Year
int64 2.02k
2.03k
| UI
stringlengths 7
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| UPDATED_FIELD
stringclasses 13
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stringlengths 1
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stringlengths 1
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| NOTES
stringclasses 19
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|---|---|---|---|---|---|
2,025
|
D000078625
|
MS
|
The act or practice of killing or withholding life-sustaining treatment from a person with a medical condition, especially DISABLED PERSONS, without INFORMED CONSENT, despite the MENTAL COMPETENCY of the person to give consent.
|
The act or practice of killing or withholding life-sustaining treatment from a person with a medical condition, especially PERSONS WITH DISABILITIES, without INFORMED CONSENT, despite the MENTAL COMPETENCY of the person to give consent.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000079262
|
NM
|
Obesity, Maternal
|
Pregnancy in Obesity
|
Preferred Term (MH) updated on a descriptor
|
2,025
|
D000079262
|
MS
|
BODY MASS INDEX in PREGNANT WOMEN that is excessively above the recommended cut-off.
|
BODY MASS INDEX in PREGNANT PEOPLE that is excessively above the recommended cut-off.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000079262
|
HN
|
2020
|
2025 (2020)
|
History note updated on a descriptor
|
2,025
|
D000079262
|
PM
|
2020
|
2025; see OBESITY, MATERNAL 2020-2024
|
Public MeSH note updated on a descriptor
|
2,025
|
D000080057
|
MS
|
A species of conifers commonly referred to as "pine", but does not belong in the genus Pinus. Araucaria angustifolia is widely distributed in Brazil and Argentina.
|
A species of conifers commonly referred to as pine, but does not belong in the genus Pinus. Araucaria angustifolia is widely distributed in Brazil and Argentina.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000080183
|
MS
|
Those individuals with INTERSEX CONDITIONS, with or without a desire to undergo SEX REASSIGNMENT PROCEDURES.
|
Those individuals with INTERSEX CONDITIONS, with or without a desire to undergo GENDER-AFFIRMING PROCEDURES.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000081822
|
MS
|
Dogs trained to serve as guides for blind or visually impaired persons.
|
Dogs trained to serve as guides for blind or PERSONS WITH VISUAL DISABILITIES.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000084002
|
NM
|
Tinea cruris
|
Tinea Cruris
|
Preferred Term (MH) updated on a descriptor
|
2,025
|
D000084662
|
MS
|
A species of Chytridiomycota fungi that is the causative agent of chytridiomycosis in amphibians.
|
A species of Chytridiomycota fungi that is the causative agent of CHYTRIDIOMYCOSIS IN AMPHIBIANS.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000085703
|
MS
|
Animals that provide emotional or therapeutic support to persons with mental disabilities or disorders. The designation "emotional support animal" requires a recommendation letter from a licensed psychologist or therapist, and provides some legal protections for the animal to live and travel with its owner.
|
Animals that provide emotional or therapeutic support to PERSONS WITH INTELLECTUAL DISABILITIES or disorders. The designation emotional support animal requires a recommendation letter from a licensed psychologist or therapist, and provides some legal protections for the animal to live and travel with its owner.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000086382
|
MS
|
A viral disorder generally characterized by high FEVER; COUGH; DYSPNEA; CHILLS; PERSISTENT TREMOR; MUSCLE PAIN; HEADACHE; SORE THROAT; a new loss of taste and/or smell (see AGEUSIA and ANOSMIA) and other symptoms of a VIRAL PNEUMONIA. In severe cases, a myriad of coagulopathy associated symptoms often correlating with COVID-19 severity is seen (e.g., BLOOD COAGULATION; THROMBOSIS; ACUTE RESPIRATORY DISTRESS SYNDROME; SEIZURES; HEART ATTACK; STROKE; multiple CEREBRAL INFARCTIONS; KIDNEY FAILURE; catastrophic ANTIPHOSPHOLIPID ANTIBODY SYNDROME and/or DISSEMINATED INTRAVASCULAR COAGULATION). In younger patients, rare inflammatory syndromes are sometimes associated with COVID-19 (e.g., atypical KAWASAKI SYNDROME; TOXIC SHOCK SYNDROME; pediatric multisystem inflammatory disease; and CYTOKINE STORM SYNDROME). A coronavirus, SARS-CoV-2, in the genus BETACORONAVIRUS is the causative agent.
