpose model and a robust baseline for India-centric applications.

Large Language Models (LLMs) such as GPT-3 have emerged as general-purpose language models capable of addressing many natural language generation or understanding tasks. On the task of Machine Translation (MT), multiple works have investigated few-shot prompting mechanisms to elicit better translations from LLMs. However, there has been relatively little investigation on how such translations differ qualitatively from the translations generated by standard Neural Machine Translation (NMT) models. In this work, we investigate these differences in terms of the literalness of translations produced by the two systems. Using literalness measures involving word alignment and monotonicity, we find that translations out of English (E-X) from GPTs tend to be less literal, while exhibiting similar or better scores on MT quality metrics. We demonstrate that this finding is borne out in human evaluations as well. We then show that these differences are especially pronounced when translating sentences that contain idiomatic expressions.

While embeddings from multimodal large language models (LLMs) excel as general-purpose representations, their application to dynamic modalities like audio and video remains underexplored. We introduce WAVE (unified \& versatile audio-visual embeddings), the first LLM-based embedding that creates a unified representation space for text, audio, and video modalities. WAVE employs a novel hierarchical feature fusion strategy and a joint multi-modal, multi-task training approach to enable two key capabilities: any-to-any cross-modal retrieval and the generation of prompt-aware embeddings tailored to user instructions. Experimentally, WAVE sets a new state-of-the-art on the MMEB-v2 video benchmark and achieves superior results in audio and video-to-audio retrieval. Its prompt-aware nature also yields remarkable performance in multimodal question answering, significantly outperforming existing embedding models. Ablation studies validate our joint training strategy, demonstrating improved performance across all modalities. With a newly introduced benchmark for versatile audio-visual learning, WAVE opens up broad possibilities for cross-modal, any-to-any applications. Our code, checkpoints, and data will be released.

Large language models (LLMs) are widely used as general-purpose knowledge sources, but they rely on parametric knowledge, limiting explainability and trustworthiness. In task-oriented dialogue (TOD) systems, this separation is explicit, using an external database structured by an explicit ontology to ensure explainability and controllability. However, building such ontologies requires manual labels or supervised training. We introduce TeQoDO: a Text-to-SQL task-oriented Dialogue Ontology construction method. Here, an LLM autonomously builds a TOD ontology from scratch without supervision using its inherent SQL programming capabilities combined with dialogue theory provided in the prompt. We show that TeQoDO outperforms transfer learning approaches, and its constructed ontology is competitive on a downstream dialogue state tracking task. Ablation studies demonstrate the key role of dialogue theory. TeQoDO also scales to allow construction of much larger ontologies, which we investigate on a Wikipedia and ArXiv dataset. We view this as a step towards broader application of ontologies to increase LLM explainability.

Large language models (LLMs) have rapidly progressed into general-purpose agents capable of solving a broad spectrum of tasks. However, current models remain inefficient at reasoning: they apply fixed inference-time compute regardless of task complexity, often overthinking simple problems while underthinking hard ones. This survey presents a comprehensive review of efficient test-time compute (TTC) strategies, which aim to improve the computational efficiency of LLM reasoning. We introduce a two-tiered taxonomy that distinguishes between L1-controllability, methods that operate under fixed compute budgets, and L2-adaptiveness, methods that dynamically scale inference based on input difficulty or model confidence. We benchmark leading proprietary LLMs across diverse datasets, highlighting critical trade-offs between reasoning performance and token usage. Compared to prior surveys on efficient reasoning, our review emphasizes the practical control, adaptability, and scalability of TTC methods. Finally, we discuss emerging trends such as hybrid thinking models and identify key challenges for future work towards making LLMs more computationally efficient, robust, and responsive to user constraints.