|
A viral disorder generally characterized by high FEVER; COUGH; DYSPNEA; CHILLS; PERSISTENT TREMOR; MUSCLE PAIN; HEADACHE; SORE THROAT; a new loss of taste and/or smell (see AGEUSIA and ANOSMIA) and other symptoms of a VIRAL PNEUMONIA. A coronavirus, SARS-CoV-2 VIRUS, in the genus BETACORONAVIRUS is the causative agent.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000089122
|
MS
|
Fathers initially aged less than 19 years at the time of child's birth.
|
Fathers initially aged less than 19 years at the time of their child's birth.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000091182
|
MS
|
Traditional concepts of medicine and associated methods reflected in medicine in PERSIA.
|
Concepts of medicine and associated methods reflected in traditional Iranian medicine.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000091182
|
NM
|
Medicine, Persian
|
Medicine, Iranian Traditional
|
Preferred Term (MH) updated on a descriptor
|
2,025
|
D000092183
|
MS
|
A hypertrophic cardiomyopathy characterized by apical hypertrophy, typically LEFT VENTRICULAR HYPERTROPHY (described as "ace of spades" sign), and deep T-wave inversions in EKG. Clinical symptoms include minor symptoms such as CHEST PAIN; DYSPNEA; and SYNCOPE to more complex symptoms such as ATRIAL FIBRILLATION; VENTRICULAR FIBRILLATION; MYOCARDIAL INFARCTION and CONGESTIVE HEART FAILURE. A transient left ventricular apical hypertrophy is sometimes associated with TAKOTSUBO CARDIOMYOPATHY.
|
A hypertrophic cardiomyopathy characterized by apical hypertrophy, typically LEFT VENTRICULAR HYPERTROPHY (described as ace of spades sign), and deep T-wave inversions in EKG. Clinical symptoms include minor symptoms such as CHEST PAIN; DYSPNEA; and SYNCOPE to more complex symptoms such as ATRIAL FIBRILLATION; VENTRICULAR FIBRILLATION; MYOCARDIAL INFARCTION and CONGESTIVE HEART FAILURE. A transient left ventricular apical hypertrophy is sometimes associated with TAKOTSUBO CARDIOMYOPATHY.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000093102
|
MS
|
A device ridden while seated that usually has three or four wheels, is typically propelled by an electric motor, and is used by those with limited or impaired mobility.
|
A device ridden while seated that is typically propelled by an electric motor, and is used by those with limited or impaired mobility.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000094024
|
MS
|
Post acute stage of COVID-19 virus infection. Persistent symptoms may include FATIGUE; DYSPNEA; and MEMORY LOSS.
|
Post acute stage of COVID-19 virus infection including signs, symptoms, and conditions that continue or develop after acute COVID-19 infection. Persistent symptoms may include FATIGUE; DYSPNEA; and MEMORY LOSS.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000095188
|
MS
|
Persons having origins in any of PACIFIC ISLANDS. Note that OMB category NATIVE HAWAIIAN OR OTHER PACIFIC ISLANDER is available for United States population groups. Race and ethnicity terms, as used in the federal government, are self-identified social construct and may include terms outdated and offensive in MeSH to assist users who are interested in retrieving comprehensive search results for studies such as in longitudinal studies.
|
Persons having origins in any of PACIFIC ISLANDS. Note that OMB category NATIVE HAWAIIAN OR PACIFIC ISLANDER is available for United States population groups. Race and ethnicity terms, as used in the federal government, are self-identified social construct and may include terms outdated and offensive in MeSH to assist users who are interested in retrieving comprehensive search results for studies such as in longitudinal studies.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000095283
|
HN
|
2023
|
2023(1963)
|
History note updated on a descriptor
|
2,025
|
D000095494
|
MS
|
Psychoanalytic theory begun by Jacques Lacan as a philosophical linguistic re-interpretation of Freud's original teachings.
|
Psychoanalytic theory begun by Jacques Lacan as a philosophical linguistic re-interpretation of Freud's original teachings (see FREUDIAN THEORY).
|
MeSH scope note updated on a descriptor
|
2,025
|
D000095982
|
HN
|
2024
|
2025(2024)
|
History note updated on a descriptor
|
2,025
|
D000095982
|
PM
|
2024
|
2025(2024)
|
Public MeSH note updated on a descriptor
|
2,025
|
D000096283
|
MS
|
The emigration or immigration of individuals who have received advanced training at home. The net benefits of human capital flight for the receiving country are sometimes referred to as a "brain gain" whereas the costs for the sending country are sometimes referred to as a "brain drain".