Large Language Models (LLMs) have demonstrated strong capabilities in general-purpose code generation. However, generating the code which is deeply hardware-specific, architecture-aware, and performance-critical, especially for massively parallel GPUs, remains a complex challenge. In this work, we explore the use of LLMs for the automated generation and optimization of CUDA programs, with the goal of producing high-performance GPU kernels that fully exploit the underlying hardware. To address this challenge, we propose a novel framework called Feature Search and Reinforcement (FSR). FSR jointly optimizes compilation and functional correctness, as well as the runtime performance, which are validated through extensive and diverse test cases, and measured by actual kernel execution latency on the target GPU, respectively. This approach enables LLMs not only to generate syntactically and semantically correct CUDA code but also to iteratively refine it for efficiency, tailored to the characteristics of the GPU architecture. We evaluate FSR on representative CUDA kernels, covering AI workloads and computational intensive algorithms. Our results show that LLMs augmented with FSR consistently guarantee correctness rates. Meanwhile, the automatically generated kernels can outperform general human-written code by a factor of up to 179times in execution speeds. These findings highlight the potential of combining LLMs with performance reinforcement to automate GPU programming for hardware-specific, architecture-sensitive, and performance-critical applications.

Large Language Models (LLMs) have garnered significant attention for their impressive general-purpose capabilities. For applications requiring intricate domain knowledge, Retrieval-Augmented Generation (RAG) has shown a distinct advantage in incorporating domain-specific information into LLMs. However, existing RAG research has not fully addressed the challenges of Multiple Choice Question Answering (MCQA) in telecommunications, particularly in terms of retrieval quality and mitigating hallucinations. To tackle these challenges, we propose a novel first token probability guided RAG framework. This framework leverages confidence scores to optimize key hyperparameters, such as chunk number and chunk window size, while dynamically adjusting the context. Our method starts by retrieving the most relevant chunks and generates a single token as the potential answer. The probabilities of all options are then normalized to serve as confidence scores, which guide the dynamic adjustment of the context. By iteratively optimizing the hyperparameters based on these confidence scores, we can continuously improve RAG performance. We conducted experiments to validate the effectiveness of our framework, demonstrating its potential to enhance accuracy in domain-specific MCQA tasks.

While Large Language Models (LLMs) demonstrate exceptional natural language capabilities, general-purpose models lack specialized domain knowledge for effective cybersecurity analysis. In this work, we investigate Domain-Adaptive Continuous Pretraining (DAP) as a methodology for enhancing cybersecurity understanding in pretrained LLMs while preserving general language capabilities. We systematically adapted three decoder-based architectures -- Llama-3.1-8B, DeepSeek-R1-Distill-Qwen-14B, and Llama-3.3-70B-Instruct -- using a curated 126-million-word cybersecurity corpus from standards, academic literature, and various other sources. Our approach employed constrained training parameters and distributed FSDP training to balance domain specialization with knowledge preservation. Evaluation across three cybersecurity benchmarks, namely, CTI-MCQ, CyberMetric, and SecEval, demonstrates consistent improvements post-adaptation. The Llama-3.3-70B-Ins-DAP model achieved state-of-the-art accuracies of 0.718, 0.933, and 0.864, respectively, outperforming specialized models, including Llama-Primus-Base. Notably, competitive performance was achieved using substantially smaller datasets (118.8 million versus 2.77 billion tokens), demonstrating efficient domain specialization viability. We establish that targeted continuous pretraining enables effective cybersecurity domain adaptation with computational feasibility, providing foundations for specialized AI assistants in threat analysis, vulnerability assessment, and security documentation while challenging prevailing assumptions about data requirements for LLM specialization.

We propose a general-purpose approach for improving the ability of Large Language Models (LLMs) to intelligently and adaptively gather information from a user or other external source using the framework of sequential Bayesian experimental design (BED). This enables LLMs to act as effective multi-turn conversational agents and interactively interface with external environments. Our approach, which we call BED-LLM (Bayesian Experimental Design with Large Language Models), is based on iteratively choosing questions or queries that maximize the expected information gain (EIG) about the task of interest given the responses gathered previously. We show how this EIG can be formulated in a principled way using a probabilistic model derived from the LLM's belief distribution and provide detailed insights into key decisions in its construction. Further key to the success of BED-LLM are a number of specific innovations, such as a carefully designed estimator for the EIG, not solely relying on in-context updates for conditioning on previous responses, and a targeted strategy for proposing candidate queries. We find that BED-LLM achieves substantial gains in performance across a wide range of tests based on the 20-questions game and using the LLM to actively infer user preferences, compared to direct prompting of the LLM and other adaptive design strategies.