|
The emigration or immigration of individuals who have received advanced training at home. The net benefits of human capital flight for the receiving country are sometimes referred to as a brain gain whereas the costs for the sending country are sometimes referred to as a brain drain.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000097623
|
PM
|
2024
|
2024; CEFPODOXIME was indexed under CEFTIZOXIME 1987-2024
|
Public MeSH note updated on a descriptor
|
2,025
|
D000097623
|
HN
|
2024
|
2024 (1987)
|
History note updated on a descriptor
|
2,025
|
D000097867
|
MS
|
Anesthesia methods that are used for neurologic medical procedures.
|
Anesthesia method that deals with the complexities of the physiology and pharmacology of the nervous system when providing anesthesia for patients undergoing neurological procedures.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000350
|
MS
|
The geographical area of Africa comprising CAMEROON; CENTRAL AFRICAN REPUBLIC; CHAD; CONGO; DEMOCRATIC REPUBLIC OF THE CONGO; EQUATORIAL GUINEA; GABON; and SAO TOME AND PRINCIPE.
|
The geographical area of Africa comprising CAMEROON; CENTRAL AFRICAN REPUBLIC; CHAD; CONGO; DEMOCRATIC REPUBLIC OF THE CONGO; EQUATORIAL GUINEA; GABON; RWANDA.and SAO TOME AND PRINCIPE.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000351
|
MS
|
The geographical area of Africa comprising BURUNDI, DJIBOUTI, ERITREA, ETHIOPIA, KENYA, RWANDA, SOMALIA, SOUTH SUDAN, SUDAN, TANZANIA, and UGANDA.
|
The geographical area of Africa comprising BURUNDI, DJIBOUTI, ERITREA, ETHIOPIA, KENYA, SOMALIA, SOUTH SUDAN, SUDAN, TANZANIA, and UGANDA.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000437
|
AN
|
human and animal; note entry term ALCOHOLIC INTOXICATION, CHRONIC: do not coordinate with CHRONIC DISEASE; available also are BINGE DRINKING, DRUNKENNESS see ALCOHOLIC INTOXICATION and ALCOHOLICS; acute alcoholic intoxication = ETHANOL /pois; consider also ALCOHOL-INDUCED DISORDERS and specifics; index other complications of alcoholism under ALCOHOLISM /compl + disease /etiol not /chem ind; abstinence from alcohol in alcoholism: coordinate with TEMPERANCE
|
human and animal; note entry term ALCOHOLIC INTOXICATION, CHRONIC: do not coordinate with CHRONIC DISEASE; available also are BINGE DRINKING, DRUNKENNESS see ALCOHOLIC INTOXICATION and ALCOHOLICS; acute alcoholic intoxication = ETHANOL/pois; consider also ALCOHOL-INDUCED DISORDERS and specifics; index other complications of alcoholism under ALCOHOLISM /compl + disease /etiol not /chem ind; abstinence from alcohol in alcoholism: coordinate with TEMPERANCE
|
Annotation updated on a descriptor
|
2,025
|
D000492
|
MS
|
An enzyme that catalyzes the hydrolysis of allophanic acid to two molecules of ammonia plus two molecules of "active carbon dioxide". EC 3.5.1.54.
|
An enzyme that catalyzes the hydrolysis of allophanic acid to two molecules of ammonia plus two molecules of active carbon dioxide. EC 3.5.1.54.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000559
|
MS
|
A family of the class Urodela which includes 4 living genera, about 33 species, and occurs only in North America. Adults are usually terrestrial, but the larval forms are aquatic.
|
A family of the class CAUDATA which includes 4 living genera, about 33 species, and occurs only in North America. Adults are usually terrestrial, but the larval forms are aquatic.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000915
|
MS
|
A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
|
A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of avidity, which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000920
|
MS
|
The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a "killer" cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.
|
The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a killer cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.
|
MeSH scope note updated on a descriptor
|
2,025
|
D000995
|
MS
|
Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.
|
Drugs used in the treatment of tuberculosis. They are divided into two main classes: first-line agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and second-line drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.
|
MeSH scope note updated on a descriptor
|
2,025
|
D001001
|
MS
|
An order of the class Amphibia, which includes several families of frogs and toads. They are characterized by well developed hind limbs adapted for jumping, fused head and trunk and webbed toes. The term "toad" is ambiguous and is properly applied only to the family Bufonidae.
|
An order of the class Amphibia, which includes several families of frogs and toads. They are characterized by well developed hind limbs adapted for jumping, fused head and trunk and webbed toes. The term toad is ambiguous and is properly applied only to the family Bufonidae.
|
MeSH scope note updated on a descriptor
|
2,025
|
D001068
|
MS
|
A group of disorders characterized by physiological and psychological disturbances in appetite or food intake.
|
A group of disorders characterized by physiological and/or psychological disturbances in appetite or food intake.