Few-Shot Relation Extraction (FSRE) remains a challenging task due to the scarcity of annotated data and the limited generalization capabilities of existing models. Although large language models (LLMs) have demonstrated potential in FSRE through in-context learning (ICL), their general-purpose training objectives often result in suboptimal performance for task-specific relation extraction. To overcome these challenges, we propose TKRE (Two-Stage Knowledge-Guided Pre-training for Relation Extraction), a novel framework that synergistically integrates LLMs with traditional relation extraction models, bridging generative and discriminative learning paradigms. TKRE introduces two key innovations: (1) leveraging LLMs to generate explanation-driven knowledge and schema-constrained synthetic data, addressing the issue of data scarcity; and (2) a two-stage pre-training strategy combining Masked Span Language Modeling (MSLM) and Span-Level Contrastive Learning (SCL) to enhance relational reasoning and generalization. Together, these components enable TKRE to effectively tackle FSRE tasks. Comprehensive experiments on benchmark datasets demonstrate the efficacy of TKRE, achieving new state-of-the-art performance in FSRE and underscoring its potential for broader application in low-resource scenarios. \footnote{The code and data are released on https://github.com/UESTC-GQJ/TKRE.

Multimodal Large Language Models (MLLMs) are increasingly deployed in fine-tuning-as-a-service (FTaaS) settings, where user-submitted datasets adapt general-purpose models to downstream tasks. This flexibility, however, introduces serious security risks, as malicious fine-tuning can implant backdoors into MLLMs with minimal effort. In this paper, we observe that backdoor triggers systematically disrupt cross-modal processing by causing abnormal attention concentration on non-semantic regions--a phenomenon we term attention collapse. Based on this insight, we propose Believe Your Eyes (BYE), a data filtering framework that leverages attention entropy patterns as self-supervised signals to identify and filter backdoor samples. BYE operates via a three-stage pipeline: (1) extracting attention maps using the fine-tuned model, (2) computing entropy scores and profiling sensitive layers via bimodal separation, and (3) performing unsupervised clustering to remove suspicious samples. Unlike prior defenses, BYE equires no clean supervision, auxiliary labels, or model modifications. Extensive experiments across various datasets, models, and diverse trigger types validate BYE's effectiveness: it achieves near-zero attack success rates while maintaining clean-task performance, offering a robust and generalizable solution against backdoor threats in MLLMs.

Although Large Language Models (LLMs) have demonstrated remarkable progress, their proficiency in graph-related tasks remains notably limited, hindering the development of truly general-purpose models. Previous attempts, including pretraining graph foundation models or employing supervised fine-tuning, often face challenges such as the scarcity of large-scale, universally represented graph data. We introduce G1, a simple yet effective approach demonstrating that Reinforcement Learning (RL) on synthetic graph-theoretic tasks can significantly scale LLMs' graph reasoning abilities. To enable RL training, we curate Erd\~os, the largest graph reasoning dataset to date comprising 50 diverse graph-theoretic tasks of varying difficulty levels, 100k training data and 5k test data, all drived from real-world graphs. With RL on Erd\~os, G1 obtains substantial improvements in graph reasoning, where our finetuned 3B model even outperforms Qwen2.5-72B-Instruct (24x size). RL-trained models also show strong zero-shot generalization to unseen tasks, domains, and graph encoding schemes, including other graph-theoretic benchmarks as well as real-world node classification and link prediction tasks, without compromising general reasoning abilities. Our findings offer an efficient, scalable path for building strong graph reasoners by finetuning LLMs with RL on graph-theoretic tasks, which combines the strengths of pretrained LLM capabilities with abundant, automatically generated synthetic data, suggesting that LLMs possess graph understanding abilities that RL can elicit successfully.

While large language models (LLMs) have been widely applied to code generation, they struggle with generating entire deep learning projects, which are characterized by complex structures, longer functions, and stronger reliance on domain knowledge than general-purpose code. An open-domain LLM often lacks coherent contextual guidance and domain expertise for specific projects, making it challenging to produce complete code that fully meets user requirements. In this paper, we propose a novel planning-guided code generation method, DLCodeGen, tailored for generating deep learning projects. DLCodeGen predicts a structured solution plan, offering global guidance for LLMs to generate the project. The generated plan is then leveraged to retrieve semantically analogous code samples and subsequently abstract a code template. To effectively integrate these multiple retrieval-augmented techniques, a comparative learning mechanism is designed to generate the final code. We validate the effectiveness of our approach on a dataset we build for deep learning code generation. Experimental results demonstrate that DLCodeGen outperforms other baselines, achieving improvements of 9.7% in CodeBLEU and 3.6% in human evaluation metrics.

Large language models (LLMs) have demonstrated a powerful ability to answer various queries as a general-purpose assistant. The continuous multi-modal large language models (MLLM) empower LLMs with the ability to perceive visual signals. The launch of GPT-4 (Generative Pre-trained Transformers) has generated significant interest in the research communities. GPT-4V(ison) has demonstrated significant power in both academia and industry fields, as a focal point in a new artificial intelligence generation. Though significant success was achieved by GPT-4V, exploring MLLMs in domain-specific analysis (e.g., marine analysis) that required domain-specific knowledge and expertise has gained less attention. In this study, we carry out the preliminary and comprehensive case study of utilizing GPT-4V for marine analysis. This report conducts a systematic evaluation of existing GPT-4V, assessing the performance of GPT-4V on marine research and also setting a new standard for future developments in MLLMs. The experimental results of GPT-4V show that the responses generated by GPT-4V are still far away from satisfying the domain-specific requirements of the marine professions. All images and prompts used in this study will be available at https://github.com/hkust-vgd/Marine_GPT-4V_Eval

With the rapid development of large language models (LLMs), they are not only used as general-purpose AI assistants but are also customized through further fine-tuning to meet the requirements of different applications. A pivotal factor in the success of current LLMs is the alignment process. Current alignment methods, such as supervised fine-tuning (SFT) and reinforcement learning from human feedback (RLHF), focus on training-time alignment and are often complex and cumbersome to implement. Therefore, we develop InferAligner, a novel inference-time alignment method that utilizes cross-model guidance for harmlessness alignment. InferAligner utilizes safety steering vectors extracted from safety-aligned model to modify the activations of the target model when responding to harmful inputs, thereby guiding the target model to provide harmless responses. Experimental results show that our method can be very effectively applied to domain-specific models in finance, medicine, and mathematics, as well as to multimodal large language models (MLLMs) such as LLaVA. It significantly diminishes the Attack Success Rate (ASR) of both harmful instructions and jailbreak attacks, while maintaining almost unchanged performance in downstream tasks.

Existing pruning techniques for large language models (LLMs) targeting domain-specific applications typically follow a two-stage process: pruning the pretrained general-purpose LLMs and then fine-tuning the pruned LLMs on specific domains. However, the pruning decisions, derived from the pretrained weights, remain unchanged during fine-tuning, even if the weights have been updated. Therefore, such a combination of the pruning decisions and the finetuned weights may be suboptimal, leading to non-negligible performance degradation. To address these limitations, we propose ATP: All-in-One Tuning and Structural Pruning, a unified one-stage structural pruning and fine-tuning approach that dynamically identifies the current optimal substructure throughout the fine-tuning phase via a trainable pruning decision generator. Moreover, given the limited available data for domain-specific applications, Low-Rank Adaptation (LoRA) becomes a common technique to fine-tune the LLMs. In ATP, we introduce LoRA-aware forward and sparsity regularization to ensure that the substructures corresponding to the learned pruning decisions can be directly removed after the ATP process. ATP outperforms the state-of-the-art two-stage pruning methods on tasks in the legal and healthcare domains. More specifically, ATP recovers up to 88% and 91% performance of the dense model when pruning 40% parameters of LLaMA2-7B and LLaMA3-8B models, respectively.