|
MeSH scope note updated on a descriptor
|
2,025
|
D001168
|
AN
|
tends to be chronic so do not coordinate with CHRONIC DISEASE; do not confuse with ARTHRALGIA; note entry term POLYARTHRITIS but polyarthrite chronique évolutive (PCE) = ARTHRITIS, RHEUMATOID; note several specific types of arthritis are available
|
tends to be chronic so do not coordinate with CHRONIC DISEASE; do not confuse with ARTHRALGIA; note entry term POLYARTHRITIS but polyarthrite chronique evolutive (PCE) = ARTHRITIS, RHEUMATOID; note several specific types of arthritis are available
|
Annotation updated on a descriptor
|
2,025
|
D001172
|
AN
|
in children = ARTHRITIS, JUVENILE RHEUMATOID; includes PCE: polyarthrite chronique évolutive; tends to be chronic so do not coord with CHRONIC DISEASE
|
in children = ARTHRITIS, JUVENILE RHEUMATOID; includes PCE: polyarthrite chronique evolutive; tends to be chronic so do not coord with CHRONIC DISEASE
|
Annotation updated on a descriptor
|
2,025
|
D001203
|
HN
|
99(75)
|
1999(1975)
|
History note updated on a descriptor
|
2,025
|
D001203
|
PM
|
99; see ASCOMYCETES 1963-98; for COCHLIOBOLUS & SCLEROTINA see ASCOMYCETES 1975-85
|
1999; see ASCOMYCETES 1963-1998; for COCHLIOBOLUS & SCLEROTINA see ASCOMYCETES 1975-1985
|
Public MeSH note updated on a descriptor
|
2,025
|
D001253
|
MS
|
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
|
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from star cells) are irregularly shaped with many long processes, including those with end feet which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and reactive astrocytes (along with MICROGLIA) respond to injury.
|
MeSH scope note updated on a descriptor
|
2,025
|
D001364
|
MS
|
The act of "taking account" of an object or state of affairs. It does not imply assessment of, nor attention to the qualities or nature of the object.
|
The act of taking account of an object or state of affairs. It does not imply assessment of, nor attention to the qualities or nature of the object.
|
MeSH scope note updated on a descriptor
|
2,025
|
D001445
|
MS
|
An independent state, an archipelago in the western Persian Gulf, northwest of Qatar. It comprises low-lying islands of Bahrain (the largest), Muharraq, Sitra, and several islets. It has extensive oil fields. The name comes from the Arabic al-bahrayn, "the two seas", with reference to its lying in the middle of a bay with its "two seas" east and west of it. (From Webster's New Geographical Dictionary, 1988, p107 & Room, Brewer's Dictionary of Names, 1992, p45)
|
An independent state, an archipelago in the western Persian Gulf, northwest of Qatar. It comprises low-lying islands of Bahrain (the largest), Muharraq, Sitra, and several islets. It has extensive oil fields. The name comes from the Arabic al-bahrayn, the two seas, with reference to its lying in the middle of a bay with its two seas east and west of it. (From Webster's New Geographical Dictionary, 1988, p107 & Room, Brewer's Dictionary of Names, 1992, p45)
|
MeSH scope note updated on a descriptor
|
2,025
|
D001452
|
MS
|
Therapy by various hot or warm baths in natural mineral waters, spas, or "cures". It includes not only bathing in, but also drinking the waters, but it does not include whirlpool baths (HYDROTHERAPY).
|
Therapy by various hot or warm baths in natural mineral waters, spas, or cures. It includes not only bathing in, but also drinking the waters, but it does not include whirlpool baths (HYDROTHERAPY).