Large language models are trained in two stages: (1) unsupervised pretraining from raw text, to learn general-purpose representations, and (2) large scale instruction tuning and reinforcement learning, to better align to end tasks and user preferences. We measure the relative importance of these two stages by training LIMA, a 65B parameter LLaMa language model fine-tuned with the standard supervised loss on only 1,000 carefully curated prompts and responses, without any reinforcement learning or human preference modeling. LIMA demonstrates remarkably strong performance, learning to follow specific response formats from only a handful of examples in the training data, including complex queries that range from planning trip itineraries to speculating about alternate history. Moreover, the model tends to generalize well to unseen tasks that did not appear in the training data. In a controlled human study, responses from LIMA are either equivalent or strictly preferred to GPT-4 in 43% of cases; this statistic is as high as 58% when compared to Bard and 65% versus DaVinci003, which was trained with human feedback. Taken together, these results strongly suggest that almost all knowledge in large language models is learned during pretraining, and only limited instruction tuning data is necessary to teach models to produce high quality output.

Large Language Models (LLMs) exhibit impressive performance on a range of NLP tasks, due to the general-purpose linguistic knowledge acquired during pretraining. Existing model interpretability research (Tenney et al., 2019) suggests that a linguistic hierarchy emerges in the LLM layers, with lower layers better suited to solving syntactic tasks and higher layers employed for semantic processing. Yet, little is known about how encodings of different linguistic phenomena interact within the models and to what extent processing of linguistically-related categories relies on the same, shared model representations. In this paper, we propose a framework for testing the joint encoding of linguistic categories in LLMs. Focusing on syntax, we find evidence of joint encoding both at the same (related part-of-speech (POS) classes) and different (POS classes and related syntactic dependency relations) levels of linguistic hierarchy. Our cross-lingual experiments show that the same patterns hold across languages in multilingual LLMs.

Large language models (LLMs) have shown remarkable success across many domains, yet their integration into cybersecurity applications remains limited due to a lack of general-purpose cybersecurity data, representational complexity, and safety and regulatory concerns. To address this gap, we previously introduced Foundation-Sec-8B, a cybersecurity-focused LLM suitable for fine-tuning on downstream tasks. That model, however, was not designed for chat-style interactions or instruction-following. In this report, we release Foundation-Sec-8B-Instruct: a model specifically trained for general-purpose cybersecurity dialogue. Built on Foundation-Sec-8B, it combines domain-specific knowledge with instruction-following, conversational capabilities, and alignment with human preferences to produce high-quality, relevant responses. Comprehensive evaluations show that Foundation-Sec-8B-Instruct outperforms Llama 3.1-8B-Instruct on a range of cybersecurity tasks while matching its instruction-following performance. It is also competitive with GPT-4o-mini on cyber threat intelligence and instruction-following tasks. We envision Foundation-Sec-8B-Instruct becoming an indispensable assistant in the daily workflows of cybersecurity professionals. We release the model publicly at https://huggingface.co/fdtn-ai/Foundation-Sec-8B-Instruct.

Recent developments show that Large Language Models (LLMs) produce state-of-the-art performance on natural language (NL) to code generation for resource-rich general-purpose languages like C++, Java, and Python. However, their practical usage for structured domain-specific languages (DSLs) such as YAML, JSON is limited due to domain-specific schema, grammar, and customizations generally unseen by LLMs during pre-training. Efforts have been made to mitigate this challenge via in-context learning through relevant examples or by fine-tuning. However, it suffers from problems, such as limited DSL samples and prompt sensitivity but enterprises maintain good documentation of the DSLs. Therefore, we propose DocCGen, a framework that can leverage such rich knowledge by breaking the NL-to-Code generation task for structured code languages into a two-step process. First, it detects the correct libraries using the library documentation that best matches the NL query. Then, it utilizes schema rules extracted from the documentation of these libraries to constrain the decoding. We evaluate our framework for two complex structured languages, Ansible YAML and Bash command, consisting of two settings: Out-of-domain (OOD) and In-domain (ID). Our extensive experiments show that DocCGen consistently improves different-sized language models across all six evaluation metrics, reducing syntactic and semantic errors in structured code. We plan to open-source the datasets and code to motivate research in constrained code generation.

Developing artificial intelligence (AI) for vertical domains requires a solid data foundation for both training and evaluation. In this work, we introduce TrialPanorama, a large-scale, structured database comprising 1,657,476 clinical trial records aggregated from 15 global sources. The database captures key aspects of trial design and execution, including trial setups, interventions, conditions, biomarkers, and outcomes, and links them to standard biomedical ontologies such as DrugBank and MedDRA. This structured and ontology-grounded design enables TrialPanorama to serve as a unified, extensible resource for a wide range of clinical trial tasks, including trial planning, design, and summarization. To demonstrate its utility, we derive a suite of benchmark tasks directly from the TrialPanorama database. The benchmark spans eight tasks across two categories: three for systematic review (study search, study screening, and evidence summarization) and five for trial design (arm design, eligibility criteria, endpoint selection, sample size estimation, and trial completion assessment). The experiments using five state-of-the-art large language models (LLMs) show that while general-purpose LLMs exhibit some zero-shot capability, their performance is still inadequate for high-stakes clinical trial workflows. We release TrialPanorama database and the benchmark to facilitate further research on AI for clinical trials.

Leveraging massive knowledge and learning schemes from large language models (LLMs), recent machine learning models show notable successes in building generalist agents that exhibit the capability of general-purpose task solving in diverse domains, including natural language processing, computer vision, and robotics. However, a significant challenge remains as these models exhibit limited ability in understanding and interacting with the 3D world. We argue this limitation significantly hinders the current models from performing real-world tasks and further achieving general intelligence. To this end, we introduce an embodied multi-modal and multi-task generalist agent that excels in perceiving, grounding, reasoning, planning, and acting in the 3D world. Our proposed agent, referred to as LEO, is trained with shared LLM-based model architectures, objectives, and weights in two stages: (i) 3D vision-language alignment and (ii) 3D vision-language-action instruction tuning. To facilitate the training, we meticulously curate and generate an extensive dataset comprising object-level and scene-level multi-modal tasks with exceeding scale and complexity, necessitating a deep understanding of and interaction with the 3D world. Through rigorous experiments, we demonstrate LEO's remarkable proficiency across a wide spectrum of tasks, including 3D captioning, question answering, embodied reasoning, embodied navigation, and robotic manipulation. Our ablation results further provide valuable insights for the development of future embodied generalist agents.

Vision-language pre-training and instruction tuning have demonstrated general-purpose capabilities in 2D visual reasoning tasks by aligning visual encoders with state-of-the-art large language models (LLMs). In this paper, we introduce a simple, yet effective, cross-modality framework built atop frozen LLMs that allows the integration of various modalities without extensive modality-specific customization. To facilitate instruction-modality fine-tuning, we collect high-quality instruction tuning data in an automatic and scalable manner, composed of 24K QA samples for audio and 250K QA samples for 3D. Leveraging instruction-aware representations, our model performs comparably with leading-edge counterparts without the need of extensive modality-specific pre-training or customization. Furthermore, our approach demonstrates cross-modal reasoning abilities across two or more input modalities, despite each modality projection being trained individually. To study the model's cross-modal abilities, we contribute a novel Discriminative Cross-modal Reasoning (DisCRn) evaluation task, comprising 9K audio-video QA samples and 28K image-3D QA samples that require the model to reason discriminatively across disparate input modalities.

Can AI effectively perform complex econometric analysis traditionally requiring human expertise? This paper evaluates an agentic AI's capability to master econometrics, focusing on empirical analysis performance. We develop an ``Econometrics AI Agent'' built on the open-source MetaGPT framework. This agent exhibits outstanding performance in: (1) planning econometric tasks strategically, (2) generating and executing code, (3) employing error-based reflection for improved robustness, and (4) allowing iterative refinement through multi-round conversations. We construct two datasets from academic coursework materials and published research papers to evaluate performance against real-world challenges. Comparative testing shows our domain-specialized agent significantly outperforms both benchmark large language models (LLMs) and general-purpose AI agents. This work establishes a testbed for exploring AI's impact on social science research and enables cost-effective integration of domain expertise, making advanced econometric methods accessible to users with minimal coding expertise. Furthermore, our agent enhances research reproducibility and offers promising pedagogical applications for econometrics teaching.