|
MeSH scope note updated on a descriptor
|
2,025
|
D001460
|
MS
|
An island in the Lesser Antilles in the West Indies. It is chiefly of coral formation with no good harbors and only small streams. It was probably discovered by the Portuguese in the sixteenth century. The name was given by 16th-century Spanish explorers from barbados, the plural for "bearded", with reference to the beard-like leaves or trails of moss on the trees that grew there in abundance. (From Webster's New Geographical Dictionary, 1988, p116 & Room, Brewer's Dictionary of Names, 1992, p49)
|
An island in the Lesser Antilles in the West Indies. It is chiefly of coral formation with no good harbors and only small streams. It was probably discovered by the Portuguese in the sixteenth century. The name was given by 16th-century Spanish explorers from barbados, the plural for bearded, with reference to the beard-like leaves or trails of moss on the trees that grew there in abundance. (From Webster's New Geographical Dictionary, 1988, p116 & Room, Brewer's Dictionary of Names, 1992, p49)
|
MeSH scope note updated on a descriptor
|
2,025
|
D001487
|
HN
|
99
|
1999
|
History note updated on a descriptor
|
2,025
|
D001487
|
PM
|
99; see BASIDIOMYCETES 1963-98
|
1999; see BASIDIOMYCETES 1963-1998
|
Public MeSH note updated on a descriptor
|
2,025
|
D001559
|
HN
|
75
|
1975
|
History note updated on a descriptor
|
2,025
|
D001559
|
PM
|
75
|
1975
|
Public MeSH note updated on a descriptor
|
2,025
|
D001632
|
HN
|
68
|
1968
|
History note updated on a descriptor
|
2,025
|
D001632
|
PM
|
68
|
1968
|
Public MeSH note updated on a descriptor
|
2,025
|
D001759
|
MS
|
A fungal infection that may appear in two forms: 1, a primary lesion characterized by the formation of a small cutaneous nodule and small nodules along the lymphatics that may heal within several months; and 2, chronic granulomatous lesions characterized by thick crusts, warty growths, and unusual vascularity and infection in the middle or upper lobes of the lung.
|
A fungal infection by BLASTOMYCES that may appear in two forms: 1, a primary lesion characterized by the formation of a small cutaneous nodule and small nodules along the lymphatics that may heal within several months; and 2, chronic granulomatous lesions characterized by thick crusts, warty growths, and unusual vascularity and infection in the middle or upper lobes of the lung.
|
MeSH scope note updated on a descriptor
|
2,025
|
D001808
|
AN
|
general or unspecified only: prefer specifics and/or /blood supply with anatomical terms; permeability = VASCULAR PERMEABILITY see CAPILLARY PERMEABILITY; inflammation = VASCULITIS or its specifics; radiography of blood vessels = ANGIOGRAPHY
|
general or unspecified only: prefer specifics and/or /blood supply with anatomical terms; permeability = VASCULAR PERMEABILITY see CAPILLARY PERMEABILITY; inflammation = VASCULITIS or its specifics; radiography of blood vessels = ANGIOGRAPHY
|
Annotation updated on a descriptor
|
2,025
|
D002032
|
MS
|
Eating an excess amount of food in a short period of time, as seen in the disorder of BULIMIA NERVOSA. It is caused by an abnormal craving for food, or insatiable hunger also known as "ox hunger".
|
Eating an excess amount of food in a short period of time, as seen in the disorder of BULIMIA NERVOSA. It is caused by an abnormal craving for food, or insatiable hunger also known as ox hunger.
|
MeSH scope note updated on a descriptor
|
2,025
|
D002277
|
MS
|
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for "cancer."
|
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
|
MeSH scope note updated on a descriptor
|
2,025
|
D002491
|
MS
|
A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252)
|
A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into specific agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and nonspecific agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252)
|
MeSH scope note updated on a descriptor
|
2,025
|
D002531
|
MS
|
The part of brain that lies behind the BRAIN STEM in the posterior base of skull (CRANIAL FOSSA, POSTERIOR). It is also known as the "little brain" with convolutions similar to those of CEREBRAL CORTEX, inner white matter, and deep cerebellar nuclei. Its function is to coordinate voluntary movements, maintain balance, and learn motor skills.
|
The part of brain that lies behind the BRAIN STEM in the posterior base of skull (CRANIAL FOSSA, POSTERIOR). It is also known as the little brain with convolutions similar to those of CEREBRAL CORTEX, inner white matter, and deep cerebellar nuclei. Its function is to coordinate voluntary movements, maintain balance, and learn motor skills.
|
MeSH scope note updated on a descriptor
|
2,025
|
D002671
|
AN
|
consider also CHILD, GIFTED & MENTALLY DISABLED PERSONS; check also tag CHILD or specific
|
consider also CHILD, GIFTED & MENTALLY Persons with Disabilities; check also tag CHILD or specific
|
Annotation updated on a descriptor
|
2,025
|
D002695
|
MS
|
A family of the order CHLAMYDIALES, containing a single genus Simkania, and corresponding to the "microorganism Z" (Simkania Z).
|
A family of the order CHLAMYDIALES, containing a single genus Simkania, and corresponding to the microorganism Z (Simkania Z).
|
MeSH scope note updated on a descriptor
|
2,025
|
D002979
|
MS
|
Physiologic period, characterized by endocrine, somatic, and psychic changes with the termination of ovarian function in the female. It may also accompany the normal diminution of sexual activity in the male.
|
Physiologic period, characterized by endocrine and somatic changes with the termination of ovarian function in the female. It may also accompany the diminution of sexual activity in the male.