Through the integration of external tools, large language models (LLMs) such as GPT-4o and Llama 3.1 significantly expand their functional capabilities, evolving from elementary conversational agents to general-purpose assistants. We argue that the primary drivers of these advancements are the quality and diversity of the training data. However, the existing LLMs with external tool integration provide only limited transparency regarding their datasets and data collection methods, which has led to the initiation of this research. Specifically, in this paper, our objective is to elucidate the detailed process involved in constructing datasets that empower LLMs to effectively learn how to utilize external tools and make this information available to the public through the introduction of ToolBridge. ToolBridge proposes to employ a collection of general open-access datasets as its raw dataset pool and applies a series of strategies to identify appropriate data entries from the pool for external tool API insertions. By supervised fine-tuning on these curated data entries, LLMs can invoke external tools in appropriate contexts to boost their predictive accuracy, particularly for basic functions including data processing, numerical computation, and factual retrieval. Our experiments rigorously isolates model architectures and training configurations, focusing exclusively on the role of data. The experimental results indicate that LLMs trained on ToolBridge demonstrate consistent performance improvements on both standard benchmarks and custom evaluation datasets. All the associated code and data will be open-source at https://github.com/CharlesPikachu/ToolBridge, promoting transparency and facilitating the broader community to explore approaches for equipping LLMs with external tools capabilities.

We present ACADATA, a high-quality parallel dataset for academic translation, that consists of two subsets: ACAD-TRAIN, which contains approximately 1.5 million author-generated paragraph pairs across 96 language directions and ACAD-BENCH, a curated evaluation set of almost 6,000 translations covering 12 directions. To validate its utility, we fine-tune two Large Language Models (LLMs) on ACAD-TRAIN and benchmark them on ACAD-BENCH against specialized machine-translation systems, general-purpose, open-weight LLMs, and several large-scale proprietary models. Experimental results demonstrate that fine-tuning on ACAD-TRAIN leads to improvements in academic translation quality by +6.1 and +12.4 d-BLEU points on average for 7B and 2B models respectively, while also improving long-context translation in a general domain by up to 24.9% when translating out of English. The fine-tuned top-performing model surpasses the best propietary and open-weight models on academic translation domain. By releasing ACAD-TRAIN, ACAD-BENCH and the fine-tuned models, we provide the community with a valuable resource to advance research in academic domain and long-context translation.

Automating software vulnerability detection (SVD) remains a critical challenge in an era of increasingly complex and interdependent software systems. Despite significant advances in Large Language Models (LLMs) for code analysis, prevailing evaluation methodologies often lack the context-aware robustness necessary to capture real-world intricacies and cross-component interactions. To address these limitations, we present VulnSage, a comprehensive evaluation framework and a dataset curated from diverse, large-scale open-source system software projects developed in C/C++. Unlike prior datasets, it leverages a heuristic noise pre-filtering approach combined with LLM-based reasoning to ensure a representative and minimally noisy spectrum of vulnerabilities. The framework supports multi-granular analysis across function, file, and inter-function levels and employs four diverse zero-shot prompt strategies: Baseline, Chain-of-Thought, Think, and Think & Verify. Through this evaluation, we uncover that structured reasoning prompts substantially improve LLM performance, with Think & Verify reducing ambiguous responses from 20.3% to 9.1% while increasing accuracy. We further demonstrate that code-specialized models consistently outperform general-purpose alternatives, with performance varying significantly across vulnerability types, revealing that no single approach universally excels across all security contexts. Link to dataset and codes: https://github.com/Erroristotle/VulnSage.git