|
MeSH scope note updated on a descriptor
|
2,025
|
D003082
|
MS
|
Surgical resection of a portion of or the entire colon.
|
Surgical resection of a portion of or the entire COLON.
|
MeSH scope note updated on a descriptor
|
2,025
|
D003095
|
MS
|
Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)
|
Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that collagen was equivalent to connective tissue, but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term collagen diseases now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)
|
MeSH scope note updated on a descriptor
|
2,025
|
D003134
|
PM
|
83; was see under FORENSIC PSYCHIATRY 1975-82
|
2025; COMMITMENT OF PERSONS WITH MENTAL ILLNESS 2024-83; was see under FORENSIC PSYCHIATRY 1975-82
|
Public MeSH note updated on a descriptor
|
2,025
|
D003134
|
NM
|
Commitment of Mentally Ill
|
Commitment of Persons with Psychiatric Disorders
|
Preferred Term (MH) updated on a descriptor
|
2,025
|
D003134
|
MS
|
Legal process required for the institutionalization of a patient with severe mental problems.
|
Legal process required for the institutionalization of a patient with severe psychiatric problems.
|
MeSH scope note updated on a descriptor
|
2,025
|
D003134
|
HN
|
83(75); was see under FORENSIC PSYCHIATRY 1975-82
|
2025; COMMITMENT OF PERSONS WITH MENTAL ILLNESS 2024-83; was see under FORENSIC PSYCHIATRY 1975-82
|
History note updated on a descriptor
|
2,025
|
D003143
|
NM
|
Communication Aids for Disabled
|
Communication Devices for People with Disabilities
|
Preferred Term (MH) updated on a descriptor
|
2,025
|
D003213
|
HN
|
2020 (1965); was CONDITIONING (PSYCHOLOGY) 1965-2019; was CONDITIONED LEARNING 1963-1964
|
2020 (1965); was CONDITIONING (PSYCHOLOGY) 1965-2019; was CONDITIONED LEARNING 1963-1964; SOCIAL LEARNING THEORY 2024 use SOCIAL LEARNING 2024-;
|
History note updated on a descriptor
|
2,025
|
D003213
|
PM
|
1965; was CONDITIONED LEARNING 1963-1964
|
1965; was CONDITIONED LEARNING 1963-1964; SOCIAL LEARNING THEORY 2024 see SOCIAL LEARNING 2024-
|
Public MeSH note updated on a descriptor
|
2,025
|
D003218
|
MS
|
Sexually transmitted form of anogenital warty growth caused by the human papillomaviruses.
|
Sexually transmitted form of anogenital warty growth caused by the HUMAN PAPILLOMAVIRUS VIRUSES.
|
MeSH scope note updated on a descriptor
|
2,025
|
D003228
|
AN
|
inflammation = CONJUNCTIVITIS or specifics; do not confuse with "conjunctive tissue" in translated texts: this is CONNECTIVE TISSUE, not CONJUNCTIVA; /blood supply consider also CILIARY ARTERIES
|
inflammation = CONJUNCTIVITIS or specifics; do not confuse with "conjunctive tissue" in translated texts: this is CONNECTIVE TISSUE, not CONJUNCTIVA; /blood supply consider also CILIARY ARTERIES
|
Annotation updated on a descriptor
|
2,025
|
D003480
|
PM
|
99; see CUSHING'S SYNDROME 1966-98
|
1999; see CUSHING'S SYNDROME 1966-1998
|
Public MeSH note updated on a descriptor
|
2,025
|
D003480
|
HN
|
99(66)
|
1999(1966)
|
History note updated on a descriptor
|
2,025
|
D003602
|
MS
|
The phenomenon of target cell destruction by immunologically active effector cells. It may be brought about directly by sensitized T-lymphocytes or by lymphoid or myeloid "killer" cells, or it may be mediated by cytotoxic antibody, cytotoxic factor released by lymphoid cells, or complement.
|
The phenomenon of target cell destruction by immunologically active effector cells. It may be brought about directly by sensitized T-lymphocytes or by lymphoid or myeloid killer cells, or it may be mediated by cytotoxic antibody, cytotoxic factor released by lymphoid cells, or complement.
|
MeSH scope note updated on a descriptor
|
2,025
|
D003700
|
MS
|
Brain waves seen on EEG characterized by a high amplitude and a frequency of 4 Hz and below. They are considered the "deep sleep waves" observed during sleep in dreamless states, infancy, and in some brain disorders.
|
Brain waves seen on EEG characterized by a high amplitude and a frequency of 4 Hz and below. They are considered the deep sleep waves observed during sleep in dreamless states, infancy, and in some brain disorders.
|
MeSH scope note updated on a descriptor
|
2,025
|
D003730
|
HN
|
93; was DENTAL CARE FOR HANDICAPPED 1980-92
|
DENTAL CARE FOR HANDICAPPED 1980-1992; DENTAL CARE FOR DISABLED 1993-2024
|
History note updated on a descriptor
|
2,025
|
D003730
|
PM
|
93; was DENTAL CARE FOR HANDICAPPED 1980-92
|
DENTAL CARE FOR HANDICAPPED 1980-1992; DENTAL CARE FOR DISABLED 1993-2024
|
Public MeSH note updated on a descriptor
|
2,025
|
D003730
|
NM
|
Dental Care for Disabled
|
Dental Care for Persons with Disabilities
|
Preferred Term (MH) updated on a descriptor
|
2,025
|
D003744
|
HN
|
66; was ENAMEL HYPOPLASIA 1965
|
1966 (1965)
|
History note updated on a descriptor
|
2,025
|
D003744
|
PM
|
66; was ENAMEL HYPOPLASIA 1965
|
1966; see ENAMEL HYPOPLASIA 1965
|
Public MeSH note updated on a descriptor
|
2,025
|
D003865
|
MS
|
Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
|
Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every day; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
|
MeSH scope note updated on a descriptor
|
2,025
|
D003883
|
HN
|
99; for ARTHRODERMA use ASCOMYCOTA 1975-98; for NANNIZZIA use MICROSPORUM 1975-98
|
1999; for ARTHRODERMA use ASCOMYCOTA 1975-1998; for NANNIZZIA use MICROSPORUM 1975-1998
|
History note updated on a descriptor
|
2,025
|
D003883
|
PM
|
99; see DERMATOPHYTES 1963-98; for ARTHRODERMA see ASCOMYCOTA 1975-98; for NANNIZZIA see MICROSPORUM 1975-98
|
1999; see DERMATOPHYTES 1963-1998; for ARTHRODERMA see ASCOMYCOTA 1975-1998; for NANNIZZIA see MICROSPORUM 1975-1998
|
Public MeSH note updated on a descriptor
|
2,025
|
D003932
|
PM
|
99; see DIACETYLMORPHINE 1978-98; for HEROIN see DIACETYLMORPHINE 1963-98
|
1999; see DIACETYLMORPHINE 1978-1998; for HEROIN see DIACETYLMORPHINE 1963-1998
|
Public MeSH note updated on a descriptor
|
2,025
|
D003932
|
HN
|
99(63)
|
1999(1963)
|
History note updated on a descriptor
|
2,025
|
D004043
|
AN
|
/adv eff: coordinate with disease /etiol, not /chem ind; /ther use: coordinate with specific disease /diet ther; low- or high-fiber diet: use /admin
|
/ adv eff: coordinate with disease /etiol, not /chem ind; /ther use: coordinate with specific disease /diet ther; low- or high-fiber diet: use /admin
|
Annotation updated on a descriptor
|
2,025
|
D004044
|
AN
|
general or unspecified; prefer specifics; /adv eff: coordinate with disease /etiol, not /chem ind; /ther use: coordinate with disease /diet ther
|
general or unspecified; prefer specifics; /adv eff: coordinate with disease /etiol, not /chem ind; /ther use: coordinate with disease /diet ther/
|
Annotation updated on a descriptor
|
2,025
|
D004124
|
MS
|
A reagent used mainly to induce experimental liver cancer. According to the Fourth Annual Report on Carcinogens (NTP 85-002, p. 89) published in 1985, this compound "may reasonably be anticipated to be a carcinogen." (Merck, 11th ed)
|
A reagent used mainly to induce experimental liver cancer. According to the Fourth Annual Report on Carcinogens (NTP 85-002, p. 89) published in 1985, this compound may reasonably be anticipated to be a carcinogen. (Merck, 11th ed)
|
MeSH scope note updated on a descriptor
|
2,025
|
D004245
|
MS
|
Decayed, missing and filled teeth, a routinely used statistical concept in dentistry.
|
Decayed, missing and filled teeth, a routinely used statistical concept in dentistry.