Predicting human mobility is inherently challenging due to complex long-range dependencies and multi-scale periodic behaviors. To address this, we introduce RHYTHM (Reasoning with Hierarchical Temporal Tokenization for Human Mobility), a unified framework that leverages large language models (LLMs) as general-purpose spatio-temporal predictors and trajectory reasoners. Methodologically, RHYTHM employs temporal tokenization to partition each trajectory into daily segments and encode them as discrete tokens with hierarchical attention that captures both daily and weekly dependencies, thereby significantly reducing the sequence length while preserving cyclical information. Additionally, we enrich token representations by adding pre-computed prompt embeddings for trajectory segments and prediction targets via a frozen LLM, and feeding these combined embeddings back into the LLM backbone to capture complex interdependencies. Computationally, RHYTHM freezes the pretrained LLM's backbone to reduce attention complexity and memory cost. We evaluate our model against state-of-the-art methods using three real-world datasets. Notably, RHYTHM achieves a 2.4% improvement in overall accuracy, a 5.0% increase on weekends, and a 24.6% reduction in training time. Code is publicly available at https://github.com/he-h/rhythm.

This paper argues that a range of current AI systems have learned how to deceive humans. We define deception as the systematic inducement of false beliefs in the pursuit of some outcome other than the truth. We first survey empirical examples of AI deception, discussing both special-use AI systems (including Meta's CICERO) built for specific competitive situations, and general-purpose AI systems (such as large language models). Next, we detail several risks from AI deception, such as fraud, election tampering, and losing control of AI systems. Finally, we outline several potential solutions to the problems posed by AI deception: first, regulatory frameworks should subject AI systems that are capable of deception to robust risk-assessment requirements; second, policymakers should implement bot-or-not laws; and finally, policymakers should prioritize the funding of relevant research, including tools to detect AI deception and to make AI systems less deceptive. Policymakers, researchers, and the broader public should work proactively to prevent AI deception from destabilizing the shared foundations of our society.

Creating knowledge bases and ontologies is a time consuming task that relies on a manual curation. AI/NLP approaches can assist expert curators in populating these knowledge bases, but current approaches rely on extensive training data, and are not able to populate arbitrary complex nested knowledge schemas. Here we present Structured Prompt Interrogation and Recursive Extraction of Semantics (SPIRES), a Knowledge Extraction approach that relies on the ability of Large Language Models (LLMs) to perform zero-shot learning (ZSL) and general-purpose query answering from flexible prompts and return information conforming to a specified schema. Given a detailed, user-defined knowledge schema and an input text, SPIRES recursively performs prompt interrogation against GPT-3+ to obtain a set of responses matching the provided schema. SPIRES uses existing ontologies and vocabularies to provide identifiers for all matched elements. We present examples of use of SPIRES in different domains, including extraction of food recipes, multi-species cellular signaling pathways, disease treatments, multi-step drug mechanisms, and chemical to disease causation graphs. Current SPIRES accuracy is comparable to the mid-range of existing Relation Extraction (RE) methods, but has the advantage of easy customization, flexibility, and, crucially, the ability to perform new tasks in the absence of any training data. This method supports a general strategy of leveraging the language interpreting capabilities of LLMs to assemble knowledge bases, assisting manual knowledge curation and acquisition while supporting validation with publicly-available databases and ontologies external to the LLM. SPIRES is available as part of the open source OntoGPT package: https://github.com/ monarch-initiative/ontogpt.

Ribonucleic acid (RNA) plays a variety of crucial roles in fundamental biological processes. Recently, RNA has become an interesting drug target, emphasizing the need to improve our understanding of its structures and functions. Over the years, sequencing technologies have produced an enormous amount of unlabeled RNA data, which hides important knowledge and potential. Motivated by the successes of protein language models, we introduce RiboNucleic Acid Language Model (RiNALMo) to help unveil the hidden code of RNA. RiNALMo is the largest RNA language model to date with 650 million parameters pre-trained on 36 million non-coding RNA sequences from several available databases. RiNALMo is able to extract hidden knowledge and capture the underlying structure information implicitly embedded within the RNA sequences. RiNALMo achieves state-of-the-art results on several downstream tasks. Notably, we show that its generalization capabilities can overcome the inability of other deep learning methods for secondary structure prediction to generalize on unseen RNA families. The code has been made publicly available on https://github.com/lbcb-sci/RiNALMo.