|
MeSH scope note updated on a descriptor
|
2,025
|
D004454
|
MS
|
Involuntary ("parrot-like"), meaningless repetition of a recently heard word, phrase, or song. This condition may be associated with transcortical APHASIA; SCHIZOPHRENIA; or other disorders. (From Adams et al., Principles of Neurology, 6th ed, p485)
|
Involuntary (parrot-like), meaningless repetition of a recently heard word, phrase, or song. This condition may be associated with transcortical APHASIA; SCHIZOPHRENIA; or other disorders. (From Adams et al., Principles of Neurology, 6th ed, p485)
|
MeSH scope note updated on a descriptor
|
2,025
|
D004495
|
PM
|
67; was EDUCATION OF MENTALLY DEFECTIVE 1963-66
|
2025; was EDUCATION OF INTELLECTUALLY DISABLED 1967-2024; was EDUCATION OF MENTALLY DEFECTIVE 1963-1966
|
Public MeSH note updated on a descriptor
|
2,025
|
D004495
|
NM
|
Education of Intellectually Disabled
|
Education of Persons with Intellectual Disabilities
|
Preferred Term (MH) updated on a descriptor
|
2,025
|
D004495
|
HN
|
67; was EDUCATION OF MENTALLY DEFECTIVE 1963-66
|
2025 (1967)
|
History note updated on a descriptor
|
2,025
|
D004767
|
MS
|
Disease caused by the liberation of exotoxins of CLOSTRIDIUM PERFRINGENS in the intestines of sheep, goats, cattle, foals, and piglets. Type B enterotoxemia in lambs is lamb dysentery; type C enterotoxemia in mature sheep produces "struck", and in calves, lambs and piglets it produces hemorrhagic enterotoxemia; type D enterotoxemia in sheep and goats is pulpy-kidney disease or overeating disease.
|
Disease caused by the liberation of exotoxins of CLOSTRIDIUM PERFRINGENS in the intestines of sheep, goats, cattle, foals, and piglets. Type B enterotoxemia in lambs is lamb dysentery; type C enterotoxemia in mature sheep produces struck, and in calves, lambs and piglets it produces hemorrhagic enterotoxemia; type D enterotoxemia in sheep and goats is pulpy-kidney disease or overeating disease.
|
MeSH scope note updated on a descriptor
|
2,025
|
D004770
|
MS
|
A genus of the family PICORNAVIRIDAE whose members preferentially inhabit the intestinal tract of a variety of hosts. The genus contains many species. Newly described members of human enteroviruses are assigned continuous numbers with the species designated "human enterovirus".
|
A genus of the family PICORNAVIRIDAE whose members preferentially inhabit the intestinal tract of a variety of hosts. The genus contains many species. Newly described members of human enteroviruses are assigned continuous numbers with the species designated human enterovirus.
|
MeSH scope note updated on a descriptor
|
2,025
|
D004813
|
AN
|
specialty only; prefer /epidemiol with diseases; do not confuse with TOPOGRAPHY, MEDICAL: epidemiology emphasizes disease outbreaks & disease-related conditions, topography emphasizes geography-related events
|
specialty only; prefer /epidemiol with diseases; do not confuse with TOPOGRAPHY, MEDICAL: epidemiology emphasizes disease outbreaks & disease-related conditions, topography emphasizes geography-related events
|
Annotation updated on a descriptor
|
2,025
|
D004892
|
MS
|
A skin and mucous membrane disease characterized by an eruption of macules, papules, nodules, vesicles, and/or bullae with characteristic "bull's-eye" lesions usually occurring on the dorsal aspect of the hands and forearms.
|
A skin and mucous membrane disease characterized by an eruption of macules, papules, nodules, vesicles, and/or bullae with characteristic bull's-eye lesions usually occurring on the dorsal aspect of the hands and forearms.
|
MeSH scope note updated on a descriptor
|
2,025
|
D004948
|
MS
|
A form of ocular misalignment characterized by an excessive convergence of the visual axes, resulting in a "cross-eye" appearance. An example of this condition occurs when paralysis of the lateral rectus muscle causes an abnormal inward deviation of one eye on attempted gaze.
|
A form of ocular misalignment characterized by an excessive convergence of the visual axes, resulting in a cross-eye appearance. An example of this condition occurs when paralysis of the lateral rectus muscle causes an abnormal inward deviation of one eye on attempted gaze.
|
MeSH scope note updated on a descriptor
|
2,025
|
D005053
|
MS
|
The attempt to improve the PHENOTYPES of future generations of the human population by fostering the reproduction of those with favorable phenotypes and GENOTYPES and hampering or preventing BREEDING by those with "undesirable" phenotypes and genotypes. The concept is largely discredited. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
|
The attempt to improve the PHENOTYPES of future generations of the human population by fostering the reproduction of those with favorable phenotypes and GENOTYPES and hampering or preventing BREEDING by those with undesirable phenotypes and genotypes. The concept is largely discredited. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
|
MeSH scope note updated on a descriptor
|
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